Primary Site >> Liver Cancer
Gene >> CDKN2B
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Ref: Alterations in the tumor suppressor genes p53, RB, p16/MTS1, and p15/MTS2 in human pancreatic cancer and hepatoma cell lines. PMID: 9058294 |
Ref: Analysis of CDKN2A, CDKN2B, CDKN2C, and cyclin Ds gene status in hepatoblastoma. PMID: 9537438 Ref: Infrequent mutations and no methylation of CDKN2A (P16/MTS1) and CDKN2B (p15/MTS2) in hepatocellular carcinoma in Taiwan. PMID: 9893670 |
Ref: Autocrine stimulatory mechanism by transforming growth factor beta in human hepatocellular carcinoma. PMID: 10728705 Ref: Deletion of chromosomes 9p and 17 associated with abnormal expression of p53, p16/MTS1 and p15/MTS2 gene protein in hepatocellular carcinomas. PMID: 11776078 |
Ref: Recurrent allelic deletions at mouse chromosomes 4 and 14 in Myc-induced liver tumors. PMID: 11896580 Ref: Quantification of tumor suppressor mRNA expression by poly-competitive RT-PCR using a TS-IS that contained multiple internal competitors. PMID: 12132590 Ref: Methylation profiling of twenty promoter-CpG islands of genes which may contribute to hepatocellular carcinogenesis. PMID: 12433278 |
Ref: Clinicopathologic significance of genetic alterations in hepatocellular carcinoma. PMID: 14499690 |
Ref: [Impact of p16INK4A and p15INK4B on human hepatocellular carcinoma cell proliferation and apoptosis]. PMID: 15079795 |
Ref: Methylation status of p14ARF, p15INK4b, and p16INK4a genes in human hepatocellular carcinoma. PMID: 16343074 |
Ref: Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation. PMID: 17664422 |
Ref: Epigenetic instability is rare in fibrolamellar carcinomas but common in viral-associated hepatocellular carcinomas. PMID: 18264082 |
Ref: Methylation profiling of tumor suppressor genes and oncogenes in hepatitis virus-related hepatocellular carcinoma in northern India. PMID: 19963110 |
Ref: CpG island methylator phenotype associated with tumor recurrence in tumor-node-metastasis stage I hepatocellular carcinoma. PMID: 20112070 Ref: The transcription factors signal transducer and activator of transcription 5A (STAT5A) and STAT5B negatively regulate cell proliferation through the activation of cyclin-dependent kinase inhibitor 2b (Cdkn2b) and Cdkn1a expression. PMID: 21038417 |
Ref: Concomitant apoptosis and regeneration of liver cells as a mechanism of liver-tumor promotion by beta-naphthoflavone involving TNFalpha-signaling due to oxidative cellular stress in rats. PMID: 21295105 |
Ref: Aryl hydrocarbon receptor nuclear translocator is associated with tumor growth and progression of hepatocellular carcinoma. PMID: 21544813 Ref: Quantitative methylation analysis reveals gender and age differences in p16INK4a hypermethylation in hepatitis B virus-related hepatocellular carcinoma. PMID: 22192146 |
Ref: Genomic landscape of copy number aberrations enables the identification of oncogenic drivers in hepatocellular carcinoma. PMID: 23505090 Ref: Cylindrospermopsin induced transcriptional responses in human hepatoma HepG2 cells. PMID: 23726867 |
Ref: Latexin exhibits tumor suppressor potential in hepatocellular carcinoma. PMID: 24399246 Ref: Exome sequencing of hepatoblastoma reveals novel mutations and cancer genes in the Wnt pathway and ubiquitin ligase complex. PMID: 24912477 Ref: Reduced expression of transcriptional intermediary factor 1 gamma promotes metastasis and indicates poor prognosis of hepatocellular carcinoma. PMID: 24954480 Ref: Aberrant DNA methylation in hepatocellular carcinoma tumor suppression (Review). PMID: 25120642 |
Ref: (+)Terrein inhibits human hepatoma Bel7402 proliferation through cell cycle arrest. PMID: 25592371 Ref: Long non-coding RNA ANRIL is upregulated in hepatocellular carcinoma and regulates cell proliferation by epigenetic silencing of KLF2. PMID: 27391317 |
Ref: Mitogen-activated protein kinase kinase 3 induces cell cycle arrest via p38 activation mediated Bmi-1 downregulation in hepatocellular carcinoma. PMID: 26573508 |
Ref: Long non-coding RNA SNHG15 inhibits P15 and KLF2 expression to promote pancreatic cancer proliferation through EZH2-mediated H3K27me3. PMID: 29137412 Ref: CDKN2B is critical for verapamil-mediated reversal of doxorubicin resistance in hepatocellular carcinoma. PMID: 29299129 |
Ref: Regulation of transforming growth factor is involved in the efficacy of combined 5-fluorouracil and interferon alpha-2b therapy of advanced hepatocellular carcinoma. PMID: 29560281 Ref: UBE2L3, a susceptibility gene that plays oncogenic role in hepatitis B-related hepatocellular carcinoma. PMID: 29969176 Ref: Microarray gene expression profiling in colorectal (HCT116) and hepatocellular (HepG2) carcinoma cell lines treated with Melicope ptelefolia leaf extract reveals transcriptome profiles exhibiting anticancer activity. PMID: 30042885 |