Literatures

Primary Site >> Liver Cancer

Gene >> CDKN2A

1.
Journal:	J Cancer Res Clin Oncol. 1995;121(9-10):511-5.
Title:	Hepatocarcinogenesis in rodents and humans.
Author:	Kitagawa, T\|Miyasaka, K\|Kanda, H\|Yasui, H\|Hino, O
PMID:	7559729

2.
Journal:	Oncogene. 1995 Mar 2;10(5):827-33.
Title:	5'-Deoxy-5'-methylthioadenosine phosphorylase and p16INK4 deficiency in multiple tumor cell lines.
Author:	Della Ragione, F\|Russo, G\|Oliva, A\|Mastropietro, S\|Mancini, A\|Borrelli, A\|Casero, R A\|Iolascon, A\|Zappia, V
PMID:	7898924

3.
Journal:	Biol Pharm Bull. 1996 May;19(5):683-91.
Title:	Allelotype analysis in mouse hepatocellular carcinomas; frequent homozygous deletion of mouse homolog of p16/CDKN2 gene on chromosome 4 in culture.
Author:	Miyasaka, K\|Fukui, T\|Kitagawa, T
PMID:	8741575

4.
Journal:	Int J Cancer. 1996 Jul 17;67(2):176-80.
Title:	Infrequent alterations of the p16INK4A gene in liver cancer.
Author:	Kita, R\|Nishida, N\|Fukuda, Y\|Azechi, H\|Matsuoka, Y\|Komeda, T\|Sando, T\|Nakao, K\|Ishizaki, K
PMID:	8760583

5.
Journal:	Hepatology. 1996 Sep;24(3):575-9.
Title:	Inactivation of p16INK4 in hepatocellular carcinoma.
Author:	Hui, A M\|Sakamoto, M\|Kanai, Y\|Ino, Y\|Gotoh, M\|Yokota, J\|Hirohashi, S
PMID:	8781327

6.
Journal:	Biol Pharm Bull. 1996 Mar;19(3):345-9.
Title:	Homozygous deletion of mouse homolog of p16/CDKN2 gene on chromosome 4 in mouse liver epithelial cells in culture.
Author:	Miyasaka, K\|Kawauchi, S
PMID:	8924897

7.
Journal:	Oncol Rep. 1996 Mar;3(2):405-8.
Title:	Alterations of CDKN2(p16/MTS1) exon 2 in human hepatocellular carcinoma.
Author:	Qin, L\|Tang, Z\|Liu, K\|Ye, S\|He, B\|Zhang, Y\|Zhou, G
PMID:	21594383

8.
Journal:	Hepatology. 1997 Mar;25(3):593-7.
Title:	Frequency of mutation and deletion of the tumor suppressor gene CDKN2A (MTS1/p16) in hepatocellular carcinoma from an Australian population.
Author:	Biden, K\|Young, J\|Buttenshaw, R\|Searle, J\|Cooksley, G\|Xu, D B\|Leggett, B
PMID:	9049204

9.
Journal:	Cancer Res. 1997 Aug 1;57(15):3294-9.
Title:	Restriction landmark genomic scanning (RLGS-M)-based genome-wide scanning of mouse liver tumors for alterations in DNA methylation status.
Author:	Akama, T O\|Okazaki, Y\|Ito, M\|Okuizumi, H\|Konno, H\|Muramatsu, M\|Plass, C\|Held, W A\|Hayashizaki, Y
PMID:	9242463

10.
Journal:	Histol Histopathol. 1997 Oct;12(4):1019-25.
Title:	Alteration of cell cycle-related genes in hepatocarcinogenesis.
Author:	Nishida, N\|Fukuda, Y\|Ishizaki, K\|Nakao, K
PMID:	9302564

11.
Journal:	J Gastroenterol Hepatol. 1997 Oct;12(9-10):S309-13.
Title:	Molecular mechanism of hepatocarcinogenesis.
Author:	Sheu, J C
PMID:	9407351

12.
Journal:	Acta Med Okayama. 1997 Dec;51(6):313-9.
Title:	Comparison of cellular characteristics between human hepatoma cell lines with wild-type p53 and those with mutant-type p53 gene.
Author:	Pu, H\|Tsuji, T\|Kondo, A\|Fushimi, K\|Ohashi, R\|Inoue, Y\|Mimura, T\|Hamazaki, K\|Miyazaki, M\|Namba, M
PMID:	9439773

13.
Journal:	Cancer Lett. 1998 Jan 9;122(1-2):201-7.
Title:	Homozygous deletions of the CDKN2 gene and loss of heterozygosity of 9p in primary hepatocellular carcinoma.
Author:	Piao, Z\|Park, C\|Lee, J S\|Yang, C H\|Choi, K Y\|Kim, H
PMID:	9464511

14.
Journal:	Int J Oncol. 1998 Mar;12(3):583-8.
Title:	Mutational study of p16CDKN2/MTS1/INK4A and p57KIP2 genes in hepatocellular carcinoma.
Author:	Bonilla, F\|Orlow, I\|Cordon-Cardo, C
PMID:	9472096

15.
Journal:	Hepatology. 1998 Apr;27(4):989-95.
Title:	Analysis of CDKN2A, CDKN2B, CDKN2C, and cyclin Ds gene status in hepatoblastoma.
Author:	Iolascon, A\|Giordani, L\|Moretti, A\|Basso, G\|Borriello, A\|Della Ragione, F
PMID:	9537438

16.
Journal:	Carcinogenesis. 1998 Jun;19(6):1045-52.
Title:	Induction of mutations in Ki-ras and INK4a in liver tumors of mice exposed in utero to 3-methylcholanthrene.
Author:	Gressani, K M\|Rollins, L A\|Leone-Kabler, S\|Cline, J M\|Miller, M S
PMID:	9667743

17.
Journal:	Mutat Res. 1998 May 25;400(1-2):421-37.
Title:	Accumulation of genetic alterations and their significance in each primary human cancer and cell line.
Author:	Murakami, Y\|Sekiya, T
PMID:	9685701

18.
Journal:	Int J Oncol. 1998 Oct;13(4):669-76.
Title:	Alteration of the CDKN2A gene in pancreatic cancers: Is it a late event in the progression of pancreatic cancer?
Author:	Sugimoto, Y\|Morita, R\|Hikiji, K\|Imura, G\|Ogata, Y\|Yasuda, D\|Kono, A\|Iguchi, H
PMID:	9735394

19.
Journal:	Exp Mol Med. 1998 Jun 30;30(2):109-14.
Title:	Alterations of CDKN2 (MTS1/p16INK4A) gene in paraffin-embedded tumor tissues of human stomach, lung, cervix and liver cancers.
Author:	Kim, J R\|Kim, S Y\|Kim, M J\|Kim, J H
PMID:	9873831

20.
Journal:	Eur J Cancer. 1998 Oct;34(11):1789-95.
Title:	Infrequent mutations and no methylation of CDKN2A (P16/MTS1) and CDKN2B (p15/MTS2) in hepatocellular carcinoma in Taiwan.
Author:	Lin, Y W\|Chen, C H\|Huang, G T\|Lee, P H\|Wang, J T\|Chen, D S\|Lu, F J\|Sheu, J C
PMID:	9893670

21.
Journal:	Chin Med J (Engl). 1998 Apr;111(4):313-8.
Title:	Alterations of oncogenes, tumor suppressor genes and growth factors in hepatocellular carcinoma: with relation to tumor size and invasiveness.
Author:	Tang, Z\|Qin, L\|Wang, X\|Zhou, G\|Liao, Y\|Weng, Y\|Jiang, X\|Lin, Z\|Liu, K\|Ye, S
PMID:	10374394

22.
Journal:	Int J Cancer. 1999 May 5;81(3):319-24.
Title:	Frequent allelic loss on chromosome 9 in hepatocellular carcinoma.
Author:	Liew, C T\|Li, H M\|Lo, K W\|Leow, C K\|Lau, W Y\|Hin, L Y\|Lim, B K\|Lai, P B\|Chan, J Y\|Wang, X Q\|Wu, S\|Lee, J C
PMID:	10209942

23.
Journal:	Clin Cancer Res. 1999 Sep;5(9):2450-4.
Title:	Molecular detection of neoplastic cells in lymph nodes of metastatic colorectal cancer patients predicts recurrence.
Author:	Sanchez-Cespedes, M\|Esteller, M\|Hibi, K\|Cope, F O\|Westra, W H\|Piantadosi, S\|Herman, J G\|Jen, J\|Sidransky, D
PMID:	10499618

24.
Journal:	Zhonghua Gan Zang Bing Za Zhi. 1999 Sep;7(3):138-9.
Title:	[The correlation between integration of HBV X, S, Pre-S, C gene and the expression of oncogenes/tumor suppressor genes in primary hepatocellular carcinoma].
Author:	Zhang, L\|Cao, Y\|Song, J
PMID:	10572677

25.
Journal:	Oncology. 1999 Nov;57(4):306-10.
Title:	CDKN2 mutation is infrequent in german hepatocellular carcinoma.
Author:	Volkmann, M\|Stilgenbauer, F\|Hofmann, W J\|Otto, G\|Schiff, J H\|Fiehn, W
PMID:	10575317

26.
Journal:	World J Gastroenterol. 1999 Feb;5(1):25-27.
Title:	Effect of HCV infection on expression of several cancer-associated gene products in HCC.
Author:	Yang, Jian-Min\|Wang, Rong-Quan\|Bu, Bao-Guo\|Zhou, Zi-Cheng\|Fang, Dian-Chun\|Luo, Yuan-Hui
PMID:	11819378

27.
Journal:	Cancer Genet Cytogenet. 2000 Mar;117(2):118-24.
Title:	Alterations of P19ARF in rodent hepatoma cell lines but not in human primary liver cancer.
Author:	Laes, J\|Parada, L A\|Johansson, B\|Levan, G\|Szpirer, C\|Szpirer, J
PMID:	10704681

28.
Journal:	Genes Chromosomes Cancer. 2000 Apr;27(4):362-72.
Title:	A dual-color FISH framework map for the characterization of the Sai1 tumor suppression region on rat chromosome 5.
Author:	Helou, K\|Lu, X C\|Montelius-Alatalo, K\|Stahl, F\|Klinga-Levan, K\|Levan, G\|Rohme, D
PMID:	10719366

29.
Journal:	J Gastroenterol Hepatol. 2000 Feb;15(2):182-91.
Title:	Amino acid substitutions in codons 9-11 of hepatitis C virus core protein lead to the synthesis of a short core protein product.
Author:	Yeh, C T\|Lo, S Y\|Dai, D I\|Tang, J H\|Chu, C M\|Liaw, Y F
PMID:	10735543

30.
Journal:	Cancer. 2000 Jul 1;89(1):60-8.
Title:	p16 is a major inactivation target in hepatocellular carcinoma.
Author:	Jin, M\|Piao, Z\|Kim, N G\|Park, C\|Shin, E C\|Park, J H\|Jung, H J\|Kim, C G\|Kim, H
PMID:	10897001

31.
Journal:	Anticancer Res. 2000 May-Jun;20(3A):1621-6.
Title:	p16INK4 gene mutation and allelic loss of chromosome 9p21-22 in Taiwanese hepatocellular carcinoma.
Author:	Chen, T C\|Hsieh, L L\|Kuo, T T\|Ng, K F\|Wu Chou, Y H\|Jeng, L B\|Chen, M F
PMID:	10928081

32.
Journal:	Semin Cancer Biol. 2000 Jun;10(3):185-200.
Title:	Genetics of hepatocellular carcinoma.
Author:	Buendia, M A
PMID:	10936068

33.
Journal:	J Hepatol. 2000 Aug;33(2):254-65.
Title:	P53 but not p16INK4a induces growth arrest in retinoblastoma-deficient hepatocellular carcinoma cells.
Author:	Morel, A P\|Unsal, K\|Cagatay, T\|Ponchel, F\|Carr, B\|Ozturk, M
PMID:	10952243

34.
Journal:	Clin Cancer Res. 2000 Sep;6(9):3516-21.
Title:	Frequent p15 promoter methylation in tumor and peripheral blood from hepatocellular carcinoma patients.
Author:	Wong, I H\|Lo, Y M\|Yeo, W\|Lau, W Y\|Johnson, P J
PMID:	10999738

35.
Journal:	Hepatology. 2000 Nov;32(5):970-9.
Title:	Genetic instability and aberrant DNA methylation in chronic hepatitis and cirrhosis--A comprehensive study of loss of heterozygosity and microsatellite instability at 39 loci and DNA hypermethylation on 8 CpG islands in microdissected specimens from patie
Author:	Kondo, Y\|Kanai, Y\|Sakamoto, M\|Mizokami, M\|Ueda, R\|Hirohashi, S
PMID:	11050047

36.
Journal:	Cancer Lett. 2000 Nov 10;160(1):81-8.
Title:	5-Aza-2'-deoxycytidine leads to down-regulation of aberrant p16INK4A RNA transcripts and restores the functional retinoblastoma protein pathway in hepatocellular carcinoma cell lines.
Author:	Suh, S I\|Pyun, H Y\|Cho, J W\|Baek, W K\|Park, J B\|Kwon, T\|Park, J W\|Suh, M H\|Carson, D A
PMID:	11098088

37.
Journal:	Hepatogastroenterology. 2000 Nov-Dec;47(36):1663-8.
Title:	Abrogation of the p16-Rb pathway in Korean hepatocellular carcinomas.
Author:	Lee, T J\|Bae, J J\|Lee, J S\|Lee, S Y\|Kim, H J\|Kim, S K\|Lee, J Y\|Lee, T Y
PMID:	11149028

38.
Journal:	Cell Res. 2000 Dec;10(4):311-23.
Title:	Genetic aberration in primary hepatocellular carcinoma: correlation between p53 gene mutation and loss-of-heterozygosity on chromosome 16q21-q23 and 9p21-p23.
Author:	Wang, G\|Huang, C H\|Zhao, Y\|Cai, L\|Wang, Y\|Xiu, S J\|Jiang, Z W\|Yang, S\|Zhao, T\|Huang, W\|Gu, J R
PMID:	11191353

39.
Journal:	Chin Med J (Engl). 2000 Oct;113(10):889-93.
Title:	Molecular and immunohistochemical study of the inactivation of the p16 gene in primary hepatocellular carcinoma.
Author:	Huang, J\|Shen, W\|Li, B\|Luo, Y\|Liao, S\|Zhang, W\|Cheng, N
PMID:	11775834

40.
Journal:	Chin Med J (Engl). 2000 Sep;113(9):817-22.
Title:	Deletion of chromosomes 9p and 17 associated with abnormal expression of p53, p16/MTS1 and p15/MTS2 gene protein in hepatocellular carcinomas.
Author:	Shao, J\|Li, Y\|Li, H\|Wu, Q\|Hou, J\|Liew, C
PMID:	11776078

41.
Journal:	Hua Xi Yi Ke Da Xue Xue Bao. 2000 Sep;31(3):306-9.
Title:	[A study on the inactivation of p16 genes and the expression of P16 protein in primary hepatocellular carcinomas].
Author:	Huang, J\|Shen, W\|Li, B\|Luo, Y\|Liao, S\|Zhang, W\|Cheng, N
PMID:	12545816

42.
Journal:	Gut. 2001 Mar;48(3):372-7.
Title:	Detection of hypermethylation of the p16(INK4A) gene promoter in chronic hepatitis and cirrhosis associated with hepatitis B or C virus.
Author:	Kaneto, H\|Sasaki, S\|Yamamoto, H\|Itoh, F\|Toyota, M\|Suzuki, H\|Ozeki, I\|Iwata, N\|Ohmura, T\|Satoh, T\|Karino, Y\|Satoh, T\|Toyota, J\|Satoh, M\|Endo, T\|Omata, M\|Imai, K
PMID:	11171828

43.
Journal:	Hepatology. 2001 Mar;33(3):561-8.
Title:	Expression of mRNA for DNA methyltransferases and methyl-CpG-binding proteins and DNA methylation status on CpG islands and pericentromeric satellite regions during human hepatocarcinogenesis.
Author:	Saito, Y\|Kanai, Y\|Sakamoto, M\|Saito, H\|Ishii, H\|Hirohashi, S
PMID:	11230735

44.
Journal:	Br J Cancer. 2001 Apr 6;84(7):982-9.
Title:	Frequent k- ras -2 mutations and p16(INK4A)methylation in hepatocellular carcinomas in workers exposed to vinyl chloride.
Author:	Weihrauch, M\|Benicke, M\|Lehnert, G\|Wittekind, C\|Wrbitzky, R\|Tannapfel, A
PMID:	11286481

45.
Journal:	Mol Carcinog. 2001 Mar;30(3):138-50.
Title:	Sequential changes in hepatocarcinogenesis induced by diethylnitrosamine plus thioacetamide in Fischer 344 rats: induction of gankyrin expression in liver fibrosis, pRB degradation in cirrhosis, and methylation of p16(INK4A) exon 1 in hepatocellular carci
Author:	Park, T J\|Kim, H S\|Byun, K H\|Jang, J J\|Lee, Y S\|Lim, I K
PMID:	11301474

46.
Journal:	Oncology. 2001;60(4):346-54.
Title:	Disruption of the p16/cyclin D1/retinoblastoma protein pathway in the majority of human hepatocellular carcinomas.
Author:	Azechi, H\|Nishida, N\|Fukuda, Y\|Nishimura, T\|Minata, M\|Katsuma, H\|Kuno, M\|Ito, T\|Komeda, T\|Kita, R\|Takahashi, R\|Nakao, K
PMID:	11408803

47.
Journal:	Biochem Biophys Res Commun. 2001 Jul 13;285(2):183-7.
Title:	Involvement of p-15(INK4b) and p-16(INK4a) gene expression in saikosaponin a and TPA-induced growth inhibition of HepG2 cells.
Author:	Wu, W S\|Hsu, H Y
PMID:	11444823

48.
Journal:	J Korean Med Sci. 2001 Aug;16(4):424-32.
Title:	Expression of the G1-S modulators in hepatitis B virus-related hepatocellular carcinoma and dysplastic nodule: association of cyclin D1 and p53 proteins with the progression of hepatocellular carcinoma.
Author:	Choi, Y L\|Park, S H\|Jang, J J\|Park, C K
PMID:	11511787

49.
Journal:	Cancer Lett. 2001 Oct 22;172(1):59-66.
Title:	Alterations at the Ink4a locus in transplacentally induced murine lung tumors.
Author:	Mizesko, M C\|Grewe, C\|Grabner, A\|Miller, M S
PMID:	11595130

50.
Journal:	Zhonghua Gan Zang Bing Za Zhi. 2001 Oct;9(5):294-6.
Title:	[Correlation of c-myc gene amplification, MTS1/p16 gene alternation, and HBV infection in human hepatocellular carcinoma].
Author:	Zhang, J\|Wang, K\|Cong, S\|Qiu, F\|Wang, X\|Wang, P
PMID:	11676877

51.
Journal:	Chin Med J (Engl). 2001 Oct;114(10):1068-72.
Title:	Telomerase activity and homozygous deletions of the p16 gene in liver metastases of colorectal carcinoma.
Author:	Ma, J\|Zhan, W\|Peng, J\|He, Y\|Zheng, Z\|Cai, S\|Wang, L\|Wang, J
PMID:	11677769

52.
Journal:	Oncogene. 2001 Oct 25;20(48):7104-9.
Title:	INK4a-ARF alterations and p53 mutations in hepatocellular carcinomas.
Author:	Tannapfel, A\|Busse, C\|Weinans, L\|Benicke, M\|Katalinic, A\|Geissler, F\|Hauss, J\|Wittekind, C
PMID:	11704835

53.
Journal:	Cancer Cell Int. 2001 Dec 17;1(1):2.
Title:	Effect of 5-azacytidine and galectin-1 on growth and differentiation of the human b lymphoma cell line bl36.
Author:	Poirier, Florence\|Bourin, Philippe\|Bladier, Dominique\|Joubert-Caron, Raymonde\|Caron, Michel
PMID:	11983026

54.
Journal:	Hua Xi Yi Ke Da Xue Xue Bao. 2001 Dec;32(4):492-4, 500.
Title:	[Study of deletion and mutation of p16 gene in primary hepatocellular carcinoma].
Author:	Qin, Y\|Chen, J\|Li, B\|Sun, Z\|Zuo, F\|Sun, Z
PMID:	12528528

55.
Journal:	Hunan Yi Ke Da Xue Xue Bao. 2001 Dec 28;26(6):527-30.
Title:	[p16 and cyclinD1 protein expression and p16 gene mutation in primary human hepatocellular carcinoma].
Author:	Huang, G X\|Cheng, R X\|Feng, D Y
PMID:	12536530

56.
Journal:	Oncogene. 2002 Feb 28;21(10):1518-26.
Title:	Recurrent allelic deletions at mouse chromosomes 4 and 14 in Myc-induced liver tumors.
Author:	Wu, Yuanfei\|Renard, Claire-Angelique\|Apiou, Francoise\|Huerre, Michel\|Tiollais, Pierre\|Dutrillaux, Bernard\|Buendia, Marie Annick
PMID:	11896580

57.
Journal:	Br J Cancer. 2002 Apr 22;86(8):1290-6.
Title:	Cirrhotic livers reveal genetic changes in the MDM2-P14ARF system of cell cycle regulators.
Author:	Schlott, T\|Scharf, J G\|Gorzel, C\|Middel, P\|Spring, H
PMID:	11953887

58.
Journal:	J Gastroenterol Hepatol. 2002 Mar;17(3):301-7.
Title:	Reciprocal relationship between methylation status and loss of heterozygosity at the p14(ARF) locus in Australian and South African hepatocellular carcinomas.
Author:	Herath, Nirmitha I\|Kew, Michael C\|Walsh, Michael D\|Young, Joanne\|Powell, Lawrie W\|Leggett, Barbara A\|MacDonald, Graeme A
PMID:	11982701

59.
Journal:	J Natl Cancer Inst. 2002 May 15;94(10):755-61.
Title:	DNA methylation and environmental exposures in human hepatocellular carcinoma.
Author:	Shen, Lanlan\|Ahuja, Nita\|Shen, Yu\|Habib, Nagy A\|Toyota, Minoru\|Rashid, Asif\|Issa, Jean-Pierre J
PMID:	12011226

60.
Journal:	Cell Tissue Res. 2002 May;308(2):205-14. Epub 2002 Apr 11.
Title:	Establishment and characterization of four human pancreatic carcinoma cell lines. Genetic alterations in the TGFBR2 gene but not in the MADH4 gene.
Author:	Ku, Ja-Lok\|Yoon, Kyong-Ah\|Kim, Woo-Ho\|Jang, Young\|Suh, Kyung-Suk\|Kim, Sun-Whe\|Park, Yong-Hyun\|Park, Jae-Gahb
PMID:	12037578

61.
Journal:	Nihon Geka Gakkai Zasshi. 2002 Jun;103(6):472-5.
Title:	[Genetic detection and clinical applications in patients with hepatocellular carcinoma].
Author:	Takeda, Shin\|Nakao, Akimasa
PMID:	12094698

62.
Journal:	Cancer Res. 2002 Jul 15;62(14):3997-4006.
Title:	Growth inhibition of human hepatoma cells by acyclic retinoid is associated with induction of p21(CIP1) and inhibition of expression of cyclin D1.
Author:	Suzui, Masumi\|Masuda, Muneyuki\|Lim, Jin T E\|Albanese, Chris\|Pestell, Richard G\|Weinstein, I Bernard
PMID:	12124333

63.
Journal:	Mol Cells. 2002 Jun 30;13(3):481-7.
Title:	Quantification of tumor suppressor mRNA expression by poly-competitive RT-PCR using a TS-IS that contained multiple internal competitors.
Author:	Jung, Hee-Jung\|Chae, Ji Hyung\|Kim, Hoguen\|Park, Jeon Han\|Lee, Jong Soo\|Choi, Woong Hwan\|Kim, Chul Geun
PMID:	12132590

64.
Journal:	Zhonghua Yi Xue Za Zhi. 2002 May 10;82(9):601-5.
Title:	[Establishment of human hepatocellular carcinoma cell line with spontaneous pulmonary metastasis through in vivo selection].
Author:	Li, Yan\|Tang, Zhaoyou\|Ye, Shenglong\|Liu, Yinkun\|Chen, Jie\|Xue, Qiong\|Huang, Xiaowu\|Chen, Jun\|Bao, Weihua\|Yang, Jiong\|Gao, Dongmei
PMID:	12133480

65.
Journal:	Mol Carcinog. 2002 Oct;35(2):85-92.
Title:	High frequency of promoter hypermethylation of RASSF1A and p16 and its relationship to aflatoxin B1-DNA adduct levels in human hepatocellular carcinoma.
Author:	Zhang, Yu-Jing\|Ahsan, Habibul\|Chen, Yu\|Lunn, Ruth M\|Wang, Li-Yu\|Chen, Shu-Yuan\|Lee, Po-Huang\|Chen, Chien-Jen\|Santella, Regina M
PMID:	12325038

66.
Journal:	BMC Cancer. 2002 Nov 15;2:29. Epub 2002 Nov 15.
Title:	Methylation profiling of twenty promoter-CpG islands of genes which may contribute to hepatocellular carcinogenesis.
Author:	Yu, Jian\|Ni, Min\|Xu, Jian\|Zhang, Hongyu\|Gao, Baomei\|Gu, Jianren\|Chen, Jianguo\|Zhang, Lisheng\|Wu, Mengchao\|Zhen, Sushen\|Zhu, Jingde
PMID:	12433278

67.
Journal:	Mech Ageing Dev. 2002 Nov;123(12):1665-80.
Title:	Spectrum of molecular changes during hepatocarcinogenesis induced by DEN and other chemicals in Fischer 344 male rats.
Author:	Lim, In Kyoung
PMID:	12470904

68.
Journal:	Hepatobiliary Pancreat Dis Int. 2002 Feb;1(1):35-41.
Title:	Recurrence and metastasis of hepatocellular carcinoma: progress and prospects.
Author:	Zhou, Xin-Da
PMID:	14607620

69.
Journal:	World J Gastroenterol. 2003 Jan;9(1):84-8.
Title:	Effects of p16 gene on biological behaviours in hepatocellular carcinoma cells.
Author:	Huang, Jian-Zhao\|Xia, Sui-Sheng\|Ye, Qi-Fa\|Jiang, Han-Ying\|Chen, Zhong-Hua
PMID:	12508357

70.
Journal:	Ai Zheng. 2003 Jan;22(1):46-9.
Title:	[Influence of p16 gene on the biological behavior of human hepatocellular carcinoma].
Author:	Huang, Jian-Zhao\|Xia, Sui-Sheng\|Ye, Qi-Fa\|Jiang, Han-Ying
PMID:	12561435

71.
Journal:	Cancer Lett. 2003 Feb 20;190(2):213-9.
Title:	p16 Hypermethylation in the early stage of hepatitis B virus-associated hepatocarcinogenesis.
Author:	Shim, Yhong-Hee\|Yoon, Ghil-Suk\|Choi, Hae-Jung\|Chung, Young Hwa\|Yu, Eunsil
PMID:	12565176

72.
Journal:	Oncogene. 2003 Mar 27;22(12):1866-71.
Title:	Frequent epigenetic inactivation of the RASSF1A gene in hepatocellular carcinoma.
Author:	Schagdarsurengin, Undraga\|Wilkens, Ludwig\|Steinemann, Doris\|Flemming, Peer\|Kreipe, Hans H\|Pfeifer, Gerd P\|Schlegelberger, Brigitte\|Dammann, Reinhard
PMID:	12660822

73.
Journal:	Hepatology. 2003 Apr;37(4):852-61.
Title:	Homozygous deletion scanning in hepatobiliary tumor cell lines reveals alternative pathways for liver carcinogenesis.
Author:	Pineau, Pascal\|Marchio, Agnes\|Nagamori, Seishi\|Seki, Shuichi\|Tiollais, Pierre\|Dejean, Anne
PMID:	12668978

74.
Journal:	Mech Ageing Dev. 2003 May;124(5):697-708.
Title:	Spectrum of molecular changes during hepatocarcinogenesis induced by DEN and other chemicals in Fisher 344 male rats [Mechanisms of Ageing and Development 123 (2002) 1665-1680].
Author:	Lim, In Kyoung
PMID:	12825548

75.
Journal:	Liver Transpl. 2003 Jul;9(7):664-71.
Title:	Genotyping of hepatocellular carcinoma in liver transplant recipients adds predictive power for determining recurrence-free survival.
Author:	Marsh, J Wallis\|Finkelstein, Sydney D\|Demetris, Anthony J\|Swalsky, Patricia A\|Sasatomi, Eizaburo\|Bandos, Andriy\|Subotin, Michael\|Dvorchik, Igor
PMID:	12827550

76.
Journal:	Ai Zheng. 2003 Jul;22(7):680-5.
Title:	[Determination of expression of eight p53-related genes in hepatocellular carcinoma with tissue microarrays].
Author:	Zhu, Ming-Hua\|Ni, Can-Rong\|Zhu, Zhi\|Li, Fang-Mei\|Zhang, Shun-Min
PMID:	12866955

77.
Journal:	Zhonghua Zhong Liu Za Zhi. 2003 Jul;25(4):356-8.
Title:	[Effect of p16 gene on carcinogenesis of hepatitis B virus related hepatocellular carcinoma].
Author:	Wang, Zhao-wen\|Peng, Zhi-hai\|Li, Ke\|Qiu, Guo-qiang\|Zhang, Yi\|Gu, Wei
PMID:	12921565

78.
Journal:	Am J Pathol. 2003 Sep;163(3):1101-7.
Title:	Aberrant promoter methylation profiles of tumor suppressor genes in hepatocellular carcinoma.
Author:	Yang, Bin\|Guo, Mingzhou\|Herman, James G\|Clark, Douglas P
PMID:	12937151

79.
Journal:	Carcinogenesis. 2003 Nov;24(11):1729-36.
Title:	Over-expression of Id-1 induces cell proliferation in hepatocellular carcinoma through inactivation of p16INK4a/RB pathway.
Author:	Lee, Terence Kin-Wah\|Man, Kwan\|Ling, Ming-Tat\|Wang, Xiang-Hong\|Wong, Yong-Chuan\|Lo, Chung-Mau\|Poon, Ronnie Tung-Ping\|Ng, Irene Oi-Lin\|Fan, Sheung-Tat
PMID:	12949053

80.
Journal:	Cancer Genet Cytogenet. 2003 Oct 1;146(1):8-15.
Title:	Clinicopathologic significance of genetic alterations in hepatocellular carcinoma.
Author:	Pang, A\|Ng, I O\|Fan, S T\|Kwong, Y L
PMID:	14499690

81.
Journal:	Am J Pathol. 2003 Oct;163(4):1371-8.
Title:	Aberrant CpG island hypermethylation along multistep hepatocarcinogenesis.
Author:	Lee, Sun\|Lee, Hyeon Joo\|Kim, Jae-Hoon\|Lee, Hyo-Suk\|Jang, Ja June\|Kang, Gyeong Hoon
PMID:	14507645

82.
Journal:	J Okla State Med Assoc. 2003 Oct;96(10):485-94.
Title:	Gene activity associated with cancers treated by surgical oncologists.
Author:	Brackett, Daniel J\|Smith, Brenda J\|Lerner, Megan R\|Hanas, Jay S\|Postier, Russell G
PMID:	14619604

83.
Journal:	Cell Res. 2003 Oct;13(5):319-33.
Title:	Methylation profiling of twenty four genes and the concordant methylation behaviours of nineteen genes that may contribute to hepatocellular carcinogenesis.
Author:	Yu, Jian\|Zhang, Hong Yu\|Ma, Zhen Zhong\|Lu, Wei\|Wang, Yi Fei\|Zhu, Jing De
PMID:	14672555

84.
Journal:	J Gastroenterol Hepatol. 2004 Apr;19(4):397-405.
Title:	p16INK4A gene alterations are not a prognostic indicator for survival in patients with hepatocellular carcinoma undergoing curative hepatectomy.
Author:	Anzola, Monica\|Cuevas, Nerea\|Lopez-Martinez, Monica\|Martinez de Pancorbo, Marian\|Burgos, Juan Jose
PMID:	15012776

85.
Journal:	Clin Cancer Res. 2004 Mar 15;10(6):2150-7.
Title:	Orthotopic implantation of human hepatocellular carcinoma in mice: analysis of tumor progression and establishment of the BCLC-9 cell line.
Author:	Armengol, Carolina\|Tarafa, Gemma\|Boix, Loreto\|Sole, Manel\|Queralt, Rosa\|Costa, Dolors\|Bachs, Oriol\|Bruix, Jordi\|Capella, Gabriel
PMID:	15041736

86.
Journal:	Zhonghua Yi Xue Za Zhi. 2004 Feb 2;84(3):225-8.
Title:	[The effects of p16 and Rb protein expression and NF-kappaB activity on hepatocarcinogenesis].
Author:	Wang, Zhao-wen\|Peng, Zhi-hai\|Tang, Hua-mei\|Qiu, Guo-qiang\|Xing, Tong-hai\|Yang, Ming-zhi
PMID:	15059540

87.
Journal:	Scand J Gastroenterol. 2004 Mar;39(3):246-51.
Title:	Patterns of methylation profiles as diagnostic markers for multiple hepatocellular carcinomas.
Author:	Anzola, M\|Cuevas, N\|Lopez-Martinez, M\|Martinez de Pancorbo, M\|Burgos, J J
PMID:	15074394

88.
Journal:	Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2004 Apr;21(2):132-7.
Title:	[Impact of p16INK4A and p15INK4B on human hepatocellular carcinoma cell proliferation and apoptosis].
Author:	Qin, Yang\|Liu, Jian-yu\|Li, Bo\|Peng, Wen-zhen\|Fu, Ming-de\|Sun, Zhi-lin\|Sun, Ze-fang
PMID:	15079795

89.
Journal:	Genes Dev. 2004 Apr 1;18(7):830-50.
Title:	Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor.
Author:	Kalinichenko, Vladimir V\|Major, Michael L\|Wang, Xinhe\|Petrovic, Vladimir\|Kuechle, Joseph\|Yoder, Helena M\|Dennewitz, Margaret B\|Shin, Brian\|Datta, Abhishek\|Raychaudhuri, Pradip\|Costa, Robert H
PMID:	15082532

90.
Journal:	Eur J Gastroenterol Hepatol. 2004 Jan;16(1):19-26.
Title:	P14ARF gene alterations in human hepatocellular carcinoma.
Author:	Anzola, Monica\|Cuevas, Nerea\|Lopez-Martinez, Monica\|Saiz, Alberto\|Burgos, Juan Jose\|Martinez de Pancorboa, Marian
PMID:	15095848

91.
Journal:	J Gastroenterol. 2004;39(4):355-61.
Title:	Alteration of the p14(ARF) gene and p53 status in human hepatocellular carcinomas.
Author:	Ito, Teruaki\|Nishida, Naoshi\|Fukuda, Yoshihiro\|Nishimura, Takafumi\|Komeda, Toshiki\|Nakao, Kazuwa
PMID:	15168247

92.
Journal:	AJR Am J Roentgenol. 2004 Aug;183(2):383-5.
Title:	Does percutaneous liver biopsy of hepatocellular carcinoma cause hematogenous dissemination? An in vivo study with quantitative assay of circulating tumor DNA using methylation-specific real-time polymerase chain reaction.
Author:	Yu, Simon Chun Ho\|Lo, Dennis Yuk Ming\|Ip, Chei Bing\|Liew, Choong Tsek\|Leung, Thomas Wai Tong\|Lau, Wan Yee
PMID:	15269029

93.
Journal:	Hepatology. 2004 Sep;40(3):677-86.
Title:	Reduced expression of cell cycle regulator p18(INK4C) in human hepatocellular carcinoma.
Author:	Morishita, Asahiro\|Masaki, Tsutomu\|Yoshiji, Hitoshi\|Nakai, Seiji\|Ogi, Tomohiro\|Miyauchi, Yoshiaki\|Yoshida, Shuhei\|Funaki, Toshiharu\|Uchida, Naohito\|Kita, Yuko\|Funakoshi, Fumi\|Usuki, Hisashi\|Okada, Setsuo\|Izuishi, Kunihiko\|Watanabe, Seishiro\|Kurokohchi, Ka
PMID:	15349907

94.
Journal:	Hum Pathol. 2004 Dec;35(12):1505-14.
Title:	Frequent p16ink4a inactivation is an early and frequent event of intraductal papillary neoplasm of the liver arising in hepatolithiasis.
Author:	Ishikawa, Akira\|Sasaki, Motoko\|Sato, Yasunori\|Ohira, Shusaku\|Chen, Miin-Fu\|Huang, Shiu-Feng\|Oda, Koji\|Nimura, Yuji\|Nakanuma, Yasuni
PMID:	15619210

95.
Journal:	Virology. 2005 Feb 5;332(1):130-44.
Title:	Molecular profiling of early stage liver fibrosis in patients with chronic hepatitis C virus infection.
Author:	Bieche, Ivan\|Asselah, Tarik\|Laurendeau, Ingrid\|Vidaud, Dominique\|Degot, Claude\|Paradis, Valerie\|Bedossa, Pierre\|Valla, Dominique-Charles\|Marcellin, Patrick\|Vidaud, Michel
PMID:	15661146

96.
Journal:	Curr Opin Genet Dev. 2005 Feb;15(1):42-8.
Title:	New and unexpected: forkhead meets ARF.
Author:	Costa, Robert H\|Kalinichenko, Vladimir V\|Major, Michael L\|Raychaudhuri, Pradip
PMID:	15661532

97.
Journal:	Oncol Rep. 2005 Mar;13(3):433-8.
Title:	Abnormal expression of JUNB gene in hepatocellular carcinoma.
Author:	Chang, Ya-Sian\|Yeh, Kun-Tu\|Yang, Ming-Yu\|Liu, Ta-Chih\|Lin, Sheng-Fung\|Chan, Wen-Ling\|Chang, Jan-Gowth
PMID:	15706412

98.
Journal:	Int J Cancer. 2005 Jul 20;115(6):903-10.
Title:	Lithium-mediated downregulation of PKB/Akt and cyclin E with growth inhibition in hepatocellular carcinoma cells.
Author:	Erdal, Esra\|Ozturk, Nuri\|Cagatay, Tolga\|Eksioglu-Demiralp, Emel\|Ozturk, Mehmet
PMID:	15723355

99.
Journal:	Cancer Genet Cytogenet. 2005 Apr 15;158(2):172-9.
Title:	Establishment of a cell line from a malignant rhabdoid tumor of the liver lacking the function of two tumor suppressor genes, hSNF5/INI1 and p16.
Author:	Kuroda, Hiroshi\|Moritake, Hiroshi\|Sawada, Kazumi\|Kuwahara, Yasumichi\|Imoto, Issei\|Inazawa, Johji\|Sugimoto, Tohru
PMID:	15796965

100.
Journal:	Acta Histochem. 2005;107(3):161-71.
Title:	Cell biological evaluation of liver cell carcinoma, dysplasia and adenoma by tissue micro-array analysis.
Author:	van Dekken, Herman\|Verhoef, Cees\|Wink, Josiane\|van Marion, Ronald\|Vissers, Kees J\|Hop, Wim C J\|de Man, Rob A\|IJzermans, Jan N\|van Eijck, Casper H J\|Zondervan, Pieter E
PMID:	16000213

101.
Journal:	J Biol Chem. 2005 Sep 9;280(36):31548-56.
Title:	Hepatocyte growth factor induces redistribution of p21(CIP1) and p27(KIP1) through ERK-dependent p16(INK4a) up-regulation, leading to cell cycle arrest at G1 in HepG2 hepatoma cells.
Author:	Han, Junhong\|Tsukada, Yu-ichi\|Hara, Eiji\|Kitamura, Naomi\|Tanaka, Toshiaki
PMID:	16014626

102.
Journal:	Tumour Biol. 2005 Nov-Dec;26(6):300-5.
Title:	Effect of promoter methylation of the p16 gene on phosphorylation of retinoblastoma gene product and growth of hepatocellular carcinoma cells.
Author:	Maeta, Yoshiko\|Shiota, Goshi\|Okano, Jun-ichi\|Murawaki, Yoshikazu
PMID:	16254459

103.
Journal:	Biochem Biophys Res Commun. 2005 Dec 23;338(3):1353-8.
Title:	Methylation-based molecular margin analysis in hepatocellular carcinoma.
Author:	Yang, Bin\|Gao, Ying-Tang\|Du, Zhi\|Zhao, Lei\|Song, Wen-Qin
PMID:	16269133

104.
Journal:	Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):17059-64.
Title:	Somatic integration of an oncogene-harboring Sleeping Beauty transposon models liver tumor development in the mouse.
Author:	Carlson, Corey M\|Frandsen, Joel L\|Kirchhof, Nicole\|McIvor, R Scott\|Largaespada, David A
PMID:	16286660

105.
Journal:	Sichuan Da Xue Xue Bao Yi Xue Ban. 2005 Nov;36(6):834-8.
Title:	[Growth inhibition and demethylation by a component of natural drug, CDP, in cancer cell lines].
Author:	Luan, Ju\|Qin, Yang\|Xu, Dan\|Sun, Zhi-Lin\|Sun, Ze-Fang
PMID:	16334566

106.
Journal:	Liver Int. 2005 Dec;25(6):1209-16.
Title:	Methylation status of p14ARF, p15INK4b, and p16INK4a genes in human hepatocellular carcinoma.
Author:	Fukai, Kenichi\|Yokosuka, Osamu\|Imazeki, Fumio\|Tada, Motohisa\|Mikata, Rintaro\|Miyazaki, Masaru\|Ochiai, Takenori\|Saisho, Hiromitsu
PMID:	16343074

107.
Journal:	Se Pu. 2005 Sep;23(5):456-63.
Title:	[Laboratory on a microfluidic chip].
Author:	Lin, Bingcheng\|Qin, Jianhua
PMID:	16350786

108.
Journal:	Clin Biochem Rev. 2005 Aug;26(3):65-79.
Title:	Recent developments in the first detection of hepatocellular carcinoma.
Author:	Lopez, Joseph B
PMID:	16450014

109.
Journal:	Cancer Lett. 2006 Feb 28;233(2):271-8.
Title:	DNA methyltransferase expression and DNA hypermethylation in human hepatocellular carcinoma.
Author:	Park, Hye-Jung\|Yu, Eunsil\|Shim, Yhong-Hee
PMID:	15885882

110.
Journal:	Carcinogenesis. 2006 Jan;27(1):64-72.
Title:	Promoter-hypermethylation is causing functional relevant downregulation of methylthioadenosine phosphorylase (MTAP) expression in hepatocellular carcinoma.
Author:	Hellerbrand, Claus\|Muhlbauer, Marcus\|Wallner, Susanne\|Schuierer, Marion\|Behrmann, Iris\|Bataille, Frauke\|Weiss, Thomas\|Scholmerich, Jurgen\|Bosserhoff, Anja-Katrin
PMID:	16081515

111.
Journal:	Oncol Rep. 2006 Feb;15(2):507-11.
Title:	Aberrant methylation of EDNRB and p16 genes in hepatocellular carcinoma (HCC) in Taiwan.
Author:	Hsu, Li-Sung\|Lee, Hsin-Chen\|Chau, Gar-Yang\|Yin, Pen-Hui\|Chi, Chin-Wen\|Lui, Wing Yiu
PMID:	16391877

112.
Journal:	Am J Pathol. 2006 Apr;168(4):1375-84.
Title:	Epigenetic instability and chromosomal instability in hepatocellular carcinoma.
Author:	Katoh, Hiroto\|Shibata, Tatsuhiro\|Kokubu, Akiko\|Ojima, Hidenori\|Fukayama, Masashi\|Kanai, Yae\|Hirohashi, Setsuo
PMID:	16565510

113.
Journal:	Life Sci. 2006 Aug 15;79(12):1129-39.
Title:	Ganoderiol F, a ganoderma triterpene, induces senescence in hepatoma HepG2 cells.
Author:	Chang, Ue-Min\|Li, Chyi-Hann\|Lin, Liang-In\|Huang, Cheng-Po\|Kan, Lou-Sing\|Lin, Shwu-Bin
PMID:	16635496

114.
Journal:	Int J Cancer. 2006 Oct 1;119(7):1553-7.
Title:	Dietary folate is associated with p16(INK4A) methylation in head and neck squamous cell carcinoma.
Author:	Kraunz, Kim S\|Hsiung, Debra\|McClean, Michael D\|Liu, Mei\|Osanyingbemi, Joyce\|Nelson, Heather H\|Kelsey, Karl T
PMID:	16646054

115.
Journal:	J Gastroenterol Hepatol. 2006 Jan;21(1 Pt 1):15-21.
Title:	Review of genetic and epigenetic alterations in hepatocarcinogenesis.
Author:	Herath, Nirmitha I\|Leggett, Barbara A\|MacDonald, Graeme A
PMID:	16706806

116.
Journal:	Ai Zheng. 2006 Jun;25(6):696-700.
Title:	[Correlations of CpG island methylator phenotype and OPCML gene methylation to carcinogenesis of hepatocellular carcinoma].
Author:	Liu, Wen-Ji\|Wang, Li\|Wang, Jian-Ping\|Li, Jin-Qing\|Zhang, Chang-Qin\|Zheng, Lie\|Yuan, Yun-Fei
PMID:	16764763

117.
Journal:	Ai Zheng. 2006 Jul;25(7):798-804.
Title:	[Construction and study of replication-defective adenovirus targeting hepatocarcinoma].
Author:	Xu, Ding-Yao\|Du, Zhi-Yan\|Wang, Yan\|Chen, Hui-Hua\|Xu, Yuan-Ji\|Lu, Ying-Lin
PMID:	16831267

118.
Journal:	Oncol Rep. 2006 Nov;16(5):1105-10.
Title:	Humoral immune response to p16, a cyclin-dependent kinase inhibitor in human malignancies.
Author:	Looi, Koksun\|Megliorino, Roxanne\|Shi, Fu-Dong\|Peng, Xuan-Xian\|Chen, Yao\|Zhang, Jian-Ying
PMID:	17016600

119.
Journal:	Med Mol Morphol. 2006 Dec;39(4):169-75.
Title:	p16 and p27 are functionally correlated during the progress of hepatocarcinogenesis.
Author:	Matsuda, Yasunobu\|Ichida, Takafumi
PMID:	17187177

120.
Journal:	J Hepatol. 2007 Jan;46(1):107-14.
Title:	Antibody detection using tumor-associated antigen mini-array in immunodiagnosing human hepatocellular carcinoma.
Author:	Zhang, Jian-Ying\|Megliorino, Roxanne\|Peng, Xuan-Xian\|Tan, Eng M\|Chen, Yao\|Chan, Edward K L
PMID:	17067715

121.
Journal:	Oncogene. 2007 May 17;26(23):3395-405.
Title:	PDGF essentially links TGF-beta signaling to nuclear beta-catenin accumulation in hepatocellular carcinoma progression.
Author:	Fischer, A N M\|Fuchs, E\|Mikula, M\|Huber, H\|Beug, H\|Mikulits, W
PMID:	17130832

122.
Journal:	Hepatology. 2007 Jan;45(1):42-52.
Title:	Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets.
Author:	Boyault, Sandrine\|Rickman, David S\|de Reynies, Aurelien\|Balabaud, Charles\|Rebouissou, Sandra\|Jeannot, Emmanuelle\|Herault, Aurelie\|Saric, Jean\|Belghiti, Jacques\|Franco, Dominique\|Bioulac-Sage, Paulette\|Laurent-Puig, Pierre\|Zucman-Rossi, Jessica
PMID:	17187432

123.
Journal:	Clin Cancer Res. 2007 Feb 1;13(3):944-52.
Title:	CpG island methylator phenotype association with elevated serum alpha-fetoprotein level in hepatocellular carcinoma.
Author:	Zhang, Changsong\|Li, Zhengyou\|Cheng, Yue\|Jia, Fengqi\|Li, Rong\|Wu, Mengchao\|Li, Ke\|Wei, Lixin
PMID:	17289889

124.
Journal:	Sichuan Da Xue Xue Bao Yi Xue Ban. 2007 Jan;38(1):53-6.
Title:	[Research on promoter region methylation status of tumor repressor gene P16 in human hepatocellular carcinoma by using methylation sensitive restriction enzyme and semi-nested PCR assay].
Author:	Jiang, Lei\|Qin, Yang\|Sun, Zhi-lin\|Sun, Ze-fang\|Wang, Jin-hong\|Yang, Lu-chuan
PMID:	17294727

125.
Journal:	Hum Mol Genet. 2007 Jun 1;16(11):1335-42.
Title:	Epigenetic defects of hepatocellular carcinoma are already found in non-neoplastic liver cells from patients with hereditary haemochromatosis.
Author:	Lehmann, Ulrich\|Wingen, Luzie U\|Brakensiek, Kai\|Wedemeyer, Heiner\|Becker, Thomas\|Heim, Albert\|Metzig, Kathleen\|Hasemeier, Britta\|Kreipe, Hans\|Flemming, Peer
PMID:	17412760

126.
Journal:	Clin Cancer Res. 2007 Apr 15;13(8):2378-84.
Title:	Predicting hepatocellular carcinoma by detection of aberrant promoter methylation in serum DNA.
Author:	Zhang, Yu-Jing\|Wu, Hui-Chen\|Shen, Jing\|Ahsan, Habibul\|Tsai, Wei Yann\|Yang, Hwai-I\|Wang, Li-Yu\|Chen, Shu-Yuan\|Chen, Chien-Jen\|Santella, Regina M
PMID:	17438096

127.
Journal:	Int J Mol Med. 2007 Jul;20(1):65-73.
Title:	DNA methyltransferase expression and DNA methylation in human hepatocellular carcinoma and their clinicopathological correlation.
Author:	Oh, Bong-Kyeong\|Kim, Haeryoung\|Park, Hye-Jung\|Shim, Yhong-Hee\|Choi, Jinsub\|Park, Chanil\|Park, Young Nyun
PMID:	17549390

128.
Journal:	Hepatol Res. 2007 Nov;37(11):974-83.
Title:	Alterations of DNA methylation and histone modifications contribute to gene silencing in hepatocellular carcinomas.
Author:	Kondo, Yutaka\|Shen, Lanlan\|Suzuki, Seiji\|Kurokawa, Tsuyoshi\|Masuko, Kazuo\|Tanaka, Yasuhito\|Kato, Hideaki\|Mizuno, Yoshiki\|Yokoe, Masamichi\|Sugauchi, Fuminaka\|Hirashima, Noboru\|Orito, Etsuro\|Osada, Hirotaka\|Ueda, Ryuzo\|Guo, Yi\|Chen, Xinli\|Issa, Jean-Pierre
PMID:	17584191

129.
Journal:	Zhonghua Zhong Liu Za Zhi. 2007 Mar;29(3):166-70.
Title:	[Chronic hepatitis B virus infection and the methylation status of p16INK4A promoter].
Author:	Zhu, Rong\|Li, Bai-zhou\|Ling, Yu-qin\|Zhang, Hui-ping\|Li, Hua\|Liu, Ye\|Hu, Xi-qi\|Zhu, Hong-guang
PMID:	17649629

130.
Journal:	J Mol Diagn. 2007 Sep;9(4):510-20.
Title:	Rapid identification of promoter hypermethylation in hepatocellular carcinoma by pyrosequencing of etiologically homogeneous sample pools.
Author:	Dejeux, Emelyne\|Audard, Virginie\|Cavard, Catherine\|Gut, Ivo Glynne\|Terris, Benoit\|Tost, Jorg
PMID:	17690210

131.
Journal:	Cancer Res. 2007 Aug 15;67(16):7589-96.
Title:	Loss of p53 and Ink4a/Arf cooperate in a cell autonomous fashion to induce metastasis of hepatocellular carcinoma cells.
Author:	Chen, Ya-Wen\|Klimstra, David S\|Mongeau, Michelle E\|Tatem, Jessica L\|Boyartchuk, Victor\|Lewis, Brian C
PMID:	17699762

132.
Journal:	Oncol Rep. 2007 Nov;18(5):1225-30.
Title:	Detection of promoter hypermethylation in serum samples of cancer patients by methylation-specific polymerase chain reaction for tumour suppressor genes including RUNX3.
Author:	Tan, Sing-Huang\|Ida, Hiroshi\|Lau, Quek-Choon\|Goh, Boon-Cher\|Chieng, Wei-Shieng\|Loh, Marie\|Ito, Yoshiaki
PMID:	17914577

133.
Journal:	Br J Cancer. 2007 Nov 5;97(9):1260-5.
Title:	Hypermethylation of multiple genes as clonal markers in multicentric hepatocellular carcinoma.
Author:	Nomoto, S\|Kinoshita, T\|Kato, K\|Otani, S\|Kasuya, H\|Takeda, S\|Kanazumi, N\|Sugimoto, H\|Nakao, A
PMID:	17968429

134.
Journal:	Curr Pharm Des. 2007;13(32):3279-87.
Title:	Molecular pathways and related target therapies in liver carcinoma.
Author:	Tommasi, S\|Pinto, R\|Pilato, B\|Paradiso, A
PMID:	18045179

135.
Journal:	Cancer Invest. 2007 Dec;25(8):668-77.
Title:	Telomere length in hepatocellular carcinoma and paired adjacent non-tumor tissues by quantitative PCR.
Author:	Zhang, Yujing\|Shen, Jing\|Ming-Whei\|Lee, Yu Po-Huang\|Santella, Regina M
PMID:	18058461

136.
Journal:	World J Gastroenterol. 2007 Dec 14;13(46):6249-53.
Title:	Effects of endogenous nitric oxide induced by 5-fluorouracil and L-Arg on liver carcinoma in nude mice.
Author:	Yin, Xiao-Yan\|Jiang, Jun-Mei\|Liu, Ji-Yong\|Zhu, Ju-Ren
PMID:	18069768

137.
Journal:	Proteomics Clin Appl. 2007 Apr;1(4):410-9.
Title:	Anticancer effects of aloe-emodin on HepG2 cells: Cellular and proteomic studies.
Author:	Lu, Guo Dong\|Shen, Han-Ming\|Ong, Choon Nam\|Chung, Maxey C M
PMID:	21136693

138.
Journal:	J Biol Chem. 2008 Jan 18;283(3):1428-36.
Title:	Coupling of Grb2 to Gab1 mediates hepatocyte growth factor-induced high intensity ERK signal required for inhibition of HepG2 hepatoma cell proliferation.
Author:	Kondo, Asuka\|Hirayama, Naoki\|Sugito, Yasuko\|Shono, Michihiro\|Tanaka, Toshiaki\|Kitamura, Naomi
PMID:	18003605

139.
Journal:	J Cell Biochem. 2008 May 1;104(1):176-88.
Title:	Up-regulation of p21CIP1 expression mediated by ERK-dependent and -independent pathways contributes to hepatocyte growth factor-induced inhibition of HepG2 hepatoma cell proliferation.
Author:	Shirako, Erika\|Hirayama, Naoki\|Tsukada, Yu-ichi\|Tanaka, Toshiaki\|Kitamura, Naomi
PMID:	18004740

140.
Journal:	Hepatology. 2008 Mar;47(3):908-18.
Title:	Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma.
Author:	Nishida, Naoshi\|Nagasaka, Takeshi\|Nishimura, Takafumi\|Ikai, Iwao\|Boland, C Richard\|Goel, Ajay
PMID:	18161048

141.
Journal:	Cancer Res. 2008 Jan 15;68(2):476-82.
Title:	p19Arf inhibits the invasion of hepatocellular carcinoma cells by binding to C-terminal binding protein.
Author:	Chen, Ya-Wen\|Paliwal, Seema\|Draheim, Kyle\|Grossman, Steven R\|Lewis, Brian C
PMID:	18199542

142.
Journal:	Mod Pathol. 2008 Jun;21(6):670-5.
Title:	Epigenetic instability is rare in fibrolamellar carcinomas but common in viral-associated hepatocellular carcinomas.
Author:	Vivekanandan, Perumal\|Torbenson, Michael
PMID:	18264082

143.
Journal:	Dig Surg. 2008;25(1):21-6.
Title:	Somatostatin receptor in human hepatocellular carcinomas: biological, patient and tumor characteristics.
Author:	Verhoef, C\|van Dekken, H\|Hofland, L J\|Zondervan, P E\|de Wilt, J H W\|van Marion, R\|de Man, R A\|IJzermans, J N M\|van Eijck, C H J
PMID:	18292657

144.
Journal:	World J Gastroenterol. 2008 Mar 21;14(11):1734-40.
Title:	Molecular mechanism underlying the functional loss of cyclindependent kinase inhibitors p16 and p27 in hepatocellular carcinoma.
Author:	Matsuda, Yasunobu
PMID:	18350604

145.
Journal:	Int J Cancer. 2008 Jun 15;122(12):2800-4.
Title:	Quantitative promoter methylation analysis of hepatocellular carcinoma, cirrhotic and normal liver.
Author:	Harder, Jan\|Opitz, Oliver G\|Brabender, Jan\|Olschewski, Manfred\|Blum, Hubert E\|Nomoto, Shuji\|Usadel, Henning
PMID:	18351580

146.
Journal:	Int J Cancer. 2008 Sep 1;123(5):998-1004.
Title:	CpG island methylator phenotype association with upregulated telomerase activity in hepatocellular carcinoma.
Author:	Zhang, Changsong\|Guo, Xianling\|Jiang, Guocheng\|Zhang, Li\|Yang, Yang\|Shen, Feng\|Wu, Mengchao\|Wei, Lixin
PMID:	18546260

147.
Journal:	Carcinogenesis. 2008 Oct;29(10):1901-10.
Title:	Variable DNA methylation patterns associated with progression of disease in hepatocellular carcinomas.
Author:	Gao, Wentao\|Kondo, Yutaka\|Shen, Lanlan\|Shimizu, Yasuhiro\|Sano, Tsuyoshi\|Yamao, Kenji\|Natsume, Atsushi\|Goto, Yasuhiro\|Ito, Motokazu\|Murakami, Hideki\|Osada, Hirotaka\|Zhang, Jiexin\|Issa, Jean-Pierre J\|Sekido, Yoshitaka
PMID:	18632756

148.
Journal:	Cancer Res. 2008 Oct 1;68(19):7742-9.
Title:	The polycomb gene product BMI1 contributes to the maintenance of tumor-initiating side population cells in hepatocellular carcinoma.
Author:	Chiba, Tetsuhiro\|Miyagi, Satoru\|Saraya, Atsunori\|Aoki, Ryutaro\|Seki, Atsuyoshi\|Morita, Yohei\|Yonemitsu, Yutaka\|Yokosuka, Osamu\|Taniguchi, Hideki\|Nakauchi, Hiromitsu\|Iwama, Atsushi
PMID:	18829528

149.
Journal:	Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2008 Oct;25(5):534-7.
Title:	[Detection of methylation in hepatocellular carcinoma using SYBR Green fluorescent quantitative PCR].
Author:	Yang, Bin\|Lou, Cheng\|Gao, Yingtang\|Du, Zhi\|Song, Wenqin
PMID:	18841566

150.
Journal:	Acta Biochim Biophys Sin (Shanghai). 2008 Nov;40(11):970-8.
Title:	Nidus vespae protein inhibiting proliferation of HepG2 hepatoma cells through extracellular signal-regulated kinase signaling pathways and inducing G1 cell cycle arrest.
Author:	Wang, Changdong\|Chen, Peng\|Jin, Hongjuan\|Yan, Xu\|Gan, Lu\|Li, Yi\|Zhou, Shiyi\|Chang, Junli\|Wang, Yuesheng\|Yang, Guangxiao\|He, Guangyuan
PMID:	18989579

151.
Journal:	World J Gastroenterol. 2008 Nov 7;14(41):6339-46.
Title:	c-Fos overexpression increases the proliferation of human hepatocytes by stabilizing nuclear Cyclin D1.
Author:	Guller, Meryem\|Toualbi-Abed, Kahina\|Legrand, Agnes\|Michel, Laurence\|Mauviel, Alain\|Bernuau, Dominique\|Daniel, Fanny
PMID:	19009649

152.
Journal:	Eur J Gastroenterol Hepatol. 2008 Nov;20(11):1077-84.
Title:	Biological characteristics of fluorescent protein-expressing human hepatocellular carcinoma xenograft model in nude mice.
Author:	Yang, Bi-Wei\|Liang, Ying\|Xia, Jing-Lin\|Sun, Hui-Chuan\|Wang, Lu\|Zhang, Ju-Bo\|Tang, Zhao-You\|Liu, Kang-Da\|Chen, Jie\|Xue, Qiong\|Chen, Jun\|Gao, Dong-Mei\|Wu, Wei-Zhong
PMID:	19047839

153.
Journal:	Zhonghua Zhong Liu Za Zhi. 2008 Nov;30(11):831-6.
Title:	[Aberrant methylation of multiple genes and its clinical implication in hepatocellular carcinoma].
Author:	Lou, Cheng\|Yang, Bin\|Gao, Ying-tang\|Wang, Yi-jun\|Nie, Fu-hua\|Yuan, Qiang\|Zhang, Chun-li\|Du, Zhi
PMID:	19173828

154.
Journal:	Dig Dis Sci. 2009 Jan;54(1):80-8.
Title:	Progression of hypermethylation of the p16(INK4A) gene from normal liver to nontumorous liver and hepatocellular carcinoma: an evaluation using quantitative PCR analysis.
Author:	Kurita, So\|Ohkoshi, Shogo\|Yano, Masahiko\|Yamazaki, Kazuhide\|Suzuki, Kenta\|Aoki, Yo-hei\|Matsuda, Yasunobu\|Wakai, Toshifumi\|Shirai, Yoshio\|Ichida, Takafumi\|Aoyagi, Yutaka
PMID:	19016326

155.
Journal:	Toxicology. 2009 Feb 27;256(3):143-51.
Title:	Changes in gene expression and assessment of DNA methylation in primary human hepatocytes and HepG2 cells exposed to the environmental contaminants-Hexabromocyclododecane and 17-beta oestradiol.
Author:	Aniagu, Stanley O\|Williams, Tim D\|Chipman, J Kevin
PMID:	19027819

156.
Journal:	Cancer Lett. 2009 Mar 18;275(2):277-84.
Title:	Silencing of Hint1, a novel tumor suppressor gene, by promoter hypermethylation in hepatocellular carcinoma.
Author:	Zhang, Yu-Jing\|Li, Haiyang\|Wu, Hui-Chen\|Shen, Jing\|Wang, Lin\|Yu, Ming-Whei\|Lee, Po-Huang\|Bernard Weinstein, I\|Santella, Regina M
PMID:	19081673

157.
Journal:	Mod Pathol. 2009 Mar;22(3):442-9.
Title:	Hypomethylation of long interspersed nuclear element-1 in hepatocellular carcinomas.
Author:	Kim, Mi-Jung\|White-Cross, Jill A\|Shen, Lanlan\|Issa, Jean-Pierre J\|Rashid, Asif
PMID:	19136926

158.
Journal:	Biochem Pharmacol. 2009 Jul 1;78(1):21-32.
Title:	Down-regulation of the HGF/MET autocrine loop induced by celecoxib and mediated by P-gp in MDR-positive human hepatocellular carcinoma cell line.
Author:	Mazzanti, Roberto\|Platini, Francesca\|Bottini, Consuelo\|Fantappie, Ornella\|Solazzo, Michela\|Tessitore, Luciana
PMID:	19447220

159.
Journal:	Int J Oncol. 2009 Nov;35(5):1081-9.
Title:	Varying etiologies lead to different molecular changes in Australian and South African hepatocellular carcinomas.
Author:	Herath, Nirmitha I\|Purdie, David M\|Kew, Michael C\|Smith, Jeffery L\|Young, Joanne\|Leggett, Barbara A\|MacDonald, Graeme A
PMID:	19787262

160.
Journal:	Mol Cancer Res. 2009 Dec;7(12):1937-45.
Title:	Bmi1 functions as an oncogene independent of Ink4A/Arf repression in hepatic carcinogenesis.
Author:	Xu, Chuan-Rui\|Lee, Susie\|Ho, Coral\|Bommi, Prashant\|Huang, Shi-Ang\|Cheung, Siu Tim\|Dimri, Goberdhan P\|Chen, Xin
PMID:	19934271

161.
Journal:	Cancer Genet Cytogenet. 2009 Dec;195(2):112-9.
Title:	Methylation profiling of tumor suppressor genes and oncogenes in hepatitis virus-related hepatocellular carcinoma in northern India.
Author:	Kiran, Manjula\|Chawla, Yogesh K\|Kaur, Jyotdeep
PMID:	19963110

162.
Journal:	Viruses. 2009 Dec;1(3):852-72.
Title:	Molecular mechanisms underlying hepatocellular carcinoma.
Author:	Merle, Philippe\|Trepo, Christian
PMID:	21994573

163.
Journal:	J Viral Hepat. 2010 Feb 1;17(2):98-107.
Title:	Hepatitis B virus X protein induces hypermethylation of p16(INK4A) promoter via DNA methyltransferases in the early stage of HBV-associated hepatocarcinogenesis.
Author:	Zhu, Y-Z\|Zhu, R\|Fan, J\|Pan, Q\|Li, H\|Chen, Q\|Zhu, H-G
PMID:	19732323

164.
Journal:	Exp Mol Pathol. 2010 Feb;88(1):107-11.
Title:	Concordance of DNA methylation pattern in plasma and tumor DNA of Egyptian hepatocellular carcinoma patients.
Author:	Iyer, Priyanka\|Zekri, Abdel-Rahman\|Hung, Chu-Wei\|Schiefelbein, Emily\|Ismail, Kadry\|Hablas, Ahmed\|Seifeldin, Ibrahim A\|Soliman, Amr S
PMID:	19818350

165.
Journal:	Exp Mol Pathol. 2010 Apr;88(2):287-92.
Title:	DNA methylation changes in normal liver tissues and hepatocellular carcinoma with different viral infection.
Author:	Feng, Qinghua\|Stern, Joshua E\|Hawes, Stephen E\|Lu, Hiep\|Jiang, Mingjun\|Kiviat, Nancy B
PMID:	20079733

166.
Journal:	Ann Surg Oncol. 2010 Jul;17(7):1917-26.
Title:	CpG island methylator phenotype associated with tumor recurrence in tumor-node-metastasis stage I hepatocellular carcinoma.
Author:	Li, Binkui\|Liu, Wenji\|Wang, Li\|Li, Meixiang\|Wang, Jianping\|Huang, Liang\|Huang, Pinzhu\|Yuan, Yunfei
PMID:	20112070

167.
Journal:	Am J Transl Res. 2010 Jan 23;2(1):105-18.
Title:	Molecular genetics of hepatocellular neoplasia.
Author:	Jain, Shilpa\|Singhal, Shashideep\|Lee, Peng\|Xu, Ruliang
PMID:	20182587

168.
Journal:	Histopathology. 2010 May;56(6):683-93.
Title:	Genomic and immunophenotypical differences between hepatocellular carcinoma with and without cirrhosis.
Author:	Tretiakova, Maria S\|Shabani-Rad, Meer T\|Guggisberg, Kelly\|Hart, John\|Anders, Robert A\|Gao, Zu-Hua
PMID:	20546333

169.
Journal:	BMC Cancer. 2010 Jun 22;10:317.
Title:	Promoter methylation of CDKN2A and lack of p16 expression characterize patients with hepatocellular carcinoma.
Author:	Csepregi, Antal\|Ebert, Matthias Pa\|Rocken, Christoph\|Schneider-Stock, Regine\|Hoffmann, Juliane\|Schulz, Hans-Ulrich\|Roessner, Albert\|Malfertheiner, Peter
PMID:	20569442

170.
Journal:	Mol Carcinog. 2010 Aug;49(8):728-38.
Title:	Long-term ethanol exposure causes human liver cancer cells to become resistant to mitomycin C treatment through the inactivation of bad-mediated apoptosis.
Author:	Huang, Ching-Shui\|Lee, Yi-Ru\|Chen, Ching-Shyang\|Tu, Shih-Hsin\|Wang, Ying-Jan\|Lee, Chia-Hwa\|Chen, Li-Ching\|Chang, Hui-Wen\|Chang, Chien-Hsi\|Chih-Ming, Su\|Wu, Chih-Hsiung\|Ho, Yuan-Soon
PMID:	20623640

171.
Journal:	Hepatology. 2010 Sep;52(3):1111-23.
Title:	Bmi1 promotes hepatic stem cell expansion and tumorigenicity in both Ink4a/Arf-dependent and -independent manners in mice.
Author:	Chiba, Tetsuhiro\|Seki, Atsuyoshi\|Aoki, Ryutaro\|Ichikawa, Hitoshi\|Negishi, Masamitsu\|Miyagi, Satoru\|Oguro, Hideyuki\|Saraya, Atsunori\|Kamiya, Akihide\|Nakauchi, Hiromitsu\|Yokosuka, Osamu\|Iwama, Atsushi
PMID:	20648475

172.
Journal:	BMC Cancer. 2010 Aug 2;10:399.
Title:	Predictive value of CpG island methylator phenotype for tumor recurrence in hepatitis B virus-associated hepatocellular carcinoma following liver transplantation.
Author:	Wu, Li-Ming\|Zhang, Feng\|Zhou, Lin\|Yang, Zhe\|Xie, Hai-Yang\|Zheng, Shu-Sen
PMID:	20678188

173.
Journal:	Mutat Res. 2010 Oct 13;692(1-2):26-33.
Title:	Comparative analysis of promoter methylation and gene expression endpoints between tumorous and non-tumorous tissues from HCV-positive patients with hepatocellular carcinoma.
Author:	Formeister, Eric J\|Tsuchiya, Masato\|Fujii, Hideki\|Shpyleva, Svitlana\|Pogribny, Igor P\|Rusyn, Ivan
PMID:	20736025

174.
Journal:	Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2010 Sep;26(9):858-61.
Title:	[HCV DF protein inhibits expression of p16 and p21 in HepG(2) cells].
Author:	Wang, Hao-Peng\|Zhang, Yun\|Yang, Jing-Jing\|Wang, Jie\|Deng, Xiao-Zhao\|Xu, Ke
PMID:	20815982

175.
Journal:	BMC Cancer. 2010 Oct 6;10:530.
Title:	Genetic and epigenetic characteristics of human multiple hepatocellular carcinoma.
Author:	Taniguchi, Kazuya\|Yamada, Terumasa\|Sasaki, Yo\|Kato, Kikuya
PMID:	20923573

176.
Journal:	Gut. 2011 May;60(5):710-21.
Title:	P16 reactivation induces anoikis and exhibits antitumour potency by downregulating Akt/survivin signalling in hepatocellular carcinoma cells.
Author:	Hu, Huanzhang\|Li, Zhigang\|Chen, Jie\|Wang, Duanming\|Ma, Juming\|Wang, Weiguo\|Li, Jiang\|Wu, Hongping\|Li, Linfang\|Wu, Mengchao\|Qian, Qijun\|Chen, Jingbo\|Su, Changqing
PMID:	20971978

177.
Journal:	J Hepatol. 2011 May;54(5):939-47.
Title:	Aberrant CpG island hypermethylation in dysplastic nodules and early HCC of hepatitis B virus-related human multistep hepatocarcinogenesis.
Author:	Um, Tae-Hee\|Kim, Haeryoung\|Oh, Bong-Kyeong\|Kim, Myoung Soo\|Kim, Kyung Sik\|Jung, Guhung\|Park, Young Nyun
PMID:	21145824

178.
Journal:	J Clin Biochem Nutr. 2011 Jan;48(1):46-9.
Title:	Mysterious link between iron overload and CDKN2A/2B.
Author:	Toyokuni, Shinya
PMID:	21297911

179.
Journal:	J Cell Physiol. 2011 Jul;226(7):1934-9.
Title:	Oncosuppressor methylation: a possible key role in colon metastatic progression.
Author:	Tommasi, Stefania\|Pinto, Rosamaria\|Petriella, Daniela\|Pilato, Brunella\|Lacalamita, Rosanna\|Santini, Daniele\|Zito, Francesco\|Colucci, Giuseppe\|Paradiso, Angelo\|Silvestris, Nicola
PMID:	21506124

180.
Journal:	Zhonghua Zhong Liu Za Zhi. 2011 Apr;33(4):270-5.
Title:	[Effect of RhoC on hepatocellular carcinoma cell growth and related molecular mechanisms].
Author:	Xie, Shu-li\|Zhu, Ming-guang\|Lu, Guo-yue\|Wang, Guang-yi
PMID:	21575497

181.
Journal:	Exp Mol Pathol. 2011 Aug;91(1):455-60.
Title:	Quantitative methylation analysis of multiple genes using methylation-sensitive restriction enzyme-based quantitative PCR for the detection of hepatocellular carcinoma.
Author:	Hua, Dong\|Hu, Yu\|Wu, Yu-Yu\|Cheng, Zhi-Hong\|Yu, Jian\|Du, Xiang\|Huang, Zhao-Hui
PMID:	21600201

182.
Journal:	Am J Pathol. 2011 Aug;179(2):1050-60.
Title:	Promotion of liver and lung tumorigenesis in DEN-treated cytoglobin-deficient mice.
Author:	Thuy, Le Thi Thanh\|Morita, Takashi\|Yoshida, Kayo\|Wakasa, Kenichi\|Iizuka, Masashi\|Ogawa, Tomohiro\|Mori, Mami\|Sekiya, Yumiko\|Momen, Shinobu\|Motoyama, Hiroyuki\|Ikeda, Kazuo\|Yoshizato, Katsutoshi\|Kawada, Norifumi
PMID:	21684245

183.
Journal:	Asian Pac J Trop Med. 2011 Jun;4(6):492-7.
Title:	Pokemon reduces Bcl-2 expression through NF-kappa Bp65: A possible mechanism of hepatocellular carcinoma.
Author:	Zhao, Xinkai\|Ning, Qiaoming\|Sun, Xiaoning\|Tian, De'an
PMID:	21771706

184.
Journal:	World J Gastroenterol. 2011 Jul 7;17(25):3043-8.
Title:	P16 gene hypermethylation and hepatocellular carcinoma: a systematic review and meta-analysis.
Author:	Zang, Jia-Jie\|Xie, Feng\|Xu, Jin-Fang\|Qin, Ying-Yi\|Shen, Rong-Xi\|Yang, Jia-Mei\|He, Jia
PMID:	21799651

185.
Journal:	BMC Cancer. 2011 Oct 20;11:457.
Title:	Overexpression of hepatoma-derived growth factor in melanocytes does not lead to oncogenic transformation.
Author:	Sedlmaier, Angela\|Wernert, Nicolas\|Gallitzendorfer, Rainer\|Abouzied, Mekky M\|Gieselmann, Volkmar\|Franken, Sebastian
PMID:	22014102

186.
Journal:	PLoS One. 2011;6(11):e28103.
Title:	Aberrant regulation of HDAC2 mediates proliferation of hepatocellular carcinoma cells by deregulating expression of G1/S cell cycle proteins.
Author:	Noh, Ji Heon\|Jung, Kwang Hwa\|Kim, Jeong Kyu\|Eun, Jung Woo\|Bae, Hyun Jin\|Xie, Hong Jian\|Chang, Young Gyoon\|Kim, Min Gyu\|Park, Won Sang\|Lee, Jung Young\|Nam, Suk Woo
PMID:	22132221

187.
Journal:	Med Oncol. 2012 Sep;29(3):1802-9.
Title:	The role of RhoC in the proliferation and apoptosis of hepatocellular carcinoma cells.
Author:	Xie, Shuli\|Zhu, Mingguang\|Lv, Guoyue\|Zhang, Qiang\|Wang, Guangyi
PMID:	21674277

188.
Journal:	Am J Pathol. 2012 Jan;180(1):131-40.
Title:	KIF20A mRNA and its product MKlp2 are increased during hepatocyte proliferation and hepatocarcinogenesis.
Author:	Gasnereau, Isabelle\|Boissan, Mathieu\|Margall-Ducos, Germain\|Couchy, Gabrielle\|Wendum, Dominique\|Bourgain-Guglielmetti, Florence\|Desdouets, Chantal\|Lacombe, Marie-Lise\|Zucman-Rossi, Jessica\|Sobczak-Thepot, Joelle
PMID:	22056911

189.
Journal:	Liver Int. 2012 Mar;32(3):420-8.
Title:	Quantitative methylation analysis reveals gender and age differences in p16INK4a hypermethylation in hepatitis B virus-related hepatocellular carcinoma.
Author:	Wang, Yongfeng\|Cheng, Jin\|Xu, Chunhui\|Liu, Shuang\|Jiang, Suzhen\|Xu, Qiang\|Chen, Xiangmei\|Zhuang, Hui\|Lu, Fengmin
PMID:	22192146

190.
Journal:	Hepatology. 2012 Sep;56(3):994-1003.
Title:	Characteristic patterns of altered DNA methylation predict emergence of human hepatocellular carcinoma.
Author:	Nishida, Naoshi\|Kudo, Masatoshi\|Nagasaka, Takeshi\|Ikai, Iwao\|Goel, Ajay
PMID:	22407776

191.
Journal:	Liver Int. 2012 Aug;32(7):1064-78.
Title:	Upregulation of SATB1 promotes tumor growth and metastasis in liver cancer.
Author:	Tu, Wei\|Luo, Min\|Wang, Zhijun\|Yan, Wei\|Xia, Yujia\|Deng, Huan\|He, Jiayi\|Han, Ping\|Tian, Dean
PMID:	22583549

192.
Journal:	Apoptosis. 2012 Aug;17(8):842-51.
Title:	Apoptosis induced by 1,3,6,7-tetrahydroxyxanthone in Hepatocellular carcinoma and proteomic analysis.
Author:	Fu, Wei-ming\|Zhang, Jin-fang\|Wang, Hua\|Tan, Hong-sheng\|Wang, Wei-mao\|Chen, Shih-Chi\|Zhu, Xiao\|Chan, Tak-ming\|Tse, Ching-man\|Leung, Kwong-sak\|Lu, Gang\|Xu, Hong-xi\|Kung, Hsiang-fu
PMID:	22610480

193.
Journal:	Am J Pathol. 2012 Aug;181(2):413-22.
Title:	CDKN1C/P57 is regulated by the Notch target gene Hes1 and induces senescence in human hepatocellular carcinoma.
Author:	Giovannini, Catia\|Gramantieri, Laura\|Minguzzi, Manuela\|Fornari, Francesca\|Chieco, Pasquale\|Grazi, Gian Luca\|Bolondi, Luigi
PMID:	22705236

194.
Journal:	J Biochem. 2012 Dec;152(6):577-86.
Title:	Critical role of farnesoid X receptor for hepatocellular carcinoma cell proliferation.
Author:	Fujino, Tomofumi\|Takeuchi, Airi\|Maruko-Ohtake, Akiko\|Ohtake, Yosuke\|Satoh, Junichi\|Kobayashi, Tomonori\|Tanaka, Toshiaki\|Ito, Haruka\|Sakamaki, Ryosuke\|Kashimura, Ryo\|Ando, Ken\|Nishimaki-Mogami, Tomoko\|Ohkubo, Yasuhito\|Kitamura, Naomi\|Sato, Ryuichiro\|Kikuga
PMID:	22969091

195.
Journal:	Exp Ther Med. 2012 Jan;3(1):80-86.
Title:	Liver Yin deficiency tonifying herbal extract induces apoptosis and cell senescence in Bel-7402 human hepatocarcinoma cells.
Author:	Hu, Bing\|An, Hong-Mei\|Shen, Ke-Ping\|Xu, Ling\|DU, Qin\|Deng, Shan\|Wu, Yang
PMID:	22969849

196.
Journal:	PLoS One. 2012;7(9):e46472.
Title:	Bmi1 is required for hepatic progenitor cell expansion and liver tumor development.
Author:	Fan, Lingling\|Xu, Chuanrui\|Wang, Chunmei\|Tao, Junyan\|Ho, Coral\|Jiang, Lijie\|Gui, Bing\|Huang, Shiang\|Evert, Matthias\|Calvisi, Diego F\|Chen, Xin
PMID:	23029524

197.
Journal:	Beijing Da Xue Xue Bao Yi Xue Ban. 2012 Dec 18;44(6):932-6.
Title:	[Hepatitis B virus X protein induces malignant transformation tendency of Chang liver cells involving p16(INK4a) hypermethylation].
Author:	Lv, Wen-ping\|Zhou, Kai-lun\|Gao, Bin\|Chen, Yong-liang\|Xiang, Xin\|Su, Ming\|Dong, Jia-hong
PMID:	23247461

198.
Journal:	Hepatology. 2013 Jan;57(1):171-82.
Title:	Loss of immunity-supported senescence enhances susceptibility to hepatocellular carcinogenesis and progression in Toll-like receptor 2-deficient mice.
Author:	Lin, Heng\|Yan, Jun\|Wang, Ziyan\|Hua, Fang\|Yu, Jiaojiao\|Sun, Wei\|Li, Ke\|Liu, Hong\|Yang, Hongzhen\|Lv, Qi\|Xue, Jianfei\|Hu, Zhuo-Wei
PMID:	22859216

199.
Journal:	Biotechnol Lett. 2013 Jan;35(1):29-37.
Title:	Notch1 signaling contributes to the oncogenic effect of HBx on human hepatic cells.
Author:	Wang, Fan\|Xia, Xiumei\|Wang, Jinling\|Sun, Qian\|Luo, Jin\|Cheng, Bin
PMID:	22986536

200.
Journal:	Pathol Oncol Res. 2013 Apr;19(2):303-9.
Title:	Overexpression of MMSET is correlation with poor prognosis in hepatocellular carcinoma.
Author:	Zhou, Peng\|Wu, Lie-Lin\|Wu, Ke-Min\|Jiang, Wei\|Li, Jin-Dong\|Zhou, Le-du\|Li, Xin-Ying\|Chang, Shi\|Huang, Yun\|Tan, Hui\|Zhang, Ge-Wen\|He, Feng\|Wang, Zhi-Ming
PMID:	23225158

201.
Journal:	N Biotechnol. 2013 May 25;30(4):381-4.
Title:	Genetics and epigenetics of liver cancer.
Author:	Ozen, Cigdem\|Yildiz, Gokhan\|Dagcan, Alper Tunga\|Cevik, Dilek\|Ors, Aysegul\|Keles, Umur\|Topel, Hande\|Ozturk, Mehmet
PMID:	23392071

202.
Journal:	PLoS One. 2013;8(2):e55761.
Title:	Elucidating the landscape of aberrant DNA methylation in hepatocellular carcinoma.
Author:	Song, Min-Ae\|Tiirikainen, Maarit\|Kwee, Sandi\|Okimoto, Gordon\|Yu, Herbert\|Wong, Linda L
PMID:	23437062

203.
Journal:	Cancer Lett. 2013 Jul 28;335(2):372-9.
Title:	Hepatitis C virus Core protein overcomes all-trans retinoic acid-induced cell growth arrest by inhibiting retinoic acid receptor-beta2 expression via DNA methylation.
Author:	Lee, Hyehyeon\|Woo, Young-Ju\|Kim, Soo Shin\|Kim, Sung-Hyun\|Park, Bum-Joon\|Choi, Dongho\|Jang, Kyung Lib
PMID:	23474497

204.
Journal:	Hepatology. 2013 Aug;58(2):706-17.
Title:	Genomic landscape of copy number aberrations enables the identification of oncogenic drivers in hepatocellular carcinoma.
Author:	Wang, Kai\|Lim, Ho Yeong\|Shi, Stephanie\|Lee, Jeeyun\|Deng, Shibing\|Xie, Tao\|Zhu, Zhou\|Wang, Yuli\|Pocalyko, David\|Yang, Wei Jennifer\|Rejto, Paul A\|Mao, Mao\|Park, Cheol-Keun\|Xu, Jiangchun
PMID:	23505090

205.
Journal:	PLoS One. 2013 May 15;8(5):e64016.
Title:	Genome-wide transcriptional reorganization associated with senescence-to-immortality switch during human hepatocellular carcinogenesis.
Author:	Yildiz, Gokhan\|Arslan-Ergul, Ayca\|Bagislar, Sevgi\|Konu, Ozlen\|Yuzugullu, Haluk\|Gursoy-Yuzugullu, Ozge\|Ozturk, Nuri\|Ozen, Cigdem\|Ozdag, Hilal\|Erdal, Esra\|Karademir, Sedat\|Sagol, Ozgul\|Mizrak, Dilsa\|Bozkaya, Hakan\|Ilk, Hakki Gokhan\|Ilk, Ozlem\|Bilen, Biter\|C
PMID:	23691139

206.
Journal:	EMBO Mol Med. 2013 Sep;5(9):1367-82.
Title:	Depletion of the transcriptional coactivators megakaryoblastic leukaemia 1 and 2 abolishes hepatocellular carcinoma xenograft growth by inducing oncogene-induced senescence.
Author:	Hampl, Veronika\|Martin, Claudia\|Aigner, Achim\|Hoebel, Sabrina\|Singer, Stephan\|Frank, Natalie\|Sarikas, Antonio\|Ebert, Oliver\|Prywes, Ron\|Gudermann, Thomas\|Muehlich, Susanne
PMID:	23853104

207.
Journal:	PLoS One. 2013 Jul 24;8(7):e69389.
Title:	p16 Stimulates CDC42-dependent migration of hepatocellular carcinoma cells.
Author:	Chen, Ya-Wen\|Chu, Hsiao-Chien\|Ze-Shiang Lin\|Shiah, Wei-Jyh\|Chou, Chen-Pin\|Klimstra, David S\|Lewis, Brian C
PMID:	23894465

208.
Journal:	Ann Surg Oncol. 2013 Dec;20 Suppl 3:S684-92.
Title:	Chromobox homolog 4 is correlated with prognosis and tumor cell growth in hepatocellular carcinoma.
Author:	Wang, Boqing\|Tang, Jianjun\|Liao, Dan\|Wang, Gang\|Zhang, Meifang\|Sang, Yi\|Cao, Jingying\|Wu, Yuanzhong\|Zhang, Ruhua\|Li, Shengping\|Ding, Wei\|Zhang, Guoqing\|Kang, Tiebang
PMID:	23943028

209.
Journal:	J Clin Endocrinol Metab. 2013 Dec;98(12):E1909-17.
Title:	Shikonin inhibits thyroid cancer cell growth and invasiveness through targeting major signaling pathways.
Author:	Yang, Qi\|Ji, Meiju\|Guan, Haixia\|Shi, Bingyin\|Hou, Peng
PMID:	24106286

210.
Journal:	Zhonghua Gan Zang Bing Za Zhi. 2013 Aug;21(8):614-8.
Title:	[Hepatitis B virus X promotes HepG2 cell cycle progression and growth via downregulation expression of p16 protein].
Author:	Mai, Li\|Yang, Lin\|Kuang, Jian-yu\|Zhu, Jian-yun\|Kang, Yan-hong\|Zhang, Fu-cheng\|Xie, Qi-feng\|Gao, Zhi-liang
PMID:	24119743

211.
Journal:	Sci Rep. 2013 Dec 18;3:3538.
Title:	Identifying potential cancer driver genes by genomic data integration.
Author:	Chen, Yong\|Hao, Jingjing\|Jiang, Wei\|He, Tong\|Zhang, Xuegong\|Jiang, Tao\|Jiang, Rui
PMID:	24346768

212.
Journal:	PLoS One. 2013 Dec 13;8(12):e82426.
Title:	Mutation inactivation of Nijmegen breakage syndrome gene (NBS1) in hepatocellular carcinoma and intrahepatic cholangiocarcinoma.
Author:	Wang, Yan\|Hong, Yu\|Li, Man\|Long, Jiang\|Zhao, Yan-Ping\|Zhang, Jun-Xia\|Li, Qian\|You, Hong\|Tong, Wei-Min\|Jia, Ji-Dong\|Huang, Jian
PMID:	24349281

213.
Journal:	World J Gastroenterol. 2013 Dec 21;19(47):8873-9.
Title:	Target genes discovery through copy number alteration analysis in human hepatocellular carcinoma.
Author:	Gu, De-Leung\|Chen, Yen-Hsieh\|Shih, Jou-Ho\|Lin, Chi-Hung\|Jou, Yuh-Shan\|Chen, Chian-Feng
PMID:	24379610

214.
Journal:	Curr Pharm Des. 2014;20(1):81-7.
Title:	Proteomic-based analysis for identification of proteins involved in 5-fluorouracil resistance in hepatocellular carcinoma.
Author:	Tan, Yi\|Qin, Shukui\|Hou, Xin\|Qian, Xiujuan\|Xia, Jun\|Li, Yumei\|Wang, Rui\|Chen, Changjie\|Yang, Qingling\|Miele, Lucio\|Wu, Qiong\|Wang, Zhiwei
PMID:	23530500

215.
Journal:	Curr Pharm Des. 2014;20(11):1715-25.
Title:	Epigenetic mechanism involved in the HBV/HCV-related hepatocellular carcinoma tumorigenesis.
Author:	Rongrui, Liang\|Na, Huang\|Zongfang, Li\|Fanpu, Ji\|Shiwen, Jiang
PMID:	23888939

216.
Journal:	Am J Pathol. 2014 Mar;184(3):574-83.
Title:	The changing landscape of hepatocellular carcinoma: etiology, genetics, and therapy.
Author:	Knudsen, Erik S\|Gopal, Purva\|Singal, Amit G
PMID:	24388934

217.
Journal:	PLoS One. 2014 Jan 6;9(1):e84453.
Title:	Promoter methylation of MLH1, PMS2, MSH2 and p16 is a phenomenon of advanced-stage HCCs.
Author:	Hinrichsen, Inga\|Kemp, Matthias\|Peveling-Oberhag, Jan\|Passmann, Sandra\|Plotz, Guido\|Zeuzem, Stefan\|Brieger, Angela
PMID:	24400091

218.
Journal:	Clin Chem Lab Med. 2014 Jun;52(6):899-909.
Title:	Evaluation of INK4A promoter methylation using pyrosequencing and circulating cell-free DNA from patients with hepatocellular carcinoma.
Author:	Huang, Gengming\|Krocker, Joseph D\|Kirk, Jason L\|Merwat, Shehzad N\|Ju, Hyunsu\|Soloway, Roger D\|Wieck, Lucas R\|Li, Albert\|Okorodudu, Anthony O\|Petersen, John R\|Abdulla, Nihal E\|Duchini, Andrea\|Cicalese, Luca\|Rastellini, Cristiana\|Hu, Peter C\|Dong, Jianli
PMID:	24406287

219.
Journal:	Hepatology. 2014 Jun;59(6):2331-43.
Title:	The COP9 signalosome is a repressor of replicative stress responses and polyploidization in the regenerating liver.
Author:	Panattoni, Martina\|Maiorino, Laura\|Lukacs, Anna\|Zentilin, Lorena\|Mazza, Davide\|Sanvito, Francesca\|Sitia, Giovanni\|Guidotti, Luca G\|Pardi, Ruggero
PMID:	24452456

220.
Journal:	J Hepatobiliary Pancreat Sci. 2014 Jun;21(6):380-7.
Title:	Genomic and transcriptional alterations of cholangiocarcinoma.
Author:	Ito, Takeshi\|Sakurai-Yageta, Mika\|Goto, Akiteru\|Pairojkul, Chawalit\|Yongvanit, Puangrat\|Murakami, Yoshinori
PMID:	24532422

221.
Journal:	Oncologist. 2014 Mar;19(3):235-42.
Title:	New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing.
Author:	Ross, Jeffrey S\|Wang, Kai\|Gay, Laurie\|Al-Rohil, Rami\|Rand, Janne V\|Jones, David M\|Lee, Hwa J\|Sheehan, Christine E\|Otto, Geoff A\|Palmer, Gary\|Yelensky, Roman\|Lipson, Doron\|Morosini, Deborah\|Hawryluk, Matthew\|Catenacci, Daniel V T\|Miller, Vincent A\|Churi, C
PMID:	24563076

222.
Journal:	Biomark Res. 2014 Mar 17;2(1):5.
Title:	DNA methylation: potential biomarker in Hepatocellular Carcinoma.
Author:	Mah, Way-Champ\|Lee, Caroline Gl
PMID:	24635883

223.
Journal:	Hepatology. 2014 Dec;60(6):1972-82.
Title:	Genomic portrait of resectable hepatocellular carcinomas: implications of RB1 and FGF19 aberrations for patient stratification.
Author:	Ahn, Sung-Min\|Jang, Se Jin\|Shim, Ju Hyun\|Kim, Deokhoon\|Hong, Seung-Mo\|Sung, Chang Ohk\|Baek, Daehyun\|Haq, Farhan\|Ansari, Adnan Ahmad\|Lee, Sun Young\|Chun, Sung-Min\|Choi, Seongmin\|Choi, Hyun-Jeung\|Kim, Jongkyu\|Kim, Sukjun\|Hwang, Shin\|Lee, Young-Joo\|Lee, Jong
PMID:	24798001

224.
Journal:	J Hepatol. 2014 Oct;61(4):832-9.
Title:	The functional and mechanistic relatedness of EZH2 and menin in hepatocellular carcinoma.
Author:	Gao, Shu-Bin\|Xu, Bin\|Ding, Li-Hong\|Zheng, Qi-Lin\|Zhang, Li\|Zheng, Qi-Fan\|Li, Shan-Hua\|Feng, Zi-Jie\|Wei, Jie\|Yin, Zhen-Yu\|Hua, Xianxin\|Jin, Guang-Hui
PMID:	24845612

225.
Journal:	Mol Cancer Res. 2014 Oct;12(10):1388-97.
Title:	EZH2 represses target genes through H3K27-dependent and H3K27-independent mechanisms in hepatocellular carcinoma.
Author:	Gao, Shu-Bin\|Zheng, Qi-Fan\|Xu, Bin\|Pan, Chang-Bao\|Li, Kang-Li\|Zhao, Yue\|Zheng, Qi-Lin\|Lin, Xiao\|Xue, Li-Xiang\|Jin, Guang-Hui
PMID:	24916103

226.
Journal:	Oncotarget. 2014 May 30;5(10):3012-22.
Title:	Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing.
Author:	Janku, Filip\|Kaseb, Ahmed O\|Tsimberidou, Apostolia M\|Wolff, Robert A\|Kurzrock, Razelle
PMID:	24931142

227.
Journal:	Oncol Lett. 2014 Sep;8(3):963-968.
Title:	Aberrant DNA methylation in hepatocellular carcinoma tumor suppression (Review).
Author:	Dong, Youhong\|Wang, Anping
PMID:	25120642

228.
Journal:	Oncol Rep. 2014 Nov;32(5):2093-103.
Title:	DNA methyltransferases 3a and 3b are differentially expressed in the early stages of a rat liver carcinogenesis model.
Author:	Valencia Antunez, Carlos Alberto\|Taja Chayeb, Lucia\|Rodriguez-Segura, Miguel Angel\|Lopez Alvarez, Guadalupe Soledad\|Garcia-Cuellar, Claudia M\|Villa Trevino, Saul
PMID:	25190601

229.
Journal:	Int J Mol Sci. 2014 Nov 3;15(11):20004-21.
Title:	Validation of Bmi1 as a therapeutic target of hepatocellular carcinoma in mice.
Author:	Qi, Shibo\|Li, Bin\|Yang, Tan\|Liu, Yong\|Cao, Shanshan\|He, Xingxing\|Zhang, Peng\|Li, Lei\|Xu, Chuanrui
PMID:	25372945

230.
Journal:	Biochem Biophys Res Commun. 2014 Dec 12;455(3-4):262-8.
Title:	COH-203, a novel microtubule inhibitor, exhibits potent anti-tumor activity via p53-dependent senescence in hepatocellular carcinoma.
Author:	Qi, Huan\|Zuo, Dai-Ying\|Bai, Zhao-Shi\|Xu, Jing-Wen\|Li, Zeng-Qiang\|Shen, Qi-Rong\|Wang, Zhi-Wei\|Zhang, Wei-Ge\|Wu, Ying-Liang
PMID:	25449279

231.
Journal:	J Adv Res. 2014 Jan;5(1):27-40.
Title:	Methylation of multiple genes in hepatitis C virus associated hepatocellular carcinoma.
Author:	Zekri, Abdel-Rahman N\|Bahnasy, Abeer A\|Shoeab, Fatma Elzahraa M\|Mohamed, Waleed S\|El-Dahshan, Dina H\|Ali, Fahmey T\|Sabry, Gilane M\|Dasgupta, Nairajana\|Daoud, Sayed S
PMID:	25685469

232.
Journal:	Hepatol Res. 2015 Jul;45(7):782-93.
Title:	Epigenetic inactivation of transforming growth factor-beta1 target gene HEYL, a novel tumor suppressor, is involved in the P53-induced apoptotic pathway in hepatocellular carcinoma.
Author:	Kuo, Kung-Kai\|Jian, Shu-Fang\|Li, Yi-Jin\|Wan, Shi-Wei\|Weng, Ching-Chieh\|Fang, KuanTe\|Wu, Deng-Chyang\|Cheng, Kuang-Hung
PMID:	25179429

233.
Journal:	Apoptosis. 2015 Jan;20(1):75-82.
Title:	MiR-218-targeting-Bmi-1 mediates the suppressive effect of 1,6,7-trihydroxyxanthone on liver cancer cells.
Author:	Fu, Wei-Ming\|Tang, Li-Peng\|Zhu, Xiao\|Lu, Ying-Fei\|Zhang, Yan-Ling\|Lee, Wayne Yuk-Wai\|Wang, Hua\|Yu, Yang\|Liang, Wei-Cheng\|Ko, Chun-Hay\|Xu, Hong-Xi\|Kung, Hsiang-Fu\|Zhang, Jin-Fang
PMID:	25416134

234.
Journal:	Mol Med Rep. 2015 Apr;11(4):3021-6.
Title:	Celecoxib derivative OSU-03012 inhibits the proliferation and activation of hepatic stellate cells by inducing cell senescence.
Author:	Zhang, Jun\|Wang, Miao\|Zhang, Zuowei\|Luo, Zhongguang\|Liu, Fei\|Liu, Jie
PMID:	25482718

235.
Journal:	Cancer Sci. 2015 May;106(5):559-66.
Title:	Sirtuin 6 promotes transforming growth factor-beta1/H2O2/HOCl-mediated enhancement of hepatocellular carcinoma cell tumorigenicity by suppressing cellular senescence.
Author:	Feng, Xin-Xia\|Luo, Jing\|Liu, Mei\|Yan, Wei\|Zhou, Zhen-Zhen\|Xia, Yu-Jia\|Tu, Wei\|Li, Pei-Yuan\|Feng, Zuo-Hua\|Tian, De-An
PMID:	25683165

236.
Journal:	Mol Med Rep. 2015 Jul;12(1):1421-8.
Title:	Enoyl-coenzyme A hydratase short chain 1 silencing attenuates the proliferation of hepatocellular carcinoma by inhibiting epidermal growth factor signaling in vitro and in vivo.
Author:	Lin, Bi-Yun\|Xiao, Chuan-Xing\|Zhao, Wen-Xiu\|Xiao, Li\|Chen, Xu\|Li, Ping\|Wang, Xiao-Min
PMID:	25760819

237.
Journal:	Nat Genet. 2015 May;47(5):505-511.
Title:	Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets.
Author:	Schulze, Kornelius\|Imbeaud, Sandrine\|Letouze, Eric\|Alexandrov, Ludmil B\|Calderaro, Julien\|Rebouissou, Sandra\|Couchy, Gabrielle\|Meiller, Clement\|Shinde, Jayendra\|Soysouvanh, Frederic\|Calatayud, Anna-Line\|Pinyol, Roser\|Pelletier, Laura\|Balabaud, Charles\|Lau
PMID:	25822088

238.
Journal:	BMC Cancer. 2015 Mar 17;15:134.
Title:	Cyproheptadine, an antihistaminic drug, inhibits proliferation of hepatocellular carcinoma cells by blocking cell cycle progression through the activation of P38 MAP kinase.
Author:	Feng, Yu-Min\|Feng, Chin-Wen\|Chen, Syue-Yi\|Hsieh, Hsiao-Yen\|Chen, Yu-Hsin\|Hsu, Cheng-Da
PMID:	25886177

239.
Journal:	Genet Test Mol Biomarkers. 2015 Jun;19(6):295-302.
Title:	Analysis of DNA methylation in plasma for monitoring hepatocarcinogenesis.
Author:	Huang, Wenqing\|Li, Tong\|Yang, Wenli\|Chai, Xinjuan\|Chen, Kefei\|Wei, Ling\|Duan, Shuwang\|Li, Bo\|Qin, Yang
PMID:	25923138

240.
Journal:	Ann Hepatol. 2015 Jul-Aug;14(4):494-504.
Title:	DNA methylation markers and serum alpha-fetoprotein level are prognostic factors in hepatocellular carcinoma.
Author:	Lin, Jin-Ching\|Wu, Yao-Chung\|Wu, Cheng-Chung\|Shih, Pei-Yin\|Wang, Wen-Yi\|Chien, Yi-Chih
PMID:	26019036

241.
Journal:	Int J Clin Exp Med. 2015 Mar 15;8(3):4175-85. eCollection 2015.
Title:	Hepatitis B virus infection in hepatocellular carcinoma tissues upregulates expression of DNA methyltransferases.
Author:	Li, Haiping\|Yang, Fengmei\|Gao, Bo\|Yu, Zongtao\|Liu, Xiaobo\|Xie, Fei\|Zhang, Jicai
PMID:	26064328

242.
Journal:	Gastroenterology. 2015 Oct;149(5):1226-1239.e4.
Title:	Genetic Landscape and Biomarkers of Hepatocellular Carcinoma.
Author:	Zucman-Rossi, Jessica\|Villanueva, Augusto\|Nault, Jean-Charles\|Llovet, Josep M
PMID:	26099527

243.
Journal:	Mol Med Rep. 2015 Oct;12(4):5077-85.
Title:	Effects of Ras homolog gene family, member C gene silencing combined with rapamycin on hepatocellular carcinoma cell growth.
Author:	Xie, Shu-Li\|Zhu, Ming-Guang\|Chen, Guo-Fu\|Wang, Guang-Yi\|Lv, Guo-Yue
PMID:	26165487

244.
Journal:	J Toxicol Sci. 2015 Aug;40(4):501-8.
Title:	Farnesoid X receptor knockdown provides significant growth inhibition in hepatocellular carcinoma cells while it does not interfere with the proliferation of primary human hepatocyte-derived cells.
Author:	Fujino, Tomofumi\|Maruko-Ohtake, Akiko\|Ohtake, Yosuke\|Kobayashi, Tomonori\|Ando, Ken\|Takeuchi, Airi\|Ohkubo, Yasuhito\|Hayakawa, Makio
PMID:	26165647

245.
Journal:	Clin Res Hepatol Gastroenterol. 2015 Sep;39 Suppl 1:S80-5.
Title:	New molecular therapies for hepatocellular carcinoma.
Author:	Torrecilla, S\|Llovet, J M
PMID:	26206572

246.
Journal:	Exp Mol Pathol. 2015 Dec;99(3):399-408.
Title:	Hepatitis B virus X protein induces the histone H3 lysine 9 trimethylation on the promoter of p16 gene in hepatocarcinogenesis.
Author:	Wang, Di-Yi\|Zou, Li-Ping\|Liu, Xiao-Jia\|Zhu, Hong-Guang\|Zhu, Rong
PMID:	26341139

247.
Journal:	Oncotarget. 2015 Oct 20;6(32):33791-804.
Title:	HBx-related long non-coding RNA DBH-AS1 promotes cell proliferation and survival by activating MAPK signaling in hepatocellular carcinoma.
Author:	Huang, Jin-lan\|Ren, Ting-yu\|Cao, Shun-wang\|Zheng, Shi-hao\|Hu, Xiu-mei\|Hu, Yan-wei\|Lin, Li\|Chen, Jing\|Zheng, Lei\|Wang, Qian
PMID:	26393879

248.
Journal:	Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13982-7.
Title:	CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice.
Author:	Weber, Julia\|Ollinger, Rupert\|Friedrich, Mathias\|Ehmer, Ursula\|Barenboim, Maxim\|Steiger, Katja\|Heid, Irina\|Mueller, Sebastian\|Maresch, Roman\|Engleitner, Thomas\|Gross, Nina\|Geumann, Ulf\|Fu, Beiyuan\|Segler, Angela\|Yuan, Detian\|Lange, Sebastian\|Strong, Alexa
PMID:	26508638

249.
Journal:	Oncol Lett. 2015 Oct;10(4):2553-2558.
Title:	Detecting abnormal methylation of tumor suppressor genes GSTP1, P16, RIZ1, and RASSF1A in hepatocellular carcinoma and its clinical significance.
Author:	Qu, Zhen\|Jiang, Yong\|Li, Huan\|Yu, DE-Cai\|Ding, Yi-Tao
PMID:	26622888

250.
Journal:	Am J Cancer Res. 2015 Sep 15;5(10):3249-59. eCollection 2015.
Title:	Genetic polymorphisms in apoptosis-related genes and the prognosis of hepatocellular carcinoma.
Author:	Yu, Guo-Peng\|Xiao, Qian-Yi\|Shi, Zhu-Qing\|Tang, Li-Sha\|Ma, Xiao-Pin\|Zhang, Lu-Yao\|Chen, Hai-Tao\|Wang, Wen-Jia\|Zhang, Peng-Yin\|Ding, Dong-Lin\|Huang, Hui-Xing\|Saiyin, Hexige\|Chen, Tao-Yang\|Lu, Pei-Xin\|Wang, Neng-Jin\|Yu, Hong-Jie\|Sun, Jie-Lin\|Zheng, S Lilly\|X
PMID:	26693075

251.
Journal:	J Gastroenterol. 2016 May;51(5):473-86.
Title:	Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features.
Author:	Kawai-Kitahata, Fukiko\|Asahina, Yasuhiro\|Tanaka, Shinji\|Kakinuma, Sei\|Murakawa, Miyako\|Nitta, Sayuri\|Watanabe, Takako\|Otani, Satoshi\|Taniguchi, Miki\|Goto, Fumio\|Nagata, Hiroko\|Kaneko, Shun\|Tasaka-Fujita, Megumi\|Nishimura-Sakurai, Yuki\|Azuma, Seishin\|Itsui
PMID:	26553052

252.
Journal:	Hepatology. 2016 Apr;63(4):1213-26.
Title:	Aspartate beta-hydroxylase modulates cellular senescence through glycogen synthase kinase 3beta in hepatocellular carcinoma.
Author:	Iwagami, Yoshifumi\|Huang, Chiung-Kuei\|Olsen, Mark J\|Thomas, John-Michael\|Jang, Grace\|Kim, Miran\|Lin, Qiushi\|Carlson, Rolf I\|Wagner, Carl E\|Dong, Xiaoqun\|Wands, Jack R
PMID:	26683595

253.
Journal:	Int J Cancer. 2016 Jun 1;138(11):2732-44.
Title:	Hepatic miR-126 is a potential plasma biomarker for detection of hepatitis B virus infected hepatocellular carcinoma.
Author:	Ghosh, Amit\|Ghosh, Alip\|Datta, Somenath\|Dasgupta, Debanjali\|Das, Soumyajit\|Ray, Sukanta\|Gupta, Subash\|Datta, Simanti\|Chowdhury, Abhijit\|Chatterjee, Raghunath\|Mohapatra, Saroj Kant\|Banerjee, Soma
PMID:	26756996

254.
Journal:	J Gastroenterol Hepatol. 2016 Sep;31(9):1646-53.
Title:	Unique features associated with hepatic oxidative DNA damage and DNA methylation in non-alcoholic fatty liver disease.
Author:	Nishida, Naoshi\|Yada, Norihisa\|Hagiwara, Satoru\|Sakurai, Toshiharu\|Kitano, Masayuki\|Kudo, Masatoshi
PMID:	26875698

255.
Journal:	Oncol Rep. 2016 Apr;35(4):2228-36.
Title:	Genome-wide DNA methylation analysis in hepatocellular carcinoma.
Author:	Yamada, Nobuhisa\|Yasui, Kohichiroh\|Dohi, Osamu\|Gen, Yasuyuki\|Tomie, Akira\|Kitaichi, Tomoko\|Iwai, Naoto\|Mitsuyoshi, Hironori\|Sumida, Yoshio\|Moriguchi, Michihisa\|Yamaguchi, Kanji\|Nishikawa, Taichiro\|Umemura, Atsushi\|Naito, Yuji\|Tanaka, Shinji\|Arii, Shigeki\|
PMID:	26883180

256.
Journal:	Oncotarget. 2016 Apr 26;7(17):23825-36.
Title:	Two classes of intrahepatic cholangiocarcinoma defined by relative abundance of mutations and copy number alterations.
Author:	Kim, Young-Ho\|Hong, Eun-Kyung\|Kong, Sun-Young\|Han, Sung-Sik\|Kim, Seoung-Hoon\|Rhee, Je-Keun\|Hwang, Soo-Kyung\|Park, Sang-Jae\|Kim, Tae-Min
PMID:	27009864

257.
Journal:	Gene. 2016 Jul 10;585(2):241-6.
Title:	Anti-tumor effects of bemiparin in HepG2 and MIA PaCa-2 cells.
Author:	Alur, Ihsan\|Dodurga, Yavuz\|Secme, Mucahit\|Elmas, Levent\|Bagci, Gulseren\|Goksin, Ibrahim\|Avci, Cigir Biray
PMID:	27048831

258.
Journal:	Nat Genet. 2016 May;48(5):500-9.
Title:	Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer.
Author:	Fujimoto, Akihiro\|Furuta, Mayuko\|Totoki, Yasushi\|Tsunoda, Tatsuhiko\|Kato, Mamoru\|Shiraishi, Yuichi\|Tanaka, Hiroko\|Taniguchi, Hiroaki\|Kawakami, Yoshiiku\|Ueno, Masaki\|Gotoh, Kunihito\|Ariizumi, Shun-Ichi\|Wardell, Christopher P\|Hayami, Shinya\|Nakamura, Toru\|A
PMID:	27064257

259.
Journal:	Oncol Res. 2016;23(5):237-48.
Title:	Raltitrexed Inhibits HepG2 Cell Proliferation via G0/G1 Cell Cycle Arrest.
Author:	Zhao, Hongwei\|Zhang, Yubao\|Sun, Jianmin\|Zhan, Chao\|Zhao, Liang
PMID:	27098147

260.
Journal:	Epigenetics. 2016 Aug 11:1-12.
Title:	Efficacy and epigenetic interactions of novel DNA hypomethylating agent guadecitabine (SGI-110) in preclinical models of hepatocellular carcinoma.
Author:	Jueliger, Simone\|Lyons, John\|Cannito, Sara\|Pata, Illar\|Pata, Pille\|Shkolnaya, Marianna\|Lo Re, Oriana\|Peyrou, Marion\|Villarroya, Francesc\|Pazienza, Valerio\|Rappa, Francesca\|Cappello, Francesco\|Azab, Mohammad\|Taverna, Pietro\|Vinciguerra, Manlio
PMID:	27646854

261.
Journal:	Int J Oncol. 2016 Nov;49(5):2046-2054.
Title:	The herbal medicine Cyperus amuricus inhibits proliferation of human hepatocellular carcinoma Hep3B cells by inducing apoptosis and arrest at the G0/G1 cell cycle phase.
Author:	Pham, Hai Ha Thi\|Seong, Yeong-Ae\|Oh, Chul-Woong\|Kim, Gun-Do
PMID:	27667556

262.
Journal:	Oncotarget. 2016 Nov 1;7(44):72131-72147.
Title:	PRMT5 competitively binds to CDK4 to promote G1-S transition upon glucose induction in hepatocellular carcinoma.
Author:	Yang, Hao\|Zhao, Xiaoping\|Zhao, Li\|Liu, Liu\|Li, Jiajin\|Jia, Wenzhi\|Liu, Jianjun\|Huang, Gang
PMID:	27708221

263.
Journal:	Genes Dev. 2016 Oct 1;30(19):2187-2198.
Title:	SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer.
Author:	Tordella, Luca\|Khan, Sadaf\|Hohmeyer, Anja\|Banito, Ana\|Klotz, Sabrina\|Raguz, Selina\|Martin, Nadine\|Dhamarlingam, Gopuraja\|Carroll, Thomas\|Gonzalez Meljem, Jose Mario\|Deswal, Sumit\|Martinez-Barbera, Juan Pedro\|Garcia-Escudero, Ramon\|Zuber, Johannes\|Zender,
PMID:	27737960

264.
Journal:	PLoS One. 2016 Nov 8;11(11):e0165835.
Title:	SIRT6 Depletion Suppresses Tumor Growth by Promoting Cellular Senescence Induced by DNA Damage in HCC.
Author:	Lee, Namgyu\|Ryu, Hye Guk\|Kwon, Jung-Hee\|Kim, Dae-Kyum\|Kim, Sae Rom\|Wang, Hee Jung\|Kim, Kyong-Tai\|Choi, Kwan Yong
PMID:	27824900

265.
Journal:	Oncotarget. 2016 Dec 6;7(49):81255-81267.
Title:	Meta-analysis of DNA methylation biomarkers in hepatocellular carcinoma.
Author:	Zhang, Cheng\|Li, Jinyun\|Huang, Tao\|Duan, Shiwei\|Dai, Dongjun\|Jiang, Danjie\|Sui, Xinbing\|Li, Da\|Chen, Yidan\|Ding, Fei\|Huang, Changxin\|Chen, Gongying\|Wang, Kaifeng
PMID:	27835605

266.
Journal:	BMC Cancer. 2016 Nov 18;16(1):903.
Title:	Keratin 19 as a key molecule in progression of human hepatocellular carcinomas through invasion and angiogenesis.
Author:	Takano, Masato\|Shimada, Keiji\|Fujii, Tomomi\|Morita, Kohei\|Takeda, Maiko\|Nakajima, Yoshiyuki\|Nonomura, Akitaka\|Konishi, Noboru\|Obayashi, Chiho
PMID:	27863477

267.
Journal:	Cell Rep. 2016 Nov 22;17(9):2234-2246.
Title:	Tailored Tumor Immunogenicity Reveals Regulation of CD4 and CD8 T Cell Responses against Cancer.
Author:	Knocke, Sarah\|Fleischmann-Mundt, Bettina\|Saborowski, Michael\|Manns, Michael P\|Kuhnel, Florian\|Wirth, Thomas C\|Woller, Norman
PMID:	27880900

268.
Journal:	Hepatol Int. 2017 Jan;11(1):45-53.
Title:	Epigenetic mechanisms regulating the development of hepatocellular carcinoma and their promise for therapeutics.
Author:	Khan, Faisal Saeed\|Ali, Ijaz\|Afridi, Ume Kalsoom\|Ishtiaq, Muhammad\|Mehmood, Rashid
PMID:	27271356

269.
Journal:	Oncogene. 2017 Jun 15;36(24):3464-3476.
Title:	The novel MKL target gene myoferlin modulates expansion and senescence of hepatocellular carcinoma.
Author:	Hermanns, C\|Hampl, V\|Holzer, K\|Aigner, A\|Penkava, J\|Frank, N\|Martin, D E\|Maier, K C\|Waldburger, N\|Roessler, S\|Goppelt-Struebe, M\|Akrap, I\|Thavamani, A\|Singer, S\|Nordheim, A\|Gudermann, T\|Muehlich, S
PMID:	28114277

270.
Journal:	Radiology. 2017 Jun;283(3):702-710.
Title:	Ischemia Induces Quiescence and Autophagy Dependence in Hepatocellular Carcinoma.
Author:	Gade, Terence P F\|Tucker, Elizabeth\|Nakazawa, Michael S\|Hunt, Stephen J\|Wong, Waihay\|Krock, Bryan\|Weber, Charles N\|Nadolski, Gregory J\|Clark, Timothy W I\|Soulen, Michael C\|Furth, Emma E\|Winkler, Jeffrey D\|Amaravadi, Ravi K\|Simon, M Celeste
PMID:	28253108

271.
Journal:	PeerJ. 2017 Mar 14;5:e3089.
Title:	From big data to diagnosis and prognosis: gene expression signatures in liver hepatocellular carcinoma.
Author:	Yang, Hong\|Zhang, Xin\|Cai, Xiao-Yong\|Wen, Dong-Yue\|Ye, Zhi-Hua\|Liang, Liang\|Zhang, Lu\|Wang, Han-Lin\|Chen, Gang\|Feng, Zhen-Bo
PMID:	28316892

272.
Journal:	Eur Rev Med Pharmacol Sci. 2017 Mar;21(6):1248-1253.
Title:	Facilitation of liver cancer SMCC7721 cell aging by sirtuin 4 via inhibiting JAK2/STAT3 signal pathway.
Author:	Xia, X-H\|Xiao, C-J\|Shan, H
PMID:	28387906

273.
Journal:	Lipids Health Dis. 2017 Apr 13;16(1):76.
Title:	E167K polymorphism of TM6SF2 gene affects cell cycle of hepatocellular carcinoma cell HEPA 1-6.
Author:	Du, Shuixian\|Lu, Linlin\|Miao, Yingxia\|Jin, Wenwen\|Li, Changfei\|Xin, Yongning\|Xuan, Shiying
PMID:	28407767

274.
Journal:	PLoS One. 2017 Aug 18;12(8):e0182705.
Title:	Ribosomopathy-like properties of murine and human cancers.
Author:	Kulkarni, Sucheta\|Dolezal, James M\|Wang, Huabo\|Jackson, Laura\|Lu, Jie\|Frodey, Brian P\|Dosunmu-Ogunbi, Atinuke\|Li, Youjun\|Fromherz, Marc\|Kang, Audry\|Santana-Santos, Lucas\|Benos, Panayiotis V\|Prochownik, Edward V
PMID:	28820908

275.
Journal:	Mol Cancer. 2017 Aug 30;16(1):149.
Title:	The biology of Hepatocellular carcinoma: implications for genomic and immune therapies.
Author:	Khemlina, Galina\|Ikeda, Sadakatsu\|Kurzrock, Razelle
PMID:	28854942

276.
Journal:	Eur J Pharmacol. 2017 Nov 15;815:173-180.
Title:	20(S)-Ginsenoside Rh2 suppresses proliferation and migration of hepatocellular carcinoma cells by targeting EZH2 to regulate CDKN2A-2B gene cluster transcription.
Author:	Li, Qi\|Li, Bai\|Dong, Chengya\|Wang, Yajie\|Li, Qi
PMID:	28928088

277.
Journal:	Medicine (Baltimore). 2017 Sep;96(38):e8106.
Title:	p16 Methylation was associated with the development, age, hepatic viruses infection of hepatocellular carcinoma, and p16 expression had a poor survival: A systematic meta-analysis (PRISMA).
Author:	Lv, Xueyou\|Ye, Guoliang\|Zhang, Xinjun\|Huang, Tao
PMID:	28930859

278.
Journal:	Carcinogenesis. 2017 Oct 1;38(10):1021-1028.
Title:	Plasma DNA methylation marker and hepatocellular carcinoma risk prediction model for the general population.
Author:	Wu, Hui-Chen\|Yang, Hwai-I\|Wang, Qiao\|Chen, Chien-Jen\|Santella, Regina M
PMID:	28981677

279.
Journal:	Medicine (Baltimore). 2017 Oct;96(41):e8279.
Title:	Methylation analysis of p16, SLIT2, SCARA5, and Runx3 genes in hepatocellular carcinoma.
Author:	Sun, Gaofeng\|Zhang, Chen\|Feng, Min\|Liu, Wensheng\|Xie, Huifang\|Qin, Qin\|Zhao, E\|Wan, Li
PMID:	29019900

280.
Journal:	Carcinogenesis. 2018 Mar 8;39(3):318-326.
Title:	p19Arf inhibits aggressive progression of H-ras-driven hepatocellular carcinoma.
Author:	Kopanja, Dragana\|Huang, Shuo\|Al Raheed, Mohamed Rizwan Haroon\|Guzman, Grace\|Raychaudhuri, Pradip
PMID:	29228217

281.
Journal:	Future Oncol. 2018 Mar;14(6):553-566.
Title:	Novel targeted therapy strategies for biliary tract cancers and hepatocellular carcinoma.
Author:	DeLeon, Thomas T\|Ahn, Daniel H\|Bogenberger, James M\|Anastasiadis, Panos Z\|Arora, Mansi\|Ramanathan, Ramesh K\|Aqel, Bashar A\|Vasmatzis, George\|Truty, Mark J\|Oklu, Rahmi\|Bekaii-Saab, Tanios S\|Borad, Mitesh J
PMID:	29460642

282.
Journal:	Oncologist. 2018 May;23(5):586-593.
Title:	Next-Generation Sequencing of Circulating Tumor DNA Reveals Frequent Alterations in Advanced Hepatocellular Carcinoma.
Author:	Ikeda, Sadakatsu\|Tsigelny, Igor F\|Skjevik, Age A\|Kono, Yuko\|Mendler, Michel\|Kuo, Alexander\|Sicklick, Jason K\|Heestand, Gregory\|Banks, Kimberly C\|Talasaz, AmirAli\|Lanman, Richard B\|Lippman, Scott\|Kurzrock, Razelle
PMID:	29487225

283.
Journal:	Cell Death Dis. 2018 May 1;9(5):443.
Title:	A Trib2-p38 axis controls myeloid leukaemia cell cycle and stress response signalling.
Author:	Salome, Mara\|Magee, Aoife\|Yalla, Krisha\|Chaudhury, Shahzya\|Sarrou, Evgenia\|Carmody, Ruaidhri J\|Keeshan, Karen
PMID:	29670085

284.
Journal:	Cell Death Dis. 2018 May 1;9(5):534.
Title:	Reducing protein regulator of cytokinesis 1 as a prospective therapy for hepatocellular carcinoma.
Author:	Liu, Xinran\|Li, Yangkai\|Meng, Lijing\|Liu, Xin-Yuan\|Peng, Anlin\|Chen, Yuchen\|Liu, Chengyu\|Chen, Hong\|Sun, Sheng\|Miao, Xiaoping\|Zhang, Yu\|Zheng, Ling\|Huang, Kun
PMID:	29748662

285.
Journal:	Biosci Rep. 2018 Jul 31;38(4). pii: BSR20180365.
Title:	Association between long non-coding RNA polymorphisms and cancer risk: a meta-analysis.
Author:	Huang, Xin\|Zhang, Weiyue\|Shao, Zengwu
PMID:	29802154

286.
Journal:	J Cancer. 2018 Jun 4;9(12):2203-2210.
Title:	Predicting hepatocellular carcinoma development for cirrhosis patients via methylation detection of heparocarcinogenesis-related genes.
Author:	Huang, Yuan\|Wei, Ling\|Zhao, Rong-Ce\|Liang, Wei-Bo\|Zhang, Jing\|Ding, Xue-Qin\|Li, Zhi-Long\|Sun, Cheng-Jun\|Li, Bo\|Liu, Qiu-Ying\|He, Jing-Yang\|Yu, Xiao-Qin\|Gao, Bo\|Chen, Ming-Mei\|Sun, Ai-Min\|Qin, Yang
PMID:	29937940

287.
Journal:	Hum Pathol. 2018 Jun 24. pii: S0046-8177(18)30240-5.
Title:	Genomic structures of dysplastic nodule and concurrent hepatocellular carcinoma.
Author:	Lee, Minho\|Kim, Kyung\|Kim, Shinn Young\|Jung, Seung-Hyun\|Yoon, Jonghwan\|Kim, Min Sung\|Park, Hyeon-Chun\|Jung, Eun Sun\|Chung, Yeun-Jun\|Lee, Sug Hyung
PMID:	29949741

288.
Journal:	Nature. 2018 Aug;560(7717):253-257.
Title:	Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth.
Author:	Baell, Jonathan B\|Leaver, David J\|Hermans, Stefan J\|Kelly, Gemma L\|Brennan, Margs S\|Downer, Natalie L\|Nguyen, Nghi\|Wichmann, Johannes\|McRae, Helen M\|Yang, Yuqing\|Cleary, Ben\|Lagiakos, H Rachel\|Mieruszynski, Stephen\|Pacini, Guido\|Vanyai, Hannah K\|Bergamasc
PMID:	30069049

289.
Journal:	Toxicol Rep. 2018 Jul 25;5:777-784.
Title:	Aflatoxin B1 residues in human livers and their relationship with markers of hepatic carcinogenesis in Sao Paulo, Brazil.
Author:	Ramalho, Leandra N Z\|Porta, Livia D\|Rosim, Roice E\|Petta, Tania\|Augusto, Marlei J\|Silva, Deisy M\|Ramalho, Fernando S\|Oliveira, Carlos A F
PMID:	30101081

290.
Journal:	Clin Res Hepatol Gastroenterol. 2018 Aug 21. pii: S2210-7401(17)30178-X.
Title:	CDKN2A promoter methylation and hepatocellular carcinoma risk: A meta-analysis.
Author:	Zhou, Ye\|Wang, Xue-Bin\|Qiu, Xue-Ping\|Shuai Zhang\|Wang, Chen\|Zheng, Fang
PMID:	30143452

291.
Journal:	Cell Death Dis. 2018 Sep 6;9(9):912.
Title:	Differentiation therapy and the mechanisms that terminate cancer cell proliferation without harming normal cells.
Author:	Enane, Francis O\|Saunthararajah, Yogen\|Korc, Murray
PMID:	30190481

292.
Journal:	Cancer Sci. 2018 Sep 6.
Title:	Inhibition of KIF20B sensitizes hepatocellular carcinoma cell to microtubule-targeting agents by blocking cytokinesis.
Author:	Liu, Xinran\|Li, Yangkai\|Zhang, Xia\|Liu, Xin-Yuan\|Peng, Anlin\|Chen, Yuchen\|Meng, Lijing\|Chen, Hong\|Zhang, Yu\|Miao, Xiaoping\|Zheng, Ling\|Huang, Kun
PMID:	30191636

293.
Journal:	J Exp Clin Cancer Res. 2018 Sep 20;37(1):233.
Title:	Integrated genomic analyses in PDX model reveal a cyclin-dependent kinase inhibitor Palbociclib as a novel candidate drug for nasopharyngeal carcinoma.
Author:	Hsu, Cheng-Lung\|Lui, Kar-Wai\|Chi, Lang-Ming\|Kuo, Yung-Chia\|Chao, Yin-Kai\|Yeh, Chun-Nan\|Lee, Li-Yu\|Huang, Yenlin\|Lin, Tung-Liang\|Huang, Mei-Yuan\|Lai, Yi-Ru\|Yeh, Yuan-Ming\|Fan, Hsien-Chi\|Lin, An-Chi\|Lu, Yen-Jung\|Hsieh, Chia-Hsun\|Chang, Kai-Ping\|Tsang, Ngan-
PMID:	30236142

294.
Journal:	Clin Cancer Res. 2018 Sep 21. pii: 1078-0432.CCR-18-0088.
Title:	Multi-modal meta-analysis of 1494 hepatocellular carcinoma samples reveals significant impact of consensus driver genes on phenotypes.
Author:	Chaudhary, Kumardeep\|Poirion, Olivier B\|Lu, Liangqun\|Huang, Sijia\|Ching, Travers\|Garmire, Lana X
PMID:	30242023

295.
Journal:	BMC Cancer. 2018 Sep 24;18(1):919.
Title:	Knockdown long non-coding RNA ANRIL inhibits proliferation, migration and invasion of HepG2 cells by down-regulation of miR-191.
Author:	Huang, Deyu\|Bi, Chunhua\|Zhao, Qingxi\|Ding, Xueli\|Bian, Cheng\|Wang, Hui\|Wang, Ting\|Liu, Hua
PMID:	30249208

296.
Journal:	Biomed Res Int. 2018 Sep 30;2018:7897346.
Title:	Upregulation of BUB1B, CCNB1, CDC7, CDC20, and MCM3 in Tumor Tissues Predicted Worse Overall Survival and Disease-Free Survival in Hepatocellular Carcinoma Patients.
Author:	Zhuang, Liping\|Yang, Zongguo\|Meng, Zhiqiang
PMID:	30363964