Primary Site >> Liver Cancer

Gene >> CHEK1

Journal: J Cell Biochem. 2008 Jul 1;104(4):1181-91.
Title: Involvement of the role of Chk1 in lithium-induced G2/M phase cell cycle arrest in hepatocellular carcinoma cells.
Author: Wang, Xiao-Ming|Li, Jiao|Feng, Xiao-Cheng|Wang, Qiong|Guan, Dong-Yin|Shen, Zong-Hou
PMID: 18247328
Journal: Oncol Rep. 2008 Oct;20(4):863-72.
Title: The growth inhibition of hepatocellular and cholangiocellular carcinoma cells by gemcitabine and the roles of extracellular signal-regulated and checkpoint kinases.
Author: Matsumoto, Kazuya|Nagahara, Takakazu|Okano, Jun-Ichi|Murawaki, Yoshikazu
PMID: 18813828
Journal: Toxicol Sci. 2009 Sep;111(1):120-30.
Title: Long-term exposure to zidovudine delays cell cycle progression, induces apoptosis, and decreases telomerase activity in human hepatocytes.
Author: Fang, Jia-Long|Beland, Frederick A
PMID: 19541796
Journal: Toxicol Sci. 2010 Dec;118(2):404-10.
Title: PPARalpha-dependent activation of cell cycle control and DNA repair genes in hepatic nonparenchymal cells.
Author: Qu, Aijuan|Shah, Yatrik M|Matsubara, Tsutomu|Yang, Qian|Gonzalez, Frank J
PMID: 20813756
Journal: Toxicol In Vitro. 2013 Sep;27(6):1809-19.
Title: Cylindrospermopsin induced transcriptional responses in human hepatoma HepG2 cells.
Author: Straser, Alja|Filipic, Metka|Zegura, Bojana
PMID: 23726867
Journal: J Biol Chem. 2013 Jul 12;288(28):20532-46.
Title: 4-Hydroxynonenal induces G2/M phase cell cycle arrest by activation of the ataxia telangiectasia mutated and Rad3-related protein (ATR)/checkpoint kinase 1 (Chk1) signaling pathway.
Author: Chaudhary, Pankaj|Sharma, Rajendra|Sahu, Mukesh|Vishwanatha, Jamboor K|Awasthi, Sanjay|Awasthi, Yogesh C
PMID: 23733185
Journal: Sci Rep. 2015 Apr 9;5:9357.
Title: Enhancer of rudimentary homolog regulates DNA damage response in hepatocellular carcinoma.
Author: Weng, Meng-Tzu|Tung, Tzu-Hsun|Lee, Jih-Hsiang|Wei, Shu-Chen|Lin, Hang-Li|Huang, Yu-Jung|Wong, Jau-Min|Luo, Ji|Sheu, Jin-Chuan
PMID: 25880358
Journal: World J Gastroenterol. 2016 Jun 28;22(24):5558-67.
Title: Relationships between cell cycle pathway gene polymorphisms and risk of hepatocellular carcinoma.
Author: Nan, Yue-Li|Hu, Yan-Ling|Liu, Zhi-Ke|Duan, Fang-Fang|Xu, Yang|Li, Shu|Li, Ting|Chen, Da-Fang|Zeng, Xiao-Yun
PMID: 27350734
Journal: Biomed Pharmacother. 2017 Aug;92:989-997.
Title: JS-K, a nitric oxide prodrug, induces DNA damage and apoptosis in HBV-positive hepatocellular carcinoma HepG2.2.15 cell.
Author: Liu, Zhengyun|Li, Guangmin|Gou, Ying|Xiao, Dongyan|Luo, Guo|Saavedra, Joseph E|Liu, Jie|Wang, Huan
PMID: 28605880
Journal: Biomed Res Int. 2018 Aug 29;2018:1431396.
Title: Analysis of Transcription Factor-Related Regulatory Networks Based on Bioinformatics Analysis and Validation in Hepatocellular Carcinoma.
Author: Liu, Shui|Yao, Xiaoxiao|Zhang, Dan|Sheng, Jiyao|Wen, Xin|Wang, Qingyu|Chen, Gaoyang|Li, Zhaoyan|Du, Zhenwu|Zhang, Xuewen
PMID: 30228980
Journal: Cell Death Dis. 2018 Oct 12;9(10):1045.
Title: MiR-126 negatively regulates PLK-4 to impact the development of hepatocellular carcinoma via ATR/CHEK1 pathway.
Author: Bao, Jie|Yu, Yan|Chen, Jianan|He, Yuting|Chen, Xiaolong|Ren, Zhigang|Xue, Chen|Liu, Liwen|Hu, Qiuyue|Li, Juan|Cui, Guangying|Sun, Ranran
PMID: 30315225
Journal: Biomed Res Int. 2018 Sep 30;2018:7897346.
Title: Upregulation of BUB1B, CCNB1, CDC7, CDC20, and MCM3 in Tumor Tissues Predicted Worse Overall Survival and Disease-Free Survival in Hepatocellular Carcinoma Patients.
Author: Zhuang, Liping|Yang, Zongguo|Meng, Zhiqiang
PMID: 30363964