Primary Site >> Colorectal Cancer

Gene >> CDKN2A

Journal: Cancer Res. 1995 Oct 15;55(20):4525-30.
Title: Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers.
Author: Herman, J G|Merlo, A|Mao, L|Lapidus, R G|Issa, J P|Davidson, N E|Sidransky, D|Baylin, S B
PMID: 7553621
Journal: Cancer Res. 1995 Oct 15;55(20):4531-5.
Title: Methylation of the 5' CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing.
Author: Gonzalez-Zulueta, M|Bender, C M|Yang, A S|Nguyen, T|Beart, R W|Van Tornout, J M|Jones, P A
PMID: 7553622
Journal: Toxicol Lett. 1995 Dec;82-83:1-7.
Title: 1995 Deichmann Lecture--p53 tumor suppressor gene: at the crossroads of molecular carcinogenesis, molecular epidemiology and cancer risk assessment.
Author: Harris, C C
PMID: 8597035
Journal: Cancer Res. 1996 Feb 15;56(4):722-7.
Title: Hypermethylation-associated inactivation indicates a tumor suppressor role for p15INK4B.
Author: Herman, J G|Jen, J|Merlo, A|Baylin, S B
PMID: 8631003
Journal: Mol Carcinog. 1996 May;16(1):53-60.
Title: Suppression of growth in vitro and tumorigenicity in vivo of human carcinoma cell lines by transfected p16INK4.
Author: Spillare, E A|Okamoto, A|Hagiwara, K|Demetrick, D J|Serrano, M|Beach, D|Harris, C C
PMID: 8634094
Journal: Biochem Biophys Res Commun. 1996 Sep 24;226(3):791-5.
Title: Activation but not inactivation of the MTS1 gene is associated with primary colorectal carcinomas.
Author: Ohhara, M|Esumi, M|Kurosu, Y
PMID: 8831691
Journal: Cancer Res. 1996 Oct 15;56(20):4662-5.
Title: Microsatellite instability-associated mutations associate preferentially with the intestinal type of primary gastric carcinomas in a high-risk population.
Author: Chung, Y J|Song, J M|Lee, J Y|Jung, Y T|Seo, E J|Choi, S W|Rhyu, M G
PMID: 8840981
Journal: Recent Results Cancer Res. 1996;142:1-8.
Title: The molecular biology of esophageal carcinoma.
Author: Meltzer, S J
PMID: 8893331
Journal: Nihon Rinsho. 1996 Apr;54(4):965-71.
Title: [RB gene expression in gastrointestinal tract].
Author: Monden, T|Yamamoto, H|Ikeda, K|Izawa, H|Tsujie, M|Ohnishi, T|Miyoshi, Y|Sekimoto, M|Tomita, N|Monden, M
PMID: 8920658
Journal: Nihon Rinsho. 1996 Apr;54(4):1054-9.
Title: [Cyclin D, CDK4 and p16 expression in colorectal cancer].
Author: Ikeda, K|Monden, T|Tsujie, M|Izawa, H|Yamamoto, H|Ohnishi, T|Ohue, M|Sekimoto, M|Tomita, N|Monden, M
PMID: 8920673
Journal: Cancer Res. 1996 Dec 15;56(24):5713-9.
Title: Orthotopic xenografts of human pancreatic carcinomas acquire genetic aberrations during dissemination in nude mice.
Author: Reyes, G|Villanueva, A|Garcia, C|Sancho, F J|Piulats, J|Lluis, F|Capella, G
PMID: 8971180
Journal: Am J Surg. 1997 Jan;173(1):37-41; discussion 42-3.
Title: Advances in molecular genetics.
Author: Lairmore, T C|Norton, J A
PMID: 9046882
Journal: Cancer Res. 1997 Aug 15;57(16):3370-4.
Title: Association between CpG island methylation and microsatellite instability in colorectal cancer.
Author: Ahuja, N|Mohan, A L|Li, Q|Stolker, J M|Herman, J G|Hamilton, S R|Baylin, S B|Issa, J P
PMID: 9269998
Journal: Jpn J Cancer Res. 1997 Sep;88(9):855-60.
Title: Expressions of cell cycle regulators in human colorectal cancer cell lines.
Author: Tominaga, O|Nita, M E|Nagawa, H|Fujii, S|Tsuruo, T|Muto, T
PMID: 9369933
Journal: J Cell Biochem Suppl. 1997;28-29:64-73.
Title: Genetic markers for early detection of lung cancer and outcome measures for response to chemoprevention.
Author: Wiest, J S|Franklin, W A|Drabkin, H|Gemmill, R|Sidransky, D|Anderson, M W
PMID: 9589350
Journal: Semin Surg Oncol. 1998 Jan-Feb;14(1):3-12.
Title: Molecular changes during the genesis of human gliomas.
Author: Sehgal, A
PMID: 9407626
Journal: Cancer Res. 1998 Jan 1;58(1):109-13.
Title: Novel mutations in the p16/CDKN2A binding region of the cyclin-dependent kinase-4 gene.
Author: Tsao, H|Benoit, E|Sober, A J|Thiele, C|Haluska, F G
PMID: 9426066
Journal: Mol Carcinog. 1998 Jan;21(1):37-49.
Title: Decreased expression of the adenomatous polyposis coli (Apc) and mutated in colorectal cancer (Mcc) genes in mouse lung neoplasia.
Author: Oreffo, V I|Robinson, S|You, M|Wu, M C|Malkinson, A M
PMID: 9473770
Journal: Cancer Res. 1998 Feb 15;58(4):591-3.
Title: Hypermethylation can selectively silence individual p16ink4A alleles in neoplasia.
Author: Myohanen, S K|Baylin, S B|Herman, J G
PMID: 9485004
Journal: J Pathol. 1998 Feb;184(2):148-52.
Title: A comparison of the genetic pathways involved in the pathogenesis of three types of colorectal cancer.
Author: Tomlinson, I|Ilyas, M|Johnson, V|Davies, A|Clark, G|Talbot, I|Bodmer, W
PMID: 9602705
Journal: Jpn J Clin Oncol. 1998 Mar;28(3):192-5.
Title: Identification and characterization of families with aggregation of lung cancer.
Author: Tomizawa, Y|Adachi, J|Kohno, T|Yamaguchi, N|Saito, R|Yokota, J
PMID: 9614442
Journal: Cancer Res. 1998 Jun 1;58(11):2339-42.
Title: Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor suppressor gene.
Author: Su, G H|Hilgers, W|Shekher, M C|Tang, D J|Yeo, C J|Hruban, R H|Kern, S E
PMID: 9622070
Journal: Cancer Res. 1998 Sep 1;58(17):3942-5.
Title: Hypermethylation of the p16INK4a promoter in colectomy specimens of patients with long-standing and extensive ulcerative colitis.
Author: Hsieh, C J|Klump, B|Holzmann, K|Borchard, F|Gregor, M|Porschen, R
PMID: 9731506
Journal: Genomics. 1998 Oct 15;53(2):129-36.
Title: At least four loci and gender are associated with susceptibility to the chemical induction of lung adenomas in A/J x BALB/c mice.
Author: Festing, M F|Lin, L|Devereux, T R|Gao, F|Yang, A|Anna, C H|White, C M|Malkinson, A M|You, M
PMID: 9790761
Journal: Clin Chem Lab Med. 1998 Aug;36(8):645-8.
Title: Screening for tumour suppressor p16(CDKN2A) germline mutations in Israeli melanoma families.
Author: Yakobson, E A|Zlotogorski, A|Shafir, R|Cohen, M|Icekson, M|Landau, M|Brenner, S|Usher, S|Peretz, H
PMID: 9806478
Journal: Mol Cell Biochem. 1998 Nov;188(1-2):21-30.
Title: Sodium butyrate induces retinoblastoma protein dephosphorylation, p16 expression and growth arrest of colon cancer cells.
Author: Schwartz, B|Avivi-Green, C|Polak-Charcon, S
PMID: 9823007
Journal: Cancer Res. 1998 Dec 1;58(23):5489-94.
Title: Aging and DNA methylation in colorectal mucosa and cancer.
Author: Ahuja, N|Li, Q|Mohan, A L|Baylin, S B|Issa, J P
PMID: 9850084
Journal: Arch Dermatol Res. 1999 Jan;291(1):1-5.
Title: Assessment of microsatellite instability and loss of heterozygosity in sporadic keratoacanthomas.
Author: Langenbach, N|Kroiss, M M|Ruschoff, J|Schlegel, J|Landthaler, M|Stolz, W
PMID: 10025721
Journal: Mol Cell Biol. 1999 May;19(5):3916-28.
Title: Induction of p21(WAF1/CIP1) and inhibition of Cdk2 mediated by the tumor suppressor p16(INK4a).
Author: Mitra, J|Dai, C Y|Somasundaram, K|El-Deiry, W S|Satyamoorthy, K|Herlyn, M|Enders, G H
PMID: 10207115
Journal: Gastroenterology. 1999 May;116(5):1063-71.
Title: Association of K-ras mutations with p16 methylation in human colon cancer.
Author: Guan, R J|Fu, Y|Holt, P R|Pardee, A B
PMID: 10220498
Journal: Cancer Res. 1999 May 15;59(10):2302-6.
Title: CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression.
Author: Eads, C A|Danenberg, K D|Kawakami, K|Saltz, L B|Danenberg, P V|Laird, P W
PMID: 10344733
Journal: Cancer Res. 1999 May 15;59(10):2307-12.
Title: Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification.
Author: Toyota, M|Ho, C|Ahuja, N|Jair, K W|Li, Q|Ohe-Toyota, M|Baylin, S B|Issa, J P
PMID: 10344734
Journal: Int J Cancer. 1999 Jun 11;81(6):902-10.
Title: Establishment and characterization of 12 human colorectal-carcinoma cell lines.
Author: Oh, J H|Ku, J L|Yoon, K A|Kwon, H J|Kim, W H|Park, H S|Yeo, K S|Song, S Y|Chung, J K|Park, J G
PMID: 10362137
Journal: Cancer Epidemiol Biomarkers Prev. 1999 Jun;8(6):501-6.
Title: Aberrant methylation of p16INK4a in anatomic and gender-specific subtypes of sporadic colorectal cancer.
Author: Wiencke, J K|Zheng, S|Lafuente, A|Lafuente, M J|Grudzen, C|Wrensch, M R|Miike, R|Ballesta, A|Trias, M
PMID: 10385139
Journal: Proc Natl Acad Sci U S A. 1999 Jul 20;96(15):8681-6.
Title: CpG island methylator phenotype in colorectal cancer.
Author: Toyota, M|Ahuja, N|Ohe-Toyota, M|Herman, J G|Baylin, S B|Issa, J P
PMID: 10411935
Journal: Hautarzt. 1999 Jun;50(6):398-405.
Title: [Pathogenesis of malignant melanoma. Molecular biology aspect].
Author: Waldmann, V|Bock, M|Jackel, A|Deichmann, M|Dockendorff, K|Naher, H
PMID: 10427507
Journal: Oncology. 1999;57(2):149-56.
Title: Hypermethylation of the p16 gene in sporadic T3N0M0 stage colorectal cancers: association with DNA replication error and shorter survival.
Author: Liang, J T|Chang, K J|Chen, J C|Lee, C C|Cheng, Y M|Hsu, H C|Wu, M S|Wang, S M|Lin, J T|Cheng, A L
PMID: 10461063
Journal: Anticancer Drugs. 1999 Jun;10(5):471-6.
Title: DNA methylation of retinoic acid receptor beta in breast cancer and possible therapeutic role of 5-aza-2'-deoxycytidine.
Author: Bovenzi, V|Le, N L|Cote, S|Sinnett, D|Momparler, L F|Momparler, R L
PMID: 10477167
Journal: Int J Cancer. 1999 Oct 29;83(3):309-13.
Title: Distinct methylation pattern and microsatellite instability in sporadic gastric cancer.
Author: Suzuki, H|Itoh, F|Toyota, M|Kikuchi, T|Kakiuchi, H|Hinoda, Y|Imai, K
PMID: 10495421
Journal: Clin Cancer Res. 1999 Sep;5(9):2450-4.
Title: Molecular detection of neoplastic cells in lymph nodes of metastatic colorectal cancer patients predicts recurrence.
Author: Sanchez-Cespedes, M|Esteller, M|Hibi, K|Cope, F O|Westra, W H|Piantadosi, S|Herman, J G|Jen, J|Sidransky, D
PMID: 10499618
Journal: Cytogenet Cell Genet. 1999;86(2):142-7.
Title: Genome-wide allelotyping indicates increased loss of heterozygosity on 9p and 14q in early age of onset colorectal cancer.
Author: Weber, T K|Conroy, J|Keitz, B|Rodriguez-Bigas, M|Petrelli, N J|Stoler, D L|Anderson, G R|Shows, T B|Nowak, N J
PMID: 10545706
Journal: Cancer Res. 1999 Nov 1;59(21):5438-42.
Title: Aberrant methylation in gastric cancer associated with the CpG island methylator phenotype.
Author: Toyota, M|Ahuja, N|Suzuki, H|Itoh, F|Ohe-Toyota, M|Imai, K|Baylin, S B|Issa, J P
PMID: 10554013
Journal: Cancer Epidemiol Biomarkers Prev. 1999 Dec;8(12):1101-5.
Title: Abnormalities in the expression of cell cycle-related proteins in tumors of the small bowel.
Author: Arber, N|Hibshoosh, H|Yasui, W|Neugut, A I|Hibshoosh, A|Yao, Y|Sgambato, A|Yamamoto, H|Shapira, I|Rosenman, D|Fabian, I|Weinstein, I B|Tahara, E|Holt, P R
PMID: 10613343
Journal: Neoplasia. 1999 Dec;1(6):544-56.
Title: p53-independent inhibition of proliferation and p21(WAF1/Cip1)-modulated induction of cell death by the antioxidants N-acetylcysteine and vitamin E.
Author: Nargi, J L|Ratan, R R|Griffin, D E
PMID: 10935502
Journal: World J Gastroenterol. 1999 Oct;5(5):451-454.
Title: Methylation status of p16 gene in colorectal carcinoma and normal colonic mucosa.
Author: Zhang, Jing|Lai, Mao-De|Chen, Jian
PMID: 11819489
Journal: Zhonghua Wai Ke Za Zhi. 1999 Aug;37(8):494-6.
Title: [The expression of MTS1 gene product in transitional mucosa adjacent to rectal carcinomas and its clinical significance].
Author: Su, Q|Liu, E|Chen, C|Feng, Y|Wang, W|Wang, Z
PMID: 11829899
Journal: Zhonghua Bing Li Xue Za Zhi. 1999 Dec;28(6):418-21.
Title: [Microsatellite alterations on chromosome 9p21-22 in sporadic colorectal cancer].
Author: Zhang, Y|Lai, M
PMID: 11869554
Journal: Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):710-5.
Title: Distinct genetic profiles in colorectal tumors with or without the CpG island methylator phenotype.
Author: Toyota, M|Ohe-Toyota, M|Ahuja, N|Issa, J P
PMID: 10639144
Journal: Cancer Res. 2000 Jan 1;60(1):129-33.
Title: Hypermethylation-associated inactivation of p14(ARF) is independent of p16(INK4a) methylation and p53 mutational status.
Author: Esteller, M|Tortola, S|Toyota, M|Capella, G|Peinado, M A|Baylin, S B|Herman, J G
PMID: 10646864
Journal: Oncogene. 2000 Feb 17;19(7):943-52.
Title: DNA methylator and mismatch repair phenotypes are not mutually exclusive in colorectal cancer cell lines.
Author: Pao, M M|Liang, G|Tsai, Y C|Xiong, Z|Laird, P W|Jones, P A
PMID: 10702803
Journal: J Natl Cancer Inst. 2000 Apr 19;92(8):636-41.
Title: Adenovirus-mediated p14(ARF) gene transfer in human mesothelioma cells.
Author: Yang, C T|You, L|Yeh, C C|Chang, J W|Zhang, F|McCormick, F|Jablons, D M
PMID: 10772681
Journal: Nature. 2000 Apr 27;404(6781):1003-7.
Title: CpG methylation is maintained in human cancer cells lacking DNMT1.
Author: Rhee, I|Jair, K W|Yen, R W|Lengauer, C|Herman, J G|Kinzler, K W|Vogelstein, B|Baylin, S B|Schuebel, K E
PMID: 10801130
Journal: Cancer Res. 2000 May 1;60(9):2368-71.
Title: Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis.
Author: Esteller, M|Toyota, M|Sanchez-Cespedes, M|Capella, G|Peinado, M A|Watkins, D N|Issa, J P|Sidransky, D|Baylin, S B|Herman, J G
PMID: 10811111
Journal: Mol Carcinog. 2000 Jul;28(3):139-47.
Title: Differential expression of p16(INK4a) in azoxymethane-induced mouse colon tumorigenesis.
Author: Wang, Q S|Papanikolaou, A|Nambiar, P R|Rosenberg, D W
PMID: 10942530
Journal: Histol Histopathol. 2000 Jul;15(3):835-42.
Title: Aging, methylation and cancer.
Author: Ahuja, N|Issa, J P
PMID: 10963127
Journal: Cancer J. 2000 Jul-Aug;6(4):234-42.
Title: Cell cycle regulation of the G0/G1 transition in 5-fluorouracil-sensitive and -resistant human colon cancer cell lines.
Author: McGinn, C J|Pestalozzi, B C|Drake, J C|Glennon, M C|Kunugi, K|Otterson, G|Allegra, C J|Johnston, P G|Kinsella, T J
PMID: 11038143
Journal: Gastroenterology. 2000 Oct;119(4):929-42.
Title: p16(INK4a) expression begins early in human colon neoplasia and correlates inversely with markers of cell proliferation.
Author: Dai, C Y|Furth, E E|Mick, R|Koh, J|Takayama, T|Niitsu, Y|Enders, G H
PMID: 11040180
Journal: Carcinogenesis. 2000 Nov;21(11):2057-64.
Title: Correlations of partial and extensive methylation at the p14(ARF) locus with reduced mRNA expression in colorectal cancer cell lines and clinicopathological features in primary tumors.
Author: Zheng, S|Chen, P|McMillan, A|Lafuente, A|Lafuente, M J|Ballesta, A|Trias, M|Wiencke, J K
PMID: 11062168
Journal: Int J Cancer. 2000 Dec 1;88(5):804-9.
Title: A novel MDM2 anti-sense oligonucleotide has anti-tumor activity and potentiates cytotoxic drugs acting by different mechanisms in human colon cancer.
Author: Tortora, G|Caputo, R|Damiano, V|Bianco, R|Chen, J|Agrawal, S|Bianco, A R|Ciardiello, F
PMID: 11072252
Journal: Am J Pathol. 2000 Dec;157(6):1947-53.
Title: Human colorectal cancers with an intact p16/cyclin D1/pRb pathway have up-regulated p16 expression and decreased proliferation in small invasive tumor clusters.
Author: Palmqvist, R|Rutegard, J N|Bozoky, B|Landberg, G|Stenling, R
PMID: 11106567
Journal: Zhonghua Bing Li Xue Za Zhi. 2000 Apr;29(2):95-8.
Title: [Methylation status of p16 gene in colorectal carcinoma and normal colonic mucosa].
Author: Zhang, J|Lai, M|Chen, J
PMID: 11866898
Journal: Int J Cancer. 2001 Jan 15;91(2):205-12.
Title: DNA methyltransferase expression and DNA methylation of CPG islands and peri-centromeric satellite regions in human colorectal and stomach cancers.
Author: Kanai, Y|Ushijima, S|Kondo, Y|Nakanishi, Y|Hirohashi, S
PMID: 11146446
Journal: Cancer Lett. 2001 Feb 10;163(1):17-23.
Title: Mutations, methylation and expression of CDKN2a/p16 gene in colorectal cancer and normal colonic mucosa.
Author: Trzeciak, L|Hennig, E|Kolodziejski, J|Nowacki, M|Ostrowski, J
PMID: 11163104
Journal: J Clin Oncol. 2001 Jan 15;19(2):299-304.
Title: K-ras and p16 aberrations confer poor prognosis in human colorectal cancer.
Author: Esteller, M|Gonzalez, S|Risques, R A|Marcuello, E|Mangues, R|Germa, J R|Herman, J G|Capella, G|Peinado, M A
PMID: 11208819
Journal: Lab Invest. 2001 Feb;81(2):217-29.
Title: Methylation silencing and mutations of the p14ARF and p16INK4a genes in colon cancer.
Author: Burri, N|Shaw, P|Bouzourene, H|Sordat, I|Sordat, B|Gillet, M|Schorderet, D|Bosman, F T|Chaubert, P
PMID: 11232644
Journal: J Natl Cancer Inst. 2001 Mar 21;93(6):436-46.
Title: Selective in vivo and in vitro effects of a small molecule inhibitor of cyclin-dependent kinase 4.
Author: Soni, R|O'Reilly, T|Furet, P|Muller, L|Stephan, C|Zumstein-Mecker, S|Fretz, H|Fabbro, D|Chaudhuri, B
PMID: 11259469
Journal: Cancer Res. 2001 Apr 1;61(7):2816-21.
Title: p14ARF silencing by promoter hypermethylation mediates abnormal intracellular localization of MDM2.
Author: Esteller, M|Cordon-Cardo, C|Corn, P G|Meltzer, S J|Pohar, K S|Watkins, D N|Capella, G|Peinado, M A|Matias-Guiu, X|Prat, J|Baylin, S B|Herman, J G
PMID: 11306450
Journal: Cancer Lett. 2001 Jun 10;167(1):91-7.
Title: Methylation of the hMLH1, p16, and MDR1 genes in colorectal carcinoma: associations with clinicopathological features.
Author: Shannon, B A|Iacopetta, B J
PMID: 11323103
Journal: Cancer Res. 2001 May 1;61(9):3573-7.
Title: Accelerated age-related CpG island methylation in ulcerative colitis.
Author: Issa, J P|Ahuja, N|Toyota, M|Bronner, M P|Brentnall, T A
PMID: 11325821
Journal: Clin Chem Lab Med. 2001 Feb;39(2):121-8.
Title: Heterogeneity of DNA methylation status analyzed by bisulfite-PCR-SSCP and correlation with clinico-pathological characteristics in colorectal cancer.
Author: Maekawa, M|Sugano, K|Ushiama, M|Fukayama, N|Nomoto, K|Kashiwabara, H|Fujita, S|Kakizoe, T
PMID: 11341745
Journal: Mol Cell Probes. 2001 Jun;15(3):183-5.
Title: A novel highly informative polyA microsatellite on the telomeric side of the INK4a/ARF locus.
Author: Chaubert, P|Burri, N|Cousin, P|Shaw, P
PMID: 11352600
Journal: Langenbecks Arch Surg. 2001 Apr;386(3):163-71.
Title: Carcinogenesis of cancer of the papilla and ampulla: pathophysiological facts and molecular biological mechanisms.
Author: Esposito, I|Friess, H|Buchler, M W
PMID: 11382316
Journal: Am J Pathol. 2001 Sep;159(3):1129-35.
Title: CpG island methylation in colorectal adenomas.
Author: Rashid, A|Shen, L|Morris, J S|Issa, J P|Hamilton, S R
PMID: 11549606
Journal: J Natl Cancer Inst. 2001 Oct 3;93(19):1465-72.
Title: Susceptibility of nonpromoter CpG islands to de novo methylation in normal and neoplastic cells.
Author: Nguyen, C|Liang, G|Nguyen, T T|Tsao-Wei, D|Groshen, S|Lubbert, M|Zhou, J H|Benedict, W F|Jones, P A
PMID: 11584062
Journal: Melanoma Res. 2001 Oct;11(5):447-9.
Title: CDKN2A novel mutation in a patient from a melanoma-prone family.
Author: Grammatico, P|Binni, F|Eibenschutz, L|De Bernardo, C|Grammatico, B|Rinaldi, R|De Simone, P|Catricala, C
PMID: 11595880
Journal: Acta Oncol. 2001;40(5):633-7.
Title: Microsatellite instability, PTEN and p53 germline mutations in glioma families.
Author: Malmer, B|Gronberg, H|Andersson, U|Jonsson, B A|Henriksson, R
PMID: 11669337
Journal: Chin Med J (Engl). 2001 Oct;114(10):1068-72.
Title: Telomerase activity and homozygous deletions of the p16 gene in liver metastases of colorectal carcinoma.
Author: Ma, J|Zhan, W|Peng, J|He, Y|Zheng, Z|Cai, S|Wang, L|Wang, J
PMID: 11677769
Journal: Hum Mol Genet. 2001 Dec 15;10(26):3001-7.
Title: DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis.
Author: Esteller, M|Fraga, M F|Guo, M|Garcia-Foncillas, J|Hedenfalk, I|Godwin, A K|Trojan, J|Vaurs-Barriere, C|Bignon, Y J|Ramus, S|Benitez, J|Caldes, T|Akiyama, Y|Yuasa, Y|Launonen, V|Canal, M J|Rodriguez, R|Capella, G|Peinado, M A|Borg, A|Aaltonen, L A|Ponder,
PMID: 11751682
Journal: World J Gastroenterol. 2001 Oct;7(5):722-5.
Title: p16 gene methylation in colorectal cancers associated with Duke's staging.
Author: Yi, J|Wang, Z W|Cang, H|Chen, Y Y|Zhao, R|Yu, B M|Tang, X M
PMID: 11819863
Journal: Clin Cancer Res. 2002 Jan;8(1):17-21.
Title: The potential prognostic, predictive, and therapeutic values of DNA methylation in cancer. Commentary re: J. Kwong et al., Promoter hypermethylation of multiple genes in nasopharyngeal carcinoma. Clin. Cancer Res., 8: 131-137, 2002, and H-Z. Zou et al., D
Author: Widschwendter, Martin|Jones, Peter A
PMID: 11801535
Journal: Clin Cancer Res. 2002 Jan;8(1):188-91.
Title: Detection of aberrant p16 methylation in the serum of colorectal cancer patients.
Author: Zou, Hong-Zhi|Yu, Bao-Ming|Wang, Zhi-Wei|Sun, Ji-Yuan|Cang, Hui|Gao, Fei|Li, Dong Hua|Zhao, Ren|Feng, Guo-Guang|Yi, Jing
PMID: 11801557
Journal: Curr Opin Oncol. 2002 Mar;14(2):171-9.
Title: Translational oncogenomics: toward rational therapeutic decision-making.
Author: Rosell, Rafael|Monzo, Mariano|O'Brate, Aurora|Taron, Miquel
PMID: 11880707
Journal: Am J Surg Pathol. 2002 Apr;26(4):472-8.
Title: Evaluation of molecular markers in low-grade diffuse astrocytomas: loss of p16 and retinoblastoma protein expression is associated with short survival.
Author: Hilton, David A|Penney, Mark|Evans, Barry|Sanders, Hilary|Love, Seth
PMID: 11914625
Journal: J Pathol. 2002 Apr;196(4):386-93.
Title: Analysis of key cell-cycle checkpoint proteins in colorectal tumours.
Author: McKay, Judith A|Douglas, Joy J|Ross, Val G|Curran, Stephanie|Loane, Joseph F|Ahmed, Fareeda Y|Cassidy, Jim|McLeod, Howard L|Murray, Graeme I
PMID: 11920733
Journal: Jpn J Clin Oncol. 2002 Jan;32(1):3-8.
Title: Methylation status and expression of human telomerase reverse transcriptase mRNA in relation to hypermethylation of the p16 gene in colorectal cancers as analyzed by bisulfite PCR-SSCP.
Author: Nomoto, Kiyoaki|Maekawa, Masato|Sugano, Kokichi|Ushiama, Mineko|Fukayama, Noriko|Fujita, Shin|Kakizoe, Tadao
PMID: 11932355
Journal: Nature. 2002 Apr 4;416(6880):552-6.
Title: DNMT1 and DNMT3b cooperate to silence genes in human cancer cells.
Author: Rhee, Ina|Bachman, Kurtis E|Park, Ben Ho|Jair, Kam-Wing|Yen, Ray-Whay Chiu|Schuebel, Kornel E|Cui, Hengmi|Feinberg, Andrew P|Lengauer, Christoph|Kinzler, Kenneth W|Baylin, Stephen B|Vogelstein, Bert
PMID: 11932749
Journal: Gastroenterology. 2002 May;122(5):1376-87.
Title: CpG island methylation in sporadic colorectal cancers and its relationship to microsatellite instability.
Author: Hawkins, Nicholas|Norrie, Mark|Cheong, Kay|Mokany, Elisa|Ku, Su-Lyn|Meagher, Alan|O'Connor, Terence|Ward, Robyn
PMID: 11984524
Journal: Am J Pathol. 2002 May;160(5):1823-30.
Title: CpG island methylation in aberrant crypt foci of the colorectum.
Author: Chan, Annie On-On|Broaddus, Russell R|Houlihan, Patrick S|Issa, Jean-Pierre J|Hamilton, Stanley R|Rashid, Asif
PMID: 12000733
Journal: Oncogene. 2002 May 9;21(20):3149-61.
Title: Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis.
Author: Hemmati, Philipp G|Gillissen, Bernhard|von Haefen, Clarissa|Wendt, Jana|Starck, Lilian|Guner, Dilek|Dorken, Bernd|Daniel, Peter T
PMID: 12082630
Journal: Oncogene. 2002 May 9;21(20):3207-12.
Title: Human p14(ARF)-mediated cell cycle arrest strictly depends on intact p53 signaling pathways.
Author: Weber, H Oliver|Samuel, Temesgen|Rauch, Pia|Funk, Jens Oliver
PMID: 12082636
Journal: Cancer Res. 2002 Jul 15;62(14):3997-4006.
Title: Growth inhibition of human hepatoma cells by acyclic retinoid is associated with induction of p21(CIP1) and inhibition of expression of cyclin D1.
Author: Suzui, Masumi|Masuda, Muneyuki|Lim, Jin T E|Albanese, Chris|Pestell, Richard G|Weinstein, I Bernard
PMID: 12124333
Journal: Int J Cancer. 2002 Aug 10;100(5):542-8.
Title: Detection of free-circulating tumor-associated DNA in plasma of colorectal cancer patients and its association with prognosis.
Author: Lecomte, Thierry|Berger, Anne|Zinzindohoue, Franck|Micard, Stephanie|Landi, Bruno|Blons, Helene|Beaune, Philippe|Cugnenc, Paul-Henri|Laurent-Puig, Pierre
PMID: 12124803
Journal: Cancer Gene Ther. 2002 Aug;9(8):641-50.
Title: Adenovirus-mediated gene transfer of P16INK4/CDKN2 into bax-negative colon cancer cells induces apoptosis and tumor regression in vivo.
Author: Tamm, Ingo|Schumacher, Axel|Karawajew, Leonid|Ruppert, Velia|Arnold, Wolfgang|Nussler, Andreas K|Neuhaus, Peter|Dorken, Bernd|Wolff, Gerhard
PMID: 12136424
Journal: J Biol Chem. 2002 Oct 4;277(40):37949-54. Epub 2002 Jul 31.
Title: Inactivation of p21WAF1 sensitizes cells to apoptosis via an increase of both p14ARF and p53 levels and an alteration of the Bax/Bcl-2 ratio.
Author: Javelaud, Delphine|Besancon, Francoise
PMID: 12151395
Journal: Carcinogenesis. 2002 Sep;23(9):1447-54.
Title: Altered expression of c-myc, p16 and p27 in rat colon tumors and its reversal by short-term treatment with chemopreventive agents.
Author: Tao, Lianhui|Kramer, Paula M|Wang, Wei|Yang, Siming|Lubet, Ronald A|Steele, Vernon E|Pereira, Michael A
PMID: 12189186
Journal: Oncogene. 2002 Oct 17;21(47):7277-82.
Title: Frequent RASSF1A tumour suppressor gene promoter methylation in Wilms' tumour and colorectal cancer.
Author: Wagner, Kate J|Cooper, Wendy N|Grundy, Richard G|Caldwell, Germaine|Jones, Carolyn|Wadey, Roy B|Morton, Dion|Schofield, Paul N|Reik, Wolf|Latif, Farida|Maher, Eamonn R
PMID: 12370819
Journal: Gastroenterology. 2002 Nov;123(5):1478-84.
Title: Prognostic significance of calcium-binding protein S100A4 in colorectal cancer.
Author: Gongoll, Silvia|Peters, Gerrit|Mengel, Michael|Piso, Pompiliu|Klempnauer, Jurgen|Kreipe, Hans|von Wasielewski, Reinhard
PMID: 12404222
Journal: Cancer Lett. 2002 Dec 15;188(1-2):115-9.
Title: Molecular detection of p16 promoter methylation in the serum of colorectal cancer patients.
Author: Nakayama, Hiroshi|Hibi, Kenji|Taguchi, Masumi|Takase, Tsunenobu|Yamazaki, Taiji|Kasai, Yasushi|Ito, Katsuki|Akiyama, Seiji|Nakao, Akimasa
PMID: 12406556
Journal: Zhonghua Yu Fang Yi Xue Za Zhi. 2002 Dec;36(7):499-501.
Title: Detection of aberrant p16 methylation in the serum of colorectal cancer patients.
Author: Zou, Hongzhi|Yu, Baoming|Zhao, Ren|Wang, Zhiwei|Cang, Hui|Li, Donghua|Feng, Guoguang|Yi, Jing
PMID: 12411153
Journal: Cancer Res. 2002 Nov 1;62(21):6011-4.
Title: Morphological and molecular heterogeneity within nonmicrosatellite instability-high colorectal cancer.
Author: Whitehall, Vicki L J|Wynter, Coral V A|Walsh, Michael D|Simms, Lisa A|Purdie, David|Pandeya, Nirmala|Young, Joanne|Meltzer, Stephen J|Leggett, Barbara A|Jass, Jeremy R
PMID: 12414620
Journal: Jpn J Cancer Res. 2002 Nov;93(11):1266-9.
Title: Detection of tumor DNA in serum of colorectal cancer patients.
Author: Ito, Seiji|Hibi, Kenji|Nakayama, Hiroshi|Kodera, Yasuhiro|Ito, Katsuki|Akiyama, Seiji|Nakao, Akimasa
PMID: 12460469
Journal: Jpn J Cancer Res. 2002 Aug;93(8):883-7.
Title: Colorectal cancers with both p16 and p14 methylation show invasive characteristics.
Author: Hibi, Kenji|Nakayama, Hiroshi|Koike, Masahiko|Kasai, Yasushi|Ito, Katsuki|Akiyama, Seiji|Nakao, Akimasa
PMID: 12716465
Journal: J Biol Chem. 2003 Mar 7;278(10):8238-43. Epub 2002 Dec 10.
Title: A potent cell-active allosteric inhibitor of murine DNA cytosine C5 methyltransferase.
Author: Flynn, James|Fang, Jing-Yuan|Mikovits, Judy A|Reich, Norbert O
PMID: 12477724
Journal: Mol Cell Biol. 2003 Jan;23(1):206-15.
Title: Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer.
Author: Kondo, Yutaka|Shen, LanLan|Issa, Jean-Pierre J
PMID: 12482974
Journal: Nat Genet. 2003 Jan;33(1):61-5. Epub 2002 Dec 23.
Title: DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells.
Author: Robert, Marie-France|Morin, Steves|Beaulieu, Normand|Gauthier, France|Chute, Ian C|Barsalou, Annie|MacLeod, A Robert
PMID: 12496760
Journal: J Clin Pathol. 2003 Jan;56(1):69-73.
Title: APC mutation and tumour budding in colorectal cancer.
Author: Jass, J R|Barker, M|Fraser, L|Walsh, M D|Whitehall, V L J|Gabrielli, B|Young, J|Leggett, B A
PMID: 12499439
Journal: Br J Cancer. 2003 Feb 10;88(3):413-9.
Title: CpG island methylation is a common finding in colorectal cancer cell lines.
Author: Suter, C M|Norrie, M|Ku, S L|Cheong, K F|Tomlinson, I|Ward, R L
PMID: 12569385
Journal: Mol Cancer Ther. 2003 Feb;2(2):139-50.
Title: Flavopiridol induces apoptosis in glioma cell lines independent of retinoblastoma and p53 tumor suppressor pathway alterations by a caspase-independent pathway.
Author: Alonso, Michelle|Tamasdan, Cristina|Miller, Douglas C|Newcomb, Elizabeth W
PMID: 12589031
Journal: Cancer Res. 2003 Feb 15;63(4):742-6.
Title: Inhibition of colon tumor progression and angiogenesis by the Ink4a/Arf locus.
Author: Gibson, Steven L|Dai, Charlotte Y|Lee, Han-Woong|DePinho, Ronald A|Gee, Michael S|Lee, William M F|Furth, Emma E|Brensinger, Colleen|Enders, Greg H
PMID: 12591718
Journal: Am J Pathol. 2003 Mar;162(3):815-22.
Title: Frequent CpG island methylation in serrated adenomas of the colorectum.
Author: Park, Seun-Ja|Rashid, Asif|Lee, Jae-Hyuk|Kim, Sang Geol|Hamilton, Stanley R|Wu, Tsung-Teh
PMID: 12598316
Journal: Cancer Res. 2003 Mar 1;63(5):1054-8.
Title: SLIT2 axon guidance molecule is frequently inactivated in colorectal cancer and suppresses growth of colorectal carcinoma cells.
Author: Dallol, Ashraf|Morton, Dion|Maher, Eamonn R|Latif, Farida
PMID: 12615722
Journal: Clin Cancer Res. 2003 Mar;9(3):1112-7.
Title: High incidence of microsatellite instability in colorectal cancer from African Americans.
Author: Ashktorab, Hassan|Smoot, Duane T|Carethers, John M|Rahmanian, Majid|Kittles, Rick|Vosganian, Greg|Doura, Menaham|Nidhiry, Emmanel|Naab, Tammy|Momen, Bahram|Shakhani, Shahid|Giardiello, Francis M
PMID: 12631615
Journal: Gastroenterology. 2003 Apr;124(4):1165-6.
Title: Gender difference for promoter methylation pattern of hMLH1 and p16 in sporadic MSI colorectal cancer.
Author: Laghi, Luigi|Bianchi, Paolo|Malesci, Alberto
PMID: 12671921
Journal: Cancer. 2003 Apr 15;97(8 Suppl):2083-9.
Title: Molecular targeting and pharmacogenomics in the management of advanced bladder cancer.
Author: Raghavan, Derek
PMID: 12673700
Journal: Int J Cancer. 2003 Jul 1;105(4):491-3.
Title: Molecular detection of p16 promoter methylation in the serum of recurrent colorectal cancer patients.
Author: Nakayama, Hiroshi|Hibi, Kenji|Takase, Tsunenobu|Yamazaki, Taiji|Kasai, Yasushi|Ito, Katsuki|Akiyama, Seiji|Nakao, Akimasa
PMID: 12712439
Journal: Oncol Rep. 2003 Jul-Aug;10(4):935-8.
Title: Hypermethylation of the CDKN2A gene in colorectal cancer is associated with shorter survival.
Author: Maeda, Kazuya|Kawakami, Kazuyuki|Ishida, Yoshinori|Ishiguro, Kaname|Omura, Kenji|Watanabe, Go
PMID: 12792748
Journal: Cancer Res. 2003 Jun 15;63(12):3133-7.
Title: Effects of dietary folate and alcohol intake on promoter methylation in sporadic colorectal cancer: the Netherlands cohort study on diet and cancer.
Author: van Engeland, Manon|Weijenberg, Matty P|Roemen, Guido M J M|Brink, Mirian|de Bruine, Adriaan P|Goldbohm, R Alexandra|van den Brandt, Piet A|Baylin, Stephen B|de Goeij, Anton F P M|Herman, James G
PMID: 12810640
Journal: J Natl Cancer Inst. 2003 Jul 2;95(13):948-60.
Title: Etiology of pancreatic cancer, with a hypothesis concerning the role of N-nitroso compounds and excess gastric acidity.
Author: Risch, Harvey A
PMID: 12837831
Journal: Int J Oncol. 2003 Oct;23(4):1009-13.
Title: Differences in loss of p16INK4 protein expression by promoter methylation between left- and right-sided primary colorectal carcinomas.
Author: Schneider-Stock, Regine|Boltze, Carsten|Peters, Brigitte|Hopfner, Tino|Meyer, Frank|Lippert, Hans|Roessner, Albert
PMID: 12963980
Journal: World J Gastroenterol. 2003 Sep;9(9):1976-80.
Title: Effects of DNA methylation on expression of tumor suppressor genes and proto-oncogene in human colon cancer cell lines.
Author: Fang, Jing-Yuan|Lu, Juan|Chen, Ying-Xuan|Yang, Li
PMID: 12970888
Journal: J Clin Oncol. 2003 Oct 15;21(20):3729-36.
Title: Adverse prognostic effect of methylation in colorectal cancer is reversed by microsatellite instability.
Author: Ward, Robyn Lynne|Cheong, Kay|Ku, Su-Lyn|Meagher, Alan|O'Connor, Terence|Hawkins, Nicholas John
PMID: 14551292
Journal: Dig Dis Sci. 2003 Sep;48(9):1745-50.
Title: Glucocorticoid receptor (GR) immunohistochemical expression is correlated with cell cycle-related molecules in human colon cancer.
Author: Theocharis, Stamatios|Kouraklis, Gregorios|Margeli, Alexandra|Agapitos, Emmanuel|Ninos, Sotirios|Karatzas, Gabriel|Koutselinis, Antonios
PMID: 14560994
Journal: World J Gastroenterol. 2003 Oct;9(10):2202-6.
Title: Expressing patterns of p16 and CDK4 correlated to prognosis in colorectal carcinoma.
Author: Zhao, Po|Hu, Ying-Chuan|Talbot, Ian C
PMID: 14562378
Journal: J Surg Oncol. 2003 Nov;84(3):143-50.
Title: Inactivation of p16INK4a by CpG hypermethylation is not a frequent event in colorectal cancer.
Author: Norrie, Mark W A|Hawkins, Nicholas J|Todd, Alison V|Meagher, Alan P|O'Connor, Terence W|Ward, Robyn L
PMID: 14598358
Journal: Int J Cancer. 2003 Dec 20;107(6):896-902.
Title: Heterogeneous expression and association of beta-catenin, p16 and c-myc in multistage colorectal tumorigenesis and progression detected by tissue microarray.
Author: Xie, Dan|Sham, Jonathan S T|Zeng, Wei-Fen|Lin, Han-Liang|Che, Li-Hong|Wu, Hui-Xi|Wen, Jian-Ming|Fang, Yan|Hu, Liang|Guan, Xin-Yuan
PMID: 14601048
Journal: Cancer Res. 2003 Nov 15;63(22):7563-70.
Title: Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines.
Author: Fang, Ming Zhu|Wang, Yimin|Ai, Ni|Hou, Zhe|Sun, Yi|Lu, Hong|Welsh, William|Yang, Chung S
PMID: 14633667
Journal: World J Gastroenterol. 2003 Dec;9(12):2642-9.
Title: Aberrant crypt foci as microscopic precursors of colorectal cancer.
Author: Cheng, Lei|Lai, Mao-De
PMID: 14669304
Journal: Clin Cancer Res. 2003 Dec 15;9(17):6410-8.
Title: Identification of HRK as a target of epigenetic inactivation in colorectal and gastric cancer.
Author: Obata, Toshiro|Toyota, Minoru|Satoh, Ayumi|Sasaki, Yasushi|Ogi, Kazuhiro|Akino, Kimishige|Suzuki, Hiromu|Murai, Masafumi|Kikuchi, Takefumi|Mita, Hiroaki|Itoh, Fumio|Issa, Jean-Pierre J|Tokino, Takashi|Imai, Kohzoh
PMID: 14695142
Journal: Hepatogastroenterology. 2003 Nov-Dec;50(54):1756-60.
Title: Reduced p16 expression correlates with lymphatic invasion in colorectal cancers.
Author: Tada, Tomohiro|Watanabe, Toshiaki|Kazama, Shinsuke|Kanazawa, Takamitsu|Hata, Keisuke|Komuro, Yasuhiro|Nagawa, Hirokazu
PMID: 14696398
Journal: Zhonghua Yi Xue Za Zhi. 2003 Dec 10;83(23):2077-82.
Title: [The study of 5-Aza-2'-deoxycytidine on transcription regulation of p16/CDKN2 gene demethylation in RKO human colorectal cell line].
Author: Fang, Xiao-ming|Sun, Li-feng|Peng, Jia-ping|Dong, Qi|Zheng, Shu
PMID: 14703421
Journal: Oncol Rep. 2004 Feb;11(2):341-8.
Title: Promoter CpG methylation of tumor suppressor genes in colorectal cancer and its relationship to clinical features.
Author: Lin, Shyr-Yi|Yeh, Kun-Tu|Chen, Willian Tzu-Liang|Chen, Hung-Chang|Chen, Shou-Tung|Chiou, Hung-Yi|Chang, Jan-Gowth
PMID: 14719065
Journal: Int J Oncol. 2004 Feb;24(2):349-55.
Title: Differential impact of p16 inactivation by promoter methylation in non-small cell lung and colorectal cancer: clinical implications.
Author: Gonzalez-Quevedo, Rosa|Garcia-Aranda, Cristina|Moran, Alberto|De Juan, Carmen|Sanchez-Pernaute, Andres|Torres, Antonio|Diaz-Rubio, Eduardo|Balibrea, Jose-Luis|Benito, Manuel|Iniesta, Pilar
PMID: 14719111
Journal: Cancer Lett. 2004 Jan 20;203(2):217-24.
Title: The Bmi-1 oncoprotein is overexpressed in human colorectal cancer and correlates with the reduced p16INK4a/p14ARF proteins.
Author: Kim, Joo Heon|Yoon, Sun Young|Kim, Chang-Nam|Joo, Joung Hyuck|Moon, Sang Kyoung|Choe, In Seong|Choe, Yong-Kyung|Kim, Jae Wha
PMID: 14732230
Journal: Am J Clin Oncol. 2004 Feb;27(1):39-45.
Title: Simultaneous mutations in K-ras and TP53 are indicative of poor prognosis in sporadic colorectal cancer.
Author: Gonzalez-Aguilera, Juan J|Oliart, Soledad|Azcoita, Mariano Moreno|Fernandez-Peralta, Antonia M
PMID: 14758132
Journal: Clin Cancer Res. 2004 Mar 1;10(5):1698-705.
Title: Epstein-barr virus-positive gastric carcinoma has a distinct protein expression profile in comparison with epstein-barr virus-negative carcinoma.
Author: Lee, Hye Seung|Chang, Mee Soo|Yang, Han-Kwang|Lee, Byung Lan|Kim, Woo Ho
PMID: 15014022
Journal: Gut. 2004 Apr;53(4):573-80.
Title: Methylation patterns define two types of hyperplastic polyp associated with colorectal cancer.
Author: Wynter, C V A|Walsh, M D|Higuchi, T|Leggett, B A|Young, J|Jass, J R
PMID: 15016754
Journal: Zhonghua Yi Xue Za Zhi. 2004 Feb 17;84(4):312-7.
Title: [Regulation of histone acetylation on the expression of cell cycle-associated genes in human colon cancer cell lines].
Author: Chen, Ying-xuan|Fang, Jing-yuan|Lu, Juan|Qiu, De-kai
PMID: 15059516
Journal: Oncogene. 2004 Jul 8;23(31):5340-9.
Title: Histone deacetylase inhibitors activate INK4d gene through Sp1 site in its promoter.
Author: Yokota, Tomoya|Matsuzaki, Youichirou|Miyazawa, Kazuhiro|Zindy, Frederique|Roussel, Martine F|Sakai, Toshiyuki
PMID: 15107822
Journal: Lab Invest. 2004 Jul;84(7):884-93.
Title: Aberrant CpG island hypermethylation of multiple genes in colorectal neoplasia.
Author: Lee, Sun|Hwang, Kyu Sang|Lee, Hyeon Joo|Kim, Jung-Sun|Kang, Gyeong Hoon
PMID: 15122305
Journal: Anticancer Res. 2004 Mar-Apr;24(2B):649-54.
Title: The association between methylenetetrahydrofolate reductase polymorphism and promoter methylation in proximal colon cancer.
Author: Oyama, Kaeko|Kawakami, Kazuyuki|Maeda, Kazuya|Ishiguro, Kaname|Watanabe, Go
PMID: 15161007
Journal: Biotech Histochem. 2004 Feb;79(1):5-10.
Title: Electron microscopy evidence that cytoplasmic localization of the p16(INK4A) "nuclear" cyclin-dependent kinase inhibitor (CKI) in tumor cells is specific and not an artifact. A study in non-small cell lung carcinomas.
Author: Evangelou, K|Bramis, J|Peros, I|Zacharatos, P|Dasiou-Plakida, D|Kalogeropoulos, N|Asimacopoulos, P J|Kittas, C|Marinos, E|Gorgoulis, V G
PMID: 15223748
Journal: Clin Cancer Res. 2004 Jul 1;10(13):4444-9.
Title: Detection of lymph node micrometastases by gene promoter hypermethylation in samples obtained by endosonography- guided fine-needle aspiration biopsy.
Author: Pellise, Maria|Castells, Antoni|Gines, Angels|Agrelo, Ruben|Sole, Manel|Castellvi-Bel, Sergi|Fernandez-Esparrach, Gloria|Llach, Josep|Esteller, Manel|Bordas, Josep M|Pique, Josep M
PMID: 15240535
Journal: Mod Pathol. 2004 Dec;17(12):1464-74.
Title: Retinoblastoma protein function and p16INK4a expression in actinic keratosis, squamous cell carcinoma in situ and invasive squamous cell carcinoma of the skin and links between p16INK4a expression and infiltrative behavior.
Author: Nilsson, Kristina|Svensson, Sofie|Landberg, Goran
PMID: 15257310
Journal: Fam Cancer. 2004;3(2):101-7.
Title: Promoter hypermethylation frequency and BRAF mutations distinguish hereditary non-polyposis colon cancer from sporadic MSI-H colon cancer.
Author: McGivern, A|Wynter, C V A|Whitehall, V L J|Kambara, T|Spring, K J|Walsh, M D|Barker, M A|Arnold, S|Simms, L A|Leggett, B A|Young, J|Jass, J R
PMID: 15340260
Journal: Cancer Epidemiol Biomarkers Prev. 2004 Sep;13(9):1495-501.
Title: Use of DNA from human stools to detect aberrant CpG island methylation of genes implicated in colorectal cancer.
Author: Belshaw, Nigel J|Elliott, Giles O|Williams, Elizabeth A|Bradburn, David M|Mills, Sarah J|Mathers, John C|Johnson, Ian T
PMID: 15342451
Journal: Int J Oncol. 2004 Oct;25(4):913-20.
Title: Dysfunction of p53 pathway in human colorectal cancer: analysis of p53 gene mutation and the expression of the p53-associated factors p14ARF, p33ING1, p21WAF1 and MDM2.
Author: Tachibana, Masatsugu|Kawamata, Hitoshi|Fujimori, Takahiro|Omotehara, Fumie|Horiuchi, Hideki|Ohkura, Yasuo|Igarashi, Seiji|Kotake, Kenjiro|Kubota, Keiichi
PMID: 15375540
Journal: Mol Cancer. 2004 Oct 11;3:28.
Title: A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines.
Author: Lind, Guro E|Thorstensen, Lin|Lovig, Tone|Meling, Gunn I|Hamelin, Richard|Rognum, Torleiv O|Esteller, Manel|Lothe, Ragnhild A
PMID: 15476557
Journal: Cancer Res. 2004 Oct 15;64(20):7618-21.
Title: The CpG island methylator phenotype is not associated with a personal or family history of cancer.
Author: Ward, Robyn Lynne|Williams, Rachel|Law, Matthew|Hawkins, Nicholas John
PMID: 15492290
Journal: Int J Oncol. 2004 Nov;25(5):1447-52.
Title: p16INK4a polymorphism: associations with tumour progression in patients with sporadic colorectal cancer.
Author: McCloud, Jonathan M|Sivakumar, Rangasamy|Greenhough, Alex|Elder, Jackie|Jones, Peter W|Deakin, Mark|Elder, James B|Fryer, Anthony A|Hoban, Paul R
PMID: 15492837
Journal: Hum Pathol. 2004 Oct;35(10):1171-2.
Title: Prognostic significance of pRb family and p16(INK4) alterations in colorectal cancer: an interesting point of view in a complex net of molecular signals.
Author: Giordano, Antonio|Macaluso, Marcella
PMID: 15492982
Journal: Hum Pathol. 2004 Oct;35(10):1189-95.
Title: Aberrant expression of pRb and p16(INK4), alone or in combination, indicates poor outcome after resection in patients with colorectal carcinoma.
Author: Cui, Xing|Shirai, Yoshio|Wakai, Toshifumi|Yokoyama, Naoyuki|Hirano, Seishiro|Hatakeyama, Katsuyoshi
PMID: 15492985
Journal: World J Gastroenterol. 2004 Dec 1;10(23):3441-54.
Title: Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis.
Author: Xu, Xiao-Li|Yu, Jian|Zhang, Hong-Yu|Sun, Meng-Hong|Gu, Jun|Du, Xiang|Shi, Da-Ren|Wang, Peng|Yang, Zhen-Hua|Zhu, Jing-De
PMID: 15526363
Journal: J Clin Oncol. 2004 Nov 15;22(22):4584-94.
Title: Colorectal cancer with mutation in BRAF, KRAS, and wild-type with respect to both oncogenes showing different patterns of DNA methylation.
Author: Nagasaka, Takeshi|Sasamoto, Hiromi|Notohara, Kenji|Cullings, Harry M|Takeda, Masanori|Kimura, Keigo|Kambara, Takeshi|MacPhee, Donald G|Young, Joanne|Leggett, Barbara A|Jass, Jeremy R|Tanaka, Noriaki|Matsubara, Nagahide
PMID: 15542810
Journal: Scand J Gastroenterol. 2004 Nov;39(11):1134-40.
Title: Genetic characterization of colorectal cancers in young patients based on chromosomal loss and microsatellite instability.
Author: Tada, T|Watanabe, T|Kanazawa, T|Kazama, S|Koketsu, S|Nagawa, H
PMID: 15545173
Journal: Jpn J Clin Oncol. 2004 Oct;34(10):594-601.
Title: Immunohistochemical evaluation of thymidylate synthase (TS) and p16INK4a in advanced colorectal cancer: implication of TS expression in 5-FU-based adjuvant chemotherapy.
Author: Kamoshida, Shingo|Matsuoka, Hiroshi|Ishikawa, Taro|Maeda, Kotaro|Shimomura, Ryoichi|Inada, Ken-ichi|Tsutsumi, Yutaka
PMID: 15591457
Journal: Mod Pathol. 2005 Feb;18(2):170-8.
Title: Progressive methylation during the serrated neoplasia pathway of the colorectum.
Author: Dong, Seung M|Lee, Eui J|Jeon, Eun S|Park, Cheol K|Kim, Kyoung-Mee
PMID: 15389252
Journal: Int J Cancer. 2005 Mar 10;114(1):58-73.
Title: Genotype phenotype correlations in Israeli colorectal cancer patients.
Author: Starinsky, Sigal|Figer, Arie|Ben-Asher, Edna|Geva, Ravit|Flex, Dov|Fidder, Herma H|Zidan, Jamal|Lancet, Doron|Friedman, Eitan
PMID: 15523694
Journal: J Pharmacol Exp Ther. 2005 Feb;312(2):525-36. Epub 2004 Nov 16.
Title: 5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms.
Author: Schneider-Stock, Regine|Diab-Assef, Mona|Rohrbeck, Astrid|Foltzer-Jourdainne, Charlotte|Boltze, Carsten|Hartig, Roland|Schonfeld, Peter|Roessner, Albert|Gali-Muhtasib, Hala
PMID: 15547111
Journal: Oncol Rep. 2005 Feb;13(2):325-8.
Title: Development and application of a multiplex PCR procedure for the detection of DNA methylation in colorectal cancer.
Author: Anacleto, Charles|Rossi, Benedito|Lopes, Ademar|Soares, Fernando A|Rocha, Jose Claudio C|Caballero, Otavia|Camargo, Anamaria A|Simpson, Andrew J G|Pena, Sergio D J
PMID: 15643519
Journal: Clin Cancer Res. 2005 Feb 1;11(3):1203-9.
Title: Aberrantly methylated CDKN2A, MGMT, and MLH1 in colon polyps and in fecal DNA from patients with colorectal polyps.
Author: Petko, Zsolt|Ghiassi, Mahan|Shuber, Anthony|Gorham, Janice|Smalley, Walter|Washington, M Kay|Schultenover, Stephen|Gautam, Shiva|Markowitz, Sanford D|Grady, William M
PMID: 15709190
Journal: Carcinogenesis. 2005 Jun;26(6):1152-6. Epub 2005 Mar 10.
Title: CHFR promoter hypermethylation in colon cancer correlates with the microsatellite instability phenotype.
Author: Brandes, Johann C|van Engeland, Manon|Wouters, Kim A D|Weijenberg, Matty P|Herman, James G
PMID: 15760919
Journal: Am J Surg Pathol. 2005 Apr;29(4):429-36.
Title: Phenotype of microsatellite-stable colorectal carcinomas with CpG island methylation.
Author: Chirieac, Lucian R|Shen, Lanlan|Catalano, Paul J|Issa, Jean-Pierre|Hamilton, Stanley R
PMID: 15767794
Journal: Am J Pathol. 2005 Apr;166(4):1069-75.
Title: BRAF mutations in aberrant crypt foci and hyperplastic polyposis.
Author: Beach, Robyn|Chan, Annie On-On|Wu, Tsung-Teh|White, Jill A|Morris, Jeffrey S|Lunagomez, Simon|Broaddus, Russell R|Issa, Jean-Pierre J|Hamilton, Stanley R|Rashid, Asif
PMID: 15793287
Journal: J Clin Oncol. 2005 Apr 1;23(10):2318-24.
Title: Low microsatellite instability is associated with poor prognosis in stage C colon cancer.
Author: Kohonen-Corish, Maija R J|Daniel, Joseph J|Chan, Charles|Lin, Betty P C|Kwun, Sun Young|Dent, Owen F|Dhillon, Varinderpal S|Trent, Ronald J A|Chapuis, Pierre H|Bokey, E Leslie
PMID: 15800322
Journal: Int J Oncol. 2005 May;26(5):1217-26.
Title: Methylation and expression of p16INK4 tumor suppressor gene in primary colorectal cancer tissues.
Author: Kim, Byung No|Yamamoto, Hirofumi|Ikeda, Kimimasa|Damdinsuren, Bazarragchaa|Sugita, Yurika|Ngan, Chew Yee|Fujie, Yujiro|Ogawa, Minoru|Hata, Taishi|Ikeda, Masataka|Ohue, Masayuki|Sekimoto, Mitsugu|Monden, Takushi|Matsuura, Nariaki|Monden, Morito
PMID: 15809712
Journal: Int J Cancer. 2005 Oct 10;116(6):914-9.
Title: Clinicopathological features and microsatellite instability (MSI) in colorectal cancers from African Americans.
Author: Ashktorab, Hassan|Smoot, Duane T|Farzanmehr, Haleh|Fidelia-Lambert, Marie|Momen, Bahram|Hylind, Linda|Iacosozio-Dononue, Christine|Carethers, John M|Goel, Ajay|Boland, C Richard|Giardiello, Francis M
PMID: 15856472
Journal: Nucleic Acids Res. 2005 Apr 28;33(8):e73.
Title: Array-based analysis of genomic DNA methylation patterns of the tumour suppressor gene p16INK4A promoter in colon carcinoma cell lines.
Author: Mund, Cora|Beier, Verena|Bewerunge, Peter|Dahms, Michael|Lyko, Frank|Hoheisel, Jorg D
PMID: 15860770
Journal: Cancer Epidemiol Biomarkers Prev. 2005 May;14(5):1219-23.
Title: Gene-specific methylation and subsequent risk of colorectal adenomas among participants of the polyp prevention trial.
Author: Woodson, Karen|Weisenberger, Daniel J|Campan, Mihaela|Laird, Peter W|Tangrea, Joseph|Johnson, Laura Lee|Schatzkin, Arthur|Lanza, Elaine
PMID: 15894675
Journal: Clin Cancer Res. 2005 Jun 15;11(12):4580-8.
Title: Activation of p53-dependent apoptosis by acute ablation of glycogen synthase kinase-3beta in colorectal cancer cells.
Author: Ghosh, Jagadish C|Altieri, Dario C
PMID: 15958644
Journal: Hepatogastroenterology. 2005 May-Jun;52(63):666-71.
Title: Evaluating the combination of molecular prognostic factors in tumor radiosensitivity in rectal cancer.
Author: Komuro, Yasuhiro|Watanabe, Toshiaki|Tsurita, Giichiro|Muto, Tetsuichiro|Nagawa, Hirokazu
PMID: 15966178
Journal: Neoplasia. 2005 Apr;7(4):331-5.
Title: Colorectal cancer "methylator phenotype": fact or artifact?
Author: Anacleto, Charles|Leopoldino, Andreia M|Rossi, Benedito|Soares, Fernando A|Lopes, Ademar|Rocha, Jose Claudio C|Caballero, Otavia|Camargo, Anamaria A|Simpson, Andrew J G|Pena, Sergio D J
PMID: 15967110
Journal: J Biol Chem. 2005 Sep 9;280(36):32018-25. Epub 2005 Jul 6.
Title: Cyclin-dependent kinase inhibitors uncouple cell cycle progression from mitochondrial apoptotic functions in DNA-damaged cancer cells.
Author: Le, Hong-Van|Minn, Andy J|Massague, Joan
PMID: 16002406
Journal: Gastroenterology. 2005 Sep;129(3):837-45.
Title: Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer.
Author: Samowitz, Wade S|Albertsen, Hans|Herrick, Jennifer|Levin, Theodore R|Sweeney, Carol|Murtaugh, Maureen A|Wolff, Roger K|Slattery, Martha L
PMID: 16143123
Journal: Neoplasia. 2005 Aug;7(8):771-8.
Title: Hypermethylation of the TPEF/HPP1 gene in primary and metastatic colorectal cancers.
Author: Ebert, Matthias P A|Mooney, Suzanne H|Tonnes-Priddy, Lori|Lograsso, Joe|Hoffmann, Juliane|Chen, Jie|Rocken, Christoph|Schulz, Hans-Ulrich|Malfertheiner, Peter|Lofton-Day, Catherine
PMID: 16207479
Journal: Clin Cancer Res. 2005 Dec 1;11(23):8281-7.
Title: Differing DNA methylation patterns and gene mutation frequencies in colorectal carcinomas from Middle Eastern countries.
Author: Chan, Annie O|Soliman, Amr S|Zhang, Qing|Rashid, Asif|Bedeir, Ahmed|Houlihan, P Scott|Mokhtar, Nadia|Al-Masri, Nidal|Ozbek, Ugur|Yaghan, Rami|Kandilci, Ayten|Omar, Sherif|Kapran, Yersu|Dizdaroglu, Ferhunde|Bondy, Melissa L|Amos, Christopher I|Issa, Jean-P
PMID: 16322286
Journal: Cancer Biol Ther. 2005 Dec;4(12):1389-94. Epub 2005 Dec 9.
Title: p16(Ink4a) inhibits histologic progression and angiogenic signaling in min colon tumors.
Author: Gibson, Steven L|Boquoi, Amelie|Chen, Tina|Sharpless, Norman E|Brensinger, Colleen|Enders, Greg H
PMID: 16322687
Journal: Dig Dis. 2005;23(2):151-5.
Title: p16 Gene methylation in colorectal tumors: correlation with clinicopathological features and prognostic value.
Author: Sanz-Casla, M T|Maestro, M L|Vidaurreta, M|Maestro, C|Arroyo, M|Cerdan, J
PMID: 16352895
Journal: Mod Pathol. 2006 Jan;19(1):59-68.
Title: Distinct molecular features of colorectal carcinoma with signet ring cell component and colorectal carcinoma with mucinous component.
Author: Ogino, Shuji|Brahmandam, Mohan|Cantor, Mami|Namgyal, Chungdak|Kawasaki, Takako|Kirkner, Gregory|Meyerhardt, Jeffrey A|Loda, Massimo|Fuchs, Charles S
PMID: 16118624
Journal: Int J Cancer. 2006 Feb 15;118(4):907-15.
Title: DNA methylation patterns in adenomas from FAP, multiple adenoma and sporadic colorectal carcinoma patients.
Author: Wynter, Coral V A|Kambara, Takeshi|Walsh, Michael D|Leggett, Barbara A|Young, Joanne|Jass, Jeremy R
PMID: 16152625
Journal: Oncogene. 2006 Jan 26;25(4):503-11.
Title: Senescence and telomere shortening induced by novel potent G-quadruplex interactive agents, quindoline derivatives, in human cancer cell lines.
Author: Zhou, J-M|Zhu, X-F|Lu, Y-J|Deng, R|Huang, Z-S|Mei, Y-P|Wang, Y|Huang, W-L|Liu, Z-C|Gu, L-Q|Zeng, Y-X
PMID: 16170347
Journal: Genome Res. 2006 Feb;16(2):282-9.
Title: Multiplexed profiling of candidate genes for CpG island methylation status using a flexible PCR/LDR/Universal Array assay.
Author: Cheng, Yu-Wei|Shawber, Carrie|Notterman, Dan|Paty, Philip|Barany, Francis
PMID: 16369045
Journal: J Invest Dermatol. 2006 Feb;126(2):422-31.
Title: Epigenetic inactivation of tumor suppressor genes in serum of patients with cutaneous melanoma.
Author: Marini, Alessandra|Mirmohammadsadegh, Alireza|Nambiar, Sandeep|Gustrau, Annett|Ruzicka, Thomas|Hengge, Ulrich R
PMID: 16374457
Journal: Int J Cancer. 2006 Jun 15;118(12):3180-2.
Title: CDKN2A common variant and multi-organ cancer risk--a population-based study.
Author: Debniak, Tadeusz|Scott, Rodney J|Huzarski, Tomasz|Byrski, Tomasz|Rozmiarek, Andrzej|Debniak, Boguslaw|Gorski, Bohdan|Cybulski, Cezary|Medrek, Krzysztof|Mierzejewski, Marek|Masojc, Bartlomiej|Matyjasik, Joanna|Zlowocka, Elzbieta|Teodorczyk, Urszula|Lener,
PMID: 16395703
Journal: Gut. 2006 Jul;55(7):1000-6. Epub 2006 Jan 11.
Title: CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies.
Author: Ogino, S|Cantor, M|Kawasaki, T|Brahmandam, M|Kirkner, G J|Weisenberger, D J|Campan, M|Laird, P W|Loda, M|Fuchs, C S
PMID: 16407376
Journal: Br J Cancer. 2006 Feb 27;94(4):593-8.
Title: DNA hypermethylation in the normal colonic mucosa of patients with colorectal cancer.
Author: Kawakami, K|Ruszkiewicz, A|Bennett, G|Moore, J|Grieu, F|Watanabe, G|Iacopetta, B
PMID: 16421593
Journal: Anticancer Res. 2006 Jan-Feb;26(1A):55-8.
Title: Lymph node metastasis is infrequent in patients with highly-methylated colorectal cancer.
Author: Hibi, Kenji|Nakao, Akimasa
PMID: 16475679
Journal: Anticancer Res. 2006 Jan-Feb;26(1A):107-19.
Title: Aberrant crypt foci.
Author: Alrawi, Sadir J|Schiff, Michael|Carroll, Robert E|Dayton, Merril|Gibbs, John F|Kulavlat, Mahmood|Tan, Dongfeng|Berman, Kevin|Stoler, Daniel L|Anderson, Garth R
PMID: 16475686
Journal: Clin Cancer Res. 2006 Feb 15;12(4):1184-91.
Title: Profiling markers of prognosis in colorectal cancer.
Author: Lyall, Matthew S|Dundas, Sinclair R|Curran, Stephanie|Murray, Graeme I
PMID: 16489072
Journal: Br J Surg. 2006 Apr;93(4):395-406.
Title: Microsatellite instability in colorectal cancer.
Author: Soreide, K|Janssen, E A M|Soiland, H|Korner, H|Baak, J P A
PMID: 16555243
Journal: Dis Colon Rectum. 2006 May;49(5):588-94.
Title: Immunohistochemical expression of p16, p53, and p63 in colorectal adenomas and adenocarcinomas.
Author: Carneiro, Fabiana Pirani|Ramalho, Leandra Naira Zambelli|Britto-Garcia, Sergio|Ribeiro-Silva, Alfredo|Zucoloto, Sergio
PMID: 16575619
Journal: J Mol Diagn. 2006 May;8(2):193-201.
Title: Analysis of molecular alterations in left- and right-sided colorectal carcinomas reveals distinct pathways of carcinogenesis: proposal for new molecular profile of colorectal carcinomas.
Author: Sugai, Tamotsu|Habano, Wataru|Jiao, Yu-Fei|Tsukahara, Mitsunori|Takeda, Yuichiro|Otsuka, Koki|Nakamura, Shin-ichi
PMID: 16645205
Journal: J Mol Diagn. 2006 May;8(2):209-17.
Title: Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis.
Author: Ogino, Shuji|Kawasaki, Takako|Brahmandam, Mohan|Cantor, Mami|Kirkner, Gregory J|Spiegelman, Donna|Makrigiorgos, G Mike|Weisenberger, Daniel J|Laird, Peter W|Loda, Massimo|Fuchs, Charles S
PMID: 16645207
Journal: Hum Pathol. 2006 May;37(5):578-85.
Title: p16(INK4a) promoter methylation and 9p21 allelic loss in colorectal carcinomas: relation with immunohistochemical p16(INK4a) expression and with tumor budding.
Author: Prall, Friedrich|Ostwald, Christiane|Weirich, Volker|Nizze, Horst
PMID: 16647956
Journal: Pathol Res Pract. 2006;202(6):415-24.
Title: Prognostic value of p16INK4a and p14ARF gene hypermethylation in human colon cancer.
Author: Lee, Minjin|Sup Han, Woon|Kyoung Kim, Ok|Hee Sung, Sun|Sun Cho, Min|Lee, Shi Nae|Koo, Heasoo
PMID: 16675157
Journal: Mol Cancer Res. 2006 May;4(5):303-9.
Title: Methylation of p16 and Ras association domain family protein 1a during colorectal malignant transformation.
Author: Umetani, Naoyuki|de Maat, Michiel F G|Sunami, Eiji|Hiramatsu, Suzanne|Martinez, Steve|Hoon, Dave S B
PMID: 16687485
Journal: Mod Pathol. 2006 Aug;19(8):1083-90.
Title: Epigenetic profiling of synchronous colorectal neoplasias by quantitative DNA methylation analysis.
Author: Ogino, Shuji|Brahmandam, Mohan|Kawasaki, Takako|Kirkner, Gregory J|Loda, Massimo|Fuchs, Charles S
PMID: 16699497
Journal: Genes Chromosomes Cancer. 2006 Aug;45(8):781-9.
Title: CpG island methylation of genes accumulates during the adenoma progression step of the multistep pathogenesis of colorectal cancer.
Author: Kim, Young-Ho|Petko, Zsolt|Dzieciatkowski, Slavomir|Lin, Li|Ghiassi, Mahan|Stain, Steve|Chapman, William C|Washington, Mary Kay|Willis, Joseph|Markowitz, Sanford D|Grady, William M
PMID: 16708352
Journal: Am Surg. 2006 May;72(5):445-53.
Title: Microdissection-based allelotyping: a novel technique to determine the temporal sequence and biological aggressiveness of colorectal cancer.
Author: Gamblin, T Clark|Finkelstein, Sydney D|Upsal, Neil|Kaye, Jonathan D|Blumberg, David
PMID: 16719202
Journal: Ann Oncol. 2006 Jun;17 Suppl 7:vii137-41.
Title: Significance of P16INK4A hypermethylation gene in primary head/neck and colorectal tumors: it is a specific tissue event? Results of a 3-year GOIM (Gruppo Oncologico dell'Italia Meridionale) prospective study.
Author: Agnese, V|Corsale, S|Calo, V|Augello, C|Bruno, L|Calcara, D|Crosta, A|Rodolico, V|Rinaldi, G|Cicero, G|Latteri, F|Agrusa, A|Morello, V|Adamo, V|Altavilla, G|Di Fede, G|Fiorentino, E|Grassi, N|Latteri, M A|Valerio, M R|Tomasino, R M|Colucci, G|Bazan, V|Rus
PMID: 16760277
Journal: Ann Oncol. 2006 Jun;17 Suppl 7:vii84-90.
Title: Molecular detection of TP53, Ki-Ras and p16INK4A promoter methylation in plasma of patients with colorectal cancer and its association with prognosis. Results of a 3-year GOIM (Gruppo Oncologico dell'Italia Meridionale) prospective study.
Author: Bazan, V|Bruno, L|Augello, C|Agnese, V|Calo, V|Corsale, S|Gargano, G|Terrasi, M|Schiro, V|Di Fede, G|Adamo, V|Intrivici, C|Crosta, A|Rinaldi, G|Latteri, F|Dardanoni, G|Grassi, N|Valerio, M R|Colucci, G|Macaluso, M|Russo, A
PMID: 16760301
Journal: Toxicol Appl Pharmacol. 2006 Oct 1;216(1):89-97.
Title: Azidothymidine and cisplatin increase p14ARF expression in OVCAR-3 ovarian cancer cell line.
Author: Vaskivuo, Liisa|Rysa, Jaana|Koivupera, Johanna|Myllynen, Paivi|Vaskivuo, Tommi|Chvalova, Katerina|Serpi, Raisa|Savolainen, Eeva-Riitta|Puistola, Ulla|Vahakangas, Kirsi
PMID: 16797627
Journal: Genet Mol Res. 2006 Jun 30;5(2):315-22.
Title: Relationship of the methylenetetrahydrofolate reductase C677T polymorphism with microsatellite instability and promoter hypermethylation in sporadic colorectal cancer.
Author: Clarizia, Alessandra D|Bastos-Rodrigues, Luciana|Pena, Heloisa B|Anacleto, Charles|Rossi, Benedito|Soares, Fernando A|Lopes, Ademar|Rocha, Jose Claudio C|Caballero, Otavia|Camargo, Anamaria|Simpson, Andrew J G|Pena, Sergio D J
PMID: 16819711
Journal: Neoplasia. 2006 Jun;8(6):458-64.
Title: Combined analysis of COX-2 and p53 expressions reveals synergistic inverse correlations with microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Author: Ogino, Shuji|Brahmandam, Mohan|Kawasaki, Takako|Kirkner, Gregory J|Loda, Massimo|Fuchs, Charles S
PMID: 16820091
Journal: Oncol Rep. 2006 Aug;16(2):429-35.
Title: Promoter methylation status of the MGMT, hMLH1, and CDKN2A/p16 genes in non-neoplastic mucosa of patients with and without colorectal adenomas.
Author: Ye, Chuanzhong|Shrubsole, Martha J|Cai, Qiuyin|Ness, Reid|Grady, William M|Smalley, Walter|Cai, Hui|Washington, Kay|Zheng, Wei
PMID: 16820927
Journal: Oncogene. 2006 Oct 26;25(50):6582-94.
Title: Bak functionally complements for loss of Bax during p14ARF-induced mitochondrial apoptosis in human cancer cells.
Author: Hemmati, P G|Guner, D|Gillissen, B|Wendt, J|von Haefen, C|Chinnadurai, G|Dorken, B|Daniel, P T
PMID: 16847458
Journal: J Pathol. 2006 Oct;210(2):147-54.
Title: Down-regulation of p21 (CDKN1A/CIP1) is inversely associated with microsatellite instability and CpG island methylator phenotype (CIMP) in colorectal cancer.
Author: Ogino, S|Kawasaki, T|Kirkner, G J|Ogawa, A|Dorfman, I|Loda, M|Fuchs, C S
PMID: 16850502
Journal: J Gastroenterol Hepatol. 2006 Aug;21(8):1334-9.
Title: Influence of methylated p15 and p16 genes on clinicopathological features in colorectal cancer.
Author: Ishiguro, Atsushi|Takahata, Takenori|Saito, Masato|Yoshiya, Gen|Tamura, Yoshihiro|Sasaki, Mutsuo|Munakata, Akihiro
PMID: 16872319
Journal: J Pathol. 2006 Nov;210(3):344-50.
Title: Relationship between point gene mutation, chromosomal abnormality, and tumour suppressor gene methylation status in colorectal adenomas.
Author: Judson, H|Stewart, A|Leslie, A|Pratt, N R|Baty, D U|Steele, R J C|Carey, F A
PMID: 16902913
Journal: Head Neck. 2006 Oct;28(10):909-15.
Title: Phenotype-genotype correlation: challenge of intestinal-type adenocarcinoma of the nasal cavity and paranasal sinuses.
Author: Frattini, Milo|Perrone, Federica|Suardi, Simona|Balestra, Debora|Caramuta, Stefano|Colombo, Federica|Licitra, Lisa|Cantu, Giulio|Pierotti, Marco A|Pilotti, Silvana
PMID: 16906516
Journal: Dis Colon Rectum. 2006 Sep;49(9):1275-83.
Title: Colorectal mucinous adenocarcinoma: the clinicopathologic features and significance of p16 and p53 expression.
Author: King-Yin Lam, Alfred|Ong, Kate|Ho, Yik-Hong
PMID: 16912910
Journal: Am J Surg Pathol. 2006 Sep;30(9):1175-83.
Title: Correlation of pathologic features with CpG island methylator phenotype (CIMP) by quantitative DNA methylation analysis in colorectal carcinoma.
Author: Ogino, Shuji|Odze, Robert D|Kawasaki, Takako|Brahmandam, Mohan|Kirkner, Gregory J|Laird, Peter W|Loda, Massimo|Fuchs, Charles S
PMID: 16931963
Journal: Br J Cancer. 2006 Oct 23;95(8):1101-7.
Title: Genetic and epigenetic changes in primary metastatic and nonmetastatic colorectal cancer.
Author: Miranda, E|Destro, A|Malesci, A|Balladore, E|Bianchi, P|Baryshnikova, E|Franchi, G|Morenghi, E|Laghi, L|Gennari, L|Roncalli, M
PMID: 16969349
Journal: Int J Cancer. 2006 Nov 15;119(10):2272-8.
Title: APC gene methylation is inversely correlated with features of the CpG island methylator phenotype in colorectal cancer.
Author: Iacopetta, Barry|Grieu, Fabienne|Li, Wei|Ruszkiewicz, Andrew|Caruso, Maria|Moore, James|Watanabe, Goh|Kawakami, Kazuyuki
PMID: 16981189
Journal: Pol J Pathol. 2006;57(2):105-11.
Title: Correlation of microsatellite status, proliferation, apoptotic and selected immunohistochemical markers in colorectal carcinoma studied with tissue microarray.
Author: Okon, Krzysztof|Demczuk, Sergiusz|Klimkowska, Agnieszka|Wojcik, Piotr|Osuch, Czeslaw|Papla, Boleslaw|Stachura, Jerzy
PMID: 17019973
Journal: J Mol Diagn. 2006 Nov;8(5):582-8.
Title: CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: possible associations with male sex and KRAS mutations.
Author: Ogino, Shuji|Kawasaki, Takako|Kirkner, Gregory J|Loda, Massimo|Fuchs, Charles S
PMID: 17065427
Journal: World J Gastroenterol. 2006 Oct 21;12(39):6391-6.
Title: Aberrant cytological localization of p16 and CDK4 in colorectal epithelia in the normal adenoma carcinoma sequence.
Author: Zhao, Po|Mao, Xin|Talbot, Ian C
PMID: 17072968
Journal: Ann N Y Acad Sci. 2006 Sep;1075:185-90.
Title: Quantitative analysis of plasma DNA in colorectal cancer patients: a novel prognostic tool.
Author: Frattini, Milo|Gallino, Gianfrancesco|Signoroni, Stefano|Balestra, Debora|Battaglia, Luigi|Sozzi, Gabriella|Leo, Ermanno|Pilotti, Silvana|Pierotti, Marco A
PMID: 17108210
Journal: Ann N Y Acad Sci. 2006 Sep;1075:197-203.
Title: Comparative analysis of mesenteric and peripheral blood circulating tumor DNA in colorectal cancer patients.
Author: Taback, Bret|Saha, Sukamal|Hoon, Dave S B
PMID: 17108212
Journal: Praxis (Bern 1994). 2006 Nov 1;95(44):1709-12.
Title: [Pancreatic cancer].
Author: Schmid, R M
PMID: 17111879
Journal: Am J Surg Pathol. 2006 Dec;30(12):1491-501.
Title: Comparison of microsatellite instability, CpG island methylation phenotype, BRAF and KRAS status in serrated polyps and traditional adenomas indicates separate pathways to distinct colorectal carcinoma end points.
Author: O'Brien, Michael J|Yang, Shi|Mack, Charline|Xu, Huihong|Huang, Christopher S|Mulcahy, Elizabeth|Amorosino, Mark|Farraye, Francis A
PMID: 17122504
Journal: J Natl Cancer Inst. 2006 Dec 6;98(23):1731-8.
Title: Association of smoking, CpG island methylator phenotype, and V600E BRAF mutations in colon cancer.
Author: Samowitz, Wade S|Albertsen, Hans|Sweeney, Carol|Herrick, Jennifer|Caan, Bette J|Anderson, Kristin E|Wolff, Roger K|Slattery, Martha L
PMID: 17148775
Journal: Cell Oncol. 2006;28(5-6):247-57.
Title: Promoter methylation precedes chromosomal alterations in colorectal cancer development.
Author: Derks, Sarah|Postma, Cindy|Moerkerk, Peter T M|van den Bosch, Sandra M|Carvalho, Beatriz|Hermsen, Mario A J A|Giaretti, Walter|Herman, James G|Weijenberg, Matty P|de Bruine, Adriaan P|Meijer, Gerrit A|van Engeland, Manon
PMID: 17167178
Journal: Zhonghua Zhong Liu Za Zhi. 2006 Aug;28(8):564-7.
Title: [The effect of PKC-delta inhibitor Rottlerin on human colon cancer cell line SW1116 and its mechanism].
Author: Chen, Zhao-fei|Fang, Jing-yuan|Weng, Yu-rong|Sun, Dan-feng|Wang, Xia|Lu, Rong
PMID: 17236547
Journal: Oncology. 2006;71(5-6):437-45.
Title: The synergistic effect of 5-aza-2'-deoxycytidine and 5-fluorouracil on drug-resistant tumors.
Author: Morita, Shinji|Iida, Satoru|Kato, Keiji|Takagi, Yoko|Uetake, Hiroyuki|Sugihara, Kenichi
PMID: 17690560
Journal: Gut. 2007 Feb;56(2):215-26.
Title: Enhanced expression of hepatocyte growth factor activator inhibitor type 2-related small peptide at the invasive front of colon cancers.
Author: Uchiyama, S|Itoh, H|Naganuma, S|Nagaike, K|Fukushima, T|Tanaka, H|Hamasuna, R|Chijiiwa, K|Kataoka, H
PMID: 16809422
Journal: Mod Pathol. 2007 Jan;20(1):15-22. Epub 2006 Nov 3.
Title: Loss of nuclear p27 (CDKN1B/KIP1) in colorectal cancer is correlated with microsatellite instability and CIMP.
Author: Ogino, Shuji|Kawasaki, Takako|Kirkner, Gregory J|Yamaji, Taiki|Loda, Massimo|Fuchs, Charles S
PMID: 17086168
Journal: Gastroenterology. 2007 Jan;132(1):127-38.
Title: The CpG island methylator phenotype and chromosomal instability are inversely correlated in sporadic colorectal cancer.
Author: Goel, Ajay|Nagasaka, Takeshi|Arnold, Christian N|Inoue, Toru|Hamilton, Cody|Niedzwiecki, Donna|Compton, Carolyn|Mayer, Robert J|Goldberg, Richard|Bertagnolli, Monica M|Boland, C Richard
PMID: 17087942
Journal: Int J Cancer. 2007 Feb 1;120(3):656-63.
Title: Diet and lifestyle factor associations with CpG island methylator phenotype and BRAF mutations in colon cancer.
Author: Slattery, Martha L|Curtin, Karen|Sweeney, Carol|Levin, Theodore R|Potter, John|Wolff, Roger K|Albertsen, Hans|Samowitz, Wade S
PMID: 17096326
Journal: Ann Surg Oncol. 2007 May;14(5):1752-62.
Title: Effect of combined therapy with low-dose 5-aza-2'-deoxycytidine and irinotecan on colon cancer cell line HCT-15.
Author: Ishiguro, Megumi|Iida, Satoru|Uetake, Hiroyuki|Morita, Shinji|Makino, Hiroshi|Kato, Keiji|Takagi, Yoko|Enomoto, Masayuki|Sugihara, Kenichi
PMID: 17195906
Journal: Hum Pathol. 2007 Apr;38(4):585-92. Epub 2007 Jan 19.
Title: Cytoplasmic localization of p27 (cyclin-dependent kinase inhibitor 1B/KIP1) in colorectal cancer: inverse correlations with nuclear p27 loss, microsatellite instability, and CpG island methylator phenotype.
Author: Ogino, Shuji|Kawasaki, Takako|Ogawa, Akiyo|Kirkner, Gregory J|Loda, Massimo|Fuchs, Charles S
PMID: 17239930
Journal: Oncogene. 2007 Jun 28;26(30):4435-41. Epub 2007 Jan 29.
Title: Promoter methylation of the mutated in colorectal cancer gene is a frequent early event in colorectal cancer.
Author: Kohonen-Corish, M R J|Sigglekow, N D|Susanto, J|Chapuis, P H|Bokey, E L|Dent, O F|Chan, C|Lin, B P C|Seng, T J|Laird, P W|Young, J|Leggett, B A|Jass, J R|Sutherland, R L
PMID: 17260021
Journal: Hum Pathol. 2007 Apr;38(4):614-20. Epub 2007 Jan 31.
Title: TGFBR2 mutation is correlated with CpG island methylator phenotype in microsatellite instability-high colorectal cancer.
Author: Ogino, Shuji|Kawasaki, Takako|Ogawa, Akiyo|Kirkner, Gregory J|Loda, Massimo|Fuchs, Charles S
PMID: 17270239
Journal: Int J Cancer. 2007 May 1;120(9):1922-9.
Title: Evidence for the role of aberrant DNA methylation in the pathogenesis of Lynch syndrome adenomas.
Author: Kaz, Andrew|Kim, Young-Ho|Dzieciatkowski, Slavomir|Lynch, Henry|Watson, Patrice|Kay Washington, Mary|Lin, Li|Grady, William M
PMID: 17278092
Journal: J Biol Chem. 2007 Apr 20;282(16):12249-59. Epub 2007 Feb 16.
Title: Inhibition of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway decreases DNA methylation in colon cancer cells.
Author: Lu, Rong|Wang, Xia|Chen, Zhao-Fei|Sun, Dan-Feng|Tian, Xiao-Qing|Fang, Jing-Yuan
PMID: 17307743
Journal: Gut. 2007 Nov;56(11):1564-71. Epub 2007 Mar 5.
Title: Molecular correlates with MGMT promoter methylation and silencing support CpG island methylator phenotype-low (CIMP-low) in colorectal cancer.
Author: Ogino, Shuji|Kawasaki, Takako|Kirkner, Gregory J|Suemoto, Yuko|Meyerhardt, Jeffrey A|Fuchs, Charles S
PMID: 17339237
Journal: Hum Pathol. 2007 Jun;38(6):842-9. Epub 2007 Mar 12.
Title: Fatty acid synthase overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype.
Author: Ogino, Shuji|Kawasaki, Takako|Ogawa, Akiyo|Kirkner, Gregory J|Loda, Massimo|Fuchs, Charles S
PMID: 17350669
Journal: Virchows Arch. 2007 May;450(5):529-37. Epub 2007 Mar 20.
Title: CpG island methylation, response to combination chemotherapy, and patient survival in advanced microsatellite stable colorectal carcinoma.
Author: Ogino, Shuji|Meyerhardt, Jeffrey A|Kawasaki, Takako|Clark, Jeffrey W|Ryan, David P|Kulke, Matthew H|Enzinger, Peter C|Wolpin, Brian M|Loda, Massimo|Fuchs, Charles S
PMID: 17372756
Journal: Dig Dis Sci. 2007 Sep;52(9):2305-11.
Title: Expression of peroxisome proliferator-activated receptor-gamma in colon cancer: correlation with histopathological parameters, cell cycle-related molecules, and patients' survival.
Author: Theocharis, Stamatios|Giaginis, Costas|Parasi, Aikaterini|Margeli, Alexandra|Kakisis, John|Agapitos, Emmanuel|Kouraklis, Gregorios
PMID: 17393321
Journal: Gastroenterology. 2007 Apr;132(4):1254-60. Epub 2007 Jan 25.
Title: Rare CpG island methylator phenotype in ulcerative colitis-associated neoplasias.
Author: Konishi, Kazuo|Shen, Lanlan|Wang, Suna|Meltzer, Stephen J|Harpaz, Noam|Issa, Jean-Pierre J
PMID: 17408633
Journal: Carcinogenesis. 2007 Aug;28(8):1672-9. Epub 2007 Apr 21.
Title: Genetic polymorphisms in one-carbon metabolism: associations with CpG island methylator phenotype (CIMP) in colon cancer and the modifying effects of diet.
Author: Curtin, Karen|Slattery, Martha L|Ulrich, Cornelia M|Bigler, Jeannette|Levin, Theodore R|Wolff, Roger K|Albertsen, Hans|Potter, John D|Samowitz, Wade S
PMID: 17449906
Journal: World J Gastroenterol. 2007 Feb 28;13(8):1187-94.
Title: Comethylation of p16 and MGMT genes in colorectal carcinoma: correlation with clinicopathological features and prognostic value.
Author: Krtolica, Koviljka|Krajnovic, Milena|Usaj-Knezevic, Slavica|Babic, Dragan|Jovanovic, Dusan|Dimitrijevic, Bogomir
PMID: 17451198
Journal: Orv Hetil. 2007 Apr 29;148(17):779-85.
Title: [Stem cell theory of colorectal cancer and its connection with molecular-biological data].
Author: Hagymasi, Krisztina|Molnar, Bela|Sipos, Ferenc|Galamb, Orsolya|Tulassay, Zsolt
PMID: 17452307
Journal: World J Gastroenterol. 2007 Mar 14;13(10):1528-33.
Title: Stool-based DNA testing, a new noninvasive method for colorectal cancer screening, the first report from Iran.
Author: Abbaszadegan, Mohammad Reza|Tavasoli, Alireza|Velayati, Arash|Sima, Hamid Reza|Vosooghinia, Hassan|Farzadnia, Mehdi|Asadzedeh, Hamid|Gholamin, Mehran|Dadkhah, Ezzat|Aarabi, Azadeh
PMID: 17461444
Journal: Anticancer Res. 2007 Mar-Apr;27(2):1151-6.
Title: Lower specific micronutrient intake in colorectal cancer patients with tumors presenting promoter hypermethylation in p16(INK4a), p4(ARF) and hMLH1.
Author: Mas, Sergi|Lafuente, M Jose|Crescenti, Anna|Trias, Manuel|Ballesta, Antonio|Molina, Rafael|Zheng, Shichun|Wiencke, John K|Lafuente, Amalia
PMID: 17465256
Journal: BMC Cancer. 2007 May 2;7:72.
Title: 18q loss of heterozygosity in microsatellite stable colorectal cancer is correlated with CpG island methylator phenotype-negative (CIMP-0) and inversely with CIMP-low and CIMP-high.
Author: Ogino, Shuji|Kawasaki, Takako|Kirkner, Gregory J|Ohnishi, Mutsuko|Fuchs, Charles S
PMID: 17474983
Journal: Oncogene. 2007 Oct 18;26(48):6954-8. Epub 2007 May 7.
Title: p21(Waf1/Cip1/Sdi1) mediates retinoblastoma protein degradation.
Author: Broude, E V|Swift, M E|Vivo, C|Chang, B-D|Davis, B M|Kalurupalle, S|Blagosklonny, M V|Roninson, I B
PMID: 17486059
Journal: Cell Cycle. 2007 Jun 1;6(11):1293-7. Epub 2007 Jun 19.
Title: CDK4 inhibitors and apoptosis: a novel mechanism requiring nucleolar targeting of RelA.
Author: Thoms, Hazel C|Dunlop, Malcolm G|Stark, Lesley A
PMID: 17525529
Journal: Int J Clin Pract. 2007 Sep;61(9):1523-9.
Title: Relationship between expression and methylation status of p16INK4a and the proliferative activity of different areas' tumour cells in human colorectal cancer.
Author: Jie, G|Zhixiang, S|Lei, S|Hesheng, L|Xiaojun, T
PMID: 17537196
Journal: J Mol Diagn. 2007 Jul;9(3):305-14.
Title: Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample.
Author: Ogino, Shuji|Kawasaki, Takako|Kirkner, Gregory J|Kraft, Peter|Loda, Massimo|Fuchs, Charles S
PMID: 17591929
Journal: Anticancer Res. 2007 May-Jun;27(3B):1459-63.
Title: A highly sensitive method for the detection of p16 methylation in the serum of colorectal cancer patients.
Author: Nakayama, Goro|Hibi, Kenji|Nakayama, Hiroshi|Kodera, Yasuhiro|Ito, Katsuki|Akiyama, Seiji|Nakao, Akimasa
PMID: 17595762
Journal: Clin Cancer Res. 2007 Jul 1;13(13):3831-9.
Title: Reduced likelihood of metastases in patients with microsatellite-unstable colorectal cancer.
Author: Malesci, Alberto|Laghi, Luigi|Bianchi, Paolo|Delconte, Gabriele|Randolph, Ann|Torri, Valter|Carnaghi, Carlo|Doci, Roberto|Rosati, Riccardo|Montorsi, Marco|Roncalli, Massimo|Gennari, Leandro|Santoro, Armando
PMID: 17606714
Journal: Carcinogenesis. 2007 Sep;28(9):1985-90. Epub 2007 Jul 9.
Title: MGMT germline polymorphism is associated with somatic MGMT promoter methylation and gene silencing in colorectal cancer.
Author: Ogino, Shuji|Hazra, Aditi|Tranah, Gregory J|Kirkner, Gregory J|Kawasaki, Takako|Nosho, Katsuhiko|Ohnishi, Mutsuko|Suemoto, Yuko|Meyerhardt, Jeffrey A|Hunter, David J|Fuchs, Charles S
PMID: 17621591
Journal: Cancer Sci. 2007 Sep;98(9):1454-60.
Title: Methylation levels of LINE-1 repeats and CpG island loci are inversely related in normal colonic mucosa.
Author: Iacopetta, Barry|Grieu, Fabienne|Phillips, Michael|Ruszkiewicz, Andrew|Moore, James|Minamoto, Toshinari|Kawakami, Kazuyuki
PMID: 17640302
Journal: Cell Oncol. 2007;29(4):301-13.
Title: Cell-cycle and apoptosis regulators (p16INK4A, p21CIP1, beta-catenin, survivin, and hTERT) and morphometry-defined MPECs predict metachronous cancer development in colorectal adenoma patients.
Author: Soreide, Kjetil|Buter, Tirza C E|Janssen, Emiel A|Gudlaugsson, Einar|Skaland, Ivar|Korner, Hartwig|Baak, Jan P A
PMID: 17641414
Journal: Zhonghua Yi Xue Za Zhi. 2007 Apr 10;87(14):982-6.
Title: [Effects of extracellular signal-regulated kinase/mitogen-activated protein kinase signaling pathway activation on proliferation and cell cycle associated genes in human colon cancer cells].
Author: Wang, Xia|Lu, Rong|Fang, Jing-yuan
PMID: 17650425
Journal: Am J Physiol Gastrointest Liver Physiol. 2007 Oct;293(4):G758-72. Epub 2007 Jul
Title: Nuclear expression of E2F4 induces cell death via multiple pathways in normal human intestinal epithelial crypt cells but not in colon cancer cells.
Author: Garneau, Hugo|Alvarez, Laetitia|Paquin, Marie-Christine|Lussier, Carine|Rancourt, Claudine|Tremblay, Eric|Beaulieu, Jean-Francois|Rivard, Nathalie
PMID: 17656449
Journal: Int J Cancer. 2007 Nov 15;121(10):2192-7.
Title: Association of the SUV39H1 histone methyltransferase with the DNA methyltransferase 1 at mRNA expression level in primary colorectal cancer.
Author: Kang, Mi Yeon|Lee, Bo Bin|Kim, Young-Ho|Chang, Dong Kyoung|Kyu Park, Seo|Chun, Ho-Kyung|Song, Sang Yong|Park, Joobae|Kim, Duk-Hwan
PMID: 17657744
Journal: Int J Biochem Cell Biol. 2007;39(12):2215-25.
Title: Effects of folate cycle disruption by the green tea polyphenol epigallocatechin-3-gallate.
Author: Navarro-Peran, Enma|Cabezas-Herrera, Juan|Campo, Luis Sanchez Del|Rodriguez-Lopez, Jose Neptuno
PMID: 17683969
Journal: Neoplasia. 2007 Jul;9(7):569-77.
Title: Correlation of beta-catenin localization with cyclooxygenase-2 expression and CpG island methylator phenotype (CIMP) in colorectal cancer.
Author: Kawasaki, Takako|Nosho, Katsuhiko|Ohnishi, Mutsuko|Suemoto, Yuko|Kirkner, Gregory J|Dehari, Reiko|Meyerhardt, Jeffrey A|Fuchs, Charles S|Ogino, Shuji
PMID: 17710160
Journal: Cancer Sci. 2007 Nov;98(11):1809-16. Epub 2007 Sep 2.
Title: Identification of JTP-70902, a p15(INK4b)-inductive compound, as a novel MEK1/2 inhibitor.
Author: Yamaguchi, Takayuki|Yoshida, Takayuki|Kurachi, Reina|Kakegawa, Junya|Hori, Yoshikazu|Nanayama, Toyomichi|Hayakawa, Kazuhide|Abe, Hiroyuki|Takagi, Koichi|Matsuzaki, Youichirou|Koyama, Makoto|Yogosawa, Shingo|Sowa, Yoshihiro|Yamori, Takao|Tajima, Nobuyuki|S
PMID: 17784872
Journal: Clin Cancer Res. 2007 Oct 15;13(20):6093-8.
Title: Association between DNA methylation and shortened survival in patients with advanced colorectal cancer treated with 5-fluorouracil based chemotherapy.
Author: Shen, Lanlan|Catalano, Paul J|Benson, Al B 3rd|O'Dwyer, Peter|Hamilton, Stanley R|Issa, Jean-Pierre J
PMID: 17947473
Journal: Anticancer Res. 2007 Sep-Oct;27(5A):3367-70.
Title: P16 methylation in serum as a potential marker for the malignancy of colorectal carcinoma.
Author: Nakayama, Goro|Hibi, Kenji|Kodera, Yasuhiro|Koike, Masahiko|Fujiwara, Michitaka|Nakao, Akimasa
PMID: 17970082
Journal: Cytogenet Genome Res. 2007;118(2-4):214-21.
Title: SNP-Array genotyping and spectral karyotyping reveal uniparental disomy as early mutational event in MSS- and MSI-colorectal cancer cell lines.
Author: Melcher, R|Al-Taie, O|Kudlich, T|Hartmann, E|Maisch, S|Steinlein, C|Schmid, M|Rosenwald, A|Menzel, T|Scheppach, W|Luhrs, H
PMID: 18000373
Journal: Gastroenterol Hepatol. 2007 Dec;30(10):592-6.
Title: [Genetic profile and molecular bases of pancreatic carcinogenesis].
Author: Sanchez-Fayos Calabuig, Paloma|Martin Relloso, Maria Jesus|Porres Cubero, Juan Carlos
PMID: 18028855
Journal: J Nutr. 2007 Dec;137(12):2622-8.
Title: Annurca apple polyphenols have potent demethylating activity and can reactivate silenced tumor suppressor genes in colorectal cancer cells.
Author: Fini, Lucia|Selgrad, Michael|Fogliano, Vincenzo|Graziani, Giulia|Romano, Marco|Hotchkiss, Erin|Daoud, Yahya A|De Vol, Edward B|Boland, C Richard|Ricciardiello, Luigi
PMID: 18029474
Journal: Neoplasia. 2007 Dec;9(12):1091-8.
Title: IGFBP3 promoter methylation in colorectal cancer: relationship with microsatellite instability, CpG island methylator phenotype, and p53.
Author: Kawasaki, Takako|Nosho, Katsuhiko|Ohnishi, Mutsuko|Suemoto, Yuko|Kirkner, Gregory J|Fuchs, Charles S|Ogino, Shuji
PMID: 18084616
Journal: J Exp Clin Cancer Res. 2007 Dec;26(4):521-6.
Title: Promoter hypermethylation of tumor-related genes in sporadic colorectal cancer in young patients.
Author: Noda, H|Mashima, R|Kamiyama, H|Okada, S|Kawamura, Y J|Konishi, F
PMID: 18365548
Journal: Hered Cancer Clin Pract. 2007 Jun 15;5(2):97-116.
Title: Some molecular and clinical aspects of genetic predisposition to malignant melanoma and tumours of various site of origin.
Author: Debniak, Tadeusz
PMID: 19725989
Journal: J Nutr Biochem. 2008 May;19(5):328-35.
Title: Moderate folate depletion modulates the expression of selected genes involved in cell cycle, intracellular signaling and folate uptake in human colonic epithelial cell lines.
Author: Crott, Jimmy W|Liu, Zhenhua|Keyes, Mary K|Choi, Sang-Woon|Jang, Hyeran|Moyer, Mary P|Mason, Joel B
PMID: 17681772
Journal: Dig Dis Sci. 2008 May;53(5):1289-96.
Title: Prognostic and predictive value of thymidylate synthase expression in colon cancer.
Author: Tsourouflis, Gerasimos|Theocharis, Stamatios E|Sampani, Anastasia|Giagini, Athina|Kostakis, Alkiviadis|Kouraklis, Gregory
PMID: 17934851
Journal: Carcinogenesis. 2008 Feb;29(2):434-9.
Title: Integrated analysis of chromosomal, microsatellite and epigenetic instability in colorectal cancer identifies specific associations between promoter methylation of pivotal tumour suppressor and DNA repair genes and specific chromosomal alterations.
Author: Derks, Sarah|Postma, Cindy|Carvalho, Beatriz|van den Bosch, Sandra M|Moerkerk, Peter T M|Herman, James G|Weijenberg, Matty P|de Bruine, Adriaan P|Meijer, Gerrit A|van Engeland, Manon
PMID: 18048385
Journal: Mod Pathol. 2008 Feb;21(2):150-8. Epub 2007 Dec 14.
Title: WRN promoter methylation possibly connects mucinous differentiation, microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Author: Kawasaki, Takako|Ohnishi, Mutsuko|Suemoto, Yuko|Kirkner, Gregory J|Liu, Zhiqian|Yamamoto, Hiroyuki|Loda, Massimo|Fuchs, Charles S|Ogino, Shuji
PMID: 18084250
Journal: Clin Cancer Res. 2008 Jan 1;14(1):48-54.
Title: Aberrant crypt foci as precursors of the dysplasia-carcinoma sequence in patients with ulcerative colitis.
Author: Kukitsu, Takehiro|Takayama, Tetsuji|Miyanishi, Koji|Nobuoka, Atsushi|Katsuki, Shinichi|Sato, Yasushi|Takimoto, Rishu|Matsunaga, Takuya|Kato, Junji|Sonoda, Tomoko|Sakamaki, Sumio|Niitsu, Yoshiro
PMID: 18172251
Journal: Int J Colorectal Dis. 2008 Apr;23(4):389-400.
Title: Metachronous cancer development in patients with sporadic colorectal adenomas-multivariate risk model with independent and combined value of hTERT and survivin.
Author: Soreide, Kjetil|Gudlaugsson, Einar|Skaland, Ivar|Janssen, Emiel A M|Van Diermen, Bianca|Korner, Hartwig|Baak, Jan P A
PMID: 18189140
Journal: Mod Pathol. 2008 Mar;21(3):245-55.
Title: CpG island methylator phenotype-low (CIMP-low) colorectal cancer shows not only few methylated CIMP-high-specific CpG islands, but also low-level methylation at individual loci.
Author: Kawasaki, Takako|Ohnishi, Mutsuko|Nosho, Katsuhiko|Suemoto, Yuko|Kirkner, Gregory J|Meyerhardt, Jeffrey A|Fuchs, Charles S|Ogino, Shuji
PMID: 18204436
Journal: Cancer Sci. 2008 Feb;99(2):253-9.
Title: Aberrant methylation status of known methylation-sensitive CpG islands in gastrointestinal stromal tumors without any correlation to the state of c-kit and PDGFRA gene mutations and their malignancy.
Author: Saito, Kana|Sakurai, Shinji|Sano, Takaaki|Sakamoto, Kazuha|Asao, Takayuki|Hosoya, Yoshinori|Nakajima, Takashi|Kuwano, Hiroyuki
PMID: 18271923
Journal: Hum Pathol. 2008 Apr;39(4):599-604.
Title: Aurora kinase expression in colorectal adenocarcinoma: correlations with clinicopathological features, p16 expression, and telomerase activity.
Author: Lam, Alfred King-Yin|Ong, Kate|Ho, Yik-Hong
PMID: 18284933
Journal: Dig Dis Sci. 2008 Oct;53(10):2723-31.
Title: Sporadic colon cancer: mismatch repair immunohistochemistry and microsatellite instability in Omani subjects.
Author: Ashktorab, Hassan|Brim, Hassan|Al-Riyami, Marwa|Date, Anand|Al-Mawaly, Kamla|Kashoub, Masoud|Al-Mjeni, Rayhaneh|Smoot, Duane T|Al-Moundhri, Mansoor|Al-Hashemi, Suleiman|Ganguly, Shyam S|Raeburn, Sandy
PMID: 18299982
Journal: Cancer. 2008 Apr 15;112(8):1699-707.
Title: Association of interindividual differences in p14ARF promoter methylation with single nucleotide polymorphism in primary colorectal cancer.
Author: Kang, Mi Yeon|Lee, Bo Bin|Ji, Yong Ick|Jung, Eun Hyun|Chun, Ho-Kyung|Song, Sang Yong|Park, Seong-Eun|Park, Joobae|Kim, Duk-Hwan
PMID: 18327804
Journal: Mol Cell Biol. 2008 May;28(10):3219-35.
Title: Histone deacetylase inhibitor depsipeptide activates silenced genes through decreasing both CpG and H3K9 methylation on the promoter.
Author: Wu, Li-Peng|Wang, Xi|Li, Lian|Zhao, Ying|Lu, Shaoli|Yu, Yu|Zhou, Wen|Liu, Xiangyu|Yang, Jing|Zheng, Zhixin|Zhang, Hui|Feng, Jingnan|Yang, Yang|Wang, Haiying|Zhu, Wei-Guo
PMID: 18332107
Journal: Digestion. 2008;77(1):48-56.
Title: Malignant transformation of normal enterocytes following downregulation of Bak expression.
Author: Liberman, Eliezer|Naumov, Inna|Kazanov, Diana|Dvory-Sobol, Hadas|Sagiv, Eyal|Birkenfeld, Shlomo|Deutsch, Varda|Trakhtenbrot, Luba|Moshkowitz, Menachem|Arber, Nadir
PMID: 18349538
Journal: Int J Cancer. 2008 Jun 15;122(12):2767-73.
Title: LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Author: Ogino, Shuji|Kawasaki, Takako|Nosho, Katsuhiko|Ohnishi, Mutsuko|Suemoto, Yuko|Kirkner, Gregory J|Fuchs, Charles S
PMID: 18366060
Journal: Cancer Lett. 2008 May 18;263(2):170-81.
Title: Quantitative and qualitative characterization of plasma DNA identifies primary and recurrent colorectal cancer.
Author: Frattini, M|Gallino, G|Signoroni, S|Balestra, D|Lusa, L|Battaglia, L|Sozzi, G|Bertario, L|Leo, E|Pilotti, S|Pierotti, M A
PMID: 18395974
Journal: Mol Med. 2008 Jul-Aug;14(7-8):412-21.
Title: p16INK4a gene promoter hypermethylation in mucosa as a prognostic factor for patients with colorectal cancer.
Author: Wettergren, Yvonne|Odin, Elisabeth|Nilsson, Staffan|Carlsson, Goran|Gustavsson, Bengt
PMID: 18418463
Journal: J Korean Med Sci. 2008 Apr;23(2):270-7.
Title: CpG island methylation in familial colorectal cancer patients not fulfilling the Amsterdam criteria.
Author: Kim, Hee Cheol|Lee, Hyeon Jung|Roh, Seon Ae|Kim, Jung-Sun|Yu, Chang Sik|Kim, Jin Cheon
PMID: 18437011
Journal: J Cell Biochem. 2008 Aug 15;104(6):2228-40.
Title: Inactivation of the p19(ARF) tumor suppressor affects intestinal epithelial cell proliferation and integrity.
Author: Farmer, Tiffany E|Williams, Christopher S|Washington, M Kay|Hiebert, Scott W
PMID: 18442038
Journal: Clin Cancer Res. 2008 May 1;14(9):2560-9.
Title: Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma.
Author: Suehiro, Yutaka|Wong, Chi Wai|Chirieac, Lucian R|Kondo, Yutaka|Shen, Lanlan|Webb, C Renee|Chan, Yee Wai|Chan, Annie S Y|Chan, Tsun Leung|Wu, Tsung-Teh|Rashid, Asif|Hamanaka, Yuichiro|Hinoda, Yuji|Shannon, Rhonda L|Wang, Xuemei|Morris, Jeffrey|Issa, Jean-P
PMID: 18451217
Journal: Fam Cancer. 2008;7(4):331-7.
Title: Higher occurrence of childhood cancer in families with germline mutations in BRCA2, MMR and CDKN2A genes.
Author: Magnusson, Susanne|Borg, Ake|Kristoffersson, Ulf|Nilbert, Mef|Wiebe, Thomas|Olsson, Hakan
PMID: 18481196
Journal: Neoplasia. 2008 Jun;10(6):534-41.
Title: PIK3CA mutation in colorectal cancer: relationship with genetic and epigenetic alterations.
Author: Nosho, Katsuhiko|Kawasaki, Takako|Ohnishi, Mutsuko|Suemoto, Yuko|Kirkner, Gregory J|Zepf, Dimity|Yan, Liying|Longtine, Janina A|Fuchs, Charles S|Ogino, Shuji
PMID: 18516290
Journal: Mol Cancer Ther. 2008 Jun;7(6):1337-46.
Title: In vitro differential sensitivity of melanomas to phenothiazines is based on the presence of codon 600 BRAF mutation.
Author: Ikediobi, Ogechi N|Reimers, Mark|Durinck, Steffen|Blower, Paul E|Futreal, Andrew P|Stratton, Michael R|Weinstein, John N
PMID: 18524847
Journal: Br J Cancer. 2008 Jul 8;99(1):136-42.
Title: Profiling CpG island field methylation in both morphologically normal and neoplastic human colonic mucosa.
Author: Belshaw, N J|Elliott, G O|Foxall, R J|Dainty, J R|Pal, N|Coupe, A|Garg, D|Bradburn, D M|Mathers, J C|Johnson, I T
PMID: 18542073
Journal: World J Gastroenterol. 2008 Jun 21;14(23):3662-71.
Title: Methylenetetrahydrofolate reductase C677T genotype affects promoter methylation of tumor-specific genes in sporadic colorectal cancer through an interaction with folate/vitamin B12 status.
Author: Mokarram, Pooneh|Naghibalhossaini, Fakhraddin|Saberi Firoozi, Mehdi|Hosseini, Seyed Vahid|Izadpanah, Ahmad|Salahi, Heshmetalah|Malek-Hosseini, Seyed Ali|Talei, Abdoulrasool|Mojallal, Mehra
PMID: 18595133
Journal: Dis Colon Rectum. 2008 Sep;51(9):1395-402.
Title: MDM2 mRNA expression in the p53 pathway may predict the potential of invasion and liver metastasis in colorectal cancer.
Author: Kondo, Ito|Iida, Satoru|Takagi, Yoko|Sugihara, Kenichi
PMID: 18607552
Journal: Genes Chromosomes Cancer. 2008 Oct;47(10):835-44.
Title: The MLH1 -93 G>A promoter polymorphism and genetic and epigenetic alterations in colon cancer.
Author: Samowitz, Wade S|Curtin, Karen|Wolff, Roger K|Albertsen, Hans|Sweeney, Carol|Caan, Bette J|Ulrich, Cornelia M|Potter, John D|Slattery, Martha L
PMID: 18615680
Journal: Chem Biol Interact. 2008 Aug 11;174(3):201-10.
Title: Inhibition of cell-cycle progression in human colorectal carcinoma Lovo cells by andrographolide.
Author: Shi, Ming-Der|Lin, Hui-Hsuan|Lee, Yi-Che|Chao, Jian-Kang|Lin, Rong-An|Chen, Jing-Hsien
PMID: 18619950
Journal: Int J Oncol. 2008 Aug;33(2):351-60.
Title: Changes in expression of imprinted genes following treatment of human cancer cell lines with non-mutagenic or mutagenic carcinogens.
Author: Shibui, Takeo|Higo, Yukari|Tsutsui, Takeo W|Uchida, Minoru|Oshimura, Mitsuo|Barrett, J Carl|Tsutsui, Takeki
PMID: 18636156
Journal: Int J Cancer. 2008 Oct 1;123(7):1556-64.
Title: Molecular characteristics and predictors of survival in patients with malignant neuroendocrine tumors.
Author: Arnold, Christian N|Nagasaka, Takeshi|Goel, Ajay|Scharf, Iris|Grabowski, Patricia|Sosnowski, Andrea|Schmitt-Graff, Annette|Boland, C Richard|Arnold, Rudolf|Blum, Hubert E
PMID: 18646189
Journal: Carcinogenesis. 2008 Nov;29(11):2089-95.
Title: S-adenosylhomocysteine hydrolase downregulation contributes to tumorigenesis.
Author: Leal, J F|Ferrer, I|Blanco-Aparicio, C|Hernandez-Losa, J|Ramon Y Cajal, S|Carnero, A|Lleonart, M E
PMID: 18713839
Journal: Pathology. 2008 Oct;40(6):580-5.
Title: p16 expression in colorectal adenocarcinoma: marker of aggressiveness and morphological types.
Author: Lam, Alfred King-Yin|Ong, Kate|Giv, Mahmoud Jafari|Ho, Yik-Hong
PMID: 18752124
Journal: Int J Cancer. 2008 Dec 1;123(11):2626-31.
Title: Characterization of humoral immune responses against p16, p53, HPV16 E6 and HPV16 E7 in patients with HPV-associated cancers.
Author: Reuschenbach, Miriam|Waterboer, Tim|Wallin, Keng-Ling|Einenkel, Jens|Dillner, Joakim|Hamsikova, Eva|Eschenbach, Denise|Zimmer, Heike|Heilig, Bernhard|Kopitz, Jurgen|Pawlita, Michael|Doeberitz, Magnus von Knebel|Wentzensen, Nicolas
PMID: 18785210
Journal: Cancer Res. 2008 Sep 15;68(18):7258-63.
Title: Kaiso contributes to DNA methylation-dependent silencing of tumor suppressor genes in colon cancer cell lines.
Author: Lopes, Eloisi C|Valls, Ester|Figueroa, Maria E|Mazur, Alexander|Meng, Fan-Guo|Chiosis, Gabriela|Laird, Peter W|Schreiber-Agus, Nicole|Greally, John M|Prokhortchouk, Egor|Melnick, Ari
PMID: 18794111
Journal: Int J Oncol. 2008 Oct;33(4):767-76.
Title: Histone deacetylase inhibitor scriptaid induces cell cycle arrest and epigenetic change in colon cancer cells.
Author: Lee, Eun Ju|Lee, Bo Bin|Kim, Soon-Ja|Park, Yong-Doo|Park, Joobae|Kim, Duk-Hwan
PMID: 18813790
Journal: Oncol Rep. 2008 Oct;20(4):921-7.
Title: DNA methylotype analysis in colorectal cancer.
Author: Yu, Jinsheng|Freimuth, Robert R|Culverhouse, Robert|Marsh, Sharon|Watson, Mark A|McLeod, Howard L
PMID: 18813836
Journal: Med Sci Monit. 2008 Oct;14(10):BR219-25.
Title: Methylation of the MGMT and p16 genes in sporadic colorectal carcinoma and corresponding normal colonic mucosa.
Author: Krakowczyk, Lukasz|Strzelczyk, Joanna K|Adamek, Brygida|Zalewska-Ziob, Marzena|Arendt, Jerzy|Poltorak, Stanislaw|Maciejewski, Boguslaw|Wiczkowski, Andrzej
PMID: 18830187
Journal: Arch Pathol Lab Med. 2008 Oct;132(10):1657-65.
Title: CpG island methylator phenotype in colorectal cancers: comparison of the new and classic CpG island methylator phenotype marker panels.
Author: Lee, Sun|Cho, Nam-Yun|Yoo, Eun Joo|Kim, Jung Ho|Kang, Gyeong Hoon
PMID: 18834226
Journal: Cancer Res. 2008 Oct 15;68(20):8541-6.
Title: Hypermethylator phenotype in sporadic colon cancer: study on a population-based series of 582 cases.
Author: Barault, Ludovic|Charon-Barra, Celine|Jooste, Valerie|de la Vega, Mathilde Funes|Martin, Laurent|Roignot, Patrick|Rat, Patrick|Bouvier, Anne-Marie|Laurent-Puig, Pierre|Faivre, Jean|Chapusot, Caroline|Piard, Francoise
PMID: 18922929
Journal: Nucleic Acids Res. 2008 Nov;36(20):6535-47.
Title: Whole genome exon arrays identify differential expression of alternatively spliced, cancer-related genes in lung cancer.
Author: Xi, Liqiang|Feber, Andrew|Gupta, Vanita|Wu, Maoxin|Bergemann, Andrew D|Landreneau, Rodney J|Litle, Virginia R|Pennathur, Arjun|Luketich, James D|Godfrey, Tony E
PMID: 18927117
Journal: Pathobiology. 2008;75(5):281-7.
Title: MBD2-mediated transcriptional repression of the p14ARF tumor suppressor gene in human colon cancer cells.
Author: Martin, Valerie|Jorgensen, Helle F|Chaubert, Audrey S Baur|Berger, Jennifer|Barr, Helen|Shaw, Phillip|Bird, Adrian|Chaubert, Pascal
PMID: 18931530
Journal: Z Gastroenterol. 2008 Oct;46(10):1202-6.
Title: [Epigenetic alterations in colorectal carcinomas and precancerous lesions].
Author: Tischoff, I|Tannapfel, A
PMID: 18937191
Journal: Eur J Cancer. 2008 Nov;44(17):2689-95.
Title: Epigenetic events in normal colonic mucosa surrounding colorectal cancer lesions.
Author: Ramirez, N|Bandres, E|Navarro, A|Pons, A|Jansa, S|Moreno, I|Martinez-Rodenas, F|Zarate, R|Bitarte, N|Monzo, M|Garcia-Foncillas, J
PMID: 18938072
Journal: Histopathology. 2008 Nov;53(5):588-98.
Title: Cyclin D1 is frequently overexpressed in microsatellite unstable colorectal cancer, independent of CpG island methylator phenotype.
Author: Nosho, K|Kawasaki, T|Chan, A T|Ohnishi, M|Suemoto, Y|Kirkner, G J|Fuchs, C S|Ogino, S
PMID: 18983468
Journal: PLoS One. 2008;3(11):e3698.
Title: Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample.
Author: Nosho, Katsuhiko|Irahara, Natsumi|Shima, Kaori|Kure, Shoko|Kirkner, Gregory J|Schernhammer, Eva S|Hazra, Aditi|Hunter, David J|Quackenbush, John|Spiegelman, Donna|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji
PMID: 19002263
Journal: Zhonghua Yi Xue Za Zhi. 2008 Jul 29;88(29):2025-9.
Title: [Clinicopathological significance of expressions of DNA dependent protein kinase catalytic subunit and P16 in colorectal carcinoma].
Author: Lu, Yang|Zhang, Hong-lin|Li, Ya-zhuo|Zhao, Po
PMID: 19080428
Journal: Mol Cancer. 2008 Dec 31;7:94.
Title: Gene methylation profiles of normal mucosa, and benign and malignant colorectal tumors identify early onset markers.
Author: Ahlquist, Terje|Lind, Guro E|Costa, Vera L|Meling, Gunn I|Vatn, Morten|Hoff, Geir S|Rognum, Torleiv O|Skotheim, Rolf I|Thiis-Evensen, Espen|Lothe, Ragnhild A
PMID: 19117505
Journal: Mol Biol (Mosk). 2008 Nov-Dec;42(6):1040-7.
Title: [Molecular-genetic analysis of clonal intratumoral heterogeneity on colorectal adenocarcinomas].
Author: Nemtsova, M N|Pal'tseva, E M|Babaian, A Iu|Mikhailenko, D S|Babenko, O V|Samofalova, O Iu|Tsar'kov, P V|Zaletaev, D V
PMID: 19140325
Journal: Mol Med Rep. 2008 Jan-Feb;1(1):27-32.
Title: p16, cyclin D1 and Rb expression in colorectal carcinomas: Correlations with clinico-pathological parameters and prognosis.
Author: Von Stockmar-Von Wangenheim, Caroline A S|Monig, Stefan P|Schneider, Paul M|Landsberg, Stephanie|Drebber, Uta|Holscher, Arnulf H|Dienes, Hans P|Baldus, Stephan E
PMID: 21479373
Journal: Genes Chromosomes Cancer. 2009 Jan;48(1):1-9.
Title: Oncogenetic tree model of somatic mutations and DNA methylation in colon tumors.
Author: Sweeney, Carol|Boucher, Kenneth M|Samowitz, Wade S|Wolff, Roger K|Albertsen, Hans|Curtin, Karen|Caan, Bette J|Slattery, Martha L
PMID: 18767147
Journal: Gut. 2009 Jan;58(1):90-6.
Title: CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer.
Author: Ogino, Shuji|Nosho, Katsuhiko|Kirkner, Gregory J|Kawasaki, Takako|Meyerhardt, Jeffrey A|Loda, Massimo|Giovannucci, Edward L|Fuchs, Charles S
PMID: 18832519
Journal: Gastroenterology. 2009 Jan;136(1):196-205.e2.
Title: p16INK4a is a beta-catenin target gene and indicates low survival in human colorectal tumors.
Author: Wassermann, Stella|Scheel, Silvio K|Hiendlmeyer, Elke|Palmqvist, Richard|Horst, David|Hlubek, Falk|Haynl, Angela|Kriegl, Lydia|Reu, Simone|Merkel, Susanne|Brabletz, Thomas|Kirchner, Thomas|Jung, Andreas
PMID: 18951899
Journal: Chemotherapy. 2009;55(1):6-10.
Title: Quercetin is able to demethylate the p16INK4a gene promoter.
Author: Tan, Sainan|Wang, Chong|Lu, Cailing|Zhao, Baojian|Cui, Yi|Shi, Xinquan|Ma, Xu
PMID: 18974642
Journal: J Clin Pathol. 2009 Sep;62(9):777-85.
Title: Molecular pathology of endometrial carcinoma: practical aspects from the diagnostic and therapeutic viewpoints.
Author: Llobet, D|Pallares, J|Yeramian, A|Santacana, M|Eritja, N|Velasco, A|Dolcet, X|Matias-Guiu, X
PMID: 18977806
Journal: Am J Surg Pathol. 2009 Apr;33(4):572-82.
Title: Clinical, pathologic, and molecular features of early-onset colorectal carcinoma.
Author: Yantiss, Rhonda K|Goodarzi, Mahmoud|Zhou, Xi K|Rennert, Hanna|Pirog, Edyta C|Banner, Barbara F|Chen, Yao-Tseng
PMID: 19047896
Journal: J Gastrointest Surg. 2009 Jun;13(6):1151-4.
Title: Novel presentation of a familial pancreatic cancer syndrome.
Author: Maker, Ajay V|Warth, James A|Zinner, Michael J
PMID: 19089513
Journal: Neoplasia. 2009 Jan;11(1):87-95.
Title: JC virus T-antigen in colorectal cancer is associated with p53 expression and chromosomal instability, independent of CpG island methylator phenotype.
Author: Nosho, Katsuhiko|Shima, Kaori|Kure, Shoko|Irahara, Natsumi|Baba, Yoshifumi|Chen, Li|Kirkner, Gregory J|Fuchs, Charles S|Ogino, Shuji
PMID: 19107235
Journal: Clin Cancer Res. 2009 Feb 15;15(4):1155-61.
Title: Distinct BRAF (V600E) and KRAS mutations in high microsatellite instability sporadic colorectal cancer in African Americans.
Author: Kumar, Krishan|Brim, Hassan|Giardiello, Francis|Smoot, Duane T|Nouraie, Mehdi|Lee, Edward L|Ashktorab, Hassan
PMID: 19190129
Journal: Hum Pathol. 2009 May;40(5):639-44.
Title: Prognostic value of aspartyl (asparaginyl)-beta-hydroxylase/humbug expression in non-small cell lung carcinoma.
Author: Luu, Martin|Sabo, Edmond|de la Monte, Suzanne M|Greaves, Wesley|Wang, JiYi|Tavares, Rosemarie|Simao, Lelia|Wands, Jack R|Resnick, Murray B|Wang, LiJuan
PMID: 19200576
Journal: Hum Mutat. 2009 Apr;30(4):661-8.
Title: Genotype and haplotype analysis of cell cycle genes in sporadic colorectal cancer in the Czech Republic.
Author: Polakova, V|Pardini, B|Naccarati, A|Landi, S|Slyskova, J|Novotny, J|Vodickova, L|Bermejo, J L|Hanova, M|Smerhovsky, Z|Tulupova, E|Kumar, R|Hemminki, K|Vodicka, P
PMID: 19224585
Journal: Lab Invest. 2009 Jun;89(6):717-25.
Title: Inhibition of STAT5 induces G1 cell cycle arrest and reduces tumor cell invasion in human colorectal cancer cells.
Author: Xiong, Hua|Su, Wen-Yu|Liang, Qin-Chuan|Zhang, Zhi-Gang|Chen, Hui-Min|Du, Wan|Chen, Ying-Xuan|Fang, Jing-Yuan
PMID: 19290007
Journal: Anticancer Res. 2009 Jan;29(1):275-7.
Title: Aberrant methylation of the p16 gene is frequently detected in advanced colorectal cancer.
Author: Goto, Tetsuhiro|Mizukami, Hiroki|Shirahata, Atsushi|Sakata, Makiko|Saito, Mitsuo|Ishibashi, Kazuyoshi|Kigawa, Gaku|Nemoto, Hiroshi|Sanada, Yutaka|Hibi, Kenji
PMID: 19331161
Journal: Int J Cancer. 2009 Jul 1;125(1):158-64.
Title: Somatic alterations, metabolizing genes and smoking in rectal cancer.
Author: Curtin, Karen|Samowitz, Wade S|Wolff, Roger K|Herrick, Jennifer|Caan, Bette J|Slattery, Martha L
PMID: 19358278
Journal: Mol Cancer Ther. 2009 Apr;8(4):779-85.
Title: Growth inhibition of human cancer cells by 5-aza-2'-deoxycytidine does not correlate with its effects on INK4a/ARF expression or initial promoter methylation status.
Author: Xiong, Jingbo|Epstein, Richard J
PMID: 19372550
Journal: Clin Cancer Res. 2009 May 1;15(9):3156-62.
Title: Utility of p16 immunohistochemistry for the identification of Lynch syndrome.
Author: Paya, Artemio|Alenda, Cristina|Perez-Carbonell, Lucia|Rojas, Estefania|Soto, Jose-Luis|Guillen, Carmen|Castillejo, Adela|Barbera, Victor M|Carrato, Alfredo|Castells, Antoni|Llor, Xavier|Andreu, Montserrat|Koh, Jim|Enders, Greg H|Benlloch, Susana|Jover, Ro
PMID: 19383812
Journal: J Surg Oncol. 2009 Jul 1;100(1):69-74.
Title: Promoter hypermethylation of tumor-related genes in peritoneal lavage and the prognosis of patients with colorectal cancer.
Author: Kamiyama, Hidenori|Noda, Hiroshi|Takata, Osamu|Suzuki, Koichi|Kawamura, Yutaka|Konishi, Fumio
PMID: 19384904
Journal: Am J Gastroenterol. 2009 May;104(5):1093-6.
Title: Biomarkers in gastroenterology: between hope and hype comes histopathology.
Author: Jankowski, Janusz A|Odze, Robert D
PMID: 19417749
Journal: Mod Pathol. 2009 Jul;22(7):922-32.
Title: SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Author: Nosho, Katsuhiko|Shima, Kaori|Irahara, Natsumi|Kure, Shoko|Firestein, Ron|Baba, Yoshifumi|Toyoda, Saori|Chen, Li|Hazra, Aditi|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji
PMID: 19430421
Journal: Clin Cancer Res. 2009 Jun 1;15(11):3663-71.
Title: DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer.
Author: Nosho, Katsuhiko|Shima, Kaori|Irahara, Natsumi|Kure, Shoko|Baba, Yoshifumi|Kirkner, Gregory J|Chen, Li|Gokhale, Sumita|Hazra, Aditi|Spiegelman, Donna|Giovannucci, Edward L|Jaenisch, Rudolf|Fuchs, Charles S|Ogino, Shuji
PMID: 19470733
Journal: Mol Cancer Ther. 2009 Jul;8(7):1964-73.
Title: Epigenetic mechanisms of irinotecan sensitivity in colorectal cancer cell lines.
Author: Crea, Francesco|Giovannetti, Elisa|Cortesi, Filippo|Mey, Valentina|Nannizzi, Sara|Gallegos Ruiz, Marielle I|Ricciardi, Simona|Del Tacca, Mario|Peters, Godefridus J|Danesi, Romano
PMID: 19531575
Journal: Dis Colon Rectum. 2009 Jul;52(7):1304-11.
Title: A comparison of colon and rectal somatic DNA alterations.
Author: Slattery, Martha L|Curtin, Karen|Wolff, Roger K|Boucher, Kenneth M|Sweeney, Carol|Edwards, Sandra|Caan, Bette J|Samowitz, Wade
PMID: 19571709
Journal: Mol Carcinog. 2009 Nov;48(11):989-94.
Title: MSH6 G39E polymorphism and CpG island methylator phenotype in colon cancer.
Author: Curtin, Karen|Samowitz, Wade S|Wolff, Roger K|Caan, Bette J|Ulrich, Cornelia M|Potter, John D|Slattery, Martha L
PMID: 19582761
Journal: Cancer Causes Control. 2009 Nov;20(9):1763-8.
Title: Microsatellite instability and survival in rectal cancer.
Author: Samowitz, Wade S|Curtin, Karen|Wolff, Roger K|Tripp, Sheryl R|Caan, Bette J|Slattery, Martha L
PMID: 19669908
Journal: Gastroenterology. 2009 Nov;137(5):1609-20.e1-3.
Title: A prospective cohort study shows unique epigenetic, genetic, and prognostic features of synchronous colorectal cancers.
Author: Nosho, Katsuhiko|Kure, Shoko|Irahara, Natsumi|Shima, Kaori|Baba, Yoshifumi|Spiegelman, Donna|Meyerhardt, Jeffrey A|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji
PMID: 19686742
Journal: Cancer Causes Control. 2009 Nov;20(9):1769-77.
Title: Genetic variants in the cell cycle control pathways contribute to early onset colorectal cancer in Lynch syndrome.
Author: Chen, Jinyun|Etzel, Carol J|Amos, Christopher I|Zhang, Qing|Viscofsky, Nancy|Lindor, Noralane M|Lynch, Patrick M|Frazier, Marsha L
PMID: 19690970
Journal: Cancer Prev Res (Phila). 2009 Sep;2(9):800-6.
Title: Chemoprevention of mouse intestinal tumorigenesis by the cyclin-dependent kinase inhibitor SNS-032.
Author: Boquoi, Amelie|Chen, Tina|Enders, Greg H
PMID: 19723896
Journal: Mod Pathol. 2009 Dec;22(12):1588-99.
Title: MGMT methylation is associated primarily with the germline C>T SNP (rs16906252) in colorectal cancer and normal colonic mucosa.
Author: Hawkins, Nicholas J|Lee, James H-F|Wong, Justin J-L|Kwok, Chau-To|Ward, Robyn L|Hitchins, Megan P
PMID: 19734844
Journal: Cancer Prev Res (Phila). 2009 Sep;2(9):814-22.
Title: Concordant DNA methylation in synchronous colorectal carcinomas.
Author: Konishi, Kazuo|Shen, Lanlan|Jelinek, Jaroslav|Watanabe, Yoshiyuki|Ahmed, Saira|Kaneko, Kazuhiro|Kogo, Mari|Takano, Toshihumi|Imawari, Michio|Hamilton, Stanley R|Issa, Jean-Pierre J
PMID: 19737982
Journal: Bull Cancer. 2009 Oct;96(10):941-50.
Title: [Involvement of human papillomavirus in upper aero-digestive tracts cancers].
Author: Neufcoeur, P Ernoux|Arafa, M|Delvenne, P|Saussez, S
PMID: 19744917
Journal: J Int Med Res. 2009 Jul-Aug;37(4):1038-45.
Title: Methylation in p14(ARF) is frequently observed in colorectal cancer with low-level microsatellite instability.
Author: Kominami, K|Nagasaka, T|Cullings, H M|Hoshizima, N|Sasamoto, H|Young, J|Leggett, B A|Tanaka, N|Matsubara, N
PMID: 19761686
Journal: Clin Cancer Res. 2009 Oct 1;15(19):6185-91.
Title: Aberrant methylation of APC, MGMT, RASSF2A, and Wif-1 genes in plasma as a biomarker for early detection of colorectal cancer.
Author: Lee, Bo Bin|Lee, Eun Ju|Jung, Eun Hyun|Chun, Ho-Kyung|Chang, Dong Kyoung|Song, Sang Yong|Park, Joobae|Kim, Duk-Hwan
PMID: 19773381
Journal: Cancer Epidemiol Biomarkers Prev. 2009 Oct;18(10):2765-72.
Title: Vitamin D receptor expression is associated with PIK3CA and KRAS mutations in colorectal cancer.
Author: Kure, Shoko|Nosho, Katsuhiko|Baba, Yoshifumi|Irahara, Natsumi|Shima, Kaori|Ng, Kimmie|Meyerhardt, Jeffrey A|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji
PMID: 19789368
Journal: Clin Cancer Res. 2009 Oct 15;15(20):6412-20.
Title: Lymphocytic reaction to colorectal cancer is associated with longer survival, independent of lymph node count, microsatellite instability, and CpG island methylator phenotype.
Author: Ogino, Shuji|Nosho, Katsuhiko|Irahara, Natsumi|Meyerhardt, Jeffrey A|Baba, Yoshifumi|Shima, Kaori|Glickman, Jonathan N|Ferrone, Cristina R|Mino-Kenudson, Mari|Tanaka, Noriko|Dranoff, Glenn|Giovannucci, Edward L|Fuchs, Charles S
PMID: 19825961
Journal: J Cell Mol Med. 2009 Sep;13(9B):3668-79.
Title: Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signalling.
Author: Xiong, Hua|Chen, Zhao-Fei|Liang, Qin-Chuan|Du, Wan|Chen, Hui-Min|Su, Wen-Yu|Chen, Guo-Qiang|Han, Ze-Guang|Fang, Jing-Yuan
PMID: 20196786
Journal: Gastroenterology Res. 2009 Dec;2(6):311-316.
Title: No Association of Obesity and Type 2 Diabetes Mellitus Related Genetic Variants With Colon Cancer.
Author: Thompson, Cheryl L|Plummer, Sarah J|Tucker, Thomas C|Casey, Graham|Li, Li
PMID: 27990199
Journal: Colorectal Dis. 2010 Apr;12(4):316-23.
Title: Expression of cyclin D2 is an independent predictor of the development of hepatic metastasis in colorectal cancer.
Author: Sarkar, R|Hunter, I A|Rajaganeshan, R|Perry, S L|Guillou, P|Jayne, D G
PMID: 19508551
Journal: Neuropathology. 2010 Jun;30(3):273-8.
Title: Intramedullary solitary fibrous tumor of dorsal spinal cord.
Author: Ciappetta, Pasqualino|D'Urso, Pietro Ivo|Cimmino, Antonia|Ingravallo, Giuseppe|Rossi, Roberta|Colamaria, Antonio|D'Urso, Oscar Fernando
PMID: 19751244
Journal: Mol Carcinog. 2010 Jan;49(1):94-103.
Title: Aberrant DNA methylation occurs in colon neoplasms arising in the azoxymethane colon cancer model.
Author: Borinstein, Scott C|Conerly, Melissa|Dzieciatkowski, Slavomir|Biswas, Swati|Washington, M Kay|Trobridge, Patty|Henikoff, Steve|Grady, William M
PMID: 19777566
Journal: J Cancer Res Clin Oncol. 2010 Feb;136(2):323-31.
Title: Aberrant p16((INK4a)) methylation is a frequent event in colorectal cancers: prognostic value and relation to mRNA expression and immunoreactivity.
Author: Mitomi, Hiroyuki|Fukui, Naoshi|Tanaka, Nobuho|Kanazawa, Hideki|Saito, Tsuyoshi|Matsuoka, Takashi|Yao, Takashi
PMID: 19779933
Journal: Oncol Rep. 2010 Jan;23(1):191-7.
Title: CpG island methylation of BNIP3 predicts resistance against S-1/CPT-11 combined therapy in colorectal cancer patients.
Author: Hiraki, Masatsugu|Kitajima, Yoshihiko|Nakafusa, Yuji|Nakamura, Jun|Hashiguchi, Kazuyoshi|Sumi, Kenji|Noshiro, Hirokazu|Miyazaki, Kohji
PMID: 19956881
Journal: Ann Surg Oncol. 2010 Jul;17(7):1767-76.
Title: Promoter methylation of specific genes is associated with the phenotype and progression of colorectal adenocarcinomas.
Author: Kim, Jin C|Choi, Jin S|Roh, Seon A|Cho, Dong H|Kim, Tae W|Kim, Yong S
PMID: 20077021
Journal: PLoS One. 2010 Jan 19;5(1):e8777.
Title: Aberrant gene promoter methylation associated with sporadic multiple colorectal cancer.
Author: Gonzalo, Victoria|Lozano, Juan Jose|Munoz, Jenifer|Balaguer, Francesc|Pellise, Maria|Rodriguez de Miguel, Cristina|Andreu, Montserrat|Jover, Rodrigo|Llor, Xavier|Giraldez, M Dolores|Ocana, Teresa|Serradesanferm, Anna|Alonso-Espinaco, Virginia|Jimeno, Mire
PMID: 20098741
Journal: Cancer Epidemiol. 2010 Apr;34(2):194-9.
Title: Immunoprecipitation of nucleosomal DNA is a novel procedure to improve the sensitivity of serum screening for the p16 hypermethylation associated with colon cancer.
Author: Sakamoto, Jun|Fujiya, Mikihiro|Okamoto, Kotaro|Nata, Toshie|Inaba, Yuhei|Moriichi, Kentaro|Tanabe, Hiroki|Mizukami, Yusuke|Watari, Jiro|Ashida, Toshifumi|Kohgo, Yutaka
PMID: 20129840
Journal: Am J Gastroenterol. 2010 Jul;105(7):1610-9.
Title: Methylation status of genes in non-neoplastic mucosa from patients with ulcerative colitis-associated colorectal cancer.
Author: Garrity-Park, Megan M|Loftus, Edward V Jr|Sandborn, William J|Bryant, Sandra C|Smyrk, Thomas C
PMID: 20160714
Journal: Carcinogenesis. 2010 May;31(5):812-9.
Title: Secreted protein acidic and rich in cysteine-induced cellular senescence in colorectal cancers in response to irinotecan is mediated by P53.
Author: Chan, Justin M|Ho, Shirley H|Tai, Isabella T
PMID: 20164124
Journal: Cancer Epidemiol Biomarkers Prev. 2010 Mar;19(3):822-31.
Title: PTGER2 overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype.
Author: Baba, Yoshifumi|Nosho, Katsuhiko|Shima, Kaori|Goessling, Wolfram|Chan, Andrew T|Ng, Kimmie|Chan, Jennifer A|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji
PMID: 20200425
Journal: Arch Neurol. 2010 Mar;67(3):275-8.
Title: New insights into susceptibility to glioma.
Author: Liu, Yanhong|Shete, Sanjay|Hosking, Fay J|Robertson, Lindsay B|Bondy, Melissa L|Houlston, Richard S
PMID: 20212223
Journal: Int J Radiat Oncol Biol Phys. 2010 Apr;76(5):1512-9.
Title: Impact of genomic methylation on radiation sensitivity of colorectal carcinoma.
Author: Hofstetter, Barbara|Niemierko, Andrzej|Forrer, Christian|Benhattar, Jean|Albertini, Veronica|Pruschy, Martn|Bosman, Fred T|Catapano, Carlo V|Ciernik, I Frank
PMID: 20338477
Journal: BMC Cancer. 2010 Mar 26;10:117.
Title: Detection of HPV and the role of p16INK4A overexpression as a surrogate marker for the presence of functional HPV oncoprotein E7 in colorectal cancer.
Author: Deschoolmeester, Vanessa|Van Marck, Veerle|Baay, Marc|Weyn, Christine|Vermeulen, Peter|Van Marck, Eric|Lardon, Filip|Fontaine, Veronique|Vermorken, Jan B
PMID: 20346145
Journal: J Mol Med (Berl). 2010 Jun;88(6):609-22.
Title: Systematic genetic dissection of p14ARF-mediated mitochondrial cell death signaling reveals a key role for p21CDKN1 and the BH3-only protein Puma/bbc3.
Author: Hemmati, Philipp G|Muer, Annika|Gillissen, Bernd|Overkamp, Tim|Milojkovic, Ana|Wendt, Jana|Dorken, Bernd|Daniel, Peter T
PMID: 20419447
Journal: FASEB J. 2010 Sep;24(9):3360-9.
Title: Intake of grape-derived polyphenols reduces C26 tumor growth by inhibiting angiogenesis and inducing apoptosis.
Author: Walter, Allison|Etienne-Selloum, Nelly|Brasse, David|Khallouf, Hadeel|Bronner, Christian|Rio, Marie-Christine|Beretz, Alain|Schini-Kerth, Valerie B
PMID: 20442318
Journal: PLoS One. 2010 Apr 29;5(4):e10338.
Title: HOXB13, a target of DNMT3B, is methylated at an upstream CpG island, and functions as a tumor suppressor in primary colorectal tumors.
Author: Ghoshal, Kalpana|Motiwala, Tasneem|Claus, Rainer|Yan, Pearlly|Kutay, Huban|Datta, Jharna|Majumder, Sarmila|Bai, Shoumei|Majumder, Arnab|Huang, Tim|Plass, Christoph|Jacob, Samson T
PMID: 20454457
Journal: Cancer Res. 2010 Jun 1;70(11):4749-58.
Title: ARF suppresses tumor angiogenesis through translational control of VEGFA mRNA.
Author: Kawagishi, Hiroyuki|Nakamura, Hideaki|Maruyama, Mitsuo|Mizutani, Shuki|Sugimoto, Kazushi|Takagi, Masatoshi|Sugimoto, Masataka
PMID: 20501856
Journal: Epigenetics. 2010 Aug 16;5(6):547-56. Epub 2010 Aug 16.
Title: Ischemia dysregulates DNA methyltransferases and p16INK4a methylation in human colorectal cancer cells.
Author: Skowronski, Karolina|Dubey, Sonam|Rodenhiser, David|Coomber, Brenda
PMID: 20543577
Journal: Minerva Chir. 2010 Apr;65(2):235-42.
Title: [Stem cells and colorectal cancerogenesis: new insight].
Author: Pasqua Ferrara, A|Scalera, I|Rotelli, M T|Rinaldi, M|Altomare, D F
PMID: 20548278
Journal: Mol Med. 2010 Sep-Oct;16(9-10):425-32.
Title: MTHFR, MTR, and MTRR polymorphisms in relation to p16INK4A hypermethylation in mucosa of patients with colorectal cancer.
Author: Wettergren, Yvonne|Odin, Elisabeth|Carlsson, Goran|Gustavsson, Bengt
PMID: 20549016
Journal: Cancer. 2010 Oct 1;116(19):4474-86.
Title: Expression of p16 in lymph node metastases of adjuvantly treated stage III colorectal cancer patients identifies poor prognostic subgroups: a retrospective analysis of biomarkers in matched primary tumor and lymph node metastases.
Author: Karamitopoulou, Eva|Zlobec, Inti|Koumarianou, Anna|Patsouris, Efstratios S|Peros, George|Lugli, Alessandro
PMID: 20572035
Journal: Cell Cycle. 2010 Jun 15;9(12):2456-63. Epub 2010 Jun 15.
Title: Increased angiogenesis in Cdk4(R24C/R24C):Apc(+/Min) intestinal tumors.
Author: Abedin, Zahidur R|Ma, Zhongjie|Reddy, E Premkumar
PMID: 20603602
Journal: Clin Colorectal Cancer. 2010 Jul;9(3):168-76.
Title: Novel methylation panel for the early detection of colorectal tumors in stool DNA.
Author: Azuara, Daniel|Rodriguez-Moranta, Francisco|de Oca, Javier|Soriano-Izquierdo, Antonio|Mora, Josefina|Guardiola, Jordi|Biondo, Sebastiano|Blanco, Ignacio|Peinado, Miguel Angel|Moreno, Victor|Esteller, Manel|Capella, Gabriel
PMID: 20643622
Journal: World J Gastroenterol. 2010 Jul 28;16(28):3553-60.
Title: Promoter methylation status of hMLH1, MGMT, and CDKN2A/p16 in colorectal adenomas.
Author: Psofaki, Vasiliki|Kalogera, Chryssoula|Tzambouras, Nikolaos|Stephanou, Dimitrios|Tsianos, Epameinondas|Seferiadis, Konstantin|Kolios, Georgios
PMID: 20653064
Journal: Cancer Genet Cytogenet. 2010 Sep;201(2):128-32.
Title: Gene methylation of SFRP2, P16, DAPK1, HIC1, and MGMT and KRAS mutations in sporadic colorectal cancer.
Author: Pehlivan, Sacide|Artac, Mehmet|Sever, Tugce|Bozcuk, Hakan|Kilincarslan, Can|Pehlivan, Mustafa
PMID: 20682398
Journal: Cancer Cell. 2010 Aug 9;18(2):135-46.
Title: Ink4a/Arf and oncogene-induced senescence prevent tumor progression during alternative colorectal tumorigenesis.
Author: Bennecke, Moritz|Kriegl, Lydia|Bajbouj, Monther|Retzlaff, Kristin|Robine, Sylvie|Jung, Andreas|Arkan, Melek C|Kirchner, Thomas|Greten, Florian R
PMID: 20708155
Journal: Histopathology. 2010 Aug;57(2):233-43.
Title: Systematic assessment of protein phenotypes characterizing high-grade tumour budding in mismatch repair-proficient colorectal cancer.
Author: Karamitopoulou, Eva|Lugli, Alessandro|Panayiotides, Ioannis|Karakitsos, Petros|Peros, George|Rallis, George|Patsouris, Efstratios S|Terracciano, Luigi|Zlobec, Inti
PMID: 20716165
Journal: Oncogene. 2010 Dec 9;29(49):6464-74.
Title: Epigenetic inactivation of T-box transcription factor 5, a novel tumor suppressor gene, is associated with colon cancer.
Author: Yu, J|Ma, X|Cheung, K F|Li, X|Tian, L|Wang, S|Wu, C W|Wu, W K K|He, M|Wang, M|Ng, S S M|Sung, J J Y
PMID: 20802524
Journal: EMBO Mol Med. 2010 Nov;2(11):472-86.
Title: p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium.
Author: Cole, Alicia M|Ridgway, Rachel A|Derkits, Sahra E|Parry, Lee|Barker, Nick|Clevers, Hans|Clarke, Alan R|Sansom, Owen J
PMID: 20976827
Journal: Hepatogastroenterology. 2010 Jul-Aug;57(101):720-7.
Title: Detection of colorectal neoplasm using promoter methylation of ITGA4, SFRP2, and p16 in stool samples: a preliminary report in Korean patients.
Author: Chang, Eugene|Park, Dong Il|Kim, Young Jin|Kim, Bo Kyoung|Park, Jung Ho|Kim, Hong Joo|Cho, Yong Kyun|Sohn, Chong Il|Jeon, Woo Kyu|Kim, Byung Ik|Kim, Hung Dai|Kim, Dong Hoon|Kim, Young Ho
PMID: 21033217
Journal: Am J Pathol. 2010 Dec;177(6):2731-40.
Title: Novel application of structural equation modeling to correlation structure analysis of CpG island methylation in colorectal cancer.
Author: Tanaka, Noriko|Huttenhower, Curtis|Nosho, Katsuhiko|Baba, Yoshifumi|Shima, Kaori|Quackenbush, John|Haigis, Kevin M|Giovannucci, Edward|Fuchs, Charles S|Ogino, Shuji
PMID: 21037082
Journal: J Gastroenterol Hepatol. 2010 Nov;25(11):1800-5.
Title: Increased expression of ubiquitin-specific protease 22 can promote cancer progression and predict therapy failure in human colorectal cancer.
Author: Liu, Yan Long|Yang, Yan Mei|Xu, Hui|Dong, Xin Shu
PMID: 21039844
Journal: Zhong Xi Yi Jie He Xue Bao. 2010 Nov;8(11):1048-52.
Title: [Senescence-inducing effects of Chinese herbal medicine Tenglong Buzhong Decoction on human colon carcinoma LS-174-T cells and the mechanism].
Author: Hu, Bing|An, Hong-mei|Shen, Ke-ping|Du, Qin
PMID: 21078269
Journal: Ann Nutr Metab. 2010;57(3-4):183-9.
Title: Epigenetic control of estrogen receptor expression and tumor suppressor genes is modulated by bioactive food compounds.
Author: Berner, Carolin|Aumuller, Eva|Gnauck, Anne|Nestelberger, Manuela|Just, A|Haslberger, Alexander G
PMID: 21088384
Journal: Int J Biol Sci. 2010 Dec 6;6(7):784-95.
Title: S-adenosylmethionine inhibits the growth of cancer cells by reversing the hypomethylation status of c-myc and H-ras in human gastric cancer and colon cancer.
Author: Luo, Jin|Li, Yan-Ni|Wang, Fei|Zhang, Wei-Ming|Geng, Xin
PMID: 21152119
Journal: World J Gastrointest Oncol. 2010 Jul 15;2(7):295-303.
Title: Aberrant promoter methylation of p16 in colorectal adenocarcinoma in North Indian patients.
Author: Malhotra, Pooja|Kochhar, Rakesh|Vaiphei, Kim|Wig, Jai Dev|Mahmood, Safrun
PMID: 21160660
Journal: Anticancer Res. 2010 Dec;30(12):4811-8.
Title: Aberrant methylation of heparan sulfate glucosamine 3-O-sulfotransferase 2 genes as a biomarker in colorectal cancer.
Author: Tokuyama, Yasuharu|Takahashi, Takao|Okumura, Naoki|Nonaka, Kenichi|Kawaguchi, Yoshihiro|Yamaguchi, Kazuya|Osada, Shinji|Gazdar, Adi|Yoshida, Kazuhiro
PMID: 21187457
Journal: Klin Onkol. 2010;23(6):388-400.
Title: Genetic testing and prevention of hereditary cancer at the MMCI--over 10 years of experience.
Author: Foretova, L|Petrakova, K|Palacova, M|Kalabova, R|Svoboda, M|Navratilova, M|Schneiderova, M|Bolcak, K|Krejci, E|Drazan, L|Mikova, M|Hazova, J|Vasickova, P|Machackova, E
PMID: 21348412
Journal: Int J Cancer. 2011 Mar 1;128(5):1080-94.
Title: Prognostic significance of CDKN2A (p16) promoter methylation and loss of expression in 902 colorectal cancers: Cohort study and literature review.
Author: Shima, Kaori|Nosho, Katsuhiko|Baba, Yoshifumi|Cantor, Mami|Meyerhardt, Jeffrey A|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji
PMID: 20473920
Journal: Int J Colorectal Dis. 2011 Feb;26(2):127-33.
Title: Signet-ring cell carcinoma of colorectum--current perspectives and molecular biology.
Author: Gopalan, Vinod|Smith, Robert Anthony|Ho, Yik-Hong|Lam, Alfred King-Yin
PMID: 20686774
Journal: Biosci Rep. 2011 Aug;31(4):257-64.
Title: Aberrant methylation of hMLH1 and p16INK4a in Tunisian patients with sporadic colorectal adenocarcinoma.
Author: Miladi-Abdennadher, Imen|Abdelmaksoud-Damak, Rania|Ayadi, Lobna|Khabir, Abdelmajid|Frikha, Foued|Kallel, Lamia|Frikha, Mounir|Sellami-Boudawara, Tahia|Gargouri, Ali|Mokdad-Gargouri, Raja
PMID: 20815811
Journal: Gut. 2011 Apr;60(4):499-508.
Title: Sequential DNA methylation changes are associated with DNMT3B overexpression in colorectal neoplastic progression.
Author: Ibrahim, Ashraf E K|Arends, Mark J|Silva, Ana-Luisa|Wyllie, Andrew H|Greger, Liliana|Ito, Yoko|Vowler, Sarah L|Huang, Tim H-M|Tavare, Simon|Murrell, Adele|Brenton, James D
PMID: 21068132
Journal: Oncol Rep. 2011 Jan;25(1):167-72.
Title: Polymorphisms in genes involved in folate metabolism and plasma DNA methylation in colorectal cancer patients.
Author: Kim, Jong Woo|Park, Hye Mi|Choi, Young-Kook|Chong, So Young|Oh, Doyeun|Kim, Nam Keun
PMID: 21109973
Journal: Oncol Rep. 2011 Jan;25(1):253-8.
Title: Tissue sampling for mutation analysis in colorectal cancer: K-ras is homogeneously distributed throughout the tumor tissue.
Author: Ekelund, Susanne|Papadogiannakis, Nikos|Olivecrona, Hans|Lindforss, Ulrik
PMID: 21109984
Journal: Cancer Causes Control. 2011 Feb;22(2):301-9.
Title: MGMT promoter methylation, loss of expression and prognosis in 855 colorectal cancers.
Author: Shima, Kaori|Morikawa, Teppei|Baba, Yoshifumi|Nosho, Katsuhiko|Suzuki, Maiko|Yamauchi, Mai|Hayashi, Marika|Giovannucci, Edward|Fuchs, Charles S|Ogino, Shuji
PMID: 21140203
Journal: Oncol Rep. 2011 Mar;25(3):789-94.
Title: Effect of classification based on combination of mutation and methylation in colorectal cancer prognosis.
Author: Aoyagi, Haruhiko|Iida, Satoru|Uetake, Hiroyuki|Ishikawa, Toshiaki|Takagi, Yoko|Kobayashi, Hirotoshi|Higuchi, Tetsuro|Yasuno, Masamichi|Enomoto, Masayuki|Sugihara, Kenichi
PMID: 21174064
Journal: Fam Cancer. 2011 Jun;10(2):323-30.
Title: German national case collection for familial pancreatic cancer (FaPaCa): ten years experience.
Author: Schneider, Ralph|Slater, Emily P|Sina, Mercede|Habbe, Nils|Fendrich, Volker|Matthai, Elvira|Langer, Peter|Bartsch, Detlef K
PMID: 21207249
Journal: Diagn Pathol. 2011 Jan 11;6:5.
Title: Primary acantholytic squamous cell carcinoma of the cecum: a case report.
Author: Jukic, Zoran|Ledinsky, Iva|Ulamec, Monika|Ledinsky, Mario|Kruslin, Bozo|Tomas, Davor
PMID: 21223553
Journal: Pathology. 2011 Feb;43(2):133-7.
Title: Loss of E-cadherin independently predicts the lymph node status in colorectal cancer.
Author: Karamitopoulou, E|Zlobec, I|Patsouris, Es|Peros, G|Lugli, A
PMID: 21233674
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2011 Jan;14(1):52-6.
Title: [Gene methylation in stool for the screening of colorectal cancer and pre-malignant lesions].
Author: Kang, Yan-Ping|Cao, Fu-Ao|Chang, Wen-Jun|Lou, Zheng|Wang, Hao|Wu, Ling-Ling|Fu, Chuan-Gang|Cao, Guang-Wen
PMID: 21271382
Journal: Cancer Chemother Pharmacol. 2011 Oct;68(4):871-8.
Title: Cetuximab enhances the activities of irinotecan on gastric cancer cell lines through downregulating the EGFR pathway upregulated by irinotecan.
Author: Liu, Xin|Guo, Wei-Jian|Zhang, Xiao-Wei|Cai, Xu|Tian, Shu|Li, Jin
PMID: 21286718
Journal: Cancer Res. 2011 Mar 1;71(5):1669-79.
Title: Ulcerative colitis-associated colorectal cancer arises in a field of short telomeres, senescence, and inflammation.
Author: Risques, Rosa Ana|Lai, Lisa A|Himmetoglu, Cigdem|Ebaee, Anoosheh|Li, Lin|Feng, Ziding|Bronner, Mary P|Al-Lahham, Bassel|Kowdley, Kris V|Lindor, Keith D|Rabinovitch, Peter S|Brentnall, Teresa A
PMID: 21363920
Journal: Radiat Res. 2011 May;175(5):575-87.
Title: The effect of radiation quality on genomic DNA methylation profiles in irradiated human cell lines.
Author: Goetz, Wilfried|Morgan, Michelle N M|Baulch, Janet E
PMID: 21375360
Journal: Clin Cancer Res. 2011 May 1;17(9):2919-33.
Title: The histone methyltransferase and putative oncoprotein MMSET is overexpressed in a large variety of human tumors.
Author: Hudlebusch, Heidi Rye|Santoni-Rugiu, Eric|Simon, Ronald|Ralfkiaer, Elisabeth|Rossing, Henrik Holm|Johansen, Jens Vilstrup|Jorgensen, Mette|Sauter, Guido|Helin, Kristian
PMID: 21385930
Journal: Mod Pathol. 2011 Jul;24(7):1015-22.
Title: Up and downregulation of p16(Ink4a) expression in BRAF-mutated polyps/adenomas indicates a senescence barrier in the serrated route to colon cancer.
Author: Kriegl, Lydia|Neumann, Jens|Vieth, Michael|Greten, Florian R|Reu, Simone|Jung, Andreas|Kirchner, Thomas
PMID: 21423154
Journal: Pathol Oncol Res. 2011 Dec;17(4):819-25.
Title: High frequency of genes' promoter methylation, but lack of BRAF V600E mutation among Iranian colorectal cancer patients.
Author: Naghibalhossaini, Fakhraddin|Hosseini, Hamideh Mahmoodzadeh|Mokarram, Pooneh|Zamani, Mozhdeh
PMID: 21455633
Journal: Cancer. 2011 May 1;117(9):1847-54.
Title: DNA methylation predicts recurrence from resected stage III proximal colon cancer.
Author: Ahn, Joong Bae|Chung, Woon Bok|Maeda, Osamu|Shin, Sang Joon|Kim, Hyun Soo|Chung, Hyun Chul|Kim, Nam Kyu|Issa, Jean-Pierre J
PMID: 21509761
Journal: Anticancer Res. 2011 May;31(5):1643-6.
Title: p16INK4a methylation in serum as a follow-up marker for recurrence of colorectal cancer.
Author: Nakayama, Goro|Kodera, Yasuhiro|Ohashi, Norifumi|Koike, Masahiko|Fujiwara, Michitaka|Nakao, Akimasa
PMID: 21617221
Journal: Int J Cancer. 2011 Nov 1;129(9):2115-23.
Title: Inhibition of VEGF induces cellular senescence in colorectal cancer cells.
Author: Hasan, Mohammad R|Ho, Shirley H Y|Owen, David A|Tai, Isabella T
PMID: 21618508
Journal: Tumour Biol. 2011 Aug;32(4):653-9.
Title: Detection of viral DNA sequences in sporadic colorectal cancers in relation to CpG island methylation and methylator phenotype.
Author: Karpinski, Pawel|Myszka, Aleksander|Ramsey, David|Kielan, Wojciech|Sasiadek, Maria Malgorzata
PMID: 21625944
Journal: Hum Pathol. 2011 Dec;42(12):1888-96.
Title: Systematic analysis of proteins from different signaling pathways in the tumor center and the invasive front of colorectal cancer.
Author: Karamitopoulou, Eva|Zlobec, Inti|Panayiotides, Ioannis|Patsouris, Efstratios S|Peros, George|Rallis, George|Lapas, Christos|Karakitsos, Petros|Terracciano, Luigi M|Lugli, Alessandro
PMID: 21664646
Journal: Histopathology. 2011 Jul;59(1):98-105.
Title: Immunohistochemical investigation of tumorigenic pathways in sinonasal intestinal-type adenocarcinoma. A tissue microarray analysis of 62 cases.
Author: Franchi, Alessandro|Palomba, Annarita|Fondi, Cristina|Miligi, Lucia|Paglierani, Milena|Pepi, Monica|Santucci, Marco
PMID: 21668475
Journal: Cancer Lett. 2011 Oct 1;309(1):78-84.
Title: SUMO-specific protease 1 regulates the in vitro and in vivo growth of colon cancer cells with the upregulated expression of CDK inhibitors.
Author: Xu, Ying|Li, Jie|Zuo, Yong|Deng, Jiong|Wang, Li-Shun|Chen, Guo-Qiang
PMID: 21669491
Journal: Int J Oncol. 2011 Sep;39(3):683-8.
Title: Hypermethylation of promoter regions of the APC1A and p16INK4a genes in relation to prognosis and tumor characteristics in cervical cancer patients.
Author: Lof-Ohlin, Zarah M|Sorbe, Bengt|Wingren, Sten|Nilsson, Torbjorn K
PMID: 21674126
Journal: Gastroenterology. 2011 Sep;141(3):1003-1013.e1-10.
Title: Mutant KRAS promotes hyperplasia and alters differentiation in the colon epithelium but does not expand the presumptive stem cell pool.
Author: Feng, Ying|Bommer, Guido T|Zhao, Jenny|Green, Maranne|Sands, Evan|Zhai, Yali|Brown, Kelly|Burberry, Aaron|Cho, Kathleen R|Fearon, Eric R
PMID: 21699772
Journal: PLoS One. 2011;6(6):e21102.
Title: B vitamins, methionine and alcohol intake and risk of colon cancer in relation to BRAF mutation and CpG island methylator phenotype (CIMP).
Author: Schernhammer, Eva S|Giovannucci, Edward|Baba, Yoshifumi|Fuchs, Charles S|Ogino, Shuji
PMID: 21738611
Journal: Cancer Prev Res (Phila). 2011 Dec;4(12):1961-72.
Title: Mechanistic contribution of ubiquitous 15-lipoxygenase-1 expression loss in cancer cells to terminal cell differentiation evasion.
Author: Moussalli, Micheline J|Wu, Yuanqing|Zuo, Xiangsheng|Yang, Xiu L|Wistuba, Ignacio Ivan|Raso, Maria G|Morris, Jeffrey S|Bowser, Jessica L|Minna, John D|Lotan, Reuben|Shureiqi, Imad
PMID: 21881028
Journal: Appl Immunohistochem Mol Morphol. 2011 Dec;19(6):562-8.
Title: Expression of p16INK4a, alone or combined with p53, is predictive of better prognosis in colorectal adenocarcinoma in Tunisian patients.
Author: Miladi-Abdennadher, Imen|Abdelmaksoud-Damak, Rania|Ayadi, Lobna|Khabir, Abdelmajid|Amouri, Ali|Frikha, Foued|Ellouz, Sameh|Frikha, Mounir|Sellami-Boudawara, Tahia|Mokdad-Gargouri, Raja
PMID: 22095233
Journal: PLoS One. 2011;6(11):e27889.
Title: DNA methylation profiles of primary colorectal carcinoma and matched liver metastasis.
Author: Konishi, Kazuo|Watanabe, Yoshiyuki|Shen, Lanlan|Guo, Yi|Castoro, Ryan J|Kondo, Kimie|Chung, Woonbok|Ahmed, Saira|Jelinek, Jaroslav|Boumber, Yanis A|Estecio, Marcos R|Maegawa, Shinji|Kondo, Yutaka|Itoh, Fumio|Imawari, Michio|Hamilton, Stanley R|Issa, Jean-
PMID: 22132162
Journal: Zhonghua Yi Xue Za Zhi. 2011 Sep 6;91(33):2362-5.
Title: [Effects of 5-Aza-2'-deoxycytidine on the carcinogenesis of colorectal cancer in mouse and the in vivo expression of p16/CDKN(2) mRNA].
Author: Fang, Xiao-Ming|Jiang, Zhao-Hui|Yao, Ning|Ding, Xiao-Wen|Peng, Jia-Ping|Zheng, Shu
PMID: 22321754
Journal: Mol Carcinog. 2012 Feb;51(2):174-84.
Title: Trichostatin A, a histone deacetylase inhibitor, suppresses JAK2/STAT3 signaling via inducing the promoter-associated histone acetylation of SOCS1 and SOCS3 in human colorectal cancer cells.
Author: Xiong, Hua|Du, Wan|Zhang, Yan-Jie|Hong, Jie|Su, Wen-Yu|Tang, Jie-Ting|Wang, Ying-Chao|Lu, Rong|Fang, Jing-Yuan
PMID: 21520296
Journal: Cell Biochem Biophys. 2012 Jan;62(1):229-35.
Title: USP22 acts as an oncogene by the activation of BMI-1-mediated INK4a/ARF pathway and Akt pathway.
Author: Liu, Yan-Long|Jiang, Shi-Xiong|Yang, Yan-Mei|Xu, Hui|Liu, Jing-Lei|Wang, Xi-Shan
PMID: 21928107
Journal: Cell Signal. 2012 Mar;24(3):718-25.
Title: Stat6 activity-related Th2 cytokine profile and tumor growth advantage of human colorectal cancer cells in vitro and in vivo.
Author: Li, Ben Hui|Xu, Shuang Bing|Li, Feng|Zou, Xiao Guang|Saimaiti, Abudukeyoumu|Simayi, Dilixia|Wang, Ying Hong|Zhang, Yan|Yuan, Jia|Zhang, Wen Jie
PMID: 22108090
Journal: Dig Dis Sci. 2012 May;57(5):1261-70.
Title: Externalization of saw-tooth architecture in small serrated polyps implies the presence of methylation of IGFBP7.
Author: Kaji, Eisuke|Uraoka, Toshio|Kato, Jun|Hiraoka, Sakiko|Suzuki, Hideyuki|Akita, Mitsuhiro|Saito, Shunsuke|Tanaka, Takehiro|Ohara, Nobuya|Yamamoto, Kazuhide
PMID: 22173745
Journal: Mol Med Rep. 2012 Apr;5(4):1053-7.
Title: The blues of P(16)INK(4a): aberrant promoter methylation and association with colorectal cancer in the Kashmir valley.
Author: Sameer, A Syed|Abdullah, Safiya|Nissar, Saniya|Rasool, Roohi|Shah, Zaffar A|Afroze, Dil|Chowdri, Nissar A|Siddiqi, Mushtaq A
PMID: 22218684
Journal: Mol Cancer Ther. 2012 Mar;11(3):710-9.
Title: An integrated genomic approach to identify predictive biomarkers of response to the aurora kinase inhibitor PF-03814735.
Author: Hook, Kenneth E|Garza, Scott J|Lira, Maruja E|Ching, Keith A|Lee, Nathan V|Cao, Joan|Yuan, Jing|Ye, Jingjing|Ozeck, Mark|Shi, Stephanie T|Zheng, Xianxian|Rejto, Paul A|Kan, Julie L C|Christensen, James G|Pavlicek, Adam
PMID: 22222631
Journal: J Mol Med (Berl). 2012 Jun;90(6):707-18.
Title: Gastrin inhibits a novel, pathological colon cancer signaling pathway involving EGR1, AE2, and P-ERK.
Author: Song, Ling-Jun|Liu, Rui-Jun|Zeng, Zhi|Alper, Seth L|Cui, Heng-Jing|Lu, Yang|Zheng, Lin|Yan, Zhao-Wen|Fu, Guo-Hui
PMID: 22228178
Journal: World J Gastroenterol. 2012 Jan 7;18(1):70-8.
Title: Germline promoter hypermethylation of tumor suppressor genes in gastric cancer.
Author: Wu, Pu-Yuan|Zhang, Zheng|Wang, Jing-Mei|Guo, Wen-Wen|Xiao, Nong|He, Qiong|Wang, Ya-Ping|Fan, Yi-Mei
PMID: 22228973
Journal: Am J Gastroenterol. 2012 Mar;107(3):460-9.
Title: A novel pit pattern identifies the precursor of colorectal cancer derived from sessile serrated adenoma.
Author: Kimura, Tomoaki|Yamamoto, Eiichiro|Yamano, Hiro-O|Suzuki, Hiromu|Kamimae, Seiko|Nojima, Masanori|Sawada, Takeshi|Ashida, Masami|Yoshikawa, Kenjiro|Takagi, Ryo|Kato, Ryusuke|Harada, Taku|Suzuki, Ryo|Maruyama, Reo|Kai, Masahiro|Imai, Kohzoh|Shinomura, Yasuh
PMID: 22233696
Journal: Cancer Res. 2012 Mar 1;72(5):1301-15.
Title: Oncogenicity of the developmental transcription factor Sox9.
Author: Matheu, Ander|Collado, Manuel|Wise, Clare|Manterola, Lorea|Cekaite, Lina|Tye, Angela J|Canamero, Marta|Bujanda, Luis|Schedl, Andreas|Cheah, Kathryn S E|Skotheim, Rolf I|Lothe, Ragnhild A|Lopez de Munain, Adolfo|Briscoe, James|Serrano, Manuel|Lovell-Badge,
PMID: 22246670
Journal: Int J Mol Med. 2012 Apr;29(4):649-55.
Title: Oridonin induces apoptosis and senescence by increasing hydrogen peroxide and glutathione depletion in colorectal cancer cells.
Author: Gao, Feng-Hou|Liu, Feng|Wei, Wei|Liu, Li-Bin|Xu, Mang-Hua|Guo, Zhu-Ying|Li, Wei|Jiang, Bin|Wu, Ying-Li
PMID: 22294162
Journal: Methods Mol Biol. 2012;863:3-14.
Title: Epigenetic markers of early tumor development.
Author: Dumitrescu, Ramona G
PMID: 22359284
Journal: Hepatogastroenterology. 2012 Jun;59(116):1091-7.
Title: Correlations between clinicopathological parameters and molecular signatures of primary tumors for patients with stage T3n0 colorectal adenocarcinomas: a single center retrospective study on 100 cases.
Author: Andras, Csilla|Toth, Laszlo|Molnar, Csaba|Tanyi, Miklos|Csiki, Zoltan|Dezso, Balazs|Posan, Janos|Shemirani, Amir-Houshang|Csiki, Emese|Szanto, Janos
PMID: 22414548
Journal: Oncology. 2012;82(3):153-64.
Title: Differential expression of senescence and cell death factors in non-small cell lung and colorectal tumors showing telomere attrition.
Author: Fernandez-Marcelo, Tamara|Moran, Alberto|de Juan, Carmen|Pascua, Irene|Head, Jacqueline|Gomez, Ana|Hernando, Florentino|Lopez-Asenjo, Jose A|Hernandez, Susana|Sanchez-Pernaute, Andres|Torres, Antonio J|Benito, Manuel|Iniesta, Pilar
PMID: 22433385
Journal: Rev Esp Enferm Dig. 2012 Mar;104(3):111-7.
Title: p16 gene methylation in colorectal cancer patients with long-term follow-up.
Author: Veganzones-de-Castro, Silvia|Rafael-Fernandez, Sara|Vidaurreta-Lazaro, Marta|de-la-Orden, Virginia|Mediero-Valeros, Beatriz|Fernandez, Cristina|Maestro-de las Casas, Maria Luisa
PMID: 22449151
Journal: Am J Surg Pathol. 2012 Jul;36(7):1087-92.
Title: Detection of human papillomavirus in small cell carcinomas of the anus and rectum.
Author: Cimino-Mathews, Ashley|Sharma, Rajni|Illei, Peter B
PMID: 22531171
Journal: Nucleic Acids Res. 2012 Aug;40(15):7257-68. Epub 2012 May 17.
Title: Repetitive elements and enforced transcriptional repression co-operate to enhance DNA methylation spreading into a promoter CpG-island.
Author: Zhang, Yan|Shu, Jingmin|Si, Jiali|Shen, Lanlan|Estecio, Marcos R H|Issa, Jean-Pierre J
PMID: 22600741
Journal: Front Oncol. 2012 Feb 27;2:7.
Title: Stratification and Prognostic Relevance of Jass's Molecular Classification of Colorectal Cancer.
Author: Zlobec, Inti|Bihl, Michel P|Foerster, Anja|Rufle, Alex|Terracciano, Luigi|Lugli, Alessandro
PMID: 22655257
Journal: Clin Epigenetics. 2012 Jun 15;4(1):9.
Title: Hypermethylation of the 5' CpG island of the p14ARF flanking exon 1beta in human colorectal cancer displaying a restricted pattern of p53 overexpression concomitant with increased MDM2 expression.
Author: Nyiraneza, Christine|Sempoux, Christine|Detry, Roger|Kartheuser, Alex|Dahan, Karin
PMID: 22703554
Journal: Oncol Lett. 2012 Mar;3(3):565-570.
Title: PIK3CA mutation and methylation influences the outcome of colorectal cancer.
Author: Iida, Satoru|Kato, Shunsuke|Ishiguro, Megumi|Matsuyama, Takatoshi|Ishikawa, Toshiaki|Kobayashi, Hirotoshi|Higuchi, Tetsuro|Uetake, Hiroyuki|Enomoto, Masayuki|Sugihara, Kenichi
PMID: 22740953
Journal: J Prev Med Public Health. 2012 Jul;45(4):251-8.
Title: Quantitative analysis of cancer-associated gene methylation connected to risk factors in Korean colorectal cancer patients.
Author: Kang, Ho-Jin|Kim, Eun-Jeong|Kim, Byoung-Gwon|You, Chang-Hun|Lee, Sang-Yong|Kim, Dong-Il|Hong, Young-Seoub
PMID: 22880157
Journal: Toxicol Lett. 2012 Oct 2;214(1):1-8.
Title: Irinotecan induces senescence and apoptosis in colonic cells in vitro.
Author: Rudolf, Emil|John, Stanislav|Cervinka, Miroslav
PMID: 22898888
Journal: J Transl Med. 2012 Aug 27;10:173.
Title: Characterization of CDKN2A(p16) methylation and impact in colorectal cancer: systematic analysis using pyrosequencing.
Author: Bihl, Michel P|Foerster, Anja|Lugli, Alessandro|Zlobec, Inti
PMID: 22925370
Journal: Hered Cancer Clin Pract. 2012 Aug 29;10(1):11.
Title: Novel germline CDK4 mutations in patients with head and neck cancer.
Author: Sabir, Maimoona|Baig, Ruqia Mehmood|Mahjabeen, Ishrat|Kayani, Mahmood Akhtar
PMID: 22932448
Journal: Cancer Genet. 2012 Oct;205(10):501-7.
Title: Association of polymorphisms in microRNA-binding sites and colorectal cancer in an Iranian population.
Author: Azimzadeh, Pedram|Romani, Sara|Mohebbi, Seyed Reza|Mahmoudi, Touraj|Vahedi, Mohsen|Fatemi, Seyed Reza|Zali, Narges|Zali, Mohammad Reza
PMID: 22939228
Journal: Cancer Cell. 2012 Sep 11;22(3):318-30.
Title: EGF receptor signaling is essential for k-ras oncogene-driven pancreatic ductal adenocarcinoma.
Author: Navas, Carolina|Hernandez-Porras, Isabel|Schuhmacher, Alberto J|Sibilia, Maria|Guerra, Carmen|Barbacid, Mariano
PMID: 22975375
Journal: Cancer Res. 2012 Nov 15;72(22):5900-11.
Title: Inactivation of the Dlc1 gene cooperates with downregulation of p15INK4b and p16Ink4a, leading to neoplastic transformation and poor prognosis in human cancer.
Author: Qian, Xiaolan|Durkin, Marian E|Wang, Dunrui|Tripathi, Brajendra K|Olson, Lyra|Yang, Xu-Yu|Vass, William C|Popescu, Nicholas C|Lowy, Douglas R
PMID: 23010077
Journal: Cancer Epidemiol Biomarkers Prev. 2012 Nov;21(11):2069-75.
Title: Methylation of the polycomb group target genes is a possible biomarker for favorable prognosis in colorectal cancer.
Author: Dallol, Ashraf|Al-Maghrabi, Jaudah|Buhmeida, Abdelbaset|Gari, Mamdooh A|Chaudhary, Adeel G|Schulten, Hans-Juergen|Abuzenadah, Adel M|Al-Ahwal, Mahmoud S|Sibiany, Abdulrahman|Al-Qahtani, Mohammed H
PMID: 23010642
Journal: Oncol Rep. 2012 Dec;28(6):1997-2002.
Title: UHRF1 expression is upregulated and associated with cellular proliferation in colorectal cancer.
Author: Kofunato, Yasuhide|Kumamoto, Kensuke|Saitou, Katsuharu|Hayase, Suguru|Okayama, Hirokazu|Miyamoto, Kotaro|Sato, Yu|Katakura, Kyoko|Nakamura, Izumi|Ohki, Shinji|Koyama, Yoshihisa|Unoki, Motoko|Takenoshita, Seiichi
PMID: 23023523
Journal: Exp Ther Med. 2012 Nov;4(5):865-870.
Title: Promoter and histone methylation and p16(INK4A) gene expression in colon cancer.
Author: Yoruker, Ebru Esin|Mert, Ufuk|Bugra, Dursun|Yamaner, Sumer|Dalay, Nejat
PMID: 23226740
Journal: Cancer. 2013 Jan 15;119(2):266-76.
Title: Genetic and epigenetic alterations in primary colorectal cancers and related lymph node and liver metastases.
Author: Miranda, Elena|Bianchi, Paolo|Destro, Annarita|Morenghi, Emanuela|Malesci, Alberto|Santoro, Armando|Laghi, Luigi|Roncalli, Massimo
PMID: 22786759
Journal: Eur J Nutr. 2013 Jun;52(4):1327-41.
Title: Colorectal cancer cells Caco-2 and HCT116 resist epigenetic effects of isothiocyanates and selenium in vitro.
Author: Barrera, Lawrence N|Johnson, Ian T|Bao, Yongping|Cassidy, Aedin|Belshaw, Nigel J
PMID: 22923034
Journal: Int J Cancer. 2013 May 1;132(9):2209-16.
Title: Methylation and microsatellite status and recurrence following adjuvant FOLFOX in colorectal cancer.
Author: Han, Sae-Won|Lee, Hyun-Jung|Bae, Jeong Mo|Cho, Nam-Yun|Lee, Kyung-Hun|Kim, Tae-Yong|Oh, Do-Youn|Im, Seock-Ah|Bang, Yung-Jue|Jeong, Seung-Yong|Park, Kyu Joo|Park, Jae-Gahb|Kang, Gyeong Hoon|Kim, Tae-You
PMID: 23034738
Journal: Int J Oncol. 2013 Jan;42(1):127-33.
Title: DNA methylation of the p14ARF, RASSF1A and APC1A genes as an independent prognostic factor in colorectal cancer patients.
Author: Nilsson, Torbjorn K|Lof-Ohlin, Zarah M|Sun, Xiao-Feng
PMID: 23128528
Journal: Biosens Bioelectron. 2013 Apr 15;42:503-11.
Title: A novel bisulfite-microfluidic temperature gradient capillary electrophoresis platform for highly sensitive detection of gene promoter methylation.
Author: Zhang, Huidan|Shan, Lianfeng|Wang, Xiaonan|Ma, Qian|Fang, Jin
PMID: 23246658
Journal: Mol Biol Rep. 2013 May;40(5):3851-7.
Title: Different patterns of DNA methylation of the two distinct O6-methylguanine-DNA methyltransferase (O6-MGMT) promoter regions in colorectal cancer.
Author: Mokarram, P|Zamani, M|Kavousipour, S|Naghibalhossaini, F|Irajie, C|Moradi Sarabi, M|Hosseini, S V
PMID: 23271133
Journal: Cancer. 2013 May 1;119(9):1752-60.
Title: Cohypermethylation of p14 in combination with CADM1 or DCC as a recurrence-related prognostic indicator in stage I esophageal squamous cell carcinoma.
Author: Lee, Eunju|Lee, Bo Bin|Ko, Eunkyung|Kim, Yujin|Han, Jungho|Shim, Young Mog|Park, Joobae|Kim, Duk-Hwan
PMID: 23310950
Journal: PLoS One. 2013;8(1):e52501.
Title: Comparison study of MS-HRM and pyrosequencing techniques for quantification of APC and CDKN2A gene methylation.
Author: Migheli, Francesca|Stoccoro, Andrea|Coppede, Fabio|Wan Omar, Wan Adnan|Failli, Alessandra|Consolini, Rita|Seccia, Massimo|Spisni, Roberto|Miccoli, Paolo|Mathers, John C|Migliore, Lucia
PMID: 23326336
Journal: Int J Oncol. 2013 Apr;42(4):1212-8.
Title: Depletion of JARID1B induces cellular senescence in human colorectal cancer.
Author: Ohta, Katsuya|Haraguchi, Naotsugu|Kano, Yoshihiro|Kagawa, Yoshinori|Konno, Masamitsu|Nishikawa, Shimpei|Hamabe, Atsushi|Hasegawa, Shinichiro|Ogawa, Hisataka|Fukusumi, Takahito|Uemura, Mamoru|Nishimura, Junichi|Hata, Taishi|Takemasa, Ichiro|Mizushima, Tsun
PMID: 23354547
Journal: Br J Cancer. 2013 Apr 2;108(6):1378-86.
Title: Common genetic variants in the 9p21 region and their associations with multiple tumours.
Author: Gu, F|Pfeiffer, R M|Bhattacharjee, S|Han, S S|Taylor, P R|Berndt, S|Yang, H|Sigurdson, A J|Toro, J|Mirabello, L|Greene, M H|Freedman, N D|Abnet, C C|Dawsey, S M|Hu, N|Qiao, Y-L|Ding, T|Brenner, A V|Garcia-Closas, M|Hayes, R|Brinton, L A|Lissowska, J|Wentz
PMID: 23361049
Journal: Nutr Cancer. 2013;65(1):118-25.
Title: Black raspberry-derived anthocyanins demethylate tumor suppressor genes through the inhibition of DNMT1 and DNMT3B in colon cancer cells.
Author: Wang, Li-Shu|Kuo, Chieh-Ti|Cho, Seung-Ju|Seguin, Claire|Siddiqui, Jibran|Stoner, Kristen|Weng, Yu-I|Huang, Tim H-M|Tichelaar, Jay|Yearsley, Martha|Stoner, Gary D|Huang, Yi-Wen
PMID: 23368921
Journal: Food Funct. 2013 Apr 25;4(4):575-85.
Title: Boletus edulis biologically active biopolymers induce cell cycle arrest in human colon adenocarcinoma cells.
Author: Lemieszek, Marta Kinga|Cardoso, Claudia|Ferreira Milheiro Nunes, Fernando Herminio|Ramos Novo Amorim de Barros, Ana Isabel|Marques, Guilhermina|Pozarowski, Piotr|Rzeski, Wojciech
PMID: 23370594
Journal: PLoS One. 2013;8(2):e57172.
Title: Autophagy and cellular senescence mediated by Sox2 suppress malignancy of cancer cells.
Author: Cho, Yong-Yeon|Kim, Dong Joon|Lee, Hye Suk|Jeong, Chul-Ho|Cho, Eun-Jin|Kim, Myong-Ok|Byun, Sanguine|Lee, Kun-Yeong|Yao, Ke|Carper, Andria|Langfald, Alyssa|Bode, Ann M|Dong, Zigang
PMID: 23451179
Journal: PLoS One. 2013;8(3):e58731.
Title: Somatic mutations, allele loss, and DNA methylation of the Cub and Sushi Multiple Domains 1 (CSMD1) gene reveals association with early age of diagnosis in colorectal cancer patients.
Author: Shull, Austin Y|Clendenning, Megan L|Ghoshal-Gupta, Sampa|Farrell, Christopher L|Vangapandu, Hima V|Dudas, Larry|Wilkerson, Brent J|Buckhaults, Phillip J
PMID: 23505554
Journal: Br J Cancer. 2013 Jun 25;108(12):2542-8.
Title: The prognostic value of CDKN2A hypermethylation in colorectal cancer: a meta-analysis.
Author: Xing, X|Cai, W|Shi, H|Wang, Y|Li, M|Jiao, J|Chen, M
PMID: 23703248
Journal: BMC Complement Altern Med. 2013 Jun 8;13:128.
Title: Teng-Long-Bu-Zhong-Tang, a Chinese herbal formula, enhances anticancer effects of 5--Fluorouracil in CT26 colon carcinoma.
Author: Deng, Shan|Hu, Bing|An, Hong-Mei|Du, Qin|Xu, Ling|Shen, Ke-Ping|Shi, Xiu-Feng|Wei, Meng-Meng|Wu, Yang
PMID: 23758730
Journal: DNA Cell Biol. 2013 Jul;32(7):400-8.
Title: Do CDKN2 p16 540 C>G, CDKN2 p16 580 C>T, and MDM2 SNP309 T>G gene variants act on colorectal cancer development or progression?
Author: Tuna, Gulay|Kucukhuseyin, Ozlem|Arikan, Soykan|Kaytan Saglam, Esra|Guler, Erkan|Cacina, Canan|Oztop, Ozge|Turan, Saime|Korkmaz, Gurbet|Yaylim, Ilhan
PMID: 23777425
Journal: PLoS One. 2013 Jun 21;8(6):e66587.
Title: The Prognostic Value of p16 Hypermethylation in Cancer: A Meta-Analysis.
Author: Xing, Xiang-Bin|Cai, Wei-Bin|Luo, Liang|Liu, Long-Shan|Shi, Hui-Juan|Chen, Min-Hu
PMID: 23805242
Journal: J Biol Regul Homeost Agents. 2013 Apr-Jun;27(2):297-307.
Title: Methylation profile of promoter region of p16 gene in colorectal cancer patients of Kashmir valley.
Author: Wani, H A|Beigh, M A|Amin, S|Bhat, A A|Bhat, S|Khan, H|Mattoo, A A|Showkat, M|Masood, A|Majid, S
PMID: 23830381
Journal: Cancer Cell. 2013 Jul 8;24(1):1-2.
Title: BRAF: a driver of the serrated pathway in colon cancer.
Author: Rustgi, Anil K
PMID: 23845435
Journal: Br J Cancer. 2013 Oct 15;109(8):2207-16.
Title: The in situ local immune response, tumour senescence and proliferation in colorectal cancer.
Author: Roxburgh, C S|Richards, C H|Macdonald, A I|Powell, A G|McGlynn, L M|McMillan, D C|Horgan, P G|Edwards, J|Shiels, P G
PMID: 24022192
Journal: Mol Biol Rep. 2013 Nov;40(11):6351-61.
Title: Expression of cell cycle regulatory factors hus1, gadd45a, rb1, cdkn2a and mre11a correlates with expression of clock gene per2 in human colorectal carcinoma tissue.
Author: Storcelova, Maria|Vician, Marian|Reis, Richard|Zeman, Michal|Herichova, Iveta
PMID: 24062075
Journal: J Clin Endocrinol Metab. 2013 Dec;98(12):E1909-17.
Title: Shikonin inhibits thyroid cancer cell growth and invasiveness through targeting major signaling pathways.
Author: Yang, Qi|Ji, Meiju|Guan, Haixia|Shi, Bingyin|Hou, Peng
PMID: 24106286
Journal: Genet Mol Biol. 2013 Sep;36(3):323-8.
Title: Predicting the progress of colon cancer by DNA methylation markers of the p16 gene in feces - Evidence from an animal model.
Author: Wu, Wen-Chih|Hsu, Chih-Hsiung|Kuan, Jen-Chun|Hsieh, Jih-Fu|Sun, Chien-An|Yang, Tsan|Wu, Chang-Chieh|Chou, Yu-Ching
PMID: 24130437
Journal: Exp Ther Med. 2013 Nov;6(5):1225-1228.
Title: Effects of iodine-125 seeds on the methylation of SFRP2 and P16 in colorectal cancer.
Author: Li, Xiaogang|Lu, Ping|Li, Bo|Zhang, Wangfu|Luo, Kaiyuan
PMID: 24223648
Journal: Oncol Lett. 2013 Dec;6(6):1687-1692.
Title: DNA methylation as an epigenetic biomarker in colorectal cancer.
Author: Silva, Tiago Donizetti|Vidigal, Veronica Marques|Felipe, Aledson Vitor|DE Lima, Jacqueline Miranda|Neto, Ricardo Artigiani|Saad, Sarhan Sidney|Forones, Nora Manoukian
PMID: 24260063
Journal: Cancer Gene Ther. 2013 Dec;20(12):690-4.
Title: S-phase kinase-associated protein 2 knockdown blocks colorectal cancer growth via regulation of both p27 and p16 expression.
Author: Xu, S-Y|Wang, F|Wei, G|Wang, B|Yang, J-Y|Huang, Y-Z|Zhang, L|Zheng, F|Guo, L-Y|Wang, J-N|Tang, J-M
PMID: 24336114
Journal: Tumour Biol. 2014 Feb;35(2):1439-49.
Title: Biological significance of promoter hypermethylation of p14/ARF gene: relationships to p53 mutational status in Tunisian population with colorectal carcinoma.
Author: Chaar, Ines|Amara, Sameh|Elamine, Olfa Elhadj|Khiari, Mariem|Ounissi, Donia|Khalfallah, Taher|Ben Hmida, Abdelmajid|Mzabi, Sabeh|Bouraoui, Saadia
PMID: 24065196
Journal: Int J Cancer. 2014 Jun 15;134(12):2820-8.
Title: KRAS mutations and CDKN2A promoter methylation show an interactive adverse effect on survival and predict recurrence of rectal cancer.
Author: Kohonen-Corish, Maija R J|Tseung, Jason|Chan, Charles|Currey, Nicola|Dent, Owen F|Clarke, Stephen|Bokey, Les|Chapuis, Pierre H
PMID: 24259266
Journal: Cancer Invest. 2014 Feb;32(2):43-52.
Title: Prognostic value of p16 promoter hypermethylation in colorectal cancer: a meta-analysis.
Author: Jiang, Wenjie|Wang, Pei-Ge|Zhan, Yuzhu|Zhang, Dongfeng
PMID: 24410593
Journal: PLoS One. 2014 Jan 21;9(1):e86657.
Title: Comparison of CpG island methylator phenotype (CIMP) frequency in colon cancer using different probe- and gene-specific scoring alternatives on recommended multi-gene panels.
Author: Berg, Marianne|Hagland, Hanne R|Soreide, Kjetil
PMID: 24466191
Journal: PLoS One. 2014 Jan 27;9(1):e82185.
Title: An integrative CGH, MSI and candidate genes methylation analysis of colorectal tumors.
Author: Brim, Hassan|Abu-Asab, Mones S|Nouraie, Mehdi|Salazar, Jose|Deleo, Jim|Razjouyan, Hadi|Mokarram, Pooneh|Schaffer, Alejandro A|Naghibhossaini, Fakhraddin|Ashktorab, Hassan
PMID: 24475022
Journal: J Pineal Res. 2014 Apr;56(3):264-74.
Title: Melatonin treatment induces interplay of apoptosis, autophagy, and senescence in human colorectal cancer cells.
Author: Hong, Yunkyung|Won, Jinyoung|Lee, Youngjeon|Lee, Seunghoon|Park, Kanghui|Chang, Kyu-Tae|Hong, Yonggeun
PMID: 24484372
Journal: Epigenetics. 2014 Apr;9(4):621-33.
Title: Gene promoter methylation in colorectal cancer and healthy adjacent mucosa specimens: correlation with physiological and pathological characteristics, and with biomarkers of one-carbon metabolism.
Author: Coppede, Fabio|Migheli, Francesca|Lopomo, Angela|Failli, Alessandra|Legitimo, Annalisa|Consolini, Rita|Fontanini, Gabriella|Sensi, Elisa|Servadio, Adele|Seccia, Massimo|Zocco, Giuseppe|Chiarugi, Massimo|Spisni, Roberto|Migliore, Lucia
PMID: 24500500
Journal: J Environ Sci Health B. 2014;49(4):279-89.
Title: Effect of 2-amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine on oxidative stress and gene expression of c-fos, c-jun, p16 and Rb in rat colons and protective role of seabuckthorn seed oil.
Author: Li, Rui Jin|Tian, Jing Jing|Li, Wan Qing|Cheng, Fang Qin|Gao, Gang Shuan
PMID: 24502215
Journal: Epigenetics. 2014 May;9(5):738-46.
Title: CpG island methylator phenotype and its association with malignancy in sporadic duodenal adenomas.
Author: Sun, Lifeng|Guzzetta, Angela A|Fu, Tao|Chen, Jinming|Jeschke, Jana|Kwak, Ruby|Vatapalli, Rajita|Baylin, Stephen B|Iacobuzio-Donahue, Christine A|Wolfgang, Christopher L|Ahuja, Nita
PMID: 24518818
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2014 Jan;17(1):31-5.
Title: [Proliferative and invasive effects of inhibitors of kinase 4(P15(ink4b) and P16(ink4a)/CDKN2) gene activation on RKO human colorectal cancer cells].
Author: Fang, Xiaoming|Jiang, Zhaohui|Peng, Jiaping|Yao, Ning|Fang, Xudong|Zheng, Shu
PMID: 24519046
Journal: BMC Genomics. 2014 Mar 13;15:190.
Title: Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma.
Author: Castle, John C|Loewer, Martin|Boegel, Sebastian|de Graaf, Jos|Bender, Christian|Tadmor, Arbel D|Boisguerin, Valesca|Bukur, Thomas|Sorn, Patrick|Paret, Claudia|Diken, Mustafa|Kreiter, Sebastian|Tureci, Ozlem|Sahin, Ugur
PMID: 24621249
Journal: Elife. 2014 Mar 12;3:e02313.
Title: A KRAS-directed transcriptional silencing pathway that mediates the CpG island methylator phenotype.
Author: Serra, Ryan W|Fang, Minggang|Park, Sung Mi|Hutchinson, Lloyd|Green, Michael R
PMID: 24623306
Journal: Neuro Oncol. 2014 Oct;16(10):1333-40.
Title: Germline rearrangements in families with strong family history of glioma and malignant melanoma, colon, and breast cancer.
Author: Andersson, Ulrika|Wibom, Carl|Cederquist, Kristina|Aradottir, Steina|Borg, Ake|Armstrong, Georgina N|Shete, Sanjay|Lau, Ching C|Bainbridge, Matthew N|Claus, Elizabeth B|Barnholtz-Sloan, Jill|Lai, Rose|Il'yasova, Dora|Houlston, Richard S|Schildkraut, Joell
PMID: 24723567
Journal: J Clin Pathol. 2014 Jul;67(7):592-8.
Title: Loss of p16(INK4a) is associated with reduced patient survival in soft tissue tumours, and indicates a senescence barrier.
Author: Knosel, Thomas|Altendorf-Hofmann, Annelore|Lindner, Lars|Issels, Rolf|Hermeking, Heiko|Schuebbe, Gesa|Gibis, Sebastian|Siemens, Helge|Kampmann, Eric|Kirchner, Thomas
PMID: 24747207
Journal: Gastroenterol Res Pract. 2014;2014:436985.
Title: Prognostic and predictive value of CpG island methylator phenotype in patients with locally advanced nonmetastatic sporadic colorectal cancer.
Author: Wang, Yuwei|Long, Yadong|Xu, Ye|Guan, Zuqing|Lian, Peng|Peng, Junjie|Cai, Sanjun|Cai, Guoxiang
PMID: 24822060
Journal: Tumour Biol. 2014 Aug;35(8):7877-85.
Title: Limoniastrum guyonianum aqueous gall extract induces apoptosis in colorectal cancer cells by inhibiting calpain activity.
Author: Krifa, Mounira|Pizzi, Antonio|Mousli, Marc|Chekir-Ghedira, Leila|Leloup, Ludovic|Ghedira, Kamel
PMID: 24828012
Journal: Tumour Biol. 2014 Aug;35(8):8267-79.
Title: The specific methylation characteristics of cancer related genes in Chinese colorectal cancer patients.
Author: Yang, WenJie|Wang, XiaoFeng|Li, XiaoWei|Wang, Min|Chen, XiaoFeng|Wu, XiaoMei|Wang, YaPing|Fan, YiMei|Jin, HeiYing
PMID: 24852431
Journal: Hepatogastroenterology. 2014 Mar-Apr;61(130):354-6.
Title: p16 Methylation is frequently detected in the serum of metastatic colorectal cancer patients.
Author: Hibi, Kenji|Mizukami, Hiroki|Saito, Mitsuo|Kigawa, Gaku|Nemoto, Hiroshi
PMID: 24901139
Journal: Biochem Biophys Res Commun. 2014 Jul 18;450(1):652-8.
Title: Anti-proliferative and pro-apoptotic activity of whole extract and isolated indicaxanthin from Opuntia ficus-indica associated with re-activation of the onco-suppressor p16(INK4a) gene in human colorectal carcinoma (Caco-2) cells.
Author: Naselli, Flores|Tesoriere, Luisa|Caradonna, Fabio|Bellavia, Daniele|Attanzio, Alessandro|Gentile, Carla|Livrea, Maria A
PMID: 24937448
Journal: DNA Cell Biol. 2014 Oct;33(10):729-38.
Title: Relationships between p16 gene promoter methylation and clinicopathologic features of colorectal cancer: a meta-analysis of 27 cohort studies.
Author: Chen, Yan-Zhi|Liu, Dan|Zhao, Yu-Xia|Wang, He-Tong|Gao, Ya|Chen, Ying
PMID: 24979649
Journal: Inflamm Bowel Dis. 2014 Sep;20(9):1584-92.
Title: Small bowel adenocarcinomas complicating Crohn's disease are associated with dysplasia: a pathological and molecular study.
Author: Svrcek, Magali|Piton, Gael|Cosnes, Jacques|Beaugerie, Laurent|Vermeire, Severine|Geboes, Karel|Lemoine, Antoinette|Cervera, Pascale|El-Murr, Nizar|Dumont, Sylvie|Scriva, Aurelie|Lascols, Olivier|Ardizzone, Sandro|Fociani, Paolo|Savoye, Guillaume|Le Pessot
PMID: 25029614
Journal: Biochem Cell Biol. 2014 Aug;92(4):305-15.
Title: Involvement of ERK1/2, p38 MAPK, and PI3K/Akt signaling pathways in the regulation of cell cycle progression by PTHrP in colon adenocarcinoma cells.
Author: Calvo, Natalia|Martin, Maria Julia|de Boland, Ana Russo|Gentili, Claudia
PMID: 25051885
Journal: J Am Acad Dermatol. 2014 Nov;71(5):888-95.
Title: Increased prevalence of lung, breast, and pancreatic cancers in addition to melanoma risk in families bearing the cyclin-dependent kinase inhibitor 2A mutation: implications for genetic counseling.
Author: Potrony, Miriam|Puig-Butille, Joan Anton|Aguilera, Paula|Badenas, Celia|Carrera, Cristina|Malvehy, Josep|Puig, Susana
PMID: 25064638
Journal: Int J Med Sci. 2014 Jul 2;11(9):936-47.
Title: Potential dual immunomodulatory role of VEGF in ulcerative colitis and colorectal carcinoma.
Author: Zdravkovic, Natasa D|Jovanovic, Ivan P|Radosavljevic, Gordana D|Arsenijevic, Aleksandar N|Zdravkovic, Nebojsa D|Mitrovic, Slobodanka Lj|Arsenijevic, Nebojsa N
PMID: 25076849
Journal: Nutr Cancer. 2014;66(7):1220-7.
Title: Luteolin induces apoptosis in BE colorectal cancer cells by downregulating calpain, UHRF1, and DNMT1 expressions.
Author: Krifa, Mounira|Leloup, Ludovic|Ghedira, Kamel|Mousli, Marc|Chekir-Ghedira, Leila
PMID: 25207720
Journal: Am J Physiol Regul Integr Comp Physiol. 2014 Dec 15;307(12):R1413-27.
Title: Effects of metabolic acidosis on intracellular pH responses in multiple cell types.
Author: Salameh, Ahlam Ibrahim|Ruffin, Vernon A|Boron, Walter F
PMID: 25209413
Journal: Biomed Res Int. 2014;2014:236361.
Title: CpG island methylator phenotype and prognosis of colorectal cancer in Northeast China.
Author: Li, Xia|Hu, Fulan|Wang, Yibaina|Yao, Xiaoping|Zhang, Zuoming|Wang, Fan|Sun, Guizhi|Cui, Bin-Bin|Dong, Xinshu|Zhao, Yashuang
PMID: 25243122
Journal: Hum Pathol. 2014 Nov;45(11):2334-40.
Title: High-mobility group AT-hook 2: an independent marker of poor prognosis in intrahepatic cholangiocarcinoma.
Author: Lee, Chung-Ta|Wu, Tsung-Teh|Lohse, Christine M|Zhang, Lizhi
PMID: 25245603
Journal: Sci Signal. 2014 Sep 30;7(345):ra92.
Title: Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-beta-catenin-mediated intestinal tumor growth and regeneration.
Author: Phesse, Toby J|Buchert, Michael|Stuart, Emma|Flanagan, Dustin J|Faux, Maree|Afshar-Sterle, Shoukat|Walker, Francesca|Zhang, Hui-Hua|Nowell, Cameron J|Jorissen, Robert|Tan, Chin Wee|Hirokawa, Yumiko|Eissmann, Moritz F|Poh, Ashleigh R|Malaterre, Jordane|Pea
PMID: 25270258
Journal: Oncotarget. 2014 Nov 15;5(21):10778-90.
Title: Paradoxical role of CBX8 in proliferation and metastasis of colorectal cancer.
Author: Tang, Jianjun|Wang, Gang|Zhang, Meifang|Li, Feng-yan|Sang, Yi|Wang, Boqing|Hu, Kaishun|Wu, Yuanzhong|Luo, Rongzhen|Liao, Dan|Cao, Jingying|Wang, Xin|Wang, Li|Zhang, Ruhua|Zhang, Xiaoshi|Deng, Wu-guo|Xie, Dan|Xu, Rui-hua|Kang, Tiebang
PMID: 25360999
Journal: Med Oncol. 2014 Dec;31(12):288.
Title: Pokemon enhances proliferation, cell cycle progression and anti-apoptosis activity of colorectal cancer independently of p14ARF-MDM2-p53 pathway.
Author: Zhao, Yi|Yao, Yun-hong|Li, Li|An, Wei-fang|Chen, Hong-zen|Sun, Li-ping|Kang, Hai-xian|Wang, Sen|Hu, Xin-rong
PMID: 25367850
Journal: ScientificWorldJournal. 2014;2014:129697.
Title: Achyranthes aspera root extracts induce human colon cancer cell (COLO-205) death by triggering the mitochondrial apoptosis pathway and S phase cell cycle arrest.
Author: Arora, Shagun|Tandon, Simran
PMID: 25401123
Journal: Mod Pathol. 2015 Mar;28(3):414-27.
Title: A clinicopathological and molecular analysis of 200 traditional serrated adenomas.
Author: Bettington, Mark L|Walker, Neal I|Rosty, Christophe|Brown, Ian S|Clouston, Andrew D|McKeone, Diane M|Pearson, Sally-Ann|Klein, Kerenaftali|Leggett, Barbara A|Whitehall, Vicki L J
PMID: 25216220
Journal: Ann Surg Oncol. 2015 Dec;22 Suppl 3:S1394-401.
Title: A Cancer Reprogramming Method Using MicroRNAs as a Novel Therapeutic Approach against Colon Cancer: Research for Reprogramming of Cancer Cells by MicroRNAs.
Author: Miyazaki, Susumu|Yamamoto, Hirofumi|Miyoshi, Norikatsu|Wu, Xin|Ogawa, Hisataka|Uemura, Mamoru|Nishimura, Junichi|Hata, Taishi|Takemasa, Ichiro|Mizushima, Tsunekazu|Konno, Masamitsu|Doki, Yuichiro|Mori, Masaki|Ishii, Hideshi
PMID: 25384704
Journal: Mol Carcinog. 2015 Dec;54(12):1786-95.
Title: Rectal cancer profiling identifies distinct subtypes in India based on age at onset, genetic, epigenetic and clinicopathological characteristics.
Author: Laskar, Ruhina Shirin|Ghosh, Sankar Kumar|Talukdar, Fazlur Rahman
PMID: 25418895
Journal: Pathol Res Pract. 2015 Jan;211(1):78-82.
Title: Sebaceous neoplasms and the immunoprofile of mismatch-repair proteins as a screening target for syndromic cases.
Author: Boennelycke, Marie|Thomsen, Birthe M|Holck, Susanne
PMID: 25457183
Journal: Gastroenterology. 2015 Mar;148(3):556-64.
Title: Prevalence of germline mutations in cancer predisposition genes in patients with pancreatic cancer.
Author: Grant, Robert C|Selander, Iris|Connor, Ashton A|Selvarajah, Shamini|Borgida, Ayelet|Briollais, Laurent|Petersen, Gloria M|Lerner-Ellis, Jordan|Holter, Spring|Gallinger, Steven
PMID: 25479140
Journal: Tumour Biol. 2015 May;36(5):3853-61.
Title: Combined methylation of p16 and hMLH1 (CMETH2) discriminates a subpopulation with better prognosis in colorectal cancer patients with microsatellite instability tumors.
Author: Veganzones, S|Maestro, M L|Rafael, S|de la Orden, V|Vidaurreta, M|Mediero, B|Espantaleon, M|Cerdan, J|Diaz-Rubio, E
PMID: 25576161
Journal: Digestion. 2015;91(1):57-63.
Title: Clinicopathological and molecular characteristics of serrated lesions in Japanese elderly patients.
Author: Nosho, Katsuhiko|Igarashi, Hisayoshi|Ito, Miki|Mitsuhashi, Kei|Kurihara, Hiroyoshi|Kanno, Shinichi|Yoshii, Shinji|Mikami, Masashi|Takahashi, Hiroaki|Kusumi, Takaya|Hosokawa, Masao|Sukawa, Yasutaka|Adachi, Yasushi|Hasegawa, Tadashi|Okita, Kenji|Hirata, Koi
PMID: 25632919
Journal: Tumour Biol. 2015 Jun;36(6):4661-70.
Title: Association of HPV with genetic and epigenetic alterations in colorectal adenocarcinoma from Indian population.
Author: Laskar, Ruhina S|Talukdar, Fazlur R|Choudhury, Javed H|Singh, Seram Anil|Kundu, Sharbadeb|Dhar, Bishal|Mondal, Rosy|Ghosh, Sankar Kumar
PMID: 25647260
Journal: Ophthalmic Genet. 2015 Jun;36(2):126-31.
Title: Analysis of BAP1 Germline Gene Mutation in Young Uveal Melanoma Patients.
Author: Cebulla, Colleen M|Binkley, Elaine M|Pilarski, Robert|Massengill, James B|Rai, Karan|Liebner, David A|Marino, Meghan J|Singh, Arun D|Abdel-Rahman, Mohamed H
PMID: 25687217
Journal: Cell Cycle. 2015;14(8):1252-9.
Title: Cyclin-dependent kinase pathway aberrations in diverse malignancies: clinical and molecular characteristics.
Author: Kato, Shumei|Schwaederle, Maria|Daniels, Gregory A|Piccioni, David|Kesari, Santosh|Bazhenova, Lyudmila|Shimabukuro, Kelly|Parker, Barbara A|Fanta, Paul|Kurzrock, Razelle
PMID: 25695927
Journal: Oncol Res. 2015;22(2):93-103.
Title: RNA interference of Biot2 induces G1 phase arrest and apoptosis in mouse colorectal cancer cell line.
Author: Zhou, Cong|Zhang, Peng|Xu, Guang-Chao|Wu, Dong-Ming|Liu, Ru-Yan|Zeng, Qi|Wang, Chun-Ting
PMID: 25706396
Journal: PLoS One. 2015 Mar 27;10(3):e0123396.
Title: DNA methylation combinations in adjacent normal colon tissue predict cancer recurrence: evidence from a clinical cohort study.
Author: Kuan, Jen Chun|Wu, Chang Chieh|Sun, Chien An|Chu, Chi Ming|Lin, Fu Gong|Hsu, Chih Hsiung|Kan, Po-Chieh|Lin, Shih-Chieh|Yang, Tsan|Chou, Yu-Ching
PMID: 25815725
Journal: Contemp Clin Trials. 2015 May;42:90-7.
Title: Self-directed physical activity intervention in older adults undergoing adjuvant chemotherapy for colorectal cancer: Design of a randomized controlled trial.
Author: Williams, Grant R|Nyrop, Kirsten A|Deal, Allison M|Muss, Hyman B|Sanoff, Hanna K
PMID: 25827253
Journal: J Surg Res. 2015 Jul;197(1):85-90.
Title: Treatment of peritoneal carcinomatosis with intraperitoneal administration of Ad-hARF.
Author: Rajeshkumar, Barur R|Paliwal, Seema|Lambert, Laura|Grossman, Steven R|Whalen, Giles F
PMID: 25935465
Journal: Epigenomics. 2015;7(2):175-86.
Title: Application of artificial neural networks to link genetic and environmental factors to DNA methylation in colorectal cancer.
Author: Coppede, Fabio|Grossi, Enzo|Lopomo, Angela|Spisni, Roberto|Buscema, Massimo|Migliore, Lucia
PMID: 25942531
Journal: Arch Iran Med. 2015 May;18(5):284-95.
Title: Mushroom Extracts Induce Human Colon Cancer Cell (COLO-205) Death by Triggering the Mitochondrial Apoptosis Pathway and Go/G1-Phase Cell Cycle Arrest.
Author: Arora, Shagun|Tandon, Simran
PMID: 25959910
Journal: Int J Clin Exp Pathol. 2015 Feb 1;8(2):1920-8. eCollection 2015.
Title: Nuclear maspin expression correlates with the CpG island methylator phenotype and tumor aggressiveness in colorectal cancer.
Author: Kim, Jung Ho|Cho, Nam-Yun|Bae, Jeong Mo|Kim, Kyung-Ju|Rhee, Ye-Young|Lee, Hye Seung|Kang, Gyeong Hoon
PMID: 25973084
Journal: Hum Pathol. 2015 Jul;46(7):933-8.
Title: Traditional serrated adenoma: an update.
Author: Bettington, Mark L|Chetty, Runjan
PMID: 26001333
Journal: Clin Epigenetics. 2015 Jul 9;7:63.
Title: Different prognostic effect of CpG island methylation according to sex in colorectal cancer patients treated with adjuvant FOLFOX.
Author: Lee, Dae-Won|Han, Sae-Won|Cha, Yongjun|Rhee, Ye Young|Bae, Jeong Mo|Cho, Nam-Yun|Lee, Kyung-Hun|Kim, Tae-Yong|Oh, Do-Youn|Im, Seock-Ah|Bang, Yung-Jue|Jeong, Seung-Yong|Park, Kyu Joo|Kang, Gyeong Hoon|Kim, Tae-You
PMID: 26157509
Journal: Fam Cancer. 2015 Dec;14(4):621-8.
Title: POLE mutations in families predisposed to cutaneous melanoma.
Author: Aoude, Lauren G|Heitzer, Ellen|Johansson, Peter|Gartside, Michael|Wadt, Karin|Pritchard, Antonia L|Palmer, Jane M|Symmons, Judith|Gerdes, Anne-Marie|Montgomery, Grant W|Martin, Nicholas G|Tomlinson, Ian|Kearsey, Stephen|Hayward, Nicholas K
PMID: 26251183
Journal: Br J Cancer. 2015 Sep 29;113(7):1035-45.
Title: Potential of DNA methylation in rectal cancer as diagnostic and prognostic biomarkers.
Author: Exner, Ruth|Pulverer, Walter|Diem, Martina|Spaller, Lisa|Woltering, Laura|Schreiber, Martin|Wolf, Brigitte|Sonntagbauer, Markus|Schroder, Fabian|Stift, Judith|Wrba, Fritz|Bergmann, Michael|Weinhausel, Andreas|Egger, Gerda
PMID: 26335606
Journal: Biol Res. 2015 Sep 12;48:50.
Title: Colorectal cancer DNA methylation patterns from patients in Manaus, Brazil.
Author: Almeida, Fabiana Greyce Oliveira|de Aquino, Priscila Ferreira|de Souza, Afonso Duarte Leao|de Souza, Antonia Queiroz Lima|do Carmo Vinhote, Sonia|Mac-Cormick, Thais Messias|da Mota Silva, Marcelo Soares|Chalub, Sidney Raimundo Silva|de Saldanha da Gama Fi
PMID: 26363785
Journal: J Coll Physicians Surg Pak. 2015 Sep;25(9):694-5.
Title: Optic Nerve Metastasis from Squamous Cell Carcinoma of the Uterine Cervix.
Author: Tunio, Mutahir A|AlAsiri, Mushabbab|Riaz, Khalid|Abdulmoniem, Reham
PMID: 26374369
Journal: Clin Epigenetics. 2015 Sep 18;7:102.
Title: Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon.
Author: Rajendran, Praveen|Dashwood, Wan-Mohaiza|Li, Li|Kang, Yuki|Kim, Eunah|Johnson, Gavin|Fischer, Kay A|Lohr, Christiane V|Williams, David E|Ho, Emily|Yamamoto, Masayuki|Lieberman, David A|Dashwood, Roderick H
PMID: 26388957
Journal: J Nutrigenet Nutrigenomics. 2015;8(3):114-27.
Title: Phytochemical Indicaxanthin Inhibits Colon Cancer Cell Growth and Affects the DNA Methylation Status by Influencing Epigenetically Modifying Enzyme Expression and Activity.
Author: Naselli, Flores|Belshaw, Nigel Junior|Gentile, Carla|Tutone, Marco|Tesoriere, Luisa|Livrea, Maria Antonietta|Caradonna, Fabio
PMID: 26439130
Journal: Oncotarget. 2015 Nov 10;6(35):38139-50.
Title: miR-124 and miR-506 inhibit colorectal cancer progression by targeting DNMT3B and DNMT1.
Author: Chen, Zhiheng|Liu, Shaojun|Tian, Li|Wu, Minghao|Ai, Feiyan|Tang, Wuliang|Zhao, Lian|Ding, Juan|Zhang, Liyang|Tang, Anliu
PMID: 26497367
Journal: J Exp Clin Cancer Res. 2015 Nov 21;34:142.
Title: A-kinase anchor protein 4 (AKAP4) a promising therapeutic target of colorectal cancer.
Author: Jagadish, Nirmala|Parashar, Deepak|Gupta, Namita|Agarwal, Sumit|Purohit, Sapna|Kumar, Vikash|Sharma, Aditi|Fatima, Rukhsar|Topno, Amos Prashant|Shaha, Chandrima|Suri, Anil
PMID: 26590805
Journal: DNA Cell Biol. 2015 Dec;34(12):743.
Title: Retraction of Relationships Between p16 Gene Promoter Methylation and Clinicopathologic Features of Colorectal Cancer: A Meta-Analysis of 27 Cohort Studies (DOI: 10.1089/dna.2013.2253).
Author:
PMID: 26670712
Journal: Cancer Res Treat. 2016 Jan;48(1):208-15.
Title: p16 Hypermethylation and KRAS Mutation Are Independent Predictors of Cetuximab Plus FOLFIRI Chemotherapy in Patients with Metastatic Colorectal Cancer.
Author: Kim, Se Hyun|Park, Kyu Hyun|Shin, Sang Joon|Lee, Kang Young|Kim, Tae Il|Kim, Nam Kyu|Rha, Sun Young|Roh, Jae Kyung|Ahn, Joong Bae
PMID: 25943321
Journal: Histopathology. 2016 Mar;68(4):578-87.
Title: Serrated tubulovillous adenoma of the large intestine.
Author: Bettington, Mark|Walker, Neal|Rosty, Christophe|Brown, Ian|Clouston, Andrew|McKeone, Diane|Pearson, Sally-Ann|Klein, Kerenaftali|Leggett, Barbara|Whitehall, Vicki
PMID: 26212352
Journal: Acta Biochim Biophys Sin (Shanghai). 2016 Jan;48(1):27-38.
Title: RAS signaling and anti-RAS therapy: lessons learned from genetically engineered mouse models, human cancer cells, and patient-related studies.
Author: Fang, Bingliang
PMID: 26350096
Journal: Int J Cancer. 2016 Mar 1;138(5):1186-98.
Title: A phosphomimetic mutant of RelA/p65 at Ser536 induces apoptosis and senescence: An implication for tumor-suppressive role of Ser536 phosphorylation.
Author: Bu, Yiwen|Li, Xiaoning|He, Yingchun|Huang, Chenfei|Shen, Yi|Cao, Yu|Huang, Dan|Cai, Chuan|Wang, Yuhong|Wang, Ziqi|Liao, Duan-Fang|Cao, Deliang
PMID: 26375985
Journal: Oncogene. 2016 Jun 30;35(26):3365-75.
Title: Radiation promotes colorectal cancer initiation and progression by inducing senescence-associated inflammatory responses.
Author: Kim, S B|Bozeman, R G|Kaisani, A|Kim, W|Zhang, L|Richardson, J A|Wright, W E|Shay, J W
PMID: 26477319
Journal: Mol Cell Biochem. 2016 Jan;412(1-2):141-6.
Title: ANRIL regulates the proliferation of human colorectal cancer cells in both two- and three-dimensional culture.
Author: Naemura, Madoka|Tsunoda, Toshiyuki|Inoue, Yasutoshi|Okamoto, Haruna|Shirasawa, Senji|Kotake, Yojiro
PMID: 26708220
Journal: Mol Carcinog. 2016 Dec;55(12):2077-2088.
Title: Integrated analysis of DNA methylation and mutations in esophageal squamous cell carcinoma.
Author: Kishino, Takayoshi|Niwa, Tohru|Yamashita, Satoshi|Takahashi, Takamasa|Nakazato, Hidetsugu|Nakajima, Takeshi|Igaki, Hiroyasu|Tachimori, Yuji|Suzuki, Yasuyuki|Ushijima, Toshikazu
PMID: 26756304
Journal: J Int Assoc Provid AIDS Care. 2016 May;15(3):194-200.
Title: Squamous Cell Cancer of Unknown Primary and Primary Breast Cancer in an HIV-Infected Woman: The Importance of Cancer Screening for People Living with HIV/AIDS.
Author: Gulvin, Joshua|Aboulafia, David M
PMID: 26864079
Journal: Colorectal Dis. 2016 Jun;18(6):549-61.
Title: Hypermethylated DNA as a biomarker for colorectal cancer: a systematic review.
Author: Rasmussen, S L|Krarup, H B|Sunesen, K G|Pedersen, I S|Madsen, P H|Thorlacius-Ussing, O
PMID: 26998585
Journal: PLoS One. 2016 Mar 21;11(3):e0152050.
Title: Relationships between p14ARF Gene Methylation and Clinicopathological Features of Colorectal Cancer: A Meta-Analysis.
Author: Zhou, Zhangjian|Zhang, Hao|Lai, Jianguo|Diao, Dongmei|Li, Wenhan|Dang, Chengxue|Song, Yongchun
PMID: 26999279
Journal: Mol Carcinog. 2016 Nov;55(11):1796-1806.
Title: Adiponectin induces CXCL1 secretion from cancer cells and promotes tumor angiogenesis by inducing stromal fibroblast senescence.
Author: Cai, Lun|Xu, Shengyuan|Piao, Chunmei|Qiu, Shulan|Li, Huihua|Du, Jie
PMID: 27092462
Journal: Oncol Res. 2016;23(5):237-48.
Title: Raltitrexed Inhibits HepG2 Cell Proliferation via G0/G1 Cell Cycle Arrest.
Author: Zhao, Hongwei|Zhang, Yubao|Sun, Jianmin|Zhan, Chao|Zhao, Liang
PMID: 27098147
Journal: Cancer Epidemiol Biomarkers Prev. 2016 Jul;25(7):1185-91.
Title: Association of Common Susceptibility Variants of Pancreatic Cancer in Higher-Risk Patients: A PACGENE Study.
Author: Childs, Erica J|Chaffee, Kari G|Gallinger, Steven|Syngal, Sapna|Schwartz, Ann G|Cote, Michele L|Bondy, Melissa L|Hruban, Ralph H|Chanock, Stephen J|Hoover, Robert N|Fuchs, Charles S|Rider, David N|Amundadottir, Laufey T|Stolzenberg-Solomon, Rachael|Wolpin
PMID: 27197284
Journal: Genes Chromosomes Cancer. 2016 Nov;55(11):821-33.
Title: Copy number changes of clinically actionable genes in melanoma, non-small cell lung cancer and colorectal cancer-A survey across 822 routine diagnostic cases.
Author: Pfarr, Nicole|Penzel, Roland|Klauschen, Frederick|Heim, Daniel|Brandt, Regine|Kazdal, Daniel|Jesinghaus, Moritz|Herpel, Esther|Schirmacher, Peter|Warth, Arne|Weichert, Wilko|Endris, Volker|Stenzinger, Albrecht
PMID: 27218826
Journal: Virchows Arch. 2016 Aug;469(2):135-44.
Title: Immunohistochemical staining for p16 and BRAFV600E is useful to distinguish between sporadic and hereditary (Lynch syndrome-related) microsatellite instable colorectal carcinomas.
Author: Boissiere-Michot, Florence|Frugier, Helene|Ho-Pun-Cheung, Alexandre|Lopez-Crapez, Evelyne|Duffour, Jacqueline|Bibeau, Frederic
PMID: 27220764
Journal: Mol Med Rep. 2016 Aug;14(2):1714-20.
Title: ANRIL is associated with the survival rate of patients with colorectal cancer, and affects cell migration and invasion in vitro.
Author: Sun, Yi|Zheng, Zhao-Peng|Li, Hang|Zhang, Han-Qun|Ma, Fa-Qiang
PMID: 27314206
Journal: Mol Cancer Res. 2016 Sep;14(9):795-804.
Title: Distinct Transcriptional Changes and Epithelial-Stromal Interactions Are Altered in Early-Stage Colon Cancer Development.
Author: Mo, Allen|Jackson, Stephen|Varma, Kamini|Carpino, Alan|Giardina, Charles|Devers, Thomas J|Rosenberg, Daniel W
PMID: 27353028
Journal: BMC Cancer. 2016 Aug 2;16:571.
Title: CPP2-p16MIS treatment-induced colon carcinoma cell death in vitro and prolonged lifespan of tumor-bearing mice.
Author: Wang, Lifeng|Chen, Haijin|Yu, Jinlong|Lin, Xiaohua|Qi, Jia|Cui, Chunhui|Xie, Lang|Huang, Shuxin
PMID: 27485348
Journal: Cancer Biomark. 2016 Jun 24;17(2):133-43.
Title: KRAS, BRAF oncogene mutations and tissue specific promoter hypermethylation of tumor suppressor SFRP2, DAPK1, MGMT, HIC1 and p16 genes in colorectal cancer patients.
Author: Bagci, Binnur|Sari, Musa|Karadayi, Kursat|Turan, Mustafa|Ozdemir, Ozturk|Bagci, Gokhan
PMID: 27540971
Journal: Med Oncol. 2016 Oct;33(10):106.
Title: Targeted molecular profiling of rare genetic alterations in colorectal cancer using next-generation sequencing.
Author: Jauhri, Mayank|Bhatnagar, Akanksha|Gupta, Satish|Shokeen, Yogender|Minhas, Sachin|Aggarwal, Shyam
PMID: 27568332
Journal: Oncoimmunology. 2015 Sep 2;5(8):e1082704.
Title: Th22 cells control colon tumorigenesis through STAT3 and Polycomb Repression complex 2 signaling.
Author: Sun, Danfeng|Lin, Yanwei|Hong, Jie|Chen, Haoyan|Nagarsheth, Nisha|Peng, Dongjun|Wei, Shuang|Huang, Emina|Fang, Jingyuan|Kryczek, Ilona|Zou, Weiping
PMID: 27622053
Journal: Medicina (Kaunas). 2016;52(5):298-306.
Title: Molecular features of doxorubicin-resistance development in colorectal cancer CX-1 cell line.
Author: Kubiliute, Raimonda|Sulskyte, Indre|Daniunaite, Kristina|Daugelavicius, Rimantas|Jarmalaite, Sonata
PMID: 27746118
Journal: Mol Cancer. 2016 Oct 18;15(1):63.
Title: Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing.
Author: Kovaleva, Valentina|Geissler, Anna-Lena|Lutz, Lisa|Fritsch, Ralph|Makowiec, Frank|Wiesemann, Sebastian|Hopt, Ulrich T|Passlick, Bernward|Werner, Martin|Lassmann, Silke
PMID: 27756406
Journal: Life Sci. 2016 Dec 15;167:67-77.
Title: Arsenic trioxide induces cell cycle arrest and alters DNA methylation patterns of cell cycle regulatory genes in colorectal cancer cells.
Author: Eyvani, Haniyeh|Moghaddaskho, Farima|Kabuli, Majid|Zekri, Ali|Momeny, Majid|Tavakkoly-Bazzaz, Javad|Alimoghaddam, Kamran|Ghavamzadeh, Ardeshir|Ghaffari, Seyed H
PMID: 27769816
Journal: Anticancer Res. 2016 Oct;36(10):5315-5324.
Title: KRAS Mutant Status, p16 and beta-catenin Expression May Predict Local Recurrence in Patients Who Underwent Transanal Endoscopic Microsurgery (TEMS) for Stage I Rectal Cancer.
Author: Sideris, Michail|Moorhead, Jane|Diaz-Cano, Salvador|Bjarnason, Ingvar|Haji, Amyn|Papagrigoriadis, Savvas
PMID: 27798894
Journal: J Proteome Res. 2016 Dec 2;15(12):4412-4422.
Title: Detection of Proteome Changes in Human Colon Cancer Induced by Cell Surface Binding of Growth-Inhibitory Human Galectin-4 Using Quantitative SILAC-Based Proteomics.
Author: Michalak, Malwina|Warnken, Uwe|Andre, Sabine|Schnolzer, Martina|Gabius, Hans-Joachim|Kopitz, Juergen
PMID: 27801591
Journal: Oncotarget. 2016 Dec 13;7(50):83071-83087.
Title: Marine guanidine alkaloids crambescidins inhibit tumor growth and activate intrinsic apoptotic signaling inducing tumor regression in a colorectal carcinoma zebrafish xenograft model.
Author: Roel, Maria|Rubiolo, Juan A|Guerra-Varela, Jorge|Silva, Siguara B L|Thomas, Olivier P|Cabezas-Sainz, Pablo|Sanchez, Laura|Lopez, Rafael|Botana, Luis M
PMID: 27825113
Journal: Saudi J Gastroenterol. 2016 Nov;22(6):435-440.
Title: p16 protein is upregulated in a stepwise fashion in colorectal adenoma and colorectal carcinoma.
Author: Al-Ahwal, Mahmoud|Gomaa, Wafaey|Emam, Eman|Qari, Yousif|Buhmeida, Abdelbaset|Radwi, Salman|Al-Maghrabi, Basim|Al-Qahtani, Mohammad|Al-Maghrabi, Jaudah
PMID: 27976639
Journal: Gut. 2017 Jan;66(1):97-106.
Title: Clinicopathological and molecular features of sessile serrated adenomas with dysplasia or carcinoma.
Author: Bettington, Mark|Walker, Neal|Rosty, Christophe|Brown, Ian|Clouston, Andrew|McKeone, Diane|Pearson, Sally-Ann|Leggett, Barbara|Whitehall, Vicki
PMID: 26475632
Journal: Oncogene. 2017 Mar;36(10):1374-1383.
Title: Disruption of the RP-MDM2-p53 pathway accelerates APC loss-induced colorectal tumorigenesis.
Author: Liu, S|Tackmann, N R|Yang, J|Zhang, Y
PMID: 27617574
Journal: Genes Chromosomes Cancer. 2017 Mar;56(3):199-213.
Title: Novel mouse model recapitulates genome and transcriptome alterations in human colorectal carcinomas.
Author: McNeil, Nicole E|Padilla-Nash, Hesed M|Buishand, Floryne O|Hue, Yue|Ried, Thomas
PMID: 27750367
Journal: Oncotarget. 2017 Jan 3;8(1):364-378.
Title: Epithelial derived-matrix metalloproteinase (MMP9) exhibits a novel defensive role of tumor suppressor in colitis associated cancer by activating MMP9-Notch1-ARF-p53 axis.
Author: Walter, Lewins|Pujada, Adani|Bhatnagar, Noopur|Bialkowska, Agnieszka B|Yang, Vincent W|Laroui, Hamed|Garg, Pallavi
PMID: 27861153
Journal: J Comput Biol. 2017 Jun;24(6):603-615.
Title: pathTiMEx: Joint Inference of Mutually Exclusive Cancer Pathways and Their Progression Dynamics.
Author: Cristea, Simona|Kuipers, Jack|Beerenwinkel, Niko
PMID: 27936934
Journal: JAMA Oncol. 2017 Apr 1;3(4):464-471.
Title: Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer.
Author: Pearlman, Rachel|Frankel, Wendy L|Swanson, Benjamin|Zhao, Weiqiang|Yilmaz, Ahmet|Miller, Kristin|Bacher, Jason|Bigley, Christopher|Nelsen, Lori|Goodfellow, Paul J|Goldberg, Richard M|Paskett, Electra|Shields, Peter G|Freudenheim, Jo L|Stanich, Peter P|Lat
PMID: 27978560
Journal: J Clin Oncol. 2017 Apr 1;35(10):1086-1095.
Title: Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer.
Author: Yurgelun, Matthew B|Kulke, Matthew H|Fuchs, Charles S|Allen, Brian A|Uno, Hajime|Hornick, Jason L|Ukaegbu, Chinedu I|Brais, Lauren K|McNamara, Philip G|Mayer, Robert J|Schrag, Deborah|Meyerhardt, Jeffrey A|Ng, Kimmie|Kidd, John|Singh, Nanda|Hartman, Anne-
PMID: 28135145
Journal: Anticancer Res. 2017 Mar;37(3):1349-1357.
Title: KRAS Mutant Status May Be Associated with Distant Recurrence in Early-stage Rectal Cancer.
Author: Sideris, Michail|Moorhead, Jane|Diaz-Cano, Salvador|Haji, Amyn|Papagrigoriadis, Savvas
PMID: 28314302
Journal: World J Gastrointest Oncol. 2017 Mar 15;9(3):105-120.
Title: CpG island methylator phenotype in adenocarcinomas from the digestive tract: Methods, conclusions, and controversies.
Author: Sanchez-Vega, Francisco|Gotea, Valer|Chen, Yun-Ching|Elnitski, Laura
PMID: 28344746
Journal: Oncotarget. 2017 Mar 14;8(11):18322-18336.
Title: The suppressing effects of BTG3 expression on aggressive behaviors and phenotypes of colorectal cancer: An in vitro and vivo study.
Author: Zheng, Hua-Chuan|He, Hao-Yu|Wu, Ji-Cheng|Li, Jing|Zhao, Shuang|Zhao, Gui-Feng|Jiang, Hua-Mao|Yu, Xue-Wen|Li, Zhi-Jie
PMID: 28407690
Journal: J Biomed Phys Eng. 2017 Mar 1;7(1):79-86. eCollection 2017 Mar.
Title: Effect of Exposure to 900 MHz GSM Mobile Phone Radiofrequency Radiation on Estrogen Receptor Methylation Status in Colon Cells of Male Sprague Dawley Rats.
Author: Mokarram, P|Sheikhi, M|Mortazavi, S M J|Saeb, S|Shokrpour, N
PMID: 28451581
Journal: J Med Chem. 2017 Jun 8;60(11):4665-4679.
Title: Rational Design of Bisubstrate-Type Analogues as Inhibitors of DNA Methyltransferases in Cancer Cells.
Author: Halby, Ludovic|Menon, Yoann|Rilova, Elodie|Pechalrieu, Dany|Masson, Veronique|Faux, Celine|Bouhlel, Mohamed Amine|David-Cordonnier, Marie-Helene|Novosad, Natacha|Aussagues, Yannick|Samson, Arnaud|Lacroix, Laurent|Ausseil, Frederic|Fleury, Laurence|Guianva
PMID: 28463515
Journal: Diagn Pathol. 2017 May 12;12(1):39.
Title: Intestinal differentiated mucinous adenocarcinoma of the endometrium with sporadic MSI high status: a case report.
Author: Trippel, Mafalda|Imboden, Sara|Papadia, Andrea|Mueller, Michael D|Mertineit, Nando|Harma, Kirsi|Nicolae, Alina|Vassella, Erik|Rau, Tilman T
PMID: 28494767
Journal: Gastrointest Endosc. 2017 Dec;86(6):1131-1138.e4.
Title: Endoscopic and molecular characterization of colorectal sessile serrated adenoma/polyps with cytologic dysplasia.
Author: Tanaka, Yoshihito|Yamano, Hiro-O|Yamamoto, Eiichiro|Matushita, Hiro-O|Aoki, Hironori|Yoshikawa, Kenjiro|Takagi, Ryo|Harada, Eiji|Nakaoka, Michiko|Yoshida, Yuko|Eizuka, Makoto|Sugai, Tamotsu|Suzuki, Hiromu|Nakase, Hiroshi
PMID: 28501592
Journal: Clin Epigenetics. 2017 May 18;9:55.
Title: Analysis of the DNA methylation level of cancer-related genes in colorectal cancer and the surrounding normal mucosa.
Author: Sugai, Tamotsu|Yoshida, Masakazu|Eizuka, Makoto|Uesugii, Noriyuki|Habano, Wataru|Otsuka, Kouki|Sasaki, Akira|Yamamoto, Eiichiro|Matsumoto, Takayuki|Suzuki, Hiromu
PMID: 28533824
Journal: Oncol Rep. 2017 Jul;38(1):31-42.
Title: Synthetic lethal interaction of CDK inhibition and autophagy inhibition in human solid cancer cell lines.
Author: Okada, Yoshinari|Kato, Shunsuke|Sakamoto, Yasuhiro|Oishi, Takayuki|Ishioka, Chikashi
PMID: 28560460
Journal: Cancer Lett. 2017 Aug 28;402:110-116.
Title: Epigenetic effects of inhibition of heat shock protein 90 (HSP90) in human pancreatic and colon cancer.
Author: Nagaraju, Ganji Purnachandra|Wu, Christina|Merchant, Neha|Chen, Zhengjia|Lesinski, Gregory B|El-Rayes, Bassel F
PMID: 28583846
Journal: Virchows Arch. 2017 Sep;471(3):329-336.
Title: Intratumoral Fusobacterium nucleatum abundance correlates with macrophage infiltration and CDKN2A methylation in microsatellite-unstable colorectal carcinoma.
Author: Park, Hye Eun|Kim, Jung Ho|Cho, Nam-Yun|Lee, Hye Seung|Kang, Gyeong Hoon
PMID: 28597080
Journal: JAMA Oncol. 2017 Nov 1;3(11):1546-1553.
Title: Genomic Profiling of Small-Bowel Adenocarcinoma.
Author: Schrock, Alexa B|Devoe, Craig E|McWilliams, Robert|Sun, James|Aparicio, Thomas|Stephens, Philip J|Ross, Jeffrey S|Wilson, Richard|Miller, Vincent A|Ali, Siraj M|Overman, Michael J
PMID: 28617917
Journal: Epigenomics. 2017 Jul;9(7):1029-1042.
Title: DNA methylation patterns in ulcerative colitis-associated cancer: a systematic review.
Author: Emmett, Ruth A|Davidson, Katherine L|Gould, Nicholas J|Arasaradnam, Ramesh P
PMID: 28621161
Journal: Adv Med Biol. 2017 1st Quarter;118:83-122.
Title: Haploinsufficient tumor suppressor genes.
Author: Inoue, Kazushi|Fry, Elizabeth A
PMID: 28680740
Journal: Med Oncol. 2017 Aug;34(8):147.
Title: Clinical and prognosis value of the CIMP status combined with MLH1 or p16 (INK4a) methylation in colorectal cancer.
Author: Saadallah-Kallel, Amana|Abdelmaksoud-Dammak, Rania|Triki, Mouna|Charfi, Slim|Khabir, Abdelmajid|Sallemi-Boudawara, Tahia|Mokdad-Gargouri, Raja
PMID: 28730335
Journal: Surg Case Rep. 2017 Aug 30;3(1):96.
Title: Primary colonic well-differentiated / dedifferentiated liposarcoma of the ascending colon: a case report.
Author: Sawayama, Hiroshi|Yoshida, Naoya|Miyamoto, Yuji|Uchihara, Tomoyuki|Toihata, Tasuku|Yagi, Taisuke|Hiyoshi, Yukiharu|Iwatsuki, Masaaki|Baba, Yoshifumi|Baba, Hideo
PMID: 28856628
Journal: J Surg Case Rep. 2017 Sep 21;2017(9):rjx175.
Title: Coincidence or not? A rare case of rectal leiomyosarcoma amidst incidental findings of anal squamous cell carcinoma: case presentation and literature review.
Author: Iwasiuk, Gosta|Nealy, Jason
PMID: 28959428
Journal: Oncotarget. 2017 Jun 27;8(37):61917-61926.
Title: Potential link between Fusobacterium enrichment and DNA methylation accumulation in the inflammatory colonic mucosa in ulcerative colitis.
Author: Tahara, Tomomitsu|Hirata, Ichiro|Nakano, Naoko|Tahara, Sayumi|Horiguchi, Noriyuki|Kawamura, Tomohiko|Okubo, Masaaki|Ishizuka, Takamitsu|Yamada, Hyuga|Yoshida, Dai|Ohmori, Takafumi|Maeda, Kohei|Komura, Naruomi|Ikuno, Hirokazu|Jodai, Yasutaka|Kamano, Toshia
PMID: 28977914
Journal: PLoS One. 2017 Oct 12;12(10):e0185035.
Title: In vitro effects of Apixaban on 5 different cancer cell lines.
Author: Guasti, Luigina|Squizzato, Alessandro|Moretto, Paola|Vigetti, Davide|Ageno, Walter|Dentali, Francesco|Maresca, Andrea M|Campiotti, Leonardo|Grandi, Anna M|Passi, Alberto
PMID: 29023465
Journal: Oncol Rep. 2017 Nov;38(5):2803-2813.
Title: The ethanol extracts of sporoderm-broken spores of Ganoderma lucidum inhibit colorectal cancer in vitro and in vivo.
Author: Li, Kang|Na, Kun|Sang, Tingting|Wu, Kaikai|Wang, Ying|Wang, Xingya
PMID: 29048673
Journal: Asian Pac J Cancer Prev. 2017 Nov 26;18(11):3049-3054.
Title: P16ink4a Subcellular Expression Patterns in Colorectal Adenocarcinoma, Adenoma and Non-Neoplastic Tissue Samples
Author: Charkhat Gorgich, Enam Alhagh|Heidari, Zahra|Mahmoudzadeh- Sagheb, Hamidreza
PMID: 29172278
Journal: Oncotarget. 2017 Dec 4;8(67):111597-111607.
Title: LRP6 targeting suppresses gastric tumorigenesis via P14(ARF)-Mdm2-P53-dependent cellular senescence.
Author: Wang, Haibin|Xu, Guoxing|Huang, Zhengjie|Li, Weizheng|Cai, Huali|Zhang, Yunda|Xiong, Disheng|Liu, Gang|Wang, Shengjie|Xue, Zengfu|Luo, Qi
PMID: 29340077
Journal: Gastroenterol Hepatol Bed Bench. 2017 Fall;10(4):295-302.
Title: Network analysis of common genes related to esophageal, gastric, and colon cancers.
Author: Vaseghi Maghvan, Padina|Rezaei-Tavirani, Mostafa|Zali, Hakimeh|Nikzamir, Abdolrahim|Abdi, Saeed|Khodadoostan, Mahsa|Asadzadeh-Aghdaei, Hamid
PMID: 29379595
Journal: ANZ J Surg. 2018 Mar;88(3):E108-E113.
Title: Metabolic response evaluation for colorectal liver metastases and correlation to pathologic response and tumour markers.
Author: Lau, Lawrence F|Murone, Carmel|Williams, David S|Standish, Richard|Lee, Sze Ting|Christophi, Christopher|Scott, Andrew M|Muralidharan, Vijayaragavan
PMID: 27452367
Journal: J Ethnopharmacol. 2018 Jan 10;210:1-9.
Title: Curcumol induces cell cycle arrest in colon cancer cells via reactive oxygen species and Akt/ GSK3beta/cyclin D1 pathway.
Author: Wang, Juan|Li, Xu-Mei|Bai, Zhun|Chi, Bi-Xia|Wei, Yan|Chen, Xu
PMID: 28684297
Journal: Oncol Res. 2018 Jun 11;26(5):795-800.
Title: miR-133a-3p Targets SUMO-Specific Protease 1 to Inhibit Cell Proliferation and Cell Cycle Progress in Colorectal Cancer.
Author: Zhou, Guo-Qiang|Han, Fu|Shi, Zhi-Liang|Yu, Liang|Li, Xue-Feng|Yu, Cheng|Shen, Cheng-Long|Wan, Dai-Wei|Zhu, Xin-Guo|Li, Rui|He, Song-Bing
PMID: 28748780
Journal: Mol Cell Biochem. 2018 Sep;446(1-2):137-148.
Title: P16 promotes the growth and mobility potential of breast cancer both in vitro and in vivo: the key role of the activation of IL-6/JAK2/STAT3 signaling.
Author: Wang, Le|Zhan, Xiangwen|Shen, Xiaomeng|Li, Mingzhe|Yang, Jianming|Yu, Wenhua|Chen, Hao|Jin, Bo|Mao, Zebin
PMID: 29388151
Journal: Cell Death Dis. 2018 Feb 13;9(2):217.
Title: Baicalin induces cellular senescence in human colon cancer cells via upregulation of DEPP and the activation of Ras/Raf/MEK/ERK signaling.
Author: Wang, Zhou|Ma, Lingman|Su, Mengqi|Zhou, Yiran|Mao, Ke|Li, Chengqin|Peng, Guangyong|Zhou, Changlin|Shen, Baiyong|Dou, Jie
PMID: 29440765
Journal: Chin J Cancer Res. 2018 Feb;30(1):93-103.
Title: Coordinated transcription of ANRIL and P16 genes is silenced by P16 DNA methylation.
Author: Gan, Ying|Ma, Wanru|Wang, Xiuhong|Qiao, Juanli|Zhang, Baozhen|Cui, Chenghua|Liu, Zhaojun|Deng, Dajun
PMID: 29545723
Journal: Exp Ther Med. 2018 Apr;15(4):3173-3180.
Title: DNA methylation is a common molecular alteration in colorectal cancer cells and culture method has no influence on DNA methylation.
Author: Wang, Shibao|Huang, Yinghui|Mu, Xupeng|Qi, Tianyang|Qiao, Sha|Lu, Zhenxia|Li, Hongjun
PMID: 29545832
Journal: Medicine (Baltimore). 2018 Mar;97(12):e0195.
Title: Prognostic and clinicopathological value of p16 protein aberrant expression in colorectal cancer: A PRISMA-compliant Meta-analysis.
Author: Zhou, Ning|Gu, Quankai
PMID: 29561443
Journal: Biomed Pharmacother. 2018 Feb;98:775-782.
Title: Hsa_circ_0014717 is downregulated in colorectal cancer and inhibits tumor growth by promoting p16 expression.
Author: Wang, Feng|Wang, Jun|Cao, Xiangyu|Xu, Lihui|Chen, Lin
PMID: 29571246
Journal: Pharmacogenomics. 2018 Apr;19(5):463-474.
Title: The 9p21 locus as a potential therapeutic target and prognostic marker in colorectal cancer.
Author: Bahrami, Afsane|Hassanian, Seyed Mahdi|Khazaei, Majid|Gharib, Masoumeh|Rahmani, Mahsa|Fiuji, Hamid|Jazayeri, Mir Hadi|Moetamani-Ahmadi, Mehrdad|Ferns, Gordon A|Avan, Amir
PMID: 29629612
Journal: J Proteome Res. 2018 Jun 1;17(6):2216-2225.
Title: Multiproteomic and Transcriptomic Analysis of Oncogenic beta-Catenin Molecular Networks.
Author: Ewing, Rob M|Song, Jing|Gokulrangan, Giridharan|Bai, Sheldon|Bowler, Emily H|Bolton, Rachel|Skipp, Paul|Wang, Yihua|Wang, Zhenghe
PMID: 29747501
Journal: Gynecol Oncol. 2018 Jul;150(1):127-135.
Title: Massively parallel sequencing analysis of mucinous ovarian carcinomas: genomic profiling and differential diagnoses.
Author: Mueller, Jennifer J|Schlappe, Brooke A|Kumar, Rahul|Olvera, Narciso|Dao, Fanny|Abu-Rustum, Nadeem|Aghajanian, Carol|DeLair, Deborah|Hussein, Yaser R|Soslow, Robert A|Levine, Douglas A|Weigelt, Britta
PMID: 29793804
Journal: Yonsei Med J. 2018 Jul;59(5):588-594.
Title: CpG Island Methylator Phenotype and Methylation of Wnt Pathway Genes Together Predict Survival in Patients with Colorectal Cancer.
Author: Kim, Se Hyun|Park, Kyu Hyun|Shin, Sang Joon|Lee, Kang Young|Kim, Tae Il|Kim, Nam Kyu|Rha, Sun Young|Ahn, Joong Bae
PMID: 29869456
Journal: Eur Rev Med Pharmacol Sci. 2018 Jun;22(12):3755-3762.
Title: Evaluation of magnetic resonance imaging in staging of rectal cancer and its relationship with P16 expression.
Author: Zheng, N|Li, Y-Y|Cao, Y-C|Liu, S|Wang, C-H|Liu, W-J
PMID: 29949150
Journal: Br J Nutr. 2018 Aug 30:1-10.
Title: Hypomethylation of NANOG promoter in colonic mucosal cells of obese patients: a possible role of NF-kappaB.
Author: Sedaghat, Fatemeh|Cheraghpour, Makan|Hosseini, Seyed Ahmad|Pourvali, Katayoun|Toolabi, Ladan Teimoori|Mehrtash, Amirhosein|Talaei, Ramin|Zand, Hamid
PMID: 30157990
Journal: Oncol Lett. 2018 Oct;16(4):5275-5281.
Title: Increased EZH2 expression during the adenoma-carcinoma sequence in colorectal cancer.
Author: Ohuchi, Mayuko|Sakamoto, Yasuo|Tokunaga, Ryuma|Kiyozumi, Yuki|Nakamura, Kenichi|Izumi, Daisuke|Kosumi, Keisuke|Harada, Kazuto|Kurashige, Junji|Iwatsuki, Masaaki|Baba, Yoshifumi|Miyamoto, Yuji|Yoshida, Naoya|Shono, Takashi|Naoe, Hideaki|Sasaki, Yutaka|Baba
PMID: 30214616
Journal: Sci Adv. 2018 Sep 28;4(9):eaat6459.
Title: Facile profiling of molecular heterogeneity by microfluidic digital melt.
Author: O'Keefe, Christine M|Pisanic, Thomas R 2nd|Zec, Helena|Overman, Michael J|Herman, James G|Wang, Tza-Huei
PMID: 30263958
Journal: BMC Cancer. 2018 Oct 22;18(1):1023.
Title: The hypermethylation of p16 gene exon 1 and exon 2: potential biomarkers for colorectal cancer and are associated with cancer pathological staging.
Author: Ye, Xiaoxia|Mo, Mingming|Xu, Simin|Yang, Qingjin|Wu, Minhua|Zhang, Junjie|Chen, Bin|Li, Jian|Zhong, Yu|Huang, Qionglin|Cai, Chun
PMID: 30348132
Journal: Eur J Cancer Prev. 2018 Oct 30.
Title: Impact of catechol-O-methyltransferase gene variants on methylation status of P16 and MGMT genes and their downregulation in colorectal cancer.
Author: Wani, Hilal A|Majid, Sabhiya|Bhat, Arif A|Amin, Shajrul|Farooq, Rabia|Bhat, Showkat A|Naikoo, Nissar A|Beigh, Mushtaq A|Kadla, Showkat A
PMID: 30379684