Primary Site >> Colorectal Cancer

Gene >> CDKN1B

Journal: Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6380-5.
Title: High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers.
Author: Fredersdorf, S|Burns, J|Milne, A M|Packham, G|Fallis, L|Gillett, C E|Royds, J A|Peston, D|Hall, P A|Hanby, A M|Barnes, D M|Shousha, S|O'Hare, M J|Lu, X
PMID: 9177226
Journal: Jpn J Cancer Res. 1997 Jul;88(7):625-9.
Title: Reduced expression of cyclin-dependent kinase inhibitor p27Kip1 is associated with advanced stage and invasiveness of gastric carcinomas.
Author: Yasui, W|Kudo, Y|Semba, S|Yokozaki, H|Tahara, E
PMID: 9310133
Journal: Cancer Res. 1997 Nov 1;57(21):4838-48.
Title: Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase.
Author: Moyer, J D|Barbacci, E G|Iwata, K K|Arnold, L|Boman, B|Cunningham, A|DiOrio, C|Doty, J|Morin, M J|Moyer, M P|Neveu, M|Pollack, V A|Pustilnik, L R|Reynolds, M M|Sloan, D|Theleman, A|Miller, P
PMID: 9354447
Journal: Clin Cancer Res. 1997 Dec;3(12 Pt 2):2696-702.
Title: Disorders in cell circuitry associated with multistage carcinogenesis: exploitable targets for cancer prevention and therapy.
Author: Weinstein, I B|Begemann, M|Zhou, P|Han, E K|Sgambato, A|Doki, Y|Arber, N|Ciaparrone, M|Yamamoto, H
PMID: 10068276
Journal: Cancer Res. 1998 Jan 1;58(1):114-22.
Title: Localization and expression of p27KIP1 in multistage colorectal carcinogenesis.
Author: Ciaparrone, M|Yamamoto, H|Yao, Y|Sgambato, A|Cattoretti, G|Tomita, N|Monden, T|Rotterdam, H|Weinstein, I B
PMID: 9426067
Journal: Int J Oncol. 1998 Sep;13(3):611-7.
Title: gamma-Linolenic acid blocks cell cycle progression by regulating phosphorylation of p27kip1 and p57kip2 and their interactions with other cycle regulators in cancer cells.
Author: Jiang, W G|Bryce, R P|Horrobin, D F|Mansel, R E
PMID: 9683802
Journal: Int J Cancer. 1998 Aug 31;77(5):796-802.
Title: Contribution of the cyclin-dependent kinase inhibitor p27KIP1 to the confluence-dependent resistance of HT29 human colon carcinoma cells.
Author: Dimanche-Boitrel, M T|Micheau, O|Hammann, A|Haugg, M|Eymin, B|Chauffert, B|Solary, E
PMID: 9688315
Journal: Cancer. 1998 Dec 15;83(12):2447-55.
Title: Reduced expression of cyclin-dependent kinase inhibitor p27Kip1 is an indicator of malignant behavior in oral squamous cell carcinoma.
Author: Kudo, Y|Takata, T|Yasui, W|Ogawa, I|Miyauchi, M|Takekoshi, T|Tahara, E|Nikai, H
PMID: 9874448
Journal: Oncogene. 1999 Jan 7;18(1):103-15.
Title: Comparative effects of overexpression of p27Kip1 and p21Cip1/Waf1 on growth and differentiation in human colon carcinoma cells.
Author: Yamamoto, H|Soh, J W|Shirin, H|Xing, W Q|Lim, J T|Yao, Y|Slosberg, E|Tomita, N|Schieren, I|Weinstein, I B
PMID: 9926925
Journal: Ann Surg Oncol. 1999 Jan-Feb;6(1):19-25.
Title: Absence of the cell cycle inhibitor p27Kip1 protein predicts poor outcome in patients with stage I-III colorectal cancer.
Author: Belluco, C|Esposito, G|Bertorelle, R|Del Mistro, A|Fassina, A|Vieceli, G|Chieco-Bianchi, L|Nitti, D|Lise, M
PMID: 10030411
Journal: Mol Cell Biol. 1999 May;19(5):3916-28.
Title: Induction of p21(WAF1/CIP1) and inhibition of Cdk2 mediated by the tumor suppressor p16(INK4a).
Author: Mitra, J|Dai, C Y|Somasundaram, K|El-Deiry, W S|Satyamoorthy, K|Herlyn, M|Enders, G H
PMID: 10207115
Journal: Clin Cancer Res. 1999 May;5(5):1057-62.
Title: Paradoxical correlations of cyclin-dependent kinase inhibitors p21waf1/cip1 and p27kip1 in metastatic colorectal carcinoma.
Author: Cheng, J D|Werness, B A|Babb, J S|Meropol, N J
PMID: 10353738
Journal: Cancer Res. 1999 Jul 1;59(13):3245-50.
Title: Loss of P27Kip1 expression correlates with tumor grade and with reduced disease-free survival in primary superficial bladder cancers.
Author: Sgambato, A|Migaldi, M|Faraglia, B|Garagnani, L|Romano, G|De Gaetani, C|Ferrari, P|Capelli, G|Trentini, G P|Cittadini, A
PMID: 10397272
Journal: J Pathol. 1999 May;188(1):18-23.
Title: Prognostic significance of p27(Kip1) expression in colorectal cancer: a clinico-pathological characterization.
Author: Palmqvist, R|Stenling, R|Oberg, A|Landberg, G
PMID: 10398135
Journal: Mod Pathol. 1999 Aug;12(8):751-5.
Title: Levels of expression of p27KIP1 protein in human prostate and prostate cancer: an immunohistochemical analysis.
Author: Erdamar, S|Yang, G|Harper, J W|Lu, X|Kattan, M W|Thompson, T C|Wheeler, T M
PMID: 10463475
Journal: Mol Carcinog. 1999 Nov;26(3):172-9.
Title: Reduced expression and altered subcellular localization of the cyclin-dependent kinase inhibitor p27(Kip1) in human colon cancer.
Author: Sgambato, A|Ratto, C|Faraglia, B|Merico, M|Ardito, R|Schinzari, G|Romano, G|Cittadini, A R
PMID: 10559792
Journal: Crit Rev Oncog. 1999;10(4):303-60.
Title: The role for transforming growth factor-beta (TGF-beta) in human cancer.
Author: Gold, L I
PMID: 10654929
Journal: Jpn J Cancer Res. 1999 Dec;90(12):1364-72.
Title: G1-checkpoint function including a cyclin-dependent kinase 2 regulatory pathway as potential determinant of 7-hydroxystaurosporine (UCN-01)-induced apoptosis and G1-phase accumulation.
Author: Akiyama, T|Sugiyama, K|Shimizu, M|Tamaoki, T|Akinaga, S
PMID: 10665655
Journal: Pathobiology. 1999 Jul-Aug;67(4):174-9.
Title: Expression of cell-cycle-regulating transcription factor E2F-1 in colorectal carcinomas.
Author: Yasui, W|Fujimoto, J|Suzuki, T|Ono, S|Naka, K|Yokozaki, H|Tahara, E
PMID: 10738178
Journal: Colorectal Dis. 1999 Nov;1(6):315-23.
Title: p27(kipl) protein expression: an independent prognostic factor in rectal carcinoma stages I-III.
Author: Pucciarelli|Esposito|Fassina|Alaggio|Masin|Toppan|Chieco-Bianchi|Lise
PMID: 23574593
Journal: Carcinogenesis. 2000 May;21(5):857-64.
Title: Disorders in cell circuitry during multistage carcinogenesis: the role of homeostasis.
Author: Weinstein, I B
PMID: 10783304
Journal: Anticancer Res. 2000 Mar-Apr;20(2A):779-84.
Title: Induction of apoptosis in human gastric cancer by sodium butyrate.
Author: Litvak, D A|Hwang, K O|Evers, B M|Townsend, C M Jr
PMID: 10810354
Journal: Anticancer Res. 2000 Mar-Apr;20(2A):849-52.
Title: P27KiP1 overexpression inhibits the growth and doxorubicin sensitivity of HT29 human colon cancer cells in vivo.
Author: Dimanche-Boitrel, M T|Micheau, O|France, D|Hammann, A|Duchamp, O|Genne, P|Solary, E
PMID: 10810365
Journal: J Surg Res. 2000 Jul;92(1):78-84.
Title: p27(kip1) expression in rectal cancer correlates with disease-free survival.
Author: Gunther, K|Jung, A|Volker, U|Meyer, M|Brabletz, T|Matzel, K E|Reymond, M A|Kirchner, T|Hohenberger, W
PMID: 10864486
Journal: Clin Cancer Res. 2000 Jul;6(7):2881-90.
Title: Augmentation of antitumor activity of 5-fluorouracil by interferon alpha is associated with up-regulation of p27Kip1 in human hepatocellular carcinoma cells.
Author: Eguchi, H|Nagano, H|Yamamoto, H|Miyamoto, A|Kondo, M|Dono, K|Nakamori, S|Umeshita, K|Sakon, M|Monden, M
PMID: 10914738
Journal: Clin Cancer Res. 2000 Jul;6(7):2951-8.
Title: Changes in E2F binding after phenylbutyrate-induced differentiation of Caco-2 colon cancer cells.
Author: Wang, Q M|Feinman, R|Kashanchi, F|Houghton, J M|Studzinski, G P|Harrison, L E
PMID: 10914745
Journal: Urology. 2000 Oct 1;56(4):689-95.
Title: Cyclin-dependent kinase inhibitor P27(KIP1) is expressed preferentially in early stages of urothelial carcinoma.
Author: Franke, K H|Miklosi, M|Goebell, P|Clasen, S|Steinhoff, C|Anastasiadis, A G|Gerharz, C|Schulz, W A
PMID: 11018640
Journal: Int J Biochem Cell Biol. 2000 Sep;32(9):957-65.
Title: Lovastatin and simvastatin are modulators of the proteasome.
Author: Wojcik, C|Bury, M|Stoklosa, T|Giermasz, A|Feleszko, W|Mlynarczuk, I|Pleban, E|Basak, G|Omura, S|Jakobisiak, M
PMID: 11084375
Journal: Endocrinology. 2000 Nov;141(11):3931-9.
Title: A vitamin D3 analog induces a G1-phase arrest in CaCo-2 cells by inhibiting cdk2 and cdk6: roles of cyclin E, p21Waf1, and p27Kip1.
Author: Scaglione-Sewell, B A|Bissonnette, M|Skarosi, S|Abraham, C|Brasitus, T A
PMID: 11089522
Journal: Biomarkers. 2000;5(3):225-34.
Title: Expression of p27(Kip1) and bcl-2, cigarette smoking, and colorectal cancer risk.
Author: Ishibe, N|Freedman, A N|Michalek, A M|Iacobuziodonahue, C|Mettlin, C J|Petrelli, N J|Asirwatham, J E|Hamilton, S R
PMID: 23889224
Journal: Oncogene. 2001 Apr 5;20(15):1913-22.
Title: Fibroblast growth factor and insulin-like growth factor differentially modulate the apoptosis and G1 arrest induced by anti-epidermal growth factor receptor monoclonal antibody.
Author: Liu, B|Fang, M|Lu, Y|Mendelsohn, J|Fan, Z
PMID: 11313939
Journal: Biochem Biophys Res Commun. 2001 Apr 27;283(1):80-5.
Title: 1,25-Dihydroxycholecalciferol enhances butyrate-induced p21(Waf1/Cip1) expression.
Author: Gaschott, T|Wachtershauser, A|Steinhilber, D|Stein, J
PMID: 11322770
Journal: Cancer. 2001 May 1;91(9):1745-51.
Title: Inverse relation between levels of p27(Kip1) and of its ubiquitin ligase subunit Skp2 in colorectal carcinomas.
Author: Hershko, D|Bornstein, G|Ben-Izhak, O|Carrano, A|Pagano, M|Krausz, M M|Hershko, A
PMID: 11335900
Journal: Endocr Relat Cancer. 2001 Mar;8(1):3-9.
Title: The epidermal growth factor receptor as a target for cancer therapy.
Author: Mendelsohn, J
PMID: 11350723
Journal: Ann Surg Oncol. 2001 May;8(4):311-8.
Title: P27kip1 expression is associated with tumor response to preoperative chemoradiotherapy in rectal cancer.
Author: Esposito, G|Pucciarelli, S|Alaggio, R|Giacomelli, L|Marchiori, E|Iaderosa, G A|Friso, M L|Toppan, P|Chieco-Bianchi, L|Lise, M
PMID: 11352304
Journal: J Cell Biol. 2001 Aug 6;154(3):573-84.
Title: Expression of alpha-catenin in alpha-catenin-deficient cells increases resistance to sphingosine-induced apoptosis.
Author: Matsubara, S|Ozawa, M
PMID: 11489917
Journal: FASEB J. 2001 Dec;15(14):2742-4. Epub 2001 Oct 15.
Title: COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib.
Author: Grosch, S|Tegeder, I|Niederberger, E|Brautigam, L|Geisslinger, G
PMID: 11606477
Journal: Oncol Rep. 2002 Jan-Feb;9(1):29-33.
Title: 5-FU improves p27-related poor prognosis in patients with Astler-Coller B2-C colorectal carcinoma.
Author: Kobayashi, Minako|Shiraishi, Taizo|Tonouchi, Hitoshi|Miki, Chikao|Kusunoki, Masato
PMID: 11748451
Journal: Biochem Biophys Res Commun. 2002 Jan 11;290(1):504-9.
Title: ZK 156718, a low calcemic, antiproliferative, and prodifferentiating vitamin D analog.
Author: Gaschott, Tanja|Steinmeyer, Andreas|Steinhilber, Dieter|Stein, Jurgen
PMID: 11779200
Journal: J Nutr. 2002 Feb;132(2):298-302.
Title: Piceatannol, a natural analog of resveratrol, inhibits progression through the S phase of the cell cycle in colorectal cancer cell lines.
Author: Wolter, Freya|Clausnitzer, Antje|Akoglu, Bora|Stein, Jurgen
PMID: 11823594
Journal: Mol Cell Biol. 2002 Apr;22(7):2025-36.
Title: Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors.
Author: Kops, Geert J P L|Medema, Rene H|Glassford, Janet|Essers, Marieke A G|Dijkers, Pascale F|Coffer, Paul J|Lam, Eric W-F|Burgering, Boudewijn M T
PMID: 11884591
Journal: Int J Cancer. 2002 Apr 10;98(5):665-73.
Title: Insulin-like growth factor-I has a biphasic effect on colon carcinoma cells through transient inactivation of forkhead1, initially mitogenic, then mediating growth arrest and differentiation.
Author: Ewton, Daina Z|Kansra, Sanjay|Lim, Seunghwan|Friedman, Eileen
PMID: 11920634
Journal: Toxicol Appl Pharmacol. 2002 Apr 1;180(1):22-35.
Title: Antitumor effects of miconazole on human colon carcinoma xenografts in nude mice through induction of apoptosis and G0/G1 cell cycle arrest.
Author: Wu, Chih-Hsiung|Jeng, Jiiang-Huei|Wang, Ying-Jan|Tseng, Chia-Jen|Liang, Yu-Chih|Chen, Chien-Ho|Lee, Horng-Mo|Lin, Jen-Kun|Lin, Chien-Huang|Lin, Shyr-Yi|Li, Chung-Pei|Ho, Yuan-Soon
PMID: 11922774
Journal: Int J Colorectal Dis. 2002 Jan;17(1):11-9.
Title: p21, p27, cyclin D1, and p53 in rectal cancer: immunohistology with prognostic significance?
Author: Schwandner, O|Bruch, H P|Broll, R
PMID: 12018448
Journal: Am J Clin Pathol. 2002 Jun;117(6):908-15.
Title: High apoptotic activity and low epithelial cell proliferation with underexpression of p21(WAF1/CIP1) and p27Kip1 of mucinous carcinomas of the colorectum: comparison with well-differentiated type.
Author: Akino, Fumiyuki|Mitomi, Hiroyuki|Nakamura, Takatoshi|Ohtani, Yoshimasa|Ichinoe, Masaaki|Okayasu, Isao
PMID: 12047142
Journal: Cancer Cell. 2002 May;1(4):355-68.
Title: Pathway-specific tumor suppression. Reduction of p27 accelerates gastrointestinal tumorigenesis in Apc mutant mice, but not in Smad3 mutant mice.
Author: Philipp-Staheli, Jeannette|Kim, Kyung-Hoon|Payne, Shannon R|Gurley, Kay E|Liggitt, Denny|Longton, Gary|Kemp, Christopher J
PMID: 12086850
Journal: J Nutr. 2002 Jul;132(7):2082-6.
Title: Resveratrol enhances the differentiation induced by butyrate in caco-2 colon cancer cells.
Author: Wolter, Freya|Stein, Jurgen
PMID: 12097697
Journal: Cancer Res. 2002 Jul 15;62(14):3997-4006.
Title: Growth inhibition of human hepatoma cells by acyclic retinoid is associated with induction of p21(CIP1) and inhibition of expression of cyclin D1.
Author: Suzui, Masumi|Masuda, Muneyuki|Lim, Jin T E|Albanese, Chris|Pestell, Richard G|Weinstein, I Bernard
PMID: 12124333
Journal: J Cell Biochem. 2002;87(2):147-59.
Title: Ketoconazole potentiates terfenadine-induced apoptosis in human Hep G2 cells through inhibition of cytochrome p450 3A4 activity.
Author: Wang, Ying-Jan|Yu, Cheng-Fei|Chen, Li-Ching|Chen, Chien-Ho|Lin, Jen-Kun|Liang, Yu-Chih|Lin, Chien-Huang|Lin, Shyr-Yi|Chen, Chin-Fa|Ho, Yuan-Soon
PMID: 12244568
Journal: Hum Pathol. 2002 Oct;33(10):1006-15.
Title: Cyclin A correlates with carcinogenesis and metastasis, and p27(kip1) correlates with lymphatic invasion, in colorectal neoplasms.
Author: Li, Jia-Qing|Miki, Hiroshi|Wu, Fei|Saoo, Kousuke|Nishioka, Mikio|Ohmori, Masaki|Imaida, Katsumi
PMID: 12395374
Journal: Eur Surg Res. 2002 Nov-Dec;34(6):389-96.
Title: Prognostic significance of p21 and p27 protein, apoptosis, clinical and histologic factors in rectal cancer without lymph node metastases.
Author: Schwandner, O|Bruch, H-P|Broll, R
PMID: 12403937
Journal: Int J Cancer. 2003 Jan 1;103(1):21-8.
Title: Rapid turnover of cell-cycle regulators found in Mirk/dyrk1B transfectants.
Author: Ewton, Daina Z|Lee, Kangmoon|Deng, Xiaobing|Lim, Seunghwan|Friedman, Eileen
PMID: 12455049
Journal: Cancer Cell. 2003 Mar;3(3):233-45.
Title: Proliferation of cancer cells despite CDK2 inhibition.
Author: Tetsu, Osamu|McCormick, Frank
PMID: 12676582
Journal: J Gene Med. 2003 Apr;5(4):287-99.
Title: 5-Fluorouracil efficiently enhanced apoptosis induced by adenovirus-mediated transfer of caspase-8 in DLD-1 colon cancer cells.
Author: Uchida, Hiroaki|Shinoura, Nobusada|Kitayama, Joji|Watanabe, Toshiaki|Nagawa, Hirokazu|Hamada, Hirofumi
PMID: 12692863
Journal: Oncol Rep. 2003 Jul-Aug;10(4):827-31.
Title: Prognostic significance of p27/kip1 and apoptosis in patients with colorectal carcinoma.
Author: Noguchi, Tsuyoshi|Kikuchi, Ryuichi|Ono, Kiyoshi|Takeno, Shinsuke|Moriyama, Hatsuo|Uchida, Yuzo
PMID: 12792730
Journal: Int J Cancer. 2003 Aug 10;106(1):125-37.
Title: In vitro and in vivo studies of the anticancer action of terbinafine in human cancer cell lines: G0/G1 p53-associated cell cycle arrest.
Author: Lee, Wen-Sen|Chen, Rong-Jane|Wang, Ying-Jan|Tseng, How|Jeng, Jiiang-Huei|Lin, Shyr-Yi|Liang, Yu-Chih|Chen, Chien-Ho|Lin, Chien-Huang|Lin, Jen-Kun|Ho, Pei-Yin|Chu, Jan-Show|Ho, Wei-Lu|Chen, Li-Ching|Ho, Yuan-Soon
PMID: 12794767
Journal: Clin Cancer Res. 2003 Jul;9(7):2457-64.
Title: A pharmacodynamic study of the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in metastatic colorectal cancer patients.
Author: Daneshmand, Manijeh|Parolin, Doris A E|Hirte, Holger W|Major, Pierre|Goss, Glenwood|Stewart, David|Batist, Gerald|Miller, Wilson H Jr|Matthews, Sarah|Seymour, Lesley|Lorimer, Ian A J
PMID: 12855618
Journal: J Cancer Res Clin Oncol. 2003 Aug;129(8):449-55.
Title: Different apoptotic activity and p21(WAF1/CIP1), but not p27(Kip1), expression in serrated adenomas as compared with traditional adenomas and hyperplastic polyps of the colorectum.
Author: Mitomi, Hiroyuki|Sada, Miwa|Kobayashi, Kiyonori|Igarashi, Masahiro|Mori, Akio|Kanazawa, Hideki|Nishiyama, Yasuhiko|Ihara, Atsushi|Otani, Yoshimasa
PMID: 12884030
Journal: J Surg Res. 2003 Aug;113(2):179-88.
Title: P27 does not predict histopathological response to radiochemotherapy in rectal cancer.
Author: Gunther, Klaus|Dimmler, Arno|Rodel, Franz|Reulbach, Udo|Merkel, Susanne|Bittorf, Birgit R|Matzel, Klaus E|Papadopoulos, Thomas|Hohenberger, Werner|Sauer, Rolf|Rodel, Claus
PMID: 12957127
Journal: J Clin Oncol. 2003 Oct 1;21(19):3594-600.
Title: High p27Kip1 expression predicts superior relapse-free and overall survival for premenopausal women with early-stage breast cancer receiving adjuvant treatment with tamoxifen plus goserelin.
Author: Pohl, Gudrun|Rudas, Margaretha|Dietze, Otto|Lax, Sigurd|Markis, Eva|Pirker, Robert|Zielinski, Christoph C|Hausmaninger, Hubert|Kubista, Ernst|Samonigg, Hellmut|Jakesz, Raimund|Filipits, Martin
PMID: 14512390
Journal: Dig Liver Dis. 2003 Aug;35(8):557-65.
Title: Molecular mechanisms involved in the antiproliferative effect of two COX-2 inhibitors, nimesulide and NS-398, on colorectal cancer cell lines.
Author: Buecher, B|Broquet, A|Bouancheau, D|Heymann, M F|Jany, A|Denis, M G|Bonnet, C|Galmiche, J P|Blottiere, H M
PMID: 14567460
Journal: Oncogene. 2003 Nov 13;22(51):8271-82.
Title: Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells.
Author: Agarwal, Chapla|Singh, Rana P|Dhanalakshmi, Sivanandhan|Tyagi, Anil K|Tecklenburg, Marianne|Sclafani, Robert A|Agarwal, Rajesh
PMID: 14614451
Journal: Nutr Cancer. 2003;46(2):186-96.
Title: Anthocyanin-rich extract from Aronia meloncarpa E induces a cell cycle block in colon cancer but not normal colonic cells.
Author: Malik, Minnie|Zhao, Cuiwei|Schoene, Norberta|Guisti, M Monica|Moyer, Mary P|Magnuson, Bernadene A
PMID: 14690795
Journal: Biochem Pharmacol. 2004 Apr 15;67(8):1469-78.
Title: Cyclooxygenase-2 (COX-2)-dependent and -independent anticarcinogenic effects of celecoxib in human colon carcinoma cells.
Author: Maier, Thorsten Jurgen|Schilling, Karin|Schmidt, Ronald|Geisslinger, Gerd|Grosch, Sabine
PMID: 15041464
Journal: Int J Colorectal Dis. 2004 Jul;19(4):325-33. Epub 2004 Apr 2.
Title: Immunohistochemical expression of cyclin D1, cyclin E, p21/waf1 and p27/kip1 in inflammatory bowel disease: correlation with other cell-cycle-related proteins (Rb, p53, ki-67 and PCNA) and clinicopathological features.
Author: Ioachim, Elli E|Katsanos, Konstantinos H|Michael, Michael C|Tsianos, Epameinondas V|Agnantis, Niki J
PMID: 15060836
Journal: Cancer. 2004 Apr 15;100(8):1615-21.
Title: Alterations in the expression of the cell cycle regulatory protein cyclin kinase subunit 1 in colorectal carcinoma.
Author: Shapira, Ma'anit|Ben-Izhak, Ofer|Bishara, Bishara|Futerman, Boris|Minkov, Ira|Krausz, Michael M|Pagano, Michele|Hershko, Dan D
PMID: 15073847
Journal: Int J Hyperthermia. 2004 Jun;20(4):405-19.
Title: Thermal enhancement of oxaliplatin-induced inhibition of cell proliferation and cell cycle progression in human carcinoma cell lines.
Author: Atallah, D|Marsaud, V|Radanyi, C|Kornprobst, M|Rouzier, R|Elias, D|Renoir, J-M
PMID: 15204521
Journal: Cancer Res. 2004 Sep 1;64(17):6050-7.
Title: Hath1, down-regulated in colon adenocarcinomas, inhibits proliferation and tumorigenesis of colon cancer cells.
Author: Leow, Ching Ching|Romero, Maria S|Ross, Sarajane|Polakis, Paul|Gao, Wei-Qiang
PMID: 15342386
Journal: Biochem Biophys Res Commun. 2004 Nov 12;324(2):878-86.
Title: Cell cycle-related signaling pathways modulated by peripheral benzodiazepine receptor ligands in colorectal cancer cells.
Author: Maaser, Kerstin|Sutter, Andreas P|Krahn, Antje|Hopfner, Michael|Grabowski, Patricia|Scherubl, Hans
PMID: 15474510
Journal: Am J Pathol. 2004 Nov;165(5):1489-98.
Title: Colonic crypt changes during adenoma development in familial adenomatous polyposis: immunohistochemical evidence for expansion of the crypt base cell population.
Author: Boman, Bruce M|Walters, Rhonda|Fields, Jeremy Z|Kovatich, Albert J|Zhang, Tao|Isenberg, Gerald A|Goldstein, Scott D|Palazzo, Juan P
PMID: 15509520
Journal: World J Gastroenterol. 2004 Dec 1;10(23):3441-54.
Title: Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis.
Author: Xu, Xiao-Li|Yu, Jian|Zhang, Hong-Yu|Sun, Meng-Hong|Gu, Jun|Du, Xiang|Shi, Da-Ren|Wang, Peng|Yang, Zhen-Hua|Zhu, Jing-De
PMID: 15526363
Journal: Mol Carcinog. 2005 Feb;42(2):109-20.
Title: Tumorigenesis in p27/p53- and p18/p53-double null mice: functional collaboration between the pRb and p53 pathways.
Author: Damo, Lorna A|Snyder, Paul W|Franklin, David S
PMID: 15584024
Journal: Eur J Med Chem. 2005 Jan;40(1):85-92.
Title: Synthesis and cytotoxic activity of 2-acyl-1H-indole-4,7-diones on human cancer cell lines.
Author: Mahboobi, Siavosh|Sellmer, Andreas|Eichhorn, Emerich|Beckers, Thomas|Fiebig, Heinz-Herbert|Kelter, Gerhard
PMID: 15642413
Journal: Cancer. 2005 Apr 1;103(7):1336-46.
Title: The prognostic impact of the ubiquitin ligase subunits Skp2 and Cks1 in colorectal carcinoma.
Author: Shapira, Ma'anit|Ben-Izhak, Ofer|Linn, Shai|Futerman, Boris|Minkov, Ira|Hershko, Dan D
PMID: 15717322
Journal: Appl Immunohistochem Mol Morphol. 2005 Mar;13(1):38-44.
Title: The clinical significance of p53, p21, and p27 expressions in rectal carcinoma.
Author: Lebe, Banu|Sarioglu, Sulen|Sokmen, Selman|Ellidokuz, Hulya|Fuzun, Mehmet|Kupelioglu, Ali
PMID: 15722792
Journal: Appl Immunohistochem Mol Morphol. 2005 Mar;13(1):45-54.
Title: Prognostic significance of DCC and p27Kip1 in colorectal cancer.
Author: Wu, James T|Kakar, Sanjay|Nelson, Richard L|Mihalov, Michael L|Hayward, Brooke|Gilbert, Peter B|Ghosh, Luna
PMID: 15722793
Journal: Cell Signal. 2005 Jul;17(7):809-16. Epub 2004 Nov 24.
Title: Ciglitazone-induced cellular anti-proliferation increases p27kip1 protein levels through both increased transcriptional activity and inhibition of proteasome degradation.
Author: Chen, Fei|Harrison, Lawrence E
PMID: 15763423
Journal: Am J Pathol. 2005 Apr;166(4):1239-46.
Title: Inactivation of p21WAF1/cip1 enhances intestinal tumor formation in Muc2-/- mice.
Author: Yang, Wancai|Velcich, Anna|Lozonschi, Ioana|Liang, Jiao|Nicholas, Courtney|Zhuang, Min|Bancroft, Laura|Augenlicht, Leonard H
PMID: 15793302
Journal: Cancer Res. 2005 May 15;65(10):4253-60.
Title: HER2 overexpression increases sensitivity to gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, through inhibition of HER2/HER3 heterodimer formation in lung cancer cells.
Author: Hirata, Akira|Hosoi, Fumihito|Miyagawa, Miho|Ueda, Shu-ichi|Naito, Seiji|Fujii, Teruhiko|Kuwano, Michihiko|Ono, Mayumi
PMID: 15899817
Journal: Food Chem Toxicol. 2005 Oct;43(10):1483-95.
Title: Molecular mechanisms of econazole-induced toxicity on human colon cancer cells: G0/G1 cell cycle arrest and caspase 8-independent apoptotic signaling pathways.
Author: Ho, Yuan-Soon|Wu, Chih-Hsiung|Chou, Hsiao-Min|Wang, Ying-Jan|Tseng, How|Chen, Chien-Ho|Chen, Li-Ching|Lee, Chia-Hwa|Lin, Shyr-Yi
PMID: 15919146
Journal: Cell Signal. 2005 Dec;17(12):1572-7.
Title: Ciglitazone-induced p27 gene transcriptional activity is mediated through Sp1 and is negatively regulated by the MAPK signaling pathway.
Author: Chen, Fei|Kim, Eugene|Wang, Chia-Chi|Harrison, Lawrence E
PMID: 15951157
Journal: J Biol Chem. 2005 Sep 9;280(36):32018-25. Epub 2005 Jul 6.
Title: Cyclin-dependent kinase inhibitors uncouple cell cycle progression from mitochondrial apoptotic functions in DNA-damaged cancer cells.
Author: Le, Hong-Van|Minn, Andy J|Massague, Joan
PMID: 16002406
Journal: Am J Pathol. 2005 Oct;167(4):969-80.
Title: Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines: inhibition of JAK3/STAT3 signaling induces apoptosis and cell cycle arrest of colon carcinoma cells.
Author: Lin, Quan|Lai, Raymond|Chirieac, Lucian R|Li, Changping|Thomazy, Vilmos A|Grammatikakis, Ioannis|Rassidakis, George Z|Zhang, Wei|Fujio, Yasushi|Kunisada, Keita|Hamilton, Stanley R|Amin, Hesham M
PMID: 16192633
Journal: Int J Oncol. 2005 Nov;27(5):1391-9.
Title: Indole-3-carbinol inhibits the growth of human colon carcinoma cells but enhances the tumor multiplicity and volume of azoxymethane-induced rat colon carcinogenesis.
Author: Suzui, Masumi|Inamine, Morihiko|Kaneshiro, Tatsuya|Morioka, Takamitsu|Yoshimi, Naoki|Suzuki, Rikako|Kohno, Hiroyuki|Tanaka, Takuji
PMID: 16211236
Journal: Mol Carcinog. 2005 Dec;44(4):293-9.
Title: Artepillin C in Brazilian propolis induces G(0)/G(1) arrest via stimulation of Cip1/p21 expression in human colon cancer cells.
Author: Shimizu, Kazuo|Das, Swadesh K|Hashimoto, Takashi|Sowa, Yoshihiro|Yoshida, Tatsushi|Sakai, Toshiyuki|Matsuura, Yukinaga|Kanazawa, Kazuki
PMID: 16224795
Journal: Biochim Biophys Acta. 2005 Nov 30;1726(3):328-35.
Title: Fucoxanthin induces cell cycle arrest at G0/G1 phase in human colon carcinoma cells through up-regulation of p21WAF1/Cip1.
Author: Das, Swadesh K|Hashimoto, Takashi|Shimizu, Kazuo|Yoshida, Tatsushi|Sakai, Toshiyuki|Sowa, Yoshihiro|Komoto, Akitoshi|Kanazawa, Kazuki
PMID: 16236452
Journal: J Nutr. 2005 Nov;135(11):2710-4.
Title: Dietary components modify gene expression: implications for carcinogenesis.
Author: Yang, Kan|Yang, Wancai|Mariadason, John|Velcich, Anna|Lipkin, Martin|Augenlicht, Leonard
PMID: 16251635
Journal: Int J Cancer. 2006 Feb 1;118(3):600-8.
Title: Proliferation and Cdk4 expression in microsatellite unstable colon cancers with TGFBR2 mutations.
Author: Grady, William M|Willis, Joseph E|Trobridge, Patty|Romero-Gallo, Judith|Munoz, Nina|Olechnowicz, Joseph|Ferguson, Kelly|Gautam, Shiva|Markowitz, Sanford D
PMID: 16108056
Journal: Genome Res. 2006 Feb;16(2):282-9.
Title: Multiplexed profiling of candidate genes for CpG island methylation status using a flexible PCR/LDR/Universal Array assay.
Author: Cheng, Yu-Wei|Shawber, Carrie|Notterman, Dan|Paty, Philip|Barany, Francis
PMID: 16369045
Journal: Oncogene. 2006 May 25;25(22):3123-38.
Title: Protein kinase C delta inhibits Caco-2 cell proliferation by selective changes in cell cycle and cell death regulators.
Author: Cerda, S R|Mustafi, R|Little, H|Cohen, G|Khare, S|Moore, C|Majumder, P|Bissonnette, M
PMID: 16434969
Journal: Int J Cancer. 2006 Jul 1;119(1):74-9.
Title: Truncated APC is required for cell proliferation and DNA replication.
Author: Schneikert, Jean|Behrens, Jurgen
PMID: 16450383
Journal: J Cell Biochem. 2006 Aug 15;98(6):1450-6.
Title: Functional role of VDR in the activation of p27Kip1 by the VDR/Sp1 complex.
Author: Cheng, Hsuen-Tsen|Chen, Jing-Yi|Huang, Yu-Chun|Chang, Hui-Chiu|Hung, Wen-Chun
PMID: 16518840
Journal: Int J Oncol. 2006 Apr;28(4):1003-12.
Title: The antitumor effect of a novel differentiation inducer, 2, 2-Bis (4-(4-amino-3-hydroxyphenoxy) phenyl) adamantane (DPA), in combinatory therapy on human colon cancer.
Author: Wang, Jane-Jen|Lee, Jen-Yi|Chen, Yu-Chen|Chern, Yaw-Terng|Chi, Chin-Wen
PMID: 16525652
Journal: Glycobiology. 2006 Jul;16(7):573-83. Epub 2006 Mar 30.
Title: Ganglioside GM3 modulates tumor suppressor PTEN-mediated cell cycle progression--transcriptional induction of p21(WAF1) and p27(kip1) by inhibition of PI-3K/AKT pathway.
Author: Choi, Hee-Jung|Chung, Tae-Wook|Kang, Sung-Koo|Lee, Young-Choon|Ko, Jeong-Heon|Kim, Jong-Guk|Kim, Cheorl-Ho
PMID: 16574813
Journal: Oncogene. 2006 Sep 7;25(40):5527-36. Epub 2006 Apr 17.
Title: Deletion of the carcinoembryonic antigen-related cell adhesion molecule 1 (Ceacam1) gene contributes to colon tumor progression in a murine model of carcinogenesis.
Author: Leung, N|Turbide, C|Olson, M|Marcus, V|Jothy, S|Beauchemin, N
PMID: 16619040
Journal: Cancer. 2006 Aug 15;107(4):668-75.
Title: Prognostic role of p27Kip1 deregulation in colorectal cancer.
Author: Hershko, Dan D|Shapira, Ma'anit
PMID: 16826582
Journal: Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14009-14.
Title: Testing the importance of p27 degradation by the SCFskp2 pathway in murine models of lung and colon cancer.
Author: Timmerbeul, Inke|Garrett-Engele, Carrie M|Kossatz, Uta|Chen, Xueyan|Firpo, Eduardo|Grunwald, Viktor|Kamino, Kenji|Wilkens, Ludwig|Lehmann, Ulrich|Buer, Jan|Geffers, Robert|Kubicka, Stefan|Manns, Michael P|Porter, Peggy L|Roberts, James M|Malek, Nisar P
PMID: 16966613
Journal: J Med Chem. 2006 Sep 21;49(19):5769-76.
Title: [4-(imidazol-1-yl)thiazol-2-yl]phenylamines. A novel class of highly potent colchicine site binding tubulin inhibitors: synthesis and cytotoxic activity on selected human cancer cell lines.
Author: Mahboobi, Siavosh|Sellmer, Andreas|Hocher, Heymo|Eichhorn, Emerich|Bar, Thomas|Schmidt, Mathias|Maier, Thomas|Stadlwieser, Josef F|Beckers, Thomas L
PMID: 16970401
Journal: World J Gastroenterol. 2006 Sep 21;12(35):5635-43.
Title: Tyrosine kinase of insulin-like growth factor receptor as target for novel treatment and prevention strategies of colorectal cancer.
Author: Hopfner, Michael|Sutter, Andreas P|Huether, Alexander|Baradari, Viola|Scherubl, Hans
PMID: 17007015
Journal: World J Gastroenterol. 2006 Oct 21;12(39):6299-304.
Title: Cytoplasmic expression of p27(kip1) is associated with a favourable prognosis in colorectal cancer patients.
Author: Watson, Nicholas F S|Durrant, Lindy G|Scholefield, John H|Madjd, Zahra|Scrimgeour, Duncan|Spendlove, Ian|Ellis, Ian O|Patel, Poulam M
PMID: 17072952
Journal: World J Gastroenterol. 2006 Dec 7;12(45):7263-70.
Title: Effect of ligand troglitazone on peroxisome proliferator-activated receptor gamma expression and cellular growth in human colon cancer cells.
Author: Ming, Mei|Yu, Jie-Ping|Meng, Xiang-Zhi|Zhou, Yan-Hong|Yu, Hong-Gang|Luo, He-Sheng
PMID: 17143939
Journal: Cancer Res. 2006 Dec 15;66(24):11623-31.
Title: Up-regulation of GPR48 induced by down-regulation of p27Kip1 enhances carcinoma cell invasiveness and metastasis.
Author: Gao, Yun|Kitagawa, Kyoko|Hiramatsu, Yoshihiro|Kikuchi, Hirotoshi|Isobe, Tomoyasu|Shimada, Mai|Uchida, Chiharu|Hattori, Takayuki|Oda, Toshiaki|Nakayama, Keiko|Nakayama, Keiichi I|Tanaka, Tatsuo|Konno, Hiroyuki|Kitagawa, Masatoshi
PMID: 17178856
Journal: Mod Pathol. 2007 Jan;20(1):15-22. Epub 2006 Nov 3.
Title: Loss of nuclear p27 (CDKN1B/KIP1) in colorectal cancer is correlated with microsatellite instability and CIMP.
Author: Ogino, Shuji|Kawasaki, Takako|Kirkner, Gregory J|Yamaji, Taiki|Loda, Massimo|Fuchs, Charles S
PMID: 17086168
Journal: Hum Pathol. 2007 Apr;38(4):585-92. Epub 2007 Jan 19.
Title: Cytoplasmic localization of p27 (cyclin-dependent kinase inhibitor 1B/KIP1) in colorectal cancer: inverse correlations with nuclear p27 loss, microsatellite instability, and CpG island methylator phenotype.
Author: Ogino, Shuji|Kawasaki, Takako|Ogawa, Akiyo|Kirkner, Gregory J|Loda, Massimo|Fuchs, Charles S
PMID: 17239930
Journal: J Cell Physiol. 2007 Jul;212(1):42-50.
Title: In vitro differentiation of HT-29 M6 mucus-secreting colon cancer cells involves a trychostatin A and p27(KIP1)-inducible transcriptional program of gene expression.
Author: Mayo, Clara|Lloreta, Josep|Real, Francisco X|Mayol, Xavier
PMID: 17311291
Journal: Oncogene. 2007 Oct 18;26(48):6954-8. Epub 2007 May 7.
Title: p21(Waf1/Cip1/Sdi1) mediates retinoblastoma protein degradation.
Author: Broude, E V|Swift, M E|Vivo, C|Chang, B-D|Davis, B M|Kalurupalle, S|Blagosklonny, M V|Roninson, I B
PMID: 17486059
Journal: Cancer Res. 2007 Jun 1;67(11):5248-57.
Title: Chemoresistant KM12C colon cancer cells are addicted to low cyclic AMP levels in a phosphodiesterase 4-regulated compartment via effects on phosphoinositide 3-kinase.
Author: McEwan, David G|Brunton, Valerie G|Baillie, George S|Leslie, Nicholas R|Houslay, Miles D|Frame, Margaret C
PMID: 17545604
Journal: Cancer Res. 2007 Aug 15;67(16):7773-81.
Title: Regulation of PTEN expression in intestinal epithelial cells by c-Jun NH2-terminal kinase activation and nuclear factor-kappaB inhibition.
Author: Wang, Qingding|Zhou, Yuning|Wang, Xiaofu|Chung, Dai H|Evers, B Mark
PMID: 17699782
Journal: Cancer Sci. 2007 Nov;98(11):1809-16. Epub 2007 Sep 2.
Title: Identification of JTP-70902, a p15(INK4b)-inductive compound, as a novel MEK1/2 inhibitor.
Author: Yamaguchi, Takayuki|Yoshida, Takayuki|Kurachi, Reina|Kakegawa, Junya|Hori, Yoshikazu|Nanayama, Toyomichi|Hayakawa, Kazuhide|Abe, Hiroyuki|Takagi, Koichi|Matsuzaki, Youichirou|Koyama, Makoto|Yogosawa, Shingo|Sowa, Yoshihiro|Yamori, Takao|Tajima, Nobuyuki|S
PMID: 17784872
Journal: Dis Colon Rectum. 2007 Nov;50(11):1887-98.
Title: Survival stratification panel of colorectal carcinoma with combined expression of carcinoembryonic antigen, matrix metalloproteinases-2, and p27 kip1.
Author: Li, Ming|Li, Ji-You|Zhao, Ai-Lian|He, Jing-Sheng|Zhou, Li-Xin|Li, Ying-Ai|Gu, Jin
PMID: 17882488
Journal: Oncology. 2007;73(1-2):52-7.
Title: Colorectal cancer or colon and rectal cancer? Clinicopathological comparison between colonic and rectal carcinomas.
Author: Li, M|Li, J Y|Zhao, A L|Gu, J
PMID: 18334831
Journal: J Pathol. 2008 Feb;214(3):320-7.
Title: BRAF provides proliferation and survival signals in MSI colorectal carcinoma cells displaying BRAF(V600E) but not KRAS mutations.
Author: Preto, A|Figueiredo, J|Velho, S|Ribeiro, A S|Soares, P|Oliveira, C|Seruca, R
PMID: 18098337
Journal: Int J Cancer. 2008 May 1;122(9):2115-24.
Title: Combination of atorvastatin and celecoxib synergistically induces cell cycle arrest and apoptosis in colon cancer cells.
Author: Xiao, Hang|Zhang, Qiang|Lin, Yong|Reddy, Bandaru S|Yang, Chung S
PMID: 18172863
Journal: Neoplasia. 2008 Mar;10(3):287-97.
Title: Inhibition of JAK1, 2/STAT3 signaling induces apoptosis, cell cycle arrest, and reduces tumor cell invasion in colorectal cancer cells.
Author: Xiong, Hua|Zhang, Zhi-Gang|Tian, Xiao-Qing|Sun, Dan-Feng|Liang, Qin-Chuan|Zhang, Yan-Jie|Lu, Rong|Chen, Ying-Xuan|Fang, Jing-Yuan
PMID: 18320073
Journal: Cell Death Differ. 2008 May;15(5):908-19.
Title: p27 Kip1 nuclear localization and cyclin-dependent kinase inhibitory activity are regulated by glycogen synthase kinase-3 in human colon cancer cells.
Author: Wang, Q|Zhou, Y|Wang, X|Evers, B M
PMID: 18408738
Journal: Br J Pharmacol. 2008 Jun;154(3):632-8.
Title: Bone morphogenetic protein signalling is required for the anti-mitogenic effect of the proteasome inhibitor MG-132 on colon cancer cells.
Author: Wu, W K K|Sung, J J Y|Wu, Y C|Li, Z J|Yu, L|Cho, C H
PMID: 18414391
Journal: Cancer Res. 2008 May 1;68(9):3379-88.
Title: Bortezomib (Velcade) induces p27Kip1 expression through S-phase kinase protein 2 degradation in colorectal cancer.
Author: Uddin, Shahab|Ahmed, Maqbool|Bavi, Prashant|El-Sayed, Raafat|Al-Sanea, Nasser|AbdulJabbar, Alaa|Ashari, Luai H|Alhomoud, Samar|Al-Dayel, Fouad|Hussain, Azhar R|Al-Kuraya, Khawla S
PMID: 18451165
Journal: Int J Clin Pharmacol Ther. 2008 May;46(5):226-35.
Title: Mucronulatol from Caribbean propolis exerts cytotoxic effects on human tumor cell lines.
Author: Diaz-Carballo, D|Freista Hler, M|Malak, S|Bardenheuer, W|Reusch, H P
PMID: 18538108
Journal: Carcinogenesis. 2008 Jul;29(7):1435-40.
Title: Genetic deficiency of decorin causes intestinal tumor formation through disruption of intestinal cell maturation.
Author: Bi, Xiuli|Tong, Chang|Dockendorff, Ashley|Bancroft, Laura|Gallagher, Lindsay|Guzman, Grace|Iozzo, Renato V|Augenlicht, Leonard H|Yang, Wancai
PMID: 18550571
Journal: Cancer Res. 2008 Jul 1;68(13):5355-62.
Title: Activation of protein kinase G Increases the expression of p21CIP1, p27KIP1, and histidine triad protein 1 through Sp1.
Author: Cen, Bo|Deguchi, Atsuko|Weinstein, I Bernard
PMID: 18593937
Journal: J Exp Med. 2008 Sep 1;205(9):2163-75.
Title: A critical role for Apc in hematopoietic stem and progenitor cell survival.
Author: Qian, Zhijian|Chen, Lina|Fernald, Anthony A|Williams, Bart O|Le Beau, Michelle M
PMID: 18725524
Journal: World J Gastroenterol. 2008 Oct 14;14(38):5827-33.
Title: Antitumor bioactivity of adenovirus-mediated p27mt in colorectal cancer cell line SW480.
Author: Sun, Ze-Qun|Deng, Chang-Sheng|Xu, Shao-Yong|Du, Yong
PMID: 18855981
Journal: Int J Clin Pract. 2008 Nov;62(11):1736-43.
Title: Expression patterns of cyclins D1, E and cyclin-dependent kinase inhibitors p21waf1/cip1, p27kip1 in colorectal carcinoma: correlation with other cell cycle regulators (pRb, p53 and Ki-67 and PCNA) and clinicopathological features.
Author: Ioachim, E
PMID: 19143860
Journal: Int J Cancer. 2009 Mar 15;124(6):1322-9.
Title: N6-isopentenyladenosine inhibits cell proliferation and induces apoptosis in a human colon cancer cell line DLD1.
Author: Laezza, Chiara|Caruso, Maria Gabriella|Gentile, Teresa|Notarnicola, Maria|Malfitano, Anna Maria|Di Matola, Tiziana|Messa, Caterina|Gazzerro, Patrizia|Bifulco, Maurizio
PMID: 19058178
Journal: Int J Oncol. 2009 Jan;34(1):69-77.
Title: p27Kip1 is inactivated in human colorectal cancer by cytoplasmic localization associated with activation of Akt/PKB.
Author: Bottini, C|Platini, F|Rinaldi, M|Leutner, M|Alabiso, O|Garavoglia, M|Tessitore, L
PMID: 19082479
Journal: Biochem Biophys Res Commun. 2009 Apr 24;382(1):79-84.
Title: Inhibition of cyclooxygenase-1 lowers proliferation and induces macroautophagy in colon cancer cells.
Author: Wu, William Ka Kei|Sung, Joseph Jao Yiu|Wu, Ya Chun|Li, Hai To|Yu, Le|Li, Zhi Jie|Cho, Chi Hin
PMID: 19258012
Journal: Clin Cancer Res. 2009 Mar 15;15(6):2116-22.
Title: p27Kip1 in stage III colon cancer: implications for outcome following adjuvant chemotherapy in cancer and leukemia group B protocol 89803.
Author: Bertagnolli, Monica M|Warren, Robert S|Niedzwiecki, Donna|Mueller, Elke|Compton, Carolyn C|Redston, Mark|Hall, Margaret|Hahn, Hejin P|Jewell, Scott D|Mayer, Robert J|Goldberg, Richard M|Saltz, Leonard B|Loda, Massimo
PMID: 19276255
Journal: Lab Invest. 2009 Jun;89(6):717-25.
Title: Inhibition of STAT5 induces G1 cell cycle arrest and reduces tumor cell invasion in human colorectal cancer cells.
Author: Xiong, Hua|Su, Wen-Yu|Liang, Qin-Chuan|Zhang, Zhi-Gang|Chen, Hui-Min|Du, Wan|Chen, Ying-Xuan|Fang, Jing-Yuan
PMID: 19290007
Journal: Cancer Gene Ther. 2009 Nov;16(11):810-9.
Title: RNA interference-mediated knockdown of p21(WAF1) enhances anti-tumor cell activity of oncolytic adenoviruses.
Author: Shiina, M|Lacher, M D|Christian, C|Korn, W M
PMID: 19407849
Journal: Cancer Epidemiol Biomarkers Prev. 2009 Jun;18(6):1849-58.
Title: A cohort study of p27 localization in colon cancer, body mass index, and patient survival.
Author: Ogino, Shuji|Shima, Kaori|Nosho, Katsuhiko|Irahara, Natsumi|Baba, Yoshifumi|Wolpin, Brian M|Giovannucci, Edward L|Meyerhardt, Jeffrey A|Fuchs, Charles S
PMID: 19505918
Journal: J Biol Chem. 2009 Aug 21;284(34):22916-25.
Title: Mirk regulates the exit of colon cancer cells from quiescence.
Author: Jin, Kideok|Ewton, Daina Z|Park, Sunju|Hu, Jing|Friedman, Eileen
PMID: 19542220
Journal: Clin Cancer Res. 2009 Jul 1;15(13):4431-8.
Title: A cohort study of cyclin D1 expression and prognosis in 602 colon cancer cases.
Author: Ogino, Shuji|Nosho, Katsuhiko|Irahara, Natsumi|Kure, Shoko|Shima, Kaori|Baba, Yoshifumi|Toyoda, Saori|Chen, Li|Giovannucci, Edward L|Meyerhardt, Jeffrey A|Fuchs, Charles S
PMID: 19549773
Journal: J Cell Physiol. 2009 Nov;221(2):350-8.
Title: E2F4 expression is required for cell cycle progression of normal intestinal crypt cells and colorectal cancer cells.
Author: Garneau, Hugo|Paquin, Marie-Christine|Carrier, Julie C|Rivard, Nathalie
PMID: 19562678
Journal: Cancer Res. 2009 Aug 1;69(15):6100-6.
Title: Tumor repressive functions of estrogen receptor beta in SW480 colon cancer cells.
Author: Hartman, Johan|Edvardsson, Karin|Lindberg, Karolina|Zhao, Chunyan|Williams, Cecilia|Strom, Anders|Gustafsson, Jan-Ake
PMID: 19602591
Journal: Biochem Biophys Res Commun. 2009 Oct 30;388(4):752-6.
Title: Schlafen-3: a novel regulator of intestinal differentiation.
Author: Patel, Vaishali B|Yu, Yingjie|Das, Jayanta K|Patel, Bhaumik B|Majumdar, Adhip P N
PMID: 19703412
Journal: J Pathol. 2009 Dec;219(4):435-45.
Title: Prognostic significance of alterations in KRAS isoforms KRAS-4A/4B and KRAS mutations in colorectal carcinoma.
Author: Abubaker, Jehad|Bavi, Prashant|Al-Haqawi, Wael|Sultana, Mehar|Al-Harbi, Sayer|Al-Sanea, Nasser|Abduljabbar, Alaa|Ashari, Luai H|Alhomoud, Samar|Al-Dayel, Fouad|Uddin, Shahab|Al-Kuraya, Khawla S
PMID: 19824059
Journal: Oncol Rep. 2009 Dec;22(6):1435-41.
Title: Depletion of PI3K p85alpha induces cell cycle arrest and apoptosis in colorectal cancer cells.
Author: Sun, Yan|Zhao, Shiyi|Tian, Hua|Xie, Xiaoyun|Xiao, Faman|Li, Kang|Song, Yugang
PMID: 19885597
Journal: J Cell Mol Med. 2009 Sep;13(9B):3668-79.
Title: Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signalling.
Author: Xiong, Hua|Chen, Zhao-Fei|Liang, Qin-Chuan|Du, Wan|Chen, Hui-Min|Su, Wen-Yu|Chen, Guo-Qiang|Han, Ze-Guang|Fang, Jing-Yuan
PMID: 20196786
Journal: Gastroenterology. 2010 Jan;138(1):231-40.e1-5.
Title: RNA-binding protein quaking, a critical regulator of colon epithelial differentiation and a suppressor of colon cancer.
Author: Yang, Guodong|Fu, Haiyan|Zhang, Jie|Lu, Xiaozhao|Yu, Fang|Jin, Liang|Bai, Liyuan|Huang, Bo|Shen, Lan|Feng, Yue|Yao, Libo|Lu, Zifan
PMID: 19686745
Journal: Cell Commun Signal. 2010 Feb 2;8(1):1.
Title: High Erk activity suppresses expression of the cell cycle inhibitor p27Kip1 in colorectal cancer cells.
Author: Kress, Theresia R|Raabe, Thomas|Feller, Stephan M
PMID: 20181064
Journal: Mol Cancer Res. 2010 May;8(5):798-805.
Title: STAT1 represses Skp2 gene transcription to promote p27Kip1 stabilization in Ras-transformed cells.
Author: Wang, Shuo|Raven, Jennifer F|Koromilas, Antonis E
PMID: 20407011
Journal: BMC Cancer. 2010 Jul 15;10:370.
Title: Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells.
Author: Sasaki, Kazuhito|Tsuno, Nelson H|Sunami, Eiji|Tsurita, Giichiro|Kawai, Kazushige|Okaji, Yurai|Nishikawa, Takeshi|Shuno, Yasutaka|Hongo, Kumiko|Hiyoshi, Masaya|Kaneko, Manabu|Kitayama, Joji|Takahashi, Koki|Nagawa, Hirokazu
PMID: 20630104
Journal: Mol Cancer. 2010 Jul 30;9:203.
Title: Prognostic significance of TRAIL death receptors in Middle Eastern colorectal carcinomas and their correlation to oncogenic KRAS alterations.
Author: Bavi, Prashant|Prabhakaran, Sarita E|Abubaker, Jehad|Qadri, Zeeshan|George, Thara|Al-Sanea, Nasser|Abduljabbar, Alaa|Ashari, Luai H|Alhomoud, Samar|Al-Dayel, Fouad|Hussain, Azhar R|Uddin, Shahab|Al-Kuraya, Khawla S
PMID: 20673328
Journal: Nutr Res Pract. 2010 Oct;4(5):351-5.
Title: Significance of p27 as potential biomarker for intracellular oxidative status.
Author: Quintos, Lesley|Lee, In Ae|Kim, Hyo Jung|Lim, Ji-Sun|Park, Jia|Sung, Mi-Kyung|Seo, Young Rok|Kim, Jong-Sang
PMID: 21103079
Journal: Evid Based Complement Alternat Med. 2011;2011:984027.
Title: Inhibition of Anchorage-Independent Proliferation and G0/G1 Cell-Cycle Regulation in Human Colorectal Carcinoma Cells by 4,7-Dimethoxy-5-Methyl-l,3-Benzodioxole Isolated from the Fruiting Body of Antrodia camphorate.
Author: Lien, Hsiu-Man|Lin, Hsiao-Wei|Wang, Ying-Jan|Chen, Li-Ching|Yang, Ding-Yah|Lai, Ya-Yun|Ho, Yuan-Soon
PMID: 19293251
Journal: Int J Cancer. 2011 Mar 1;128(5):1080-94.
Title: Prognostic significance of CDKN2A (p16) promoter methylation and loss of expression in 902 colorectal cancers: Cohort study and literature review.
Author: Shima, Kaori|Nosho, Katsuhiko|Baba, Yoshifumi|Cantor, Mami|Meyerhardt, Jeffrey A|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji
PMID: 20473920
Journal: Med Oncol. 2011 Dec;28(4):1495-506.
Title: Down-regulation of phospho-non-receptor Src tyrosine kinases contributes to growth inhibition of cervical cancer cells.
Author: Kong, Lu|Deng, Zhihong|Zhao, Yanzhong|Wang, Yamei|Sarkar, Fazlul H|Zhang, Yuxiang
PMID: 20532678
Journal: Mol Carcinog. 2011 Jan;50(1):8-15.
Title: Expression analysis of proline rich 15 (Prr15) in mouse and human gastrointestinal tumors.
Author: Meunier, Dominique|Patra, Kalicharan|Smits, Ron|Hagebarth, Andrea|Luttges, Angela|Jaussi, Rolf|Wieduwilt, Matthew J|Quintanilla-Fend, Leticia|Himmelbauer, Heinz|Fodde, Riccardo|Fundele, Reinald H
PMID: 21061267
Journal: Am J Physiol Gastrointest Liver Physiol. 2011 Feb;300(2):G264-72.
Title: Tumor suppressor FOXO3 mediates signals from the EGF receptor to regulate proliferation of colonic cells.
Author: Qi, Wentao|Weber, Christopher R|Wasland, Kaarin|Roy, Hemant|Wali, Ramesh|Joshi, Suhasini|Savkovic, Suzana D
PMID: 21109589
Journal: Oncol Rep. 2011 Jan;25(1):223-30.
Title: Esculetin inhibits cell proliferation through the Ras/ERK1/2 pathway in human colon cancer cells.
Author: Park, Sung-Suk|Park, Sung-Kyu|Lim, Jung-Hyurk|Choi, Yung Hyun|Kim, Wun-Jae|Moon, Sung-Kwon
PMID: 21109980
Journal: Cancer Res. 2011 Jan 15;71(2):593-602.
Title: Suppression of colonic polyposis by homeoprotein CDX2 through its nontranscriptional function that stabilizes p27Kip1.
Author: Aoki, Koji|Kakizaki, Fumihiko|Sakashita, Hiromi|Manabe, Toshiaki|Aoki, Masahiro|Taketo, Makoto M
PMID: 21224344
Journal: Cancer Chemother Pharmacol. 2011 Oct;68(4):871-8.
Title: Cetuximab enhances the activities of irinotecan on gastric cancer cell lines through downregulating the EGFR pathway upregulated by irinotecan.
Author: Liu, Xin|Guo, Wei-Jian|Zhang, Xiao-Wei|Cai, Xu|Tian, Shu|Li, Jin
PMID: 21286718
Journal: Hum Pathol. 2011 Jul;42(7):1047-52.
Title: A novel case of rhabdoid colon carcinoma associated with a positive CpG island methylator phenotype and BRAF mutation.
Author: Pancione, Massimo|Di Blasi, Arturo|Sabatino, Lina|Fucci, Alessandra|Dalena, Anna Maria|Palombi, Natalia|Carotenuto, Pietro|Aquino, Gabriella|Daniele, Bruno|Normanno, Nicola|Colantuoni, Vittorio
PMID: 21315413
Journal: J Surg Res. 2011 May 15;167(2):231-6.
Title: Do young patients with colorectal cancer have a poorer prognosis than old patients?
Author: Li, Ming|Li, Ji-You|Zhao, Ai-Lian|Gu, Jin
PMID: 21316708
Journal: Med Hypotheses. 2011 May;76(5):697-9.
Title: Modulation of liver X receptor signaling as a prevention and therapy for colon cancer.
Author: Chuu, Chih-Pin
PMID: 21333456
Journal: J Clin Invest. 2011 Mar;121(3):866-79.
Title: Hunk is required for HER2/neu-induced mammary tumorigenesis.
Author: Yeh, Elizabeth S|Yang, Thomas W|Jung, Jason J|Gardner, Heather P|Cardiff, Robert D|Chodosh, Lewis A
PMID: 21393859
Journal: Clin Cancer Res. 2011 Jun 1;17(11):3569-78.
Title: HOXB7 as a prognostic factor and mediator of colorectal cancer progression.
Author: Liao, Wen-Ting|Jiang, Dan|Yuan, Jian|Cui, Yan-Mei|Shi, Xi-Wen|Chen, Cui-Min|Bian, Xiu-Wu|Deng, Yong-Jian|Ding, Yan-Qing
PMID: 21474578
Journal: Int J Oncol. 2011 Jul;39(1):23-31.
Title: Antitumor activities of JTP-74057 (GSK1120212), a novel MEK1/2 inhibitor, on colorectal cancer cell lines in vitro and in vivo.
Author: Yamaguchi, Takayuki|Kakefuda, Reina|Tajima, Nobuyuki|Sowa, Yoshihiro|Sakai, Toshiyuki
PMID: 21523318
Journal: PLoS One. 2011;6(5):e20098.
Title: Thermostable direct hemolysin downregulates human colon carcinoma cell proliferation with the involvement of E-cadherin, and beta-catenin/Tcf-4 signaling.
Author: Chowdhury, Pinki|Pore, Debasis|Mahata, Nibedita|Karmakar, Poulomee|Pal, Amit|Chakrabarti, Manoj K
PMID: 21625458
Journal: BMC Cancer. 2011 Jun 3;11:219.
Title: Genistein inhibits proliferation of colon cancer cells by attenuating a negative effect of epidermal growth factor on tumor suppressor FOXO3 activity.
Author: Qi, Wentao|Weber, Christopher R|Wasland, Kaarin|Savkovic, Suzana D
PMID: 21639915
Journal: Anticancer Drugs. 2012 Feb;23(2):191-9.
Title: B1, a novel topoisomerase II inhibitor, induces apoptosis and cell cycle G1 arrest in lung adenocarcinoma A549 cells.
Author: Cheng, Meng-Hsuan|Yang, Yu-Chiao|Wong, Yun-Hong|Chen, Tsuei-Ru|Lee, Chia-Yu|Yang, Chun-Chien|Chen, Shih-Hua|Yang, I-Ning|Yang, Ya-Shiu|Huang, Hsu-Shan|Yang, Chun-Yuh|Huang, Ming-Shyan|Chiu, Hui-Fen
PMID: 22008852
Journal: Cell Signal. 2012 Mar;24(3):718-25.
Title: Stat6 activity-related Th2 cytokine profile and tumor growth advantage of human colorectal cancer cells in vitro and in vivo.
Author: Li, Ben Hui|Xu, Shuang Bing|Li, Feng|Zou, Xiao Guang|Saimaiti, Abudukeyoumu|Simayi, Dilixia|Wang, Ying Hong|Zhang, Yan|Yuan, Jia|Zhang, Wen Jie
PMID: 22108090
Journal: Oncogene. 2012 Sep 13;31(37):4128-38.
Title: Involvement of the SKP2-p27(KIP1) pathway in suppression of cancer cell proliferation by RECK.
Author: Yoshida, Y|Ninomiya, K|Hamada, H|Noda, M
PMID: 22158033
Journal: Carcinogenesis. 2012 Feb;33(2):326-30.
Title: Decorin-mediated inhibition of colorectal cancer growth and migration is associated with E-cadherin in vitro and in mice.
Author: Bi, Xiuli|Pohl, Nicole M|Qian, Zhibin|Yang, George R|Gou, Yuan|Guzman, Grace|Kajdacsy-Balla, Andre|Iozzo, Renato V|Yang, Wancai
PMID: 22159220
Journal: J Agric Food Chem. 2012 Apr 11;60(14):3612-8.
Title: In vivo antitumor effects of 4,7-dimethoxy-5-methyl-1,3-benzodioxole isolated from the fruiting body of Antrodia camphorata through activation of the p53-mediated p27/Kip1 signaling pathway.
Author: Tu, Shih-Hsin|Wu, Chih-Hsiung|Chen, Li-Ching|Huang, Ching-Shui|Chang, Hui-Wen|Chang, Chien-Hsi|Lien, Hsiu-Man|Ho, Yuan-Soon
PMID: 22429157
Journal: Cancer Res. 2012 Jun 15;72(12):3020-8.
Title: Postmenopausal hormone therapy is associated with a reduced risk of colorectal cancer lacking CDKN1A expression.
Author: Lin, Jennifer H|Morikawa, Teppei|Chan, Andrew T|Kuchiba, Aya|Shima, Kaori|Nosho, Katsuhiko|Kirkner, Gregory|Zhang, Shumin M|Manson, Joann E|Giovannucci, Edward|Fuchs, Charles S|Ogino, Shuji
PMID: 22511578
Journal: Evid Based Complement Alternat Med. 2012;2012:326096.
Title: 6-Gingerol Inhibits Growth of Colon Cancer Cell LoVo via Induction of G2/M Arrest.
Author: Lin, Ching-Bin|Lin, Chun-Che|Tsay, Gregory J
PMID: 22719783
Journal: Mol Nutr Food Res. 2012 Oct;56(10):1520-31.
Title: Concomitant consumption of lycopene and fish oil inhibits tumor growth and progression in a mouse xenograft model of colon cancer.
Author: Tang, Feng-Yao|Pai, Man-Hui|Kuo, Yueh-Hsiung|Wang, Xiang-Dong
PMID: 22961879
Journal: PLoS One. 2012;7(9):e44502.
Title: Phosphorylation and subcellular localization of p27Kip1 regulated by hydrogen peroxide modulation in cancer cells.
Author: Ibanez, Irene L|Bracalente, Candelaria|Notcovich, Cintia|Tropper, Ivanna|Molinari, Beatriz L|Policastro, Lucia L|Duran, Hebe
PMID: 22970236
Journal: PLoS One. 2012;7(9):e45617.
Title: Inhibition of Tcf-4 induces apoptosis and enhances chemosensitivity of colon cancer cells.
Author: Xie, Jiang|Xiang, De-Bing|Wang, Hong|Zhao, Cong|Chen, Jie|Xiong, Feng|Li, Ting-Yu|Wang, Xiao-Lei
PMID: 23029137
Journal: J Cancer Res Ther. 2012 Oct-Dec;8(4):532-6.
Title: The in vivo antitumor effects on human COLO 205 cancer cells of the 4,7-dimethoxy-5-(2-propen-1-yl)-1,3-benzodioxole (apiole) derivative of 5-substituted 4,7-dimethoxy-5-methyl-l,3-benzodioxole (SY-1) isolated from the fruiting body of Antrodia camphorate
Author: Wei, Po-Li|Tu, Shih-Hsin|Lien, Hsiu-Man|Chen, Li-Ching|Chen, Ching-Shyang|Wu, Chih-Hsiung|Huang, Ching-Shui|Chang, Hui-Wen|Chang, Chien-Hsi|Tseng, How|Ho, Yuan-Soon
PMID: 23361270
Journal: Gut. 2013 May;62(5):716-26.
Title: miR-574-5p negatively regulates Qki6/7 to impact beta-catenin/Wnt signalling and the development of colorectal cancer.
Author: Ji, Shunlong|Ye, Gengtai|Zhang, Jun|Wang, Linpei|Wang, Tao|Wang, Zhen|Zhang, Tiantian|Wang, Guanghui|Guo, Zongsheng|Luo, Yu|Cai, Jianchun|Yang, James Y
PMID: 22490519
Journal: Int J Cancer. 2013 Feb 1;132(3):707-16.
Title: Antitumor effects of novel compound, guttiferone K, on colon cancer by p21Waf1/Cip1-mediated G(0) /G(1) cell cycle arrest and apoptosis.
Author: Kan, Winnie Lai Ting|Yin, Chun|Xu, Hong Xi|Xu, Gang|To, Kenneth Kin Wah|Cho, Chi Hin|Rudd, John Anthony|Lin, Ge
PMID: 22733377
Journal: Int J Oncol. 2013 Jan;42(1):161-7.
Title: SSEA-3 as a novel amplifying cancer cell surface marker in colorectal cancers.
Author: Suzuki, Yozo|Haraguchi, Naotsugu|Takahashi, Hidekazu|Uemura, Mamoru|Nishimura, Junichi|Hata, Taishi|Takemasa, Ichiro|Mizushima, Tsunekazu|Ishii, Hideshi|Doki, Yuichiro|Mori, Masaki|Yamamoto, Hirofumi
PMID: 23175153
Journal: Cell Physiol Biochem. 2013;31(1):113-22.
Title: External Qi of Yan Xin Qigong inhibits activation of Akt, Erk1/2 and NF-kB and induces cell cycle arrest and apoptosis in colorectal cancer cells.
Author: Yan, Xin|Shen, Hua|Jiang, Hongjian|Hu, Dan|Wang, Jun|Wu, Xinqi
PMID: 23363659
Journal: PLoS One. 2013;8(2):e55904.
Title: Differential roles of Hath1, MUC2 and P27Kip1 in relation with gamma-secretase inhibition in human colonic carcinomas: a translational study.
Author: Souaze, Frederique|Bou-Hanna, Chantal|Kandel, Christine|Leclair, Francois|Devalliere, Julie|Charreau, Beatrice|Bezieau, Stephane|Mosnier, Jean-Francois|Laboisse, Christian L
PMID: 23409082
Journal: J Agric Food Chem. 2013 Mar 20;61(11):2811-9.
Title: P27/Kip1 is responsible for magnolol-induced U373 apoptosis in vitro and in vivo.
Author: Chen, Li-Ching|Lee, Wen-Sen
PMID: 23448150
Journal: Mol Cancer Res. 2013 Jul;11(7):689-98.
Title: Interactions between SAP155 and FUSE-binding protein-interacting repressor bridges c-Myc and P27Kip1 expression.
Author: Matsushita, Kazuyuki|Tamura, Mai|Tanaka, Nobuko|Tomonaga, Takeshi|Matsubara, Hisahiro|Shimada, Hideaki|Levens, David|He, Liusheng|Liu, Juhong|Yoshida, Minoru|Nomura, Fumio
PMID: 23594796
Journal: J Biol Chem. 2013 Jun 7;288(23):16274-81.
Title: FOXO3 growth inhibition of colonic cells is dependent on intraepithelial lipid droplet density.
Author: Qi, Wentao|Fitchev, Philip S|Cornwell, Mona L|Greenberg, Jordan|Cabe, Maleen|Weber, Christopher R|Roy, Hemant K|Crawford, Susan E|Savkovic, Suzana D
PMID: 23603907
Journal: Cancer Epidemiol Biomarkers Prev. 2013 Jun;22(6):1142-52.
Title: Physical activity, tumor PTGS2 expression, and survival in patients with colorectal cancer.
Author: Yamauchi, Mai|Lochhead, Paul|Imamura, Yu|Kuchiba, Aya|Liao, Xiaoyun|Qian, Zhi Rong|Nishihara, Reiko|Morikawa, Teppei|Shima, Kaori|Wu, Kana|Giovannucci, Edward|Meyerhardt, Jeffrey A|Fuchs, Charles S|Chan, Andrew T|Ogino, Shuji
PMID: 23629521
Journal: Clin Cancer Res. 2013 Sep 1;19(17):4662-72.
Title: microRNA-224 promotes cell proliferation and tumor growth in human colorectal cancer by repressing PHLPP1 and PHLPP2.
Author: Liao, Wen-Ting|Li, Ting-Ting|Wang, Zheng-Gen|Wang, Shu-Yang|He, Mei-Rong|Ye, Ya-Ping|Qi, Lu|Cui, Yan-Mei|Wu, Ping|Jiao, Hong-Li|Zhang, Chi|Xie, Yi-Jun|Wang, Jun-Xian|Ding, Yan-Qing
PMID: 23846336
Journal: Chem Biol Interact. 2013 Nov 25;206(2):222-9.
Title: Activation of P27kip1-cyclin D1/E-CDK2 pathway by polysaccharide from Phellinus linteus leads to S-phase arrest in HT-29 cells.
Author: Zhong, Shi|Ji, Dong-Feng|Li, You-Gui|Lin, Tian-Bao|Lv, Zhi-Qiang|Chen, Hua-Ping
PMID: 24060681
Journal: J Cell Physiol. 2014 Jun;229(6):772-82.
Title: MicroRNA-200b stimulates tumour growth in TGFBR2-null colorectal cancers by negatively regulating p27/kip1.
Author: Fu, Yuxuan|Liu, Xianghua|Zhou, Ningtian|Du, Lijian|Sun, Yu|Zhang, Xiang|Ge, Yingbin
PMID: 24151081
Journal: Int J Cancer. 2014 Dec 1;135(11):2528-36.
Title: Statins inhibit tumor progression via an enhancer of zeste homolog 2-mediated epigenetic alteration in colorectal cancer.
Author: Ishikawa, S|Hayashi, H|Kinoshita, K|Abe, M|Kuroki, H|Tokunaga, R|Tomiyasu, S|Tanaka, H|Sugita, H|Arita, T|Yagi, Y|Watanabe, M|Hirota, M|Baba, H
PMID: 24346863
Journal: Oncotarget. 2014 May 15;5(9):2404-17.
Title: Alternative splicing of FBP-interacting repressor coordinates c-Myc, P27Kip1/cyclinE and Ku86/XRCC5 expression as a molecular sensor for bleomycin-induced DNA damage pathway.
Author: Rahmutulla, Bahityar|Matsushita, Kazuyuki|Satoh, Mamoru|Seimiya, Masanori|Tsuchida, Sachio|Kubo, Shuji|Shimada, Hideaki|Ohtsuka, Masayuki|Miyazaki, Masaru|Nomura, Fumio
PMID: 24811221
Journal: Zhonghua Yi Xue Za Zhi. 2014 Apr 1;94(12):899-902.
Title: [Expression and significance of c-Jun activation domain binding protein 1 in human colorectal carcinoma].
Author: Guo, Zhiqin|Lu, Qingshan|Zhang, Yanping|Wang, Zhen|Wen, Xiaowei|Yao, Ming|Wu, Wanxin
PMID: 24854908
Journal: Mol Cancer. 2014 May 26;13:124.
Title: microRNA-139-5p exerts tumor suppressor function by targeting NOTCH1 in colorectal cancer.
Author: Zhang, Lijing|Dong, Yujuan|Zhu, Nana|Tsoi, Ho|Zhao, Zengren|Wu, Chung Wah|Wang, Kunning|Zheng, Shu|Ng, Simon Sm|Chan, Francis Kl|Sung, Joseph Jy|Yu, Jun
PMID: 24885920
Journal: Oncotarget. 2014 Jun 15;5(11):3813-22.
Title: Brachyury regulates proliferation of cancer cells via a p27Kip1-dependent pathway.
Author: Jezkova, Jana|Williams, Jason S|Jones-Hutchins, Ffion|Sammut, Stephen J|Gollins, Simon|Cree, Ian|Coupland, Sarah|McFarlane, Ramsay J|Wakeman, Jane A
PMID: 25003467
Journal: Int J Oncol. 2014 Oct;45(4):1583-93.
Title: Deficient HER3 expression in poorly-differentiated colorectal cancer cells enhances gefitinib sensitivity.
Author: Nakata, Susumu|Tanaka, Harunari|Ito, Yuichi|Hara, Masayasu|Fujita, Mitsugu|Kondo, Eisaku|Kanemitsu, Yukihide|Yatabe, Yasushi|Nakanishi, Hayao
PMID: 25017791
Journal: Biochem Cell Biol. 2014 Aug;92(4):305-15.
Title: Involvement of ERK1/2, p38 MAPK, and PI3K/Akt signaling pathways in the regulation of cell cycle progression by PTHrP in colon adenocarcinoma cells.
Author: Calvo, Natalia|Martin, Maria Julia|de Boland, Ana Russo|Gentili, Claudia
PMID: 25051885
Journal: Mol Carcinog. 2015 Oct;54(10):1070-85.
Title: Piperine, an alkaloid from black pepper, inhibits growth of human colon cancer cells via G1 arrest and apoptosis triggered by endoplasmic reticulum stress.
Author: Yaffe, Paul B|Power Coombs, Melanie R|Doucette, Carolyn D|Walsh, Mark|Hoskin, David W
PMID: 24819444
Journal: Genet Med. 2015 Feb;17(2):131-42.
Title: Whole-exome sequencing identifies rare pathogenic variants in new predisposition genes for familial colorectal cancer.
Author: Esteban-Jurado, Clara|Vila-Casadesus, Maria|Garre, Pilar|Lozano, Juan Jose|Pristoupilova, Anna|Beltran, Sergi|Munoz, Jenifer|Ocana, Teresa|Balaguer, Francesc|Lopez-Ceron, Maria|Cuatrecasas, Miriam|Franch-Exposito, Sebastia|Pique, Josep M|Castells, Antoni|
PMID: 25058500
Journal: Cancer Chemother Pharmacol. 2015 Feb;75(2):411-20.
Title: Cks1 proteasomal degradation is induced by inhibiting Hsp90-mediated chaperoning in cancer cells.
Author: Khattar, Vinayak|Fried, Joshua|Xu, Bo|Thottassery, Jaideep V
PMID: 25544127
Journal: RNA Biol. 2015;12(3):276-89.
Title: microRNA-200b and microRNA-200c promote colorectal cancer cell proliferation via targeting the reversion-inducing cysteine-rich protein with Kazal motifs.
Author: Pan, Yi|Liang, Hongwei|Chen, Weixu|Zhang, Hongjie|Wang, Nan|Wang, Feng|Zhang, Suyang|Liu, Yanqing|Zhao, Chihao|Yan, Xin|Zhang, Junfeng|Zhang, Chen-Yu|Gu, Hongwei|Zen, Ke|Chen, Xi
PMID: 25826661
Journal: Sci Rep. 2015 Jun 9;5:11187.
Title: Folic acid inhibits COLO-205 colon cancer cell proliferation through activating the FRalpha/c-SRC/ERK1/2/NFkappaB/TP53 pathway: in vitro and in vivo studies.
Author: Kuo, Chun-Ting|Chang, Chieh|Lee, Wen-Sen
PMID: 26056802
Journal: J Gastrointestin Liver Dis. 2015 Jun;24(2):225-34.
Title: The role of Skp2 and its substrate CDKN1B (p27) in colorectal cancer.
Author: Bochis, Ovidiu V|Irimie, Alexandru|Pichler, Martin|Berindan-Neagoe, Ioana
PMID: 26114183
Journal: Int J Mol Sci. 2015 Jun 29;16(7):14655-68.
Title: Echinacoside Induces Apoptosis in Human SW480 Colorectal Cancer Cells by Induction of Oxidative DNA Damages.
Author: Dong, Liwei|Yu, Debin|Wu, Nuoting|Wang, Hongge|Niu, Jiajing|Wang, Ye|Zou, Zhihua
PMID: 26132569
Journal: Cancer Prev Res (Phila). 2015 Nov;8(11):1076-83.
Title: In vivo regulation of colonic cell proliferation, differentiation, apoptosis, and P27Kip1 by dietary fish oil and butyrate in rats.
Author: Hong, Mee Young|Turner, Nancy D|Murphy, Mary E|Carroll, Raymond J|Chapkin, Robert S|Lupton, Joanne R
PMID: 26323483
Journal: Sci Rep. 2015 Oct 16;5:15239.
Title: Pterostilbine, an active component of blueberries, sensitizes colon cancer cells to 5-fluorouracil cytotoxicity.
Author: Tolba, Mai F|Abdel-Rahman, Sherif Z
PMID: 26472352
Journal: Mol Carcinog. 2016 Feb;55(2):220-9.
Title: Rheb promotes cancer cell survival through p27Kip1-dependent activation of autophagy.
Author: Campos, Tania|Ziehe, Javiera|Palma, Mario|Escobar, David|Tapia, Julio C|Pincheira, Roxana|Castro, Ariel F
PMID: 25594310
Journal: Mol Carcinog. 2016 May;55(5):671-87.
Title: Cathepsin B promotes colorectal tumorigenesis, cell invasion, and metastasis.
Author: Bian, Benjamin|Mongrain, Sebastien|Cagnol, Sebastien|Langlois, Marie-Josee|Boulanger, Jim|Bernatchez, Gerald|Carrier, Julie C|Boudreau, Francois|Rivard, Nathalie
PMID: 25808857
Journal: Hum Exp Toxicol. 2016 May;35(5):526-43.
Title: Treatment with cucurbitacin B alone and in combination with gefitinib induces cell cycle inhibition and apoptosis via EGFR and JAK/STAT pathway in human colorectal cancer cell lines.
Author: Yar Saglam, A S|Alp, E|Elmazoglu, Z|Menevse, S
PMID: 26183715
Journal: Oncotarget. 2016 Jan 26;7(4):4542-58.
Title: The B56gamma3 regulatory subunit-containing protein phosphatase 2A outcompetes Akt to regulate p27KIP1 subcellular localization by selectively dephosphorylating phospho-Thr157 of p27KIP1.
Author: Lai, Tai-Yu|Yen, Chia-Jui|Tsai, Hung-Wen|Yang, Yu-San|Hong, Wei-Fu|Chiang, Chi-Wu
PMID: 26684356
Journal: Oncotarget. 2016 Jan 19;7(3):2878-88.
Title: TLE4 promotes colorectal cancer progression through activation of JNK/c-Jun signaling pathway.
Author: Wang, Shu-Yang|Gao, Ke|Deng, Dan-Ling|Cai, Juan-Juan|Xiao, Zhi-Yuan|He, Liu-Qing|Jiao, Hong-Li|Ye, Ya-Ping|Yang, Run-Wei|Li, Ting-Ting|Liang, Li|Liao, Wen-Ting|Ding, Yan-Qing
PMID: 26701208
Journal: PLoS One. 2016 Feb 9;11(2):e0148775.
Title: Flavokawain C Inhibits Cell Cycle and Promotes Apoptosis, Associated with Endoplasmic Reticulum Stress and Regulation of MAPKs and Akt Signaling Pathways in HCT 116 Human Colon Carcinoma Cells.
Author: Phang, Chung-Weng|Karsani, Saiful Anuar|Sethi, Gautam|Abd Malek, Sri Nurestri
PMID: 26859847
Journal: Int J Mol Sci. 2016 Apr 14;17(4):558.
Title: Induction of ROS Overload by Alantolactone Prompts Oxidative DNA Damage and Apoptosis in Colorectal Cancer Cells.
Author: Ding, Yushuang|Wang, Hongge|Niu, Jiajing|Luo, Manyu|Gou, Yangmei|Miao, Lining|Zou, Zhihua|Cheng, Ying
PMID: 27089328
Journal: Molecules. 2016 Jul 19;21(7). pii: molecules21070934.
Title: Protocatechualdehyde Induces S-Phase Arrest and Apoptosis by Stimulating the p27(KIP1)-Cyclin A/D1-CDK2 and Mitochondrial Apoptotic Pathways in HT-29 Cells.
Author: Zhong, Shi|Li, You-Gui|Ji, Dong-Feng|Lin, Tian-Bao|Lv, Zhi-Qiang
PMID: 27447597
Journal: J Exp Clin Cancer Res. 2016 Sep 27;35(1):152.
Title: TLE3 represses colorectal cancer proliferation by inhibiting MAPK and AKT signaling pathways.
Author: Yang, Run-Wei|Zeng, Ying-Yue|Wei, Wen-Ting|Cui, Yan-Mei|Sun, Hui-Ying|Cai, Yue-Long|Nian, Xin-Xin|Hu, Yun-Teng|Quan, Yu-Ping|Jiang, Sheng-Lu|Wang, Meng|Zhao, Ya-Li|Qiu, Jun-Feng|Li, Ming-Xuan|Zhang, Jia-Huan|He, Mei-Rong|Liang, Li|Ding, Yan-Qing|Liao, Wen
PMID: 27669982
Journal: BMC Complement Altern Med. 2016 Oct 1;16(1):384.
Title: Methylferulate from Tamarix aucheriana inhibits growth and enhances chemosensitivity of human colorectal cancer cells: possible mechanism of action.
Author: Abaza, Mohamed Salah I|Afzal, Mohammad|Al-Attiyah, Raja'a J|Guleri, Radhika
PMID: 27716288
Journal: Eur Rev Med Pharmacol Sci. 2016 Dec;20(23):4874-4879.
Title: Analysis of expression of cyclin E, p27kip1 and Ki67 protein in colorectal cancer tissues and its value for diagnosis, treatment and prognosis of disease.
Author: Li, W|Zhang, G|Wang, H-L|Wang, L
PMID: 27981549
Journal: Environ Toxicol. 2017 Aug;32(8):2041-2052.
Title: Casticin induced apoptotic cell death and altered associated gene expression in human colon cancer colo 205 cells.
Author: Shang, Hung-Sheng|Liu, Jia-You|Lu, Hsu-Feng|Chiang, Han-Sun|Lin, Chia-Hain|Chen, Ann|Lin, Yuh-Feng|Chung, Jing-Gung
PMID: 27862857
Journal: Nucleic Acids Res. 2017 May 19;45(9):5086-5099.
Title: p27Kip1, PCAF and PAX5 cooperate in the transcriptional regulation of specific target genes.
Author: Perearnau, Anna|Orlando, Serena|Islam, Abul B M M K|Gallastegui, Edurne|Martinez, Jonatan|Jordan, Albert|Bigas, Anna|Aligue, Rosa|Pujol, Maria Jesus|Bachs, Oriol
PMID: 28158851
Journal: PLoS One. 2017 Feb 14;12(2):e0169959.
Title: CacyBP/SIP promotes the proliferation of colon cancer cells.
Author: Zhai, Huihong|Shi, Yongquan|Chen, Xiong|Wang, Jun|Lu, Yuanyuan|Zhang, Faming|Liu, Zhengxiong|Lei, Ting|Fan, Daiming
PMID: 28196083
Journal: Gastroenterol Res Pract. 2017;2017:2808235.
Title: Immunohistochemical Markers as Predictors of Histopathologic Response and Prognosis in Rectal Cancer Treated with Preoperative Adjuvant Therapy: State of the Art.
Author: Del Gobbo, Alessandro|Ferrero, Stefano
PMID: 28326100
Journal: Mar Drugs. 2017 May 30;15(6). pii: md15060154.
Title: Induction of p53-Independent Apoptosis and G1 Cell Cycle Arrest by Fucoidan in HCT116 Human Colorectal Carcinoma Cells.
Author: Park, Hye Young|Park, Shin-Hyung|Jeong, Jin-Woo|Yoon, Dahye|Han, Min Ho|Lee, Dae-Sung|Choi, Grace|Yim, Mi-Jin|Lee, Jeong Min|Kim, Do-Hyung|Kim, Gi-Young|Choi, Il-Whan|Kim, Suhkmann|Kim, Heui-Soo|Cha, Hee-Jae|Choi, Yung Hyun
PMID: 28555064
Journal: Adv Med Biol. 2017 1st Quarter;118:83-122.
Title: Haploinsufficient tumor suppressor genes.
Author: Inoue, Kazushi|Fry, Elizabeth A
PMID: 28680740
Journal: Sci Rep. 2017 Aug 8;7(1):7599.
Title: Anti-colon cancer effect of caffeic acid p-nitro-phenethyl ester in vitro and in vivo and detection of its metabolites.
Author: Tang, Hao|Yao, Xiaofang|Yao, Cong|Zhao, Xiaoyan|Zuo, Hua|Li, Zhubo
PMID: 28790461
Journal: Int J Oncol. 2017 Nov;51(5):1611-1620.
Title: Combination of FGFR4 inhibitor Blu9931 and 5-fluorouracil effects on the biological characteristics of colorectal cancer cells.
Author: Jiang, Dongbao|Li, Jingjing|Li, Jie|Wang, Min|Han, Chao|Wang, Xinru|Zhao, Chunlin|Ye, Yanwei
PMID: 29048661
Journal: Oncol Lett. 2017 Nov;14(5):6203-6209.
Title: JAB1-STAT3 activation loop is associated with recurrence following 5-fluorouracil-based adjuvant chemotherapy in human colorectal cancer.
Author: Kugimiya, Naruji|Nishimoto, Arata|Hosoyama, Tohru|Ueno, Koji|Takemoto, Yoshihiro|Harada, Eijiro|Enoki, Tadahiko|Hamano, Kimikazu
PMID: 29113268
Journal: Carcinogenesis. 2018 Jan 12;39(1):36-46.
Title: Potent suppression of both spontaneous and carcinogen-induced colitis-associated colorectal cancer in mice by dietary celastrol supplementation.
Author: Barker, Emily C|Kim, Byung-Gyu|Yoon, Ji Hee|Tochtrop, Gregory P|Letterio, John J|Choi, Sung Hee
PMID: 29069290
Journal: Oncogene. 2018 Jul 4. pii: 10.1038/s41388-018-0363-4.
Title: Alternative NF-kappaB signaling promotes colorectal tumorigenesis through transcriptionally upregulating Bcl-3.
Author: Tao, Yu|Liu, Zhanjie|Hou, Yingyong|Wang, Shouli|Liu, Sanhong|Jiang, Yuhang|Tan, Dan|Ge, Qiulin|Li, Cuifeng|Hu, Yiming|Liu, Zhi|Chen, Xi|Wang, Qi|Wang, Mingliang|Zhang, Xiaoren
PMID: 29973688
Journal: J Exp Clin Cancer Res. 2018 Aug 7;37(1):187.
Title: PCBP1 depletion promotes tumorigenesis through attenuation of p27(Kip1) mRNA stability and translation.
Author: Shi, Hongshun|Li, Hui|Yuan, Ronghua|Guan, Wen|Zhang, Xiaomei|Zhang, Shaoyang|Zhang, Wenliang|Tong, Fang|Li, Li|Song, Zhihong|Wang, Changwei|Yang, Shulan|Wang, Haihe
PMID: 30086790
Journal: Biomed Pharmacother. 2018 Oct;106:1135-1143.
Title: Exosome-mediated miR-200b promotes colorectal cancer proliferation upon TGF-beta1 exposure.
Author: Zhang, Zhen|Xing, Tongchao|Chen, Yanhui|Xiao, Jiangmei
PMID: 30119180
Journal: Surg Endosc. 2018 Aug 31. pii: 10.1007/s00464-018-6411-x.
Title: Colonic stent-induced mechanical compression may suppress cancer cell proliferation in malignant large bowel obstruction.
Author: Matsuda, Akihisa|Miyashita, Masao|Matsumoto, Satoshi|Sakurazawa, Nobuyuki|Kawano, Youichi|Yamahatsu, Kazuya|Sekiguchi, Kumiko|Yamada, Marina|Hatori, Tsutomu|Yoshida, Hiroshi
PMID: 30171397
Journal: Oncol Lett. 2018 Oct;16(4):4640-4648.
Title: Total ginsenosides of Chinese ginseng induces cell cycle arrest and apoptosis in colorectal carcinoma HT-29 cells.
Author: Li, Ting|Sun, Wan|Dong, Xiaoqiao|Yu, Wenhua|Cai, Jianyong|Yuan, Qiang|Shan, Letian|Efferth, Thomas
PMID: 30197678
Journal: Oncol Lett. 2018 Oct;16(4):5275-5281.
Title: Increased EZH2 expression during the adenoma-carcinoma sequence in colorectal cancer.
Author: Ohuchi, Mayuko|Sakamoto, Yasuo|Tokunaga, Ryuma|Kiyozumi, Yuki|Nakamura, Kenichi|Izumi, Daisuke|Kosumi, Keisuke|Harada, Kazuto|Kurashige, Junji|Iwatsuki, Masaaki|Baba, Yoshifumi|Miyamoto, Yuji|Yoshida, Naoya|Shono, Takashi|Naoe, Hideaki|Sasaki, Yutaka|Baba
PMID: 30214616
Journal: Med Chem Res. 2018;27(9):2150-2159.
Title: Evaluation of the effect of 2-(2,4-dihydroxyphenyl)-4H-benzofuro[3,2-d][1,3]thiazin-4-one on colon cells and its anticancer potential.
Author: Czerwonka, Arkadiusz|Lemieszek, Marta K|Karpinska, Monika|Matysiak, Joanna|Niewiadomy, Andrzej|Rzeski, Wojciech
PMID: 30220832