Primary Site >> Colorectal Cancer

Gene >> CES1

Journal: Digestion. 1992;51(1):10-7.
Title: Regulation of cholesterol metabolism and low-density lipoprotein binding in human intestinal Caco-2 cells.
Author: Reimann, F M|Herold, G|Grosshans, I|Rogler, G|Fellermann, K|Stange, E F
PMID: 1639221
Journal: Cancer Chemother Pharmacol. 2002 Apr;49(4):329-35.
Title: Determinants of the cytotoxicity of irinotecan in two human colorectal tumor cell lines.
Author: Pavillard, Valerie|Agostini, Cecile|Richard, Sophie|Charasson, Virginie|Montaudon, Daniele|Robert, Jacques
PMID: 11914913
Journal: Clin Cancer Res. 2002 Aug;8(8):2605-11.
Title: Human carboxylesterase 2 is commonly expressed in tumor tissue and is correlated with activation of irinotecan.
Author: Xu, Guang|Zhang, Wanghai|Ma, Margaret K|McLeod, Howard L
PMID: 12171891
Journal: Clin Cancer Res. 2003 Oct 15;9(13):4983-91.
Title: Carboxylesterases expressed in human colon tumor tissue and their role in CPT-11 hydrolysis.
Author: Sanghani, Sonal P|Quinney, Sara K|Fredenburg, Tyler B|Sun, Zejin|Davis, Wilhelmina I|Murry, Daryl J|Cummings, Oscar W|Seitz, David E|Bosron, William F
PMID: 14581373
Journal: J Pharmacol Exp Ther. 2005 Jun;313(3):1011-6.
Title: Hydrolysis of capecitabine to 5'-deoxy-5-fluorocytidine by human carboxylesterases and inhibition by loperamide.
Author: Quinney, S K|Sanghani, S P|Davis, W I|Hurley, T D|Sun, Z|Murry, D J|Bosron, W F
PMID: 15687373
Journal: Eur J Cancer. 2008 Jan;44(2):310-7.
Title: Gene expression predicts differential capecitabine metabolism, impacting on both pharmacokinetics and antitumour activity.
Author: Guichard, Sylvie M|Macpherson, Janet S|Mayer, Iain|Reid, Eilidh|Muir, Morwenna|Dodds, Michael|Alexander, Susan|Jodrell, Duncan I
PMID: 18077151
Journal: Cancer Chemother Pharmacol. 2012 Jul;70(1):25-32.
Title: Phase II and gene expression analysis trial of neoadjuvant capecitabine plus irinotecan followed by capecitabine-based chemoradiotherapy for locally advanced rectal cancer: Hoosier Oncology Group GI03-53.
Author: Chiorean, E Gabriela|Sanghani, Sonal|Schiel, Marissa A|Yu, Menggang|Burns, Matthew|Tong, Yan|Hinkle, David T|Coleman, Nicki|Robb, Bruce|LeBlanc, Julia|Clark, Romnee|Bufill, Jose|Curie, Colleen|Loehrer, Patrick J|Cardenes, Higinia
PMID: 22610353
Journal: J Pharmacol Exp Ther. 2014 Oct;351(1):61-6.
Title: Pegylation improves the pharmacokinetics and bioavailability of small-molecule drugs hydrolyzable by esterases: a study of phospho-Ibuprofen.
Author: Mattheolabakis, George|Wong, Chi C|Sun, Yu|Amella, Carol A|Richards, Robert|Constantinides, Panayiotis P|Rigas, Basil
PMID: 25047517
Journal: Biochem Biophys Res Commun. 2015 Feb 13;457(3):363-9.
Title: 3D-fibroblast tissues constructed by a cell-coat technology enhance tight-junction formation of human colon epithelial cells.
Author: Matsusaki, Michiya|Hikimoto, Daichi|Nishiguchi, Akihiro|Kadowaki, Koji|Ohura, Kayoko|Imai, Teruko|Akashi, Mitsuru
PMID: 25576862
Journal: ANZ J Surg. 2017 Oct;87(10):E112-E115.
Title: Colorectal multidisciplinary meetings: how do they affect the timeliness of treatment?
Author: Nikolovski, Zoran|Watters, David A K|Stupart, Douglas|Guest, Glenn D
PMID: 25913227
Journal: Chembiochem. 2017 Jul 4;18(13):1204-1215.
Title: Glycoengineering of Esterase Activity through Metabolic Flux-Based Modulation of Sialic Acid.
Author: Mathew, Mohit P|Tan, Elaine|Labonte, Jason W|Shah, Shivam|Saeui, Christopher T|Liu, Lingshu|Bhattacharya, Rahul|Bovonratwet, Patawut|Gray, Jeffrey J|Yarema, Kevin J
PMID: 28218815
Journal: Pharmacol Res. 2017 Jun;120:133-137.
Title: Identification of new SNPs associated with severe toxicity to capecitabine.
Author: Pellicer, Marta|Garcia-Gonzalez, Xandra|Garcia, Maria I|Robles, Luis|Gravalos, Cristina|Garcia-Alfonso, Pilar|Pachon, Vanessa|Longo, Federico|Martinez, Virginia|Blanco, Carolina|Iglesias, Irene|Sanjurjo, Maria|Lopez-Fernandez, Luis A
PMID: 28347776
Journal: Biol Pharm Bull. 2018;41(5):697-706.
Title: Development of a Caco-2 Cell Line Carrying the Human Intestine-Type CES Expression Profile as a Promising Tool for Ester-Containing Drug Permeability Studies.
Author: Ishizaki, Yuma|Furihata, Tomomi|Oyama, Yusuke|Ohura, Kayoko|Imai, Teruko|Hosokawa, Masakiyo|Akita, Hidetaka|Chiba, Kan
PMID: 29709907