Literatures

Primary Site >> Colorectal Cancer

Gene >> CDX1

1.
Journal:	Biochem Biophys Res Commun. 1997 Mar 27;232(3):742-8.
Title:	Human colorectal carcinogenesis is associated with deregulation of homeobox gene expression.
Author:	Vider, B Z\|Zimber, A\|Hirsch, D\|Estlein, D\|Chastre, E\|Prevot, S\|Gespach, C\|Yaniv, A\|Gazit, A
PMID:	9126347

2.
Journal:	Int J Cancer. 1997 Feb 20;74(1):35-44.
Title:	Molecular cloning, sequencing and expression of the mRNA encoding human Cdx1 and Cdx2 homeobox. Down-regulation of Cdx1 and Cdx2 mRNA expression during colorectal carcinogenesis.
Author:	Mallo, G V\|Rechreche, H\|Frigerio, J M\|Rocha, D\|Zweibaum, A\|Lacasa, M\|Jordan, B R\|Dusetti, N J\|Dagorn, J C\|Iovanna, J L
PMID:	9036867

3.
Journal:	J Biol Chem. 1998 May 29;273(22):14030-6.
Title:	Expression of the Cdx1 and Cdx2 homeotic genes leads to reduced malignancy in colon cancer-derived cells.
Author:	Mallo, G V\|Soubeyran, P\|Lissitzky, J C\|Andre, F\|Farnarier, C\|Marvaldi, J\|Dagorn, J C\|Iovanna, J L
PMID:	9593754

4.
Journal:	Mol Cell Biol Res Commun. 2000 May;3(5):271-6.
Title:	Overexpression of Cdx1 and Cdx2 homeogenes enhances expression of the HLA-I in HT-29 cells.
Author:	Soubeyran, P\|Mallo, G V\|Moucadel, V\|Dagorn, J C\|Iovanna, J L
PMID:	10964750

5.
Journal:	Biochim Biophys Acta. 2001 Sep 28;1537(2):89-100.
Title:	CDX-1 and CDX-2 are expressed in human colonic mucosa and are down-regulated in patients with Hirschsprung's disease associated enterocolitis.
Author:	Lui, V C\|Li, L\|Sham, M H\|Tam, P K
PMID:	11566252

6.
Journal:	Int J Oncol. 2002 Jan;20(1):23-9.
Title:	The caudal-related homeodomain protein CDX1 activates proliferating cell nuclear antigen expression in hepatocellular and colorectal carcinoma cells.
Author:	Oh, Eun-Jin\|Park, Jae-Hong\|Cho, Mong\|Lee, Won-Jae\|Choi, Yung Hyun\|Yoo, Mi-Ae
PMID:	11743638

7.
Journal:	FEBS Lett. 2002 May 8;518(1-3):83-7.
Title:	Stimulation of Cdx1 by oncogenic beta-catenin/Tcf4 in colon cancer cells; opposite effect of the CDX2 homeoprotein.
Author:	Domon-Dell, Claire\|Freund, Jean-Noel
PMID:	11997022

8.
Journal:	Gut. 2002 Aug;51(2):184-90.
Title:	Expression of CDX2 in normal and neoplastic human colon tissue and during differentiation of an in vitro model system.
Author:	Qualtrough, D\|Hinoi, T\|Fearon, E\|Paraskeva, C
PMID:	12117877

9.
Journal:	J Biol Chem. 2002 Sep 27;277(39):35795-800. Epub 2002 Jul 17.
Title:	DNA methylation down-regulates CDX1 gene expression in colorectal cancer cell lines.
Author:	Suh, Eun Ran\|Ha, Chong S\|Rankin, Erinn B\|Toyota, Minoru\|Traber, Peter G
PMID:	12124393

10.
Journal:	J Biol Chem. 2003 Sep 19;278(38):36611-20. Epub 2003 Jul 10.
Title:	Lewis type 1 antigen synthase (beta3Gal-T5) is transcriptionally regulated by homeoproteins.
Author:	Isshiki, Soichiro\|Kudo, Takashi\|Nishihara, Shoko\|Ikehara, Yuzuru\|Togayachi, Akira\|Furuya, Akiko\|Shitara, Kenya\|Kubota, Tetsuro\|Watanabe, Masahiko\|Kitajima, Masaki\|Narimatsu, Hisashi
PMID:	12855703

11.
Journal:	Oncogene. 2003 Sep 11;22(39):7913-21.
Title:	Cdx1 homeobox gene during human colon cancer progression.
Author:	Domon-Dell, Claire\|Schneider, Anne\|Moucadel, Virginie\|Guerin, Eric\|Guenot, Dominique\|Aguillon, Sarah\|Duluc, Isabelle\|Martin, Elisabeth\|Iovanna, Juan\|Launay, Jean-Francois\|Duclos, Bernard\|Chenard, Marie-Pierre\|Meyer, Christian\|Oudet, Pierre\|Kedinger, Miche
PMID:	12970739

12.
Journal:	Oncogene. 2003 Sep 25;22(41):6395-407.
Title:	Cdx1 inhibits the proliferation of human colon cancer cells by reducing cyclin D1 gene expression.
Author:	Lynch, John\|Keller, Matthew\|Guo, Rong-Jun\|Yang, Donald\|Traber, Peter
PMID:	14508520

13.
Journal:	Proc Natl Acad Sci U S A. 2004 Jan 13;101(2):574-9. Epub 2004 Jan 2.
Title:	Loss of CDX1 expression in colorectal carcinoma: promoter methylation, mutation, and loss of heterozygosity analyses of 37 cell lines.
Author:	Wong, N A C S\|Britton, M P\|Choi, G S\|Stanton, T K\|Bicknell, D C\|Wilding, J L\|Bodmer, W F
PMID:	14704280

14.
Journal:	World J Gastroenterol. 2004 Dec 1;10(23):3441-54.
Title:	Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis.
Author:	Xu, Xiao-Li\|Yu, Jian\|Zhang, Hong-Yu\|Sun, Meng-Hong\|Gu, Jun\|Du, Xiang\|Shi, Da-Ren\|Wang, Peng\|Yang, Zhen-Hua\|Zhu, Jing-De
PMID:	15526363

15.
Journal:	J Pathol. 2004 Nov;204(3):289-95.
Title:	CDX1 expression is reduced in colorectal carcinoma and is associated with promoter hypermethylation.
Author:	Pilozzi, Emanuela\|Onelli, Mariadele Rapazzotti\|Ziparo, Vincenzo\|Mercantini, Paolo\|Ruco, Luigi
PMID:	15378566

16.
Journal:	J Biol Chem. 2004 Aug 27;279(35):36865-75. Epub 2004 Jun 23.
Title:	Cdx1 inhibits human colon cancer cell proliferation by reducing beta-catenin/T-cell factor transcriptional activity.
Author:	Guo, Rong-Jun\|Huang, Edward\|Ezaki, Toshihiko\|Patel, Neesha\|Sinclair, Kristen\|Wu, Jinling\|Klein, Peter\|Suh, Eun-Ran\|Lynch, John P
PMID:	15215241

17.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2005 Aug;289(2):G285-90. Epub 2005 Mar
Title:	Differential regulation of intestinal alkaline phosphatase gene expression by Cdx1 and Cdx2.
Author:	Alkhoury, Fuad\|Malo, Madhu S\|Mozumder, Moushumi\|Mostafa, Golam\|Hodin, Richard A
PMID:	15774940

18.
Journal:	Korean J Intern Med. 2005 Dec;20(4):317-24.
Title:	Relationships between the expressions of CDX1 and CDX2 mRNA and clinicopathologic features in colorectal cancers.
Author:	Kim, Gwang Ha\|Lee, Dong Hyun\|Kim, Hyung Wook\|Cheong, Jong Yun\|Seo, Soo Boon\|Heo, Jeong\|Kang, Dae Hwan\|Song, Geun Am\|Cho, Mong\|Yang, Ung Suk\|Park, Do Youn\|Yoo, Mi Ae
PMID:	16491830

19.
Journal:	Clin Chem. 2006 Mar;52(3):520-3.
Title:	Identification of mRNA markers for molecular staging of lymph nodes in colorectal cancer.
Author:	Xi, Liqiang\|Gooding, William\|McCarty, Kenneth\|Godfrey, Tony E\|Hughes, Steven J
PMID:	16510433

20.
Journal:	J Hum Genet. 2006;51(5):391-6. Epub 2006 Apr 5.
Title:	Cancer genetics: colorectal cancer as a model.
Author:	Bodmer, Walter F
PMID:	16596323

21.
Journal:	Eur J Cancer. 2007 Mar;43(5):947-54.
Title:	Cytostatic drug treatment causes seeding of gene promoter methylation.
Author:	Bredberg, Anders\|Bodmer, Walter
PMID:	17236756

22.
Journal:	Mol Cancer Res. 2008 Sep;6(9):1478-90.
Title:	Repression of the desmocollin 2 gene expression in human colon cancer cells is relieved by the homeodomain transcription factors Cdx1 and Cdx2.
Author:	Funakoshi, Shinsuke\|Ezaki, Toshihiko\|Kong, Jianping\|Guo, Rong Jun\|Lynch, John P
PMID:	18819935

23.
Journal:	Oncogene. 2008 Jul 24;27(32):4497-502.
Title:	Cdx1, a dispensable homeobox gene for gut development with limited effect in intestinal cancer.
Author:	Bonhomme, C\|Calon, A\|Martin, E\|Robine, S\|Neuville, A\|Kedinger, M\|Domon-Dell, C\|Duluc, I\|Freund, J-N
PMID:	18372917

24.
Journal:	Biochimie. 2008 May;90(5):697-704.
Title:	Differential regulation of CDX1 and CDX2 gene expression by deficiency in methyl group donors.
Author:	Lu, Xiaohong\|Freund, Jean-Noel\|Muller, Marc\|Ravey, Juliette\|Nicolas, Jean-Pierre\|Gueant, Jean-Louis\|Namour, Fares
PMID:	18187048

25.
Journal:	Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1936-41.
Title:	Gastrointestinal differentiation marker Cytokeratin 20 is regulated by homeobox gene CDX1.
Author:	Chan, Carol W M\|Wong, Newton A\|Liu, Ying\|Bicknell, David\|Turley, Helen\|Hollins, Laura\|Miller, Crispin J\|Wilding, Jennifer L\|Bodmer, Walter F
PMID:	19188603

26.
Journal:	Mol Cancer. 2009 Sep 25;8:77.
Title:	Selective activation of tumor growth-promoting Ca2+ channel MS4A12 in colon cancer by caudal type homeobox transcription factor CDX2.
Author:	Koslowski, Michael\|Tureci, Ozlem\|Huber, Christoph\|Sahin, Ugur
PMID:	19781065

27.
Journal:	Gastroenterology. 2010 Feb;138(2):627-35.
Title:	CDX transcription factors positively regulate expression of solute carrier family 5, member 8 in the colonic epithelium.
Author:	Kakizaki, Fumihiko\|Aoki, Koji\|Miyoshi, Hiroyuki\|Carrasco, Nancy\|Aoki, Masahiro\|Taketo, Makoto M
PMID:	19900445

28.
Journal:	Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3722-7.
Title:	Cancer stem cells from colorectal cancer-derived cell lines.
Author:	Yeung, Trevor M\|Gandhi, Shaan C\|Wilding, Jennifer L\|Muschel, Ruth\|Bodmer, Walter F
PMID:	20133591

29.
Journal:	Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4382-7.
Title:	Hypoxia and lineage specification of cell line-derived colorectal cancer stem cells.
Author:	Yeung, Trevor M\|Gandhi, Shaan C\|Bodmer, Walter F
PMID:	21368208

30.
Journal:	Epigenetics. 2011 May;6(5):610-22. Epub 2011 May 1.
Title:	Class I and III HDACs and loss of active chromatin features contribute to epigenetic silencing of CDX1 and EPHB tumor suppressor genes in colorectal cancer.
Author:	Ronsch, Kerstin\|Jager, Marcel\|Schopflin, Anja\|Danciu, Mihai\|Lassmann, Silke\|Hecht, Andreas
PMID:	21393996

31.
Journal:	PLoS One. 2012;7(6):e37174.
Title:	Caudal homeobox protein Cdx-2 cooperates with Wnt pathway to regulate claudin-1 expression in colon cancer cells.
Author:	Bhat, Ajaz A\|Sharma, Ashok\|Pope, Jillian\|Krishnan, Moorthy\|Washington, Mary K\|Singh, Amar B\|Dhawan, Punita
PMID:	22719836

32.
Journal:	Cancer Res. 2013 Sep 15;73(18):5798-809.
Title:	Stem cell differentiation and lumen formation in colorectal cancer cell lines and primary tumors.
Author:	Ashley, Neil\|Yeung, Trevor M\|Bodmer, Walter F
PMID:	23867471

33.
Journal:	Biochem Biophys Res Commun. 2013 May 17;434(4):898-903.
Title:	Autophagy of cancer stem cells is involved with chemoresistance of colon cancer cells.
Author:	Wu, Shaobin\|Wang, Xianwei\|Chen, Jinxiang\|Chen, Yuxiang
PMID:	23624503

34.
Journal:	Gene. 2013 Jul 25;524(2):214-9.
Title:	Oxidative stress causes epigenetic alteration of CDX1 expression in colorectal cancer cells.
Author:	Zhang, Rui\|Kang, Kyoung Ah\|Kim, Ki Cheon\|Na, Soo-Young\|Chang, Weon Young\|Kim, Gi Young\|Kim, Hye Sun\|Hyun, Jin Won
PMID:	23618814

35.
Journal:	FASEB J. 2014 Feb;28(2):946-55.
Title:	Transcriptional control of the B3GALT5 gene by a retroviral promoter and methylation of distant regulatory elements.
Author:	Zulueta, Aida\|Caretti, Anna\|Signorelli, Paola\|Dall'olio, Fabio\|Trinchera, Marco
PMID:	24128890

36.
Journal:	J Biol Chem. 2014 Nov 28;289(48):33343-54.
Title:	Cdx1 and Cdx2 function as tumor suppressors.
Author:	Hryniuk, Alexa\|Grainger, Stephanie\|Savory, Joanne G A\|Lohnes, David
PMID:	25320087

37.
Journal:	PLoS One. 2014 Nov 25;9(11):e113071.
Title:	Predictive gene signatures: molecular markers distinguishing colon adenomatous polyp and carcinoma.
Author:	Drew, Janice E\|Farquharson, Andrew J\|Mayer, Claus Dieter\|Vase, Hollie F\|Coates, Philip J\|Steele, Robert J\|Carey, Francis A
PMID:	25423035

38.
Journal:	Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1550-8.
Title:	The CDX1-microRNA-215 axis regulates colorectal cancer stem cell differentiation.
Author:	Jones, Matthew F\|Hara, Toshifumi\|Francis, Princy\|Li, Xiao Ling\|Bilke, Sven\|Zhu, Yuelin\|Pineda, Marbin\|Subramanian, Murugan\|Bodmer, Walter F\|Lal, Ashish
PMID:	25775580

39.
Journal:	Carcinogenesis. 2015 Jul;36(7):719-29.
Title:	Reducing DNA methylation suppresses colon carcinogenesis by inducing tumor cell differentiation.
Author:	Hatano, Yuichiro\|Semi, Katsunori\|Hashimoto, Kyoichi\|Lee, Myeong Sup\|Hirata, Akihiro\|Tomita, Hiroyuki\|Kuno, Toshiya\|Takamatsu, Manabu\|Aoki, Koji\|Taketo, Makoto M\|Kim, Young-Joon\|Hara, Akira\|Yamada, Yasuhiro
PMID:	25939752

40.
Journal:	Mol Cell Proteomics. 2016 Jan;15(1):124-40.
Title:	N-glycosylation Profiling of Colorectal Cancer Cell Lines Reveals Association of Fucosylation with Differentiation and Caudal Type Homebox 1 (CDX1)/Villin mRNA Expression.
Author:	Holst, Stephanie\|Deuss, Anna J M\|van Pelt, Gabi W\|van Vliet, Sandra J\|Garcia-Vallejo, Juan J\|Koeleman, Carolien A M\|Deelder, Andre M\|Mesker, Wilma E\|Tollenaar, Rob A\|Rombouts, Yoann\|Wuhrer, Manfred
PMID:	26537799

41.
Journal:	Pathologe. 2016 Nov;37(Suppl 2):186-190.
Title:	[Pathogenetic aspects in precursor lesions of gastrointestinal tumors].
Author:	Rau, T
PMID:	27638535

42.
Journal:	World J Gastroenterol. 2016 Oct 7;22(37):8247-8256.
Title:	Impact of homeobox genes in gastrointestinal cancer.
Author:	Joo, Moon Kyung\|Park, Jong-Jae\|Chun, Hoon Jai
PMID:	27729732

43.
Journal:	J Pathol Clin Res. 2017 Jan 13;3(1):58-70.
Title:	Construction and analysis of tissue microarrays in the era of digital pathology: a pilot study targeting CDX1 and CDX2 in a colon cancer cohort of 612 patients.
Author:	Nolte, Sarah\|Zlobec, Inti\|Lugli, Alessandro\|Hohenberger, Werner\|Croner, Roland\|Merkel, Susanne\|Hartmann, Arndt\|Geppert, Carol I\|Rau, Tilman T
PMID:	28138402

44.
Journal:	Histopathology. 2017 Jul;71(1):34-41.
Title:	A33 shows similar sensitivity to but is more specific than CDX2 as an immunomarker of colorectal carcinoma.
Author:	Wong, Newton A C S\|Adamczyk, Lukasz A\|Evans, Shanna\|Cullen, Jayne\|Oniscu, Anca\|Oien, Karin A
PMID:	28226180