Primary Site >> Liver Cancer
Gene >> CDKN2B
| 1. | |||||||||||
| Journal: | J Gastroenterol. 1997 Feb;32(1):40-6. | ||||||||||
| Title: | Alterations in the tumor suppressor genes p53, RB, p16/MTS1, and p15/MTS2 in human pancreatic cancer and hepatoma cell lines. | ||||||||||
| Author: | Kaino, M | ||||||||||
| PMID: | 9058294 | ||||||||||
| 2. | |||||||||||
| Journal: | Hepatology. 1998 Apr;27(4):989-95. | ||||||||||
| Title: | Analysis of CDKN2A, CDKN2B, CDKN2C, and cyclin Ds gene status in hepatoblastoma. | ||||||||||
| Author: | Iolascon, A|Giordani, L|Moretti, A|Basso, G|Borriello, A|Della Ragione, F | ||||||||||
| PMID: | 9537438 | ||||||||||
| 3. | |||||||||||
| Journal: | Eur J Cancer. 1998 Oct;34(11):1789-95. | ||||||||||
| Title: | Infrequent mutations and no methylation of CDKN2A (P16/MTS1) and CDKN2B (p15/MTS2) in hepatocellular carcinoma in Taiwan. | ||||||||||
| Author: | Lin, Y W|Chen, C H|Huang, G T|Lee, P H|Wang, J T|Chen, D S|Lu, F J|Sheu, J C | ||||||||||
| PMID: | 9893670 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Res. 2000 Mar 1;60(5):1394-402. | ||||||||||
| Title: | Autocrine stimulatory mechanism by transforming growth factor beta in human hepatocellular carcinoma. | ||||||||||
| Author: | Matsuzaki, K|Date, M|Furukawa, F|Tahashi, Y|Matsushita, M|Sakitani, K|Yamashiki, N|Seki, T|Saito, H|Nishizawa, M|Fujisawa, J|Inoue, K | ||||||||||
| PMID: | 10728705 | ||||||||||
| 5. | |||||||||||
| Journal: | Chin Med J (Engl). 2000 Sep;113(9):817-22. | ||||||||||
| Title: | Deletion of chromosomes 9p and 17 associated with abnormal expression of p53, p16/MTS1 and p15/MTS2 gene protein in hepatocellular carcinomas. | ||||||||||
| Author: | Shao, J|Li, Y|Li, H|Wu, Q|Hou, J|Liew, C | ||||||||||
| PMID: | 11776078 | ||||||||||
| 6. | |||||||||||
| Journal: | Oncogene. 2002 Feb 28;21(10):1518-26. | ||||||||||
| Title: | Recurrent allelic deletions at mouse chromosomes 4 and 14 in Myc-induced liver tumors. | ||||||||||
| Author: | Wu, Yuanfei|Renard, Claire-Angelique|Apiou, Francoise|Huerre, Michel|Tiollais, Pierre|Dutrillaux, Bernard|Buendia, Marie Annick | ||||||||||
| PMID: | 11896580 | ||||||||||
| 7. | |||||||||||
| Journal: | Mol Cells. 2002 Jun 30;13(3):481-7. | ||||||||||
| Title: | Quantification of tumor suppressor mRNA expression by poly-competitive RT-PCR using a TS-IS that contained multiple internal competitors. | ||||||||||
| Author: | Jung, Hee-Jung|Chae, Ji Hyung|Kim, Hoguen|Park, Jeon Han|Lee, Jong Soo|Choi, Woong Hwan|Kim, Chul Geun | ||||||||||
| PMID: | 12132590 | ||||||||||
| 8. | |||||||||||
| Journal: | BMC Cancer. 2002 Nov 15;2:29. Epub 2002 Nov 15. | ||||||||||
| Title: | Methylation profiling of twenty promoter-CpG islands of genes which may contribute to hepatocellular carcinogenesis. | ||||||||||
| Author: | Yu, Jian|Ni, Min|Xu, Jian|Zhang, Hongyu|Gao, Baomei|Gu, Jianren|Chen, Jianguo|Zhang, Lisheng|Wu, Mengchao|Zhen, Sushen|Zhu, Jingde | ||||||||||
| PMID: | 12433278 | ||||||||||
| 9. | |||||||||||
| Journal: | Cancer Genet Cytogenet. 2003 Oct 1;146(1):8-15. | ||||||||||
| Title: | Clinicopathologic significance of genetic alterations in hepatocellular carcinoma. | ||||||||||
| Author: | Pang, A|Ng, I O|Fan, S T|Kwong, Y L | ||||||||||
| PMID: | 14499690 | ||||||||||
| 10. | |||||||||||
| Journal: | Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2004 Apr;21(2):132-7. | ||||||||||
| Title: | [Impact of p16INK4A and p15INK4B on human hepatocellular carcinoma cell proliferation and apoptosis]. | ||||||||||
| Author: | Qin, Yang|Liu, Jian-yu|Li, Bo|Peng, Wen-zhen|Fu, Ming-de|Sun, Zhi-lin|Sun, Ze-fang | ||||||||||
| PMID: | 15079795 | ||||||||||
| 11. | |||||||||||
| Journal: | Liver Int. 2005 Dec;25(6):1209-16. | ||||||||||
| Title: | Methylation status of p14ARF, p15INK4b, and p16INK4a genes in human hepatocellular carcinoma. | ||||||||||
| Author: | Fukai, Kenichi|Yokosuka, Osamu|Imazeki, Fumio|Tada, Motohisa|Mikata, Rintaro|Miyazaki, Masaru|Ochiai, Takenori|Saisho, Hiromitsu | ||||||||||
| PMID: | 16343074 | ||||||||||
| 12. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2007 Aug 7;104(32):13028-33. | ||||||||||
| Title: | Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation. | ||||||||||
| Author: | Wu, Chi-Hwa|van Riggelen, Jan|Yetil, Alper|Fan, Alice C|Bachireddy, Pavan|Felsher, Dean W | ||||||||||
| PMID: | 17664422 | ||||||||||
| 13. | |||||||||||
| Journal: | Mod Pathol. 2008 Jun;21(6):670-5. | ||||||||||
| Title: | Epigenetic instability is rare in fibrolamellar carcinomas but common in viral-associated hepatocellular carcinomas. | ||||||||||
| Author: | Vivekanandan, Perumal|Torbenson, Michael | ||||||||||
| PMID: | 18264082 | ||||||||||
| 14. | |||||||||||
| Journal: | Cancer Genet Cytogenet. 2009 Dec;195(2):112-9. | ||||||||||
| Title: | Methylation profiling of tumor suppressor genes and oncogenes in hepatitis virus-related hepatocellular carcinoma in northern India. | ||||||||||
| Author: | Kiran, Manjula|Chawla, Yogesh K|Kaur, Jyotdeep | ||||||||||
| PMID: | 19963110 | ||||||||||
| 15. | |||||||||||
| Journal: | Ann Surg Oncol. 2010 Jul;17(7):1917-26. | ||||||||||
| Title: | CpG island methylator phenotype associated with tumor recurrence in tumor-node-metastasis stage I hepatocellular carcinoma. | ||||||||||
| Author: | Li, Binkui|Liu, Wenji|Wang, Li|Li, Meixiang|Wang, Jianping|Huang, Liang|Huang, Pinzhu|Yuan, Yunfei | ||||||||||
| PMID: | 20112070 | ||||||||||
| 16. | |||||||||||
| Journal: | Hepatology. 2010 Nov;52(5):1808-18. | ||||||||||
| Title: | The transcription factors signal transducer and activator of transcription 5A (STAT5A) and STAT5B negatively regulate cell proliferation through the activation of cyclin-dependent kinase inhibitor 2b (Cdkn2b) and Cdkn1a expression. | ||||||||||
| Author: | Yu, Ji Hoon|Zhu, Bing-Mei|Wickre, Mark|Riedlinger, Gregory|Chen, Weiping|Hosui, Atsushi|Robinson, Gertraud W|Hennighausen, Lothar | ||||||||||
| PMID: | 21038417 | ||||||||||
| 17. | |||||||||||
| Journal: | Toxicology. 2011 Apr 28;283(1):8-17. | ||||||||||
| Title: | Concomitant apoptosis and regeneration of liver cells as a mechanism of liver-tumor promotion by beta-naphthoflavone involving TNFalpha-signaling due to oxidative cellular stress in rats. | ||||||||||
| Author: | Kuwata, Kazunori|Shibutani, Makoto|Hayashi, Hitomi|Shimamoto, Keisuke|Hayashi, Shim-Mo|Suzuki, Kazuhiko|Mitsumori, Kunitoshi | ||||||||||
| PMID: | 21295105 | ||||||||||
| 18. | |||||||||||
| Journal: | Int J Cancer. 2012 Apr 15;130(8):1745-54. | ||||||||||
| Title: | Aryl hydrocarbon receptor nuclear translocator is associated with tumor growth and progression of hepatocellular carcinoma. | ||||||||||
| Author: | Liang, Ying|Li, Wei-Wei|Yang, Bi-Wei|Tao, Zhong-Hua|Sun, Hui-Chuan|Wang, Lu|Xia, Jing-Lin|Qin, Lun-Xiu|Tang, Zhao-You|Fan, Jia|Wu, Wei-Zhong | ||||||||||
| PMID: | 21544813 | ||||||||||
| 19. | |||||||||||
| Journal: | Liver Int. 2012 Mar;32(3):420-8. | ||||||||||
| Title: | Quantitative methylation analysis reveals gender and age differences in p16INK4a hypermethylation in hepatitis B virus-related hepatocellular carcinoma. | ||||||||||
| Author: | Wang, Yongfeng|Cheng, Jin|Xu, Chunhui|Liu, Shuang|Jiang, Suzhen|Xu, Qiang|Chen, Xiangmei|Zhuang, Hui|Lu, Fengmin | ||||||||||
| PMID: | 22192146 | ||||||||||
| 20. | |||||||||||
| Journal: | Hepatology. 2013 Aug;58(2):706-17. | ||||||||||
| Title: | Genomic landscape of copy number aberrations enables the identification of oncogenic drivers in hepatocellular carcinoma. | ||||||||||
| Author: | Wang, Kai|Lim, Ho Yeong|Shi, Stephanie|Lee, Jeeyun|Deng, Shibing|Xie, Tao|Zhu, Zhou|Wang, Yuli|Pocalyko, David|Yang, Wei Jennifer|Rejto, Paul A|Mao, Mao|Park, Cheol-Keun|Xu, Jiangchun | ||||||||||
| PMID: | 23505090 | ||||||||||
| 21. | |||||||||||
| Journal: | Toxicol In Vitro. 2013 Sep;27(6):1809-19. | ||||||||||
| Title: | Cylindrospermopsin induced transcriptional responses in human hepatoma HepG2 cells. | ||||||||||
| Author: | Straser, Alja|Filipic, Metka|Zegura, Bojana | ||||||||||
| PMID: | 23726867 | ||||||||||
| 22. | |||||||||||
| Journal: | Oncol Rep. 2014 Mar;31(3):1364-72. | ||||||||||
| Title: | Latexin exhibits tumor suppressor potential in hepatocellular carcinoma. | ||||||||||
| Author: | Ni, Qing-Feng|Tian, Yuan|Kong, Liang-Liang|Lu, Ye-Ting|Ding, Wen-Zhou|Kong, Lian-Bao | ||||||||||
| PMID: | 24399246 | ||||||||||
| 23. | |||||||||||
| Journal: | Hepatology. 2014 Nov;60(5):1686-96. | ||||||||||
| Title: | Exome sequencing of hepatoblastoma reveals novel mutations and cancer genes in the Wnt pathway and ubiquitin ligase complex. | ||||||||||
| Author: | Jia, Deshui|Dong, Rui|Jing, Ying|Xu, Dan|Wang, Qifeng|Chen, Lei|Li, Qigen|Huang, Yuping|Zhang, Yuannv|Zhang, Zhenfeng|Liu, Li|Zheng, Shan|Xia, Qiang|Wang, Hongyang|Dong, Kuiran|He, Xianghuo | ||||||||||
| PMID: | 24912477 | ||||||||||
| 24. | |||||||||||
| Journal: | Hepatology. 2014 Nov;60(5):1620-36. | ||||||||||
| Title: | Reduced expression of transcriptional intermediary factor 1 gamma promotes metastasis and indicates poor prognosis of hepatocellular carcinoma. | ||||||||||
| Author: | Ding, Ze-yang|Jin, Guan-nan|Wang, Wei|Chen, Wei-xun|Wu, Yan-hui|Ai, Xi|Chen, Lin|Zhang, Wan-guang|Liang, Hui-fang|Laurence, Arian|Zhang, Ming-zhi|Datta, Pran K|Zhang, Bixiang|Chen, Xiao-ping | ||||||||||
| PMID: | 24954480 | ||||||||||
| 25. | |||||||||||
| Journal: | Oncol Lett. 2014 Sep;8(3):963-968. | ||||||||||
| Title: | Aberrant DNA methylation in hepatocellular carcinoma tumor suppression (Review). | ||||||||||
| Author: | Dong, Youhong|Wang, Anping | ||||||||||
| PMID: | 25120642 | ||||||||||
| 26. | |||||||||||
| Journal: | Oncol Rep. 2015 Mar;33(3):1191-200. | ||||||||||
| Title: | (+)Terrein inhibits human hepatoma Bel7402 proliferation through cell cycle arrest. | ||||||||||
| Author: | Zhang, Fengli|Mijiti, Meiheriguli|Ding, Wei|Song, Jiale|Yin, Ying|Sun, Wei|Li, Zhiyong | ||||||||||
| PMID: | 25592371 | ||||||||||
| 27. | |||||||||||
| Journal: | J Hematol Oncol. 2015 May 29;8(1):57. | ||||||||||
| Title: | Long non-coding RNA ANRIL is upregulated in hepatocellular carcinoma and regulates cell proliferation by epigenetic silencing of KLF2. | ||||||||||
| Author: | Huang, Ming-de|Chen, Wen-Ming|Qi, Fu-Zhen|Xia, Rui|Sun, Ming|Xu, Tong-Peng|Yin, Li|Zhang, Er-Bao|De, Wei|Shu, Yong-Qian | ||||||||||
| PMID: | 27391317 | ||||||||||
| 28. | |||||||||||
| Journal: | Mol Med Rep. 2016 Jan;13(1):243-8. | ||||||||||
| Title: | Mitogen-activated protein kinase kinase 3 induces cell cycle arrest via p38 activation mediated Bmi-1 downregulation in hepatocellular carcinoma. | ||||||||||
| Author: | Wang, Lin|Chen, Chen|Feng, Shuzhi|Lei, Ping|Tian, Jianli | ||||||||||
| PMID: | 26573508 | ||||||||||
| 29. | |||||||||||
| Journal: | Oncotarget. 2017 Aug 18;8(48):84153-84167. | ||||||||||
| Title: | Long non-coding RNA SNHG15 inhibits P15 and KLF2 expression to promote pancreatic cancer proliferation through EZH2-mediated H3K27me3. | ||||||||||
| Author: | Ma, Zhonghua|Huang, Hesuyuan|Wang, Jirong|Zhou, Yan|Pu, Fuxing|Zhao, Qinghong|Peng, Peng|Hui, Bingqing|Ji, Hao|Wang, Keming | ||||||||||
| PMID: | 29137412 | ||||||||||
| 30. | |||||||||||
| Journal: | Oncotarget. 2017 Oct 26;8(66):110052-110063. | ||||||||||
| Title: | CDKN2B is critical for verapamil-mediated reversal of doxorubicin resistance in hepatocellular carcinoma. | ||||||||||
| Author: | Zhang, Tengyue|Ma, Kelong|Huang, Jin|Wang, Shitang|Liu, Yabei|Fan, Gaofei|Liu, Miao|Yang, Guangshan|Wang, Cheng|Fan, Pingsheng | ||||||||||
| PMID: | 29299129 | ||||||||||
| 31. | |||||||||||
| Journal: | Cell Death Discov. 2018 Mar 12;4:42. | ||||||||||
| Title: | Regulation of transforming growth factor is involved in the efficacy of combined 5-fluorouracil and interferon alpha-2b therapy of advanced hepatocellular carcinoma. | ||||||||||
| Author: | Okada, Youhei|Wang, Ting|Kasai, Kazuhiro|Suzuki, Kazuyuki|Takikawa, Yasuhiro | ||||||||||
| PMID: | 29560281 | ||||||||||
| 32. | |||||||||||
| Journal: | J Viral Hepat. 2018 Jul 3. | ||||||||||
| Title: | UBE2L3, a susceptibility gene that plays oncogenic role in hepatitis B-related hepatocellular carcinoma. | ||||||||||
| Author: | Liu, Yao|Song, Ci|Ni, Hengli|Jiao, Weijuan|Gan, Wenjuan|Dong, Xiaoqiang|Liu, Jibin|Zhu, Liguo|Zhai, Xiangjun|Hu, Zhibin|Li, Jianming | ||||||||||
| PMID: | 29969176 | ||||||||||
| 33. | |||||||||||
| Journal: | PeerJ. 2018 Jul 18;6:e5203. | ||||||||||
| Title: | Microarray gene expression profiling in colorectal (HCT116) and hepatocellular (HepG2) carcinoma cell lines treated with Melicope ptelefolia leaf extract reveals transcriptome profiles exhibiting anticancer activity. | ||||||||||
| Author: | Kabir, Mohammad Faujul|Mohd Ali, Johari|Haji Hashim, Onn | ||||||||||
| PMID: | 30042885 | ||||||||||