Primary Site >> Liver Cancer
Gene >> CHEK1
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Ref: Involvement of the role of Chk1 in lithium-induced G2/M phase cell cycle arrest in hepatocellular carcinoma cells. PMID: 18247328 Ref: The growth inhibition of hepatocellular and cholangiocellular carcinoma cells by gemcitabine and the roles of extracellular signal-regulated and checkpoint kinases. PMID: 18813828 |
Ref: Long-term exposure to zidovudine delays cell cycle progression, induces apoptosis, and decreases telomerase activity in human hepatocytes. PMID: 19541796 |
Ref: PPARalpha-dependent activation of cell cycle control and DNA repair genes in hepatic nonparenchymal cells. PMID: 20813756 |
Ref: Cylindrospermopsin induced transcriptional responses in human hepatoma HepG2 cells. PMID: 23726867 Ref: 4-Hydroxynonenal induces G2/M phase cell cycle arrest by activation of the ataxia telangiectasia mutated and Rad3-related protein (ATR)/checkpoint kinase 1 (Chk1) signaling pathway. PMID: 23733185 |
Ref: Enhancer of rudimentary homolog regulates DNA damage response in hepatocellular carcinoma. PMID: 25880358 |
Ref: Relationships between cell cycle pathway gene polymorphisms and risk of hepatocellular carcinoma. PMID: 27350734 |
Ref: JS-K, a nitric oxide prodrug, induces DNA damage and apoptosis in HBV-positive hepatocellular carcinoma HepG2.2.15 cell. PMID: 28605880 |
Ref: Analysis of Transcription Factor-Related Regulatory Networks Based on Bioinformatics Analysis and Validation in Hepatocellular Carcinoma. PMID: 30228980 Ref: MiR-126 negatively regulates PLK-4 to impact the development of hepatocellular carcinoma via ATR/CHEK1 pathway. PMID: 30315225 Ref: Upregulation of BUB1B, CCNB1, CDC7, CDC20, and MCM3 in Tumor Tissues Predicted Worse Overall Survival and Disease-Free Survival in Hepatocellular Carcinoma Patients. PMID: 30363964 |