Primary Site >> Colorectal Cancer
Gene >> CFTR
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Ref: Expression of the cystic fibrosis transmembrane conductance regulator gene in cells of non-epithelial origin. PMID: 1717947 |
Ref: Biochemical characterization of the cystic fibrosis transmembrane conductance regulator in normal and cystic fibrosis epithelial cells. PMID: 1370488 Ref: Down-regulation of cystic fibrosis transmembrane conductance regulator gene expression by agents that modulate intracellular divalent cations. PMID: 1372390 Ref: A1 adenosine-receptor antagonists activate chloride efflux from cystic fibrosis cells. PMID: 1376923 Ref: Expression of the cystic fibrosis transmembrane conductance regulator gene can be regulated by protein kinase C. PMID: 1379589 |
Ref: Transfer of a constitutive viral promoter-cystic fibrosis transmembrane conductance regulator cDNA to human epithelial cells conveys resistance to down-regulation of cAMP-regulated Cl- secretion in the presence of inflammatory stimuli. PMID: 7526342 |
Ref: Endogenous expression of type II cGMP-dependent protein kinase mRNA and protein in rat intestine. Implications for cystic fibrosis transmembrane conductance regulator. PMID: 7543493 Ref: Basal expression of the cystic fibrosis transmembrane conductance regulator gene is dependent on protein kinase A activity. PMID: 7543684 |
Ref: Identification by differential display of a mRNA specifically induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in T84 human colon carcinoma cells. PMID: 8832110 Ref: Characterization of the cAMP response element of the cystic fibrosis transmembrane conductance regulator gene promoter. PMID: 8943230 |
Ref: Interrelationship between the Na+/glucose cotransporter and CFTR in Caco-2 cells: relevance to cystic fibrosis. PMID: 9699500 |
Ref: CFTR expression does not influence glycosylation of an epitope-tagged MUC1 mucin in colon carcinoma cell lines. PMID: 10089213 |
Ref: Uroguanylin treatment suppresses polyp formation in the Apc(Min/+) mouse and induces apoptosis in human colon adenocarcinoma cells via cyclic GMP. PMID: 11016642 |
Ref: An element in intron 1 of the CFTR gene augments intestinal expression in vivo. PMID: 11448937 |
Ref: Electrolyte transport in the mammalian colon: mechanisms and implications for disease. PMID: 11773614 Ref: Safety of local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of morbid conditions. PMID: 11779412 Ref: Reduction of neuronal and inducible nitric oxide synthase gene expression in patients with cystic fibrosis. PMID: 12064512 Ref: Systemic interleukin-6 responses following administration of adenovirus gene transfer vectors to humans by different routes. PMID: 12349828 |
Ref: Polymorphisms of SPINK1 N34S and CFTR in patients with sporadic and familial pancreatic cancer. PMID: 14688470 |
Ref: Transcriptional profiling of mRNA expression in the mouse distal colon. PMID: 18848557 |
Ref: Lubiprostone activates Cl- secretion via cAMP signaling and increases membrane CFTR in the human colon carcinoma cell line, T84. PMID: 21140215 Ref: Measurement of cystic fibrosis transmembrane conductance regulator activity using fluorescence spectrophotometry. PMID: 21864494 |
Ref: The role of ABC transporters in progression and clinical outcome of colorectal cancer. PMID: 22294766 Ref: The mitochondrial complex I activity is reduced in cells with impaired cystic fibrosis transmembrane conductance regulator (CFTR) function. PMID: 23185247 |
Ref: Chenodeoxycholic acid stimulates Cl(-) secretion via cAMP signaling and increases cystic fibrosis transmembrane conductance regulator phosphorylation in T84 cells. PMID: 23761628 |
Ref: The role of KCNQ1 in mouse and human gastrointestinal cancers. PMID: 23975432 Ref: Disrupted interaction between CFTR and AF-6/afadin aggravates malignant phenotypes of colon cancer. PMID: 24373847 Ref: Disruption of interleukin-1beta autocrine signaling rescues complex I activity and improves ROS levels in immortalized epithelial cells with impaired cystic fibrosis transmembrane conductance regulator (CFTR) function. PMID: 24901709 |
Ref: Compartmentalized accumulation of cAMP near complexes of multidrug resistance protein 4 (MRP4) and cystic fibrosis transmembrane conductance regulator (CFTR) contributes to drug-induced diarrhea. PMID: 25762723 |
Ref: CFTR is a tumor suppressor gene in murine and human intestinal cancer. PMID: 26751771 Ref: Emerging role of cystic fibrosis transmembrane conductance regulator - an epithelial chloride channel in gastrointestinal cancers. PMID: 26989463 Ref: A review of gigaxonin mutations in giant axonal neuropathy (GAN) and cancer. PMID: 27023907 Ref: Sulforaphane Regulates NFE2L2/Nrf2-Dependent Xenobiotic Metabolism Phase II and Phase III Enzymes Differently in Human Colorectal Cancer and Untransformed Epithelial Colon Cells. PMID: 27636860 |
Ref: Simple classifiers for molecular subtypes of colorectal cancer. PMID: 29241727 |
Ref: The detection and significance of cystic fibrosis transmembrane conductance regulator gene promoter mutations in Chinese patients with congenital bilateral absence of the vas deferens. PMID: 29864494 Ref: Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer. PMID: 29900672 |