Primary Site >> Liver Cancer

Gene >> CDKN1A

1.
Journal: Cancer Res. 1995 Dec 15;55(24):6084-91.
Title: Mutant p53 but not hepatitis B virus X protein is present in hepatitis B virus-related human hepatocellular carcinoma.
Author: Henkler, F|Waseem, N|Golding, M H|Alison, M R|Koshy, R
PMID: 8521397
2.
Journal: Carcinogenesis. 1996 Aug;17(8):1647-55.
Title: Hepatocyte expression of tumor associated aldehyde dehydrogenase (ALDH-3) and p21 Ras following diethylnitrosamine (DEN) initiation and chronic exposure to di(2-ethylhexyl)phthalate (DHEP).
Author: Richmond, R E|Carter, J H|Carter, H W|Daniel, F B|Deangelo, A B
PMID: 8761421
3.
Journal: Int J Cancer. 1996 Sep 17;67(6):892-7.
Title: Inhibition of hepatitis-B-virus core promoter by p53: implications for carcinogenesis in hepatocytes.
Author: Uchida, T|Takahashi, K|Tatsuno, K|Dhingra, U|Eliason, J F
PMID: 8824564
4.
Journal: Cancer Lett. 1997 Jan 1;111(1-2):191-7.
Title: Decreased expression and rare somatic mutation of the CIP1/WAF1 gene in human hepatocellular carcinoma.
Author: Furutani, M|Arii, S|Tanaka, H|Mise, M|Niwano, M|Harada, T|Higashitsuji, H|Imamura, M|Fujita, J
PMID: 9022146
5.
Journal: Nihon Ika Daigaku Zasshi. 1997 Apr;64(2):147-53.
Title: [Laminin-dependent growth arrest of human hepatic carcinoma cell line, HuH-7, in association with expression of p21/WAF-1 protein].
Author: Arita, A|Asano, G|Tanaka, S|Nakazawa, N
PMID: 9128052
6.
Journal: J Biol Chem. 1997 May 30;272(22):14349-55.
Title: Membrane-anchored heparin-binding epidermal growth factor-like growth factor acts as a tumor survival factor in a hepatoma cell line.
Author: Miyoshi, E|Higashiyama, S|Nakagawa, T|Hayashi, N|Taniguchi, N
PMID: 9162071
7.
Journal: Gene. 1998 Feb 27;208(2):331-6.
Title: Hepatitis C virus core protein represses p21WAF1/Cip1/Sid1 promoter activity.
Author: Ray, R B|Steele, R|Meyer, K|Ray, R
PMID: 9524287
8.
Journal: Anticancer Res. 1998 Jan-Feb;18(1B):555-64.
Title: Protein expression of p53, p21WAF1, and Rb as prognostic indicators in patients with surgically treated hepatocellular carcinoma.
Author: Naka, T|Toyota, N|Kaneko, T|Kaibara, N
PMID: 9568177
9.
Journal: Int J Cancer. 1998 Aug 21;79(4):424-8.
Title: p21/WAF1, p53 and PCNA expression and p53 mutation status in hepatocellular carcinoma.
Author: Qin, L F|Ng, I O|Fan, S T|Ng, M
PMID: 9699537
10.
Journal: J Exp Med. 1998 Nov 2;188(9):1763-8.
Title: Two new p73 splice variants, gamma and delta, with different transcriptional activity.
Author: De Laurenzi, V|Costanzo, A|Barcaroli, D|Terrinoni, A|Falco, M|Annicchiarico-Petruzzelli, M|Levrero, M|Melino, G
PMID: 9802988
11.
Journal: Hepatogastroenterology. 1998 Sep-Oct;45(23):1635-42.
Title: Cell cycle regulators and human hepatocarcinogenesis.
Author: Hui, A M|Makuuchi, M|Li, X
PMID: 9840120
12.
Journal: J Gastroenterol Hepatol. 1998 Nov;13(S3):S299-S303.
Title: Molecular and cellular pathology of hepatocellular carcinoma.
Author: Ng, Irene Ol
PMID: 28976653
13.
Journal: Biochim Biophys Acta. 1999 Apr 1;1449(3):261-8.
Title: Cyclic AMP induces inhibition of cyclin A expression and growth arrest in human hepatoma cells.
Author: Lee, J|Choi, Y H|Nguyen, P|Kim, J S|Lee, S J|Trepel, J B
PMID: 10209305
14.
Journal: Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14961-6.
Title: Transforming growth factor beta targeted inactivation of cyclin E:cyclin-dependent kinase 2 (Cdk2) complexes by inhibition of Cdk2 activating kinase activity.
Author: Nagahara, H|Ezhevsky, S A|Vocero-Akbani, A M|Kaldis, P|Solomon, M J|Dowdy, S F
PMID: 10611320
15.
Journal: Zhonghua Gan Zang Bing Za Zhi. 1999 Dec;7(4):217-20.
Title: [WAF1/CIP1 gene expression in human hepatocellular carcinoma and its relationship with p53 mutation].
Author: Zhu, B|Cong, W|Wang, H
PMID: 10715791
16.
Journal: Hepatology. 2000 May;31(5):1080-5.
Title: Survivin promotes cell proliferation in human hepatocellular carcinoma.
Author: Ito, T|Shiraki, K|Sugimoto, K|Yamanaka, T|Fujikawa, K|Ito, M|Takase, K|Moriyama, M|Kawano, H|Hayashida, M|Nakano, T|Suzuki, A
PMID: 10796883
17.
Journal: Br J Cancer. 2000 Jul;83(1):50-5.
Title: Reduced p21(WAF1/CIP1) protein expression is predominantly related to altered p53 in hepatocellular carcinomas.
Author: Shi, Y Z|Hui, A M|Takayama, T|Li, X|Cui, X|Makuuchi, M
PMID: 10883667
18.
Journal: Oncogene. 2000 Jul 13;19(30):3384-94.
Title: Hepatitis B virus-X protein upregulates the expression of p21waf1/cip1 and prolongs G1-->S transition via a p53-independent pathway in human hepatoma cells.
Author: Park, U S|Park, S K|Lee, Y I|Park, J G|Lee, Y I
PMID: 10918595
19.
Journal: J Biol Chem. 2000 Nov 3;275(44):34122-30.
Title: Hepatitis C virus core protein enhances p53 function through augmentation of DNA binding affinity and transcriptional ability.
Author: Otsuka, M|Kato, N|Lan, K|Yoshida, H|Kato, J|Goto, T|Shiratori, Y|Omata, M
PMID: 10924497
20.
Journal: J Hepatol. 2000 Aug;33(2):254-65.
Title: P53 but not p16INK4a induces growth arrest in retinoblastoma-deficient hepatocellular carcinoma cells.
Author: Morel, A P|Unsal, K|Cagatay, T|Ponchel, F|Carr, B|Ozturk, M
PMID: 10952243
21.
Journal: World J Gastroenterol. 2000 Jun;6(3):356-360.
Title: Analysis of in vivo patterns of caspase 3 gene expression in primary hepatocellular carcinoma and its relationship to p21(WAF1) expression and hepatic apoptosis.
Author: Sun, Bao-Hua|Zhang, Jun|Wang, Bao-J|Zhao, Xi-Ping|Wang, You-Kun|Yu, Zhi-Qun|Yang, Dong-Liang|Hao, Lian-Jie
PMID: 11819597
22.
Journal: Methods Mol Med. 2000;45:167-73.
Title: Measurement of Protein Expression of p53, p21(WAF1), and Rb in Patients with Surgically Treated Hepatocellular Carcinoma by Using Catalyzed Signal-Amplification System.
Author: Naka, T|Kaneko, T|Kaibara, N
PMID: 21341055
23.
Journal: Hepatol Res. 2001 May 1;20(1):52-67.
Title: Correlation between p21(waf1) and p16(INK4a) expression in hepatocellular carcinoma.
Author: Fukushima, K|Ueno, Y|Yamagiwa, Y|Yamakawa, M|Iwasaki, T|Ishii, M|Toyota, T|Shimosegawa, T
PMID: 11282486
24.
Journal: Hepatology. 2001 May;33(5):1087-97.
Title: Involvement of p21(WAF1/Cip1), p27(Kip1), and p18(INK4c) in troglitazone-induced cell-cycle arrest in human hepatoma cell lines.
Author: Koga, H|Sakisaka, S|Harada, M|Takagi, T|Hanada, S|Taniguchi, E|Kawaguchi, T|Sasatomi, K|Kimura, R|Hashimoto, O|Ueno, T|Yano, H|Kojiro, M|Sata, M
PMID: 11343236
25.
Journal: J Biol Chem. 2001 Aug 3;276(31):29116-25.
Title: Sp1 plays a critical role in the transcriptional activation of the human cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by the p53 tumor suppressor protein.
Author: Koutsodontis, G|Tentes, I|Papakosta, P|Moustakas, A|Kardassis, D
PMID: 11384995
26.
Journal: Oncogene. 2001 Jun 21;20(28):3674-82.
Title: Distinctive gene expression profiles associated with Hepatitis B virus x protein.
Author: Wu, C G|Salvay, D M|Forgues, M|Valerie, K|Farnsworth, J|Markin, R S|Wang, X W
PMID: 11439330
27.
Journal: Cancer Gene Ther. 2001 May;8(5):333-41.
Title: The cytotoxic effect of E1B 55-kDa mutant adenovirus on human hepatocellular carcinoma cell lines.
Author: Zhao, J|Wang, H|Wei, L|Habib, N A|Lu, X|Wu, M|Guo, Y
PMID: 11477453
28.
Journal: Hum Pathol. 2001 Aug;32(8):778-84.
Title: Expression of p27(KIP1) and p21(WAF1/CIP1) in primary hepatocellular carcinoma: clinicopathologic correlation and survival analysis.
Author: Qin, L F|Ng, I O
PMID: 11521219
29.
Journal: J Gastroenterol Hepatol. 2001 Aug;16(8):883-9.
Title: Enhancement of tumor radioresponse by combined chemotherapy in murine hepatocarcinoma.
Author: Seong, J|Kim, S H|Suh, C O
PMID: 11555102
30.
Journal: Gene. 2001 Sep 5;275(1):163-8.
Title: Transcriptional repression of p21(waf1) promoter by hepatitis B virus X protein via a p53-independent pathway.
Author: Ahn, J Y|Chung, E Y|Kwun, H J|Jang, K L
PMID: 11574165
31.
Journal: Cancer Lett. 2001 Oct 22;172(1):7-15.
Title: Exogenous expression of p21(WAF1/CIP1) exerts cell growth inhibition and enhances sensitivity to cisplatin in hepatoma cells.
Author: Qin, L F|Ng, I O
PMID: 11595124
32.
Journal: Zhonghua Gan Zang Bing Za Zhi. 2001 Aug;9(4):237-9.
Title: [The effect of p53 gene on p-glycoprotein expression and chemotherapeutic cytotoxicity of hepatocellular carcinoma].
Author: Han, Y|Liang, L|Huang, J|Ming, W
PMID: 11602059
33.
Journal: Br J Cancer. 2002 Feb 12;86(4):625-9.
Title: A cyclin-dependent kinase inhibitor (p21(WAF1/CIP1)) affects thymidine incorporation in human liver cancer cells.
Author: Gong, Y|Deng, S|Zhang, M|Wang, G|Minuk, G Y|Burczynski, F
PMID: 11870547
34.
Journal: Biochem Biophys Res Commun. 2002 Mar 29;292(2):383-9.
Title: Attenuation of transforming growth factor beta-induced growth inhibition in human hepatocellular carcinoma cell lines by cyclin D1 overexpression.
Author: Jong, Hyun-Soon|Lee, Ho Soon|Kim, Tae You|Im, Young-Hyuck|Park, Jae-Won|Kim, Noe Kyeong|Bang, Yung-Jue
PMID: 11906173
35.
Journal: FEBS Lett. 2002 May 8;518(1-3):169-72.
Title: Cooperative repression of cyclin-dependent kinase inhibitor p21 gene expression by hepatitis B virus X protein and hepatitis C virus core protein.
Author: Han, Hae Jin|Jung, Eun Young|Lee, Woo Jung|Jang, Kyung Lib
PMID: 11997040
36.
Journal: Hum Pathol. 2002 Apr;33(4):429-34.
Title: High expression of p21WAF1/CIP1 is correlated with human hepatocellular carcinoma in patients with hepatitis C virus-associated chronic liver diseases.
Author: Wagayama, Hidetaka|Shiraki, Katsuya|Sugimoto, Kazushi|Ito, Takeshi|Fujikawa, Katsuhiko|Yamanaka, Takenari|Takase, Koujiro|Nakano, Takeshi
PMID: 12055678
37.
Journal: Int J Cancer. 2002 Jul 10;100(2):158-65.
Title: Effector mechanisms of norcantharidin-induced mitotic arrest and apoptosis in human hepatoma cells.
Author: Chen, Yan-Nian|Chen, Jung-Chou|Yin, Sui-Chu|Wang, Guang-Sheng|Tsauer, Wei|Hsu, Sheng-Feng|Hsu, Shih-Lan
PMID: 12115564
38.
Journal: Cancer Res. 2002 Jul 15;62(14):3997-4006.
Title: Growth inhibition of human hepatoma cells by acyclic retinoid is associated with induction of p21(CIP1) and inhibition of expression of cyclin D1.
Author: Suzui, Masumi|Masuda, Muneyuki|Lim, Jin T E|Albanese, Chris|Pestell, Richard G|Weinstein, I Bernard
PMID: 12124333
39.
Journal: Mol Cells. 2002 Jun 30;13(3):481-7.
Title: Quantification of tumor suppressor mRNA expression by poly-competitive RT-PCR using a TS-IS that contained multiple internal competitors.
Author: Jung, Hee-Jung|Chae, Ji Hyung|Kim, Hoguen|Park, Jeon Han|Lee, Jong Soo|Choi, Woong Hwan|Kim, Chul Geun
PMID: 12132590
40.
Journal: J Gen Virol. 2002 Sep;83(Pt 9):2145-51.
Title: Hepatitis C virus core protein represses the p21 promoter through inhibition of a TGF-beta pathway.
Author: Lee, Mi Nam|Jung, Eun Young|Kwun, Hyun Jin|Jun, Hong Ki|Yu, Dae-Yeul|Choi, Yung Hyun|Jang, Kyung Lib
PMID: 12185267
41.
Journal: J Hepatol. 2002 Oct;37(4):486-92.
Title: Infection of HepG2 cells with recombinant adenovirus encoding the HCV core protein induces p21(WAF1) down-regulation -- effect of transforming growth factor beta.
Author: Dubourdeau, Marc|Miyamura, Tatsuo|Matsuura, Yoshiharu|Alric, Laurent|Pipy, Bernard|Rousseau, Denis
PMID: 12217602
42.
Journal: World J Gastroenterol. 2002 Dec;8(6):1053-8.
Title: Effects of tachyplesin on proliferation and differentiation of human hepatocellular carcinoma SMMC-7721 cells.
Author: Ouyang, Gao-Liang|Li, Qi-Fu|Peng, Xuan-Xian|Liu, Qing-Rong|Hong, Shui-Gen
PMID: 12439924
43.
Journal: Mol Carcinog. 2003 Jan;36(1):15-22.
Title: Reduced expression of p27kip1 and increased hepatocyte proliferation in p53-deficient mice.
Author: Yang, Chuanwei|Sun, Mingzeng|Ilic, Zoran|Friedrich, Thomas D|Sell, Stewart
PMID: 12503075
44.
Journal: Arch Pharm Res. 2003 Feb;26(2):151-6.
Title: Inhibitory effects of luteolin isolated from Ixeris sonchifolia Hance on the proliferation of HepG2 human hepatocellular carcinoma cells.
Author: Yee, Su Bog|Lee, Jung Hwa|Chung, Hae Young|Im, Kwang Sik|Bae, Song Ja|Choi, Jae Soo|Kim, Nam Deuk
PMID: 12643593
45.
Journal: Zhonghua Bing Li Xue Za Zhi. 2003 Feb;32(1):43-7.
Title: [The role of hepatitis B virus X gene and p53 on hepatocellular carcinoma cell growth].
Author: Lin, Jing|Zhu, Ming-hua|Zhu, Shi|Qu, Jian-hui|Li, Fang-mei|Ni, Can-rong
PMID: 12760803
46.
Journal: Cancer Gene Ther. 2003 Jul;10(7):529-39.
Title: Systemic genetic transfer of p21WAF-1 and GM-CSF utilizing of a novel oligopeptide-based EGF receptor targeting polyplex.
Author: Liu, Xiang|Tian, Pei-Kun|Ju, Dian-Wen|Zhang, Min-Hui|Yao, Ming|Cao, Xue-Tao|Gu, Jian-Ren
PMID: 12833133
47.
Journal: Ai Zheng. 2003 Jul;22(7):680-5.
Title: [Determination of expression of eight p53-related genes in hepatocellular carcinoma with tissue microarrays].
Author: Zhu, Ming-Hua|Ni, Can-Rong|Zhu, Zhi|Li, Fang-Mei|Zhang, Shun-Min
PMID: 12866955
48.
Journal: Zhonghua Yi Xue Za Zhi. 2003 Oct 25;83(20):1795-800.
Title: [Study of cooperation of tumor suppressor p33(ING1b) with p53 gene in hepatocellular carcinoma].
Author: Zhu, Zhi|Lin, Jing|Qu, Jian-hui|Li, Fang-mei|Ni, Can-rong|Zhu, Ming-hua
PMID: 14642087
49.
Journal: Apoptosis. 2004 Mar;9(2):211-21.
Title: p53 dephosphorylation and p21(Cip1/Waf1) translocation correlate with caspase-3 activation in TGF-beta1-induced apoptosis of HuH-7 cells.
Author: Fan, G|Ma, X|Wong, P Y|Rodrigues, C M P|Steer, C J
PMID: 15004518
50.
Journal: Int J Oncol. 2004 Apr;24(4):797-805.
Title: Acyclic retinoid in the chemoprevention of hepatocellular carcinoma (review).
Author: Kojima, Soichi|Okuno, Masataka|Matsushima-Nishiwaki, Rie|Friedman, Scott L|Moriwaki, Hisataka
PMID: 15010815
51.
Journal: J Hepatol. 2004 Sep;41(3):436-45.
Title: Identification of genes up-regulated by histone deacetylase inhibition with cDNA microarray and exploration of epigenetic alterations on hepatoma cells.
Author: Chiba, Tetsuhiro|Yokosuka, Osamu|Arai, Makoto|Tada, Motohisa|Fukai, Kenichi|Imazeki, Fumio|Kato, Masaki|Seki, Naohiko|Saisho, Hiromitsu
PMID: 15336447
52.
Journal: Tsitologiia. 2004;46(4):301-11.
Title: [Different sensitivity of inbred mice to hepatocarcinogen ortho-aminoazotoluene may be due to differences in the negative control mechanisms of hepatocyte proliferation].
Author: Eremeev, A V|Timofeeva, O A|Kaledin, V I|Setkov, N A
PMID: 15346788
53.
Journal: Oncogene. 2004 Dec 9;23(57):9190-200.
Title: Inhibition of p53-mediated transcriptional responses by mithramycin A.
Author: Koutsodontis, George|Kardassis, Dimitris
PMID: 15489892
54.
Journal: J Biochem. 2004 Nov;136(5):701-9.
Title: Involvement of down-regulation of Cdk2 activity in hepatocyte growth factor-induced cell cycle arrest at G1 in the human hepatocellular carcinoma cell line HepG2.
Author: Tsukada, Yu-ichi|Tanaka, Toshiaki|Miyazawa, Keiji|Kitamura, Naomi
PMID: 15632311
55.
Journal: Int J Cancer. 2005 Mar 10;114(1):124-30.
Title: Novel inhibitors targeted to methionine aminopeptidase 2 (MetAP2) strongly inhibit the growth of cancers in xenografted nude model.
Author: Chun, Eunyoung|Han, Cheol Kyu|Yoon, Jeong Hyeok|Sim, Tae Bo|Kim, Yoon-Keun|Lee, Ki-Young
PMID: 15523682
56.
Journal: Oncogene. 2005 Jan 13;24(3):512-9.
Title: The expression of TA and DeltaNp63 are regulated by different mechanisms in liver cells.
Author: Petitjean, Audrey|Cavard, Catherine|Shi, Hong|Tribollet, Violaine|Hainaut, Pierre|Caron de Fromentel, Claude
PMID: 15543231
57.
Journal: Liver Int. 2005 Apr;25(2):445-57.
Title: Interleukin-6 inhibits cell proliferation in a rat model of hepatocellular carcinoma.
Author: Moran, Diarmuid M|Mayes, Nicholas|Koniaris, Leonidas G|Cahill, Paul A|McKillop, Iain H
PMID: 15780071
58.
Journal: World J Gastroenterol. 2005 Apr 7;11(13):1903-9.
Title: Inhibitory effect of tumor suppressor p33(ING1b) and its synergy with p53 gene in hepatocellular carcinoma.
Author: Zhu, Zhi|Lin, Jing|Qu, Jian-Hui|Feitelson, Mark-A|Ni, Can-Rong|Li, Fang-Mei|Zhu, Ming-Hua
PMID: 15800978
59.
Journal: Cancer Res. 2005 May 1;65(9):3691-9.
Title: Both antiangiogenesis- and angiogenesis-independent effects are responsible for hepatocellular carcinoma growth arrest by tyrosine kinase inhibitor PTK787/ZK222584.
Author: Liu, Yuqing|Poon, Ronnie T|Li, Qinyu|Kok, Tsz Wai|Lau, Cecilia|Fan, Sheung Tat
PMID: 15867364
60.
Journal: J Biol Chem. 2005 Sep 9;280(36):31548-56.
Title: Hepatocyte growth factor induces redistribution of p21(CIP1) and p27(KIP1) through ERK-dependent p16(INK4a) up-regulation, leading to cell cycle arrest at G1 in HepG2 hepatoma cells.
Author: Han, Junhong|Tsukada, Yu-ichi|Hara, Eiji|Kitamura, Naomi|Tanaka, Toshiaki
PMID: 16014626
61.
Journal: Biochem Pharmacol. 2005 Nov 25;70(11):1568-78.
Title: EGFR blockade by cetuximab alone or as combination therapy for growth control of hepatocellular cancer.
Author: Huether, Alexander|Hopfner, Michael|Baradari, Viola|Schuppan, Detlef|Scherubl, Hans
PMID: 16226226
62.
Journal: Hum Pathol. 2005 Nov;36(11):1154-62.
Title: GADD45-alpha expression in cirrhosis and hepatocellular carcinoma: relationship with DNA repair and proliferation.
Author: Gramantieri, Laura|Chieco, Pasquale|Giovannini, Catia|Lacchini, Michela|Trere, Davide|Grazi, Gian Luca|Venturi, Annamaria|Bolondi, Luigi
PMID: 16260267
63.
Journal: Food Chem Toxicol. 2006 Feb;44(2):227-35.
Title: Molecular mechanism of cell cycle blockage of hepatoma SK-Hep-1 cells by Epimedin C through suppression of mitogen-activated protein kinase activation and increased expression of CDK inhibitors p21(Cip1) and p27(Kip1).
Author: Liu, Tsan-Zon|Chen, Chung-Yi|Yiin, Shuenn-Jiun|Chen, Ching-Hsein|Cheng, Jiin-Tsuey|Shih, Ming-Kuei|Wang, Yu-Shan|Chern, Chi-Liang
PMID: 16112786
64.
Journal: Int J Oncol. 2006 May;28(5):1193-9.
Title: Acyclic retinoid, a novel synthetic retinoid, induces growth inhibition, apoptosis, and changes in mRNA expression of cell cycle- and differentiation-related molecules in human colon carcinoma cells.
Author: Suzui, Masumi|Sunagawa, Nao|Chiba, Itaru|Moriwaki, Hisataka|Yoshimi, Naoki
PMID: 16596235
65.
Journal: Cancer Res. 2006 Jul 1;66(13):6579-88.
Title: DDX3, a DEAD box RNA helicase with tumor growth-suppressive property and transcriptional regulation activity of the p21waf1/cip1 promoter, is a candidate tumor suppressor.
Author: Chao, Chi-Hong|Chen, Chun-Ming|Cheng, Pei-Lin|Shih, Jing-Wen|Tsou, Ann-Ping|Lee, Yan-Hwa Wu
PMID: 16818630
66.
Journal: Clin Cancer Res. 2006 Jul 15;12(14 Pt 1):4306-14.
Title: Xenografts of human hepatocellular carcinoma: a useful model for testing drugs.
Author: Huynh, Hung|Soo, Khee Chee|Chow, Pierce K H|Panasci, Lawrence|Tran, Evelyn
PMID: 16857806
67.
Journal: Acta Biochim Biophys Sin (Shanghai). 2006 Aug;38(8):523-30.
Title: Integrin beta(1A) upregulates p27 protein amount at the post-translational level in human hepatocellular carcinoma cell line SMMC-7721.
Author: Fu, Yi|Wang, Li-Ying|Liang, Yu-Long|Jin, Jia-Wei|Fang, Zheng-Yu|Zha, Xi-Liang
PMID: 16894473
68.
Journal: World J Gastroenterol. 2006 Aug 7;12(29):4673-82.
Title: Differential effects on apoptosis induction in hepatocyte lines by stable expression of hepatitis B virus X protein.
Author: Fiedler, Nicola|Quant, Ellen|Fink, Ludger|Sun, Jianguang|Schuster, Ralph|Gerlich, Wolfram H|Schaefer, Stephan
PMID: 16937438
69.
Journal: Mol Biol Rep. 2006 Dec;33(4):257-63.
Title: Introduction of G1 phase arrest in Human Hepatocellular carcinoma cells (HHCC) by APMCF1 gene transfection through the down-regulation of TIMP3 and up-regulation of the CDK inhibitors p21.
Author: Li, Qinlong|Yan, Wei|Cheng, Shengquan|Guo, Shuangping|Wang, Wenyong|Zhang, Zhipei|Wang, Li|Zhang, Jing|Wang, Wenliang
PMID: 17080297
70.
Journal: Ai Zheng. 2006 Dec;25(12):1470-6.
Title: [Synergistic inhibitory effect of all-trans retinoic acid and 1,25-dihydroxy vitamin D3 on growth of human hepatoma cell line HepG2].
Author: Lu, Hang-Qing|Zheng, Jie
PMID: 17166369
71.
Journal: BMC Cancer. 2006 Dec 14;6:286.
Title: Homeostatic response under carcinogen withdrawal, heme oxygenase 1 expression and cell cycle association.
Author: Castronuovo, Cynthia C|Sacca, Paula A|Meiss, Roberto|Caballero, Fabiana A|Batlle, Alcira|Vazquez, Elba S
PMID: 17169158
72.
Journal: Phytother Res. 2007 Jan;21(1):52-7.
Title: Methanol extract of the seaweed Gloiopeltis furcata induces G2/M arrest and inhibits cyclooxygenase-2 activity in human hepatocarcinoma HepG2 cells.
Author: Bae, Song Ja|Choi, Yung Hyun
PMID: 17078109
73.
Journal: J Cell Biochem. 2007 Jun 1;101(3):654-64.
Title: Increased expression of integrin beta1 subunit enhances p21WAF1/Cip1 transcription through the Sp1 sites and p300-mediated histone acetylation in human hepatocellular carcinoma cells.
Author: Fang, Zhengyu|Fu, Yi|Liang, Yulong|Li, Zengxia|Zhang, Wen|Jin, Jiawei|Yang, Yong|Zha, Xiliang
PMID: 17211849
74.
Journal: Cancer Biol Ther. 2007 Feb;6(2):238-44. Epub 2007 Feb 25.
Title: Forced expression of RDH10 gene retards growth of HepG2 cells.
Author: Rossi, Elena|Picozzi, Paola|Bodega, Beatrice|Lavazza, Cistiana|Carlo-Stella, Carmelo|Marozzi, Anna|Ginelli, Enrico
PMID: 17218779
75.
Journal: Oncogene. 2007 Jun 28;26(30):4428-34.
Title: In vivo regulation of p21 by the Kruppel-like factor 6 tumor-suppressor gene in mouse liver and human hepatocellular carcinoma.
Author: Narla, G|Kremer-Tal, S|Matsumoto, N|Zhao, X|Yao, S|Kelley, K|Tarocchi, M|Friedman, S L
PMID: 17297474
76.
Journal: Braz J Med Biol Res. 2007 May;40(5):621-31.
Title: TIMP-1 mediates the inhibitory effect of interleukin-6 on the proliferation of a hepatocarcinoma cell line in a STAT3-dependent manner.
Author: Guo, S-Y|Shen, X|Yang, J|Yuan, J|Yang, R-L|Mao, K|Zhao, D-H|Li, C-J
PMID: 17464423
77.
Journal: Liver Int. 2007 Jun;27(5):662-71.
Title: Hepatocyte senescence in end-stage chronic liver disease: a study of cyclin-dependent kinase inhibitor p21 in liver biopsies as a marker for progression to hepatocellular carcinoma.
Author: Brunt, Elizabeth M|Walsh, Sarah N|Hayashi, Paul H|Labundy, Jennifer|Di Bisceglie, Adrian M
PMID: 17498252
78.
Journal: Methods Find Exp Clin Pharmacol. 2007 Apr;29(3):179-83.
Title: Quercetin induces cell cycle G1 arrest through elevating Cdk inhibitors p21 and p27 in human hepatoma cell line (HepG2).
Author: Mu, C|Jia, P|Yan, Z|Liu, X|Li, X|Liu, H
PMID: 17520098
79.
Journal: Hepatology. 2007 Jul;46(1):48-57.
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Title: Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)-beta signaling from tumor suppression to oncogenesis in early chronic hepatitis B.
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Title: Inhibition of c-Jun NH2-terminal kinase switches Smad3 signaling from oncogenesis to tumor- suppression in rat hepatocellular carcinoma.
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Title: Plk1 regulates liver tumor cell death by phosphorylation of TAp63.
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Title: TGF-beta inactivation and TGF-alpha overexpression cooperate in an in vivo mouse model to induce hepatocellular carcinoma that recapitulates molecular features of human liver cancer.
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Title: Overexpression of transcriptional coactivator AIB1 promotes hepatocellular carcinoma progression by enhancing cell proliferation and invasiveness.
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Title: Genistein induces growth inhibition and G2/M arrest in nasopharyngeal carcinoma cells.
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Title: MicroRNA-125b suppressesed human liver cancer cell proliferation and metastasis by directly targeting oncogene LIN28B2.
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Title: Combined inhibitory effects of celecoxib and fluvastatin on the growth of human hepatocellular carcinoma xenografts in nude mice.
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Title: The transcription factors signal transducer and activator of transcription 5A (STAT5A) and STAT5B negatively regulate cell proliferation through the activation of cyclin-dependent kinase inhibitor 2b (Cdkn2b) and Cdkn1a expression.
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Title: Cardiotonic steroids attenuate ERK phosphorylation and generate cell cycle arrest to block human hepatoma cell growth.
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Title: Penta-1,2,3,4,6-O-galloyl-beta-D-glucose induces senescence-like terminal S-phase arrest in human hepatoma and breast cancer cells.
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Title: Aflatoxin genotoxicity is associated with a defective DNA damage response bypassing p53 activation.
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Title: Genotoxic effects of the cyanobacterial hepatotoxin cylindrospermopsin in the HepG2 cell line.
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Title: Suppression of TG-interacting factor sensitizes arsenic trioxide-induced apoptosis in human hepatocellular carcinoma cells.
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Title: MicroRNA-423 promotes cell growth and regulates G(1)/S transition by targeting p21Cip1/Waf1 in hepatocellular carcinoma.
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Title: Possible role of visfatin in hepatoma progression and the effects of branched-chain amino acids on visfatin-induced proliferation in human hepatoma cells.
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Title: Aberrant regulation of HDAC2 mediates proliferation of hepatocellular carcinoma cells by deregulating expression of G1/S cell cycle proteins.
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Title: Functional analysis of alpha1,3/4-fucosyltransferase VI in human hepatocellular carcinoma cells.
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Title: Ku80 functions as a tumor suppressor in hepatocellular carcinoma by inducing S-phase arrest through a p53-dependent pathway.
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Title: Synergistic growth inhibition of human hepatocellular carcinoma cells by acyclic retinoid and GW4064, a farnesoid X receptor ligand.
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Title: Human ESC self-renewal promoting microRNAs induce epithelial-mesenchymal transition in hepatocytes by controlling the PTEN and TGFbeta tumor suppressor signaling pathways.
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Title: N-Benzoyl-12-nitrodehydroabietylamine-7-one, a novel dehydroabietylamine derivative, induces apoptosis and inhibits proliferation in HepG2 cells.
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Title: Upregulator of cell proliferation predicts poor prognosis in hepatocellular carcinoma and contributes to hepatocarcinogenesis by downregulating FOXO3a.
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Journal: Oncol Rep. 2012 Nov;28(5):1551-8.
Title: Exosomes secreted from human colorectal cancer cell lines contain mRNAs, microRNAs and natural antisense RNAs, that can transfer into the human hepatoma HepG2 and lung cancer A549 cell lines.
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Journal: Autophagy. 2012 Dec;8(12):1856-8.
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Title: Swainsonine inhibits growth and potentiates the cytotoxic effect of paclitaxel in hepatocellular carcinoma in vitro and in vivo.
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Title: Preventive effects of branched-chain amino acid supplementation on the spontaneous development of hepatic preneoplastic lesions in C57BL/KsJ-db/db obese mice.
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Title: Hepatic gene expression analysis of 2-aminoanthracene exposed Fisher-344 rats reveal patterns indicative of liver carcinoma and type 2 diabetes.
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Title: Cisplatin induces HepG2 cell cycle arrest through targeting specific long noncoding RNAs and the p53 signaling pathway.
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Title: Antitumor Activities of the Novel Isosteviol Derivative 10C Against Liver Cancer.
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Title: HistoneH3 demethylase JMJD2A promotes growth of liver cancer cells through up-regulating miR372.
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Author: Li, Jinglin|Li, Zhenglong|Zheng, Wangyang|Li, Xinheng|Wang, Zhidong|Cui, Yunfu|Jiang, Xingming
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Title: TRIP6 promotes cell proliferation in hepatocellular carcinoma via suppression of FOXO3a.
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Journal: Oncotarget. 2017 Aug 1;8(51):88517-88528.
Title: MicroRNA deregulation in nonalcoholic steatohepatitis-associated liver carcinogenesis.
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Journal: Sci Rep. 2017 Dec 14;7(1):17609.
Title: Anti-IL-20 monoclonal antibody inhibited tumor growth in hepatocellular carcinoma.
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Title: Novel prognostic marker PRMT1 regulates cell growth via downregulation of CDKN1A in HCC.
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Journal: Int J Mol Sci. 2018 Jan 23;19(2). pii: ijms19020327.
Title: Regulation of Akt/FoxO3a/Skp2 Axis Is Critically Involved in Berberine-Induced Cell Cycle Arrest in Hepatocellular Carcinoma Cells.
Author: Li, Fanni|Dong, Xiwen|Lin, Peng|Jiang, Jianli
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Journal: Gene. 2018 Apr 20;651:183-193.
Title: Inhibition of hepatocellular carcinoma tumorigenesis by curcumin may be associated with CDKN1A and CTGF.
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Journal: Oncol Lett. 2018 Feb;15(2):1931-1936.
Title: Effects of harmaline on cell growth of human liver cancer through the p53/p21 and Fas/FasL signaling pathways.
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Journal: Oncol Rep. 2018 Apr;39(4):1975-1983.
Title: Melatonin induces the apoptosis and inhibits the proliferation of human gastric cancer cells via blockade of the AKT/MDM2 pathway.
Author: Song, Jun|Ma, Sai-Jun|Luo, Jian-Hua|Zhang, Hui|Wang, Ri-Xiong|Liu, Hui|Li, Li|Zhang, Zhi-Guang|Zhou, Rui-Xiang
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Journal: Cell Prolif. 2018 Jun;51(3):e12447.
Title: Pharmacological or transcriptional inhibition of both HDAC1 and 2 leads to cell cycle blockage and apoptosis via p21(Waf1/Cip1) and p19(INK4d) upregulation in hepatocellular carcinoma.
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Journal: Biomed Pharmacother. 2018 Jul;103:746-754.
Title: Naringenin improve hepatitis C virus infection induced insulin resistance by increase PTEN expression via p53-dependent manner.
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Journal: Med Sci Monit. 2018 May 24;24:3450-3461.
Title: Identification of Biological Targets of Therapeutic Intervention for Hepatocellular Carcinoma by Integrated Bioinformatical Analysis.
Author: Hu, Wei Qi|Wang, Wei|Fang, Di Long|Yin, Xue Feng
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Journal: Biochem Biophys Res Commun. 2018 Aug 25;502(4):515-521.
Title: Exosomal miR-93 promotes proliferation and invasion in hepatocellular carcinoma by directly inhibiting TIMP2/TP53INP1/CDKN1A.
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Journal: Oncol Lett. 2018 Jul;16(1):1291-1297.
Title: Liver kinase B1/adenosine monophosphate-activated protein kinase signaling axis induces p21/WAF1 expression in a p53-dependent manner.
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Journal: J Cancer Prev. 2018 Jun;23(2):63-69.
Title: Anti-proliferative Effect of 15,16-Dihydrotanshinone I Through Cell Cycle Arrest and the Regulation of AMP-activated Protein Kinase/Akt/mTOR and Mitogen-activated Protein Kinase Signaling Pathway in Human Hepatocellular Carcinoma Cells.
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Journal: PeerJ. 2018 Jul 18;6:e5203.
Title: Microarray gene expression profiling in colorectal (HCT116) and hepatocellular (HepG2) carcinoma cell lines treated with Melicope ptelefolia leaf extract reveals transcriptome profiles exhibiting anticancer activity.
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Journal: J Cell Biochem. 2018 Aug 20.
Title: Berberine: A potential adjunct for the treatment of gastrointestinal cancers?
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Journal: Gene. 2018 Oct 17;683:253-261.
Title: CircRNA has_circ_0078710 acts as the sponge of microRNA-31 involved in hepatocellular carcinoma progression.
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