Primary Site >> Colorectal Cancer
Gene >> CES2
| 1. | |||||||||||
| Journal: | Clin Cancer Res. 2002 Aug;8(8):2605-11. | ||||||||||
| Title: | Human carboxylesterase 2 is commonly expressed in tumor tissue and is correlated with activation of irinotecan. | ||||||||||
| Author: | Xu, Guang|Zhang, Wanghai|Ma, Margaret K|McLeod, Howard L | ||||||||||
| PMID: | 12171891 | ||||||||||
| 2. | |||||||||||
| Journal: | Br J Cancer. 2002 Sep 9;87(6):659-64. | ||||||||||
| Title: | Secreted and tumour targeted human carboxylesterase for activation of irinotecan. | ||||||||||
| Author: | Oosterhoff, D|Pinedo, H M|van der Meulen, I H|de Graaf, M|Sone, T|Kruyt, F A|van Beusechem, V W|Haisma, H J|Gerritsen, W R | ||||||||||
| PMID: | 12237777 | ||||||||||
| 3. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2002 Apr;49(4):329-35. | ||||||||||
| Title: | Determinants of the cytotoxicity of irinotecan in two human colorectal tumor cell lines. | ||||||||||
| Author: | Pavillard, Valerie|Agostini, Cecile|Richard, Sophie|Charasson, Virginie|Montaudon, Daniele|Robert, Jacques | ||||||||||
| PMID: | 11914913 | ||||||||||
| 4. | |||||||||||
| Journal: | Clin Cancer Res. 2003 Oct 15;9(13):4983-91. | ||||||||||
| Title: | Carboxylesterases expressed in human colon tumor tissue and their role in CPT-11 hydrolysis. | ||||||||||
| Author: | Sanghani, Sonal P|Quinney, Sara K|Fredenburg, Tyler B|Sun, Zejin|Davis, Wilhelmina I|Murry, Daryl J|Cummings, Oscar W|Seitz, David E|Bosron, William F | ||||||||||
| PMID: | 14581373 | ||||||||||
| 5. | |||||||||||
| Journal: | Br J Cancer. 2005 Jan 31;92(2):259-64. | ||||||||||
| Title: | Unfavourable expression of pharmacologic markers in mucinous colorectal cancer. | ||||||||||
| Author: | Glasgow, S C|Yu, J|Carvalho, L P|Shannon, W D|Fleshman, J W|McLeod, H L | ||||||||||
| PMID: | 15655543 | ||||||||||
| 6. | |||||||||||
| Journal: | J Pharmacol Exp Ther. 2005 Jun;313(3):1011-6. | ||||||||||
| Title: | Hydrolysis of capecitabine to 5'-deoxy-5-fluorocytidine by human carboxylesterases and inhibition by loperamide. | ||||||||||
| Author: | Quinney, S K|Sanghani, S P|Davis, W I|Hurley, T D|Sun, Z|Murry, D J|Bosron, W F | ||||||||||
| PMID: | 15687373 | ||||||||||
| 7. | |||||||||||
| Journal: | Clin Cancer Res. 2005 Oct 1;11(19 Pt 1):6901-7. | ||||||||||
| Title: | Carboxylesterase isoform 2 mRNA expression in peripheral blood mononuclear cells is a predictive marker of the irinotecan to SN38 activation step in colorectal cancer patients. | ||||||||||
| Author: | Cecchin, Erika|Corona, Giuseppe|Masier, Sara|Biason, Paola|Cattarossi, Giulio|Frustaci, Sergio|Buonadonna, Angela|Colussi, Annamaria|Toffoli, Giuseppe | ||||||||||
| PMID: | 16203781 | ||||||||||
| 8. | |||||||||||
| Journal: | Cancer Biol Ther. 2006 Nov;5(11):1450-6. Epub 2006 Nov 13. | ||||||||||
| Title: | Transcriptional activation of the carboxylesterase 2 gene by the p53 pathway. | ||||||||||
| Author: | Choi, Woonyoung|Cogdell, David|Feng, Yumei|Hamilton, Stanley R|Zhang, Wei | ||||||||||
| PMID: | 16963839 | ||||||||||
| 9. | |||||||||||
| Journal: | J Pharmacol Exp Ther. 2007 Oct;323(1):94-101. | ||||||||||
| Title: | Expression and characterization of a human carboxylesterase 2 splice variant. | ||||||||||
| Author: | Schiel, Marissa A|Green, Scheri-lyn|Davis, Wilhelmina I|Sanghani, Paresh C|Bosron, William F|Sanghani, Sonal P | ||||||||||
| PMID: | 17636009 | ||||||||||
| 10. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2008 Mar;61(3):481-8. Epub 2007 May 5. | ||||||||||
| Title: | Functional study of the 830C>G polymorphism of the human carboxylesterase 2 gene. | ||||||||||
| Author: | Bellott, Ricardo|Le Morvan, Valerie|Charasson, Virginie|Laurand, Armelle|Colotte, Marthe|Zanger, Ulrich M|Klein, Kathrin|Smith, Denis|Bonnet, Jacques|Robert, Jacques | ||||||||||
| PMID: | 17483951 | ||||||||||
| 11. | |||||||||||
| Journal: | Cancer Invest. 2008 Mar;26(2):178-81. | ||||||||||
| Title: | Carboxylesterase 2 is downregulated in colorectal cancer following progression of the disease. | ||||||||||
| Author: | Tang, Xiaobo|Wu, Hong|Wu, Zhenghua|Wang, Guiyu|Wang, Zhigang|Zhu, Daling | ||||||||||
| PMID: | 18259949 | ||||||||||
| 12. | |||||||||||
| Journal: | Curr Drug Metab. 2008 May;9(4):336-43. | ||||||||||
| Title: | A carboxylesterase 2 gene polymorphism as predictor of capecitabine on response and time to progression. | ||||||||||
| Author: | Ribelles, N|Lopez-Siles, J|Sanchez, A|Gonzalez, E|Sanchez, M J|Carabantes, F|Sanchez-Rovira, P|Marquez, A|Duenas, R|Sevilla, I|Alba, E | ||||||||||
| PMID: | 18473752 | ||||||||||
| 13. | |||||||||||
| Journal: | Br J Cancer. 2008 Oct 21;99(8):1239-45. | ||||||||||
| Title: | Pharmacokinetic and pharmacogenetic determinants of the activity and toxicity of irinotecan in metastatic colorectal cancer patients. | ||||||||||
| Author: | Rouits, E|Charasson, V|Petain, A|Boisdron-Celle, M|Delord, J-P|Fonck, M|Laurand, A|Poirier, A-L|Morel, A|Chatelut, E|Robert, J|Gamelin, E | ||||||||||
| PMID: | 18797458 | ||||||||||
| 14. | |||||||||||
| Journal: | Drug Metab Dispos. 2009 Jul;37(7):1539-47. | ||||||||||
| Title: | Regulation of tissue-specific carboxylesterase expression by pregnane x receptor and constitutive androstane receptor. | ||||||||||
| Author: | Xu, Chenshu|Wang, Xinkun|Staudinger, Jeff L | ||||||||||
| PMID: | 19359405 | ||||||||||
| 15. | |||||||||||
| Journal: | Tumori. 2009 Jul-Aug;95(4):473-8. | ||||||||||
| Title: | Decreased serum levels of carboxylesterase-2 in patients with ovarian cancer. | ||||||||||
| Author: | Cai, Liying|Tang, Xiaobo|Guo, Lei|An, Yuan|Wang, Yuguang|Zheng, Jianhua | ||||||||||
| PMID: | 19856659 | ||||||||||
| 16. | |||||||||||
| Journal: | Int J Cancer. 2010 Sep 1;127(5):1028-37. | ||||||||||
| Title: | Evidence of heterogeneity within colorectal liver metastases for allelic losses, mRNA level expression and in vitro response to chemotherapeutic agents. | ||||||||||
| Author: | Goasguen, Nicolas|de Chaisemartin, Cecile|Brouquet, Antoine|Julie, Catherine|Prevost, Gregoire P|Laurent-Puig, Pierre|Penna, Christophe | ||||||||||
| PMID: | 20017140 | ||||||||||
| 17. | |||||||||||
| Journal: | Clin Cancer Res. 2011 Apr 1;17(7):2006-13. | ||||||||||
| Title: | A polymorphism in the cytidine deaminase promoter predicts severe capecitabine-induced hand-foot syndrome. | ||||||||||
| Author: | Caronia, Daniela|Martin, Miguel|Sastre, Javier|de la Torre, Julio|Garcia-Saenz, Jose Angel|Alonso, Maria R|Moreno, Leticia T|Pita, Guillermo|Diaz-Rubio, Eduardo|Benitez, Javier|Gonzalez-Neira, Anna | ||||||||||
| PMID: | 21325291 | ||||||||||
| 18. | |||||||||||
| Journal: | PLoS Comput Biol. 2011 Sep;7(9):e1002143. | ||||||||||
| Title: | A combined experimental and mathematical approach for molecular-based optimization of irinotecan circadian delivery. | ||||||||||
| Author: | Ballesta, Annabelle|Dulong, Sandrine|Abbara, Chadi|Cohen, Boris|Okyar, Alper|Clairambault, Jean|Levi, Francis | ||||||||||
| PMID: | 21931543 | ||||||||||
| 19. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2012 Jul;70(1):25-32. | ||||||||||
| Title: | Phase II and gene expression analysis trial of neoadjuvant capecitabine plus irinotecan followed by capecitabine-based chemoradiotherapy for locally advanced rectal cancer: Hoosier Oncology Group GI03-53. | ||||||||||
| Author: | Chiorean, E Gabriela|Sanghani, Sonal|Schiel, Marissa A|Yu, Menggang|Burns, Matthew|Tong, Yan|Hinkle, David T|Coleman, Nicki|Robb, Bruce|LeBlanc, Julia|Clark, Romnee|Bufill, Jose|Curie, Colleen|Loehrer, Patrick J|Cardenes, Higinia | ||||||||||
| PMID: | 22610353 | ||||||||||
| 20. | |||||||||||
| Journal: | Br J Pharmacol. 2013 Apr;168(8):1989-99. | ||||||||||
| Title: | Regulation of carboxylesterase-2 expression by p53 family proteins and enhanced anti-cancer activities among 5-fluorouracil, irinotecan and doxazolidine prodrug. | ||||||||||
| Author: | Xiao, Da|Yang, Dongfang|Guo, Liangran|Lu, Wei|Charpentier, Margaret|Yan, Bingfang | ||||||||||
| PMID: | 23373735 | ||||||||||
| 21. | |||||||||||
| Journal: | Neoplasma. 2014;61(1):99-109. | ||||||||||
| Title: | Relationship between the expression of CES2, UGT1A1, and GUSB in colorectal cancer tissues and aberrant methylation. | ||||||||||
| Author: | Xie, F W|Peng, Y|Chen, Xiong|Chen, Xi|Li, J|Wang, W|Yu, Z|Ouyang, X | ||||||||||
| PMID: | 24195516 | ||||||||||
| 22. | |||||||||||
| Journal: | Biomed Pharmacother. 2014 Feb;68(1):31-7. | ||||||||||
| Title: | Regulation and expression of aberrant methylation on irinotecan metabolic genes CES2, UGT1A1 and GUSB in the in-vitro cultured colorectal cancer cells. | ||||||||||
| Author: | Xie, Fang-Wei|Peng, Yong-Hai|Chen, Xi|Chen, Xiong|Li, Jie|Yu, Zong-Yang|Wang, Wen-Wu|Ouyang, Xue-Nong | ||||||||||
| PMID: | 24439671 | ||||||||||
| 23. | |||||||||||
| Journal: | J Pharmacol Exp Ther. 2014 Oct;351(1):61-6. | ||||||||||
| Title: | Pegylation improves the pharmacokinetics and bioavailability of small-molecule drugs hydrolyzable by esterases: a study of phospho-Ibuprofen. | ||||||||||
| Author: | Mattheolabakis, George|Wong, Chi C|Sun, Yu|Amella, Carol A|Richards, Robert|Constantinides, Panayiotis P|Rigas, Basil | ||||||||||
| PMID: | 25047517 | ||||||||||
| 24. | |||||||||||
| Journal: | Int J Mol Sci. 2014 Sep 5;15(9):15767-77. | ||||||||||
| Title: | CES2, ABCG2, TS and Topo-I primary and synchronous metastasis expression and clinical outcome in metastatic colorectal cancer patients treated with first-line FOLFIRI regimen. | ||||||||||
| Author: | Silvestris, Nicola|Simone, Giovanni|Partipilo, Giulia|Scarpi, Emanuela|Lorusso, Vito|Brunetti, Anna Elisabetta|Maiello, Evaristo|Paradiso, Angelo|Mangia, Anita | ||||||||||
| PMID: | 25198900 | ||||||||||
| 25. | |||||||||||
| Journal: | Biomed Pharmacother. 2014 Sep;68(7):825-31. | ||||||||||
| Title: | Influence of UGT1A1 gene methylation level in colorectal cancer cells on the sensitivity of the chemotherapy drug CPT-11. | ||||||||||
| Author: | Xie, Fang-Wei|Peng, Yong-Hai|Wang, Wen-Wu|Chen, Xi|Chen, Xiong|Li, Jie|Yu, Zong-Yang|Ouyang, Xue-Nong | ||||||||||
| PMID: | 25260839 | ||||||||||
| 26. | |||||||||||
| Journal: | Cancer Lett. 2016 Aug 1;378(1):51-8. | ||||||||||
| Title: | Tissue-infiltrating plasma cells are an important source of carboxylesterase 2 contributing to the therapeutic efficacy of prodrugs. | ||||||||||
| Author: | Kuhl, Anja A|Erben, Ulrike|Cieluch, Constanze|Spieckermann, Simone|Grone, Jorn|Lohneis, Philipp|Pape, Ulrich Frank|Arsenic, Ruza|Utku, Nalan | ||||||||||
| PMID: | 27149931 | ||||||||||
| 27. | |||||||||||
| Journal: | Oncotarget. 2016 Nov 15;7(46):75279-75292. | ||||||||||
| Title: | High-throughput proteomics integrated with gene microarray for discovery of colorectal cancer potential biomarkers. | ||||||||||
| Author: | Yu, Jiekai|Li, Xiaofen|Zhong, Chenhan|Li, Dan|Zhai, Xiaohui|Hu, Wangxiong|Guo, Cheng|Yuan, Ying|Zheng, Shu | ||||||||||
| PMID: | 27661117 | ||||||||||
| 28. | |||||||||||
| Journal: | Chembiochem. 2017 Jul 4;18(13):1204-1215. | ||||||||||
| Title: | Glycoengineering of Esterase Activity through Metabolic Flux-Based Modulation of Sialic Acid. | ||||||||||
| Author: | Mathew, Mohit P|Tan, Elaine|Labonte, Jason W|Shah, Shivam|Saeui, Christopher T|Liu, Lingshu|Bhattacharya, Rahul|Bovonratwet, Patawut|Gray, Jeffrey J|Yarema, Kevin J | ||||||||||
| PMID: | 28218815 | ||||||||||
| 29. | |||||||||||
| Journal: | Dis Markers. 2018 Jan 31;2018:5280736. | ||||||||||
| Title: | The Relationship between TP53 Gene Status and Carboxylesterase 2 Expression in Human Colorectal Cancer. | ||||||||||
| Author: | Ishimine, Momoko|Lee, Hyeon-Cheol|Nakaoka, Hirofumi|Orita, Hajime|Kobayashi, Toshiyuki|Mizuguchi, Konomi|Endo, Mikumi|Inoue, Ituro|Sato, Koichi|Yokomizo, Takehiko | ||||||||||
| PMID: | 29651325 | ||||||||||
| 30. | |||||||||||
| Journal: | Biol Pharm Bull. 2018;41(5):697-706. | ||||||||||
| Title: | Development of a Caco-2 Cell Line Carrying the Human Intestine-Type CES Expression Profile as a Promising Tool for Ester-Containing Drug Permeability Studies. | ||||||||||
| Author: | Ishizaki, Yuma|Furihata, Tomomi|Oyama, Yusuke|Ohura, Kayoko|Imai, Teruko|Hosokawa, Masakiyo|Akita, Hidetaka|Chiba, Kan | ||||||||||
| PMID: | 29709907 | ||||||||||