Primary Site >> Colorectal Cancer

Gene >> CFTR

Journal: Nucleic Acids Res. 1991 Oct 11;19(19):5417-23.
Title: Expression of the cystic fibrosis transmembrane conductance regulator gene in cells of non-epithelial origin.
Author: Yoshimura, K|Nakamura, H|Trapnell, B C|Chu, C S|Dalemans, W|Pavirani, A|Lecocq, J P|Crystal, R G
PMID: 1717947
Journal: J Biol Chem. 1992 Jan 25;267(3):2087-95.
Title: Biochemical characterization of the cystic fibrosis transmembrane conductance regulator in normal and cystic fibrosis epithelial cells.
Author: Sarkadi, B|Bauzon, D|Huckle, W R|Earp, H S|Berry, A|Suchindran, H|Price, E M|Olson, J C|Boucher, R C|Scarborough, G A
PMID: 1370488
Journal: J Biol Chem. 1992 Aug 15;267(23):16056-60.
Title: Expression of the cystic fibrosis transmembrane conductance regulator gene can be regulated by protein kinase C.
Author: Bargon, J|Trapnell, B C|Yoshimura, K|Dalemans, W|Pavirani, A|Lecocq, J P|Crystal, R G
PMID: 1379589
Journal: Proc Natl Acad Sci U S A. 1992 Jun 15;89(12):5562-6.
Title: A1 adenosine-receptor antagonists activate chloride efflux from cystic fibrosis cells.
Author: Eidelman, O|Guay-Broder, C|van Galen, P J|Jacobson, K A|Fox, C|Turner, R J|Cabantchik, Z I|Pollard, H B
PMID: 1376923
Journal: Mol Cell Biol. 1992 Apr;12(4):1872-8.
Title: Down-regulation of cystic fibrosis transmembrane conductance regulator gene expression by agents that modulate intracellular divalent cations.
Author: Bargon, J|Trapnell, B C|Chu, C S|Rosenthal, E R|Yoshimura, K|Guggino, W B|Dalemans, W|Pavirani, A|Lecocq, J P|Crystal, R G
PMID: 1372390
Journal: Nucleic Acids Res. 1994 Oct 25;22(21):4470-6.
Title: Transfer of a constitutive viral promoter-cystic fibrosis transmembrane conductance regulator cDNA to human epithelial cells conveys resistance to down-regulation of cAMP-regulated Cl- secretion in the presence of inflammatory stimuli.
Author: Kobayashi, N|Rosenthal, E R|Yoshimura, K|Crystal, R G
PMID: 7526342
Journal: J Clin Invest. 1995 Aug;96(2):822-30.
Title: Endogenous expression of type II cGMP-dependent protein kinase mRNA and protein in rat intestine. Implications for cystic fibrosis transmembrane conductance regulator.
Author: Markert, T|Vaandrager, A B|Gambaryan, S|Pohler, D|Hausler, C|Walter, U|De Jonge, H R|Jarchau, T|Lohmann, S M
PMID: 7543493
Journal: Proc Natl Acad Sci U S A. 1995 Aug 1;92(16):7560-4.
Title: Basal expression of the cystic fibrosis transmembrane conductance regulator gene is dependent on protein kinase A activity.
Author: McDonald, R A|Matthews, R P|Idzerda, R L|McKnight, G S
PMID: 7543684
Journal: Cell Mol Biol (Noisy-le-grand). 1996 Jul;42(5):797-804.
Title: Identification by differential display of a mRNA specifically induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in T84 human colon carcinoma cells.
Author: Cafferata, E G|Gonzalez-Guerrico, A M|Pivetta, O H|Santa-Coloma, T A
PMID: 8832110
Journal: J Biol Chem. 1996 Dec 13;271(50):31869-77.
Title: Characterization of the cAMP response element of the cystic fibrosis transmembrane conductance regulator gene promoter.
Author: Matthews, R P|McKnight, G S
PMID: 8943230
Journal: J Cell Physiol. 1998 Sep;176(3):472-81.
Title: Interrelationship between the Na+/glucose cotransporter and CFTR in Caco-2 cells: relevance to cystic fibrosis.
Author: Mailleau, C|Capeau, J|Brahimi-Horn, M C
PMID: 9699500
Journal: Glycobiology. 1999 Apr;9(4):389-98.
Title: CFTR expression does not influence glycosylation of an epitope-tagged MUC1 mucin in colon carcinoma cell lines.
Author: Reid, C J|Burdick, M D|Hollingsworth, M A|Harris, A
PMID: 10089213
Journal: Cancer Res. 2000 Sep 15;60(18):5151-7.
Title: Uroguanylin treatment suppresses polyp formation in the Apc(Min/+) mouse and induces apoptosis in human colon adenocarcinoma cells via cyclic GMP.
Author: Shailubhai, K|Yu, H H|Karunanandaa, K|Wang, J Y|Eber, S L|Wang, Y|Joo, N S|Kim, H D|Miedema, B W|Abbas, S Z|Boddupalli, S S|Currie, M G|Forte, L R
PMID: 11016642
Journal: Hum Mol Genet. 2001 Jul 1;10(14):1455-64.
Title: An element in intron 1 of the CFTR gene augments intestinal expression in vivo.
Author: Rowntree, R K|Vassaux, G|McDowell, T L|Howe, S|McGuigan, A|Phylactides, M|Huxley, C|Harris, A
PMID: 11448937
Journal: Physiol Rev. 2002 Jan;82(1):245-89.
Title: Electrolyte transport in the mammalian colon: mechanisms and implications for disease.
Author: Kunzelmann, Karl|Mall, Marcus
PMID: 11773614
Journal: Hum Gene Ther. 2002 Jan 1;13(1):15-63.
Title: Safety of local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of morbid conditions.
Author: Harvey, Ben-Gary|Maroni, Jaman|O'Donoghue, Kelley A|Chu, Karen W|Muscat, Jolene C|Pippo, Allison L|Wright, Connie E|Hollmann, Charleen|Wisnivesky, Juan P|Kessler, Paul D|Rasmussen, Henrik S|Rosengart, Todd K|Crystal, Ronald G
PMID: 11779412
Journal: Eur Arch Otorhinolaryngol. 2002 Apr;259(4):222-6.
Title: Reduction of neuronal and inducible nitric oxide synthase gene expression in patients with cystic fibrosis.
Author: Dotsch, Jorg|Puls, Jan|Klimek, Thorsten|Rascher, Wolfgang
PMID: 12064512
Journal: Mol Ther. 2002 Aug;6(2):287-97.
Title: Systemic interleukin-6 responses following administration of adenovirus gene transfer vectors to humans by different routes.
Author: Ben-Gary, Harvey|McKinney, Robin L|Rosengart, Todd|Lesser, Martin L|Crystal, Ronald G
PMID: 12349828
Journal: Cancer Biol Ther. 2003 Nov-Dec;2(6):652-5.
Title: Polymorphisms of SPINK1 N34S and CFTR in patients with sporadic and familial pancreatic cancer.
Author: Matsubayashi, Hiroyuki|Fukushima, Noriyoshi|Sato, Norihiro|Brune, Kieran|Canto, Marcia|Yeo, Charles J|Hruban, Ralph H|Kern, Scott E|Goggins, Michael
PMID: 14688470
Journal: Gastroenterology. 2008 Dec;135(6):2019-29.
Title: Transcriptional profiling of mRNA expression in the mouse distal colon.
Author: Hoogerwerf, Willemijntje A|Sinha, Mala|Conesa, Ana|Luxon, Bruce A|Shahinian, Vahakn B|Cornelissen, Germaine|Halberg, Franz|Bostwick, Jonathon|Timm, John|Cassone, Vincent M
PMID: 18848557
Journal: Dig Dis Sci. 2011 Feb;56(2):339-51.
Title: Lubiprostone activates Cl- secretion via cAMP signaling and increases membrane CFTR in the human colon carcinoma cell line, T84.
Author: Ao, Mei|Venkatasubramanian, Jayashree|Boonkaewwan, Chaiwat|Ganesan, Nivetha|Syed, Asma|Benya, Richard V|Rao, Mrinalini C
PMID: 21140215
Journal: Anal Biochem. 2011 Nov 15;418(2):231-7.
Title: Measurement of cystic fibrosis transmembrane conductance regulator activity using fluorescence spectrophotometry.
Author: Valdivieso, Angel G|Marin, Maria C|Clauzure, Mariangeles|Santa-Coloma, Tomas A
PMID: 21864494
Journal: Mutagenesis. 2012 Mar;27(2):187-96.
Title: The role of ABC transporters in progression and clinical outcome of colorectal cancer.
Author: Hlavata, I|Mohelnikova-Duchonova, B|Vaclavikova, R|Liska, V|Pitule, P|Novak, P|Bruha, J|Vycital, O|Holubec, L|Treska, V|Vodicka, P|Soucek, P
PMID: 22294766
Journal: PLoS One. 2012;7(11):e48059.
Title: The mitochondrial complex I activity is reduced in cells with impaired cystic fibrosis transmembrane conductance regulator (CFTR) function.
Author: Valdivieso, Angel G|Clauzure, Mariangeles|Marin, Maria C|Taminelli, Guillermo L|Massip Copiz, Maria M|Sanchez, Francisco|Schulman, Gustavo|Teiber, Maria L|Santa-Coloma, Tomas A
PMID: 23185247
Journal: Am J Physiol Cell Physiol. 2013 Aug 15;305(4):C447-56.
Title: Chenodeoxycholic acid stimulates Cl(-) secretion via cAMP signaling and increases cystic fibrosis transmembrane conductance regulator phosphorylation in T84 cells.
Author: Ao, Mei|Sarathy, Jayashree|Domingue, Jada|Alrefai, Waddah A|Rao, Mrinalini C
PMID: 23761628
Journal: PLoS One. 2014 Jun 5;9(6):e99257.
Title: Disruption of interleukin-1beta autocrine signaling rescues complex I activity and improves ROS levels in immortalized epithelial cells with impaired cystic fibrosis transmembrane conductance regulator (CFTR) function.
Author: Clauzure, Mariangeles|Valdivieso, Angel G|Massip Copiz, Maria M|Schulman, Gustavo|Teiber, Maria Luz|Santa-Coloma, Tomas A
PMID: 24901709
Journal: Biochim Biophys Acta. 2014 Mar;1843(3):618-28.
Title: Disrupted interaction between CFTR and AF-6/afadin aggravates malignant phenotypes of colon cancer.
Author: Sun, Ting Ting|Wang, Yan|Cheng, Hong|Xiao, Hu Zhang|Xiang, Juan Juan|Zhang, Jie Ting|Yu, Siu Bun Sydney|Martin, Tracey Amanda|Ye, Lin|Tsang, Lai Ling|Jiang, Wen Guo|Xiaohua, Jiang|Chan, Hsiao Chang
PMID: 24373847
Journal: Oncogene. 2014 Jul 17;33(29):3861-8.
Title: The role of KCNQ1 in mouse and human gastrointestinal cancers.
Author: Than, B L N|Goos, J A C M|Sarver, A L|O'Sullivan, M G|Rod, A|Starr, T K|Fijneman, R J A|Meijer, G A|Zhao, L|Zhang, Y|Largaespada, D A|Scott, P M|Cormier, R T
PMID: 23975432
Journal: J Biol Chem. 2015 May 1;290(18):11246-57.
Title: Compartmentalized accumulation of cAMP near complexes of multidrug resistance protein 4 (MRP4) and cystic fibrosis transmembrane conductance regulator (CFTR) contributes to drug-induced diarrhea.
Author: Moon, Changsuk|Zhang, Weiqiang|Ren, Aixia|Arora, Kavisha|Sinha, Chandrima|Yarlagadda, Sunitha|Woodrooffe, Koryse|Schuetz, John D|Valasani, Koteswara Rao|de Jonge, Hugo R|Shanmukhappa, Shiva Kumar|Shata, Mohamed Tarek M|Buddington, Randal K|Parthasarathi,
PMID: 25762723
Journal: Oncogene. 2016 Aug 11;35(32):4179-87.
Title: CFTR is a tumor suppressor gene in murine and human intestinal cancer.
Author: Than, B L N|Linnekamp, J F|Starr, T K|Largaespada, D A|Rod, A|Zhang, Y|Bruner, V|Abrahante, J|Schumann, A|Luczak, T|Walter, J|Niemczyk, A|O'Sullivan, M G|Medema, J P|Fijneman, R J A|Meijer, G A|Van den Broek, E|Hodges, C A|Scott, P M|Vermeulen, L|Cormier,
PMID: 26751771
Journal: World J Gastrointest Oncol. 2016 Mar 15;8(3):282-8.
Title: Emerging role of cystic fibrosis transmembrane conductance regulator - an epithelial chloride channel in gastrointestinal cancers.
Author: Hou, Yuning|Guan, Xiaoqing|Yang, Zhe|Li, Chunying
PMID: 26989463
Journal: Hum Genet. 2016 Jul;135(7):675-84.
Title: A review of gigaxonin mutations in giant axonal neuropathy (GAN) and cancer.
Author: Kang, James J|Liu, Isabelle Y|Wang, Marilene B|Srivatsan, Eri S
PMID: 27023907
Journal: Nutr Cancer. 2016 Nov-Dec;68(8):1338-1348.
Title: Sulforaphane Regulates NFE2L2/Nrf2-Dependent Xenobiotic Metabolism Phase II and Phase III Enzymes Differently in Human Colorectal Cancer and Untransformed Epithelial Colon Cells.
Author: Lubelska, Katarzyna|Wiktorska, Katarzyna|Mielczarek, Lidia|Milczarek, Malgorzata|Zbroinska-Bregisz, Ilona|Chilmonczyk, Zdzislaw
PMID: 27636860
Journal: Arab J Gastroenterol. 2017 Dec;18(4):191-200.
Title: Simple classifiers for molecular subtypes of colorectal cancer.
Author: Kim, Woo Gyeong|Kim, Joo Yeon|Park, Do Youn
PMID: 29241727
Journal: Gene. 2018 Sep 25;672:64-71.
Title: The detection and significance of cystic fibrosis transmembrane conductance regulator gene promoter mutations in Chinese patients with congenital bilateral absence of the vas deferens.
Author: Bai, Song|Du, Qiang|Liu, Xiaoliang|Tong, Yuxin|Wu, Bin
PMID: 29864494
Journal: Mol Oncol. 2018 Sep;12(9):1639-1655.
Title: Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer.
Author: Bruun, Jarle|Sveen, Anita|Barros, Rita|Eide, Peter W|Eilertsen, Ina|Kolberg, Matthias|Pellinen, Teijo|David, Leonor|Svindland, Aud|Kallioniemi, Olli|Guren, Marianne G|Nesbakken, Arild|Almeida, Raquel|Lothe, Ragnhild A
PMID: 29900672