Primary Site >> Colorectal Cancer
Gene >> CDKN1B
| 1. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6380-5. | ||||||||||
| Title: | High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers. | ||||||||||
| Author: | Fredersdorf, S|Burns, J|Milne, A M|Packham, G|Fallis, L|Gillett, C E|Royds, J A|Peston, D|Hall, P A|Hanby, A M|Barnes, D M|Shousha, S|O'Hare, M J|Lu, X | ||||||||||
| PMID: | 9177226 | ||||||||||
| 2. | |||||||||||
| Journal: | Jpn J Cancer Res. 1997 Jul;88(7):625-9. | ||||||||||
| Title: | Reduced expression of cyclin-dependent kinase inhibitor p27Kip1 is associated with advanced stage and invasiveness of gastric carcinomas. | ||||||||||
| Author: | Yasui, W|Kudo, Y|Semba, S|Yokozaki, H|Tahara, E | ||||||||||
| PMID: | 9310133 | ||||||||||
| 3. | |||||||||||
| Journal: | Cancer Res. 1997 Nov 1;57(21):4838-48. | ||||||||||
| Title: | Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase. | ||||||||||
| Author: | Moyer, J D|Barbacci, E G|Iwata, K K|Arnold, L|Boman, B|Cunningham, A|DiOrio, C|Doty, J|Morin, M J|Moyer, M P|Neveu, M|Pollack, V A|Pustilnik, L R|Reynolds, M M|Sloan, D|Theleman, A|Miller, P | ||||||||||
| PMID: | 9354447 | ||||||||||
| 4. | |||||||||||
| Journal: | Clin Cancer Res. 1997 Dec;3(12 Pt 2):2696-702. | ||||||||||
| Title: | Disorders in cell circuitry associated with multistage carcinogenesis: exploitable targets for cancer prevention and therapy. | ||||||||||
| Author: | Weinstein, I B|Begemann, M|Zhou, P|Han, E K|Sgambato, A|Doki, Y|Arber, N|Ciaparrone, M|Yamamoto, H | ||||||||||
| PMID: | 10068276 | ||||||||||
| 5. | |||||||||||
| Journal: | Cancer Res. 1998 Jan 1;58(1):114-22. | ||||||||||
| Title: | Localization and expression of p27KIP1 in multistage colorectal carcinogenesis. | ||||||||||
| Author: | Ciaparrone, M|Yamamoto, H|Yao, Y|Sgambato, A|Cattoretti, G|Tomita, N|Monden, T|Rotterdam, H|Weinstein, I B | ||||||||||
| PMID: | 9426067 | ||||||||||
| 6. | |||||||||||
| Journal: | Int J Oncol. 1998 Sep;13(3):611-7. | ||||||||||
| Title: | gamma-Linolenic acid blocks cell cycle progression by regulating phosphorylation of p27kip1 and p57kip2 and their interactions with other cycle regulators in cancer cells. | ||||||||||
| Author: | Jiang, W G|Bryce, R P|Horrobin, D F|Mansel, R E | ||||||||||
| PMID: | 9683802 | ||||||||||
| 7. | |||||||||||
| Journal: | Int J Cancer. 1998 Aug 31;77(5):796-802. | ||||||||||
| Title: | Contribution of the cyclin-dependent kinase inhibitor p27KIP1 to the confluence-dependent resistance of HT29 human colon carcinoma cells. | ||||||||||
| Author: | Dimanche-Boitrel, M T|Micheau, O|Hammann, A|Haugg, M|Eymin, B|Chauffert, B|Solary, E | ||||||||||
| PMID: | 9688315 | ||||||||||
| 8. | |||||||||||
| Journal: | Cancer. 1998 Dec 15;83(12):2447-55. | ||||||||||
| Title: | Reduced expression of cyclin-dependent kinase inhibitor p27Kip1 is an indicator of malignant behavior in oral squamous cell carcinoma. | ||||||||||
| Author: | Kudo, Y|Takata, T|Yasui, W|Ogawa, I|Miyauchi, M|Takekoshi, T|Tahara, E|Nikai, H | ||||||||||
| PMID: | 9874448 | ||||||||||
| 9. | |||||||||||
| Journal: | Oncogene. 1999 Jan 7;18(1):103-15. | ||||||||||
| Title: | Comparative effects of overexpression of p27Kip1 and p21Cip1/Waf1 on growth and differentiation in human colon carcinoma cells. | ||||||||||
| Author: | Yamamoto, H|Soh, J W|Shirin, H|Xing, W Q|Lim, J T|Yao, Y|Slosberg, E|Tomita, N|Schieren, I|Weinstein, I B | ||||||||||
| PMID: | 9926925 | ||||||||||
| 10. | |||||||||||
| Journal: | Ann Surg Oncol. 1999 Jan-Feb;6(1):19-25. | ||||||||||
| Title: | Absence of the cell cycle inhibitor p27Kip1 protein predicts poor outcome in patients with stage I-III colorectal cancer. | ||||||||||
| Author: | Belluco, C|Esposito, G|Bertorelle, R|Del Mistro, A|Fassina, A|Vieceli, G|Chieco-Bianchi, L|Nitti, D|Lise, M | ||||||||||
| PMID: | 10030411 | ||||||||||
| 11. | |||||||||||
| Journal: | Mol Cell Biol. 1999 May;19(5):3916-28. | ||||||||||
| Title: | Induction of p21(WAF1/CIP1) and inhibition of Cdk2 mediated by the tumor suppressor p16(INK4a). | ||||||||||
| Author: | Mitra, J|Dai, C Y|Somasundaram, K|El-Deiry, W S|Satyamoorthy, K|Herlyn, M|Enders, G H | ||||||||||
| PMID: | 10207115 | ||||||||||
| 12. | |||||||||||
| Journal: | Clin Cancer Res. 1999 May;5(5):1057-62. | ||||||||||
| Title: | Paradoxical correlations of cyclin-dependent kinase inhibitors p21waf1/cip1 and p27kip1 in metastatic colorectal carcinoma. | ||||||||||
| Author: | Cheng, J D|Werness, B A|Babb, J S|Meropol, N J | ||||||||||
| PMID: | 10353738 | ||||||||||
| 13. | |||||||||||
| Journal: | Cancer Res. 1999 Jul 1;59(13):3245-50. | ||||||||||
| Title: | Loss of P27Kip1 expression correlates with tumor grade and with reduced disease-free survival in primary superficial bladder cancers. | ||||||||||
| Author: | Sgambato, A|Migaldi, M|Faraglia, B|Garagnani, L|Romano, G|De Gaetani, C|Ferrari, P|Capelli, G|Trentini, G P|Cittadini, A | ||||||||||
| PMID: | 10397272 | ||||||||||
| 14. | |||||||||||
| Journal: | J Pathol. 1999 May;188(1):18-23. | ||||||||||
| Title: | Prognostic significance of p27(Kip1) expression in colorectal cancer: a clinico-pathological characterization. | ||||||||||
| Author: | Palmqvist, R|Stenling, R|Oberg, A|Landberg, G | ||||||||||
| PMID: | 10398135 | ||||||||||
| 15. | |||||||||||
| Journal: | Mod Pathol. 1999 Aug;12(8):751-5. | ||||||||||
| Title: | Levels of expression of p27KIP1 protein in human prostate and prostate cancer: an immunohistochemical analysis. | ||||||||||
| Author: | Erdamar, S|Yang, G|Harper, J W|Lu, X|Kattan, M W|Thompson, T C|Wheeler, T M | ||||||||||
| PMID: | 10463475 | ||||||||||
| 16. | |||||||||||
| Journal: | Mol Carcinog. 1999 Nov;26(3):172-9. | ||||||||||
| Title: | Reduced expression and altered subcellular localization of the cyclin-dependent kinase inhibitor p27(Kip1) in human colon cancer. | ||||||||||
| Author: | Sgambato, A|Ratto, C|Faraglia, B|Merico, M|Ardito, R|Schinzari, G|Romano, G|Cittadini, A R | ||||||||||
| PMID: | 10559792 | ||||||||||
| 17. | |||||||||||
| Journal: | Crit Rev Oncog. 1999;10(4):303-60. | ||||||||||
| Title: | The role for transforming growth factor-beta (TGF-beta) in human cancer. | ||||||||||
| Author: | Gold, L I | ||||||||||
| PMID: | 10654929 | ||||||||||
| 18. | |||||||||||
| Journal: | Jpn J Cancer Res. 1999 Dec;90(12):1364-72. | ||||||||||
| Title: | G1-checkpoint function including a cyclin-dependent kinase 2 regulatory pathway as potential determinant of 7-hydroxystaurosporine (UCN-01)-induced apoptosis and G1-phase accumulation. | ||||||||||
| Author: | Akiyama, T|Sugiyama, K|Shimizu, M|Tamaoki, T|Akinaga, S | ||||||||||
| PMID: | 10665655 | ||||||||||
| 19. | |||||||||||
| Journal: | Pathobiology. 1999 Jul-Aug;67(4):174-9. | ||||||||||
| Title: | Expression of cell-cycle-regulating transcription factor E2F-1 in colorectal carcinomas. | ||||||||||
| Author: | Yasui, W|Fujimoto, J|Suzuki, T|Ono, S|Naka, K|Yokozaki, H|Tahara, E | ||||||||||
| PMID: | 10738178 | ||||||||||
| 20. | |||||||||||
| Journal: | Colorectal Dis. 1999 Nov;1(6):315-23. | ||||||||||
| Title: | p27(kipl) protein expression: an independent prognostic factor in rectal carcinoma stages I-III. | ||||||||||
| Author: | Pucciarelli|Esposito|Fassina|Alaggio|Masin|Toppan|Chieco-Bianchi|Lise | ||||||||||
| PMID: | 23574593 | ||||||||||
| 21. | |||||||||||
| Journal: | Carcinogenesis. 2000 May;21(5):857-64. | ||||||||||
| Title: | Disorders in cell circuitry during multistage carcinogenesis: the role of homeostasis. | ||||||||||
| Author: | Weinstein, I B | ||||||||||
| PMID: | 10783304 | ||||||||||
| 22. | |||||||||||
| Journal: | Anticancer Res. 2000 Mar-Apr;20(2A):779-84. | ||||||||||
| Title: | Induction of apoptosis in human gastric cancer by sodium butyrate. | ||||||||||
| Author: | Litvak, D A|Hwang, K O|Evers, B M|Townsend, C M Jr | ||||||||||
| PMID: | 10810354 | ||||||||||
| 23. | |||||||||||
| Journal: | Anticancer Res. 2000 Mar-Apr;20(2A):849-52. | ||||||||||
| Title: | P27KiP1 overexpression inhibits the growth and doxorubicin sensitivity of HT29 human colon cancer cells in vivo. | ||||||||||
| Author: | Dimanche-Boitrel, M T|Micheau, O|France, D|Hammann, A|Duchamp, O|Genne, P|Solary, E | ||||||||||
| PMID: | 10810365 | ||||||||||
| 24. | |||||||||||
| Journal: | J Surg Res. 2000 Jul;92(1):78-84. | ||||||||||
| Title: | p27(kip1) expression in rectal cancer correlates with disease-free survival. | ||||||||||
| Author: | Gunther, K|Jung, A|Volker, U|Meyer, M|Brabletz, T|Matzel, K E|Reymond, M A|Kirchner, T|Hohenberger, W | ||||||||||
| PMID: | 10864486 | ||||||||||
| 25. | |||||||||||
| Journal: | Clin Cancer Res. 2000 Jul;6(7):2881-90. | ||||||||||
| Title: | Augmentation of antitumor activity of 5-fluorouracil by interferon alpha is associated with up-regulation of p27Kip1 in human hepatocellular carcinoma cells. | ||||||||||
| Author: | Eguchi, H|Nagano, H|Yamamoto, H|Miyamoto, A|Kondo, M|Dono, K|Nakamori, S|Umeshita, K|Sakon, M|Monden, M | ||||||||||
| PMID: | 10914738 | ||||||||||
| 26. | |||||||||||
| Journal: | Clin Cancer Res. 2000 Jul;6(7):2951-8. | ||||||||||
| Title: | Changes in E2F binding after phenylbutyrate-induced differentiation of Caco-2 colon cancer cells. | ||||||||||
| Author: | Wang, Q M|Feinman, R|Kashanchi, F|Houghton, J M|Studzinski, G P|Harrison, L E | ||||||||||
| PMID: | 10914745 | ||||||||||
| 27. | |||||||||||
| Journal: | Urology. 2000 Oct 1;56(4):689-95. | ||||||||||
| Title: | Cyclin-dependent kinase inhibitor P27(KIP1) is expressed preferentially in early stages of urothelial carcinoma. | ||||||||||
| Author: | Franke, K H|Miklosi, M|Goebell, P|Clasen, S|Steinhoff, C|Anastasiadis, A G|Gerharz, C|Schulz, W A | ||||||||||
| PMID: | 11018640 | ||||||||||
| 28. | |||||||||||
| Journal: | Int J Biochem Cell Biol. 2000 Sep;32(9):957-65. | ||||||||||
| Title: | Lovastatin and simvastatin are modulators of the proteasome. | ||||||||||
| Author: | Wojcik, C|Bury, M|Stoklosa, T|Giermasz, A|Feleszko, W|Mlynarczuk, I|Pleban, E|Basak, G|Omura, S|Jakobisiak, M | ||||||||||
| PMID: | 11084375 | ||||||||||
| 29. | |||||||||||
| Journal: | Endocrinology. 2000 Nov;141(11):3931-9. | ||||||||||
| Title: | A vitamin D3 analog induces a G1-phase arrest in CaCo-2 cells by inhibiting cdk2 and cdk6: roles of cyclin E, p21Waf1, and p27Kip1. | ||||||||||
| Author: | Scaglione-Sewell, B A|Bissonnette, M|Skarosi, S|Abraham, C|Brasitus, T A | ||||||||||
| PMID: | 11089522 | ||||||||||
| 30. | |||||||||||
| Journal: | Biomarkers. 2000;5(3):225-34. | ||||||||||
| Title: | Expression of p27(Kip1) and bcl-2, cigarette smoking, and colorectal cancer risk. | ||||||||||
| Author: | Ishibe, N|Freedman, A N|Michalek, A M|Iacobuziodonahue, C|Mettlin, C J|Petrelli, N J|Asirwatham, J E|Hamilton, S R | ||||||||||
| PMID: | 23889224 | ||||||||||
| 31. | |||||||||||
| Journal: | Oncogene. 2001 Apr 5;20(15):1913-22. | ||||||||||
| Title: | Fibroblast growth factor and insulin-like growth factor differentially modulate the apoptosis and G1 arrest induced by anti-epidermal growth factor receptor monoclonal antibody. | ||||||||||
| Author: | Liu, B|Fang, M|Lu, Y|Mendelsohn, J|Fan, Z | ||||||||||
| PMID: | 11313939 | ||||||||||
| 32. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2001 Apr 27;283(1):80-5. | ||||||||||
| Title: | 1,25-Dihydroxycholecalciferol enhances butyrate-induced p21(Waf1/Cip1) expression. | ||||||||||
| Author: | Gaschott, T|Wachtershauser, A|Steinhilber, D|Stein, J | ||||||||||
| PMID: | 11322770 | ||||||||||
| 33. | |||||||||||
| Journal: | Cancer. 2001 May 1;91(9):1745-51. | ||||||||||
| Title: | Inverse relation between levels of p27(Kip1) and of its ubiquitin ligase subunit Skp2 in colorectal carcinomas. | ||||||||||
| Author: | Hershko, D|Bornstein, G|Ben-Izhak, O|Carrano, A|Pagano, M|Krausz, M M|Hershko, A | ||||||||||
| PMID: | 11335900 | ||||||||||
| 34. | |||||||||||
| Journal: | Endocr Relat Cancer. 2001 Mar;8(1):3-9. | ||||||||||
| Title: | The epidermal growth factor receptor as a target for cancer therapy. | ||||||||||
| Author: | Mendelsohn, J | ||||||||||
| PMID: | 11350723 | ||||||||||
| 35. | |||||||||||
| Journal: | Ann Surg Oncol. 2001 May;8(4):311-8. | ||||||||||
| Title: | P27kip1 expression is associated with tumor response to preoperative chemoradiotherapy in rectal cancer. | ||||||||||
| Author: | Esposito, G|Pucciarelli, S|Alaggio, R|Giacomelli, L|Marchiori, E|Iaderosa, G A|Friso, M L|Toppan, P|Chieco-Bianchi, L|Lise, M | ||||||||||
| PMID: | 11352304 | ||||||||||
| 36. | |||||||||||
| Journal: | J Cell Biol. 2001 Aug 6;154(3):573-84. | ||||||||||
| Title: | Expression of alpha-catenin in alpha-catenin-deficient cells increases resistance to sphingosine-induced apoptosis. | ||||||||||
| Author: | Matsubara, S|Ozawa, M | ||||||||||
| PMID: | 11489917 | ||||||||||
| 37. | |||||||||||
| Journal: | FASEB J. 2001 Dec;15(14):2742-4. Epub 2001 Oct 15. | ||||||||||
| Title: | COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib. | ||||||||||
| Author: | Grosch, S|Tegeder, I|Niederberger, E|Brautigam, L|Geisslinger, G | ||||||||||
| PMID: | 11606477 | ||||||||||
| 38. | |||||||||||
| Journal: | Oncol Rep. 2002 Jan-Feb;9(1):29-33. | ||||||||||
| Title: | 5-FU improves p27-related poor prognosis in patients with Astler-Coller B2-C colorectal carcinoma. | ||||||||||
| Author: | Kobayashi, Minako|Shiraishi, Taizo|Tonouchi, Hitoshi|Miki, Chikao|Kusunoki, Masato | ||||||||||
| PMID: | 11748451 | ||||||||||
| 39. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2002 Jan 11;290(1):504-9. | ||||||||||
| Title: | ZK 156718, a low calcemic, antiproliferative, and prodifferentiating vitamin D analog. | ||||||||||
| Author: | Gaschott, Tanja|Steinmeyer, Andreas|Steinhilber, Dieter|Stein, Jurgen | ||||||||||
| PMID: | 11779200 | ||||||||||
| 40. | |||||||||||
| Journal: | J Nutr. 2002 Feb;132(2):298-302. | ||||||||||
| Title: | Piceatannol, a natural analog of resveratrol, inhibits progression through the S phase of the cell cycle in colorectal cancer cell lines. | ||||||||||
| Author: | Wolter, Freya|Clausnitzer, Antje|Akoglu, Bora|Stein, Jurgen | ||||||||||
| PMID: | 11823594 | ||||||||||
| 41. | |||||||||||
| Journal: | Mol Cell Biol. 2002 Apr;22(7):2025-36. | ||||||||||
| Title: | Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors. | ||||||||||
| Author: | Kops, Geert J P L|Medema, Rene H|Glassford, Janet|Essers, Marieke A G|Dijkers, Pascale F|Coffer, Paul J|Lam, Eric W-F|Burgering, Boudewijn M T | ||||||||||
| PMID: | 11884591 | ||||||||||
| 42. | |||||||||||
| Journal: | Int J Cancer. 2002 Apr 10;98(5):665-73. | ||||||||||
| Title: | Insulin-like growth factor-I has a biphasic effect on colon carcinoma cells through transient inactivation of forkhead1, initially mitogenic, then mediating growth arrest and differentiation. | ||||||||||
| Author: | Ewton, Daina Z|Kansra, Sanjay|Lim, Seunghwan|Friedman, Eileen | ||||||||||
| PMID: | 11920634 | ||||||||||
| 43. | |||||||||||
| Journal: | Toxicol Appl Pharmacol. 2002 Apr 1;180(1):22-35. | ||||||||||
| Title: | Antitumor effects of miconazole on human colon carcinoma xenografts in nude mice through induction of apoptosis and G0/G1 cell cycle arrest. | ||||||||||
| Author: | Wu, Chih-Hsiung|Jeng, Jiiang-Huei|Wang, Ying-Jan|Tseng, Chia-Jen|Liang, Yu-Chih|Chen, Chien-Ho|Lee, Horng-Mo|Lin, Jen-Kun|Lin, Chien-Huang|Lin, Shyr-Yi|Li, Chung-Pei|Ho, Yuan-Soon | ||||||||||
| PMID: | 11922774 | ||||||||||
| 44. | |||||||||||
| Journal: | Int J Colorectal Dis. 2002 Jan;17(1):11-9. | ||||||||||
| Title: | p21, p27, cyclin D1, and p53 in rectal cancer: immunohistology with prognostic significance? | ||||||||||
| Author: | Schwandner, O|Bruch, H P|Broll, R | ||||||||||
| PMID: | 12018448 | ||||||||||
| 45. | |||||||||||
| Journal: | Am J Clin Pathol. 2002 Jun;117(6):908-15. | ||||||||||
| Title: | High apoptotic activity and low epithelial cell proliferation with underexpression of p21(WAF1/CIP1) and p27Kip1 of mucinous carcinomas of the colorectum: comparison with well-differentiated type. | ||||||||||
| Author: | Akino, Fumiyuki|Mitomi, Hiroyuki|Nakamura, Takatoshi|Ohtani, Yoshimasa|Ichinoe, Masaaki|Okayasu, Isao | ||||||||||
| PMID: | 12047142 | ||||||||||
| 46. | |||||||||||
| Journal: | Cancer Cell. 2002 May;1(4):355-68. | ||||||||||
| Title: | Pathway-specific tumor suppression. Reduction of p27 accelerates gastrointestinal tumorigenesis in Apc mutant mice, but not in Smad3 mutant mice. | ||||||||||
| Author: | Philipp-Staheli, Jeannette|Kim, Kyung-Hoon|Payne, Shannon R|Gurley, Kay E|Liggitt, Denny|Longton, Gary|Kemp, Christopher J | ||||||||||
| PMID: | 12086850 | ||||||||||
| 47. | |||||||||||
| Journal: | J Nutr. 2002 Jul;132(7):2082-6. | ||||||||||
| Title: | Resveratrol enhances the differentiation induced by butyrate in caco-2 colon cancer cells. | ||||||||||
| Author: | Wolter, Freya|Stein, Jurgen | ||||||||||
| PMID: | 12097697 | ||||||||||
| 48. | |||||||||||
| Journal: | Cancer Res. 2002 Jul 15;62(14):3997-4006. | ||||||||||
| Title: | Growth inhibition of human hepatoma cells by acyclic retinoid is associated with induction of p21(CIP1) and inhibition of expression of cyclin D1. | ||||||||||
| Author: | Suzui, Masumi|Masuda, Muneyuki|Lim, Jin T E|Albanese, Chris|Pestell, Richard G|Weinstein, I Bernard | ||||||||||
| PMID: | 12124333 | ||||||||||
| 49. | |||||||||||
| Journal: | J Cell Biochem. 2002;87(2):147-59. | ||||||||||
| Title: | Ketoconazole potentiates terfenadine-induced apoptosis in human Hep G2 cells through inhibition of cytochrome p450 3A4 activity. | ||||||||||
| Author: | Wang, Ying-Jan|Yu, Cheng-Fei|Chen, Li-Ching|Chen, Chien-Ho|Lin, Jen-Kun|Liang, Yu-Chih|Lin, Chien-Huang|Lin, Shyr-Yi|Chen, Chin-Fa|Ho, Yuan-Soon | ||||||||||
| PMID: | 12244568 | ||||||||||
| 50. | |||||||||||
| Journal: | Hum Pathol. 2002 Oct;33(10):1006-15. | ||||||||||
| Title: | Cyclin A correlates with carcinogenesis and metastasis, and p27(kip1) correlates with lymphatic invasion, in colorectal neoplasms. | ||||||||||
| Author: | Li, Jia-Qing|Miki, Hiroshi|Wu, Fei|Saoo, Kousuke|Nishioka, Mikio|Ohmori, Masaki|Imaida, Katsumi | ||||||||||
| PMID: | 12395374 | ||||||||||
| 51. | |||||||||||
| Journal: | Eur Surg Res. 2002 Nov-Dec;34(6):389-96. | ||||||||||
| Title: | Prognostic significance of p21 and p27 protein, apoptosis, clinical and histologic factors in rectal cancer without lymph node metastases. | ||||||||||
| Author: | Schwandner, O|Bruch, H-P|Broll, R | ||||||||||
| PMID: | 12403937 | ||||||||||
| 52. | |||||||||||
| Journal: | Int J Cancer. 2003 Jan 1;103(1):21-8. | ||||||||||
| Title: | Rapid turnover of cell-cycle regulators found in Mirk/dyrk1B transfectants. | ||||||||||
| Author: | Ewton, Daina Z|Lee, Kangmoon|Deng, Xiaobing|Lim, Seunghwan|Friedman, Eileen | ||||||||||
| PMID: | 12455049 | ||||||||||
| 53. | |||||||||||
| Journal: | Cancer Cell. 2003 Mar;3(3):233-45. | ||||||||||
| Title: | Proliferation of cancer cells despite CDK2 inhibition. | ||||||||||
| Author: | Tetsu, Osamu|McCormick, Frank | ||||||||||
| PMID: | 12676582 | ||||||||||
| 54. | |||||||||||
| Journal: | J Gene Med. 2003 Apr;5(4):287-99. | ||||||||||
| Title: | 5-Fluorouracil efficiently enhanced apoptosis induced by adenovirus-mediated transfer of caspase-8 in DLD-1 colon cancer cells. | ||||||||||
| Author: | Uchida, Hiroaki|Shinoura, Nobusada|Kitayama, Joji|Watanabe, Toshiaki|Nagawa, Hirokazu|Hamada, Hirofumi | ||||||||||
| PMID: | 12692863 | ||||||||||
| 55. | |||||||||||
| Journal: | Oncol Rep. 2003 Jul-Aug;10(4):827-31. | ||||||||||
| Title: | Prognostic significance of p27/kip1 and apoptosis in patients with colorectal carcinoma. | ||||||||||
| Author: | Noguchi, Tsuyoshi|Kikuchi, Ryuichi|Ono, Kiyoshi|Takeno, Shinsuke|Moriyama, Hatsuo|Uchida, Yuzo | ||||||||||
| PMID: | 12792730 | ||||||||||
| 56. | |||||||||||
| Journal: | Int J Cancer. 2003 Aug 10;106(1):125-37. | ||||||||||
| Title: | In vitro and in vivo studies of the anticancer action of terbinafine in human cancer cell lines: G0/G1 p53-associated cell cycle arrest. | ||||||||||
| Author: | Lee, Wen-Sen|Chen, Rong-Jane|Wang, Ying-Jan|Tseng, How|Jeng, Jiiang-Huei|Lin, Shyr-Yi|Liang, Yu-Chih|Chen, Chien-Ho|Lin, Chien-Huang|Lin, Jen-Kun|Ho, Pei-Yin|Chu, Jan-Show|Ho, Wei-Lu|Chen, Li-Ching|Ho, Yuan-Soon | ||||||||||
| PMID: | 12794767 | ||||||||||
| 57. | |||||||||||
| Journal: | Clin Cancer Res. 2003 Jul;9(7):2457-64. | ||||||||||
| Title: | A pharmacodynamic study of the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in metastatic colorectal cancer patients. | ||||||||||
| Author: | Daneshmand, Manijeh|Parolin, Doris A E|Hirte, Holger W|Major, Pierre|Goss, Glenwood|Stewart, David|Batist, Gerald|Miller, Wilson H Jr|Matthews, Sarah|Seymour, Lesley|Lorimer, Ian A J | ||||||||||
| PMID: | 12855618 | ||||||||||
| 58. | |||||||||||
| Journal: | J Cancer Res Clin Oncol. 2003 Aug;129(8):449-55. | ||||||||||
| Title: | Different apoptotic activity and p21(WAF1/CIP1), but not p27(Kip1), expression in serrated adenomas as compared with traditional adenomas and hyperplastic polyps of the colorectum. | ||||||||||
| Author: | Mitomi, Hiroyuki|Sada, Miwa|Kobayashi, Kiyonori|Igarashi, Masahiro|Mori, Akio|Kanazawa, Hideki|Nishiyama, Yasuhiko|Ihara, Atsushi|Otani, Yoshimasa | ||||||||||
| PMID: | 12884030 | ||||||||||
| 59. | |||||||||||
| Journal: | J Surg Res. 2003 Aug;113(2):179-88. | ||||||||||
| Title: | P27 does not predict histopathological response to radiochemotherapy in rectal cancer. | ||||||||||
| Author: | Gunther, Klaus|Dimmler, Arno|Rodel, Franz|Reulbach, Udo|Merkel, Susanne|Bittorf, Birgit R|Matzel, Klaus E|Papadopoulos, Thomas|Hohenberger, Werner|Sauer, Rolf|Rodel, Claus | ||||||||||
| PMID: | 12957127 | ||||||||||
| 60. | |||||||||||
| Journal: | J Clin Oncol. 2003 Oct 1;21(19):3594-600. | ||||||||||
| Title: | High p27Kip1 expression predicts superior relapse-free and overall survival for premenopausal women with early-stage breast cancer receiving adjuvant treatment with tamoxifen plus goserelin. | ||||||||||
| Author: | Pohl, Gudrun|Rudas, Margaretha|Dietze, Otto|Lax, Sigurd|Markis, Eva|Pirker, Robert|Zielinski, Christoph C|Hausmaninger, Hubert|Kubista, Ernst|Samonigg, Hellmut|Jakesz, Raimund|Filipits, Martin | ||||||||||
| PMID: | 14512390 | ||||||||||
| 61. | |||||||||||
| Journal: | Dig Liver Dis. 2003 Aug;35(8):557-65. | ||||||||||
| Title: | Molecular mechanisms involved in the antiproliferative effect of two COX-2 inhibitors, nimesulide and NS-398, on colorectal cancer cell lines. | ||||||||||
| Author: | Buecher, B|Broquet, A|Bouancheau, D|Heymann, M F|Jany, A|Denis, M G|Bonnet, C|Galmiche, J P|Blottiere, H M | ||||||||||
| PMID: | 14567460 | ||||||||||
| 62. | |||||||||||
| Journal: | Oncogene. 2003 Nov 13;22(51):8271-82. | ||||||||||
| Title: | Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells. | ||||||||||
| Author: | Agarwal, Chapla|Singh, Rana P|Dhanalakshmi, Sivanandhan|Tyagi, Anil K|Tecklenburg, Marianne|Sclafani, Robert A|Agarwal, Rajesh | ||||||||||
| PMID: | 14614451 | ||||||||||
| 63. | |||||||||||
| Journal: | Nutr Cancer. 2003;46(2):186-96. | ||||||||||
| Title: | Anthocyanin-rich extract from Aronia meloncarpa E induces a cell cycle block in colon cancer but not normal colonic cells. | ||||||||||
| Author: | Malik, Minnie|Zhao, Cuiwei|Schoene, Norberta|Guisti, M Monica|Moyer, Mary P|Magnuson, Bernadene A | ||||||||||
| PMID: | 14690795 | ||||||||||
| 64. | |||||||||||
| Journal: | Biochem Pharmacol. 2004 Apr 15;67(8):1469-78. | ||||||||||
| Title: | Cyclooxygenase-2 (COX-2)-dependent and -independent anticarcinogenic effects of celecoxib in human colon carcinoma cells. | ||||||||||
| Author: | Maier, Thorsten Jurgen|Schilling, Karin|Schmidt, Ronald|Geisslinger, Gerd|Grosch, Sabine | ||||||||||
| PMID: | 15041464 | ||||||||||
| 65. | |||||||||||
| Journal: | Int J Colorectal Dis. 2004 Jul;19(4):325-33. Epub 2004 Apr 2. | ||||||||||
| Title: | Immunohistochemical expression of cyclin D1, cyclin E, p21/waf1 and p27/kip1 in inflammatory bowel disease: correlation with other cell-cycle-related proteins (Rb, p53, ki-67 and PCNA) and clinicopathological features. | ||||||||||
| Author: | Ioachim, Elli E|Katsanos, Konstantinos H|Michael, Michael C|Tsianos, Epameinondas V|Agnantis, Niki J | ||||||||||
| PMID: | 15060836 | ||||||||||
| 66. | |||||||||||
| Journal: | Cancer. 2004 Apr 15;100(8):1615-21. | ||||||||||
| Title: | Alterations in the expression of the cell cycle regulatory protein cyclin kinase subunit 1 in colorectal carcinoma. | ||||||||||
| Author: | Shapira, Ma'anit|Ben-Izhak, Ofer|Bishara, Bishara|Futerman, Boris|Minkov, Ira|Krausz, Michael M|Pagano, Michele|Hershko, Dan D | ||||||||||
| PMID: | 15073847 | ||||||||||
| 67. | |||||||||||
| Journal: | Int J Hyperthermia. 2004 Jun;20(4):405-19. | ||||||||||
| Title: | Thermal enhancement of oxaliplatin-induced inhibition of cell proliferation and cell cycle progression in human carcinoma cell lines. | ||||||||||
| Author: | Atallah, D|Marsaud, V|Radanyi, C|Kornprobst, M|Rouzier, R|Elias, D|Renoir, J-M | ||||||||||
| PMID: | 15204521 | ||||||||||
| 68. | |||||||||||
| Journal: | Cancer Res. 2004 Sep 1;64(17):6050-7. | ||||||||||
| Title: | Hath1, down-regulated in colon adenocarcinomas, inhibits proliferation and tumorigenesis of colon cancer cells. | ||||||||||
| Author: | Leow, Ching Ching|Romero, Maria S|Ross, Sarajane|Polakis, Paul|Gao, Wei-Qiang | ||||||||||
| PMID: | 15342386 | ||||||||||
| 69. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2004 Nov 12;324(2):878-86. | ||||||||||
| Title: | Cell cycle-related signaling pathways modulated by peripheral benzodiazepine receptor ligands in colorectal cancer cells. | ||||||||||
| Author: | Maaser, Kerstin|Sutter, Andreas P|Krahn, Antje|Hopfner, Michael|Grabowski, Patricia|Scherubl, Hans | ||||||||||
| PMID: | 15474510 | ||||||||||
| 70. | |||||||||||
| Journal: | Am J Pathol. 2004 Nov;165(5):1489-98. | ||||||||||
| Title: | Colonic crypt changes during adenoma development in familial adenomatous polyposis: immunohistochemical evidence for expansion of the crypt base cell population. | ||||||||||
| Author: | Boman, Bruce M|Walters, Rhonda|Fields, Jeremy Z|Kovatich, Albert J|Zhang, Tao|Isenberg, Gerald A|Goldstein, Scott D|Palazzo, Juan P | ||||||||||
| PMID: | 15509520 | ||||||||||
| 71. | |||||||||||
| Journal: | World J Gastroenterol. 2004 Dec 1;10(23):3441-54. | ||||||||||
| Title: | Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis. | ||||||||||
| Author: | Xu, Xiao-Li|Yu, Jian|Zhang, Hong-Yu|Sun, Meng-Hong|Gu, Jun|Du, Xiang|Shi, Da-Ren|Wang, Peng|Yang, Zhen-Hua|Zhu, Jing-De | ||||||||||
| PMID: | 15526363 | ||||||||||
| 72. | |||||||||||
| Journal: | Mol Carcinog. 2005 Feb;42(2):109-20. | ||||||||||
| Title: | Tumorigenesis in p27/p53- and p18/p53-double null mice: functional collaboration between the pRb and p53 pathways. | ||||||||||
| Author: | Damo, Lorna A|Snyder, Paul W|Franklin, David S | ||||||||||
| PMID: | 15584024 | ||||||||||
| 73. | |||||||||||
| Journal: | Eur J Med Chem. 2005 Jan;40(1):85-92. | ||||||||||
| Title: | Synthesis and cytotoxic activity of 2-acyl-1H-indole-4,7-diones on human cancer cell lines. | ||||||||||
| Author: | Mahboobi, Siavosh|Sellmer, Andreas|Eichhorn, Emerich|Beckers, Thomas|Fiebig, Heinz-Herbert|Kelter, Gerhard | ||||||||||
| PMID: | 15642413 | ||||||||||
| 74. | |||||||||||
| Journal: | Cancer. 2005 Apr 1;103(7):1336-46. | ||||||||||
| Title: | The prognostic impact of the ubiquitin ligase subunits Skp2 and Cks1 in colorectal carcinoma. | ||||||||||
| Author: | Shapira, Ma'anit|Ben-Izhak, Ofer|Linn, Shai|Futerman, Boris|Minkov, Ira|Hershko, Dan D | ||||||||||
| PMID: | 15717322 | ||||||||||
| 75. | |||||||||||
| Journal: | Appl Immunohistochem Mol Morphol. 2005 Mar;13(1):38-44. | ||||||||||
| Title: | The clinical significance of p53, p21, and p27 expressions in rectal carcinoma. | ||||||||||
| Author: | Lebe, Banu|Sarioglu, Sulen|Sokmen, Selman|Ellidokuz, Hulya|Fuzun, Mehmet|Kupelioglu, Ali | ||||||||||
| PMID: | 15722792 | ||||||||||
| 76. | |||||||||||
| Journal: | Appl Immunohistochem Mol Morphol. 2005 Mar;13(1):45-54. | ||||||||||
| Title: | Prognostic significance of DCC and p27Kip1 in colorectal cancer. | ||||||||||
| Author: | Wu, James T|Kakar, Sanjay|Nelson, Richard L|Mihalov, Michael L|Hayward, Brooke|Gilbert, Peter B|Ghosh, Luna | ||||||||||
| PMID: | 15722793 | ||||||||||
| 77. | |||||||||||
| Journal: | Cell Signal. 2005 Jul;17(7):809-16. Epub 2004 Nov 24. | ||||||||||
| Title: | Ciglitazone-induced cellular anti-proliferation increases p27kip1 protein levels through both increased transcriptional activity and inhibition of proteasome degradation. | ||||||||||
| Author: | Chen, Fei|Harrison, Lawrence E | ||||||||||
| PMID: | 15763423 | ||||||||||
| 78. | |||||||||||
| Journal: | Am J Pathol. 2005 Apr;166(4):1239-46. | ||||||||||
| Title: | Inactivation of p21WAF1/cip1 enhances intestinal tumor formation in Muc2-/- mice. | ||||||||||
| Author: | Yang, Wancai|Velcich, Anna|Lozonschi, Ioana|Liang, Jiao|Nicholas, Courtney|Zhuang, Min|Bancroft, Laura|Augenlicht, Leonard H | ||||||||||
| PMID: | 15793302 | ||||||||||
| 79. | |||||||||||
| Journal: | Cancer Res. 2005 May 15;65(10):4253-60. | ||||||||||
| Title: | HER2 overexpression increases sensitivity to gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, through inhibition of HER2/HER3 heterodimer formation in lung cancer cells. | ||||||||||
| Author: | Hirata, Akira|Hosoi, Fumihito|Miyagawa, Miho|Ueda, Shu-ichi|Naito, Seiji|Fujii, Teruhiko|Kuwano, Michihiko|Ono, Mayumi | ||||||||||
| PMID: | 15899817 | ||||||||||
| 80. | |||||||||||
| Journal: | Food Chem Toxicol. 2005 Oct;43(10):1483-95. | ||||||||||
| Title: | Molecular mechanisms of econazole-induced toxicity on human colon cancer cells: G0/G1 cell cycle arrest and caspase 8-independent apoptotic signaling pathways. | ||||||||||
| Author: | Ho, Yuan-Soon|Wu, Chih-Hsiung|Chou, Hsiao-Min|Wang, Ying-Jan|Tseng, How|Chen, Chien-Ho|Chen, Li-Ching|Lee, Chia-Hwa|Lin, Shyr-Yi | ||||||||||
| PMID: | 15919146 | ||||||||||
| 81. | |||||||||||
| Journal: | Cell Signal. 2005 Dec;17(12):1572-7. | ||||||||||
| Title: | Ciglitazone-induced p27 gene transcriptional activity is mediated through Sp1 and is negatively regulated by the MAPK signaling pathway. | ||||||||||
| Author: | Chen, Fei|Kim, Eugene|Wang, Chia-Chi|Harrison, Lawrence E | ||||||||||
| PMID: | 15951157 | ||||||||||
| 82. | |||||||||||
| Journal: | J Biol Chem. 2005 Sep 9;280(36):32018-25. Epub 2005 Jul 6. | ||||||||||
| Title: | Cyclin-dependent kinase inhibitors uncouple cell cycle progression from mitochondrial apoptotic functions in DNA-damaged cancer cells. | ||||||||||
| Author: | Le, Hong-Van|Minn, Andy J|Massague, Joan | ||||||||||
| PMID: | 16002406 | ||||||||||
| 83. | |||||||||||
| Journal: | Am J Pathol. 2005 Oct;167(4):969-80. | ||||||||||
| Title: | |||||||||||