Primary Site >> Stomach Cancer
Gene >> CHEK2
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Ref: Absence of germline CHK2 mutations in familial gastric cancer. PMID: 11011113 |
Ref: Mutation analysis of the CHK2 gene in breast carcinoma and other cancers. PMID: 12052256 |
Ref: Identification and characterization of a novel p42.3 gene as tumor-specific and mitosis phase-dependent expression in gastric cancer. PMID: 17525738 Ref: Increased wild-type p53-induced phosphatase 1 (Wip1 or PPM1D) expression correlated with downregulation of checkpoint kinase 2 in human gastric carcinoma. PMID: 17685927 |
Ref: Synergistic interaction between trifluorothymidine and docetaxel is sequence dependent. PMID: 18957056 |
Ref: Growth inhibitory effect and Chk1-dependent signaling involved in G2/M arrest on human gastric cancer cells induced by diallyl disulfide. PMID: 20401435 |
Ref: Xanthatin induces G2/M cell cycle arrest and apoptosis in human gastric carcinoma MKN-45 cells. PMID: 22532019 |
Ref: Targeting Chk2 improves gastric cancer chemotherapy by impairing DNA damage repair. PMID: 23271172 Ref: The risk of gastric cancer in carriers of CHEK2 mutations. PMID: 23296741 Ref: Genetic variants in DNA repair pathway genes and risk of esophageal squamous cell carcinoma and gastric adenocarcinoma in a Chinese population. PMID: 23504502 |
Ref: DNA damage response-related proteins in gastric cancer: ATM, Chk2 and p53 expression and their prognostic value. PMID: 23969480 Ref: Antitumor activity of di-n-butyl-(2,6-difluorobenzohydroxamato)tin(IV) against human gastric carcinoma SGC-7901 cells via G2/M cell cycle arrest and cell apoptosis. PMID: 24643073 Ref: Chk1, but not Chk2, is responsible for G2/M phase arrest induced by diallyl disulfide in human gastric cancer BGC823 cells. PMID: 24650757 Ref: Diallyl disulfide selectively causes checkpoint kinase-1 mediated G2/M arrest in human MGC803 gastric cancer cell line. PMID: 25176258 |
Ref: Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer. PMID: 26857264 Ref: Increased Risk for Other Cancers in Addition to Breast Cancer for CHEK2*1100delC Heterozygotes Estimated From the Copenhagen General Population Study. PMID: 26884562 Ref: [Jaridonin, a new diterpenoid from Isodon rubescens, induces cell cycle arrest in gastric cancer cells through activating ataxia telangiectasia mutated kinase]. PMID: 27087371 Ref: miR-30a can inhibit DNA replication by targeting RPA1 thus slowing cancer cell proliferation. PMID: 27208176 |
Ref: AZD6738, A Novel Oral Inhibitor of ATR, Induces Synthetic Lethality with ATM Deficiency in Gastric Cancer Cells. PMID: 28138034 Ref: DNA damage repair and survival outcomes in advanced gastric cancer patients treated with first-line chemotherapy. PMID: 28233295 Ref: Effect of diterpenoid kaurenoic acid on genotoxicity and cell cycle progression in gastric cancer cell lines. PMID: 28273639 Ref: Associations between mutations of the cell cycle checkpoint kinase 2 gene and gastric carcinogenesis. PMID: 29067458 |
Ref: FPHPB inhibits gastric tumor cell proliferation by inducing G2-M cell cycle arrest. PMID: 29304495 Ref: Expression of DNA damage response proteins in gastric cancer: Comprehensive protein profiling and histological analysis. PMID: 29328366 Ref: Men seeking counselling in a Breast Cancer Risk Evaluation Clinic. PMID: 29456621 Ref: Protective effect of the BET protein inhibitor JQ1 in cisplatin-induced nephrotoxicity. PMID: 29767555 |