Literatures

Primary Site >> Colorectal Cancer

Gene >> CFLAR

1.
Journal:	Scand J Work Environ Health. 1983 Aug;9(4):315-26.
Title:	Nasal and sinonasal cancer. Connection with occupational exposures in Denmark, Finland and Sweden.
Author:	Hernberg, S\|Westerholm, P\|Schultz-Larsen, K\|Degerth, R\|Kuosma, E\|Englund, A\|Engzell, U\|Hansen, H S\|Mutanen, P
PMID:	6635610

2.
Journal:	Gan To Kagaku Ryoho. 1990 Mar;17(3 Pt 2):524-31.
Title:	[Methodological aspects on the histological evaluation of subrenal capsule assay (SRCA)].
Author:	Yamada, H
PMID:	2108610

3.
Journal:	J Gastrointest Surg. 2001 Jan-Feb;5(1):56-65.
Title:	Sensitization of human colon cancer cells to TRAIL-mediated apoptosis.
Author:	Hernandez, A\|Wang, Q D\|Schwartz, S A\|Evers, B M
PMID:	11309649

4.
Journal:	Biol Trace Elem Res. 2001 Feb;79(2):107-14.
Title:	Serum levels of selenium, manganese, copper, and iron in colorectal cancer patients.
Author:	Milde, D\|Novak, O\|Stu ka, V\|Vyslou il, K\|Macha ek, J
PMID:	11330516

5.
Journal:	J Biol Chem. 2001 Oct 12;276(41):37879-86.
Title:	Identification of inhibitors of TRAIL-induced death (ITIDs) in the TRAIL-sensitive colon carcinoma cell line SW480 using a genetic approach.
Author:	Burns, T F\|El-Deiry, W S
PMID:	11486001

6.
Journal:	Surgery. 2001 Aug;130(2):265-72.
Title:	Butyrate sensitizes human colon cancer cells to TRAIL-mediated apoptosis.
Author:	Hernandez, A\|Thomas, R\|Smith, F\|Sandberg, J\|Kim, S\|Chung, D H\|Evers, B M
PMID:	11490359

7.
Journal:	Oncogene. 2001 Aug 23;20(37):5225-31.
Title:	Accelerated degradation of cellular FLIP protein through the ubiquitin-proteasome pathway in p53-mediated apoptosis of human cancer cells.
Author:	Fukazawa, T\|Fujiwara, T\|Uno, F\|Teraishi, F\|Kadowaki, Y\|Itoshima, T\|Takata, Y\|Kagawa, S\|Roth, J A\|Tschopp, J\|Tanaka, N
PMID:	11526513

8.
Journal:	Oncogene. 2002 Jan 17;21(3):337-46.
Title:	Low glucose-enhanced TRAIL cytotoxicity is mediated through the ceramide-Akt-FLIP pathway.
Author:	Nam, Seon Young\|Amoscato, Andrew A\|Lee, Yong J
PMID:	11821946

9.
Journal:	Gene Ther. 2002 Sep;9(18):1262-70.
Title:	Mechanisms involved in development of resistance to adenovirus-mediated proapoptotic gene therapy in DLD1 human colon cancer cell line.
Author:	Zhang, L\|Gu, J\|Lin, T\|Huang, X\|Roth, J A\|Fang, B
PMID:	12215894

10.
Journal:	Neoplasia. 2002 Nov-Dec;4(6):551-7.
Title:	Defining characteristics of Types I and II apoptotic cells in response to TRAIL.
Author:	Ozoren, Nesrin\|El-Deiry, Wafik S
PMID:	12407450

11.
Journal:	Br J Cancer. 2003 Mar 10;88(5):788-95.
Title:	Endothelin-receptor antagonists are proapoptotic and antiproliferative in human colon cancer cells.
Author:	Peduto Eberl, L\|Bovey, R\|Juillerat-Jeanneret, L
PMID:	12618891

12.
Journal:	Oncogene. 2003 Aug 7;22(32):4953-63.
Title:	The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells.
Author:	Johnson, Thomas R\|Stone, Kimberley\|Nikrad, Malti\|Yeh, Tammie\|Zong, Wei-Xing\|Thompson, Craig B\|Nesterov, Alexandre\|Kraft, Andrew S
PMID:	12902978

13.
Journal:	Exp Cell Res. 2004 Feb 1;293(1):129-43.
Title:	Low extracellular pH augments TRAIL-induced apoptotic death through the mitochondria-mediated caspase signal transduction pathway.
Author:	Lee, Yong J\|Song, Jae J\|Kim, Jin H\|Kim, Hyeong-Reh Choi\|Song, Young K
PMID:	14729063

14.
Journal:	Drug Resist Updat. 2004 Dec;7(6):345-58.
Title:	Lessons from TRAIL-resistance mechanisms in colorectal cancer cells: paving the road to patient-tailored therapy.
Author:	Van Geelen, Caroline M M\|de Vries, Elisabeth G E\|de Jong, Steven
PMID:	15790545

15.
Journal:	Oncogene. 2004 Sep 16;23(42):7067-75.
Title:	Regulation of caspase-6 and FLIP by the AMPK family member ARK5.
Author:	Suzuki, Atsushi\|Kusakai, Gen-Ichi\|Kishimoto, Atsuhiro\|Shimojo, Yosuke\|Miyamoto, Sinichi\|Ogura, Tsutomu\|Ochiai, Atsushi\|Esumi, Hiroyasu
PMID:	15273717

16.
Journal:	Carcinogenesis. 2005 Mar;26(3):637-42.
Title:	Meat intake, cooking-related mutagens and risk of colorectal adenoma in a sigmoidoscopy-based case-control study.
Author:	Gunter, Marc J\|Probst-Hensch, Nicole M\|Cortessis, Victoria K\|Kulldorff, Martin\|Haile, Robert W\|Sinha, Rashmi
PMID:	15579480

17.
Journal:	World J Gastroenterol. 2005 Apr 28;11(16):2482-5.
Title:	Expression of cellular FLICE-inhibitory protein and its association with p53 mutation in colon cancer.
Author:	Zhou, Xiao-Dong\|Yu, Jie-Ping\|Chen, Hong-Xia\|Yu, Hong-Gang\|Luo, He-Sheng
PMID:	15832422

18.
Journal:	J Physiol Pharmacol. 2005 Jun;56 Suppl 3:101-18.
Title:	Cycloheximide-mediated sensitization to TNF-alpha-induced apoptosis in human colorectal cancer cell line COLO 205; role of FLIP and metabolic inhibitors.
Author:	Pajak, B\|Gajkowska, B\|Orzechowski, A
PMID:	16077198

19.
Journal:	Cancer Biol Ther. 2005 Jul;4(7):781-6. Epub 2005 Jul 6.
Title:	Proteasome inhibitors-mediated TRAIL resensitization and Bik accumulation.
Author:	Zhu, Hongbo\|Guo, Wei\|Zhang, Lidong\|Wu, Shuhong\|Teraishi, Fuminori\|Davis, John J\|Dong, Fengqin\|Fang, Bingliang
PMID:	16082182

20.
Journal:	Cell Cycle. 2005 Sep;4(9):1201-15.
Title:	Molecular targets and anticancer potential of indole-3-carbinol and its derivatives.
Author:	Aggarwal, Bharat B\|Ichikawa, Haruyo
PMID:	16082211

21.
Journal:	Mol Cancer Ther. 2005 Dec;4(12):2026-36.
Title:	Chemotherapy and TRAIL-mediated colon cancer cell death: the roles of p53, TRAIL receptors, and c-FLIP.
Author:	Galligan, Leeona\|Longley, Daniel B\|McEwan, Miranda\|Wilson, Timothy R\|McLaughlin, Kirsty\|Johnston, Patrick G
PMID:	16373718

22.
Journal:	Apoptosis. 2006 Sep;11(9):1617-28.
Title:	Zebrafish embryo proteins induce apoptosis in human colon cancer cells (Caco2).
Author:	Cucina, Alessandra\|Biava, Pier-Mario\|D'Anselmi, Fabrizio\|Coluccia, Pierpaolo\|Conti, Filippo\|di Clemente, Roberta\|Miccheli, Alfredo\|Frati, Luigi\|Gulino, Alberto\|Bizzarri, Mariano
PMID:	16820966

23.
Journal:	Adv Med Sci. 2006;51:39-45.
Title:	Overview how adenocarcinoma cancer cells avoid immune- and chemotherapy-induced apoptosis.
Author:	Pajak, B\|Orzechowski, A
PMID:	17357275

24.
Journal:	Cancer Res. 2006 Dec 1;66(23):11115-9.
Title:	Cellular FLICE-inhibitory protein down-regulation contributes to celecoxib-induced apoptosis in human lung cancer cells.
Author:	Liu, Xiangguo\|Yue, Ping\|Schonthal, Axel H\|Khuri, Fadlo R\|Sun, Shi-Yong
PMID:	17145853

25.
Journal:	Biol Reprod. 2006 Mar;74(3):560-8. Epub 2005 Nov 23.
Title:	Influence of TRP53 status on FAS membrane localization, CFLAR (c-FLIP) ubiquitinylation, and sensitivity of GC-2spd (ts) cells to undergo FAS-mediated apoptosis.
Author:	Chandrasekaran, Yamini\|McKee, Chad M\|Ye, Yang\|Richburg, John H
PMID:	16306425

26.
Journal:	Oncogene. 2006 Feb 9;25(6):838-48.
Title:	c-FLIP inhibits chemotherapy-induced colorectal cancer cell death.
Author:	Longley, D B\|Wilson, T R\|McEwan, M\|Allen, W L\|McDermott, U\|Galligan, L\|Johnston, P G
PMID:	16247474

27.
Journal:	Int J Cancer. 2006 Jan 15;118(2):326-34.
Title:	PKCdelta-mediated regulation of FLIP expression in human colon cancer cells.
Author:	Wang, Qingding\|Wang, Xiaofu\|Zhou, Yuning\|Evers, B Mark
PMID:	16052516

28.
Journal:	Apoptosis. 2007 Aug;12(8):1465-78.
Title:	Expression of anti-apoptotic factors modulates Apo2L/TRAIL resistance in colon carcinoma cells.
Author:	Lippa, Mara S\|Strockbine, Laura D\|Le, Tiep T\|Branstetter, Daniel G\|Strathdee, Craig A\|Holland, Pamela M
PMID:	17440816

29.
Journal:	Histopathology. 2007 Aug;51(2):150-6. Epub 2007 Jun 8.
Title:	c-FLIP expression in colorectal carcinomas: association with Fas/FasL expression and prognostic implications.
Author:	Korkolopoulou, P\|Saetta, A A\|Levidou, G\|Gigelou, F\|Lazaris, A\|Thymara, I\|Scliri, M\|Bousboukea, K\|Michalopoulos, N V\|Apostolikas, N\|Konstantinidou, A\|Tzivras, M\|Patsouris, E
PMID:	17559541

30.
Journal:	Cancer Res. 2007 Jun 15;67(12):5754-62.
Title:	c-FLIP: a key regulator of colorectal cancer cell death.
Author:	Wilson, Timothy R\|McLaughlin, Kirsty M\|McEwan, Miranda\|Sakai, Hidekazu\|Rogers, Katherine M A\|Redmond, Kelly M\|Johnston, Patrick G\|Longley, Daniel B
PMID:	17575142

31.
Journal:	Mol Pharmacol. 2007 Sep;72(3):704-14. Epub 2007 Jun 19.
Title:	Low-dose BBR3610 toxicity in colon cancer cells is p53-independent and enhanced by inhibition of epidermal growth factor receptor (ERBB1)-phosphatidyl inositol 3 kinase signaling.
Author:	Mitchell, Clint\|Kabolizadeh, Peyman\|Ryan, John\|Roberts, John D\|Yacoub, Adly\|Curiel, David T\|Fisher, Paul B\|Hagan, Michael P\|Farrell, Nicholas P\|Grant, Steven\|Dent, Paul
PMID:	17578896

32.
Journal:	J Surg Res. 2007 Sep;142(1):184-94. Epub 2007 Jul 2.
Title:	Modification of gene products involved in resistance to apoptosis in metastatic colon cancer cells: roles of Fas, Apaf-1, NFkappaB, IAPs, Smac/DIABLO, and AIF.
Author:	Huerta, Sergio\|Heinzerling, John H\|Anguiano-Hernandez, Yu-Mei\|Huerta-Yepez, Sara\|Lin, Jeffrey\|Chen, David\|Bonavida, Benjamin\|Livingston, Edward H
PMID:	17603079

33.
Journal:	Clin Cancer Res. 2007 Sep 1;13(17):5070-5.
Title:	Overexpression of FLIPL is an independent marker of poor prognosis in colorectal cancer patients.
Author:	Ullenhag, Gustave J\|Mukherjee, Abhik\|Watson, Nicholas F S\|Al-Attar, Ahmad H\|Scholefield, John H\|Durrant, Lindy G
PMID:	17785559

34.
Journal:	Pol J Vet Sci. 2007;10(2):127-30.
Title:	Antiapoptotic proteins as targets for bioactive compounds.
Author:	Pajak, B
PMID:	17882939

35.
Journal:	J Physiol Pharmacol. 2007 Aug;58 Suppl 3:163-76.
Title:	Sodium butyrate-dependent sensitization of human colon adenocarcinoma COLO 205 cells to TNF-alpha-induced apoptosis.
Author:	Pajak, B\|Orzechowski, A
PMID:	17901592

36.
Journal:	Verh Dtsch Ges Pathol. 2007;91:294-301.
Title:	[The anti-diabetic drug troglitazone sensitizes colon cancer cells to TRAIL-induced apoptosis by down-regulating FLIP].
Author:	Roth, W\|Grund, K\|Wiestler, O D\|Schirmacher, P
PMID:	18314627

37.
Journal:	Oncol Rep. 2008 Feb;19(2):567-73.
Title:	Response of normal and colon cancer epithelial cells to TNF-family apoptotic inducers.
Author:	Hofmanova, Jirina\|Vaculova, Alena\|Hyzd'alova, Martina\|Kozubik, Alois
PMID:	18202809

38.
Journal:	Int J Cancer. 2008 Aug 15;123(4):951-7.
Title:	Simvastatin induces apoptosis in human colon cancer cells and in tumor xenografts, and attenuates colitis-associated colon cancer in mice.
Author:	Cho, Soo-Jeong\|Kim, Joo Sung\|Kim, Jung Mogg\|Lee, Jong Yeul\|Jung, Hyun Chae\|Song, In Sung
PMID:	18521906

39.
Journal:	Cell Biol Int. 2008 Mar;32(3):329-36.
Title:	Critical role for c-FLIP(L) on Fas resistance in colon carcinoma cell line HT-29.
Author:	Zang, Fenglin\|Sun, Baocun\|Zhao, Xiulan\|Niu, Ruifang\|Zhang, Shiwu\|Yu, Man\|Wei, Xiyin\|Zhang, Lin
PMID:	18243739

40.
Journal:	Oncogene. 2009 Jan 8;28(1):63-72.
Title:	Combined inhibition of FLIP and XIAP induces Bax-independent apoptosis in type II colorectal cancer cells.
Author:	Wilson, T R\|McEwan, M\|McLaughlin, K\|Le Clorennec, C\|Allen, W L\|Fennell, D A\|Johnston, P G\|Longley, D B
PMID:	18820704

41.
Journal:	Apoptosis. 2009 Feb;14(2):203-17.
Title:	Sodium butyrate sensitizes human colon adenocarcinoma COLO 205 cells to both intrinsic and TNF-alpha-dependent extrinsic apoptosis.
Author:	Pajak, Beata\|Gajkowska, Barbara\|Orzechowski, Arkadiusz
PMID:	19130237

42.
Journal:	J Theor Biol. 2009 Apr 21;257(4):598-608.
Title:	A mathematical model of doxorubicin penetration through multicellular layers.
Author:	Evans, C J\|Phillips, R M\|Jones, P F\|Loadman, P M\|Sleeman, B D\|Twelves, C J\|Smye, S W
PMID:	19183560

43.
Journal:	Mol Pharmacol. 2009 Jul;76(1):192-200.
Title:	S-Adenosylmethionine and methylthioadenosine inhibit cellular FLICE inhibitory protein expression and induce apoptosis in colon cancer cells.
Author:	Li, Tony W H\|Zhang, Qingsong\|Oh, Pilsoo\|Xia, Meng\|Chen, Hui\|Bemanian, Sean\|Lastra, Natalie\|Circ, Magda\|Moyer, Mary Pat\|Mato, Jose M\|Aw, Tak Yee\|Lu, Shelly C
PMID:	19372210

44.
Journal:	Mol Pharmacol. 2009 Aug;76(2):342-55.
Title:	Sorafenib and vorinostat kill colon cancer cells by CD95-dependent and -independent mechanisms.
Author:	Walker, Teneille\|Mitchell, Clint\|Park, Margaret A\|Yacoub, Adly\|Graf, Martin\|Rahmani, Mohamed\|Houghton, Peter J\|Voelkel-Johnson, Christina\|Grant, Steven\|Dent, Paul
PMID:	19483104

45.
Journal:	Cancer Prev Res (Phila). 2009 Aug;2(8):732-42.
Title:	Regulation of colorectal cancer cell apoptosis by the n-3 polyunsaturated fatty acids Docosahexaenoic and Eicosapentaenoic.
Author:	Giros, Anna\|Grzybowski, Mike\|Sohn, Vanessa R\|Pons, Elisenda\|Fernandez-Morales, Jessica\|Xicola, Rosa M\|Sethi, Puja\|Grzybowski, Jessica\|Goel, Ajay\|Boland, C Richard\|Gassull, Miquel A\|Llor, Xavier
PMID:	19638488

46.
Journal:	J Biol Chem. 2010 Nov 12;285(46):35418-27.
Title:	Gossypol induces death receptor-5 through activation of the ROS-ERK-CHOP pathway and sensitizes colon cancer cells to TRAIL.
Author:	Sung, Bokyung\|Ravindran, Jayaraj\|Prasad, Sahdeo\|Pandey, Manoj K\|Aggarwal, Bharat B
PMID:	20837473

47.
Journal:	Int J Oncol. 2010 Oct;37(4):1031-41.
Title:	Downregulation of active caspase 8 as a mechanism of acquired TRAIL resistance in mismatch repair-proficient colon carcinoma cell lines.
Author:	Van Geelen, Caroline M M\|Pennarun, Bodvael\|Ek, Wytske Boerma-Van\|Le, Phuong T K\|Spierings, Diana C J\|De Vries, Elisabeth G E\|De Jong, Steven
PMID:	20811726

48.
Journal:	Br J Cancer. 2010 Feb 16;102(4):754-64.
Title:	Early growth response-1 is a regulator of DR5-induced apoptosis in colon cancer cells.
Author:	Mahalingam, D\|Natoni, A\|Keane, M\|Samali, A\|Szegezdi, E
PMID:	20087343

49.
Journal:	Clin Cancer Res. 2010 Jul 1;16(13):3442-51.
Title:	Prognostic significance of TRAIL signaling molecules in stage II and III colorectal cancer.
Author:	McLornan, Donal P\|Barrett, Helen L\|Cummins, Robert\|McDermott, Ultan\|McDowell, Cliona\|Conlon, Susie J\|Coyle, Victoria M\|Van Schaeybroeck, Sandra\|Wilson, Richard\|Kay, Elaine W\|Longley, Daniel B\|Johnston, Patrick G
PMID:	20570920

50.
Journal:	Cancer Lett. 2010 Jul 28;293(2):158-66.
Title:	Synergistic antitumor effect of TRAIL in combination with sunitinib in vitro and in vivo.
Author:	Ding, Wanjing\|Cai, Tianyu\|Zhu, Hong\|Wu, Rui\|Tu, Chongxing\|Yang, Liuqing\|Lu, Wei\|He, Qiaojun\|Yang, Bo
PMID:	20137855

51.
Journal:	J Biol Chem. 2010 Jun 18;285(25):19162-72.
Title:	Inhibition of NF-kappaB signaling by quinacrine is cytotoxic to human colon carcinoma cell lines and is synergistic in combination with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) or oxaliplatin.
Author:	Jani, Tanvi S\|DeVecchio, Jennifer\|Mazumdar, Tapati\|Agyeman, Akwasi\|Houghton, Janet A
PMID:	20424169

52.
Journal:	Cancer Lett. 2010 Jan 1;287(1):98-108.
Title:	Nutlin-3 enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through up-regulation of death receptor 5 (DR5) in human sarcoma HOS cells and human colon cancer HCT116 cells.
Author:	Hori, Takeshi\|Kondo, Takashi\|Kanamori, Masahiko\|Tabuchi, Yoshiaki\|Ogawa, Ryohei\|Zhao, Qing-Li\|Ahmed, Kanwal\|Yasuda, Taketoshi\|Seki, Shoji\|Suzuki, Kayo\|Kimura, Tomoatsu
PMID:	19577358

53.
Journal:	Cell Death Differ. 2010 Mar;17(3):551-61.
Title:	Radiation and anticancer drugs can facilitate mitochondrial bypass by CD95/Fas via c-FLIP downregulation.
Author:	Verbrugge, I\|Maas, C\|Heijkoop, M\|Verheij, M\|Borst, J
PMID:	19798106

54.
Journal:	Oncol Rep. 2011 Feb;25(2):419-24.
Title:	Death receptor 5-mediated TNFR family signaling pathways modulate gamma-humulene-induced apoptosis in human colorectal cancer HT29 cells.
Author:	Lan, Yu-Hsuan\|Wu, Yang-Chang\|Wu, Kai-Wei\|Chung, Jing-Gung\|Lu, Chi-Cheng\|Chen, Yuan-Liang\|Wu, Tian-Shung\|Yang, Jai-Sing
PMID:	21152878

55.
Journal:	Fam Cancer. 2011 Jun;10(2):245-54.
Title:	Linkage to chromosome 2q32.2-q33.3 in familial serrated neoplasia (Jass syndrome).
Author:	Roberts, Aedan\|Nancarrow, Derek\|Clendenning, Mark\|Buchanan, Daniel D\|Jenkins, Mark A\|Duggan, David\|Taverna, Darin\|McKeone, Diane\|Walters, Rhiannon\|Walsh, Michael D\|Young, Bruce W\|Jass, Jeremy R\|Rosty, Christophe\|Gattas, Michael\|Pelzer, Elise\|Hopper, John
PMID:	21165777

56.
Journal:	Pathologe. 2011 Jul;32(4):330-5.
Title:	[Steatohepatitis after chemotherapy for colorectal liver metastases (CASH)].
Author:	Tannapfel, A\|Reinacher-Schick, A\|Flott-Rahmel, B
PMID:	21681471

57.
Journal:	Cancer Res. 2011 Oct 1;71(19):6270-81.
Title:	Celecoxib promotes c-FLIP degradation through Akt-independent inhibition of GSK3.
Author:	Chen, Shuzhen\|Cao, Wei\|Yue, Ping\|Hao, Chunhai\|Khuri, Fadlo R\|Sun, Shi-Yong
PMID:	21868755

58.
Journal:	Cell Death Differ. 2012 Aug;19(8):1317-27.
Title:	Identification of an acetylation-dependant Ku70/FLIP complex that regulates FLIP expression and HDAC inhibitor-induced apoptosis.
Author:	Kerr, E\|Holohan, C\|McLaughlin, K M\|Majkut, J\|Dolan, S\|Redmond, K\|Riley, J\|McLaughlin, K\|Stasik, I\|Crudden, M\|Van Schaeybroeck, S\|Fenning, C\|O'Connor, R\|Kiely, P\|Sgobba, M\|Haigh, D\|Johnston, P G\|Longley, D B
PMID:	22322857

59.
Journal:	Clin Cancer Res. 2012 Oct 1;18(19):5412-26.
Title:	Identification of galanin and its receptor GalR1 as novel determinants of resistance to chemotherapy and potential biomarkers in colorectal cancer.
Author:	Stevenson, Leanne\|Allen, Wendy L\|Turkington, Richard\|Jithesh, Puthen V\|Proutski, Irina\|Stewart, Gail\|Lenz, Heinz-Josef\|Van Schaeybroeck, Sandra\|Longley, Daniel B\|Johnston, Patrick G
PMID:	22859720

60.
Journal:	PLoS One. 2012;7(2):e31762.
Title:	Sub-lethal irradiation of human colorectal tumor cells imparts enhanced and sustained susceptibility to multiple death receptor signaling pathways.
Author:	Ifeadi, Victoria\|Garnett-Benson, Charlie
PMID:	22389673

61.
Journal:	J Biol Chem. 2012 Jan 2;287(1):641-9.
Title:	Wogonin and related natural flavones overcome tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein resistance of tumors by down-regulation of c-FLIP protein and up-regulation of TRAIL receptor 2 expression.
Author:	Ding, Jie\|Polier, Gernot\|Kohler, Rebecca\|Giaisi, Marco\|Krammer, Peter H\|Li-Weber, Min
PMID:	22086925

62.
Journal:	Mol Cancer Ther. 2012 Jan;11(1):119-31.
Title:	A systems biology approach identifies SART1 as a novel determinant of both 5-fluorouracil and SN38 drug resistance in colorectal cancer.
Author:	Allen, Wendy L\|Stevenson, Leanne\|Coyle, Vicky M\|Jithesh, Puthen V\|Proutski, Irina\|Carson, Gail\|Gordon, Michael A\|Lenz, Heinz-Josef D\|Van Schaeybroeck, Sandra\|Longley, Daniel B\|Johnston, Patrick G
PMID:	22027693

63.
Journal:	Br J Nutr. 2012 Jun;107(11):1591-602.
Title:	Stool-fermented Plantago ovata husk induces apoptosis in colorectal cancer cells independently of molecular phenotype.
Author:	Sohn, Vanessa R\|Giros, Anna\|Xicola, Rosa M\|Fluvia, Lourdes\|Grzybowski, Mike\|Anguera, Anna\|Llor, Xavier
PMID:	22018732

64.
Journal:	Int J Cancer. 2012 Apr 1;130(7):1494-503.
Title:	Pharmacologic downregulation of c-FLIP(L) restores juxtacrine death receptor-mediated apoptosis in cancer cells in a peritoneal carcinomatosis model.
Author:	Shen, Yi\|Herde, Ryan\|Doxey, Brett W\|Xu, Changxin\|Gray, Phillip D\|Kuwada, Scott K
PMID:	21480219

65.
Journal:	Rheumatol Int. 2012 Apr;32(4):1087-9.
Title:	Systemic lupus erythematosus associated with Wells' syndrome.
Author:	Yin, Geng\|Xie, Qibing
PMID:	21340570

66.
Journal:	J Pathol. 2013 Feb;229(3):410-21.
Title:	Targeting FLIP and Mcl-1 using a combination of aspirin and sorafenib sensitizes colon cancer cells to TRAIL.
Author:	Pennarun, Bodvael\|Kleibeuker, Jan H\|Boersma-van Ek, Wytske\|Kruyt, Frank A E\|Hollema, Harry\|de Vries, Elisabeth G E\|de Jong, Steven
PMID:	23132258

67.
Journal:	Apoptosis. 2013 Jun;18(6):739-50.
Title:	The plant alkaloid and anti-leukemia drug homoharringtonine sensitizes resistant human colorectal carcinoma cells to TRAIL-induced apoptosis via multiple mechanisms.
Author:	Beranova, Lenka\|Pombinho, Antonio R\|Spegarova, Jarmila\|Koc, Michal\|Klanova, Magdalena\|Molinsky, Jan\|Klener, Pavel\|Bartunek, Petr\|Andera, Ladislav
PMID:	23456623

68.
Journal:	Cell Death Dis. 2013 Apr 4;4:e577.
Title:	Hyperthermia enhances mapatumumab-induced apoptotic death through ubiquitin-mediated degradation of cellular FLIP(long) in human colon cancer cells.
Author:	Song, X\|Kim, S-Y\|Zhou, Z\|Lagasse, E\|Kwon, Y T\|Lee, Y J
PMID:	23559011

69.
Journal:	Free Radic Biol Med. 2013 Oct;63:280-90.
Title:	Aldose reductase inhibition enhances TRAIL-induced human colon cancer cell apoptosis through AKT/FOXO3a-dependent upregulation of death receptors.
Author:	Shoeb, Mohammad\|Ramana, Kota V\|Srivastava, Satish K
PMID:	23732517

70.
Journal:	Cancer Sci. 2013 Dec;104(12):1632-9.
Title:	Amurensin G enhances the susceptibility to tumor necrosis factor-related apoptosis-inducing ligand-mediated cytotoxicity of cancer stem-like cells of HCT-15 cells.
Author:	Lee, Su-Hoon\|Kim, Mi-Ju\|Kim, Dong-Wan\|Kang, Chi-Dug\|Kim, Sun-Hee
PMID:	24118446

71.
Journal:	Cancer Biol Ther. 2014;15(12):1646-57.
Title:	Regulation of dimethyl-fumarate toxicity by proteasome inhibitors.
Author:	Booth, Laurence\|Cruickshanks, Nichola\|Tavallai, Seyedmehrad\|Roberts, Jane L\|Peery, Matthew\|Poklepovic, Andrew\|Dent, Paul
PMID:	25482938

72.
Journal:	Cell Death Dis. 2014 Feb 6;5:e1046.
Title:	Fibroblast growth factor receptor 4 (FGFR4): a targetable regulator of drug resistance in colorectal cancer.
Author:	Turkington, R C\|Longley, D B\|Allen, W L\|Stevenson, L\|McLaughlin, K\|Dunne, P D\|Blayney, J K\|Salto-Tellez, M\|Van Schaeybroeck, S\|Johnston, P G
PMID:	24503538

73.
Journal:	J Surg Oncol. 2014 Mar;109(3):255-65.
Title:	Expression of apoptosis regulating proteins identifies stage II and III colon cancer patients with high risk of recurrence.
Author:	Belt, Eric J Th\|Stockmann, Hein B A C\|Delis-van Diemen, Pien M\|Bril, Herman\|Tijssen, Marianne\|van Essen, Hendrik F\|Heymans, Martijn W\|Belien, Jeroen A M\|Carvalho, Beatriz\|Cillessen, Saskia A G M\|Meijer, Gerrit A
PMID:	24249458

74.
Journal:	Mol Ther. 2014 Dec;22(12):2083-92.
Title:	Efficient drug delivery and induction of apoptosis in colorectal tumors using a death receptor 5-targeted nanomedicine.
Author:	Schmid, Daniela\|Fay, Francois\|Small, Donna M\|Jaworski, Jakub\|Riley, Joel S\|Tegazzini, Diana\|Fenning, Cathy\|Jones, David S\|Johnston, Patrick G\|Longley, Daniel B\|Scott, Christopher J
PMID:	25200008

75.
Journal:	Clin Cancer Res. 2015 Jul 15;21(14):3230-3240.
Title:	HDAC Inhibition Overcomes Acute Resistance to MEK Inhibition in BRAF-Mutant Colorectal Cancer by Downregulation of c-FLIPL.
Author:	Carson, Robbie\|Celtikci, Basak\|Fenning, Cathy\|Javadi, Arman\|Crawford, Nyree\|Carbonell, Lucia Perez\|Lawler, Mark\|Longley, Daniel B\|Johnston, Patrick G\|Van Schaeybroeck, Sandra
PMID:	25813020

76.
Journal:	Mol Cell Biochem. 2015 Jul;405(1-2):73-9.
Title:	MiR-492 is functionally involved in Oxaliplatin resistance in colon cancer cells LS174T via its regulating the expression of CD147.
Author:	Peng, Lipan\|Zhu, Huaqiang\|Wang, Jinshen\|Sui, Haina\|Zhang, Honglai\|Jin, Changqing\|Li, Leping\|Xu, Tao\|Miao, Ruizheng
PMID:	25862460

77.
Journal:	Biomaterials. 2015 Sep;62:138-46.
Title:	Bioreactor-engineered cancer tissue-like structures mimic phenotypes, gene expression profiles and drug resistance patterns observed "in vivo".
Author:	Hirt, Christian\|Papadimitropoulos, Adam\|Muraro, Manuele G\|Mele, Valentina\|Panopoulos, Evangelos\|Cremonesi, Eleonora\|Ivanek, Robert\|Schultz-Thater, Elke\|Droeser, Raoul A\|Mengus, Chantal\|Heberer, Michael\|Oertli, Daniel\|Iezzi, Giandomenica\|Zajac, Paul\|Eppenb
PMID:	26051518

78.
Journal:	Int J Oncol. 2015 Dec;47(6):2188-96.
Title:	Goniothalamin enhances TRAIL-induced apoptosis in colorectal cancer cells through DR5 upregulation and cFLIP downregulation.
Author:	Sophonnithiprasert, Thanet\|Nilwarangkoon, Sirinun\|Nakamura, Yukio\|Watanapokasin, Ramida
PMID:	26499766

79.
Journal:	Yao Xue Xue Bao. 2015 Oct;50(10):1252-7.
Title:	[Sensitization of human colon cancer HT-29 cells to TRAIL-induced apoptosis by gambognic acid].
Author:	Ye, Ji-lin\|Yu, You-jiang\|Wu, Ai-lian\|Wang, Dong-yan\|Liu, Yong-chun\|Liu, Yan-qing
PMID:	26837170

80.
Journal:	Oncotarget. 2016 Feb 9;7(6):7161-78.
Title:	The probiotic Propionibacterium freudenreichii as a new adjuvant for TRAIL-based therapy in colorectal cancer.
Author:	Cousin, Fabien J\|Jouan-Lanhouet, Sandrine\|Theret, Nathalie\|Brenner, Catherine\|Jouan, Elodie\|Le Moigne-Muller, Gwenaelle\|Dimanche-Boitrel, Marie-Therese\|Jan, Gwenael
PMID:	26771233

81.
Journal:	Med Phys. 2016 Jul;43(7):4375.
Title:	2D radially compensating excitation pulse in combination with an internal transceiver antenna for 3D MRI of the rectum at 7 T.
Author:	van Kalleveen, I M L\|Kroeze, H\|Sbrizzi, A\|Boer, V O\|Reerink, O\|Philippens, M E P\|van de Berg, C A T\|Luijten, P R\|Klomp, D W J
PMID:	27370152

82.
Journal:	BMC Complement Altern Med. 2016 Oct 1;16(1):384.
Title:	Methylferulate from Tamarix aucheriana inhibits growth and enhances chemosensitivity of human colorectal cancer cells: possible mechanism of action.
Author:	Abaza, Mohamed Salah I\|Afzal, Mohammad\|Al-Attiyah, Raja'a J\|Guleri, Radhika
PMID:	27716288

83.
Journal:	BMC Genomics. 2017 May 30;18(1):421.
Title:	Genome-wide network-based pathway analysis of CSF t-tau/Abeta1-42 ratio in the ADNI cohort.
Author:	Cong, Wang\|Meng, Xianglian\|Li, Jin\|Zhang, Qiushi\|Chen, Feng\|Liu, Wenjie\|Wang, Ying\|Cheng, Sipu\|Yao, Xiaohui\|Yan, Jingwen\|Kim, Sungeun\|Saykin, Andrew J\|Liang, Hong\|Shen, Li
PMID:	28558704

84.
Journal:	Front Immunol. 2017 Oct 25;8:1373.
Title:	TH17 Cell and Epithelial Cell Crosstalk during Inflammatory Bowel Disease and Carcinogenesis.
Author:	Kempski, Jan\|Brockmann, Leonie\|Gagliani, Nicola\|Huber, Samuel
PMID:	29118756

85.
Journal:	Acta Biomater. 2017 Mar 1;50:127-141.
Title:	Endocytosis of cerium oxide nanoparticles and modulation of reactive oxygen species in human ovarian and colon cancer cells.
Author:	Vassie, James A\|Whitelock, John M\|Lord, Megan S
PMID:	27940194

86.
Journal:	J Racial Ethn Health Disparities. 2018 Jun;5(3):530-535.
Title:	Evaluating Two Evidence-Based Intervention Strategies to Promote CRC Screening Among Latino Adults in a Primary Care Setting.
Author:	Castaneda, Sheila F\|Bharti, Balambal\|Espinoza-Giacinto, Rebeca Aurora\|Sanchez, Valerie\|O'Connell, Shawne\|Munoz, Fatima\|Mercado, Sylvia\|Meza, Marie Elena\|Rojas, Wendy\|Talavera, Gregory A\|Gupta, Samir
PMID:	28634873

87.
Journal:	Biol Trace Elem Res. 2018 May;183(1):1-8.
Title:	Trace Element and Heavy Metal Levels in Colorectal Cancer: Comparison Between Cancerous and Non-cancerous Tissues.
Author:	Sohrabi, Masoudreza\|Gholami, Ali\|Azar, MohammadHossein Hosseini\|Yaghoobi, Mohammad\|Shahi, Maryamosadat Mirasgari\|Shirmardi, Solmaz\|Nikkhah, Mehdi\|Kohi, Zahra\|Salehpour, Delaram\|Khoonsari, Mahmood Reza\|Hemmasi, Gholamrez\|Zamani, Farhad\|Sohrabi, Mahmoudreza
PMID:	28795369

88.
Journal:	Mol Pharm. 2018 Mar 5;15(3):994-1004.
Title:	Targeted Delivery and Redox Activity of Folic Acid-Functionalized Nanoceria in Tumor Cells.
Author:	Vassie, James A\|Whitelock, John M\|Lord, Megan S
PMID:	29397735

89.
Journal:	Biochim Biophys Acta Mol Basis Dis. 2018 Aug;1864(8):2600-2609.
Title:	Nogo-B (Reticulon-4B) functions as a negative regulator of the apoptotic pathway through the interaction with c-FLIP in colorectal cancer cells.
Author:	Kawaguchi, Nao\|Tashiro, Keitaro\|Taniguchi, Kohei\|Kawai, Masaru\|Tanaka, Keitaro\|Okuda, Junji\|Hayashi, Michihiro\|Uchiyama, Kazuhisa
PMID:	29684585

90.
Journal:	Eur J Surg Oncol. 2018 Aug;44(8):1241-1246.
Title:	Clinical lymph node staging in colorectal cancer; a flip of the coin?
Author:	Brouwer, Nelleke P M\|Stijns, Rutger C H\|Lemmens, Valery E P P\|Nagtegaal, Iris D\|Beets-Tan, Regina G H\|Futterer, Jurgen J\|Tanis, Pieter J\|Verhoeven, Rob H A\|de Wilt, Johannes H W
PMID:	29739638

91.
Journal:	Oncol Rep. 2018 Aug;40(2):916-922.
Title:	miR218 promotes apoptosis of SW1417 human colon cancer cells by targeting cFLIP.
Author:	Meng, Qingkai\|Chen, Yue\|Lian, Bo\|Shang, Yan\|Yang, Hongmei
PMID:	29845219

92.
Journal:	ACS Appl Mater Interfaces. 2018 Jul 25;10(29):24392-24405.
Title:	Polyamino Acid Layer-by-Layer (LbL) Constructed Silica-Supported Mesoporous Titania Nanocarriers for Stimuli-Responsive Delivery of microRNA 708 and Paclitaxel for Combined Chemotherapy.
Author:	Gupta, Biki\|Ruttala, Hima Bindu\|Poudel, Bijay Kumar\|Pathak, Shiva\|Regmi, Shobha\|Gautam, Milan\|Poudel, Kishwor\|Sung, Min Hyun\|Ou, Wenquan\|Jin, Sung Giu\|Jeong, Jee-Heon\|Ku, Sae Kwang\|Choi, Han-Gon\|Yong, Chul Soon\|Kim, Jong Oh
PMID:	29978708

93.
Journal:	Acad Radiol. 2018 Sep 26. pii: S1076-6332(18)30408-2.
Title:	Correlation Between Intravoxel Incoherent Motion and Dynamic Contrast-Enhanced Magnetic Resonance Imaging Parameters in Rectal Cancer.
Author:	Sun, Hongliang\|Xu, Yanyan\|Xu, Qiaoyu\|Duan, Jianghui\|Zhang, Haibo\|Liu, Tongxi\|Li, Lu\|Chan, Queenie\|Xie, Sheng\|Wang, Wu
PMID:	30268719

94.
Journal:	J Gastroenterol Hepatol. 2018 Oct 30.
Title:	Tauroursodeoxycholic acid attenuates colitis-associated colon cancer by inhibiting nuclear factor kappaB signaling.
Author:	Kim, Young Hoon\|Kim, Jee Hyun\|Kim, Byeong Gwan\|Lee, Kook Lae\|Kim, Ji Won\|Koh, Seong-Joon
PMID:	30378164