Primary Site >> Colorectal Cancer

Gene >> CDX2

Journal: Int J Cancer. 1997 Feb 20;74(1):35-44.
Title: Molecular cloning, sequencing and expression of the mRNA encoding human Cdx1 and Cdx2 homeobox. Down-regulation of Cdx1 and Cdx2 mRNA expression during colorectal carcinogenesis.
Author: Mallo, G V|Rechreche, H|Frigerio, J M|Rocha, D|Zweibaum, A|Lacasa, M|Jordan, B R|Dusetti, N J|Dagorn, J C|Iovanna, J L
PMID: 9036867
Journal: Ann Hum Genet. 1997 Sep;61(Pt 5):393-400.
Title: Cloning and chromosome assignment of the human CDX2 gene.
Author: Drummond, F|Putt, W|Fox, M|Edwards, Y H
PMID: 9459001
Journal: J Biol Chem. 1998 May 29;273(22):14030-6.
Title: Expression of the Cdx1 and Cdx2 homeotic genes leads to reduced malignancy in colon cancer-derived cells.
Author: Mallo, G V|Soubeyran, P|Lissitzky, J C|Andre, F|Farnarier, C|Marvaldi, J|Dagorn, J C|Iovanna, J L
PMID: 9593754
Journal: Oncogene. 1998 Aug 6;17(5):657-9.
Title: CDX2, a human homologue of Drosophila caudal, is mutated in both alleles in a replication error positive colorectal cancer.
Author: Wicking, C|Simms, L A|Evans, T|Walsh, M|Chawengsaksophak, K|Beck, F|Chenevix-Trench, G|Young, J|Jass, J|Leggett, B|Wainwright, B
PMID: 9704932
Journal: Oncogene. 1999 Sep 2;18(35):5010-4.
Title: CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling.
Author: da Costa, L T|He, T C|Yu, J|Sparks, A B|Morin, P J|Polyak, K|Laken, S|Vogelstein, B|Kinzler, K W
PMID: 10490837
Journal: Mol Cell Biol Res Commun. 2000 May;3(5):271-6.
Title: Overexpression of Cdx1 and Cdx2 homeogenes enhances expression of the HLA-I in HT-29 cells.
Author: Soubeyran, P|Mallo, G V|Moucadel, V|Dagorn, J C|Iovanna, J L
PMID: 10964750
Journal: Br J Cancer. 2001 Jan;84(2):218-25.
Title: The homeobox gene CDX2 in colorectal carcinoma: a genetic analysis.
Author: Sivagnanasundaram, S|Islam, I|Talbot, I|Drummond, F|Walters, J R|Edwards, Y H
PMID: 11161380
Journal: Br J Cancer. 2001 May 18;84(10):1314-6.
Title: CDX2 mutations do not account for juvenile polyposis or Peutz-Jeghers syndrome and occur infrequently in sporadic colorectal cancers.
Author: Woodford-Richens, K L|Halford, S|Rowan, A|Bevan, S|Aaltonen, L A|Wasan, H|Bicknell, D|Bodmer, W F|Houlston, R S|Tomlinson, I P
PMID: 11355940
Journal: Oncogene. 2001 Aug 9;20(35):4884-90.
Title: Expression of the gut-enriched Kruppel-like factor (Kruppel-like factor 4) gene in the human colon cancer cell line RKO is dependent on CDX2.
Author: Dang, D T|Mahatan, C S|Dang, L H|Agboola, I A|Yang, V W
PMID: 11521200
Journal: Int J Oncol. 2002 Jan;20(1):23-9.
Title: The caudal-related homeodomain protein CDX1 activates proliferating cell nuclear antigen expression in hepatocellular and colorectal carcinoma cells.
Author: Oh, Eun-Jin|Park, Jae-Hong|Cho, Mong|Lee, Won-Jae|Choi, Yung Hyun|Yoo, Mi-Ae
PMID: 11743638
Journal: Gut. 2002 Apr;50(4):525-9.
Title: Stimulation of the intestinal Cdx2 homeobox gene by butyrate in colon cancer cells.
Author: Domon-Dell, C|Wang, Q|Kim, S|Kedinger, M|Evers, B M|Freund, J-N
PMID: 11889074
Journal: FEBS Lett. 2002 May 8;518(1-3):83-7.
Title: Stimulation of Cdx1 by oncogenic beta-catenin/Tcf4 in colon cancer cells; opposite effect of the CDX2 homeoprotein.
Author: Domon-Dell, Claire|Freund, Jean-Noel
PMID: 11997022
Journal: Gut. 2002 Aug;51(2):184-90.
Title: Expression of CDX2 in normal and neoplastic human colon tissue and during differentiation of an in vitro model system.
Author: Qualtrough, D|Hinoi, T|Fearon, E|Paraskeva, C
PMID: 12117877
Journal: Gastroenterology. 2002 Nov;123(5):1565-77.
Title: CDX2 regulates liver intestine-cadherin expression in normal and malignant colon epithelium and intestinal metaplasia.
Author: Hinoi, Takao|Lucas, Peter C|Kuick, Rork|Hanash, Samir|Cho, Kathleen R|Fearon, Eric R
PMID: 12404231
Journal: Am J Surg Pathol. 2003 Mar;27(3):303-10.
Title: CDX2, a highly sensitive and specific marker of adenocarcinomas of intestinal origin: an immunohistochemical survey of 476 primary and metastatic carcinomas.
Author: Werling, Robert W|Yaziji, Hadi|Bacchi, Carlos E|Gown, Allen M
PMID: 12604886
Journal: J Biol Chem. 2003 Sep 19;278(38):36611-20. Epub 2003 Jul 10.
Title: Lewis type 1 antigen synthase (beta3Gal-T5) is transcriptionally regulated by homeoproteins.
Author: Isshiki, Soichiro|Kudo, Takashi|Nishihara, Shoko|Ikehara, Yuzuru|Togayachi, Akira|Furuya, Akiko|Shitara, Kenya|Kubota, Tetsuro|Watanabe, Masahiko|Kitajima, Masaki|Narimatsu, Hisashi
PMID: 12855703
Journal: J Biol Chem. 2003 Nov 7;278(45):44608-16. Epub 2003 Aug 28.
Title: Silencing of CDX2 expression in colon cancer via a dominant repression pathway.
Author: Hinoi, Takao|Loda, Massimo|Fearon, Eric R
PMID: 12947088
Journal: Virchows Arch. 2003 Oct;443(4):579-82.
Title: Oncocytic adenocarcinoma of the rectum with diffuse intra-luminal microcalcifications: the first reported case.
Author: Piscitelli, Domenico|Ingravallo, Giuseppe|Resta, Leonardo|Fiore, Maria G|Maiorano, Eugenio
PMID: 12955503
Journal: Gut. 2003 Oct;52(10):1465-71.
Title: The Cdx2 homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut development.
Author: Bonhomme, C|Duluc, I|Martin, E|Chawengsaksophak, K|Chenard, M-P|Kedinger, M|Beck, F|Freund, J-N|Domon-Dell, C
PMID: 12970140
Journal: Oncogene. 2003 Sep 11;22(39):7942-9.
Title: CDX2, a homeobox transcription factor, upregulates transcription of the p21/WAF1/CIP1 gene.
Author: Bai, Yun-Qing|Miyake, Satoshi|Iwai, Takehisa|Yuasa, Yasuhito
PMID: 12970742
Journal: Mod Pathol. 2003 Sep;16(9):913-9.
Title: Cdx2 protein expression in normal and malignant human tissues: an immunohistochemical survey using tissue microarrays.
Author: Moskaluk, Christopher A|Zhang, Hong|Powell, Steven M|Cerilli, Lisa A|Hampton, Garret M|Frierson, Henry F Jr
PMID: 13679455
Journal: Cancer Res. 2003 Sep 1;63(17):5564-72.
Title: Tumor-specific immunological recognition of frameshift-mutated peptides in colon cancer with microsatellite instability.
Author: Ishikawa, Toshiaki|Fujita, Tomonobu|Suzuki, Yuriko|Okabe, Satoshi|Yuasa, Yasuhito|Iwai, Takehisa|Kawakami, Yutaka
PMID: 14500396
Journal: Nat Genet. 2003 Dec;35(4):323-30. Epub 2003 Nov 16.
Title: Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2+/- compound mutant mice.
Author: Aoki, Koji|Tamai, Yoshitaka|Horiike, Shigeo|Oshima, Masanobu|Taketo, Makoto M
PMID: 14625550
Journal: Biochem Biophys Res Commun. 2004 Feb 27;315(1):93-9.
Title: Homeodomain protein CDX2 regulates COX-2 expression in colorectal cancer.
Author: Kim, Sang-Pyo|Park, Jong-Wook|Lee, Sung-Hee|Lim, Jun Hee|Jang, Byeong-Churl|Lee, Sang-Han|Jang, In-Hwan|Freund, Jean-Noel|Suh, Seong-Il|Mun, Kyo Cheol|Song, Dae-Kyu|Ha, Eun-Mi|Lee, Won-Jae|Kwon, Taeg Kyu
PMID: 15013430
Journal: Am J Surg Pathol. 2004 Apr;28(4):442-52.
Title: Primary mucinous (so-called colloid) carcinomas of the lung: a clinicopathologic and immunohistochemical study with special reference to CDX-2 homeobox gene and MUC2 expression.
Author: Rossi, Giulio|Murer, Bruno|Cavazza, Alberto|Losi, Lorena|Natali, Pamela|Marchioni, Alessandro|Migaldi, Mario|Capitanio, Giovanni|Brambilla, Elisabeth
PMID: 15087663
Journal: J Biol Chem. 2004 Aug 13;279(33):34397-405. Epub 2004 Jun 9.
Title: The tumor suppressor adenomatous polyposis coli and caudal related homeodomain protein regulate expression of retinol dehydrogenase L.
Author: Jette, Cicely|Peterson, Peter W|Sandoval, Imelda T|Manos, Elizabeth J|Hadley, Eryn|Ireland, Chris M|Jones, David A
PMID: 15190067
Journal: J Biol Chem. 2004 Aug 27;279(35):36865-75. Epub 2004 Jun 23.
Title: Cdx1 inhibits human colon cancer cell proliferation by reducing beta-catenin/T-cell factor transcriptional activity.
Author: Guo, Rong-Jun|Huang, Edward|Ezaki, Toshihiko|Patel, Neesha|Sinclair, Kristen|Wu, Jinling|Klein, Peter|Suh, Eun-Ran|Lynch, John P
PMID: 15215241
Journal: Am J Surg Pathol. 2004 Aug;28(8):1026-32.
Title: Immunophenotypic differences between intestinal-type and low-grade papillary sinonasal adenocarcinomas: an immunohistochemical study of 22 cases utilizing CDX2 and MUC2.
Author: Cathro, Helen P|Mills, Stacey E
PMID: 15252308
Journal: FEBS Lett. 2004 Aug 27;573(1-3):147-54.
Title: Cdx2 homeodomain protein regulates the expression of MOK, a member of the mitogen-activated protein kinase superfamily, in the intestinal epithelial cells.
Author: Uesaka, Toshihiro|Kageyama, Noriko
PMID: 15327990
Journal: Am J Clin Pathol. 2004 Sep;122(3):421-7.
Title: Usefulness of Cdx2 in separating mucinous bronchioloalveolar adenocarcinoma of the lung from metastatic mucinous colorectal adenocarcinoma.
Author: Saad, Reda S|Cho, Patrick|Silverman, Jan F|Liu, Yulin
PMID: 15362373
Journal: Cancer Res. 2004 Oct 1;64(19):6973-7.
Title: Down-regulation of the homeodomain factor Cdx2 in colorectal cancer by collagen type I: an active role for the tumor environment in malignant tumor progression.
Author: Brabletz, Thomas|Spaderna, Simone|Kolb, Jochen|Hlubek, Falk|Faller, Gerhard|Bruns, Christiane J|Jung, Andreas|Nentwich, Jens|Duluc, Isabelle|Domon-Dell, Claire|Kirchner, Thomas|Freund, Jean-Noel
PMID: 15466189
Journal: Pol J Pathol. 2004;55(3):9-14.
Title: CDX-2 expression is reduced in colorectal carcinomas with solid growth pattern and proximal location, but is largely independent of MSI status.
Author: Okon, Krzysztof|Zazula, Monika|Rudzki, Zbigniew|Papla, Boleslaw|Osuch, Czeslaw|Stachura, Jerzy
PMID: 15619975
Journal: Mod Pathol. 2005 Jan;18(1):19-25.
Title: Use of novel immunohistochemical markers expressed in colonic adenocarcinoma to distinguish primary ovarian tumors from metastatic colorectal carcinoma.
Author: Logani, Sanjay|Oliva, Esther|Arnell, Paula M|Amin, Mahul B|Young, Robert H
PMID: 15389251
Journal: Oncol Rep. 2005 Mar;13(3):547-51.
Title: Promoter methylation downregulates CDX2 expression in colorectal carcinomas.
Author: Kawai, Hiroshi|Tomii, Kunitoshi|Toyooka, Shinichi|Yano, Masaaki|Murakami, Masakazu|Tsukuda, Kazunori|Shimizu, Nobuyoshi
PMID: 15706431
Journal: J Pathol. 2005 Apr;205(5):615-22.
Title: CDX2 co-localizes with liver-intestine cadherin in intestinal metaplasia and adenocarcinoma of the stomach.
Author: Ko, Samuel|Chu, Kent-Man|Luk, John Moon-Ching|Wong, Bonnie Wing-Yan|Yuen, Siu-Tsan|Leung, Suet-Yi|Wong, John
PMID: 15732140
Journal: Am J Physiol Gastrointest Liver Physiol. 2005 Aug;289(2):G285-90. Epub 2005 Mar
Title: Differential regulation of intestinal alkaline phosphatase gene expression by Cdx1 and Cdx2.
Author: Alkhoury, Fuad|Malo, Madhu S|Mozumder, Moushumi|Mostafa, Golam|Hodin, Richard A
PMID: 15774940
Journal: Mod Pathol. 2005 Sep;18(9):1217-22.
Title: Value of CDX2, villin, and alpha-methylacyl coenzyme A racemase immunostains in the distinction between primary adenocarcinoma of the bladder and secondary colorectal adenocarcinoma.
Author: Suh, Namsoo|Yang, Ximing J|Tretiakova, Maria S|Humphrey, Peter A|Wang, Hanlin L
PMID: 15803184
Journal: Gastroenterology. 2005 Apr;128(4):946-61.
Title: CDX2-regulated expression of iron transport protein hephaestin in intestinal and colonic epithelium.
Author: Hinoi, Takao|Gesina, Galina|Akyol, Aytekin|Kuick, Rork|Hanash, Samir|Giordano, Thomas J|Gruber, Stephen B|Fearon, Eric R
PMID: 15825077
Journal: Appl Immunohistochem Mol Morphol. 2005 Jun;13(2):142-6.
Title: Expression of CDX2, cytokeratins 7 and 20 in sinonasal intestinal-type adenocarcinoma.
Author: Ortiz-Rey, Jose A|Alvarez, Carlos|San Miguel, Pilar|Iglesias, Begona|Anton, Iosu
PMID: 15894926
Journal: Cancer Res. 2005 Jul 1;65(13):5488-92.
Title: CDX2 polymorphisms, RNA expression, and risk of colorectal cancer.
Author: Rozek, Laura S|Lipkin, Steven M|Fearon, Eric R|Hanash, Samir|Giordano, Thomas J|Greenson, Joel K|Kuick, Rork|Misek, David E|Taylor, Jeremy M G|Douglas, Julie A|Rennert, Gad|Gruber, Stephen B
PMID: 15994917
Journal: Oncogene. 2005 Dec 1;24(54):7955-63.
Title: Phosphorylation of the homeotic tumor suppressor Cdx2 mediates its ubiquitin-dependent proteasome degradation.
Author: Gross, Isabelle|Lhermitte, Benoit|Domon-Dell, Claire|Duluc, Isabelle|Martin, Elisabeth|Gaiddon, Christian|Kedinger, Michele|Freund, Jean-Noel
PMID: 16027724
Journal: Pathol Int. 2005 Sep;55(9):550-7.
Title: Establishment and characterization of a human colonic mucinous carcinoma cell line with predominant goblet-cell differentiation from liver metastasis.
Author: Yamachika, Takasuke|Nakanishi, Hayao|Yasui, Kenzo|Ikehara, Yuzuru|Niwa, Toru|Wanibuchi, Hideki|Tatematsu, Masae|Fukushima, Shoji
PMID: 16143030
Journal: Korean J Gastroenterol. 2005 Sep;46(3):204-10.
Title: [Expression of Cdx2 protein in colorectal cancer].
Author: Pack, Jong Hae|Kim, Tae Dong|Oh, Heun Ah|Lee, Eun Joo|Kim, Jun Whan|Jang, Byung Ik|Kim, Tae Nyeun|Jung, Moon Kwan|Bae, Young Kyung
PMID: 16179840
Journal: Oncol Rep. 2005 Dec;14(6):1559-64.
Title: Decrease in size of azoxymethane induced colon carcinoma in F344 rats by 180-day fermented miso.
Author: Ohuchi, Yoshie|Myojin, Yuki|Shimamoto, Fumio|Kashimoto, Naoki|Kamiya, Kenji|Watanabe, Hiromitsu
PMID: 16273256
Journal: Appl Immunohistochem Mol Morphol. 2005 Dec;13(4):342-6.
Title: Potential diagnostic utility of CDX-2 immunophenotyping in extramammary Paget's disease.
Author: Zeng, Hao Audrey|Cartun, Richard|Ricci, Andrew Jr
PMID: 16280663
Journal: Clin Cancer Res. 2005 Dec 15;11(24 Pt 1):8549-56.
Title: The putative tumor suppressor Cdx2 is overexpressed by human colorectal adenocarcinomas.
Author: Witek, Matthew E|Nielsen, Karl|Walters, Rhonda|Hyslop, Terry|Palazzo, Juan|Schulz, Stephanie|Waldman, Scott A
PMID: 16361536
Journal: Korean J Intern Med. 2005 Dec;20(4):317-24.
Title: Relationships between the expressions of CDX1 and CDX2 mRNA and clinicopathologic features in colorectal cancers.
Author: Kim, Gwang Ha|Lee, Dong Hyun|Kim, Hyung Wook|Cheong, Jong Yun|Seo, Soo Boon|Heo, Jeong|Kang, Dae Hwan|Song, Geun Am|Cho, Mong|Yang, Ung Suk|Park, Do Youn|Yoo, Mi Ae
PMID: 16491830
Journal: Oncogene. 2006 Apr 6;25(15):2264-72.
Title: CDX2 has tumorigenic potential in the human colon cancer cell lines LOVO and SW48.
Author: Dang, L H|Chen, F|Ying, C|Chun, S Y|Knock, S A|Appelman, H D|Dang, D T
PMID: 16314840
Journal: APMIS. 2006 Jan;114(1):50-4.
Title: Altered expression of CDX2 in colorectal cancers.
Author: Choi, Byung Jun|Kim, Chang Jae|Cho, Yong Gu|Song, Jae Hwi|Kim, Su Young|Nam, Suk Woo|Lee, Sug Hyung|Yoo, Nam Jin|Lee, Jung Young|Park, Won Sang
PMID: 16499661
Journal: Hum Pathol. 2006 Jul;37(7):809-15.
Title: Invasive colorectal micropapillary carcinoma: an aggressive variant of adenocarcinoma.
Author: Kim, Mi-Jung|Hong, Seung-Mo|Jang, Se J|Yu, Eunsil|Kim, Jung-Sun|Kim, Kyu-Rae|Gong, Gyungyub|Ro, Jae Y
PMID: 16784979
Journal: Hum Pathol. 2007 Jan;38(1):72-8.
Title: Expression of CDX2 in benign tissue and adenocarcinoma of the prostate.
Author: Herawi, Mehsati|De Marzo, Angelo M|Kristiansen, Glen|Epstein, Jonathan I
PMID: 16949907
Journal: Histol Histopathol. 2007 Mar;22(3):251-60.
Title: Loss of MUC2 expression correlates with progression along the adenoma-carcinoma sequence pathway as well as de novo carcinogenesis in the colon.
Author: Mizoshita, T|Tsukamoto, T|Inada, K I|Hirano, N|Tajika, M|Nakamura, T|Ban, H|Tatematsu, M
PMID: 17163399
Journal: Am J Pathol. 2007 Feb;170(2):733-44.
Title: The microenvironment controls CDX2 homeobox gene expression in colorectal cancer cells.
Author: Benahmed, Fairouz|Gross, Isabelle|Guenot, Dominique|Jehan, Frederic|Martin, Elisabeth|Domon-Dell, Claire|Brabletz, Thomas|Kedinger, Michele|Freund, Jean-Noel|Duluc, Isabelle
PMID: 17255339
Journal: J Gastroenterol Hepatol. 2007 Mar;22(3):389-94.
Title: Expression of the caudal-type homeodomain transcription factor CDX2 is related to clinical outcome in biliary tract carcinoma.
Author: Chang, Yu-Ting|Hsu, Chiun|Jeng, Yung-Ming|Chang, Ming-Chu|Wei, Shu-Chen|Wong, Jau-Min
PMID: 17295772
Journal: Oncogene. 2007 Jul 12;26(32):4725-9. Epub 2007 Feb 5.
Title: CDX2 promotes anchorage-independent growth by transcriptional repression of IGFBP-3.
Author: Chun, S Y|Chen, F|Washburn, J G|MacDonald, J W|Innes, K L|Zhao, R|Cruz-Correa, M R|Dang, L H|Dang, D T
PMID: 17297462
Journal: Arch Pathol Lab Med. 2007 Apr;131(4):599-603.
Title: Distinguishing prostatic from colorectal adenocarcinoma on biopsy samples: the role of morphology and immunohistochemistry.
Author: Owens, Christopher L|Epstein, Jonathan I|Netto, George J
PMID: 17425391
Journal: Int J Cancer. 2007 Sep 15;121(6):1219-26.
Title: Epigenetic silencing of CDX2 is a feature of squamous esophageal cancer.
Author: Guo, MingZhou|House, Michael G|Suzuki, Hiromu|Ye, Ying|Brock, Malcolm V|Lu, Fengmin|Liu, Zhihua|Rustgi, Anil K|Herman, James G
PMID: 17534889
Journal: Oncol Rep. 2007 Jul;18(1):87-92.
Title: CDX2 as a useful marker of colorectal adenocarcinoma metastases to lung in pre-operative biopsy specimens.
Author: Tanaka, Shigebumi|Saito, Kana|Ito, Tomokazu|Tajima, Kohei|Mogi, Akira|Shitara, Yoshinori|Sano, Takaaki|Kuwano, Hiroyuki
PMID: 17549351
Journal: Mod Pathol. 2007 Dec;20(12):1286-97. Epub 2007 Sep 28.
Title: CDX2 expression is progressively decreased in human gastric intestinal metaplasia, dysplasia and cancer.
Author: Liu, Qiang|Teh, Ming|Ito, Kosei|Shah, Nilesh|Ito, Yoshiaki|Yeoh, Khay Guan
PMID: 17906616
Journal: C R Biol. 2007 Nov;330(11):821-7. Epub 2007 Sep 7.
Title: Multiple-contrast X-ray micro-CT visualization of colon malformations and tumours in situ in living mice.
Author: Choquet, Philippe|Calon, Alexandre|Breton, Elodie|Beck, Felix|Domon-Dell, Claire|Freund, Jean-Noel|Constantinesco, Andre
PMID: 17923376
Journal: Cancer Res. 2007 Oct 15;67(20):9721-30.
Title: Mouse model of colonic adenoma-carcinoma progression based on somatic Apc inactivation.
Author: Hinoi, Takao|Akyol, Aytekin|Theisen, Brian K|Ferguson, David O|Greenson, Joel K|Williams, Bart O|Cho, Kathleen R|Fearon, Eric R
PMID: 17942902
Journal: Cancer Epidemiol Biomarkers Prev. 2007 Dec;16(12):2752-5.
Title: CDX2 VDR polymorphism and colorectal cancer.
Author: Slattery, Martha L|Herrick, Jennifer|Wolff, Roger K|Caan, Bette J|Potter, John D|Sweeney, Carol
PMID: 18086783
Journal: Oncogene. 2008 Jan 3;27(1):107-15. Epub 2007 Jun 25.
Title: The intestine-specific homeobox gene Cdx2 decreases mobility and antagonizes dissemination of colon cancer cells.
Author: Gross, I|Duluc, I|Benameur, T|Calon, A|Martin, E|Brabletz, T|Kedinger, M|Domon-Dell, C|Freund, J-N
PMID: 17599044
Journal: Biochimie. 2008 May;90(5):697-704.
Title: Differential regulation of CDX1 and CDX2 gene expression by deficiency in methyl group donors.
Author: Lu, Xiaohong|Freund, Jean-Noel|Muller, Marc|Ravey, Juliette|Nicolas, Jean-Pierre|Gueant, Jean-Louis|Namour, Fares
PMID: 18187048
Journal: Hum Pathol. 2008 Apr;39(4):543-9.
Title: Prostatic adenocarcinoma in colorectal biopsy: clinical and pathologic features.
Author: Lane, Zhaoli|Epstein, Jonathan I|Ayub, Salman|Netto, George J
PMID: 18234278
Journal: Dig Liver Dis. 2008 Sep;40(9):749-54.
Title: Clinicopathological analysis of colorectal cancer liver metastasis and intrahepatic cholangiocarcinoma: are they just apples and oranges?
Author: Chiu, C-T|Chiang, J-M|Yeh, T-S|Tseng, J-H|Chen, T-C|Jan, Y-Y|Chen, M-F
PMID: 18329969
Journal: Oncogene. 2008 Jul 24;27(32):4497-502.
Title: Cdx1, a dispensable homeobox gene for gut development with limited effect in intestinal cancer.
Author: Bonhomme, C|Calon, A|Martin, E|Robine, S|Neuville, A|Kedinger, M|Domon-Dell, C|Duluc, I|Freund, J-N
PMID: 18372917
Journal: Lancet Oncol. 2008 Jun;9(6):596-9.
Title: Carcinoma of unknown primary with a colon-cancer profile-changing paradigm and emerging definitions.
Author: Varadhachary, Gauri R|Raber, Martin N|Matamoros, Aurelio|Abbruzzese, James L
PMID: 18510991
Journal: Histol Histopathol. 2008 Sep;23(9):1043-7.
Title: Expression of homeodomain protein CDX2 in colorectal adenoma and adenocarcinoma.
Author: Bakaris, Sevgi|Cetinkaya, Ali|Ezberci, Fikret|Ekerbicer, Hasan
PMID: 18581275
Journal: Mod Pathol. 2008 Nov;21(11):1403-12.
Title: Differential diagnostic and functional role of the multi-marker phenotype CDX2/CK20/CK7 in colorectal cancer stratified by mismatch repair status.
Author: Lugli, Alessandro|Tzankov, Alexandar|Zlobec, Inti|Terracciano, Luigi Maria
PMID: 18587323
Journal: Int J Clin Exp Pathol. 2008 Jan 1;1(5):457-60.
Title: Invasive micropapillary carcinoma of the sigmoid colon: distinct morphology and aggressive behavior.
Author: Wen, Ping|Xu, Yiqing|Frankel, Wendy L|Shen, Rulong
PMID: 18787620
Journal: Mol Cancer Res. 2008 Sep;6(9):1478-90.
Title: Repression of the desmocollin 2 gene expression in human colon cancer cells is relieved by the homeodomain transcription factors Cdx1 and Cdx2.
Author: Funakoshi, Shinsuke|Ezaki, Toshihiko|Kong, Jianping|Guo, Rong Jun|Lynch, John P
PMID: 18819935
Journal: Exp Cell Res. 2008 Dec 10;314(20):3712-23.
Title: KLF4 regulation in intestinal epithelial cell maturation.
Author: Flandez, M|Guilmeau, S|Blache, P|Augenlicht, L H
PMID: 18977346
Journal: Mutat Res. 2009 Jan 15;660(1-2):12-21.
Title: Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways.
Author: Slattery, Martha L|Wolff, Roger K|Curtin, Karen|Fitzpatrick, Frank|Herrick, Jennifer|Potter, John D|Caan, Bette J|Samowitz, Wade S
PMID: 18992263
Journal: Hum Pathol. 2009 Mar;40(3):398-404.
Title: Differentiating the undifferentiated: immunohistochemical profile of medullary carcinoma of the colon with an emphasis on intestinal differentiation.
Author: Winn, Brody|Tavares, Rosemarie|Fanion, Jacqueline|Noble, Lelia|Gao, John|Sabo, Edmond|Resnick, Murray B
PMID: 18992917
Journal: Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1936-41.
Title: Gastrointestinal differentiation marker Cytokeratin 20 is regulated by homeobox gene CDX1.
Author: Chan, Carol W M|Wong, Newton A|Liu, Ying|Bicknell, David|Turley, Helen|Hollins, Laura|Miller, Crispin J|Wilding, Jennifer L|Bodmer, Walter F
PMID: 19188603
Journal: Mol Cell Biochem. 2009 Nov;331(1-2):27-30.
Title: No association between the polymorphisms in CDX2 coding regions and colorectal cancer in Chinese.
Author: Xia, Xiaoping|Xu, Enping|Quan, Sheng|Huang, Qiong|Lai, Maode
PMID: 19421714
Journal: Int J Cancer. 2009 Dec 15;125(12):2802-9.
Title: KLF4-dependent, PPARgamma-induced expression of GPA33 in colon cancer cell lines.
Author: Rageul, Julie|Mottier, Stephanie|Jarry, Anne|Shah, Yatrik|Theoleyre, Sandrine|Masson, Damien|Gonzalez, Frank J|Laboisse, Christian L|Denis, Marc G
PMID: 19551868
Journal: Clin Cancer Res. 2009 Jul 15;15(14):4665-73.
Title: Relationship of CDX2 loss with molecular features and prognosis in colorectal cancer.
Author: Baba, Yoshifumi|Nosho, Katsuhiko|Shima, Kaori|Freed, Ellen|Irahara, Natsumi|Philips, Juliet|Meyerhardt, Jeffrey A|Hornick, Jason L|Shivdasani, Ramesh A|Fuchs, Charles S|Ogino, Shuji
PMID: 19584150
Journal: Anticancer Res. 2009 Sep;29(9):3511-36.
Title: The relevance of vitamin D receptor (VDR) gene polymorphisms for cancer: a review of the literature.
Author: Kostner, Kim|Denzer, Nicole|Muller, Cornelia S L|Klein, Rolf|Tilgen, Wolfgang|Reichrath, Jorg
PMID: 19667145
Journal: Cell Signal. 2009 Dec;21(12):1846-56.
Title: Down-regulation of Cdx2 in colorectal carcinoma cells by the Raf-MEK-ERK 1/2 pathway.
Author: Krueger, Felix|Madeja, Zofia|Hemberger, Myriam|McMahon, Martin|Cook, Simon J|Gaunt, Stephen J
PMID: 19686845
Journal: Mol Cancer. 2009 Sep 25;8:77.
Title: Selective activation of tumor growth-promoting Ca2+ channel MS4A12 in colon cancer by caudal type homeobox transcription factor CDX2.
Author: Koslowski, Michael|Tureci, Ozlem|Huber, Christoph|Sahin, Ugur
PMID: 19781065
Journal: Virchows Arch. 2009 Dec;455(6):527-31.
Title: Colonic carcinoma with a pancreatic acinar cell differentiation. A case report.
Author: Chiaravalli, Anna Maria|Finzi, Giovanna|Bertolini, Valentina|La Rosa, Stefano|Capella, Carlo
PMID: 19908063
Journal: Anticancer Res. 2009 Dec;29(12):5033-7.
Title: CDX2 expression in cutaneous metastatic carcinomas and extramammary Paget's Disease.
Author: Lora, Viviana|Kanitakis, Jean
PMID: 20044613
Journal: J Microbiol Biotechnol. 2009 Dec;19(12):1557-64.
Title: Purification of caudal-related homeodomain transcription factor and its binding characterization.
Author: Jeong, Mi Suk|Hwang, Eun Young|Kim, Hyun Tae|Yoo, Mi-Ae|Jang, Se Bok
PMID: 20075618
Journal: Zhonghua Wai Ke Za Zhi. 2009 Nov 15;47(22):1689-92.
Title: [Pathologic study of circumferential margin involvement in middle and lower rectal cancer].
Author: Yu, Bin|Yu, Yue-ming|Chen, Yan-ning|Li, Yong-tao
PMID: 20137717
Journal: Akush Ginekol (Sofiia). 2009;48(5):20-2.
Title: [Differential diagnostic importance of immunochistochemistry applied at metastases of adenocarcinomas of the peritoneum].
Author: Porjazova, E|Zaprjanov, Z|Batashki, I|Milchev, N|Markova, D
PMID: 20198793
Journal: Carcinogenesis. 2010 Feb;31(2):159-66.
Title: The intestine-specific transcription factor Cdx2 inhibits beta-catenin/TCF transcriptional activity by disrupting the beta-catenin-TCF protein complex.
Author: Guo, Rong-Jun|Funakoshi, Shinsuke|Lee, Hannah H|Kong, Jianping|Lynch, John P
PMID: 19734199
Journal: Hum Pathol. 2010 Jan;41(1):123-8.
Title: Expression of the intestinal biomarkers Guanylyl cyclase C and CDX2 in poorly differentiated colorectal carcinomas.
Author: Winn, Brody|Tavares, Rosemarie|Matoso, Andres|Noble, Lelia|Fanion, Jacqueline|Waldman, Scott A|Resnick, Murray B
PMID: 19800103
Journal: Gastroenterology. 2010 Feb;138(2):627-35.
Title: CDX transcription factors positively regulate expression of solute carrier family 5, member 8 in the colonic epithelium.
Author: Kakizaki, Fumihiko|Aoki, Koji|Miyoshi, Hiroyuki|Carrasco, Nancy|Aoki, Masahiro|Taketo, Makoto M
PMID: 19900445
Journal: Int J Cancer. 2010 Jul 15;127(2):367-80.
Title: Clinicopathological and protein characterization of BRAF- and K-RAS-mutated colorectal cancer and implications for prognosis.
Author: Zlobec, Inti|Bihl, Michel P|Schwarb, Heike|Terracciano, Luigi|Lugli, Alessandro
PMID: 19908233
Journal: Jpn J Clin Oncol. 2010 Mar;40(3):208-13.
Title: CK7, CK20, CDX2 and MUC2 Immunohistochemical staining used to distinguish metastatic colorectal carcinoma involving ovary from primary ovarian mucinous adenocarcinoma.
Author: Shin, Jung Ha|Bae, Jeong Hoon|Lee, Ahwon|Jung, Chan-Kwon|Yim, Hyeon Woo|Park, Jong-Sup|Lee, Kyo-Young
PMID: 19926591
Journal: Curr Opin Gastroenterol. 2010 May;26(3):280-5.
Title: Ampullary cancer.
Author: Heinrich, Stefan|Clavien, Pierre-Alain
PMID: 20168227
Journal: Nutr Cancer. 2010;62(4):436-42.
Title: Calcium, vitamin D, VDR genotypes, and epigenetic and genetic changes in rectal tumors.
Author: Slattery, Martha L|Wolff, Roger K|Herrick, Jennifer S|Caan, Bette J|Samowitz, Wade
PMID: 20432164
Journal: Oncol Rep. 2010 Jul;24(1):97-104.
Title: Hypoxia-inducible factor-1alpha modulates the down-regulation of the homeodomain protein CDX2 in colorectal cancer.
Author: Zheng, Jianbao|Sun, Xuejun|Wang, Wei|Lu, Shaoying
PMID: 20514449
Journal: Int J Colorectal Dis. 2010 Oct;25(10):1231-42.
Title: New insights into the development and differentiation of the human anorectal epithelia. Are there clinical consequences?
Author: Fritsch, Helga|Zehm, Sarah|Illig, Romana|Moser, Patrizia|Aigner, Felix
PMID: 20563874
Journal: Cancer Biol Ther. 2010 Aug 1;10(3):211-8. Epub 2010 Aug 11.
Title: Corruption of homeostatic mechanisms in the guanylyl cyclase C signaling pathway underlying colorectal tumorigenesis.
Author: Li, Peng|Waldman, Scott A
PMID: 20592492
Journal: Int J Oncol. 2010 Sep;37(3):707-18.
Title: Characterization of rectal, proximal and distal colon cancers based on clinicopathological, molecular and protein profiles.
Author: Minoo, P|Zlobec, I|Peterson, M|Terracciano, L|Lugli, A
PMID: 20664940
Journal: Am J Physiol Gastrointest Liver Physiol. 2010 Nov;299(5):G1054-67.
Title: Intestine-specific transcription factor Cdx2 induces E-cadherin function by enhancing the trafficking of E-cadherin to the cell membrane.
Author: Funakoshi, Shinsuke|Kong, Jianping|Crissey, Mary Ann|Dang, Long|Dang, Duyen|Lynch, John P
PMID: 20671195
Journal: Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15157-62.
Title: TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions.
Author: Verzi, Michael P|Hatzis, Pantelis|Sulahian, Rita|Philips, Juliet|Schuijers, Jurian|Shin, Hyunjin|Freed, Ellen|Lynch, John P|Dang, Duyen T|Brown, Myles|Clevers, Hans|Liu, X Shirley|Shivdasani, Ramesh A
PMID: 20696899
Journal: Cancer Res. 2010 Sep 1;70(17):6767-78.
Title: CDX2 regulates multidrug resistance 1 gene expression in malignant intestinal epithelium.
Author: Takakura, Yuji|Hinoi, Takao|Oue, Naohide|Sasada, Tatsunari|Kawaguchi, Yasuo|Okajima, Masazumi|Akyol, Aytekin|Fearon, Eric R|Yasui, Wataru|Ohdan, Hideki
PMID: 20699370
Journal: Histopathology. 2010 Aug;57(2):233-43.
Title: Systematic assessment of protein phenotypes characterizing high-grade tumour budding in mismatch repair-proficient colorectal cancer.
Author: Karamitopoulou, Eva|Lugli, Alessandro|Panayiotides, Ioannis|Karakitsos, Petros|Peros, George|Rallis, George|Patsouris, Efstratios S|Terracciano, Luigi|Zlobec, Inti
PMID: 20716165
Journal: Pathol Int. 2010 Oct;60(10):673-80.
Title: Immunohistochemical analysis of colorectal cancer with gastric phenotype: claudin-18 is associated with poor prognosis.
Author: Matsuda, Miho|Sentani, Kazuhiro|Noguchi, Tsuyoshi|Hinoi, Takao|Okajima, Masazumi|Matsusaki, Keisuke|Sakamoto, Naoya|Anami, Katsuhiro|Naito, Yutaka|Oue, Naohide|Yasui, Wataru
PMID: 20846265
Journal: Int J Surg Pathol. 2011 Dec;19(6):787-90.
Title: Colonic carcinoma metastatic to the endometrium: the importance of clinical history in averting misdiagnosis as a primary endometrial carcinoma.
Author: Zannoni, Gian Franco|Vellone, Valerio Gaetano|Fadda, Guido|Petrillo, Marco|Scambia, Giovanni
PMID: 19443868
Journal: Inflamm Bowel Dis. 2011 Jan;17(1):232-40.
Title: Immunohistochemical expression of CDX2, beta-catenin, and TP53 in inflammatory bowel disease-associated colorectal cancer.
Author: Laurent, Camille|Svrcek, Magali|Flejou, Jean-Francois|Chenard, Marie-Pierre|Duclos, Bernard|Freund, Jean-Noel|Reimund, Jean-Marie
PMID: 20815042
Journal: J Biol Chem. 2011 Jan 7;286(1):450-9.
Title: Oct1 is a switchable, bipotential stabilizer of repressed and inducible transcriptional states.
Author: Shakya, Arvind|Kang, Jinsuk|Chumley, Jeffrey|Williams, Matthew A|Tantin, Dean
PMID: 21051540
Journal: Cancer Res. 2011 Jan 15;71(2):593-602.
Title: Suppression of colonic polyposis by homeoprotein CDX2 through its nontranscriptional function that stabilizes p27Kip1.
Author: Aoki, Koji|Kakizaki, Fumihiko|Sakashita, Hiromi|Manabe, Toshiaki|Aoki, Masahiro|Taketo, Makoto M
PMID: 21224344
Journal: Pathology. 2011 Feb;43(2):133-7.
Title: Loss of E-cadherin independently predicts the lymph node status in colorectal cancer.
Author: Karamitopoulou, E|Zlobec, I|Patsouris, Es|Peros, G|Lugli, A
PMID: 21233674
Journal: BMC Cancer. 2011 Feb 1;11:51.
Title: Mechanisms of confluence-dependent expression of CD26 in colon cancer cell lines.
Author: Abe, Masako|Havre, Pamela A|Urasaki, Yasuyo|Ohnuma, Kei|Morimoto, Chikao|Dang, Long H|Dang, Nam H
PMID: 21284881
Journal: Hum Pathol. 2011 Jul;42(7):1047-52.
Title: A novel case of rhabdoid colon carcinoma associated with a positive CpG island methylator phenotype and BRAF mutation.
Author: Pancione, Massimo|Di Blasi, Arturo|Sabatino, Lina|Fucci, Alessandra|Dalena, Anna Maria|Palombi, Natalia|Carotenuto, Pietro|Aquino, Gabriella|Daniele, Bruno|Normanno, Nicola|Colantuoni, Vittorio
PMID: 21315413
Journal: Br J Cancer. 2011 Mar 15;104(6):1000-6.
Title: Clinical significance of CDX2-positive circulating tumour cells in colorectal cancer patients.
Author: Wong, S C C|Ng, S S M|Cheung, M T|Luk, L Y|Chan, C M L|Cheung, A H K|Lee, V H M|Lai, P B S|Ma, B B Y|Hui, E P|Lam, M Y Y|Au, T C C|Chan, A T C
PMID: 21364588
Journal: Cancer Epidemiol Biomarkers Prev. 2011 May;20(5):1003-16.
Title: Meta-analyses of vitamin D intake, 25-hydroxyvitamin D status, vitamin D receptor polymorphisms, and colorectal cancer risk.
Author: Touvier, Mathilde|Chan, Doris S M|Lau, Rosa|Aune, Dagfinn|Vieira, Rui|Greenwood, Darren C|Kampman, Ellen|Riboli, Elio|Hercberg, Serge|Norat, Teresa
PMID: 21378269
Journal: APMIS. 2011 Jun;119(6):393-8.
Title: Filiform serrated adenomatous polyposis arising in a diverted rectum of an inflammatory bowel disease patient.
Author: Klarskov, Louise|Mogensen, Anne Mellon|Jespersen, Niels|Ingeholm, Peter|Holck, Susanne
PMID: 21569098
Journal: BMC Gastroenterol. 2011 May 20;11:59.
Title: Small invasive colon cancer with systemic metastasis: a case report.
Author: Matsumoto, Minori|Nakajima, Takeshi|Kato, Ken|Kouno, Tsutomu|Sakamoto, Taku|Matsuda, Takahisa|Kushima, Ryoji|Saito, Yutaka
PMID: 21595976
Journal: Pathol Oncol Res. 2011 Sep;17(3):743-51.
Title: Effects of homeodomain protein CDX2 expression on the proliferation and migration of lovo colon cancer cells.
Author: Zheng, Jian-bao|Sun, Xue-jun|Qi, Jie|Li, Shou-shuai|Wang, Wei|Ren, Hai-liang|Tian, Yong|Lu, Shao-ying|Du, Jun-kai
PMID: 21626348
Journal: J Pathol. 2011 Nov;225(3):336-43.
Title: Comprehensive analysis of CpG island methylator phenotype (CIMP)-high, -low, and -negative colorectal cancers based on protein marker expression and molecular features.
Author: Zlobec, Inti|Bihl, Michel|Foerster, Anja|Rufle, Alex|Lugli, Alessandro
PMID: 21660972
Journal: Hum Pathol. 2011 Dec;42(12):1888-96.
Title: Systematic analysis of proteins from different signaling pathways in the tumor center and the invasive front of colorectal cancer.
Author: Karamitopoulou, Eva|Zlobec, Inti|Panayiotides, Ioannis|Patsouris, Efstratios S|Peros, George|Rallis, George|Lapas, Christos|Karakitsos, Petros|Terracciano, Luigi M|Lugli, Alessandro
PMID: 21664646
Journal: Gac Med Mex. 2011 Sep-Oct;147(5):432-6.
Title: [A rare case of colorectal micropapillary carcinoma].
Author: Lino-Silva, Leonardo Saul|Salcedo-Hernandez, Rosa Angelica
PMID: 22089678
Journal: Nihon Shokakibyo Gakkai Zasshi. 2011 Dec;108(12):2016-22.
Title: [Advanced poorly differentiated adenocarcinoma of the colon with micropapillary carcinoma components except specific cytokeratin expressions, report of a case].
Author: Takahashi, Sho|Kuroiwa, Ganji|Hirayama, Michiaki|Tobioka, Hirotoshi
PMID: 22139489
Journal: World J Gastroenterol. 2011 Nov 14;17(42):4729-33.
Title: Neuroendocrine and squamous colonic composite carcinoma: case report with molecular analysis.
Author: Wentz, Sabrina C|Vnencak-Jones, Cindy|Chopp, William V
PMID: 22180717
Journal: J Korean Surg Soc. 2011 Dec;81 Suppl 1:S43-6.
Title: Metastasis to the breast from colonic adenocarcinoma.
Author: Noh, Kyoung Tae|Oh, Boyoung|Sung, Sun Hee|Lee, Ryung-Ah|Chung, Soon Sup|Moon, Byung In|Kim, Kwang Ho
PMID: 22319737
Journal: Tsitologiia. 2011;53(12):930-8.
Title: [The interaction between CDX2 transcription factor and DDX5 RNA helicase].
Author: Liskovykh, M A|Davydov-Sinitsin, A P|Marilovtseva, E V|Tomilin, A N|Tolkunova, E N
PMID: 22359951
Journal: Mol Carcinog. 2012 May;51(5):411-21.
Title: Right-side and left-side colon cancer follow different pathways to relapse.
Author: Bauer, Kerry M|Hummon, Amanda B|Buechler, Steven
PMID: 21656576
Journal: Nucleic Acids Res. 2012 Apr;40(8):3456-69.
Title: Cdx2 homeoprotein inhibits non-homologous end joining in colon cancer but not in leukemia cells.
Author: Renouf, Benjamin|Soret, Christine|Saandi, Thoueiba|Delalande, Francois|Martin, Elisabeth|Vanier, Marie|Duluc, Isabelle|Gross, Isabelle|Freund, Jean-Noel|Domon-Dell, Claire
PMID: 22189105
Journal: Gastroenterology. 2012 Apr;142(4):875-885.e3.
Title: Cdx2 controls expression of the protocadherin Mucdhl, an inhibitor of growth and beta-catenin activity in colon cancer cells.
Author: Hinkel, Isabelle|Duluc, Isabelle|Martin, Elisabeth|Guenot, Dominique|Freund, Jean-Noel|Gross, Isabelle
PMID: 22202456
Journal: Diagn Pathol. 2012 Jan 23;7:9.
Title: The value of CDX2 and cytokeratins 7 and 20 expression in differentiating colorectal adenocarcinomas from extraintestinal gastrointestinal adenocarcinomas: cytokeratin 7-/20+ phenotype is more specific than CDX2 antibody.
Author: Bayrak, Reyhan|Haltas, Hacer|Yenidunya, Sibel
PMID: 22268990
Journal: J Med Case Rep. 2012 Feb 13;6:58.
Title: Atypical presentation of colon adenocarcinoma: a case report.
Author: Tumwine, Lynnette K|Kagimu, Magid|Ocama, Ponsiano|Segamwenge, Innocent|Masiira-Mukasa, Noah|Wamala, Dan|Dworak, Otto|Opio, Christopher K
PMID: 22330123
Journal: Int J Colorectal Dis. 2012 Nov;27(11):1391-9.
Title: Loss of desmocollin 1-3 and homeobox genes PITX1 and CDX2 are associated with tumor progression and survival in colorectal carcinoma.
Author: Knosel, Thomas|Chen, Yuan|Hotovy, Stefanie|Settmacher, Utz|Altendorf-Hofmann, Annelore|Petersen, Iver
PMID: 22438068
Journal: Am J Surg Pathol. 2012 Jul;36(7):1087-92.
Title: Detection of human papillomavirus in small cell carcinomas of the anus and rectum.
Author: Cimino-Mathews, Ashley|Sharma, Rajni|Illei, Peter B
PMID: 22531171
Journal: Proc Natl Acad Sci U S A. 2012 May 15;109(20):7776-81.
Title: Transcription factors c-Myc and CDX2 mediate E-selectin ligand expression in colon cancer cells undergoing EGF/bFGF-induced epithelial-mesenchymal transition.
Author: Sakuma, Keiichiro|Aoki, Masahiro|Kannagi, Reiji
PMID: 22547830
Journal: Am J Physiol Gastrointest Liver Physiol. 2012 Jul 15;303(2):G209-19.
Title: Type 2 cGMP-dependent protein kinase regulates proliferation and differentiation in the colonic mucosa.
Author: Wang, Rui|Kwon, In-Kiu|Thangaraju, Muthusamy|Singh, Nagendra|Liu, Kebin|Jay, Philippe|Hofmann, Franz|Ganapathy, Vadivel|Browning, Darren D
PMID: 22556146
Journal: PLoS One. 2012;7(6):e37174.
Title: Caudal homeobox protein Cdx-2 cooperates with Wnt pathway to regulate claudin-1 expression in colon cancer cells.
Author: Bhat, Ajaz A|Sharma, Ashok|Pope, Jillian|Krishnan, Moorthy|Washington, Mary K|Singh, Amar B|Dhawan, Punita
PMID: 22719836
Journal: N Z Med J. 2012 Jun 8;125(1356):47-51.
Title: Vitamin D receptor polymorphisms in colorectal cancer in New Zealand: an association study.
Author: Bentley, Robert W|Keown, Dayle A|Gearry, Richard B|Cameron, Vicky A|Keenan, Jacqui|Roberts, Rebecca L|Day, Andrew S
PMID: 22729058
Journal: PLoS One. 2012;7(7):e36075.
Title: Alleviation of gut inflammation by Cdx2/Pxr pathway in a mouse model of chemical colitis.
Author: Dou, Wei|Mukherjee, Subhajit|Li, Hao|Venkatesh, Madhukumar|Wang, Hongwei|Kortagere, Sandhya|Peleg, Ariel|Chilimuri, Sridhar S|Wang, Zheng-Tao|Feng, Ying|Fearon, Eric R|Mani, Sridhar
PMID: 22815676
Journal: Am J Surg Pathol. 2012 Sep;36(9):1385-94.
Title: Histomorphologic and molecular features of pouch and peripouch adenocarcinoma: a comparison with ulcerative colitis-associated adenocarcinoma.
Author: Jiang, Wei|Shadrach, Bonnie|Carver, Paula|Goldblum, John R|Shen, Bo|Liu, Xiuli
PMID: 22895272
Journal: Curr Biol. 2012 Sep 25;22(18):1705-10.
Title: Sox2 acts through Sox21 to regulate transcription in pluripotent and differentiated cells.
Author: Kuzmichev, Andrey N|Kim, Suel-Kee|D'Alessio, Ana C|Chenoweth, Josh G|Wittko, Ina M|Campanati, Loraine|McKay, Ronald D
PMID: 22902753
Journal: Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):E3196-205.
Title: CDX2 is an amplified lineage-survival oncogene in colorectal cancer.
Author: Salari, Keyan|Spulak, Mary E|Cuff, Justin|Forster, Andrew D|Giacomini, Craig P|Huang, Stephanie|Ko, Melissa E|Lin, Albert Y|van de Rijn, Matt|Pollack, Jonathan R
PMID: 23112155
Journal: PLoS One. 2012;7(11):e47545.
Title: Reg IV is a direct target of intestinal transcriptional factor CDX2 in gastric cancer.
Author: Naito, Yutaka|Oue, Naohide|Hinoi, Takao|Sakamoto, Naoya|Sentani, Kazuhiro|Ohdan, Hideki|Yanagihara, Kazuyoshi|Sasaki, Hiroki|Yasui, Wataru
PMID: 23133598
Journal: Clin Cancer Res. 2012 Nov 15;18(22):6136-46.
Title: Expression profiling of archival tumors for long-term health studies.
Author: Waldron, Levi|Ogino, Shuji|Hoshida, Yujin|Shima, Kaori|McCart Reed, Amy E|Simpson, Peter T|Baba, Yoshifumi|Nosho, Katsuhiko|Segata, Nicola|Vargas, Ana Cristina|Cummings, Margaret C|Lakhani, Sunil R|Kirkner, Gregory J|Giovannucci, Edward|Quackenbush, John|
PMID: 23136189
Journal: Oncogene. 2013 Aug 8;32(32):3782-8.
Title: Regulation of the tumor suppressor homeogene Cdx2 by HNF4alpha in intestinal cancer.
Author: Saandi, T|Baraille, F|Derbal-Wolfrom, L|Cattin, A-L|Benahmed, F|Martin, E|Cardot, P|Duclos, B|Ribeiro, A|Freund, J-N|Duluc, I
PMID: 22986531
Journal: Oncogene. 2013 Sep 5;32(36):4313-8.
Title: Increasing the oxygen load by treatment with myo-inositol trispyrophosphate reduces growth of colon cancer and modulates the intestine homeobox gene Cdx2.
Author: Derbal-Wolfrom, L|Pencreach, E|Saandi, T|Aprahamian, M|Martin, E|Greferath, R|Tufa, E|Choquet, P|Lehn, J-M|Nicolau, C|Duluc, I|Freund, J-N
PMID: 23045284
Journal: J Clin Invest. 2013 Jan;123(1):299-314.
Title: CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARgamma signaling.
Author: Faber, Katrin|Bullinger, Lars|Ragu, Christine|Garding, Angela|Mertens, Daniel|Miller, Christina|Martin, Daniela|Walcher, Daniel|Dohner, Konstanze|Dohner, Hartmut|Claus, Rainer|Plass, Christoph|Sykes, Stephen M|Lane, Steven W|Scholl, Claudia|Frohling, Stef
PMID: 23202735
Journal: BMJ Case Rep. 2013 Jan 25;2013. pii: bcr-2012-007667.
Title: Enteric adenocarcinoma lung: a rare presentation in an Omani woman.
Author: Qureshi, Asim|Furrukh, Muhammad
PMID: 23355573
Journal: Mod Pathol. 2013 Jul;26(7):944-54.
Title: Lynch syndrome-associated breast cancers do not overexpress chromosome 11-encoded mucins.
Author: Walsh, Michael D|Cummings, Margaret C|Pearson, Sally-Ann|Clendenning, Mark|Walters, Rhiannon J|Nagler, Belinda|Hopper, John L|Jenkins, Mark A|Suthers, Graeme K|Goldblatt, Jack|Tucker, Kathy|Gattas, Michael R|Arnold, Julie L|Parry, Susan|Macrae, Finlay A|M
PMID: 23370770
Journal: Carcinogenesis. 2013 Jun;34(6):1361-9.
Title: Regulation of APC and AXIN2 expression by intestinal tumor suppressor CDX2 in colon cancer cells.
Author: Olsen, Anders Kruger|Coskun, Mehmet|Bzorek, Michael|Kristensen, Michael Holmsgaard|Danielsen, Erik Thomas|Jorgensen, Steffen|Olsen, Jorgen|Engel, Ulla|Holck, Susanne|Troelsen, Jesper Thorvald
PMID: 23393221
Journal: Diagn Pathol. 2013 Feb 20;8:31.
Title: Right-sided rhabdoid colorectal tumors might be related to the serrated pathway.
Author: Pancione, Massimo|Remo, Andrea|Sabatino, Lina|Zanella, Caterina|Votino, Carolina|Fucci, Alessandra|Di Blasi, Arturo|Lepore, Giovanni|Daniele, Bruno|Fenizia, Francesca|Molinari, Enrico|Normanno, Nicola|Manfrin, Erminia|Vendraminelli, Roberto|Colantuoni, Vi
PMID: 23425390
Journal: BMJ Case Rep. 2013 Feb 25;2013. pii: bcr-2012-007849.
Title: Testicular metastasis of colorectal carcinoma: an unusual presentation.
Author: Verma, Nidhi|Babu, Suresh|Kushwaha, Jitendra Kumar|Singhai, Atin
PMID: 23440985
Journal: BMC Cancer. 2013 Mar 22;13:142.
Title: Alcohol dehydrogenase, iron containing, 1 promoter hypermethylation associated with colorectal cancer differentiation.
Author: Tae, Chung Hyun|Ryu, Kyung Ju|Kim, Seok-Hyung|Kim, Hee Cheol|Chun, Ho-Kyung|Min, Byung-Hoon|Chang, Dong Kyung|Rhee, Poong-Lyul|Kim, Jae J|Rhee, Jong Chul|Kim, Young-Ho
PMID: 23517143
Journal: Oncotarget. 2013 Feb;4(2):174-5.
Title: Deregulation of the CDX2-KLF4 axis in acute myeloid leukemia and colon cancer.
Author: Rouhi, Arefeh|Frohling, Stefan
PMID: 23563447
Journal: Am Surg. 2013 Apr;79(4):353-60.
Title: Reduced CDX2 expression predicts poor overall survival in patients with colorectal cancer.
Author: Hong, Kwang Dae|Lee, Dooseok|Lee, Youngseok|Lee, Sun Il|Moon, Hong Young
PMID: 23574843
Journal: Mod Pathol. 2013 Sep;26(9):1270-8.
Title: Endometriosis involving the mucosa of the intestinal tract: a clinicopathologic study of 15 cases.
Author: Jiang, Wei|Roma, Andres A|Lai, Keith|Carver, Paula|Xiao, Shu-Yuan|Liu, Xiuli
PMID: 23579618
Journal: Mod Pathol. 2013 Dec;26(12):1642-56.
Title: Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.
Author: Walsh, Michael D|Clendenning, Mark|Williamson, Elizabeth|Pearson, Sally-Ann|Walters, Rhiannon J|Nagler, Belinda|Packenas, David|Win, Aung K|Hopper, John L|Jenkins, Mark A|Haydon, Andrew M|Rosty, Christophe|English, Dallas R|Giles, Graham G|McGuckin, Micha
PMID: 23807779
Journal: Eur J Pharm Biopharm. 2013 Sep;85(1):20-5.
Title: The role of CDX2 in Caco-2 cell differentiation.
Author: Natoli, Manuela|Christensen, Jon|El-Gebali, Sara|Felsani, Armando|Anderle, Pascale
PMID: 23958315
Journal: Am J Surg Pathol. 2013 Oct;37(10):1532-41.
Title: Loss of CDX2/CK20 expression is associated with poorly differentiated carcinoma, the CpG island methylator phenotype, and adverse prognosis in microsatellite-unstable colorectal cancer.
Author: Kim, Jung Ho|Rhee, Ye-Young|Bae, Jeong Mo|Cho, Nam-Yun|Kang, Gyeong Hoon
PMID: 24025523
Journal: Cancer Epidemiol. 2013 Dec;37(6):905-7.
Title: Vitamin D receptor polymorphism and colorectal cancer-specific and all-cause mortality.
Author: Perna, Laura|Hoffmeister, Michael|Schottker, Ben|Arndt, Volker|Haug, Ulrike|Holleczek, Bernd|Burwinkel, Barbara|Ordonez-Mena, Jose M|Brenner, Hermann
PMID: 24075799
Journal: Front Oncol. 2013 Oct 11;3:265.
Title: Loss of Cdx2 Expression in Primary Tumors and Lymph Node Metastases is Specific for Mismatch Repair-Deficiency in Colorectal Cancer.
Author: Dawson, Heather|Koelzer, Viktor H|Lukesch, Anne C|Mallaev, Makhmudbek|Inderbitzin, Daniel|Lugli, Alessandro|Zlobec, Inti
PMID: 24130965
Journal: J Transl Med. 2013 Nov 28;11:297.
Title: The chromatin remodelling component SMARCB1/INI1 influences the metastatic behavior of colorectal cancer through a gene signature mapping to chromosome 22.
Author: Pancione, Massimo|Remo, Andrea|Zanella, Caterina|Sabatino, Lina|Di Blasi, Arturo|Laudanna, Carmelo|Astati, Laura|Rocco, Michele|Bifano, Delfina|Piacentini, Paolo|Pavan, Laura|Purgato, Alberto|Greco, Filippo|Talamini, Alberto|Bonetti, Andrea|Ceccarelli, Mi
PMID: 24286138
Journal: Int J Clin Oncol. 2014;19(3):479-84.
Title: Carcinoma of unknown primary with gastrointestinal profile: immunohistochemistry and survival data for this favorable subset.
Author: Varadhachary, G R|Karanth, S|Qiao, W|Carlson, H R|Raber, M N|Hainsworth, J D|Greco, F A
PMID: 23813044
Journal: Mod Pathol. 2014 Jan;27(1):145-55.
Title: Distinct patterns of DNA methylation in conventional adenomas involving the right and left colon.
Author: Koestler, Devin C|Li, Jing|Baron, John A|Tsongalis, Gregory J|Butterly, Lynn F|Goodrich, Martha|Lesseur, Corina|Karagas, Margaret R|Marsit, Carmen J|Moore, Jason H|Andrew, Angeline S|Srivastava, Amitabh
PMID: 23868178
Journal: Int J Cancer. 2014 May 15;134(10):2342-51.
Title: Possible role of Cdx2 in the serrated pathway of colorectal cancer characterized by BRAF mutation, high-level CpG Island methylator phenotype and mismatch repair-deficiency.
Author: Dawson, Heather|Galvan, Jose A|Helbling, Melina|Muller, Dominique-Elisabeth|Karamitopoulou, Eva|Koelzer, Viktor H|Economou, Mary|Hammer, Caroline|Lugli, Alessandro|Zlobec, Inti
PMID: 24166180
Journal: Int J Colorectal Dis. 2014 Feb;29(2):217-23.
Title: Colonoscopy as a tool for evaluating colorectal tumor development in a mouse model.
Author: Adachi, Tomohiro|Hinoi, Takao|Sasaki, Yuu|Niitsu, Hiroaki|Saito, Yasuhumi|Miguchi, Masashi|Shimomura, Manabu|Ohdan, Hideki
PMID: 24212401
Journal: Arch Pathol Lab Med. 2014 Aug;138(8):1015-26.
Title: Cadherin-17 and SATB2 are sensitive and specific immunomarkers for medullary carcinoma of the large intestine.
Author: Lin, Fan|Shi, Jianhui|Zhu, Shaobo|Chen, Zongming|Li, Aihua|Chen, Taiying|Wang, Hanlin L|Liu, Haiyan
PMID: 24437456
Journal: Carcinogenesis. 2014 May;35(5):1185-92.
Title: Involvement of CDX2 in the cross talk between TNF-alpha and Wnt signaling pathway in the colon cancer cell line Caco-2.
Author: Coskun, Mehmet|Olsen, Anders Kruger|Bzorek, Michael|Holck, Susanne|Engel, Ulla Hojholt|Nielsen, Ole Haagen|Troelsen, Jesper Thorvald
PMID: 24501326
Journal: Electrophoresis. 2014 May;35(10):1504-8.
Title: Highly sensitive detection of cancer cells based on the DNA barcode assay and microcapillary electrophoretic analysis.
Author: Chung, Soyi|Cho, Minkyung|Hwan Jung, Jae|Seok Seo, Tae
PMID: 24615960
Journal: Exp Toxicol Pathol. 2014 Aug;66(5-6):235-42.
Title: Characterization of azoxymethane-induced colon tumor metastasis to lung in a mouse model relevant to human sporadic colorectal cancer and evaluation of grape seed extract efficacy.
Author: Derry, Molly M|Raina, Komal|Agarwal, Rajesh|Agarwal, Chapla
PMID: 24670932
Journal: Int J Clin Exp Pathol. 2014 Feb 15;7(3):1266-74. eCollection 2014.
Title: Pulmonary enteric adenocarcinoma: a study of the clinicopathologic and molecular status of nine cases.
Author: Wang, Cai-Xia|Liu, Biao|Wang, Yan-Fen|Zhang, Ru-Song|Yu, Bo|Lu, Zhen-Feng|Shi, Qun-Li|Zhou, Xiao-Jun
PMID: 24696747
Journal: Case Rep Oncol Med. 2014;2014:948908.
Title: Primary malignant mixed mullerian mesodermal tumor mimicking a rectosigmoid carcinoma: a case report and review of the literature.
Author: Kapur, Sakshi|Miles, Levin
PMID: 24716055
Journal: World J Gastroenterol. 2014 Apr 21;20(15):4230-43.
Title: Molecular and prognostic heterogeneity of microsatellite-unstable colorectal cancer.
Author: Kim, Jung Ho|Kang, Gyeong Hoon
PMID: 24764661
Journal: Mol Biol Rep. 2014 Aug;41(8):5375-84.
Title: RSPO fusion transcripts in colorectal cancer in Japanese population.
Author: Shinmura, Kazuya|Kahyo, Tomoaki|Kato, Hisami|Igarashi, Hisaki|Matsuura, Shun|Nakamura, Satoki|Kurachi, Kiyotaka|Nakamura, Toshio|Ogawa, Hiroshi|Funai, Kazuhito|Tanahashi, Masayuki|Niwa, Hiroshi|Sugimura, Haruhiko
PMID: 24847761
Journal: BMC Surg. 2014 May 21;14:31.
Title: Urethral metastasis from a sigmoid colon carcinoma: a quite rare case report and review of the literature.
Author: Kazama, Shinsuke|Kitayama, Joji|Sunami, Eiji|Niimi, Aya|Nomiya, Akira|Homma, Yukio|Watanabe, Toshiaki
PMID: 24884559
Journal: Hum Pathol. 2014 Aug;45(8):1704-12.
Title: BRAF-mutated microsatellite stable colorectal carcinoma: an aggressive adenocarcinoma with reduced CDX2 and increased cytokeratin 7 immunohistochemical expression.
Author: Landau, Michael S|Kuan, Shih-Fan|Chiosea, Simon|Pai, Reetesh K
PMID: 24908142
Journal: PLoS One. 2014 Jun 12;9(6):e99449.
Title: Modified-chitosan/siRNA nanoparticles downregulate cellular CDX2 expression and cross the gastric mucus barrier.
Author: Sadio, Ana|Gustafsson, Jenny K|Pereira, Bruno|Gomes, Carla Pereira|Hansson, Gunnar C|David, Leonor|Pego, Ana Paula|Almeida, Raquel
PMID: 24925340
Journal: Saudi J Gastroenterol. 2014 May-Jun;20(3):188-94.
Title: Expression of hippo pathway in colorectal cancer.
Author: Liang, Kun|Zhou, Guangxi|Zhang, Qi|Li, Jing|Zhang, Cuiping
PMID: 24976283
Journal: PLoS One. 2014 Aug 7;9(8):e104293.
Title: A novel CDX2 isoform regulates alternative splicing.
Author: Witek, Matthew E|Snook, Adam E|Lin, Jieru E|Blomain, Erik S|Xiang, Bo|Magee, Michael S|Waldman, Scott A
PMID: 25101906
Journal: Surg Oncol. 2014 Sep;23(3):167-76.
Title: The clinical perspectives of CDX2 expression in colorectal cancer: a qualitative systematic review.
Author: Olsen, J|Espersen, M L M|Jess, P|Kirkeby, L T|Troelsen, J T
PMID: 25126956
Journal: Cell Rep. 2014 Aug 21;8(4):983-90.
Title: A polymorphic enhancer near GREM1 influences bowel cancer risk through differential CDX2 and TCF7L2 binding.
Author: Lewis, Annabelle|Freeman-Mills, Luke|de la Calle-Mustienes, Elisa|Giraldez-Perez, Rosa Maria|Davis, Hayley|Jaeger, Emma|Becker, Martin|Hubner, Nina C|Nguyen, Luan N|Zeron-Medina, Jorge|Bond, Gareth|Stunnenberg, Hendrik G|Carvajal, Jaime J|Gomez-Skarmeta,
PMID: 25131200
Journal: J Biol Chem. 2014 Oct 10;289(41):28421-32.
Title: Transcriptional regulation of the intestinal nuclear bile acid farnesoid X receptor (FXR) by the caudal-related homeobox 2 (CDX2).
Author: Modica, Salvatore|Cariello, Marica|Morgano, Annalisa|Gross, Isabelle|Vegliante, Maria Carmela|Murzilli, Stefania|Salvatore, Lorena|Freund, Jean-Noel|Sabba, Carlo|Moschetta, Antonio
PMID: 25138215
Journal: PLoS One. 2014 Sep 17;9(9):e107905.
Title: Epigenetic mechanisms underlying the dynamic expression of cancer-testis genes, PAGE2, -2B and SPANX-B, during mesenchymal-to-epithelial transition.
Author: Yilmaz-Ozcan, Sinem|Sade, Asli|Kucukkaraduman, Baris|Kaygusuz, Yasemin|Senses, Kerem Mert|Banerjee, Sreeparna|Gure, Ali Osmay
PMID: 25229454
Journal: Nihon Shokakibyo Gakkai Zasshi. 2014 Oct;111(10):1983-9.
Title: [Disappearance of a gastric lesion following modified FOLFOX6 chemotherapy in a patient with metastatic colorectal cancer: a case report and literature review].
Author: Iino, Chikara|Mikami, Tatsuya|Sawaya, Manabu|Yoshida, Kenta|Aihara, Tomoyuki|Yamagata, Ryo|Sakamoto, Juichi|Tono, Hiroshi|Tanaka, Masanori|Fukuda, Shinsaku
PMID: 25283227
Journal: J Biol Chem. 2014 Nov 28;289(48):33343-54.
Title: Cdx1 and Cdx2 function as tumor suppressors.
Author: Hryniuk, Alexa|Grainger, Stephanie|Savory, Joanne G A|Lohnes, David
PMID: 25320087
Journal: Appl Immunohistochem Mol Morphol. 2014 Nov-Dec;22(10):728-34.
Title: LEF-1 is frequently expressed in colorectal carcinoma and not in other gastrointestinal tract adenocarcinomas: an immunohistochemical survey of 602 gastrointestinal tract neoplasms.
Author: Kermanshahi, Taher R|Jayachandran, Priya|Chang, Daniel T|Pai, Reet
PMID: 25394300
Journal: PLoS One. 2014 Nov 25;9(11):e113071.
Title: Predictive gene signatures: molecular markers distinguishing colon adenomatous polyp and carcinoma.
Author: Drew, Janice E|Farquharson, Andrew J|Mayer, Claus Dieter|Vase, Hollie F|Coates, Philip J|Steele, Robert J|Carey, Francis A
PMID: 25423035
Journal: Int J Surg Case Rep. 2014;5(12):979-83.
Title: A case of clear cell adenocarcinoma arising from endometriosis of the rectum treated by laparoscopic surgery.
Author: Okazawa, Yu|Takahashi, Rina|Mizukoshi, Kosuke|Takehara, Kazuhiro|Ishiyama, Shun|Sugimoto, Kiichi|Takahashi, Makoto|Kojima, Yutaka|Goto, Michitoshi|Okuzawa, Atsushi|Tomiki, Yuichi|Yao, Takashi|Sakamoto, Kazuhiro
PMID: 25460452
Journal: Hum Exp Toxicol. 2015 Jan;34(1):56-64.
Title: Silibinin modulates caudal-type homeobox transcription factor (CDX2), an intestine specific tumor suppressor to abrogate colon cancer in experimental rats.
Author: Sangeetha, N|Nalini, N
PMID: 24740923
Journal: Clin Exp Med. 2015 Aug;15(3):343-50.
Title: Chemoprevention of esophageal adenocarcinoma in a rat model by ursodeoxycholic acid.
Author: Ojima, Eisuke|Fujimura, Takashi|Oyama, Katsunobu|Tsukada, Tomoya|Kinoshita, Jun|Miyashita, Tomoharu|Tajima, Hidehiro|Fushida, Sachio|Harada, Shin-ichi|Mukaisho, Ken-ichi|Hattori, Takanori|Ohta, Tetsuo
PMID: 25034655
Journal: Mod Pathol. 2015 Feb;28(2):268-78.
Title: Aberrant expression of annexin A10 is closely related to gastric phenotype in serrated pathway to colorectal carcinoma.
Author: Tsai, Jia-Huei|Lin, Yu-Lin|Cheng, Yi-Chen|Chen, Chien-Chuan|Lin, Liang-In|Tseng, Li-Hui|Cheng, Mei-Ling|Liau, Jau-Yu|Jeng, Yung-Ming
PMID: 25081749
Journal: Cancer Res. 2015 Jan 1;75(1):216-29.
Title: B-Raf inhibitors induce epithelial differentiation in BRAF-mutant colorectal cancer cells.
Author: Herr, Ricarda|Kohler, Martin|Andrlova, Hana|Weinberg, Florian|Moller, Yvonne|Halbach, Sebastian|Lutz, Lisa|Mastroianni, Justin|Klose, Martin|Bittermann, Nicola|Kowar, Silke|Zeiser, Robert|Olayioye, Monilola A|Lassmann, Silke|Busch, Hauke|Boerries, Melanie
PMID: 25381152
Journal: World J Gastroenterol. 2015 Feb 7;21(5):1436-43.
Title: Extending the functions of the homeotic transcription factor Cdx2 in the digestive system through nontranscriptional activities.
Author: Freund, Jean-Noel|Duluc, Isabelle|Reimund, Jean-Marie|Gross, Isabelle|Domon-Dell, Claire
PMID: 25663763
Journal: World J Gastroenterol. 2015 Feb 7;21(5):1457-67.
Title: Loss of CDX2 expression is associated with poor prognosis in colorectal cancer patients.
Author: Bae, Jeong Mo|Lee, Tae Hun|Cho, Nam-Yun|Kim, Tae-You|Kang, Gyeong Hoon
PMID: 25663765
Journal: Hum Pathol. 2015 May;46(5):643-56.
Title: Gastric-type expression signature in serrated pathway-associated colorectal tumors.
Author: Kim, Jung Ho|Kim, Kyung-Ju|Rhee, Ye-Young|Bae, Jeong Mo|Cho, Nam-Yun|Lee, Hye Seung|Kang, Gyeong Hoon
PMID: 25704805
Journal: Mol Med Rep. 2015 Aug;12(2):1838-44.
Title: Recombinant lentivirus with enhanced expression of caudal-related homeobox protein 2 inhibits human colorectal cancer cell proliferation in vitro.
Author: He, Sai|Sun, Xue-Jun|Zheng, Jian-Bao|Qi, Jie|Chen, Nan-Zheng|Wang, Wei|Wei, Guang-Bing|Liu, Dong|Yu, Jun-Hui|Lu, Shao-Ying|Wang, Hui
PMID: 25847407
Journal: Mol Med Rep. 2015 Sep;12(3):3409-3415.
Title: Overexpression of caudal-related homeobox transcription factor 2 inhibits the growth of transplanted colorectal tumors in nude mice.
Author: Zheng, Jian-Bao|Qiao, Li-Na|Sun, Xue-Jun|Qi, Jie|Ren, Hai-Liang|Wei, Guang-Bing|Zhou, Pei-Hua|Yao, Jian-Feng|Zhang, Li|Jia, Peng-Bo
PMID: 26005051
Journal: Ann Diagn Pathol. 2015 Aug;19(4):249-52.
Title: The value of SATB2 in the differential diagnosis of intestinal-type mucinous tumors of the ovary: primary vs metastatic.
Author: Perez Montiel, Delia|Arispe Angulo, Karen|Cantu-de Leon, David|Bornstein Quevedo, Leticia|Chanona Vilchis, Jose|Herrera Montalvo, Luis
PMID: 26059401
Journal: Biochim Biophys Acta. 2015 Aug;1849(8):1066-80.
Title: MicroRNA-196b is transcribed from an autonomous promoter and is directly regulated by Cdx2 and by posterior Hox proteins during embryogenesis.
Author: Fantini, Sebastian|Salsi, Valentina|Vitobello, Antonio|Rijli, Filippo M|Zappavigna, Vincenzo
PMID: 26141604
Journal: Oncotarget. 2015 Oct 13;6(31):30993-1006.
Title: Achaete scute-like 2 suppresses CDX2 expression and inhibits intestinal neoplastic epithelial cell differentiation.
Author: Shang, Yangyang|Pan, Qiong|Chen, Lei|Ye, Jun|Zhong, Xiaoli|Li, Xiaohuan|Meng, Linkuan|Guo, Jin|Tian, Yin|He, Yonghong|Chen, Wensheng|Peng, Zhihong|Wang, Rongquan
PMID: 26307678
Journal: Pol J Pathol. 2015 Sep;66(3):246-53.
Title: Relationship among mismatch repair deficiency, CDX2 loss, p53 and E-cadherin in colon carcinoma and suitability of using a double panel of mismatch repair proteins by immunohistochemistry.
Author: Sayar, Ilyas|Akbas, Emin Murat|Isik, Arda|Gokce, Aysun|Peker, Kemal|Demirtas, Levent|Gurbuzel, Mehmet
PMID: 26619103
Journal: Sci Rep. 2015 Dec 3;5:17568.
Title: TET-catalyzed 5-hydroxymethylcytosine regulates gene expression in differentiating colonocytes and colon cancer.
Author: Chapman, Christopher G|Mariani, Christopher J|Wu, Feng|Meckel, Katherine|Butun, Fatma|Chuang, Alice|Madzo, Jozef|Bissonette, Marc B|Kwon, John H|Godley, Lucy A
PMID: 26631571
Journal: Clin Epigenetics. 2015 Dec 16;7:129.
Title: MicroRNA profiling of primary pulmonary enteric adenocarcinoma in members from the same family reveals some similarities to pancreatic adenocarcinoma-a step towards personalized therapy.
Author: Garajova, Ingrid|Funel, Niccola|Fiorentino, Michelangelo|Agostini, Valentina|Ferracin, Manuela|Negrini, Massimo|Frassineti, Giovanni Luca|Gavelli, Giampaolo|Frampton, Adam Enver|Biasco, Guido|Giovannetti, Elisa
PMID: 26677401
Journal: Gan To Kagaku Ryoho. 2015 Nov;42(12):1662-4.
Title: [A Case of Sigmoid Colon Cancer with Metastasis to the Uterus].
Author: Tokoro, Yukinari|Tonooka, Toru|Souda, Hiroaki|Takiguchi, Nobuhiro|Chibana, Tomofumi|Kobayashi, Ryosuke|Arimitsu, Hidehito|Yanagibashi, Hiroo|Chou, Akihiro|Ikeda, Atsushi|Nabeya, Nobuhiro|Kainuma, Osamu|Yamamoto, Hiroshi|Nagata, Matsuo
PMID: 26805130
Journal: Gan To Kagaku Ryoho. 2015 Nov;42(12):1854-6.
Title: [A Case of Surgical Resection of a Liver Metastasis from Colorectal Cancer with a Macroscopic Portal Vein Tumor Thrombus].
Author: Sasaki, Kazuki|Tomimaru, Yoshito|Wada, Hiroshi|Ogawa, Hisataka|Yamada, Daisaku|Tomokuni, Akira|Asaoka, Tadafumi|Noda, Takehiro|Gotoh, Kunihito|Kawamoto, Koichi|Marubashi, Shigeru|Eguchi, Hidetoshi|Nagano, Hiroaki|Doki, Yuichiro|Mori, Masaki
PMID: 26805195
Journal: Eur J Cancer Prev. 2016 Jan;25(1):85-96.
Title: Meta-analysis on vitamin D receptor and cancer risk: focus on the role of TaqI, ApaI, and Cdx2 polymorphisms.
Author: Serrano, Davide|Gnagnarella, Patrizia|Raimondi, Sara|Gandini, Sara
PMID: 25738688
Journal: Hum Pathol. 2016 Jan;47(1):85-94.
Title: Are clinicopathological features of colorectal cancers with methylation in half of CpG island methylator phenotype panel markers different from those of CpG island methylator phenotype-high colorectal cancers?
Author: Bae, Jeong Mo|Rhee, Ye-Young|Kim, Kyung Ju|Wen, Xianyu|Song, Young Seok|Cho, Nam-Yun|Kim, Jung Ho|Kang, Gyeong Hoon
PMID: 26520418
Journal: Exp Mol Pathol. 2016 Feb;100(1):59-66.
Title: CDX2 downregulation is associated with poor differentiation and MMR deficiency in colon cancer.
Author: Olsen, J|Eiholm, S|Kirkeby, L T|Espersen, M L M|Jess, P|Gogenur, I|Olsen, J|Troelsen, J T
PMID: 26551082
Journal: Clin Res Hepatol Gastroenterol. 2016 Sep;40(4):487-93.
Title: Sulfasalazine, a therapeutic agent for ulcerative colitis, inhibits the growth of CD44v9(+) cancer stem cells in ulcerative colitis-related cancer.
Author: Seishima, Ryo|Okabayashi, Koji|Nagano, Osamu|Hasegawa, Hirotoshi|Tsuruta, Masashi|Shimoda, Masayuki|Kameyama, Kaori|Saya, Hideyuki|Kitagawa, Yuko
PMID: 26775891
Journal: N Engl J Med. 2016 Jan 21;374(3):211-22.
Title: CDX2 as a Prognostic Biomarker in Stage II and Stage III Colon Cancer.
Author: Dalerba, Piero|Sahoo, Debashis|Paik, Soonmyung|Guo, Xiangqian|Yothers, Greg|Song, Nan|Wilcox-Fogel, Nate|Forgo, Erna|Rajendran, Pradeep S|Miranda, Stephen P|Hisamori, Shigeo|Hutchison, Jacqueline|Kalisky, Tomer|Qian, Dalong|Wolmark, Norman|Fisher, George
PMID: 26789870
Journal: World J Surg Oncol. 2016 Jan 25;14(1):22.
Title: Cytokeratin 7-positive/cytokeratin 20-negative cecal adenocarcinoma metastatic to the uterine cervix: a case report.
Author: Toyoshima, Masafumi|Momono, Yuta|Makino, Hiromitsu|Kudo, Takako|Oka, Naomi|Sakurada, Junko|Suzuki, Hiroyoshi|Kodama, Hideaki|Yoshinaga, Kosuke
PMID: 26810414
Journal: Cancer Biol Ther. 2016 Apr 2;17(4):430-8.
Title: Identifying cancer origin using circulating tumor cells.
Author: Lu, Si-Hong|Tsai, Wen-Sy|Chang, Ying-Hsu|Chou, Teh-Ying|Pang, See-Tong|Lin, Po-Hung|Tsai, Chun-Ming|Chang, Ying-Chih
PMID: 26828696
Journal: Cell Stem Cell. 2016 Feb 4;18(2):168-9.
Title: CDX2: Linking Cell and Patient Fates in Colon Cancer.
Author: Fearon, Eric R|Huang, Emina H
PMID: 26849302
Journal: Cancer Lett. 2016 May 1;374(2):208-15.
Title: Distinct mechanisms for opposite functions of homeoproteins Cdx2 and HoxB7 in double-strand break DNA repair in colon cancer cells.
Author: Soret, Christine|Martin, Elisabeth|Duluc, Isabelle|Dantzer, Francoise|Vanier, Marie|Gross, Isabelle|Freund, Jean-Noel|Domon-Dell, Claire
PMID: 26902420
Journal: Oncotarget. 2016 Apr 5;7(14):17870-84.
Title: Chemopreventive activity of GEN-27, a genistein derivative, in colitis-associated cancer is mediated by p65-CDX2-beta-catenin axis.
Author: Du, Qianming|Wang, Yajing|Liu, Chao|Wang, Hong|Fan, Huimin|Li, Yan|Wang, Jianing|Zhang, Xu|Lu, Jinrong|Ji, Hui|Hu, Rong
PMID: 26910375
Journal: Cancer Med. 2016 Jul;5(7):1546-55.
Title: Regulation of multidrug resistance 1 expression by CDX2 in ovarian mucinous adenocarcinoma.
Author: Koh, Iemasa|Hinoi, Takao|Sentani, Kazuhiro|Hirata, Eiji|Nosaka, Suguru|Niitsu, Hiroaki|Miguchi, Masashi|Adachi, Tomohiro|Yasui, Wataru|Ohdan, Hideki|Kudo, Yoshiki
PMID: 27060927
Journal: Virchows Arch. 2016 Aug;469(2):135-44.
Title: Immunohistochemical staining for p16 and BRAFV600E is useful to distinguish between sporadic and hereditary (Lynch syndrome-related) microsatellite instable colorectal carcinomas.
Author: Boissiere-Michot, Florence|Frugier, Helene|Ho-Pun-Cheung, Alexandre|Lopez-Crapez, Evelyne|Duffour, Jacqueline|Bibeau, Frederic
PMID: 27220764
Journal: N Engl J Med. 2016 Jun 2;374(22):2184.
Title: CDX2 as a Prognostic Biomarker in Colon Cancer.
Author: Dalerba, Piero|Sahoo, Debashis|Clarke, Michael F
PMID: 27248627
Journal: N Engl J Med. 2016 Jun 2;374(22):2182.
Title: CDX2 as a Prognostic Biomarker in Colon Cancer.
Author: Coebergh van den Braak, Robert R J|Martens, John W M|Ijzermans, Jan N M
PMID: 27248628
Journal: N Engl J Med. 2016 Jun 2;374(22):2183.
Title: CDX2 as a Prognostic Biomarker in Colon Cancer.
Author: Schirripa, Marta|Loupakis, Fotios|Lenz, Heinz-Josef
PMID: 27248629
Journal: N Engl J Med. 2016 Jun 2;374(22):2183-4.
Title: CDX2 as a Prognostic Biomarker in Colon Cancer.
Author: Chiche, Laurent|Rinchai, Darawan|Chaussabel, Damien
PMID: 27248630
Journal: Oncotarget. 2016 Jul 5;7(27):42099-42109.
Title: Lack of interferon-gamma receptor results in a microenvironment favorable for intestinal tumorigenesis.
Author: Zhang, Caibo|Hou, Dong|Wei, Haifeng|Zhao, Minnan|Yang, Lin|Liu, Qiao|Zhang, Xiyu|Gong, Yaoqin|Shao, Changshun
PMID: 27286456
Journal: Oncol Lett. 2016 Jul;12(1):257-261.
Title: Synchronous ovarian metastasis from colorectal cancer: A report of two cases.
Author: Shimazaki, Jiro|Tabuchi, Takanobu|Nishida, Kiyotaka|Takemura, Akira|Motohashi, Gyo|Kajiyama, Hideki|Suzuki, Shuji
PMID: 27347134
Journal: BMC Cancer. 2016 Jul 13;16:471.
Title: SOX2 expression is associated with a cancer stem cell state and down-regulation of CDX2 in colorectal cancer.
Author: Lundberg, Ida V|Edin, Sofia|Eklof, Vincy|Oberg, Ake|Palmqvist, Richard|Wikberg, Maria L
PMID: 27411517
Journal: Case Rep Pathol. 2016;2016:4704781.
Title: Intrabiliary Hepatic Metastasis of Colorectal Carcinoma Mimicking Primary Cholangiocarcinoma: A Case Report and Review of the Literature.
Author: Dong, Yimin|Patel, Hitendra|Patel, Charmi
PMID: 27429820
Journal: Mol Cancer Res. 2016 Nov;14(11):1097-1109.
Title: Ubiquitin Ligase, Fbw7, Targets CDX2 for Degradation via Two Phosphodegron Motifs in a GSK3beta-Dependent Manner.
Author: Kumar, Yogesh|Shukla, Nidhi|Thacker, Gatha|Kapoor, Isha|Lochab, Savita|Bhatt, Madan Lal Brahma|Chattopadhyay, Naibedya|Sanyal, Sabyasachi|Trivedi, Arun Kumar
PMID: 27470268
Journal: Biochim Biophys Acta. 2016 Nov;1859(11):1353-1367.
Title: Enhancer decommissioning by Snail1-induced competitive displacement of TCF7L2 and down-regulation of transcriptional activators results in EPHB2 silencing.
Author: Schnappauf, Oskar|Beyes, Sven|Dertmann, Annika|Freihen, Vivien|Frey, Patrick|Jagle, Sabine|Rose, Katja|Michoel, Tom|Grosschedl, Rudolf|Hecht, Andreas
PMID: 27504909
Journal: Pathologe. 2016 Nov;37(Suppl 2):186-190.
Title: [Pathogenetic aspects in precursor lesions of gastrointestinal tumors].
Author: Rau, T
PMID: 27638535
Journal: World J Gastroenterol. 2016 Oct 7;22(37):8247-8256.
Title: Impact of homeobox genes in gastrointestinal cancer.
Author: Joo, Moon Kyung|Park, Jong-Jae|Chun, Hoon Jai
PMID: 27729732
Journal: Genet Test Mol Biomarkers. 2016 Nov;20(11):710-714.
Title: Methylation of CDX2 as a Predictor in Poor Clinical Outcome of Patients with Colorectal Cancer.
Author: Jiang, Guozhong|Luo, Chenglin|Sun, Miaomiao|Zhao, Zhihua|Li, Wencai|Chen, Kuisheng|Fan, Tianli
PMID: 27754705
Journal: Int J Surg Case Rep. 2016;29:133-136.
Title: A case report of chylous ascites after gastric bypass for morbid obesity.
Author: Capristo, Esmeralda|Spuntarelli, Valerio|Treglia, Giorgio|Arena, Vincenzo|Giordano, Alessandro|Mingrone, Geltrude
PMID: 27846453
Journal: Oncol Lett. 2016 Nov;12(5):3229-3233.
Title: Methylation of promoter region of CDX2 gene in colorectal cancer.
Author: Wang, Yunshuai|Li, Zhaohui|Li, Wenxian|Liu, Shuaifeng|Han, Baowei
PMID: 27899987
Journal: Gan To Kagaku Ryoho. 2016 Nov;43(12):2047-2049.
Title: [Right Hemi-Colectomy for a Metastatic Transverse Colon Tumor from Breast Cancer Following Bilateral Breast Cancer Resection - A Case Report].
Author: Okamura, Shu|Yanagisawa, Tetsu|Ohishi, Kazuhito|Murata, Kohei|Nushijima, Yoichiro|Hamano, Rie|Fukuchi, Nariaki|Ebisui, Chikara|Yokouchi, Hideoki|Kinuta, Masakatsu
PMID: 28133217
Journal: Clin Cancer Res. 2017 Jan 15;23(2):387-398.
Title: Practical and Robust Identification of Molecular Subtypes in Colorectal Cancer by Immunohistochemistry.
Author: Trinh, Anne|Trumpi, Kari|De Sousa E Melo, Felipe|Wang, Xin|de Jong, Joan H|Fessler, Evelyn|Kuppen, Peter J K|Reimers, Marlies S|Swets, Marloes|Koopman, Miriam|Nagtegaal, Iris D|Jansen, Marnix|Hooijer, Gerrit K J|Offerhaus, George J A|Kranenburg, Onno|Punt
PMID: 27459899
Journal: Mod Pathol. 2017 Feb;30(2):267-277.
Title: Downregulation of acetyl-CoA synthetase 2 is a metabolic hallmark of tumor progression and aggressiveness in colorectal carcinoma.
Author: Bae, Jeong Mo|Kim, Jung Ho|Oh, Hyeon Jeong|Park, Hye Eun|Lee, Tae Hun|Cho, Nam-Yun|Kang, Gyeong Hoon
PMID: 27713423
Journal: Mod Pathol. 2017 Feb;30(2):278-285.
Title: Clinicopathologic profile, immunophenotype, and genotype of CD274 (PD-L1)-positive colorectal carcinomas.
Author: Inaguma, Shingo|Lasota, Jerzy|Wang, Zengfeng|Felisiak-Golabek, Anna|Ikeda, Hiroshi|Miettinen, Markku
PMID: 27813511
Journal: Cancer Lett. 2017 Feb 1;386:57-64.
Title: The tumor suppressor CDX2 opposes pro-metastatic biomechanical modifications of colon cancer cells through organization of the actin cytoskeleton.
Author: Platet, Nadine|Hinkel, Isabelle|Richert, Ludovic|Murdamoothoo, Devadarssen|Moufok-Sadoun, Ahlam|Vanier, Marie|Lavalle, Philippe|Gaiddon, Christian|Vautier, Dominique|Freund, Jean-Noel|Gross, Isabelle
PMID: 27816490
Journal: Cell Death Differ. 2017 Mar;24(3):458-468.
Title: Ketogenesis contributes to intestinal cell differentiation.
Author: Wang, Qingding|Zhou, Yuning|Rychahou, Piotr|Fan, Teresa W-M|Lane, Andrew N|Weiss, Heidi L|Evers, B Mark
PMID: 27935584
Journal: Elife. 2017 Jan 10;6.
Title: BRAF(V600E) cooperates with CDX2 inactivation to promote serrated colorectal tumorigenesis.
Author: Sakamoto, Naoya|Feng, Ying|Stolfi, Carmine|Kurosu, Yuki|Green, Maranne|Lin, Jeffry|Green, Megan E|Sentani, Kazuhiro|Yasui, Wataru|McMahon, Martin|Hardiman, Karin M|Spence, Jason R|Horita, Nobukatsu|Greenson, Joel K|Kuick, Rork|Cho, Kathleen R|Fearon, Eric
PMID: 28072391
Journal: J Pathol Clin Res. 2017 Jan 13;3(1):58-70.
Title: Construction and analysis of tissue microarrays in the era of digital pathology: a pilot study targeting CDX1 and CDX2 in a colon cancer cohort of 612 patients.
Author: Nolte, Sarah|Zlobec, Inti|Lugli, Alessandro|Hohenberger, Werner|Croner, Roland|Merkel, Susanne|Hartmann, Arndt|Geppert, Carol I|Rau, Tilman T
PMID: 28138402
Journal: Intern Med. 2017;56(3):301-305.
Title: Pancreatic Metastasis from Rectal Cancer that was Diagnosed by Endoscopic Ultrasonography-guided Fine Needle Aspiration (EUS-FNA).
Author: Sano, Itsuki|Katanuma, Akio|Yane, Kei|Kin, Toshifumi|Nagai, Kazumasa|Yamazaki, Hajime|Koga, Hideaki|Kitagawa, Koh|Yokoyama, Kensuke|Ikarashi, Satoshi|Takahashi, Kuniyuki|Maguchi, Hiroyuki|Omori, Yuko|Shinohara, Toshiya
PMID: 28154274
Journal: Histopathology. 2017 Jul;71(1):34-41.
Title: A33 shows similar sensitivity to but is more specific than CDX2 as an immunomarker of colorectal carcinoma.
Author: Wong, Newton A C S|Adamczyk, Lukasz A|Evans, Shanna|Cullen, Jayne|Oniscu, Anca|Oien, Karin A
PMID: 28226180
Journal: Ann Oncol. 2017 May 1;28(5):1032-1035.
Title: CDX2 prognostic value in stage II/III resected colon cancer is related to CMS classification.
Author: Pilati, C|Taieb, J|Balogoun, R|Marisa, L|de Reynies, A|Laurent-Puig, P
PMID: 28328000
Journal: Anticancer Res. 2017 Apr;37(4):1563-1568.
Title: Detection of Free Cancer Cells in Pelvic Lavage with Double Immunocytochemistry at Rectal Cancer Surgery.
Author: Kindler, Csaba|Smedh, Kenneth|Chabok, Abbas|Shetye, Jayant|Dafnis, George|Nikberg, Maziar
PMID: 28373415
Journal: J Clin Oncol. 2017 Jun 1;35(16):1836-1844.
Title: Aspirin Use and Colorectal Cancer Survival According to Tumor CD274 (Programmed Cell Death 1 Ligand 1) Expression Status.
Author: Hamada, Tsuyoshi|Cao, Yin|Qian, Zhi Rong|Masugi, Yohei|Nowak, Jonathan A|Yang, Juhong|Song, Mingyang|Mima, Kosuke|Kosumi, Keisuke|Liu, Li|Shi, Yan|da Silva, Annacarolina|Gu, Mancang|Li, Wanwan|Keum, NaNa|Zhang, Xuehong|Wu, Kana|Meyerhardt, Jeffrey A|Giova
PMID: 28406723
Journal: Diagn Pathol. 2017 May 12;12(1):39.
Title: Intestinal differentiated mucinous adenocarcinoma of the endometrium with sporadic MSI high status: a case report.
Author: Trippel, Mafalda|Imboden, Sara|Papadia, Andrea|Mueller, Michael D|Mertineit, Nando|Harma, Kirsi|Nicolae, Alina|Vassella, Erik|Rau, Tilman T
PMID: 28494767
Journal: Target Oncol. 2017 Jun;12(3):265-275.
Title: What We Know About Stage II and III Colon Cancer: It's Still Not Enough.
Author: Puccini, Alberto|Berger, Martin D|Zhang, Wu|Lenz, Heinz-Josef
PMID: 28504299
Journal: Biochim Biophys Acta Mol Basis Dis. 2017 Sep;1863(9):2126-2134.
Title: Reelin protects from colon pathology by maintaining the intestinal barrier integrity and repressing tumorigenic genes.
Author: Carvajal, Ana E|Serrano-Morales, Jose M|Vazquez-Carretero, Maria D|Garcia-Miranda, Pablo|Calonge, Maria L|Peral, Maria J|Ilundain, Anunciacion A
PMID: 28572005
Journal: PLoS One. 2017 Jun 19;12(6):e0178760.
Title: A multidimensional integration analysis reveals potential bridging targets in the process of colorectal cancer liver metastasis.
Author: Gao, Bo|Yu, Tian|Xue, Dongbo|Sun, Boshi|Shao, Qin|Choudhry, Hani|Marcus, Victoria|Ragoussis, Jiannis|Zhang, Yuguo|Zhang, Weihui|Gao, Zu-Hua
PMID: 28628609
Journal: Surg Case Rep. 2017 Dec;3(1):84.
Title: Resection of rectal cancer resembling submucosal tumor that was preoperatively diagnosed with endoscopic ultrasound-guided biopsy.
Author: Tanio, Akimitsu|Saito, Hiroaki|Ashida, Keigo|Urushibara, Shouichi|Yamamoto, Manabu|Tokuyasu, Naruo|Sakamoto, Teruhisa|Honjo, Soichiro|Maeta, Yoshihiko|Fujiwara, Yoshiyuki
PMID: 28748455
Journal: Case Rep Oncol Med. 2017;2017:2321052.
Title: Are All Mutations the Same? A Rare Case Report of Coexisting Mutually Exclusive KRAS and BRAF Mutations in a Patient with Metastatic Colon Adenocarcinoma.
Author: Vittal, Anusha|Middinti, Akshay|Kasi Loknath Kumar, Anup
PMID: 28811946
Journal: Dtsch Med Wochenschr. 2017 Nov;142(22):1652-1659.
Title: [Personalized Treatment for Colorectal Carcinomas].
Author: Stintzing, Sebastian
PMID: 29078210
Journal: J Pathol Clin Res. 2017 Oct 7;3(4):268-278.
Title: Histopathological and genotypic characterization of metastatic colorectal carcinoma with PD-L1 (CD274)-expression: Possible roles of tumour micro environmental factors for CD274 expression.
Author: Inaguma, Shingo|Lasota, Jerzy|Felisiak-Golabek, Anna|Kowalik, Artur|Wang, Zengfeng|Zieba, Sebastian|Kalisz, Joanna|Ikeda, Hiroshi|Miettinen, Markku
PMID: 29085667
Journal: J Thorac Dis. 2017 Oct;9(Suppl 12):S1282-S1290.
Title: Pulmonary metastasectomy for colorectal cancer: analysis of prognostic factors affecting survival.
Author: Ampollini, Luca|Gnetti, Letizia|Goldoni, Matteo|Viani, Lorenzo|Faedda, Elisabetta|Campanini, Nicoletta|Caruana, Pietro|Crafa, Pellegrino|Negri, Francesca|Pucci, Francesca|Leonardi, Francesco|Ventura, Luigi|Balestra, Valeria|Braggio, Cesare|Bocchialini, Gi
PMID: 29119016
Journal: PLoS Genet. 2017 Nov 20;13(11):e1007109.
Title: SNAIL1-mediated downregulation of FOXA proteins facilitates the inactivation of transcriptional enhancer elements at key epithelial genes in colorectal cancer cells.
Author: Jagle, Sabine|Busch, Hauke|Freihen, Vivien|Beyes, Sven|Schrempp, Monika|Boerries, Melanie|Hecht, Andreas
PMID: 29155818
Journal: SAGE Open Med Case Rep. 2017 Dec 5;5:2050313X17745204.
Title: Endometrioid adenocarcinoma arising from colon endometriosis.
Author: Palla, Viktoria-Varvara|Karaolanis, Georgios|Bliona, Theodora|Katafigiotis, Ioannis|Anastasiou, Ioannis|Hassiakos, Demetrios
PMID: 29238580
Journal: Arab J Gastroenterol. 2017 Dec;18(4):191-200.
Title: Simple classifiers for molecular subtypes of colorectal cancer.
Author: Kim, Woo Gyeong|Kim, Joo Yeon|Park, Do Youn
PMID: 29241727
Journal: Cell Rep. 2017 Dec 26;21(13):3833-3845.
Title: Degree of Tissue Differentiation Dictates Susceptibility to BRAF-Driven Colorectal Cancer.
Author: Tong, Kevin|Pellon-Cardenas, Oscar|Sirihorachai, Veerin R|Warder, Bailey N|Kothari, Om A|Perekatt, Ansu O|Fokas, Emily E|Fullem, Robert L|Zhou, Anbo|Thackray, Joshua K|Tran, Hiep|Zhang, Lanjing|Xing, Jinchuan|Verzi, Michael P
PMID: 29281831
Journal: Rom J Morphol Embryol. 2017;58(4):1569-1577.
Title: Long-term survival in a patient with advanced gastric cancer and metachronous right-sided colon cancer.
Author: Sava, Anca|Ciobanu Apostol, Delia Gabriela|Sapte, Elena|Ionescu, Lidia|Costea, Claudia Florida|Ciocoiu, Manuela|Dumitrescu, Gabriela Florenta|Stan, Cristinel Ionel|Slanina, Ana Maria|Cobzaru, Roxana Gabriela|Costache, Irina Iuliana
PMID: 29556659
Journal: Appl Immunohistochem Mol Morphol. 2018 Feb;26(2):140-146.
Title: The Role of SATB2 as a Diagnostic Marker of Sinonasal Intestinal-type Adenocarcinoma.
Author: Skalova, Alena|Sar, Aylin|Laco, Jan|Metelkova, Alena|Miesbauerova, Marketa|Steiner, Petr|Svajdler, Marian|Michal, Michal
PMID: 27258560
Journal: Pathol Oncol Res. 2018 Jul;24(3):609-616.
Title: Prognosis of Signet Ring Cell Carcinoma of the Colon and Rectum and their Distinction of Mucinous Adenocarcinoma with Signet Ring Cells. A Comparative Study.
Author: Pozos-Ochoa, Luis I|Lino-Silva, Leonardo S|Leon-Takahashi, Alberto M|Salcedo-Hernandez, Rosa A
PMID: 28785968
Journal: Histopathology. 2018 Feb;72(3):423-432.
Title: Clinicopathological and molecular implications of aberrant thyroid transcription factor-1 expression in colorectal carcinomas: an immunohistochemical analysis of 1319 cases using three different antibody clones.
Author: Bae, Jeong Mo|Kim, Jung Ho|Park, Jeong Hwan|Park, Hye Eun|Cho, Nam-Yun|Kang, Gyeong Hoon
PMID: 28914964
Journal: EBioMedicine. 2018 Feb;28:62-69.
Title: SATB2 is a Promising Biomarker for Identifying a Colorectal Origin for Liver Metastatic Adenocarcinomas.
Author: Zhang, Yi-Jun|Chen, Jie-Wei|He, Xiao-Sheng|Zhang, Hui-Zhong|Ling, Yi-Hong|Wen, Jia-Huai|Deng, Wei-Hao|Li, Peng|Yun, Jing-Ping|Xie, Dan|Cai, Mu-Yan
PMID: 29396302
Journal: J Exp Med. 2018 Mar 5;215(3):911-926.
Title: The Cdx2 homeobox gene suppresses intestinal tumorigenesis through non-cell-autonomous mechanisms.
Author: Balbinot, Camille|Armant, Olivier|Elarouci, Nabila|Marisa, Laetitia|Martin, Elisabeth|De Clara, Etienne|Onea, Alina|Deschamps, Jacqueline|Beck, Felix|Freund, Jean-Noel|Duluc, Isabelle
PMID: 29439001
Journal: Am J Clin Pathol. 2018 Feb 17;149(3):241-246.
Title: Dual Stain With SATB2 and CK20/Villin Is Useful to Distinguish Colorectal Carcinomas From Other Tumors.
Author: Li, Zaibo|Rock, Jonathan B|Roth, Rachel|Lehman, Amy|Marsh, William L|Suarez, Adrian|Frankel, Wendy L
PMID: 29471325
Journal: J Stomatol Oral Maxillofac Surg. 2018 Jun;119(3):229-231.
Title: A rare case of oral metastasis of colon adenocarcinoma.
Author: Romanet, I|Lan, R|Ordioni, U|Albertini, A F|Campana, F
PMID: 29475082
Journal: Appl Immunohistochem Mol Morphol. 2018 Feb 27.
Title: Clinicopathologic Significance of Intestinal-type Molecules' Expression and Different EGFR Gene Status in Pulmonary Adenocarcinoma.
Author: Feng, Chang|Feng, Man|Gao, Yujun|Zhao, Xiaogang|Peng, Chuanliang|Yang, Xiangshan|Zhang, Jing
PMID: 29489510
Journal: Oncotarget. 2018 Jan 13;9(10):8849-8869.
Title: LRP1 expression in colon cancer predicts clinical outcome.
Author: Boulagnon-Rombi, Camille|Schneider, Christophe|Leandri, Chloe|Jeanne, Albin|Grybek, Virginie|Bressenot, Aude Marchal|Barbe, Coralie|Marquet, Benjamin|Nasri, Saviz|Coquelet, Christelle|Fichel, Caroline|Bouland, Nicole|Bonnomet, Arnaud|Kianmanesh, Reza|Lebr
PMID: 29507659
Journal: Clin Colorectal Cancer. 2018 Jun;17(2):97-103.
Title: Association of CDX2 Expression With Survival in Early Colorectal Cancer: A Systematic Review and Meta-analysis.
Author: Tomasello, Gianluca|Barni, Sandro|Turati, Luca|Ghidini, Michele|Pezzica, Ezio|Passalacqua, Rodolfo|Petrelli, Fausto
PMID: 29519711
Journal: Mol Pharmacol. 2018 May;93(5):541-552.
Title: Cooperative Regulation of Intestinal UDP-Glucuronosyltransferases 1A8, -1A9, and 1A10 by CDX2 and HNF4alpha Is Mediated by a Novel Composite Regulatory Element.
Author: Mubarokah, Nurul|Hulin, Julie-Ann|Mackenzie, Peter I|McKinnon, Ross A|Haines, Alex Z|Hu, Dong Gui|Meech, Robyn
PMID: 29519853
Journal: Oncotarget. 2018 Jan 4;9(16):13068-13076.
Title: Associations between VDR gene polymorphisms and colorectal cancer susceptibility: an updated meta-analysis based on 39 case-control studies.
Author: Pan, Zhipeng|Chen, Mengya|Hu, Xingxing|Wang, Hua|Yang, Jiajia|Zhang, Congjun|Pan, Faming|Sun, Guoping
PMID: 29560132
Journal: Methods Mol Biol. 2018;1765:179-191.
Title: Classification of Colorectal Cancer in Molecular Subtypes by Immunohistochemistry.
Author: Ten Hoorn, Sanne|Trinh, Anne|de Jong, Joan|Koens, Lianne|Vermeulen, Louis
PMID: 29589308
Journal: Pathophysiology. 2018 Jun;25(2):89-99.
Title: Revisiting colorectal cancer animal model - An improved metastatic model for distal rectosigmoid colon carcinoma.
Author: Caetano-Oliveira, Rui|Gomes, Marcos Antonio|Abrantes, Ana Margarida|Tavares-Silva, Edgar|Oliveira, Marco Carvalho|Laranjo, Mafalda|Queiros, Debora Basilio|Casalta-Lopes, Joao|Pires, Salome|Carvalho, Lina|Gouveia, Rosa|Santos, Paulo Rodrigues|Priolli, Deni
PMID: 29628185
Journal: Virchows Arch. 2018 Aug;473(2):199-207.
Title: The prognostic impact of CDX2 correlates with the underlying mismatch repair status and BRAF mutational status but not with distant metastasis in colorectal cancer.
Author: Neumann, Jens|Heinemann, Volker|Engel, Jutta|Kirchner, Thomas|Stintzing, Sebastian
PMID: 29675807
Journal: Oncotarget. 2018 Mar 30;9(24):17056-17065.
Title: CDX2 expression is concordant between primary colorectal cancer lesions and corresponding liver metastases independent of chemotherapy: a single-center retrospective study in Japan.
Author: Shigematsu, Yasuyuki|Inamura, Kentaro|Mise, Yoshihiro|Saiura, Akio|Rehnberg, Emil|Yamamoto, Noriko|Ishikawa, Yuichi|Takahashi, Shunji|Kanda, Hiroaki
PMID: 29682204
Journal: Mol Oncol. 2018 Sep;12(9):1639-1655.
Title: Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer.
Author: Bruun, Jarle|Sveen, Anita|Barros, Rita|Eide, Peter W|Eilertsen, Ina|Kolberg, Matthias|Pellinen, Teijo|David, Leonor|Svindland, Aud|Kallioniemi, Olli|Guren, Marianne G|Nesbakken, Arild|Almeida, Raquel|Lothe, Ragnhild A
PMID: 29900672
Journal: APMIS. 2018 Jun;126(6):494-500.
Title: SATB2 is a supplementary immunohistochemical marker to CDX2 in the diagnosis of colorectal carcinoma metastasis in an unknown primary.
Author: Dabir, Parag Deepak|Svanholm, Hans|Christiansen, Jens Johannes
PMID: 29924451
Journal: Oncol Lett. 2018 Jul;16(1):195-198.
Title: Methylation of CDX2 gene promoter in the prediction of treatment efficacy in colorectal cancer.
Author: Wang, Yunshuai|Li, Zhaohui|Li, Wenxian|Liu, Shuaifeng|Han, Baowei
PMID: 29928401
Journal: Am J Surg Pathol. 2018 Oct;42(10):1409-1417.
Title: Loss of SATB2 Expression in Colorectal Carcinoma Is Associated With DNA Mismatch Repair Protein Deficiency and BRAF Mutation.
Author: Ma, Changqing|Olevian, Dane C|Lowenthal, Brett M|Jayachandran, Priya|Kozak, Margaret M|Chang, Daniel T|Pai, Reetesh K
PMID: 30001238
Journal: Anticancer Res. 2018 Aug;38(8):4847-4852.
Title: Sigmoid Colon Adenocarcinoma with Isolated Loss of PMS2 Presenting in a Patient with Synchronous Prostate Cancer with Intact MMR: Diagnosis and Analysis of the Family Pedigree.
Author: Liu, Weidong|Zhang, Dongwei|Tan, Sanda A|Liu, Xiuli|Lai, Jinping
PMID: 30061258
Journal: Respir Med Case Rep. 2018 Jul 17;25:86-88.
Title: Isolated colonic metastasis two years after resection of stage IA primary adenocarcinoma of the lung: A case report.
Author: Vittorakis, Stylianos|Giannakopoulou, Georgia|Konstantinides, Konstantinos|Daskalaki, Anna|Samitas, Konstantinos
PMID: 30094153
Journal: Trans Am Clin Climatol Assoc. 2018;129:56-62.
Title: MOLECULAR FEATURES AND MOUSE MODELS OF COLORECTAL CANCER.
Author: Fearon, Eric R
PMID: 30166699
Journal: Am J Surg Pathol. 2018 Sep 12.
Title: SATB2 is Superior to CDX2 in Distinguishing Signet Ring Cell Carcinoma of the Upper Gastrointestinal Tract and Lower Gastrointestinal Tract.
Author: Ma, Changqing|Lowenthal, Brett M|Pai, Reetesh K
PMID: 30212392
Journal: Cancer Cell Int. 2018 Sep 10;18:137.
Title: Establishment and characterization of a cell line HCS1220 from human liver metastasis of colon cancer.
Author: Chai, Yi|Wang, Huan|Zhou, Fang
PMID: 30214379
Journal: Clin Epigenetics. 2018 Sep 26;10(1):120.
Title: CDX2 in colorectal cancer is an independent prognostic factor and regulated by promoter methylation and histone deacetylation in tumors of the serrated pathway.
Author: Graule, Janina|Uth, Kristin|Fischer, Elia|Centeno, Irene|Galvan, Jose A|Eichmann, Micha|Rau, Tilman T|Langer, Rupert|Dawson, Heather|Nitsche, Ulrich|Traeger, Peter|Berger, Martin D|Schnuriger, Beat|Hadrich, Marion|Studer, Peter|Inderbitzin, Daniel|Lugli,
PMID: 30257705
Journal: Asian J Surg. 2018 Sep 25. pii: S1015-9584(18)30287-2.
Title: The clincopathological variables to differentiate the nature of isolated pulmonary nodules in patients who received curative surgery for colorectal cancer.
Author: Chang, Tsung-Kun|Tsai, Hsiang-Lin|Su, Wei-Chih|Huang, Ching-Wen|Yeh, Yung-Sung|Ma, Cheng-Jen|Wang, Jaw-Yuan
PMID: 30262438
Journal: Clin Mol Hepatol. 2018 Oct 5. pii: cmh.2018.0067.
Title: Pathologic differential diagnosis of metastatic carcinoma in the liver.
Author: Park, Jeong Hwan|Kim, Jung Ho
PMID: 30300991
Journal: BMC Cancer. 2018 Oct 16;18(1):980.
Title: Impact of CDX2 expression status on the survival of patients after curative resection for colorectal cancer liver metastasis.
Author: Shigematsu, Yasuyuki|Inamura, Kentaro|Yamamoto, Noriko|Mise, Yoshihiro|Saiura, Akio|Ishikawa, Yuichi|Takahashi, Shunji|Kanda, Hiroaki
PMID: 30326864
Journal: J Med Case Rep. 2018 Oct 27;12(1):314.
Title: Recurrent biliary dissemination of colon cancer liver metastasis: a case report.
Author: Onishi, Ichiro|Kayahara, Masato|Takei, Ryohei|Makita, Naoki|Munemoto, Masayoshi|Yagi, Yasumichi|Kawashima, Atsuhiro
PMID: 30367665