Primary Site >> Colorectal Cancer

Gene >> CDKN1A

Journal: Dis Colon Rectum. 1989 Aug;32(8):665-8.
Title: Ras oncogene and the acquisition of metastasizing properties by rectal adenocarcinoma.
Author: Michelassi, F|Erroi, F|Roncella, M|Block, G E
PMID: 2666052
Journal: J Nucl Med. 1990 Sep;31(9):1520-6.
Title: Immunoscintigraphy of human tumors transplanted in nude mice with radiolabeled anti-ras p21 monoclonal antibodies.
Author: Katoh, Y|Nakata, K|Kohno, K|Shima, M|Satoh, A|Kusumoto, Y|Ishii, N|Kohji, T|Shiku, H|Nagataki, S
PMID: 2203882
Journal: Cell. 1993 Nov 19;75(4):817-25.
Title: WAF1, a potential mediator of p53 tumor suppression.
Author: el-Deiry, W S|Tokino, T|Velculescu, V E|Levy, D B|Parsons, R|Trent, J M|Lin, D|Mercer, W E|Kinzler, K W|Vogelstein, B
PMID: 8242752
Journal: Surg Today. 1993;23(1):89-91.
Title: DNA ploidy, c-myc oncoprotein p62 and v-H-ras oncoprotein p21 in colorectal carcinoma.
Author: Teranishi, T|Matsumoto, K|Ishijima, N|Miura, T|Suzuki, H
PMID: 8461612
Journal: Oncogene. 1995 Nov 16;11(10):1939-46.
Title: Induction of Fas-mediated apoptosis in p53-transfected human colon carcinoma cells.
Author: Tamura, T|Aoyama, N|Saya, H|Haga, H|Futami, S|Miyamoto, M|Koh, T|Ariyasu, T|Tachi, M|Kasuga, M
PMID: 7478511
Journal: J Biol Chem. 1995 Sep 29;270(39):22673-6.
Title: Activation of the p21 pathway of growth arrest and apoptosis by the beta 4 integrin cytoplasmic domain.
Author: Clarke, A S|Lotz, M M|Chao, C|Mercurio, A M
PMID: 7559386
Journal: Cancer Res. 1995 Apr 15;55(8):1649-54.
Title: Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline.
Author: Fan, S|Smith, M L|Rivet, D J 2nd|Duba, D|Zhan, Q|Kohn, K W|Fornace, A J Jr|O'Connor, P M
PMID: 7712469
Journal: Oncogene. 1995 Feb 2;10(3):599-601.
Title: Polymorphisms and probable lack of mutation in the WAF1-CIP1 gene in colorectal cancer.
Author: Li, Y J|Laurent-Puig, P|Salmon, R J|Thomas, G|Hamelin, R
PMID: 7845685
Journal: J Biol Chem. 1995 Mar 10;270(10):4971-4.
Title: Potential role of WAF1/Cip1/p21 as a mediator of TGF-beta cytoinhibitory effect.
Author: Li, C Y|Suardet, L|Little, J B
PMID: 7890601
Journal: Biochem Biophys Res Commun. 1996 Apr 16;221(2):207-12.
Title: DNA-dependent protein kinase inhibitor (OK-1035) suppresses p21 expression in HCT116 cells containing wild-type p53 induced by adriamycin.
Author: Take, Y|Kumano, M|Teraoka, H|Nishimura, S|Okuyama, A
PMID: 8619835
Journal: Cancer Res. 1996 May 15;56(10):2250-5.
Title: Repair Defect in p21 WAF1/CIP1 -/- human cancer cells.
Author: McDonald, E R 3rd|Wu, G S|Waldman, T|El-Deiry, W S
PMID: 8625293
Journal: Cancer Res. 1996 Feb 15;56(4):840-7.
Title: An abnormality in the p53 pathway following gamma-irradiation in many wild-type p53 human melanoma lines.
Author: Bae, I|Smith, M L|Sheikh, M S|Zhan, Q|Scudiero, D A|Friend, S H|O'Connor, P M|Fornace, A J Jr
PMID: 8631022
Journal: Oncogene. 1996 Feb 15;12(4):893-901.
Title: The anti-proliferative effect of sulindac and sulindac sulfide on HT-29 colon cancer cells: alterations in tumor suppressor and cell cycle-regulatory proteins.
Author: Goldberg, Y|Nassif, I I|Pittas, A|Tsai, L L|Dynlacht, B D|Rigas, B|Shiff, S J
PMID: 8632912
Journal: J Cancer Res Clin Oncol. 1996;122(6):360-5.
Title: The p53 gene is a potent determinant of chemosensitivity and radiosensitivity in gastric and colorectal cancers.
Author: Hamada, M|Fujiwara, T|Hizuta, A|Gochi, A|Naomoto, Y|Takakura, N|Takahashi, K|Roth, J A|Tanaka, N|Orita, K
PMID: 8642047
Journal: Oncogene. 1996 May 16;12(10):2057-67.
Title: Acute and delayed apoptosis induced by thymidine deprivation correlates with expression of p53 and p53-regulated genes in colon carcinoma cells.
Author: Harwood, F G|Frazier, M W|Krajewski, S|Reed, J C|Houghton, J A
PMID: 8668331
Journal: Br J Cancer. 1996 Jul;74(2):165-71.
Title: Clinical and pathological associations with p53 tumour-suppressor gene mutations and expression of p21WAF1/Cip1 in colorectal carcinoma.
Author: Slebos, R J|Baas, I O|Clement, M|Polak, M|Mulder, J W|van den Berg, F M|Hamilton, S R|Offerhaus, G J
PMID: 8688317
Journal: J Biol Chem. 1996 Aug 2;271(31):18961-5.
Title: Decorin-induced growth suppression is associated with up-regulation of p21, an inhibitor of cyclin-dependent kinases.
Author: De Luca, A|Santra, M|Baldi, A|Giordano, A|Iozzo, R V
PMID: 8702560
Journal: Genes Dev. 1996 Aug 1;10(15):1945-52.
Title: Genetic determinants of p53-induced apoptosis and growth arrest.
Author: Polyak, K|Waldman, T|He, T C|Kinzler, K W|Vogelstein, B
PMID: 8756351
Journal: Int J Cancer. 1996 Aug 22;69(4):259-64.
Title: Reduced messenger RNA expression level of p21 CIP1 in human colorectal carcinoma tissues and its association with p53 gene mutation.
Author: Matsushita, K|Kobayashi, S|Kato, M|Itoh, Y|Okuyama, K|Sakiyama, S|Isono, K
PMID: 8797864
Journal: Hum Pathol. 1996 Sep;27(9):912-6.
Title: Immunohistochemical detection of p21waf1/cip1/sdi1 and p53 proteins in formalin-fixed, paraffin-embedded tissue sections of colorectal carcinoma.
Author: Sasaki, K|Sato, T|Kurose, A|Ikeda, E
PMID: 8816885
Journal: Exp Cell Res. 1996 Sep 15;227(2):171-81.
Title: p21 (WAF1/CIP1) expression is induced in newly nondividing cells in diverse epithelia and during differentiation of the Caco-2 intestinal cell line.
Author: Gartel, A L|Serfas, M S|Gartel, M|Goufman, E|Wu, G S|el-Deiry, W S|Tyner, A L
PMID: 8831553
Journal: J Cell Physiol. 1996 Oct;169(1):200-8.
Title: c-Myc inactivation by mutant Max alters growth and morphology of NCI-H-630 colon cancer cells.
Author: Borre, A|Cultraro, C M|Segal, S
PMID: 8841436
Journal: Int J Cancer. 1996 Sep 27;68(1):126-31.
Title: Radio-induced modulation of transforming growth factor beta1 sensitivity in a p53 wild-type human colorectal-cancer cell line.
Author: Suardet, L|Li, C|Little, J B
PMID: 8895552
Journal: Nihon Rinsho. 1996 Apr;54(4):965-71.
Title: [RB gene expression in gastrointestinal tract].
Author: Monden, T|Yamamoto, H|Ikeda, K|Izawa, H|Tsujie, M|Ohnishi, T|Miyoshi, Y|Sekimoto, M|Tomita, N|Monden, M
PMID: 8920658
Journal: Oncol Res. 1996;8(7-8):317-23.
Title: Differential GADD45, p21CIP1/WAF1, MCL-1 and topoisomerase II gene induction and secondary DNA fragmentation after camptothecin-induced DNA damage in two mutant p53 human colon cancer cell lines.
Author: Goldwasser, F|Bae, I|Fornace, A J Jr|Pommier, Y
PMID: 8938795
Journal: Mol Cell Biol. 1996 Dec;16(12):6654-60.
Title: Protective role of p21(Waf1/Cip1) against prostaglandin A2-mediated apoptosis of human colorectal carcinoma cells.
Author: Gorospe, M|Wang, X|Guyton, K Z|Holbrook, N J
PMID: 8943319
Journal: Clin Cancer Res. 1996 Oct;2(10):1639-47.
Title: Wild-type p53 demonstrates functional dominance in a human colon carcinoma cell line in which it induces reversible growth arrest.
Author: Yang, B|Stambrook, P J|Markowitz, S D
PMID: 9816111
Journal: Clin Cancer Res. 1996 Jul;2(7):1221-9.
Title: Suppression of cancer cell growth by adenovirus expressing p21(WAF1/CIP1) deficient in PCNA interaction.
Author: Prabhu, N S|Blagosklonny, M V|Zeng, Y X|Wu, G S|Waldman, T|El-Deiry, W S
PMID: 9816291
Journal: J Cancer Res Clin Oncol. 1997;123(2):118-23.
Title: WAF1 expression and p53 mutations in human colorectal cancers.
Author: Wang, A|Yoshimi, N|Ino, N|Tanaka, T|Mori, H
PMID: 9030251
Journal: Oncogene. 1997 Apr 17;14(15):1875-82.
Title: Role of p21Waf1/Cip1/Sdi1 in cell death and DNA repair as studied using a tetracycline-inducible system in p53-deficient cells.
Author: Sheikh, M S|Chen, Y Q|Smith, M L|Fornace, A J Jr
PMID: 9150394
Journal: Oncogene. 1997 May 8;14(18):2127-36.
Title: Cells lacking CIP1/WAF1 genes exhibit preferential sensitivity to cisplatin and nitrogen mustard.
Author: Fan, S|Chang, J K|Smith, M L|Duba, D|Fornace, A J Jr|O'Connor, P M
PMID: 9174048
Journal: J Clin Invest. 1997 Jul 1;100(1):149-57.
Title: Ectopic expression of decorin protein core causes a generalized growth suppression in neoplastic cells of various histogenetic origin and requires endogenous p21, an inhibitor of cyclin-dependent kinases.
Author: Santra, M|Mann, D M|Mercer, E W|Skorski, T|Calabretta, B|Iozzo, R V
PMID: 9202067
Journal: Pathol Int. 1997 Jul;47(7):470-7.
Title: Expression of p21WAF1/CIP1 in colorectal adenomas and adenocarcinomas and its correlation with p53 protein expression.
Author: Yasui, W|Akama, Y|Yokozaki, H|Semba, S|Kudo, Y|Shimamoto, F|Tahara, E
PMID: 9234386
Journal: J Biol Chem. 1997 Aug 29;272(35):22199-206.
Title: Butyrate activates the WAF1/Cip1 gene promoter through Sp1 sites in a p53-negative human colon cancer cell line.
Author: Nakano, K|Mizuno, T|Sowa, Y|Orita, T|Yoshino, T|Okuyama, Y|Fujita, T|Ohtani-Fujita, N|Matsukawa, Y|Tokino, T|Yamagishi, H|Oka, T|Nomura, H|Sakai, T
PMID: 9268365
Journal: Arch Biochem Biophys. 1997 Oct 15;346(2):241-51.
Title: The role of NAD(P)H:quinone oxidoreductase in quinone-mediated p21 induction in human colon carcinoma cells.
Author: Qiu, X B|Cadenas, E
PMID: 9343371
Journal: Cancer Res. 1997 Nov 1;57(21):4703-6.
Title: Loss of p21Waf1/Cip1 sensitizes tumors to radiation by an apoptosis-independent mechanism.
Author: Wouters, B G|Giaccia, A J|Denko, N C|Brown, J M
PMID: 9354425
Journal: Nat Med. 1997 Nov;3(11):1233-41.
Title: Antioxidants enhance the cytotoxicity of chemotherapeutic agents in colorectal cancer: a p53-independent induction of p21WAF1/CIP1 via C/EBPbeta.
Author: Chinery, R|Brockman, J A|Peeler, M O|Shyr, Y|Beauchamp, R D|Coffey, R J
PMID: 9359698
Journal: Jpn J Cancer Res. 1997 Sep;88(9):855-60.
Title: Expressions of cell cycle regulators in human colorectal cancer cell lines.
Author: Tominaga, O|Nita, M E|Nagawa, H|Fujii, S|Tsuruo, T|Muto, T
PMID: 9369933
Journal: Chem Biol. 1997 Nov;4(11):783-9.
Title: Fiber-derived butyrate and the prevention of colon cancer.
Author: Hassig, C A|Tong, J K|Schreiber, S L
PMID: 9384528
Journal: Mol Cell. 1997 Dec;1(1):3-11.
Title: 14-3-3sigma is a p53-regulated inhibitor of G2/M progression.
Author: Hermeking, H|Lengauer, C|Polyak, K|He, T C|Zhang, L|Thiagalingam, S|Kinzler, K W|Vogelstein, B
PMID: 9659898
Journal: Semin Surg Oncol. 1998 Jan-Feb;14(1):3-12.
Title: Molecular changes during the genesis of human gliomas.
Author: Sehgal, A
PMID: 9407626
Journal: Oncogene. 1998 Jan 22;16(3):311-20.
Title: p21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells.
Author: Cayrol, C|Knibiehler, M|Ducommun, B
PMID: 9467956
Journal: J Biol Chem. 1998 Feb 20;273(8):4642-6.
Title: Transcriptional silencing of perlecan gene expression by interferon-gamma.
Author: Sharma, B|Iozzo, R V
PMID: 9468523
Journal: Oncogene. 1998 Feb 12;16(6):705-12.
Title: Mutated p21(WAF1/CIP1/SDI1) lacking CDK-inhibitory activity fails to prevent apoptosis in human colorectal carcinoma cells.
Author: Lu, Y|Yamagishi, N|Yagi, T|Takebe, H
PMID: 9488034
Journal: Dis Colon Rectum. 1998 Jan;41(1):68-74.
Title: Role of p53 and p21/WAF1 detection in patient selection for preoperative radiotherapy in rectal cancer patients.
Author: Fu, C G|Tominaga, O|Nagawa, H|Nita, M E|Masaki, T|Ishimaru, G|Higuchi, Y|Tsuruo, T|Muto, T
PMID: 9510313
Journal: Gastroenterology. 1998 May;114(5):940-6.
Title: Short-chain fatty acids induce cell cycle inhibitors in colonocytes.
Author: Wang, J|Friedman, E A
PMID: 9558282
Journal: Lab Invest. 1998 Apr;78(4):413-21.
Title: Protein kinase Calpha controls the adhesion but not the antiproliferative response of human colon carcinoma cells to transforming growth factor beta1: identification of two distinct branches of post-protein kinase Calpha adhesion signal pathway.
Author: Chakrabarty, S|Rajagopal, S|Moskal, T L
PMID: 9564886
Journal: Clin Cancer Res. 1998 May;4(5):1251-61.
Title: Loss of p21WAF1/Cip1 protein expression accompanies progression of sporadic colorectal neoplasms but not hereditary nonpolyposis colorectal cancers.
Author: Sinicrope, F A|Roddey, G|Lemoine, M|Ruan, S|Stephens, L C|Frazier, M L|Shen, Y|Zhang, W
PMID: 9607584
Journal: Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):6791-6.
Title: p21(WAF1) is required for butyrate-mediated growth inhibition of human colon cancer cells.
Author: Archer, S Y|Meng, S|Shei, A|Hodin, R A
PMID: 9618491
Journal: Cancer Res. 1998 Jul 1;58(13):2869-75.
Title: Mitochondrial membrane potential (delta psi(mt)) in the coordination of p53-independent proliferation and apoptosis pathways in human colonic carcinoma cells.
Author: Heerdt, B G|Houston, M A|Anthony, G M|Augenlicht, L H
PMID: 9661904
Journal: Int J Oncol. 1998 Aug;13(2):319-23.
Title: Mutational analysis of the p73 gene localized at chromosome 1p36.3 in colorectal carcinomas.
Author: Sunahara, M|Ichimiya, S|Nimura, Y|Takada, N|Sakiyama, S|Sato, Y|Todo, S|Adachi, W|Amano, J|Nakagawara, A
PMID: 9664127
Journal: Anticancer Res. 1998 May-Jun;18(3A):1479-84.
Title: Up-regulation of the tumor suppressor gene p53 and WAF1 gene expression by IP6 in HT-29 human colon carcinoma cell line.
Author: Saied, I T|Shamsuddin, A M
PMID: 9673359
Journal: J Biol Chem. 1998 Jul 31;273(31):19817-21.
Title: Cooperation of a single lysine mutation and a C-terminal domain in the cytoplasmic sequestration of the p53 protein.
Author: Liang, S H|Hong, D|Clarke, M F
PMID: 9677415
Journal: Ugeskr Laeger. 1998 Jul 20;160(30):4411-4.
Title: [Molecular effects of vitamin D on cell cycle and oncogenesis].
Author: Schmidt, J|Wittenhagen, P|Horder, M
PMID: 9691832
Journal: Nihon Geka Gakkai Zasshi. 1998 Jun;99(6):373-8.
Title: [A novel approach for cancer chemoprevention referred to as "gene-regulating chemoprevention"].
Author: Nakano, K|Yamagishi, H|Oka, T|Sakai, T
PMID: 9695075
Journal: Nihon Geka Gakkai Zasshi. 1998 Jul;99(7):457-62.
Title: [Messenger RNA expression of p21WAF1/CIP1 in colorectal carcinoma tissues].
Author: Kobayashi, S|Matsushita, K|Isono, K
PMID: 9742528
Journal: Oncogene. 1998 Sep 24;17(12):1567-75.
Title: Dexamethasone-mediated protection from drug cytotoxicity: association with p21WAF1/CIP1 protein accumulation?
Author: Naumann, U|Durka, S|Weller, M
PMID: 9794234
Journal: Am J Physiol. 1998 Nov;275(5 Pt 1):C1193-200.
Title: Caco-2 intestinal cell differentiation is associated with G1 arrest and suppression of CDK2 and CDK4.
Author: Ding, Q M|Ko, T C|Evers, B M
PMID: 9814966
Journal: Oncogene. 1998 Nov 12;17(19):2437-44.
Title: Interaction with cyclin-dependent kinases and PCNA modulates proteasome-dependent degradation of p21.
Author: Cayrol, C|Ducommun, B
PMID: 9824154
Journal: Oncogene. 1999 Jan 7;18(1):103-15.
Title: Comparative effects of overexpression of p27Kip1 and p21Cip1/Waf1 on growth and differentiation in human colon carcinoma cells.
Author: Yamamoto, H|Soh, J W|Shirin, H|Xing, W Q|Lim, J T|Yao, Y|Slosberg, E|Tomita, N|Schieren, I|Weinstein, I B
PMID: 9926925
Journal: Am J Gastroenterol. 1999 Feb;94(2):530-2.
Title: An aggressive desmoid tumor in a patient with familial adenomatous polyposis: immunohistochemical findings.
Author: Arai, N|Mitomi, H|Uesugi, H|Aihara, S|Ohtani, Y|Okayasu, I
PMID: 10022664
Journal: Mol Cell Biol. 1999 May;19(5):3916-28.
Title: Induction of p21(WAF1/CIP1) and inhibition of Cdk2 mediated by the tumor suppressor p16(INK4a).
Author: Mitra, J|Dai, C Y|Somasundaram, K|El-Deiry, W S|Satyamoorthy, K|Herlyn, M|Enders, G H
PMID: 10207115
Journal: Clin Cancer Res. 1999 May;5(5):1057-62.
Title: Paradoxical correlations of cyclin-dependent kinase inhibitors p21waf1/cip1 and p27kip1 in metastatic colorectal carcinoma.
Author: Cheng, J D|Werness, B A|Babb, J S|Meropol, N J
PMID: 10353738
Journal: Cell Tissue Res. 1999 May;296(2):221-7.
Title: Transforming growth factor-beta and p-21: multiple molecular targets of decorin-mediated suppression of neoplastic growth.
Author: Stander, M|Naumann, U|Wick, W|Weller, M
PMID: 10382266
Journal: Cancer Res. 1999 Jul 1;59(13):3245-50.
Title: Loss of P27Kip1 expression correlates with tumor grade and with reduced disease-free survival in primary superficial bladder cancers.
Author: Sgambato, A|Migaldi, M|Faraglia, B|Garagnani, L|Romano, G|De Gaetani, C|Ferrari, P|Capelli, G|Trentini, G P|Cittadini, A
PMID: 10397272
Journal: J Pathol. 1999 Feb;187(3):302-7.
Title: p21WAF1/CIP1 expression in colorectal carcinoma correlates with advanced disease stage and p53 mutations.
Author: Viale, G|Pellegrini, C|Mazzarol, G|Maisonneuve, P|Silverman, M L|Bosari, S
PMID: 10398083
Journal: J Clin Invest. 1999 Aug;104(3):263-9.
Title: Disruption of p53 in human cancer cells alters the responses to therapeutic agents.
Author: Bunz, F|Hwang, P M|Torrance, C|Waldman, T|Zhang, Y|Dillehay, L|Williams, J|Lengauer, C|Kinzler, K W|Vogelstein, B
PMID: 10430607
Journal: Biochem Biophys Res Commun. 1999 Aug 11;261(3):864-9.
Title: Isolation of differentially expressed cDNAs from p53-dependent apoptotic cells: activation of the human homologue of the Drosophila peroxidasin gene.
Author: Horikoshi, N|Cong, J|Kley, N|Shenk, T
PMID: 10441517
Journal: Br J Cancer. 1999 Sep;81(1):133-40.
Title: p22/WAF1 expression in human colorectal carcinoma: association with p53, transcription factor AP-2 and prognosis.
Author: Ropponen, K M|Kellokoski, J K|Lipponen, P K|Pietilainen, T|Eskelinen, M J|Alhava, E M|Kosma, V M
PMID: 10487624
Journal: Oncogene. 1999 Aug 26;18(34):4808-18.
Title: Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs.
Author: Chang, B D|Xuan, Y|Broude, E V|Zhu, H|Schott, B|Fang, J|Roninson, I B
PMID: 10490814
Journal: J Biol Chem. 1999 Nov 19;274(47):33637-43.
Title: Smad4/DPC4 silencing and hyperactive Ras jointly disrupt transforming growth factor-beta antiproliferative responses in colon cancer cells.
Author: Calonge, M J|Massague, J
PMID: 10559252
Journal: Scand J Gastroenterol. 1999 Nov;34(11):1162-7.
Title: A case of adenocarcinoma of the small intestine in a Japanese patient with Crohn disease: a report with immunohistochemical and oncogenic analyses.
Author: Uesugi, H|Mitomi, H|Sada, M|Takahashi, H|Kobayashi, K|Igarashi, M|Katsumata, T|Ihara, A|Ohtani, Y|Ikeda, S|Okayasu, I
PMID: 10582770
Journal: Int J Radiat Oncol Biol Phys. 1999 Dec 1;45(5):1167-73.
Title: Assessment of biomarkers in paired primary and recurrent colorectal adenocarcinomas.
Author: Seong, J|Chung, E J|Kim, H|Kim, G E|Kim, N K|Sohn, S K|Min, J S|Suh, C O
PMID: 10613309
Journal: Res Commun Mol Pathol Pharmacol. 1999;104(2):157-64.
Title: Effect of p53 tumor suppressor on nucleotide excision repair in human colon carcinoma cells treated with 4-nitroquinoline 1-oxide.
Author: Seo, Y R|Lee, S H|Han, S S|Ryu, J C
PMID: 10634308
Journal: Jpn J Cancer Res. 1999 Dec;90(12):1364-72.
Title: G1-checkpoint function including a cyclin-dependent kinase 2 regulatory pathway as potential determinant of 7-hydroxystaurosporine (UCN-01)-induced apoptosis and G1-phase accumulation.
Author: Akiyama, T|Sugiyama, K|Shimizu, M|Tamaoki, T|Akinaga, S
PMID: 10665655
Journal: Adv Exp Med Biol. 1999;469:555-61.
Title: Cyclooxygenase-independent induction of p21WAF-1/CIP1, apoptosis and differentiation by L-745,337 and salicylate in HT-29 colon cancer cells.
Author: Patrignani, P|Santini, G|Sciulli, M G|Marinacci, R|Fusco, O|Spoletini, L|Natoli, C|Procopio, A|Maclouf, J
PMID: 10667382
Journal: Int J Radiat Oncol Biol Phys. 1999 May 1;44(2):413-9.
Title: Association of increased radiocurability of murine carcinomas with low constitutive expression of p21(WAF1/CIP1) protein.
Author: Akimoto, T|Seong, J|Hunter, N R|Buchmiller, L|Mason, K|Milas, L
PMID: 10760438
Journal: Neoplasia. 1999 Dec;1(6):544-56.
Title: p53-independent inhibition of proliferation and p21(WAF1/Cip1)-modulated induction of cell death by the antioxidants N-acetylcysteine and vitamin E.
Author: Nargi, J L|Ratan, R R|Griffin, D E
PMID: 10935502
Journal: Carcinogenesis. 2000 Jan;21(1):7-14.
Title: Involvement of p21(Waf1/Cip1) and its cleavage by DEVD-caspase during apoptosis of colorectal cancer cells induced by butyrate.
Author: Chai, F|Evdokiou, A|Young, G P|Zalewski, P D
PMID: 10607727
Journal: Gastroenterology. 2000 Jan;118(1):81-9.
Title: Pyrrolidinedithiocarbamate increases the therapeutic index of 5-fluorouracil in a mouse model.
Author: Bach, S P|Chinery, R|O'Dwyer, S T|Potten, C S|Coffey, R J|Watson, A J
PMID: 10611156
Journal: Mol Cell Biol. 2000 Feb;20(3):760-9.
Title: HuR regulates p21 mRNA stabilization by UV light.
Author: Wang, W|Furneaux, H|Cheng, H|Caldwell, M C|Hutter, D|Liu, Y|Holbrook, N|Gorospe, M
PMID: 10629032
Journal: Cancer Res. 2000 Jan 1;60(1):156-63.
Title: p21WAF1 regulates anchorage-independent growth of HCT116 colon carcinoma cells via E-cadherin expression.
Author: Mueller, S|Cadenas, E|Schonthal, A H
PMID: 10646868
Journal: Carcinogenesis. 2000 Feb;21(2):331-5.
Title: Curcumin-containing diet inhibits diethylnitrosamine-induced murine hepatocarcinogenesis.
Author: Chuang, S E|Kuo, M L|Hsu, C H|Chen, C R|Lin, J K|Lai, G M|Hsieh, C Y|Cheng, A L
PMID: 10657978
Journal: Cancer Res. 2000 Feb 1;60(3):679-84.
Title: p21WAF1/CIP1 antisense therapy radiosensitizes human colon cancer by converting growth arrest to apoptosis.
Author: Tian, H|Wittmack, E K|Jorgensen, T J
PMID: 10676653
Journal: Biochem Biophys Res Commun. 2000 Mar 5;269(1):179-90.
Title: p21(WAF1/CIP1) inhibits initiator caspase cleavage by TRAIL death receptor DR4.
Author: Xu, S Q|El-Deiry, W S
PMID: 10694497
Journal: Cancer Res. 2000 Feb 15;60(4):1129-38.
Title: Induction of differentiation and apoptosis by ligands of peroxisome proliferator-activated receptor gamma in non-small cell lung cancer.
Author: Chang, T H|Szabo, E
PMID: 10706135
Journal: Int J Cancer. 2000 Jan 20;89(1):14-8.
Title: Prognostic impact of p21/waf1/cip1 in colorectal cancer.
Author: Zirbes, T K|Baldus, S E|Moenig, S P|Nolden, S|Kunze, D|Shafizadeh, S T|Schneider, P M|Thiele, J|Hoelscher, A H|Dienes, H P
PMID: 10719725
Journal: Clin Cancer Res. 2000 Mar;6(3):1113-8.
Title: Expression of cell cycle control proteins in primary colorectal tumors does not always predict expression in lymph node metastases.
Author: McKay, J A|Douglas, J J|Ross, V G|Curran, S|Ahmed, F Y|Loane, J F|Murray, G I|McLeod, H L
PMID: 10741741
Journal: Virchows Arch. 2000 Mar;436(3):224-8.
Title: Protein expression of p53, p21 (WAF1/CIP1), bcl-2, Bax, cyclin D1 and pRb in human colon carcinomas.
Author: Bukholm, I K|Nesland, J M
PMID: 10782880
Journal: Anticancer Res. 2000 Mar-Apr;20(2A):779-84.
Title: Induction of apoptosis in human gastric cancer by sodium butyrate.
Author: Litvak, D A|Hwang, K O|Evers, B M|Townsend, C M Jr
PMID: 10810354
Journal: Clin Cancer Res. 2000 May;6(5):2021-7.
Title: Photodynamic therapy with the phthalocyanine photosensitizer Pc 4 of SW480 human colon cancer xenografts in athymic mice.
Author: Whitacre, C M|Feyes, D K|Satoh, T|Grossmann, J|Mulvihill, J W|Mukhtar, H|Oleinick, N L
PMID: 10815928
Journal: J Pathol. 2000 Aug;191(4):361-7.
Title: Effect of mutation and conformation on the function of p53 in colorectal cancer.
Author: Webley, K M|Shorthouse, A J|Royds, J A
PMID: 10918210
Journal: Gastroenterology. 2000 Aug;119(2):323-32.
Title: Phenotypic and molecular characteristics of hyperplastic polyposis.
Author: Rashid, A|Houlihan, P S|Booker, S|Petersen, G M|Giardiello, F M|Hamilton, S R
PMID: 10930367
Journal: Cell Prolif. 2000 Jun;33(3):139-46.
Title: Sodium butyrate modulates cell cycle-related proteins in HT29 human colonic adenocarcinoma cells.
Author: Coradini, D|Pellizzaro, C|Marimpietri, D|Abolafio, G|Daidone, M G
PMID: 10959623
Journal: Int J Cancer. 2000 Oct 1;88(1):77-81.
Title: Cyclin D1 protein expression and gene polymorphism in colorectal cancer. Aberdeen Colorectal Initiative.
Author: McKay, J A|Douglas, J J|Ross, V G|Curran, S|Murray, G I|Cassidy, J|McLeod, H L
PMID: 10964085
Journal: Pol J Pathol. 2000;51(2):63-9.
Title: Comparative evaluation of the expression of cell cycle regulating proteins: cyclin D1, P53 and P21 (WAF1) in colorectal cancer.
Author: Pasz-Walczak, G|Kordek, R
PMID: 10974928
Journal: Int J Cancer. 2000 Aug 20;90(4):175-85.
Title: Survival of colorectal cancer cell lines treated with paclitaxel, radiation, and 5-FU: effect of TP53 or hMLH1 deficiency.
Author: Kennedy, A S|Harrison, G H|Mansfield, C M|Zhou, X J|Xu, J F|Balcer-Kubiczek, E K
PMID: 10993958
Journal: Urology. 2000 Oct 1;56(4):689-95.
Title: Cyclin-dependent kinase inhibitor P27(KIP1) is expressed preferentially in early stages of urothelial carcinoma.
Author: Franke, K H|Miklosi, M|Goebell, P|Clasen, S|Steinhoff, C|Anastasiadis, A G|Gerharz, C|Schulz, W A
PMID: 11018640
Journal: Eur J Biochem. 2000 Nov;267(21):6435-42.
Title: Butyrate metabolism upstream and downstream acetyl-CoA synthesis and growth control of human colon carcinoma cells.
Author: Leschelle, X|Delpal, S|Goubern, M|Blottiere, H M|Blachier, F
PMID: 11029587
Journal: Oncogene. 2000 Sep 21;19(40):4660-7.
Title: Repression of transforming growth factor-beta receptor type I promoter expression by Sp1 deficiency.
Author: Periyasamy, S|Ammanamanchi, S|Tillekeratne, M P|Brattain, M G
PMID: 11030155
Journal: Virchows Arch. 2000 Sep;437(3):241-7.
Title: p53 gene status and expression of p53, mdm2, and p21Waf1/Cip1 proteins in colorectal cancer.
Author: Veloso, M|Wrba, F|Kaserer, K|Heinze, G|Magalhaes, A|Herbst, F|Teleky, B
PMID: 11037343
Journal: Dis Colon Rectum. 2000 Oct;43(10 Suppl):S23-8.
Title: Apoptosis and its regulation in flat-type early colorectal carcinoma: comparison with that in polypoid-type early colorectal carcinoma.
Author: Ozawa, A|Konishi, F|Fukayama, M|Kanazawa, K
PMID: 11052474
Journal: Mol Med. 2000 Aug;6(8):693-704.
Title: A novel Ras antagonist regulates both oncogenic Ras and the tumor suppressor p53 in colon cancer cells.
Author: Halaschek-Wiener, J|Wacheck, V|Schlagbauer-Wadl, H|Wolff, K|Kloog, Y|Jansen, B
PMID: 11055588
Journal: Cancer. 2000 Nov 1;89(9):1893-900.
Title: Low dose fractionated radiation enhances the radiosensitization effect of paclitaxel in colorectal tumor cells with mutant p53.
Author: Chendil, D|Oakes, R|Alcock, R A|Patel, N|Mayhew, C|Mohiuddin, M|Gallicchio, V S|Ahmed, M M
PMID: 11064345
Journal: Int J Cancer. 2000 Dec 1;88(5):804-9.
Title: A novel MDM2 anti-sense oligonucleotide has anti-tumor activity and potentiates cytotoxic drugs acting by different mechanisms in human colon cancer.
Author: Tortora, G|Caputo, R|Damiano, V|Bianco, R|Chen, J|Agrawal, S|Bianco, A R|Ciardiello, F
PMID: 11072252
Journal: J Pharmacol Exp Ther. 2000 Dec;295(3):870-8.
Title: Roles of nuclear factor-kappaB, p53, and p21/WAF1 in daunomycin-induced cell cycle arrest and apoptosis.
Author: Hellin, A C|Bentires-Alj, M|Verlaet, M|Benoit, V|Gielen, J|Bours, V|Merville, M P
PMID: 11082419
Journal: Clin Chem Lab Med. 2000 Sep;38(9):893-7.
Title: The human multidrug resistance-associated protein (MRP) gene family: from biological function to drug molecular design.
Author: Ishikawa, T|Kuo, M T|Furuta, K|Suzuki, M
PMID: 11097346
Journal: Cytokine. 2000 Dec;12(12):1745-54.
Title: TNF-alpha induced p21(WAF1) but not Bax in colon cancer cells WiDr with mutated p53: important role of protein stabilization.
Author: Kobayashi, N|Takada, Y|Hachiya, M|Ando, K|Nakajima, N|Akashi, M
PMID: 11097743
Journal: J Antibiot (Tokyo). 2000 Oct;53(10):1191-200.
Title: Mechanism of cell cycle arrest caused by histone deacetylase inhibitors in human carcinoma cells.
Author: Kim, Y B|Ki, S W|Yoshida, M|Horinouchi, S
PMID: 11132966
Journal: Scand J Gastroenterol. 2000 Nov;35(11):1204-11.
Title: Expression of inducible nitric oxide synthase in colorectal cancer and its association with prognosis.
Author: Ropponen, K M|Kellokoski, J K|Lipponen, P K|Eskelinen, M J|Alanne, L|Alhava, E M|Kosma, V M
PMID: 11145294
Journal: Hum Pathol. 2000 Dec;31(12):1506-14.
Title: Colorectal carcinomas with high microsatellite instability: defining a distinct immunologic and molecular entity with respect to prognostic markers.
Author: Edmonston, T B|Cuesta, K H|Burkholder, S|Barusevicius, A|Rose, D|Kovatich, A J|Boman, B|Fry, R|Fishel, R|Palazzo, J P
PMID: 11150376
Journal: Cancer Res. 2000 Dec 15;60(24):7084-93.
Title: A role for the integrin alphavbeta8 in the negative regulation of epithelial cell growth.
Author: Cambier, S|Mu, D Z|O'Connell, D|Boylen, K|Travis, W|Liu, W H|Broaddus, V C|Nishimura, S L
PMID: 11156415
Journal: Neoplasia. 2000 Sep-Oct;2(5):441-8.
Title: 8-Cl-adenosine-induced inhibition of colorectal cancer growth in vitro and in vivo.
Author: Carlson, C C|Chinery, R|Burnham, L L|Dransfield, D T
PMID: 11191111
Journal: J Radiat Res. 2000 Dec;41(4):341-8.
Title: Inhibition of X-ray and doxorubicin-induced apoptosis by butyrolactone I, a CDK-specific inhibitor, in human tumor cells.
Author: Lu, Y|Takebe, H|Yagi, T
PMID: 11329882
Journal: Chin Med J (Engl). 2000 Oct;113(10):886-8.
Title: Change of apoptotic status in the human colorectal adenoma-carcinoma sequences and its correlation with carcinogenesis and prognosis.
Author: Li, L|Yan, L|Wang, Z|Liu, Z|Wei, Y|Huang, G
PMID: 11775833
Journal: J Biol Chem. 2001 Jan 12;276(2):1555-63.
Title: Oncogenic Ki-ras confers a more aggressive colon cancer phenotype through modification of transforming growth factor-beta receptor III.
Author: Yan, Z|Deng, X|Friedman, E
PMID: 11029459
Journal: Radiat Res. 2001 Jan;155(1 Pt 2):230-234.
Title: Mechanisms of radiation-induced neoplastic transformation of human bronchial epithelial cells.
Author: Zhao, Y L|Piao, C Q|Hall, E J|Hei, T K
PMID: 11121239
Journal: Cancer Res. 2001 Jan 15;61(2):565-9.
Title: Targeted inactivation of the p21(WAF1/cip1) gene enhances Apc-initiated tumor formation and the tumor-promoting activity of a Western-style high-risk diet by altering cell maturation in the intestinal mucosal.
Author: Yang, W C|Mathew, J|Velcich, A|Edelmann, W|Kucherlapati, R|Lipkin, M|Yang, K|Augenlicht, L H
PMID: 11212250
Journal: Am J Physiol Lung Cell Mol Physiol. 2001 Apr;280(4):L617-26.
Title: The role of p21(CIP1/WAF1) in growth of epithelial cells exposed to hyperoxia.
Author: Rancourt, R C|Keng, P C|Helt, C E|O'Reilly, M A
PMID: 11238001
Journal: Cancer Res. 2001 Feb 15;61(4):1493-9.
Title: Pharmacological inhibition of fatty acid synthase activity produces both cytostatic and cytotoxic effects modulated by p53.
Author: Li, J N|Gorospe, M|Chrest, F J|Kumaravel, T S|Evans, M K|Han, W F|Pizer, E S
PMID: 11245456
Journal: Chem Biol Interact. 2001 Mar 14;134(1):27-39.
Title: Antiproliferative activity and interactions with cell-cycle related proteins of the organotin compound triethyltin(IV)lupinylsulfide hydrochloride.
Author: Barbieri, F|Sparatore, F|Cagnoli, M|Bruzzo, C|Novelli, F|Alama, A
PMID: 11248220
Journal: Int J Oncol. 2001 Apr;18(4):855-62.
Title: RPR-115135, a new non peptidomimetic farnesyltransferase inhibitor, induces G0/G1 arrest only in serum starved cells.
Author: Russo, P|Ottoboni, C|Crippa, A|Riou, J F|O'Connor, P M
PMID: 11251185
Journal: Int J Oncol. 2001 May;18(5):997-1002.
Title: Synergistic effects of dexamethasone and genistein on the expression of Cdk inhibitor p21WAF1/CIP1 in human hepatocellular and colorectal carcinoma cells.
Author: Park, J H|Oh, E J|Choi, Y H|Kang, C D|Kang, H S|Kim, D K|Kang, K I|Yoo, M A
PMID: 11295047
Journal: Anticancer Res. 2001 Jan-Feb;21(1A):359-64.
Title: IGF-II down regulation associated cell cycle arrest in colon cancer cells exposed to phenolic antioxidant ellagic acid.
Author: Narayanan, B A|Re, G G
PMID: 11299762
Journal: Oncogene. 2001 Feb 8;20(6):659-68.
Title: A transcriptional activation function of p53 is dispensable for and inhibitory of its apoptotic function.
Author: Kokontis, J M|Wagner, A J|O'Leary, M|Liao, S|Hay, N
PMID: 11313999
Journal: Pathol Biol (Paris). 2001 Mar;49(2):115-23.
Title: [Expression of p21 WAF1/CIP1 protein in colorectal cancers: study of its relation to p53 mutation and Ki67 antigen expression].
Author: Chapusot, C|Assem, M|Martin, L|Chalabreyssse, L|Benhamiche, A M|Lignier, M A|Chauffert, B|Teyssier, J R|Faivre, J|Piard, F
PMID: 11317955
Journal: Biochem Biophys Res Commun. 2001 Apr 27;283(1):80-5.
Title: 1,25-Dihydroxycholecalciferol enhances butyrate-induced p21(Waf1/Cip1) expression.
Author: Gaschott, T|Wachtershauser, A|Steinhilber, D|Stein, J
PMID: 11322770
Journal: Dig Dis Sci. 2001 Apr;46(4):757-64.
Title: 8-Cl-adenosine induces differentiation in LS174T cells.
Author: Carlson, C C|Burnham, L L|Shanks, R A|Dransfield, D T
PMID: 11330409
Journal: J Biol Chem. 2001 Jul 13;276(28):25813-22.
Title: The p53-regulated cyclin-dependent kinase inhibitor, p21 (cip1, waf1, sdi1), is not required for global genomic and transcription-coupled nucleotide excision repair of UV-induced DNA photoproducts.
Author: Adimoolam, S|Lin, C X|Ford, J M
PMID: 11331289
Journal: Am J Physiol Gastrointest Liver Physiol. 2001 Jul;281(1):G37-43.
Title: Polyamine depletion arrests growth of IEC-6 and Caco-2 cells by different mechanisms.
Author: Ray, R M|McCormack, S A|Johnson, L R
PMID: 11408253
Journal: Oncogene. 2001 Jun 7;20(26):3387-98.
Title: p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents.
Author: Mahyar-Roemer, M|Roemer, K
PMID: 11423989
Journal: Mutat Res. 2001 Jul 12;486(2):155-64.
Title: Heterocyclic amine induced apoptotic response in the human lymphoblastoid cell line TK6 is linked to mismatch repair status.
Author: Duc, R|Leong-Morgenthaler, P M
PMID: 11425520
Journal: Int J Cancer. 2001 Sep 20;95(5):302-6.
Title: Subcellular localisation of cyclin D1 protein in colorectal tumours is associated with p21(WAF1/CIP1) expression and correlates with patient survival.
Author: Holland, T A|Elder, J|McCloud, J M|Hall, C|Deakin, M|Fryer, A A|Elder, J B|Hoban, P R
PMID: 11494229
Journal: J Virol. 2001 Oct;75(20):9844-56.
Title: Inactivation of p21 by E1A leads to the induction of apoptosis in DNA-damaged cells.
Author: Chattopadhyay, D|Ghosh, M K|Mal, A|Harter, M L
PMID: 11559818
Journal: Curr Med Chem. 2001 Oct;8(12):1487-503.
Title: Cell cycle regulation in the G1 phase: a promising target for the development of new chemotherapeutic anticancer agents.
Author: Owa, T|Yoshino, H|Yoshimatsu, K|Nagasu, T
PMID: 11562278
Journal: Toxicol Sci. 2001 Oct;63(2):214-22.
Title: p53-dependent induction of p21(Cip1/WAF1/Sdi1) protects against oxygen-induced toxicity.
Author: Helt, C E|Rancourt, R C|Staversky, R J|O'Reilly, M A
PMID: 11568365
Journal: J Biol Chem. 2001 Nov 30;276(48):45201-6.
Title: The G2/M regulator 14-3-3sigma prevents apoptosis through sequestration of Bax.
Author: Samuel, T|Weber, H O|Rauch, P|Verdoodt, B|Eppel, J T|McShea, A|Hermeking, H|Funk, J O
PMID: 11574543
Journal: Biochem Biophys Res Commun. 2001 Nov 2;288(3):690-6.
Title: Butyrate-induced differentiation of Caco-2 cells is mediated by vitamin D receptor.
Author: Gaschott, T|Werz, O|Steinmeyer, A|Steinhilber, D|Stein, J
PMID: 11676498
Journal: Dig Dis Sci. 2001 Oct;46(10):2187-98.
Title: Activation of cyclin E-dependent kinase activity in colorectal cancer.
Author: Cam, W R|Masaki, T|Shiratori, T Y|Kato, N|Okamoto, M|Yamaji, Y|Igarashi, K|Sano, T|Omata, M
PMID: 11680595
Journal: Pathol Res Pract. 2001;197(10):683-9.
Title: P21 (WAF1) expression in colorectal cancer: correlation with P53 and cyclin D1 expression, clinicopathological parameters and prognosis.
Author: Pasz-Walczak, G|Kordek, R|Faflik, M
PMID: 11700890
Journal: Clin Cancer Res. 2001 Nov;7(11):3336-42.
Title: The investigational new drug XK469 induces G(2)-M cell cycle arrest by p53-dependent and -independent pathways.
Author: Ding, Z|Parchment, R E|LoRusso, P M|Zhou, J Y|Li, J|Lawrence, T S|Sun, Y|Wu, G S
PMID: 11705845
Journal: Int J Oncol. 2001 Dec;19(6):1255-62.
Title: Docosahexaenoic acid regulated genes and transcription factors inducing apoptosis in human colon cancer cells.
Author: Narayanan, B A|Narayanan, N K|Reddy, B S
PMID: 11713597
Journal: J Exp Clin Cancer Res. 2001 Sep;20(3):413-8.
Title: Development of colonic neoplasms and expressions of p53 and p21 proteins in experimental colitis of mice induced by dextran sulfate sodium.
Author: Takesue, F|Korenaga, D|Yao, T|Kabashima, A|Sugimachi, K
PMID: 11718223
Journal: Exp Mol Med. 2001 Dec 31;33(4):209-19.
Title: p53 gene transfer does not enhance E2F-1-mediated apoptosis in human colon cancer cells.
Author: Draus, J M|Elliott, M J|Atienza, C Jr|Stilwell, A|Wong, S L|Dong, Y|Yang, H|McMasters, K M
PMID: 11795482
Journal: J Exp Clin Cancer Res. 2001 Dec;20(4):549-52.
Title: Cdk1/P34Cdc2 and P21waf expression in colorectal adenomas and carcinomas.
Author: Egilmez, R|Elagoz, S|Kanik, E A
PMID: 11876550
Journal: Zhonghua Yi Xue Za Zhi. 2001 Nov 10;81(21):1330-2.
Title: [The role of p21 (wafl/cip1) in human colorectal carcinoma cell apoptosis].
Author: Lu, Y|Cao, W
PMID: 16200730
Journal: J Inorg Biochem. 2002 Jan 1;88(1):25-36.
Title: Antiproliferative activity of mixed-ligand dien-Cu(II) complexes with thiazole, thiazoline and imidazole derivatives.
Author: Bolos, C A|Papazisis, K T|Kortsaris, A H|Voyatzi, S|Zambouli, D|Kyriakidis, D A
PMID: 11750022
Journal: Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):389-94.
Title: Molecular determinants of terminal growth arrest induced in tumor cells by a chemotherapeutic agent.
Author: Chang, Bey-Dih|Swift, Mari E|Shen, Mei|Fang, Jing|Broude, Eugenia V|Roninson, Igor B
PMID: 11752408
Journal: Biochem Biophys Res Commun. 2002 Jan 11;290(1):504-9.
Title: ZK 156718, a low calcemic, antiproliferative, and prodifferentiating vitamin D analog.
Author: Gaschott, Tanja|Steinmeyer, Andreas|Steinhilber, Dieter|Stein, Jurgen
PMID: 11779200
Journal: J Biol Chem. 2002 Mar 22;277(12):9870-9. Epub 2002 Jan 9.
Title: Transforming growth factor beta 1 induces proliferation in colon carcinoma cells by Ras-dependent, smad-independent down-regulation of p21cip1.
Author: Yan, Zhongfa|Kim, Geum-Yi|Deng, Xiaobing|Friedman, Eileen
PMID: 11784716
Journal: Int J Radiat Oncol Biol Phys. 2002 Mar 1;52(3):720-8.
Title: p53 expression in human rectal tissue after radiotherapy: upregulation in normal mucosa versus functional loss in rectal carcinomas.
Author: Marijnen, Corrie A M|Kapiteijn, Ellen|Nagtegaal, Iris D|Mulder-Stapel, Adri A|van de Velde, Cornelis J H|Schrier, Peter I|Peltenburg, Lucy T C|van Krieken, J Han J M
PMID: 11849795
Journal: Int J Cancer. 2002 Feb 20;97(6):732-9.
Title: Human papillomavirus type 16 E6-enhanced susceptibility to apoptosis induced by TNF in A2780 human ovarian cancer cell line.
Author: Vikhanskaya, Faina|Falugi, Carla|Valente, Piera|Russo, Patrizia
PMID: 11857347
Journal: J Nat Prod. 2002 Feb;65(2):210-4.
Title: Bioactive isomalabaricane triterpenes from the marine sponge Rhabdastrella globostellata.
Author: Tasdemir, Deniz|Mangalindan, Gina C|Concepcion, Gisela P|Verbitski, Sheryl M|Rabindran, Sridhar|Miranda, Miriam|Greenstein, Michael|Hooper, John N A|Harper, Mary Kay|Ireland, Chris M
PMID: 11858759
Journal: Cancer Lett. 2002 May 28;179(2):185-95.
Title: Troglitazone activates p21Cip/WAF1 through the ERK pathway in HCT15 human colorectal cancer cells.
Author: Kim, Jin-Ah|Park, Ki-Sook|Kim, Ha-Il|Oh, So-Young|Ahn, Yongho|Oh, Jong-Won|Choi, Kang-Yell
PMID: 11888673
Journal: Mutat Res. 2002 Mar 20;500(1-2):17-30.
Title: SN2 DNA-alkylating agent-induced phosphorylation of p53 and activation of p21 gene expression.
Author: Jaiswal, Aruna S|Narayan, Satya
PMID: 11890931
Journal: Carcinogenesis. 2002 Mar;23(3):403-10.
Title: Human cells deficient in p53 regulated p21(waf1/cip1) expression exhibit normal nucleotide excision repair of UV-induced DNA damage.
Author: Wani, Manzoor A|Wani, Gulzar|Yao, Jihonag|Zhu, Qianzheng|Wani, Altaf A
PMID: 11895854
Journal: Clin Cancer Res. 2002 Mar;8(3):863-9.
Title: Vitamin E succinate is a potent novel antineoplastic agent with high selectivity and cooperativity with tumor necrosis factor-related apoptosis-inducing ligand (Apo2 ligand) in vivo.
Author: Weber, Tobias|Lu, Min|Andera, Ladislav|Lahm, Harald|Gellert, Nina|Fariss, Marc W|Korinek, Vladimir|Sattler, Wolfgang|Ucker, David S|Terman, Alexei|Schroder, Andreas|Erl, Wolfgang|Brunk, Ulf T|Coffey, Robert J|Weber, Christian|Neuzil, Jiri
PMID: 11895920
Journal: Toxicol Appl Pharmacol. 2002 Apr 1;180(1):22-35.
Title: Antitumor effects of miconazole on human colon carcinoma xenografts in nude mice through induction of apoptosis and G0/G1 cell cycle arrest.
Author: Wu, Chih-Hsiung|Jeng, Jiiang-Huei|Wang, Ying-Jan|Tseng, Chia-Jen|Liang, Yu-Chih|Chen, Chien-Ho|Lee, Horng-Mo|Lin, Jen-Kun|Lin, Chien-Huang|Lin, Shyr-Yi|Li, Chung-Pei|Ho, Yuan-Soon
PMID: 11922774
Journal: Cancer Gene Ther. 2002 May;9(5):453-63.
Title: C-terminal deletion mutant p21(WAF1/CIP1) enhances E2F-1-mediated apoptosis in colon adenocarcinoma cells.
Author: Elliott, Mary Jane|Stilwell, Ariel|Dong, Yan Bin|Yang, Hai Liang|Wong, Sandra L|Wrightson, William R|Martin, Robert C G|McMasters, Kelly M
PMID: 11961668
Journal: Exp Mol Med. 2002 Mar 31;34(1):27-31.
Title: Differential modulation of zinc-stimulated p21(Cip/WAF1) and cyclin D1 induction by inhibition of PI3 kinase in HT-29 colorectal cancer cells.
Author: Oh, So-Young|Park, Ki-Sook|Kim, Jin-Ah|Choi, Kang-Yell
PMID: 11989975
Journal: Int J Colorectal Dis. 2002 Jan;17(1):11-9.
Title: p21, p27, cyclin D1, and p53 in rectal cancer: immunohistology with prognostic significance?
Author: Schwandner, O|Bruch, H P|Broll, R
PMID: 12018448
Journal: Exp Cell Res. 2002 Jun 10;276(2):214-22.
Title: The p53 stabilizing compound CP-31398 induces apoptosis by activating the intrinsic Bax/mitochondrial/caspase-9 pathway.
Author: Luu, Yvonne|Bush, Jason|Cheung, K-John Jr|Li, Gang
PMID: 12027451
Journal: Cancer Res. 2002 Jun 1;62(11):3113-9.
Title: 2-aroylindoles, a novel class of potent, orally active small molecule tubulin inhibitors.
Author: Beckers, Thomas|Reissmann, Thomas|Schmidt, Mathias|Burger, Angelika M|Fiebig, Heinz H|Vanhoefer, Udo|Pongratz, Herwig|Hufsky, Harald|Hockemeyer, Jorg|Frieser, Markus|Mahboobi, Siavosh
PMID: 12036922
Journal: Am J Clin Pathol. 2002 Jun;117(6):908-15.
Title: High apoptotic activity and low epithelial cell proliferation with underexpression of p21(WAF1/CIP1) and p27Kip1 of mucinous carcinomas of the colorectum: comparison with well-differentiated type.
Author: Akino, Fumiyuki|Mitomi, Hiroyuki|Nakamura, Takatoshi|Ohtani, Yoshimasa|Ichinoe, Masaaki|Okayasu, Isao
PMID: 12047142
Journal: Oncogene. 2002 May 9;21(20):3207-12.
Title: Human p14(ARF)-mediated cell cycle arrest strictly depends on intact p53 signaling pathways.
Author: Weber, H Oliver|Samuel, Temesgen|Rauch, Pia|Funk, Jens Oliver
PMID: 12082636
Journal: J Nutr. 2002 Jul;132(7):2082-6.
Title: Resveratrol enhances the differentiation induced by butyrate in caco-2 colon cancer cells.
Author: Wolter, Freya|Stein, Jurgen
PMID: 12097697
Journal: Cancer Res. 2002 Jul 15;62(14):3997-4006.
Title: Growth inhibition of human hepatoma cells by acyclic retinoid is associated with induction of p21(CIP1) and inhibition of expression of cyclin D1.
Author: Suzui, Masumi|Masuda, Muneyuki|Lim, Jin T E|Albanese, Chris|Pestell, Richard G|Weinstein, I Bernard
PMID: 12124333
Journal: J Biol Chem. 2002 Oct 4;277(40):37949-54. Epub 2002 Jul 31.
Title: Inactivation of p21WAF1 sensitizes cells to apoptosis via an increase of both p14ARF and p53 levels and an alteration of the Bax/Bcl-2 ratio.
Author: Javelaud, Delphine|Besancon, Francoise
PMID: 12151395
Journal: Cancer Res. 2002 Aug 1;62(15):4325-30.
Title: Sulfonamide anilides, a novel class of histone deacetylase inhibitors, are antiproliferative against human tumors.
Author: Fournel, Marielle|Trachy-Bourget, Marie-Claude|Yan, P Theresa|Kalita, Ann|Bonfils, Claire|Beaulieu, Carole|Frechette, Sylvie|Leit, Silvana|Abou-Khalil, Elie|Woo, Soon-Hyung|Delorme, Daniel|MacLeod, A Robert|Besterman, Jeffrey M|Li, Zuomei
PMID: 12154036
Journal: Cancer Biol Ther. 2002 Jan-Feb;1(1):47-55.
Title: The mutant p53-conformation modifying drug, CP-31398, can induce apoptosis of human cancer cells and can stabilize wild-type p53 protein.
Author: Takimoto, Rishu|Wang, Wenge|Dicker, David T|Rastinejad, Farzan|Lyssikatos, Joseph|el-Deiry, Wafik S
PMID: 12174820
Journal: Cancer Lett. 2002 Jul 26;181(2):187-94.
Title: Monoterpenes inhibit proliferation of human colon cancer cells by modulating cell cycle-related protein expression.
Author: Bardon, Sylvie|Foussard, Valerie|Fournel, Sophie|Loubat, Agnes
PMID: 12175534
Journal: Mutat Res. 2002 Aug 29;505(1-2):13-25.
Title: Efficient repair of bulky anti-BPDE DNA adducts from non-transcribed DNA strand requires functional p53 but not p21(waf1/cip1) and pRb.
Author: Wani, Manzoor A|El-Mahdy, Mohammed A|Hamada, Farid M|Wani, Gulzar|Zhu, Qianzheng|Wang, Qi-en|Wani, Altaf A
PMID: 12175902
Journal: Mol Carcinog. 2002 Sep;35(1):21-8.
Title: Involvement of both extracellular signal-regulated kinase and c-jun N-terminal kinase pathways in the 12-O-tetradecanoylphorbol-13-acetate-induced upregulation of p21(Cip1) in colon cancer cells.
Author: Lin, Shyr-Yi|Liang, Yu-Chih|Ho, Yuan-Soon|Tsai, Shu-Huei|Pan, Shiann|Lee, Wen-Sen
PMID: 12203364
Journal: J Biol Chem. 2002 Nov 22;277(47):45028-33. Epub 2002 Sep 10.
Title: Tumor suppressor activity of AP2alpha mediated through a direct interaction with p53.
Author: McPherson, Lisa A|Loktev, Alexander V|Weigel, Ronald J
PMID: 12226108
Journal: Int J Oncol. 2002 Oct;21(4):787-93.
Title: Value of expression of p21WAF1/CIP1 as a prognostic factor in advanced middle and lower rectal cancer patients treated with preoperative radio-chemotherapy.
Author: Sogawa, Nobuhito|Takiguchi, Nobuhiro|Koda, Keiji|Oda, Kenji|Satomi, Daisuke|Kato, Kazuki|Ishikura, Hiroshi|Miyazaki, Masaru
PMID: 12239617
Journal: J Cell Biochem. 2002;87(2):147-59.
Title: Ketoconazole potentiates terfenadine-induced apoptosis in human Hep G2 cells through inhibition of cytochrome p450 3A4 activity.
Author: Wang, Ying-Jan|Yu, Cheng-Fei|Chen, Li-Ching|Chen, Chien-Ho|Lin, Jen-Kun|Liang, Yu-Chih|Lin, Chien-Huang|Lin, Shyr-Yi|Chen, Chin-Fa|Ho, Yuan-Soon
PMID: 12244568
Journal: Mutat Res. 2002 Sep 30;506-507:91-9.
Title: Molecular and genetic toxicology of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Author: Gooderham, Nigel J|Zhu, Huijun|Lauber, Sandra|Boyce, Antony|Creton, Stuart
PMID: 12351148
Journal: J Clin Pathol. 2002 Oct;55(10):763-6.
Title: Loss of p21(WAF1) compartmentalisation in sebaceous carcinoma compared with sebaceous hyperplasia and sebaceous adenoma.
Author: McBride, S R|Leonard, N|Reynolds, N J
PMID: 12354803
Journal: Cancer Lett. 2002 Dec 10;187(1-2):77-86.
Title: 2-Methoxyestradiol induces p53-associated apoptosis of colorectal cancer cells.
Author: Carothers, A M|Hughes, S A|Ortega, D|Bertagnolli, M M
PMID: 12359354
Journal: J Biol Chem. 2002 Dec 13;277(50):48270-5. Epub 2002 Oct 8.
Title: Transcriptional activation of the MUC2 gene by p53.
Author: Ookawa, Keizou|Kudo, Toshihiro|Aizawa, Shu|Saito, Hiroshi|Tsuchida, Shigeki
PMID: 12374798
Journal: Carcinogenesis. 2002 Oct;23(10):1677-84.
Title: Tangeretin induces cell-cycle G1 arrest through inhibiting cyclin-dependent kinases 2 and 4 activities as well as elevating Cdk inhibitors p21 and p27 in human colorectal carcinoma cells.
Author: Pan, Min-Hsiung|Chen, Wei-Jen|Lin-Shiau, Shoei-Yn|Ho, Chi-Tang|Lin, Jen-Kun
PMID: 12376477
Journal: Biochem Biophys Res Commun. 2002 Oct 18;298(1):178-83.
Title: Hygrolidin induces p21 expression and abrogates cell cycle progression at G1 and S phases.
Author: Kawada, Manabu|Usami, Ihomi|Ohba, Shun|Someno, Tetsuya|Kim, Jin|Hayakawa, Yoichi|Nose, Kiyoshi|Ishizuka, Masaaki
PMID: 12379237
Journal: Cancer Res. 2002 Oct 15;62(20):5743-8.
Title: UCN-01 inhibits p53 up-regulation and abrogates gamma-radiation-induced G(2)-M checkpoint independently of p53 by targeting both of the checkpoint kinases, Chk2 and Chk1.
Author: Yu, Qiang|La Rose, JiHyun|Zhang, Hongliang|Takemura, Haruyuki|Kohn, Kurt W|Pommier, Yves
PMID: 12384533
Journal: Nature. 2002 Oct 17;419(6908):729-34.
Title: Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage.
Author: Seoane, Joan|Le, Hong-Van|Massague, Joan
PMID: 12384701
Journal: Eur Surg Res. 2002 Nov-Dec;34(6):389-96.
Title: Prognostic significance of p21 and p27 protein, apoptosis, clinical and histologic factors in rectal cancer without lymph node metastases.
Author: Schwandner, O|Bruch, H-P|Broll, R
PMID: 12403937
Journal: Cell. 2002 Oct 18;111(2):241-50.
Title: The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells.
Author: van de Wetering, Marc|Sancho, Elena|Verweij, Cornelis|de Lau, Wim|Oving, Irma|Hurlstone, Adam|van der Horn, Karin|Batlle, Eduard|Coudreuse, Damien|Haramis, Anna Pavlina|Tjon-Pon-Fong, Menno|Moerer, Petra|van den Born, Maaike|Soete, Gwen|Pals, Steven|Eiler
PMID: 12408868
Journal: Cell Cycle. 2002 Jan;1(1):90-6.
Title: The cyclin-dependent kinase inhibitor butyrolactone is a potent inhibitor of p21 (WAF1/CIP1 expression).
Author: Sax, Joanna K|Dash, Bipin C|Hong, Rui|Dicker, David T|El-Deiry, Wafik S
PMID: 12429914
Journal: Int J Oncol. 2002 Dec;21(6):1223-8.
Title: Prognostic values of radiation-induced p53 in adjacent normal mucosa and p21WAF1/CIP1 expression in rectal cancer patients.
Author: Yoshikawa, Reigetsu|Yanagi, Hidenori|Kusunoki, Masato|Fujiwara, Yoshinori|Noda, Masafumi|Hashimoto-Tamaoki, Tomoko|Yamamura, Takehira
PMID: 12429971
Journal: J Clin Invest. 2002 Dec;110(11):1717-27.
Title: Induction of the Cdk inhibitor p21 by LY83583 inhibits tumor cell proliferation in a p53-independent manner.
Author: Lodygin, Dimitri|Menssen, Antje|Hermeking, Heiko
PMID: 12464677
Journal: J Nutr. 2002 Dec;132(12):3804S-3808S.
Title: Short chain fatty acids and colon cancer.
Author: Augenlicht, Leonard H|Mariadason, John M|Wilson, Andrew|Arango, Diego|Yang, WanCai|Heerdt, Barbara G|Velcich, Anna
PMID: 12468628
Journal: Clin Cancer Res. 2002 Dec;8(12):3841-9.
Title: Tissue microarray molecular profiling of early, node-negative adenocarcinoma of the rectum: a comprehensive analysis.
Author: Hoos, Axel|Nissan, Aviram|Stojadinovic, Alexander|Shia, Jinru|Hedvat, Cyrus V|Leung, Denis H Y|Paty, Philip B|Klimstra, David|Cordon-Cardo, Carlos|Wong, W Douglas
PMID: 12473598
Journal: Eur J Cancer Prev. 2002 Aug;11 Suppl 2:S12-7.
Title: Environment-gene interactions in intestinal cancer.
Author: Augenlicht, Leonard H|Heerdt, Barbara G|Mariadason, John M|Yang, WanCai|Wilson, Andrew J|Fragale, Alessandra|Velcich, Anna
PMID: 12570330
Journal: Environ Health Prev Med. 2002 Jul;7(3):95-102.
Title: Types and amount of dietary fat and colon cancer risk: Prevention by omega-3 fatty acid-rich diets.
Author: Reddy, Bandaru S
PMID: 21432290
Journal: J Biol Chem. 2003 Jan 24;278(4):2101-5.
Title: Kruppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage.
Author: Yoon, Hong S|Chen, Xinming|Yang, Vincent W
PMID: 12427745
Journal: Int J Cancer. 2003 Jan 1;103(1):21-8.
Title: Rapid turnover of cell-cycle regulators found in Mirk/dyrk1B transfectants.
Author: Ewton, Daina Z|Lee, Kangmoon|Deng, Xiaobing|Lim, Seunghwan|Friedman, Eileen
PMID: 12455049
Journal: Biochem Pharmacol. 2003 Jan 1;65(1):121-9.
Title: Influence of p53 and p21(WAF1) expression on sensitivity of cancer cells to cladribine.
Author: Galmarini, Carlos Maria|Voorzanger, Nathalie|Falette, Nicole|Jordheim, Lars|Cros, Emeline|Puisieux, Alain|Dumontet, Charles
PMID: 12473386
Journal: J Pharmacol Exp Ther. 2003 Jan;304(1):37-47.
Title: c-myc down-regulation induces apoptosis in human cancer cell lines exposed to RPR-115135 (C31H29NO4), a non-peptidomimetic farnesyltransferase inhibitor.
Author: Russo, Patrizia|Arzani, Dario|Trombino, Sonya|Falugi, Carla
PMID: 12490573
Journal: Int J Cancer. 2003 Mar 1;103(6):833-9.
Title: Ectopic p21sdi1 gene transfer induces retinoic acid receptor beta expression and sensitizes human cancer cells to retinoid treatment.
Author: Teraishi, Fuminori|Kadowaki, Yoshihiko|Tango, Yasuhisa|Kawashima, Takeshi|Umeoka, Tatsuo|Kagawa, Shunsuke|Tanaka, Noriaki|Fujiwara, Toshiyoshi
PMID: 12516107
Journal: Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1931-6.
Title: PUMA mediates the apoptotic response to p53 in colorectal cancer cells.
Author: Yu, Jian|Wang, Zhenghe|Kinzler, Kenneth W|Vogelstein, Bert|Zhang, Lin
PMID: 12574499
Journal: Cancer Res. 2003 Mar 1;63(5):972-9.
Title: Modulation of inducible nitric oxide synthase and related proinflammatory genes by the omega-3 fatty acid docosahexaenoic acid in human colon cancer cells.
Author: Narayanan, Bhagavathi A|Narayanan, Narayanan K|Simi, Barbara|Reddy, Bandaru S
PMID: 12615711
Journal: Oncogene. 2003 Apr 10;22(14):2186-91.
Title: Platelet-activating factor activates mitogen-activated protein kinases, inhibits proliferation, induces differentiation and suppresses the malignant phenotype of human colon carcinoma cells.
Author: Wang, Hongmei|Chakrabarty, Subhas
PMID: 12687020
Journal: J Gene Med. 2003 Apr;5(4):287-99.
Title: 5-Fluorouracil efficiently enhanced apoptosis induced by adenovirus-mediated transfer of caspase-8 in DLD-1 colon cancer cells.
Author: Uchida, Hiroaki|Shinoura, Nobusada|Kitayama, Joji|Watanabe, Toshiaki|Nagawa, Hirokazu|Hamada, Hirofumi
PMID: 12692863
Journal: Oncol Res. 2003;13(6-10):405-8.
Title: A new method for determining the status of p53 in tumor cell lines of different origin.
Author: Gartel, Andrei L|Feliciano, Claudine|Tyner, Angela L
PMID: 12725531
Journal: Int J Oncol. 2003 Jul;23(1):181-8.
Title: All trans retinoic acid sensitizes colon cancer cells to hyperthermia cytotoxic effects.
Author: Callari, Daniela|Sinatra, Fulvia|Paravizzini, Gianluca|Libra, Massimo|Emmanuele, Giovanni|Fiore, Barbara|Pezzino, Maria Francesca|Rasa, Daria|Mazzarino, Maria Clorinda|D'Alessandro, Natale|Travali, Salvatore
PMID: 12792792
Journal: Int J Cancer. 2003 Aug 10;106(1):125-37.
Title: In vitro and in vivo studies of the anticancer action of terbinafine in human cancer cell lines: G0/G1 p53-associated cell cycle arrest.
Author: Lee, Wen-Sen|Chen, Rong-Jane|Wang, Ying-Jan|Tseng, How|Jeng, Jiiang-Huei|Lin, Shyr-Yi|Liang, Yu-Chih|Chen, Chien-Ho|Lin, Chien-Huang|Lin, Jen-Kun|Ho, Pei-Yin|Chu, Jan-Show|Ho, Wei-Lu|Chen, Li-Ching|Ho, Yuan-Soon
PMID: 12794767
Journal: Nihon Eiseigaku Zasshi. 2003 May;58(2):267-74.
Title: [Gene-regulating chemoprevention against cancer--as a model for "molecular-targeting prevention" of cancer].
Author: Sowa, Yoshihiro|Sakai, Toshiyuki
PMID: 12806965
Journal: Cancer Res. 2003 Jun 15;63(12):3340-6.
Title: Transforming growth factor beta 1 increases the stability of p21/WAF1/CIP1 protein and inhibits CDK2 kinase activity in human colon carcinoma FET cells.
Author: Gong, JianGen|Ammanamanchi, Sudhakar|Ko, Tien C|Brattain, Michael G
PMID: 12810668
Journal: Am J Physiol Gastrointest Liver Physiol. 2003 Dec;285(6):G1181-8.
Title: The ERK pathway involves positive and negative regulations of HT-29 colorectal cancer cell growth by extracellular zinc.
Author: Park, Ki-Sook|Lee, Nam-Gu|Lee, Ki-Hoo|Seo, Jeong Taeg|Choi, Kang-Yell
PMID: 12816758
Journal: Cancer Sci. 2003 Mar;94(3):286-91.
Title: Enhanced sensitivity to cis-diamminedichloroplatinum(II) of a human carcinoma cell line with mutated p53 gene by cyclin-dependent kinase inhibitor p21(WAF1) expression.
Author: Satou, Mamoru|Aizawa, Syu|Hayakari, Makoto|Ookawa, Keizou|Tsuchida, Shigeki
PMID: 12824923
Journal: J Biol Chem. 2003 Sep 19;278(38):36496-504. Epub 2003 Jul 7.
Title: Che-1 arrests human colon carcinoma cell proliferation by displacing HDAC1 from the p21WAF1/CIP1 promoter.
Author: Di Padova, Monica|Bruno, Tiziana|De Nicola, Francesca|Iezzi, Simona|D'Angelo, Carmen|Gallo, Rita|Nicosia, Daniela|Corbi, Nicoletta|Biroccio, Annamaria|Floridi, Aristide|Passananti, Claudio|Fanciulli, Maurizio
PMID: 12847090
Journal: Clin Cancer Res. 2003 Jul;9(7):2856-65.
Title: Antisense Bcl-xl down-regulation switches the response to topoisomerase I inhibition from senescence to apoptosis in colorectal cancer cells, enhancing global cytotoxicity.
Author: Hayward, Richard L|Macpherson, Janet S|Cummings, Jeff|Monia, Brett P|Smyth, John F|Jodrell, Duncan I
PMID: 12855666
Journal: Radiat Res. 2003 Aug;160(2):205-9.
Title: p21+/+ (CDKN1A+/+) and p21-/- (CDKN1A-/-) human colorectal carcinoma cells display equivalent amounts of thermal radiosensitization.
Author: Larsson, Carey|Ng, Cheng E
PMID: 12859231
Journal: Mol Pharmacol. 2003 Aug;64(2):382-94.
Title: Molecular modes of action of artesunate in tumor cell lines.
Author: Efferth, Thomas|Sauerbrey, Axel|Olbrich, Armin|Gebhart, Erich|Rauch, Pia|Weber, H Oliver|Hengstler, Jan G|Halatsch, Marc-Eric|Volm, Manfred|Tew, Kenneth D|Ross, Douglas D|Funk, Jens Oliver
PMID: 12869643
Journal: J Cancer Res Clin Oncol. 2003 Aug;129(8):449-55.
Title: Different apoptotic activity and p21(WAF1/CIP1), but not p27(Kip1), expression in serrated adenomas as compared with traditional adenomas and hyperplastic polyps of the colorectum.
Author: Mitomi, Hiroyuki|Sada, Miwa|Kobayashi, Kiyonori|Igarashi, Masahiro|Mori, Akio|Kanazawa, Hideki|Nishiyama, Yasuhiko|Ihara, Atsushi|Otani, Yoshimasa
PMID: 12884030
Journal: J Clin Oncol. 2003 Sep 15;21(18):3391-401.
Title: Dynamic expression profile of p21WAF1/CIP1 and Ki-67 predicts survival in rectal carcinoma treated with preoperative radiochemotherapy.
Author: Rau, Beate|Sturm, Isrid|Lage, Hermann|Berger, Stefan|Schneider, Ulrike|Hauptmann, Steffen|Wust, Peter|Riess, Hanno|Schlag, Peter M|Dorken, Bernd|Daniel, Peter T
PMID: 12885834
Journal: J Nutr. 2003 Aug;133(8):2682-7.
Title: Down-regulation of proliferating cell nuclear antigen gene expression occurs during cell cycle arrest induced by human fecal water in colonic HT-29 cells.
Author: Zeng, Huawei|Davis, Cindy D
PMID: 12888658
Journal: Recent Results Cancer Res. 2003;164:247-57.
Title: Short-chain fatty acids and colon cancer cells: the vitamin D receptor--butyrate connection.
Author: Gaschott, Tanja|Stein, Jurgen
PMID: 12899527
Journal: J Biol Chem. 2003 Oct 31;278(44):43586-94. Epub 2003 Aug 19.
Title: p21-dependent inhibition of colon cancer cell growth by mevastatin is independent of inhibition of G1 cyclin-dependent kinases.
Author: Ukomadu, Chinweike|Dutta, Anindya
PMID: 12930830
Journal: J Biol Chem. 2003 Nov 21;278(47):47119-28.
Title: RNAi-mediated HuR depletion leads to the inhibition of muscle cell differentiation.
Author: van der Giessen, Kate|Di-Marco, Sergio|Clair, Eveline|Gallouzi, Imed Eddine
PMID: 12944397
Journal: Oncogene. 2003 Sep 11;22(39):7942-9.
Title: CDX2, a homeobox transcription factor, upregulates transcription of the p21/WAF1/CIP1 gene.
Author: Bai, Yun-Qing|Miyake, Satoshi|Iwai, Takehisa|Yuasa, Yasuhito
PMID: 12970742
Journal: World J Gastroenterol. 2003 Sep;9(9):1976-80.
Title: Effects of DNA methylation on expression of tumor suppressor genes and proto-oncogene in human colon cancer cell lines.
Author: Fang, Jing-Yuan|Lu, Juan|Chen, Ying-Xuan|Yang, Li
PMID: 12970888
Journal: Endocr Relat Cancer. 2003 Sep;10(3):397-402.
Title: The Kruppel-like transcription factor 6 gene in sporadic pituitary tumours.
Author: Vax, V V|Gueorguiev, M|Dedov, I I|Grossman, A B|Korbonits, M
PMID: 14503916
Journal: Dig Liver Dis. 2003 Aug;35(8):557-65.
Title: Molecular mechanisms involved in the antiproliferative effect of two COX-2 inhibitors, nimesulide and NS-398, on colorectal cancer cell lines.
Author: Buecher, B|Broquet, A|Bouancheau, D|Heymann, M F|Jany, A|Denis, M G|Bonnet, C|Galmiche, J P|Blottiere, H M
PMID: 14567460
Journal: Br J Cancer. 2003 Nov 3;89(9):1757-65.
Title: c-Myc overexpression sensitises colon cancer cells to camptothecin-induced apoptosis.
Author: Arango, D|Mariadason, J M|Wilson, A J|Yang, W|Corner, G A|Nicholas, C|Aranes, M J|Augenlicht, L H
PMID: 14583781
Journal: Cancer Biol Ther. 2003 Sep-Oct;2(5):572-8.
Title: Apoptotic response to 5-fluorouracil treatment is mediated by reduced polyamines, non-autocrine Fas ligand and induced tumor necrosis factor receptor 2.
Author: Zhang, Wei|Ramdas, Latha|Shen, Weiping|Song, Sonya W|Hu, Limei|Hamilton, Stanley R
PMID: 14614330
Journal: Oncogene. 2003 Nov 13;22(51):8271-82.
Title: Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells.
Author: Agarwal, Chapla|Singh, Rana P|Dhanalakshmi, Sivanandhan|Tyagi, Anil K|Tecklenburg, Marianne|Sclafani, Robert A|Agarwal, Rajesh
PMID: 14614451
Journal: Int J Clin Oncol. 2003 Dec;8(6):352-6.
Title: Induction of apoptosis by p53, bax, bcl-2, and p21 expressed in colorectal cancer.
Author: Katsumata, Kenji|Sumi, Tetsuo|Tomioka, Hidenori|Aoki, Tatsuya|Koyanagi, Yasuhisa
PMID: 14663636
Journal: Nutr Cancer. 2003;46(2):197-201.
Title: Cell cycle dysregulation induced by cytoplasm of Lactococcus lactis ssp lactis in SNUC2A, a colon cancer cell line.
Author: Kim, Ji Yeon|Woo, Hee Jong|Kim, Young-Suk|Kim, Kyoung Heon|Lee, Hyong Joo
PMID: 14690796
Journal: J Biol Chem. 2004 Feb 6;279(6):5035-41.
Title: Requirement of Kruppel-like factor 4 in preventing entry into mitosis following DNA damage.
Author: Yoon, Hong S|Yang, Vincent W
PMID: 14627709
Journal: Int J Colorectal Dis. 2004 Jan;19(1):12-7.
Title: Establishment of a colonic adenoma cell line (GEKI-2): spectral karyotype analysis and functional characterization.
Author: Menzel, Thomas|Melcher, Ralph|Koehler, Sigrid|Dusel, Gerda|Backhaus, Kerstin|Ott, German|Breithaupt, Wolfram|Al-Taie, Oliver|Schauber, Jurgen|Gostner, Andrea|Scheppach, Wolfgang|Luhrs, Hardi
PMID: 14648095
Journal: Cell Cycle. 2004 Feb;3(2):205-11.
Title: Tocotrienol-rich fraction of palm oil activates p53, modulates Bax/Bcl2 ratio and induces apoptosis independent of cell cycle association.
Author: Agarwal, Mukesh K|Agarwal, Munna L|Athar, Mohammad|Gupta, Sanjay
PMID: 14712090
Journal: Biochem J. 2004 Apr 1;379(Pt 1):209-16.
Title: Molecular and functional consequences of Smad4 C-terminal missense mutations in colorectal tumour cells.
Author: De Bosscher, Karolien|Hill, Caroline S|Nicolas, Francisco J
PMID: 14715079
Journal: Biochem Biophys Res Commun. 2004 Jan 30;314(1):138-42.
Title: 9-Hydroxystearic acid upregulates p21(WAF1) in HT29 cancer cells.
Author: Calonghi, N|Cappadone, C|Pagnotta, E|Farruggia, G|Buontempo, F|Boga, C|Brusa, G L|Santucci, M A|Masotti, L
PMID: 14715257
Journal: Oncogene. 2004 Jan 15;23(2):395-402.
Title: Identification of Kruppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer.
Author: Zhao, Weidong|Hisamuddin, Irfan M|Nandan, Mandayam O|Babbin, Brian A|Lamb, Neil E|Yang, Vincent W
PMID: 14724568
Journal: Cancer Sci. 2004 Feb;95(2):186-92.
Title: p53-independent anti-tumor effects of the nitrogen-containing bisphosphonate zoledronic acid.
Author: Kuroda, Junya|Kimura, Shinya|Segawa, Hidekazu|Sato, Kiyoshi|Matsumoto, Seiji|Nogawa, Masaki|Yuasa, Takeshi|Kobayashi, Yutaka|Yoshikawa, Toshikazu|Ottmann, Oliver G|Maekawa, Taira
PMID: 14965371
Journal: World J Gastroenterol. 2004 Feb 15;10(4):540-4.
Title: Effects of epidermal growth factor and its signal transduction inhibitors on apoptosis in human colorectal cancer cells.
Author: Chao, Jane C J|Peng, Wen Li|Chen, Sheng-Hsuan
PMID: 14966913
Journal: Carcinogenesis. 2004 Jul;25(7):1227-36.
Title: Diallyl disulfide (DADS) increases histone acetylation and p21(waf1/cip1) expression in human colon tumor cell lines.
Author: Druesne, Nathalie|Pagniez, Anthony|Mayeur, Camille|Thomas, Muriel|Cherbuy, Claire|Duee, Pierre-Henri|Martel, Paule|Chaumontet, Catherine
PMID: 14976134
Journal: Mol Cancer Ther. 2004 Feb;3(2):169-78.
Title: Enhanced oxaliplatin-induced apoptosis following antisense Bcl-xl down-regulation is p53 and Bax dependent: Genetic evidence for specificity of the antisense effect.
Author: Hayward, Richard L|Macpherson, Janet S|Cummings, Jeff|Monia, Brett P|Smyth, John F|Jodrell, Duncan I
PMID: 14985457
Journal: Oncogene. 2004 Mar 4;23(9):1737-44.
Title: Enhanced sensitivity to irinotecan by Cdk1 inhibition in the p53-deficient HT29 human colon cancer cell line.
Author: Abal, Miguel|Bras-Goncalves, Rui|Judde, Jean-Gabriel|Fsihi, Hafida|De Cremoux, Patricia|Louvard, Daniel|Magdelenat, Henri|Robine, Sylvie|Poupon, Marie-France
PMID: 15001986
Journal: Int J Oncol. 2004 Apr;24(4):935-41.
Title: Influence of p53 and p21Waf1 expression on G2/M phase arrest of colorectal carcinoma HCT116 cells to proteasome inhibitors.
Author: Kim, On Hee|Lim, Jun Hee|Woo, Kyung Jin|Kim, Young-Ho|Jin, Ing-Nyol|Han, Sang Tae|Park, Jong-Wook|Kwon, Taeg Kyu
PMID: 15010833
Journal: Biochem Pharmacol. 2004 Apr 15;67(8):1469-78.
Title: Cyclooxygenase-2 (COX-2)-dependent and -independent anticarcinogenic effects of celecoxib in human colon carcinoma cells.
Author: Maier, Thorsten Jurgen|Schilling, Karin|Schmidt, Ronald|Geisslinger, Gerd|Grosch, Sabine
PMID: 15041464
Journal: Zhonghua Yi Xue Za Zhi. 2004 Feb 17;84(4):312-7.
Title: [Regulation of histone acetylation on the expression of cell cycle-associated genes in human colon cancer cell lines].
Author: Chen, Ying-xuan|Fang, Jing-yuan|Lu, Juan|Qiu, De-kai
PMID: 15059516
Journal: Int J Colorectal Dis. 2004 Jul;19(4):325-33. Epub 2004 Apr 2.
Title: Immunohistochemical expression of cyclin D1, cyclin E, p21/waf1 and p27/kip1 in inflammatory bowel disease: correlation with other cell-cycle-related proteins (Rb, p53, ki-67 and PCNA) and clinicopathological features.
Author: Ioachim, Elli E|Katsanos, Konstantinos H|Michael, Michael C|Tsianos, Epameinondas V|Agnantis, Niki J
PMID: 15060836
Journal: Int J Oncol. 2004 May;24(5):1279-88.
Title: Molecular characterizations of derivatives of HCT116 colorectal cancer cells that are resistant to the chemotherapeutic agent 5-fluorouracil.
Author: de Angelis, Paula M|Fjell, Bjorg|Kravik, Katherine L|Haug, Terje|Tunheim, Siv H|Reichelt, Wenche|Beigi, Marzieh|Clausen, Ole Petter|Galteland, Eivind|Stokke, Trond
PMID: 15067352
Journal: Oncol Rep. 2004 May;11(5):951-6.
Title: Comparative analysis of cell adhesion molecules, cell cycle regulatory proteins, mismatch repair genes, cyclooxygenase-2, and DPC4 in carcinomas arising in inflammatory bowel disease and sporadic colon cancer.
Author: Hill, Kalisha A|Wang, Kim L|Stryker, Steven J|Gupta, Rohit|Weinrach, David M|Rao, M S
PMID: 15069531
Journal: Oncogene. 2004 Jul 8;23(31):5340-9.
Title: Histone deacetylase inhibitors activate INK4d gene through Sp1 site in its promoter.
Author: Yokota, Tomoya|Matsuzaki, Youichirou|Miyazawa, Kazuhiro|Zindy, Frederique|Roussel, Martine F|Sakai, Toshiyuki
PMID: 15107822
Journal: Exp Mol Pathol. 2004 Jun;76(3):196-204.
Title: CD44 negatively regulates apoptosis in murine colonic epithelium via the mitochondrial pathway.
Author: Lakshman, Minalini|Subramaniam, Venkateswaran|Jothy, Serge
PMID: 15126101
Journal: Prostaglandins Other Lipid Mediat. 2004 Jan;73(1-2):111-22.
Title: 15-LOX-1 inhibits p21 (Cip/WAF 1) expression by enhancing MEK-ERK 1/2 signaling in colon carcinoma cells.
Author: Yoshinaga, Masahiro|Buchanan, F Gregory|DuBois, Raymond N
PMID: 15165036
Journal: Cancer Res. 2004 Jun 1;64(11):3885-91.
Title: Cyclin-dependent kinase inhibition by the KLF6 tumor suppressor protein through interaction with cyclin D1.
Author: Benzeno, Sharon|Narla, Goutham|Allina, Jorge|Cheng, George Z|Reeves, Helen L|Banck, Michaela S|Odin, Joseph A|Diehl, J Alan|Germain, Doris|Friedman, Scott L
PMID: 15172998
Journal: Cancer Res. 2004 Jun 1;64(11):3966-73.
Title: Activation of protein kinase G is sufficient to induce apoptosis and inhibit cell migration in colon cancer cells.
Author: Deguchi, Atsuko|Thompson, W Joseph|Weinstein, I Bernard
PMID: 15173009
Journal: Environ Mol Mutagen. 2004;44(1):3-9.
Title: Nitric oxide and p53 in cancer-prone chronic inflammation and oxyradical overload disease.
Author: Goodman, Julie E|Hofseth, Lorne J|Hussain, S Perwez|Harris, Curtis C
PMID: 15199542
Journal: Int J Oncol. 2004 Jul;25(1):231-6.
Title: Synthetic bile acid derivatives inhibit cell proliferation and induce apoptosis in HT-29 human colon cancer cells.
Author: Park, Sang Eun|Choi, Hye Joung|Yee, Su Bog|Chung, Hae Young|Suh, Hongsuk|Choi, Yung Hyun|Yoo, Young Hyun|Kim, Nam Deuk
PMID: 15202011
Journal: Eur J Biochem. 2004 Jul;271(13):2773-81.
Title: The in vitro effects of CRE-decoy oligonucleotides in combination with conventional chemotherapy in colorectal cancer cell lines.
Author: Liu, Wai M|Scott, Katherine A|Shahin, Sipra|Propper, David J
PMID: 15206942
Journal: Nutr Cancer. 2004;48(2):198-206.
Title: Mechanism of sulforaphane-induced cell cycle arrest and apoptosis in human colon cancer cells.
Author: Parnaud, Geraldine|Li, PengFei|Cassar, Georges|Rouimi, Patrick|Tulliez, Jacques|Combaret, Lydie|Gamet-Payrastre, Laurence
PMID: 15231455
Journal: Zhonghua Bing Li Xue Za Zhi. 2004 Jun;33(3):247-50.
Title: [Growth suppression of colon cancer cells in vitro by DPC4 gene expression and its mechanism].
Author: Liu, Yang|Wen, Ji-Fang|Li, Jing-He|Xiao, De-Sheng|Hu, Zhong-Liang|Luo, Geng-Qiu
PMID: 15256118
Journal: J Biol Chem. 2004 Sep 17;279(38):40237-44. Epub 2004 Jul 22.
Title: Autocrine and exogenous transforming growth factor beta control cell cycle inhibition through pathways with different sensitivity.
Author: Wang, Jing|Sergina, Natalia|Ko, Tien C|Gong, Jiangeng|Brattain, Michael G
PMID: 15271980
Journal: Int J Oncol. 2004 Sep;25(3):661-70.
Title: Flavone inhibition of tumor growth via apoptosis in vitro and in vivo.
Author: Chen, Yen-Chou|Shen, Shing-Chuan|Chow, Jyh-Ming|Ko, Ching Huai|Tseng, Shih-Wen
PMID: 15289867
Journal: Cancer Res. 2004 Aug 15;64(16):5767-74.
Title: A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase.
Author: Myzak, Melinda C|Karplus, P Andrew|Chung, Fung-Lung|Dashwood, Roderick H
PMID: 15313918
Journal: Am J Physiol Cell Physiol. 2004 Dec;287(6):C1541-6. Epub 2004 Aug 18.
Title: Programmed cell death protein 4 suppresses CDK1/cdc2 via induction of p21(Waf1/Cip1).
Author: Goke, R|Barth, P|Schmidt, A|Samans, B|Lankat-Buttgereit, B
PMID: 15317660
Journal: Radiat Res. 2004 Sep;162(3):270-86.
Title: Computerized video time lapse study of cell cycle delay and arrest, mitotic catastrophe, apoptosis and clonogenic survival in irradiated 14-3-3sigma and CDKN1A (p21) knockout cell lines.
Author: Chu, Kenneth|Teele, Noella|Dewey, Michael W|Albright, Norman|Dewey, William C
PMID: 15332997
Journal: J Cancer Res Clin Oncol. 2004 Dec;130(12):695-703. Epub 2004 Aug 31.
Title: Reduced levels of the adenomatous polyposis coli (APC) protein are associated with ceramide-induced apoptosis of colon cancer cells.
Author: Jaiswal, Aruna S|Narayan, Satya
PMID: 15340841
Journal: Cancer Res. 2004 Sep 1;64(17):6296-303.
Title: P21Cip1 is a critical mediator of the cytotoxic action of thymidylate synthase inhibitors in colorectal carcinoma cells.
Author: Geller, James I|Szekely-Szucs, Kinga|Petak, Istvan|Doyle, Belinda|Houghton, Janet A
PMID: 15342418
Journal: Biochem Biophys Res Commun. 2004 Nov 12;324(2):878-86.
Title: Cell cycle-related signaling pathways modulated by peripheral benzodiazepine receptor ligands in colorectal cancer cells.
Author: Maaser, Kerstin|Sutter, Andreas P|Krahn, Antje|Hopfner, Michael|Grabowski, Patricia|Scherubl, Hans
PMID: 15474510
Journal: Chem Biol. 2004 Oct;11(10):1455-63.
Title: A new curcumin derivative, HBC, interferes with the cell cycle progression of colon cancer cells via antagonization of the Ca2+/calmodulin function.
Author: Shim, Joong Sup|Lee, Jiyong|Park, Hyun-Ju|Park, So-Jung|Kwon, Ho Jeong
PMID: 15489172
Journal: World J Gastroenterol. 2004 Dec 1;10(23):3441-54.
Title: Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis.
Author: Xu, Xiao-Li|Yu, Jian|Zhang, Hong-Yu|Sun, Meng-Hong|Gu, Jun|Du, Xiang|Shi, Da-Ren|Wang, Peng|Yang, Zhen-Hua|Zhu, Jing-De
PMID: 15526363
Journal: Clin Cancer Res. 2004 Nov 15;10(22):7727-37.
Title: Regression of mouse prostatic intraepithelial neoplasia by nonsteroidal anti-inflammatory drugs in the transgenic adenocarcinoma mouse prostate model.
Author: Narayanan, Bhagavathi A|Narayanan, Narayanan K|Pittman, Brian|Reddy, Bandaru S
PMID: 15570007
Journal: Nutr Cancer. 2004;50(1):71-9.
Title: Conjugated docosahexaenoic acid is a potent inducer of cell cycle arrest and apoptosis and inhibits growth of colo 201 human colon cancer cells.
Author: Danbara, Naoyuki|Yuri, Takashi|Tsujita-Kyutoku, Miki|Sato, Mutsuya|Senzaki, Hideto|Takada, Hideho|Hada, Takahiko|Miyazawa, Teruo|Okazaki, Kazuichi|Tsubura, Airo
PMID: 15572300
Journal: J Cell Mol Med. 2004 Oct-Dec;8(4):563-9.
Title: PKCdelta requires p53 for suppression of the transformed phenotype in human colon cancer cells.
Author: Perletti, Gianpaolo|Marras, Emanuela|Osti, Daniela|Felici, Lara|Zaro, Sabrina|de Eguileor, Magda
PMID: 15601585
Journal: Cancer Res. 2004 Dec 15;64(24):9086-92.
Title: Tetrandrine induces early G1 arrest in human colon carcinoma cells by down-regulating the activity and inducing the degradation of G1-S-specific cyclin-dependent kinases and by inducing p53 and p21Cip1.
Author: Meng, Ling-Hua|Zhang, Hongliang|Hayward, Larry|Takemura, Haruyuki|Shao, Rong-Guang|Pommier, Yves
PMID: 15604277
Journal: Exp Mol Med. 2004 Dec 31;36(6):557-62.
Title: p21Cip/WAF1 activation is an important factor for the ERK pathway dependent anti-proliferation of colorectal cancer cells.
Author: Park, Ki Sook|Jeon, Soung Hoo|Oh, Jong Won|Choi, Kang Yell
PMID: 15665589
Journal: Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2004 Jun;29(3):261-5.
Title: [Effects of celecoxib on the proliferation and apoptosis of human colorectal cancer cell line HT-29].
Author: Peng, Jie|Zhang, Gui-Ying|Xiao, Zhi-Qiang
PMID: 16136956
Journal: Int J Cancer. 2005 Jan 1;113(1):42-53.
Title: p21(Waf1/Cip1) and p53 are downstream effectors of protein kinase C delta in tumor suppression and differentiation in human colon cancer cells.
Author: Perletti, Gianpaolo|Marras, Emanuela|Dondi, Davide|Osti, Daniela|Congiu, Terenzio|Ferrarese, Roberto|de Eguileor, Magda|Tashjian, Armen H Jr
PMID: 15386430
Journal: Toxicol Sci. 2005 Jan;83(1):126-35.
Title: Characterization of the N-methoxyindole-3-carbinol (NI3C)--induced cell cycle arrest in human colon cancer cell lines.
Author: Neave, Antje S|Sarup, Sussi M|Seidelin, Michel|Duus, Fritz|Vang, Ole
PMID: 15483186
Journal: J Cell Biochem. 2005 Feb 1;94(2):336-50.
Title: Suppression of cyclic GMP-specific phosphodiesterase 5 promotes apoptosis and inhibits growth in HT29 cells.
Author: Zhu, Bing|Vemavarapu, Lakshmi|Thompson, W Joseph|Strada, Samuel J
PMID: 15526282
Journal: J Pharmacol Exp Ther. 2005 Feb;312(2):525-36. Epub 2004 Nov 16.
Title: 5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms.
Author: Schneider-Stock, Regine|Diab-Assef, Mona|Rohrbeck, Astrid|Foltzer-Jourdainne, Charlotte|Boltze, Carsten|Hartig, Roland|Schonfeld, Peter|Roessner, Albert|Gali-Muhtasib, Hala
PMID: 15547111
Journal: Oncogene. 2005 Feb 17;24(8):1338-47.
Title: Caveolin-1 inhibits cell detachment-induced p53 activation and anoikis by upregulation of insulin-like growth factor-I receptors and signaling.
Author: Ravid, Dana|Maor, Sharon|Werner, Haim|Liscovitch, Mordechai
PMID: 15592498
Journal: Anticancer Drugs. 2005 Feb;16(2):129-36.
Title: The Raf kinase inhibitor BAY 43-9006 reduces cellular uptake of platinum compounds and cytotoxicity in human colorectal carcinoma cell lines.
Author: Heim, Martina|Scharifi, Mariam|Zisowsky, Jochen|Jaehde, Ulrich|Voliotis, Dimitris|Seeber, Siegfried|Strumberg, Dirk
PMID: 15655409
Journal: Cell Death Differ. 2005 Apr;12(4):395-404.
Title: Inhibition of histone deacetylase 2 increases apoptosis and p21Cip1/WAF1 expression, independent of histone deacetylase 1.
Author: Huang, B H|Laban, M|Leung, C H-W|Lee, L|Lee, C K|Salto-Tellez, M|Raju, G C|Hooi, S C
PMID: 15665816
Journal: J Lipid Res. 2005 Aug;46(8):1596-603. Epub 2005 Feb 16.
Title: Histone deacetylase 1: a target of 9-hydroxystearic acid in the inhibition of cell growth in human colon cancer.
Author: Calonghi, Natalia|Cappadone, Concettina|Pagnotta, Eleonora|Boga, Carla|Bertucci, Carlo|Fiori, Jessica|Tasco, Gianluca|Casadio, Rita|Masotti, Lanfranco
PMID: 15716589
Journal: Appl Immunohistochem Mol Morphol. 2005 Mar;13(1):38-44.
Title: The clinical significance of p53, p21, and p27 expressions in rectal carcinoma.
Author: Lebe, Banu|Sarioglu, Sulen|Sokmen, Selman|Ellidokuz, Hulya|Fuzun, Mehmet|Kupelioglu, Ali
PMID: 15722792
Journal: Cancer Chemother Pharmacol. 2005 Jun;55(6):577-83. Epub 2005 Feb 22.
Title: Investigation of the role of Bax, p21/Waf1 and p53 as determinants of cellular responses in HCT116 colorectal cancer cells exposed to the novel cytotoxic ruthenium(II) organometallic agent, RM175.
Author: Hayward, R L|Schornagel, Q C|Tente, R|Macpherson, J S|Aird, R E|Guichard, S|Habtemariam, A|Sadler, P|Jodrell, D I
PMID: 15726367
Journal: Oncogene. 2005 Jun 2;24(24):3964-75.
Title: Aminothiol WR1065 induces differential gene expression in the presence of wild-type p53.
Author: Mann, Kristine|Hainaut, Pierre
PMID: 15750621
Journal: Mol Cancer Ther. 2005 Mar;4(3):487-93.
Title: The conventional nonsteroidal anti-inflammatory drug sulindac sulfide arrests ovarian cancer cell growth via the expression of NAG-1/MIC-1/GDF-15.
Author: Kim, Jong-Sik|Baek, Seung Joon|Sali, Tina|Eling, Thomas E
PMID: 15767558
Journal: World J Gastroenterol. 2005 Mar 21;11(11):1693-6.
Title: Effect of indomethacin on cell cycle proteins in colon cancer cell lines.
Author: Xu, Mei-Hua|Zhang, Gui-Ying
PMID: 15786552
Journal: Am J Pathol. 2005 Apr;166(4):1239-46.
Title: Inactivation of p21WAF1/cip1 enhances intestinal tumor formation in Muc2-/- mice.
Author: Yang, Wancai|Velcich, Anna|Lozonschi, Ioana|Liang, Jiao|Nicholas, Courtney|Zhuang, Min|Bancroft, Laura|Augenlicht, Leonard H
PMID: 15793302
Journal: Nutr Cancer. 2005;51(2):207-17.
Title: Inhibition of the growth of premalignant and malignant human oral cell lines by extracts and components of black raspberries.
Author: Han, ChunHua|Ding, Haiming|Casto, Bruce|Stoner, Gary D|D'Ambrosio, Steven M
PMID: 15860443
Journal: J Cell Physiol. 2005 Oct;205(1):107-13.
Title: Inhibition of colon cancer cell proliferation by the dietary compound conjugated linoleic acid is mediated by the CDK inhibitor p21CIP1/WAF1.
Author: Lim, Do Y|Tyner, Angela L|Park, Jae-Bong|Lee, Jae-Yong|Choi, Yung H|Park, Jung H Y
PMID: 15880444
Journal: Hum Pathol. 2005 Apr;36(4):364-71.
Title: Bax, a predictive marker for therapeutic response to preoperative chemoradiotherapy in patients with rectal carcinoma.
Author: Chang, Hee Jin|Jung, Kyung Hae|Kim, Dae Yong|Jeong, Seung-Yong|Choi, Hyo Seong|Kim, Young Hoon|Sohn, Dae Kyung|Yoo, Byong Chul|Lim, Seok-Byung|Kim, Dae-Hyun|Ahn, Joong-Bae|Kim, Il-Jin|Kim, Jin Man|Yoon, Wan-Hee|Park, Jae-Gahb
PMID: 15891997
Journal: Carcinogenesis. 2005 Sep;26(9):1581-9.
Title: Colon-specific regulation of vitamin D hydroxylases--a possible approach for tumor prevention.
Author: Kallay, Eniko|Bises, Giovanna|Bajna, Erika|Bieglmayer, Christian|Gerdenitsch, Waltraud|Steffan, Ilse|Kato, Shigeaki|Armbrecht, H James|Cross, Heide S
PMID: 15905206
Journal: Biochem Pharmacol. 2005 Jul 15;70(2):287-99.
Title: Tangutorine induces p21 expression and abnormal mitosis in human colon cancer HT-29 cells.
Author: Liu, B P L|Chong, E Y Y|Cheung, F W K|Duan, Jin-Ao|Che, Chun-Tao|Liu, W K
PMID: 15916751
Journal: Food Chem Toxicol. 2005 Oct;43(10):1483-95.
Title: Molecular mechanisms of econazole-induced toxicity on human colon cancer cells: G0/G1 cell cycle arrest and caspase 8-independent apoptotic signaling pathways.
Author: Ho, Yuan-Soon|Wu, Chih-Hsiung|Chou, Hsiao-Min|Wang, Ying-Jan|Tseng, How|Chen, Chien-Ho|Chen, Li-Ching|Lee, Chia-Hwa|Lin, Shyr-Yi
PMID: 15919146
Journal: Exp Cell Res. 2005 Jul 1;307(1):231-46. Epub 2005 Apr 19.
Title: Smad7 induces tumorigenicity by blocking TGF-beta-induced growth inhibition and apoptosis.
Author: Halder, Sunil K|Beauchamp, R Daniel|Datta, Pran K
PMID: 15922743
Journal: Cancer Cell Int. 2005 Jun 1;5(1):18.
Title: Preclinical evaluation of the proteasome inhibitor bortezomib in cancer therapy.
Author: Boccadoro, Mario|Morgan, Gareth|Cavenagh, Jamie
PMID: 15929791
Journal: Clin Cancer Res. 2005 Jun 1;11(11):4234-40.
Title: High thymidylate synthase expression in colorectal cancer with microsatellite instability: implications for chemotherapeutic strategies.
Author: Ricciardiello, Luigi|Ceccarelli, Claudio|Angiolini, Graziella|Pariali, Milena|Chieco, Pasquale|Paterini, Paola|Biasco, Guido|Martinelli, Giuseppe N|Roda, Enrico|Bazzoli, Franco
PMID: 15930362
Journal: Int J Oncol. 2005 Jul;27(1):69-76.
Title: Effects of p21cip1/waf1 overexpression on growth, apoptosis and differentiation in human colon carcinoma cells.
Author: Izawa, Hikaru|Yamamoto, Hirofumi|Damdinsuren, Bazarragchaa|Ikeda, Kimimasa|Tsujie, Masaki|Suzuki, Rei|Kitani, Kotaro|Seki, Yosuke|Hayashi, Taro|Takemasa, Ichiro|Ikeda, Masataka|Ohue, Masayuki|Sekimoto, Mitsugu|Monden, Takushi|Monden, Morito
PMID: 15942645
Journal: Endocr Relat Cancer. 2005 Jun;12(2):455-69.
Title: ERbeta is a potent inhibitor of cell proliferation in the HCT8 human colon cancer cell line through regulation of cell cycle components.
Author: Martineti, Valentina|Picariello, Lucia|Tognarini, Isabella|Carbonell Sala, Silvia|Gozzini, Alessia|Azzari, Chiara|Mavilia, Carmelo|Tanini, Annalisa|Falchetti, Alberto|Fiorelli, Gianna|Tonelli, Francesco|Brandi, Maria Luisa
PMID: 15947116
Journal: Mol Cancer Ther. 2005 Jun;4(6):901-9.
Title: Selective induction of apoptosis in mutant p53 premalignant and malignant cancer cells by PRIMA-1 through the c-Jun-NH2-kinase pathway.
Author: Li, Yin|Mao, Yuehua|Brandt-Rauf, Paul W|Williams, Ann C|Fine, Robert L
PMID: 15956247
Journal: Clin Cancer Res. 2005 Jun 15;11(12):4580-8.
Title: Activation of p53-dependent apoptosis by acute ablation of glycogen synthase kinase-3beta in colorectal cancer cells.
Author: Ghosh, Jagadish C|Altieri, Dario C
PMID: 15958644
Journal: Biochem Biophys Res Commun. 2005 Aug 5;333(3):827-32.
Title: Inhibitory effect of genistein on mouse colon cancer MC-26 cells involved TGF-beta1/Smad pathway.
Author: Yu, Zengli|Tang, Yunan|Hu, Dongsheng|Li, Juan
PMID: 15963949
Journal: J Biol Chem. 2005 Sep 9;280(36):32018-25. Epub 2005 Jul 6.
Title: Cyclin-dependent kinase inhibitors uncouple cell cycle progression from mitochondrial apoptotic functions in DNA-damaged cancer cells.
Author: Le, Hong-Van|Minn, Andy J|Massague, Joan
PMID: 16002406
Journal: J Nutr. 2005 Aug;135(8):1865-72.
Title: Transcriptome analysis of human colon Caco-2 cells exposed to sulforaphane.
Author: Traka, Maria|Gasper, Amy V|Smith, Julie A|Hawkey, Chris J|Bao, Yongping|Mithen, Richard F
PMID: 16046710
Journal: Mol Cell Biol. 2005 Sep;25(17):7758-69.
Title: Manganese superoxide dismutase induces p53-dependent senescence in colorectal cancer cells.
Author: Behrend, Lars|Mohr, Andrea|Dick, Tatjana|Zwacka, Ralf M
PMID: 16107721
Journal: Exp Cell Res. 2005 Oct 15;310(1):237-47.
Title: Radiation response and cell cycle regulation of p53 rescued malignant keratinocytes.
Author: Niemantsverdriet, Maarten|Jongmans, Wim|Backendorf, Claude
PMID: 16120440
Journal: Life Sci. 2005 Nov 26;78(2):121-7.
Title: Non-apoptotic concentrations of prodigiosin (H+/Cl- symporter) inhibit the acidification of lysosomes and induce cell cycle blockage in colon cancer cells.
Author: Castillo-Avila, Wilmar|Abal, Miguel|Robine, Sylvie|Perez-Tomas, Ricardo
PMID: 16126233
Journal: Am J Physiol Gastrointest Liver Physiol. 2005 Oct;289(4):G696-703.
Title: The histone deacetylase inhibitor butyrate downregulates cyclin B1 gene expression via a p21/WAF-1-dependent mechanism in human colon cancer cells.
Author: Archer, Sonia Y|Johnson, Jennifer|Kim, Hyun-Ju|Ma, Qing|Mou, Huizhong|Daesety, Vishnuvardhan|Meng, Shufen|Hodin, Richard A
PMID: 16160080
Journal: Clin Cancer Res. 2005 Sep 15;11(18):6650-6.
Title: Molecular alterations in tumors and response to combination chemotherapy with gefitinib for advanced colorectal cancer.
Author: Ogino, Shuji|Meyerhardt, Jeffrey A|Cantor, Mami|Brahmandam, Mohan|Clark, Jeffrey W|Namgyal, Chungdak|Kawasaki, Takako|Kinsella, Kate|Michelini, Ann L|Enzinger, Peter C|Kulke, Matthew H|Ryan, David P|Loda, Massimo|Fuchs, Charles S
PMID: 16166444
Journal: Mol Cancer Res. 2005 Sep;3(9):511-7.
Title: Overexpression of 15-lipoxygenase-1 induces growth arrest through phosphorylation of p53 in human colorectal cancer cells.
Author: Kim, Jong-Sik|Baek, Seung Joon|Bottone, Frank G Jr|Sali, Tina|Eling, Thomas E
PMID: 16179498
Journal: Am J Pathol. 2005 Oct;167(4):969-80.
Title: Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines: inhibition of JAK3/STAT3 signaling induces apoptosis and cell cycle arrest of colon carcinoma cells.
Author: Lin, Quan|Lai, Raymond|Chirieac, Lucian R|Li, Changping|Thomazy, Vilmos A|Grammatikakis, Ioannis|Rassidakis, George Z|Zhang, Wei|Fujio, Yasushi|Kunisada, Keita|Hamilton, Stanley R|Amin, Hesham M
PMID: 16192633
Journal: Hepatogastroenterology. 2005 Sep-Oct;52(65):1421-6.
Title: Venous invasion and down-regulation of p21(WAF1/CIP1) are associated with metastasis in colorectal carcinomas.
Author: Mitomi, Hiroyuki|Mori, Akio|Kanazawa, Hideki|Nishiyama, Yasuhiko|Ihara, Atsushi|Otani, Yoshimasa|Sada, Miwa|Kobayashi, Kiyonori|Igarashi, Masahiro
PMID: 16201087
Journal: Int J Oncol. 2005 Nov;27(5):1391-9.
Title: Indole-3-carbinol inhibits the growth of human colon carcinoma cells but enhances the tumor multiplicity and volume of azoxymethane-induced rat colon carcinogenesis.
Author: Suzui, Masumi|Inamine, Morihiko|Kaneshiro, Tatsuya|Morioka, Takamitsu|Yoshimi, Naoki|Suzuki, Rikako|Kohno, Hiroyuki|Tanaka, Takuji
PMID: 16211236
Journal: Mol Carcinog. 2005 Dec;44(4):293-9.
Title: Artepillin C in Brazilian propolis induces G(0)/G(1) arrest via stimulation of Cip1/p21 expression in human colon cancer cells.
Author: Shimizu, Kazuo|Das, Swadesh K|Hashimoto, Takashi|Sowa, Yoshihiro|Yoshida, Tatsushi|Sakai, Toshiyuki|Matsuura, Yukinaga|Kanazawa, Kazuki
PMID: 16224795
Journal: Biochem Biophys Res Commun. 2005 Dec 2;337(4):1176-84. Epub 2005 Oct 6.
Title: Proteomic analysis of human O6-methylguanine-DNA methyltransferase by affinity chromatography and tandem mass spectrometry.
Author: Niture, Suryakant K|Doneanu, Catalin E|Velu, Chinavenmeni S|Bailey, Nathan I|Srivenugopal, Kalkunte S
PMID: 16226712
Journal: Mol Cancer Ther. 2005 Oct;4(10):1585-94.
Title: Role of p21waf1/cip1 in effects of oxaliplatin in colorectal cancer cells.
Author: Hata, Taishi|Yamamoto, Hirofumi|Ngan, Chew Yee|Koi, Minoru|Takagi, Akimitsu|Damdinsuren, Bazarragchaa|Yasui, Masayoshi|Fujie, Yujiro|Matsuzaki, Takeshi|Hemmi, Hiromichi|Xu, Xundi|Kitani, Kotaro|Seki, Yosuke|Takemasa, Ichiro|Ikeda, Masataka|Sekimoto, Mitsu
PMID: 16227409
Journal: Biochim Biophys Acta. 2005 Nov 30;1726(3):328-35.
Title: Fucoxanthin induces cell cycle arrest at G0/G1 phase in human colon carcinoma cells through up-regulation of p21WAF1/Cip1.
Author: Das, Swadesh K|Hashimoto, Takashi|Shimizu, Kazuo|Yoshida, Tatsushi|Sakai, Toshiyuki|Sowa, Yoshihiro|Komoto, Akitoshi|Kanazawa, Kazuki
PMID: 16236452
Journal: J Nutr. 2005 Nov;135(11):2710-4.
Title: Dietary components modify gene expression: implications for carcinogenesis.
Author: Yang, Kan|Yang, Wancai|Mariadason, John|Velcich, Anna|Lipkin, Martin|Augenlicht, Leonard
PMID: 16251635
Journal: J Nutr. 2005 Dec;135(12):2884-90.
Title: Fisetin inhibits the activities of cyclin-dependent kinases leading to cell cycle arrest in HT-29 human colon cancer cells.
Author: Lu, Xianghua|Jung, Jae in|Cho, Han Jin|Lim, Do Young|Lee, Hyun Sook|Chun, Hyang Sook|Kwon, Dae Young|Park, Jung Han Yoon
PMID: 16317137
Journal: Cancer Chemother Pharmacol. 2006 Feb;57(3):317-27. Epub 2005 Sep 17.
Title: p53-independent G1 cell cycle arrest of human colon carcinoma cells HT-29 by sulforaphane is associated with induction of p21CIP1 and inhibition of expression of cyclin D1.
Author: Shen, Guoxiang|Xu, Changjiang|Chen, Chi|Hebbar, Vidya|Kong, Ah-Ng Tony
PMID: 16170570
Journal: Biochim Biophys Acta. 2006 Jan;1765(1):67-73. Epub 2005 Oct 6.
Title: CtIP, a candidate tumor susceptibility gene is a team player with luminaries.
Author: Chinnadurai, G
PMID: 16249056
Journal: Carcinogenesis. 2006 Apr;27(4):811-9. Epub 2005 Nov 9.
Title: Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells.
Author: Myzak, Melinda C|Hardin, Karin|Wang, Rong|Dashwood, Roderick H|Ho, Emily
PMID: 16280330
Journal: Genome Res. 2006 Feb;16(2):282-9.
Title: Multiplexed profiling of candidate genes for CpG island methylation status using a flexible PCR/LDR/Universal Array assay.
Author: Cheng, Yu-Wei|Shawber, Carrie|Notterman, Dan|Paty, Philip|Barany, Francis
PMID: 16369045
Journal: FASEB J. 2006 Mar;20(3):506-8. Epub 2006 Jan 11.
Title: Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice.
Author: Myzak, Melinda C|Dashwood, W Mohaiza|Orner, Gayle A|Ho, Emily|Dashwood, Roderick H
PMID: 16407454
Journal: Oncogene. 2006 May 11;25(20):2839-49.
Title: p21CDKN1A allows the repair of replication-mediated DNA double-strand breaks induced by topoisomerase I and is inactivated by the checkpoint kinase inhibitor 7-hydroxystaurosporine.
Author: Furuta, T|Hayward, R L|Meng, L-H|Takemura, H|Aune, G J|Bonner, W M|Aladjem, M I|Kohn, K W|Pommier, Y
PMID: 16407843
Journal: Oncogene. 2006 May 25;25(22):3123-38.
Title: Protein kinase C delta inhibits Caco-2 cell proliferation by selective changes in cell cycle and cell death regulators.
Author: Cerda, S R|Mustafi, R|Little, H|Cohen, G|Khare, S|Moore, C|Majumder, P|Bissonnette, M
PMID: 16434969
Journal: Int J Oncol. 2006 Apr;28(4):1003-12.
Title: The antitumor effect of a novel differentiation inducer, 2, 2-Bis (4-(4-amino-3-hydroxyphenoxy) phenyl) adamantane (DPA), in combinatory therapy on human colon cancer.
Author: Wang, Jane-Jen|Lee, Jen-Yi|Chen, Yu-Chen|Chern, Yaw-Terng|Chi, Chin-Wen
PMID: 16525652
Journal: J Nutr. 2006 Apr;136(4):893-8.
Title: Trans-10,cis-12, not cis-9,trans-11, conjugated linoleic acid inhibits G1-S progression in HT-29 human colon cancer cells.
Author: Cho, Han Jin|Kim, Eun Ji|Lim, Soon Sung|Kim, Mi Kyung|Sung, Mi-Kyung|Kim, Jong-Sang|Park, Jung Han Yoon
PMID: 16549447
Journal: Glycobiology. 2006 Jul;16(7):573-83. Epub 2006 Mar 30.
Title: Ganglioside GM3 modulates tumor suppressor PTEN-mediated cell cycle progression--transcriptional induction of p21(WAF1) and p27(kip1) by inhibition of PI-3K/AKT pathway.
Author: Choi, Hee-Jung|Chung, Tae-Wook|Kang, Sung-Koo|Lee, Young-Choon|Ko, Jeong-Heon|Kim, Jong-Guk|Kim, Cheorl-Ho
PMID: 16574813
Journal: Int J Oncol. 2006 May;28(5):1193-9.
Title: Acyclic retinoid, a novel synthetic retinoid, induces growth inhibition, apoptosis, and changes in mRNA expression of cell cycle- and differentiation-related molecules in human colon carcinoma cells.
Author: Suzui, Masumi|Sunagawa, Nao|Chiba, Itaru|Moriwaki, Hisataka|Yoshimi, Naoki
PMID: 16596235
Journal: Oncogene. 2006 Sep 7;25(40):5527-36. Epub 2006 Apr 17.
Title: Deletion of the carcinoembryonic antigen-related cell adhesion molecule 1 (Ceacam1) gene contributes to colon tumor progression in a murine model of carcinogenesis.
Author: Leung, N|Turbide, C|Olson, M|Marcus, V|Jothy, S|Beauchemin, N
PMID: 16619040
Journal: Mol Cancer Ther. 2006 Apr;5(4):893-902.
Title: Methoxyamine potentiates iododeoxyuridine-induced radiosensitization by altering cell cycle kinetics and enhancing senescence.
Author: Yan, Tao|Seo, Yuji|Schupp, Jane E|Zeng, Xuehuo|Desai, Anand B|Kinsella, Timothy J
PMID: 16648559
Journal: BMC Cancer. 2006 May 10;6:124.
Title: Genetic dissection of apoptosis and cell cycle control in response of colorectal cancer treated with preoperative radiochemotherapy.
Author: Sturm, Isrid|Rau, Beate|Schlag, Peter M|Wust, Peter|Hildebrandt, Bert|Riess, Hanno|Hauptmann, Steffen|Dorken, Bernd|Daniel, Peter T
PMID: 16686938
Journal: Toxicology. 2006 Jun 1;223(1-2):136-43.
Title: Cantharidin-induced cytotoxicity and cyclooxygenase 2 expression in human bladder carcinoma cell line.
Author: Huan, Steven Kuan-Hua|Lee, Hao-Hsien|Liu, Der-Zen|Wu, Chien-Chih|Wang, Ching-Chiung
PMID: 16697099
Journal: Int J Biochem Cell Biol. 2006;38(9):1510-7. Epub 2006 Apr 6.
Title: Heme oxygenase-1 inhibits apoptosis in Caco-2 cells via activation of Akt pathway.
Author: Busserolles, Jerome|Megias, Javier|Terencio, Maria Carmen|Alcaraz, Maria Jose
PMID: 16697692
Journal: Mol Cancer. 2006 May 18;5:20.
Title: Cellular response to 5-fluorouracil (5-FU) in 5-FU-resistant colon cancer cell lines during treatment and recovery.
Author: De Angelis, Paula M|Svendsrud, Debbie H|Kravik, Katherine L|Stokke, Trond
PMID: 16709241
Journal: Acta Biochim Pol. 2006;53(2):349-56. Epub 2006 May 30.
Title: Quantitative analysis of the level of p53 and p21(WAF1) mRNA in human colon cancer HT-29 cells treated with inositol hexaphosphate.
Author: Weglarz, Ludmila|Molin, Izabela|Orchel, Arkadiusz|Parfiniewicz, Beata|Dzierzewicz, Zofia
PMID: 16733561
Journal: Br J Pharmacol. 2006 Aug;148(8):1099-107.
Title: Acetyl-keto-beta-boswellic acid inhibits cellular proliferation through a p21-dependent pathway in colon cancer cells.
Author: Liu, Jian-Jun|Huang, Baohua|Hooi, Shing Chuan
PMID: 16783403
Journal: Mol Cancer Ther. 2006 Jun;5(6):1459-66.
Title: Beta-escin inhibits colonic aberrant crypt foci formation in rats and regulates the cell cycle growth by inducing p21(waf1/cip1) in colon cancer cells.
Author: Patlolla, Jagan M R|Raju, Jayadev|Swamy, Malisetty V|Rao, Chinthalapally V
PMID: 16818504
Journal: Exp Mol Med. 2006 Jun 30;38(3):325-31.
Title: Role of p21CIP1 as a determinant of SC-560 response in human HCT116 colon carcinoma cells.
Author: Lee, Eunmyong|Choi, Moon Kyung|Han, Inn Oc|Lim, Soo Jeong
PMID: 16819292
Journal: Chin J Physiol. 2006 Apr 30;49(2):110-6.
Title: Apoptotic effects of over-expressed estrogen receptor-beta on LoVo colon cancer cell is mediated by p53 signalings in a ligand-dependent manner.
Author: Hsu, Hsi-Hsien|Cheng, Sue-Fei|Wu, Cheng-Chung|Chu, Chun-Hsien|Weng, Yi-Jiun|Lin, Chung-Sheng|Lee, Shin-Da|Wu, Hung-Chien|Huang, Chih-Yang|Kuo, Wei-Wen
PMID: 16830793
Journal: Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):11003-8.
Title: Small-molecule modulators of p53 family signaling and antitumor effects in p53-deficient human colon tumor xenografts.
Author: Wang, Wenge|Kim, Seok-Hyun|El-Deiry, Wafik S
PMID: 16835297
Journal: J Pathol. 2006 Oct;210(2):147-54.
Title: Down-regulation of p21 (CDKN1A/CIP1) is inversely associated with microsatellite instability and CpG island methylator phenotype (CIMP) in colorectal cancer.
Author: Ogino, S|Kawasaki, T|Kirkner, G J|Ogawa, A|Dorfman, I|Loda, M|Fuchs, C S
PMID: 16850502
Journal: Planta Med. 2006 Aug;72(10):917-23.
Title: Inhibition of colon cancer (HT-29) cell proliferation by a triterpenoid isolated from Azadirachta indica is accompanied by cell cycle arrest and up-regulation of p21.
Author: Roy, Molay Kumar|Kobori, Masuko|Takenaka, Makiko|Nakahara, Kazuhiko|Shinmoto, Hiroshi|Tsushida, Tojiro
PMID: 16858664
Journal: Free Radic Biol Med. 2006 Aug 15;41(4):601-9.
Title: p21(Cip1/Waf1/Sdi1) protects against hyperoxia by maintaining expression of Bcl-X(L).
Author: Staversky, Rhonda J|Vitiello, Peter F|Gehen, Sean C|Helt, Christopher E|Rahman, Arshad|Keng, Peter C|O'Reilly, Michael A
PMID: 16863993
Journal: Cancer Res. 2006 Aug 1;66(15):7621-9.
Title: In vivo biological activity of the histone deacetylase inhibitor LAQ824 is detectable with 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography.
Author: Leyton, Julius|Alao, John P|Da Costa, Marco|Stavropoulou, Alexandra V|Latigo, John R|Perumal, Meg|Pillai, Radhakrishna|He, Qimin|Atadja, Peter|Lam, Eric W-F|Workman, Paul|Vigushin, David M|Aboagye, Eric O
PMID: 16885362
Journal: Mol Cell Biochem. 2006 Oct;291(1-2):139-44.
Title: Requirement for pre-existing of p21 to prevent doxorubicin-induced apoptosis through inhibition of caspase-3 activation.
Author: Tang, J J|Shen, C|Lu, Y J
PMID: 16909308
Journal: Gastroenterology. 2006 Sep;131(3):841-52.
Title: Recruitment of ataxia-telangiectasia mutated to the p21(waf1) promoter by ZBP-89 plays a role in mucosal protection.
Author: Bai, Longchuan|Kao, John Y|Law, David J|Merchant, Juanita L
PMID: 16952553
Journal: J Agric Food Chem. 2006 Oct 4;54(20):7503-7.
Title: Diallyl disulfide increases CDKN1A promoter-associated histone acetylation in human colon tumor cell lines.
Author: Druesne-Pecollo, Nathalie|Pagniez, Anthony|Thomas, Muriel|Cherbuy, Claire|Duee, Pierre-Henri|Martel, Paule|Chaumontet, Catherine
PMID: 17002414
Journal: World J Gastroenterol. 2006 Sep 21;12(35):5635-43.
Title: Tyrosine kinase of insulin-like growth factor receptor as target for novel treatment and prevention strategies of colorectal cancer.
Author: Hopfner, Michael|Sutter, Andreas P|Huether, Alexander|Baradari, Viola|Scherubl, Hans
PMID: 17007015
Journal: Clin Cancer Res. 2006 Oct 15;12(20 Pt 1):6194-202.
Title: Grape seed extract inhibits in vitro and in vivo growth of human colorectal carcinoma cells.
Author: Kaur, Manjinder|Singh, Rana P|Gu, Mallikarjuna|Agarwal, Rajesh|Agarwal, Chapla
PMID: 17062697
Journal: World J Gastroenterol. 2006 Dec 7;12(45):7263-70.
Title: Effect of ligand troglitazone on peroxisome proliferator-activated receptor gamma expression and cellular growth in human colon cancer cells.
Author: Ming, Mei|Yu, Jie-Ping|Meng, Xiang-Zhi|Zhou, Yan-Hong|Yu, Hong-Gang|Luo, He-Sheng
PMID: 17143939
Journal: Cancer Res. 2006 Dec 1;66(23):11254-62.
Title: p21 blocks irradiation-induced apoptosis downstream of mitochondria by inhibition of cyclin-dependent kinase-mediated caspase-9 activation.
Author: Sohn, Dennis|Essmann, Frank|Schulze-Osthoff, Klaus|Janicke, Reiner U
PMID: 17145870
Journal: Curr Cancer Drug Targets. 2006 Dec;6(8):681-9.
Title: Modulation of the cell cycle and induction of apoptosis in human cancer cells by synthetic bile acids.
Author: Kim, Nam Deuk|Im, Eunok|Yoo, Young Hyun|Choi, Yung Hyun
PMID: 17168673
Journal: Mol Cancer Ther. 2006 Dec;5(12):3222-31.
Title: Tautomycetin inhibits growth of colorectal cancer cells through p21cip/WAF1 induction via the extracellular signal-regulated kinase pathway.
Author: Lee, Joon-Hee|Lee, Jung-Soo|Kim, Sung-Eun|Moon, Byoung-San|Kim, Yong-Chul|Lee, Seung-Kyou|Lee, Sang-Kyou|Choi, Kang-Yell
PMID: 17172426
Journal: Zhonghua Zhong Liu Za Zhi. 2006 Aug;28(8):564-7.
Title: [The effect of PKC-delta inhibitor Rottlerin on human colon cancer cell line SW1116 and its mechanism].
Author: Chen, Zhao-fei|Fang, Jing-yuan|Weng, Yu-rong|Sun, Dan-feng|Wang, Xia|Lu, Rong
PMID: 17236547
Journal: Am J Physiol Gastrointest Liver Physiol. 2007 Jan;292(1):G66-75.
Title: Induction of cell cycle arrest and apoptosis in HT-29 human colon cancer cells by the dietary compound luteolin.
Author: Lim, Do Y|Jeong, Yoonhwa|Tyner, Angela L|Park, Jung H Y
PMID: 16901994
Journal: Oncogene. 2007 Apr 5;26(16):2365-73. Epub 2006 Oct 2.
Title: Kruppel-like factor 4 exhibits antiapoptotic activity following gamma-radiation-induced DNA damage.
Author: Ghaleb, A M|Katz, J P|Kaestner, K H|Du, J X|Yang, V W
PMID: 17016435
Journal: Mod Pathol. 2007 Jan;20(1):15-22. Epub 2006 Nov 3.
Title: Loss of nuclear p27 (CDKN1B/KIP1) in colorectal cancer is correlated with microsatellite instability and CIMP.
Author: Ogino, Shuji|Kawasaki, Takako|Kirkner, Gregory J|Yamaji, Taiki|Loda, Massimo|Fuchs, Charles S
PMID: 17086168
Journal: Cancer Biol Ther. 2007 Feb;6(2):160-9. Epub 2007 Feb 5.
Title: Lack of p53 augments thymoquinone-induced apoptosis and caspase activation in human osteosarcoma cells.
Author: Roepke, Martin|Diestel, Antje|Bajbouj, Khuloud|Walluscheck, Diana|Schonfeld, Peter|Roessner, Albert|Schneider-Stock, Regine|Gali-Muhtasib, Hala
PMID: 17218778
Journal: J Agric Food Chem. 2007 Feb 21;55(4):1156-63. Epub 2007 Jan 23.
Title: Berry phenolic extracts modulate the expression of p21(WAF1) and Bax but not Bcl-2 in HT-29 colon cancer cells.
Author: Wu, Quoc K|Koponen, Jani M|Mykkanen, Hannu M|Torronen, A Riitta
PMID: 17243699
Journal: FEBS Lett. 2007 Mar 6;581(5):865-71.
Title: Surfactin from Bacillus subtilis displays anti-proliferative effect via apoptosis induction, cell cycle arrest and survival signaling suppression.
Author: Kim, Seo-Young|Kim, Joo Young|Kim, Seol-Hee|Bae, Hyun Jin|Yi, Hwaseon|Yoon, Sang Hong|Koo, Bon Sung|Kwon, Moosik|Cho, Jae Youl|Lee, Choong-Eun|Hong, Sungyoul
PMID: 17292358
Journal: Eur J Pharmacol. 2007 Apr 10;560(2-3):95-100. Epub 2007 Jan 19.
Title: JNK1 is required for sulindac-mediated inhibition of cell proliferation and induction of apoptosis in vitro and in vivo.
Author: Song, Zibo|Tong, Chang|Liang, Jiao|Dockendorff, Ashley|Huang, Chuanshu|Augenlicht, Leonard H|Yang, Wancai
PMID: 17292881
Journal: J Biol Chem. 2007 Apr 20;282(16):12249-59. Epub 2007 Feb 16.
Title: Inhibition of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway decreases DNA methylation in colon cancer cells.
Author: Lu, Rong|Wang, Xia|Chen, Zhao-Fei|Sun, Dan-Feng|Tian, Xiao-Qing|Fang, Jing-Yuan
PMID: 17307743
Journal: J Ky Med Assoc. 2007 Jan;105(1):18-22.
Title: Genetic markers predictive of response to induction chemoradiotherapy for locally advanced rectal cancers.
Author: Kudrimoti, Mahesh|Lee, Eun Young|Kang, Yuna|Ahmed, Mansoor|Mohiuddin, Mohammed
PMID: 17310874
Journal: Cell Signal. 2007 Jul;19(7):1465-72. Epub 2007 Jan 24.
Title: BMP-induced growth suppression in colon cancer cells is mediated by p21WAF1 stabilization and modulated by RAS/ERK.
Author: Beck, Stayce E|Jung, Barbara H|Del Rosario, Eunice|Gomez, Jessica|Carethers, John M
PMID: 17317101
Journal: Biochem Pharmacol. 2007 Jun 1;73(11):1715-26. Epub 2007 Feb 4.
Title: Inhibition of G1/S transition potentiates oxaliplatin-induced cell death in colon cancer cell lines.
Author: Rakitina, Tatiana V|Vasilevskaya, Irina A|O'Dwyer, Peter J
PMID: 17343830
Journal: Dev Growth Differ. 2007 Apr;49(3):197-204.
Title: TSC-box is essential for the nuclear localization and antiproliferative effect of XTSC-22.
Author: Hashiguchi, Akiko|Hitachi, Keisuke|Inui, Masafumi|Okabayashi, Koji|Asashima, Makoto
PMID: 17394598
Journal: Cancer Detect Prev. 2007;31(2):110-8. Epub 2007 Apr 6.
Title: Inhibition of cell proliferation, induction of apoptosis, reactivation of DLC1, and modulation of other gene expression by dietary flavone in breast cancer cell lines.
Author: Ullmannova, Veronika|Popescu, Nicholas C
PMID: 17418982
Journal: Int J Cancer. 2007 Sep 1;121(5):1138-48.
Title: Distinct pharmacological properties of second generation HDAC inhibitors with the benzamide or hydroxamate head group.
Author: Beckers, Thomas|Burkhardt, Carmen|Wieland, Heike|Gimmnich, Petra|Ciossek, Thomas|Maier, Thomas|Sanders, Karl
PMID: 17455259
Journal: World J Gastroenterol. 2007 Apr 21;13(15):2209-13.
Title: Expression of p21(WAF1) is related to acetylation of histone H3 in total chromatin in human colorectal cancer.
Author: Chen, Ying-Xuan|Fang, Jing-Yuan|Lu, Rong|Qiu, De-Kai
PMID: 17465503
Journal: Oncogene. 2007 Oct 18;26(48):6954-8. Epub 2007 May 7.
Title: p21(Waf1/Cip1/Sdi1) mediates retinoblastoma protein degradation.
Author: Broude, E V|Swift, M E|Vivo, C|Chang, B-D|Davis, B M|Kalurupalle, S|Blagosklonny, M V|Roninson, I B
PMID: 17486059
Journal: Biochem Biophys Res Commun. 2007 Jul 6;358(3):842-7.
Title: Novel small molecule induces p53-dependent apoptosis in human colon cancer cells.
Author: Park, Sang Eun|Min, Yong Ki|Ha, Jae Du|Kim, Bum Tae|Lee, Woo Ghil
PMID: 17509529
Journal: Carcinogenesis. 2007 Oct;28(10):2207-17.
Title: Aspirin blocks proliferation in colon cells by inducing a G1 arrest and apoptosis through activation of the checkpoint kinase ATM.
Author: Luciani, M Gloria|Campregher, Christoph|Gasche, Christoph
PMID: 17510082
Journal: Biochem Biophys Res Commun. 2007 Aug 3;359(3):747-51. Epub 2007 Jun 4.
Title: Development of a new Ca2+/calmodulin antagonist and its anti-proliferative activity against colorectal cancer cells.
Author: Shim, Joong Sup|Lee, Jiyong|Kim, Kyung Noo|Kwon, Ho Jeong
PMID: 17559805
Journal: Cancer Res. 2007 Jun 15;67(12):5622-7.
Title: LKB1 catalytically deficient mutants enhance cyclin D1 expression.
Author: Scott, Kristine D|Nath-Sain, Suchita|Agnew, Meghan D|Marignani, Paola A
PMID: 17575127
Journal: Cell Cycle. 2007 Jun 15;6(12):1468-71. Epub 2007 Apr 12.
Title: p21 (CDKN1A) is a negative regulator of p53 stability.
Author: Broude, Eugenia V|Demidenko, Zoya N|Vivo, Claire|Swift, Mari E|Davis, Brian M|Blagosklonny, Mikhail V|Roninson, Igor B
PMID: 17585201
Journal: Am J Pathol. 2007 Jul;171(1):297-303.
Title: c-Jun NH2-terminal kinase 1 plays a critical role in intestinal homeostasis and tumor suppression.
Author: Tong, Chang|Yin, Zhinan|Song, Zibo|Dockendorff, Ashley|Huang, Chuanshu|Mariadason, John|Flavell, Richard A|Davis, Roger J|Augenlicht, Leonard H|Yang, Wancai
PMID: 17591974
Journal: Cancer Res. 2007 Jul 15;67(14):6987-94.
Title: Histone deacetylase inhibitors enhance lexatumumab-induced apoptosis via a p21Cip1-dependent decrease in survivin levels.
Author: Nawrocki, Steffan T|Carew, Jennifer S|Douglas, Leslie|Cleveland, John L|Humphreys, Robin|Houghton, Janet A
PMID: 17638911
Journal: Cell Oncol. 2007;29(4):301-13.
Title: Cell-cycle and apoptosis regulators (p16INK4A, p21CIP1, beta-catenin, survivin, and hTERT) and morphometry-defined MPECs predict metachronous cancer development in colorectal adenoma patients.
Author: Soreide, Kjetil|Buter, Tirza C E|Janssen, Emiel A|Gudlaugsson, Einar|Skaland, Ivar|Korner, Hartwig|Baak, Jan P A
PMID: 17641414
Journal: Zhonghua Yi Xue Za Zhi. 2007 Apr 10;87(14):982-6.
Title: [Effects of extracellular signal-regulated kinase/mitogen-activated protein kinase signaling pathway activation on proliferation and cell cycle associated genes in human colon cancer cells].
Author: Wang, Xia|Lu, Rong|Fang, Jing-yuan
PMID: 17650425
Journal: Int J Oncol. 2007 Sep;31(3):613-20.
Title: Type I interferon prolongs cell cycle progression via p21WAF1/CIP1 induction in human colon cancer cells.
Author: Katayama, Tomonari|Nakanishi, Kazuaki|Nishihara, Hiroshi|Kamiyama, Naoya|Nakagawa, Takahito|Kamiyama, Toshiya|Iseki, Ken|Tanaka, Shinya|Todo, Satoru
PMID: 17671689
Journal: Cancer Res. 2007 Aug 15;67(16):7572-8.
Title: Involvement of RNA helicases p68 and p72 in colon cancer.
Author: Shin, Sook|Rossow, Kari L|Grande, Joseph P|Janknecht, Ralf
PMID: 17699760
Journal: Int J Oncol. 2007 Oct;31(4):915-22.
Title: The plant alkaloid cryptolepine induces p21WAF1/CIP1 and cell cycle arrest in a human osteosarcoma cell line.
Author: Matsui, Taka-aki|Sowa, Yoshihiro|Murata, Hiroaki|Takagi, Koichi|Nakanishi, Ryoko|Aoki, Shunji|Yoshikawa, Masayuki|Kobayashi, Motomasa|Sakabe, Tomoya|Kubo, Toshikazu|Sakai, Toshiyuki
PMID: 17786325
Journal: Eur J Gastroenterol Hepatol. 2007 Oct;19(10):883-9.
Title: P21WAF1/CIP1 expression in colorectal carcinomas is related to Kras mutations and prognosis.
Author: Mitomi, Hiroyuki|Ohkura, Yasuo|Fukui, Naoshi|Kanazawa, Hideki|Kishimoto, Ichiro|Nakamura, Takatoshi|Yokoyama, Kaoru|Sada, Miwa|Kobayashi, Kiyonori|Tanabe, Satoshi|Saigenji, Katsunori
PMID: 17873613
Journal: Cancer Res. 2007 Oct 15;67(20):9937-44.
Title: Chemoprevention of familial adenomatous polyposis by natural dietary compounds sulforaphane and dibenzoylmethane alone and in combination in ApcMin/+ mouse.
Author: Shen, Guoxiang|Khor, Tin Oo|Hu, Rong|Yu, Siwang|Nair, Sujit|Ho, Chi-Tang|Reddy, Bandaru S|Huang, Mou-Tuan|Newmark, Harold L|Kong, Ah-Ng Tony
PMID: 17942926
Journal: J Surg Res. 2007 Nov;143(1):58-65.
Title: Flavonoid, silibinin, inhibits proliferation and promotes cell-cycle arrest of human colon cancer.
Author: Hogan, Fawn S|Krishnegowda, Naveen K|Mikhailova, Margarita|Kahlenberg, Morton S
PMID: 17950073
Journal: Cell Cycle. 2007 Nov 1;6(21):2594-8.
Title: Stimulus-specific transcriptional regulation within the p53 network.
Author: Donner, Aaron Joseph|Hoover, Jennifer Michelle|Szostek, Stephanie Aspen|Espinosa, Joaquin Maximiliano
PMID: 17957141
Journal: Cancer Res. 2007 Nov 1;67(21):10466-74.
Title: Involvement of sphingosine kinase 2 in p53-independent induction of p21 by the chemotherapeutic drug doxorubicin.
Author: Sankala, Heidi M|Hait, Nitai C|Paugh, Steven W|Shida, Dai|Lepine, Sandrine|Elmore, Lynne W|Dent, Paul|Milstien, Sheldon|Spiegel, Sarah
PMID: 17974990
Journal: Int J Oncol. 2007 Dec;31(6):1391-402.
Title: Differential response of p53 and p21 on HDAC inhibitor-mediated apoptosis in HCT116 colon cancer cells in vitro and in vivo.
Author: Zopf, Steffen|Neureiter, Daniel|Bouralexis, Steve|Abt, Tobias|Glaser, Keith B|Okamoto, Kinya|Ganslmayer, Marion|Hahn, Eckhart G|Herold, Christoph|Ocker, Matthias
PMID: 17982666
Journal: Int J Oncol. 2007 Dec;31(6):1491-500.
Title: Apoptosis, cell cycle progression and gene expression in TP53-depleted HCT116 colon cancer cells in response to short-term 5-fluorouracil treatment.
Author: Adamsen, Birgitte Lid|Kravik, Katherine L|Clausen, Ole P F|De Angelis, Paula M
PMID: 17982676
Journal: Br J Cancer. 2007 Nov 19;97(10):1344-53.
Title: R306465 is a novel potent inhibitor of class I histone deacetylases with broad-spectrum antitumoral activity against solid and haematological malignancies.
Author: Arts, J|Angibaud, P|Marien, A|Floren, W|Janssens, B|King, P|van Dun, J|Janssen, L|Geerts, T|Tuman, R W|Johnson, D L|Andries, L|Jung, M|Janicot, M|van Emelen, K
PMID: 18000499
Journal: Carcinogenesis. 2008 Jan;29(1):202-10.
Title: Identification through microarray gene expression analysis of cellular responses to benzo(a)pyrene and its diol-epoxide that are dependent or independent of p53.
Author: Hockley, Sarah L|Arlt, Volker M|Jahnke, Gunnar|Hartwig, Andrea|Giddings, Ian|Phillips, David H
PMID: 17942461
Journal: DNA Repair (Amst). 2008 Feb 1;7(2):239-52.
Title: Hypersensitivity to chromium-induced DNA damage correlates with constitutive deregulation of upstream p53 kinases in p21-/- HCT116 colon cancer cells.
Author: Hill, Richard|Leidal, Andrew M|Madureira, Patricia A|Gillis, Laura D|Cochrane, Haley K|Waisman, David M|Chiu, Arthur|Lee, Patrick W K
PMID: 18024214
Journal: Int J Cancer. 2008 May 1;122(9):2115-24.
Title: Combination of atorvastatin and celecoxib synergistically induces cell cycle arrest and apoptosis in colon cancer cells.
Author: Xiao, Hang|Zhang, Qiang|Lin, Yong|Reddy, Bandaru S|Yang, Chung S
PMID: 18172863
Journal: Int J Colorectal Dis. 2008 Apr;23(4):389-400.
Title: Metachronous cancer development in patients with sporadic colorectal adenomas-multivariate risk model with independent and combined value of hTERT and survivin.
Author: Soreide, Kjetil|Gudlaugsson, Einar|Skaland, Ivar|Janssen, Emiel A M|Van Diermen, Bianca|Korner, Hartwig|Baak, Jan P A
PMID: 18189140
Journal: Menopause. 2008 May-Jun;15(3):442-53.
Title: Medroxyprogesterone acetate inhibits proliferation of colon cancer cell lines by modulating cell cycle-related protein expression.
Author: Tanaka, Yoshihiro|Kato, Kiyoko|Mibu, Ryuichi|Uchida, Souko|Asanoma, Kazuo|Hashimoto, Kazunori|Nozaki, Masahiro|Wake, Norio
PMID: 18202593
Journal: J Gastroenterol Hepatol. 2008 Jun;23(6):948-53.
Title: Influence of cancer-related gene polymorphisms on clinicopathological features in colorectal cancer.
Author: Yoshiya, Gen|Takahata, Takenori|Hanada, Naoyuki|Suzuki, Kazuhiro|Ishiguro, Atsushi|Saito, Masato|Sasaki, Mutsuo|Fukuda, Shinsaku
PMID: 18205772
Journal: Free Radic Biol Med. 2008 Feb 1;44(3):367-74.
Title: PUMA inactivation protects against oxidative stress through p21/Bcl-XL inhibition of bax death.
Author: Vitiello, Peter F|Staversky, Rhonda J|Keng, Peter C|O'Reilly, Michael A
PMID: 18215742
Journal: Oncogene. 2008 Jun 5;27(25):3615-23.
Title: p21(WAF1/CIP1) induction by 5-azacytosine nucleosides requires DNA damage.
Author: Jiemjit, A|Fandy, T E|Carraway, H|Bailey, K A|Baylin, S|Herman, J G|Gore, S D
PMID: 18223691
Journal: Gut. 2008 Jun;57(6):780-7.
Title: Activated neutrophils induce an hMSH2-dependent G2/M checkpoint arrest and replication errors at a (CA)13-repeat in colon epithelial cells.
Author: Campregher, C|Luciani, M G|Gasche, C
PMID: 18272544
Journal: Eur J Pharmacol. 2008 Mar 31;583(1):26-31.
Title: Sulindac suppresses beta-catenin expression in human cancer cells.
Author: Han, Anjia|Song, Zibo|Tong, Chang|Hu, Dong|Bi, Xiuli|Augenlicht, Leonard H|Yang, Wancai
PMID: 18291362
Journal: Neoplasia. 2008 Mar;10(3):287-97.
Title: Inhibition of JAK1, 2/STAT3 signaling induces apoptosis, cell cycle arrest, and reduces tumor cell invasion in colorectal cancer cells.
Author: Xiong, Hua|Zhang, Zhi-Gang|Tian, Xiao-Qing|Sun, Dan-Feng|Liang, Qin-Chuan|Zhang, Yan-Jie|Lu, Rong|Chen, Ying-Xuan|Fang, Jing-Yuan
PMID: 18320073
Journal: Cancer Biol Ther. 2008 Jun;7(6):864-72. Epub 2008 Mar 6.
Title: A chemotherapy-associated senescence bystander effect in breast cancer cells.
Author: Di, Xu|Bright, Andrew Taylor|Bellott, Ricardo|Gaskins, Elizabeth|Robert, Jacques|Holt, Shawn|Gewirtz, David|Elmore, Lynne
PMID: 18340112
Journal: Clin Cancer Res. 2008 Mar 15;14(6):1877-87.
Title: Ataxia telangiectasia mutated and p21CIP1 modulate cell survival of drug-induced senescent tumor cells: implications for chemotherapy.
Author: Crescenzi, Elvira|Palumbo, Giuseppe|de Boer, Jasper|Brady, Hugh J M
PMID: 18347191
Journal: J Med Chem. 2008 Apr 24;51(8):2447-56.
Title: Polyaminohydroxamic acids and polyaminobenzamides as isoform selective histone deacetylase inhibitors.
Author: Varghese, Sheeba|Senanayake, Thulani|Murray-Stewart, Tracey|Doering, Kim|Fraser, Alison|Casero, Robert A Jr|Woster, Patrick M
PMID: 18348516
Journal: Int J Cancer. 2008 Jun 15;122(12):2665-73.
Title: Src kinase induces tumor formation in the c-SRC C57BL/6 mouse.
Author: Kline, Christina Leah B|Jackson, Rosalind|Engelman, Robert|Pledger, Warren Jack|Yeatman, Timothy J|Irby, Rosalyn B
PMID: 18351644
Journal: Oncol Rep. 2008 Apr;19(4):1061-6.
Title: The topoisomerase II inhibitor, genistein, induces G2/M arrest and apoptosis in human malignant glioma cell lines.
Author: Schmidt, Friederike|Knobbe, Christiane B|Frank, Brigitte|Wolburg, Hartwig|Weller, Michael
PMID: 18357397
Journal: Biochem Pharmacol. 2008 May 15;75(10):2020-33.
Title: Role of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells.
Author: Lee, Dae-Hee|Kim, Clifford|Zhang, Lin|Lee, Yong J
PMID: 18377871
Journal: Br J Pharmacol. 2008 Jun;154(3):632-8.
Title: Bone morphogenetic protein signalling is required for the anti-mitogenic effect of the proteasome inhibitor MG-132 on colon cancer cells.
Author: Wu, W K K|Sung, J J Y|Wu, Y C|Li, Z J|Yu, L|Cho, C H
PMID: 18414391
Journal: J Cell Mol Med. 2008 Apr;12(2):607-21.
Title: Trichostatin A causes p53 to switch oxidative-damaged colorectal cancer cells from cell cycle arrest into apoptosis.
Author: Habold, C|Poehlmann, A|Bajbouj, K|Hartig, R|Korkmaz, K S|Roessner, A|Schneider-Stock, R
PMID: 18419600
Journal: Int J Oncol. 2008 May;32(5):1105-10.
Title: CDK inhibitor enhances the sensitivity to 5-fluorouracil in colorectal cancer cells.
Author: Takagi, Koichi|Sowa, Yoshihiro|Cevik, Ozgur Muhammer|Nakanishi, Ryoko|Sakai, Toshiyuki
PMID: 18425338
Journal: Mol Nutr Food Res. 2008 Nov;52(11):1289-99.
Title: Expression of selenium-binding protein 1 characterizes intestinal cell maturation and predicts survival for patients with colorectal cancer.
Author: Li, Tianhong|Yang, Wancai|Li, Maomi|Byun, Do-Sun|Tong, Chang|Nasser, Shannon|Zhuang, Min|Arango, Diego|Mariadason, John M|Augenlicht, Leonard H
PMID: 18435490
Journal: Mol Cancer Res. 2008 May;6(5):751-9.
Title: BRAF silencing by short hairpin RNA or chemical blockade by PLX4032 leads to different responses in melanoma and thyroid carcinoma cells.
Author: Sala, Elisa|Mologni, Luca|Truffa, Silvia|Gaetano, Carlo|Bollag, Gideon E|Gambacorti-Passerini, Carlo
PMID: 18458053
Journal: Anticancer Res. 2008 Mar-Apr;28(2A):583-92.
Title: Cellular response to irinotecan in colon cancer cell lines showing differential response to 5-fluorouracil.
Author: Haug, Kristiane|Kravik, K Liza|De Angelis, Paula M
PMID: 18506996
Journal: Int J Clin Pharmacol Ther. 2008 May;46(5):226-35.
Title: Mucronulatol from Caribbean propolis exerts cytotoxic effects on human tumor cell lines.
Author: Diaz-Carballo, D|Freista Hler, M|Malak, S|Bardenheuer, W|Reusch, H P
PMID: 18538108
Journal: Carcinogenesis. 2008 Jul;29(7):1435-40.
Title: Genetic deficiency of decorin causes intestinal tumor formation through disruption of intestinal cell maturation.
Author: Bi, Xiuli|Tong, Chang|Dockendorff, Ashley|Bancroft, Laura|Gallagher, Lindsay|Guzman, Grace|Iozzo, Renato V|Augenlicht, Leonard H|Yang, Wancai
PMID: 18550571
Journal: Mol Cancer Ther. 2008 Jun;7(6):1376-85.
Title: Eps8 decreases chemosensitivity and affects survival of cervical cancer patients.
Author: Chen, Yun-Ju|Shen, Meng-Ru|Chen, Yen-Jen|Maa, Ming-Chei|Leu, Tzeng-Horng
PMID: 18566210
Journal: Cancer Res. 2008 Jul 1;68(13):5355-62.
Title: Activation of protein kinase G Increases the expression of p21CIP1, p27KIP1, and histidine triad protein 1 through Sp1.
Author: Cen, Bo|Deguchi, Atsuko|Weinstein, I Bernard
PMID: 18593937
Journal: Chem Biol Interact. 2008 Aug 11;174(3):201-10.
Title: Inhibition of cell-cycle progression in human colorectal carcinoma Lovo cells by andrographolide.
Author: Shi, Ming-Der|Lin, Hui-Hsuan|Lee, Yi-Che|Chao, Jian-Kang|Lin, Rong-An|Chen, Jing-Hsien
PMID: 18619950
Journal: Mol Cancer Ther. 2008 Jul;7(7):1797-806.
Title: Antiproliferative effect of sulindac in colonic neoplasia prevention: role of COOH-terminal Src kinase.
Author: Kunte, Dhananjay P|Wali, Ramesh K|Koetsier, Jennifer L|Roy, Hemant K
PMID: 18644992
Journal: Mol Cancer Ther. 2008 Jul;7(7):2109-20.
Title: 5,5'-Dibromo-bis(3'-indolyl)methane induces Kruppel-like factor 4 and p21 in colon cancer cells.
Author: Cho, Sung Dae|Chintharlapalli, Sudhakar|Abdelrahim, Maen|Papineni, Sabitha|Liu, Shengxi|Guo, Jingjing|Lei, Ping|Abudayyeh, Ala|Safe, Stephen
PMID: 18645021
Journal: Carcinogenesis. 2008 Nov;29(11):2089-95.
Title: S-adenosylhomocysteine hydrolase downregulation contributes to tumorigenesis.
Author: Leal, J F|Ferrer, I|Blanco-Aparicio, C|Hernandez-Losa, J|Ramon Y Cajal, S|Carnero, A|Lleonart, M E
PMID: 18713839
Journal: J Exp Med. 2008 Sep 1;205(9):2163-75.
Title: A critical role for Apc in hematopoietic stem and progenitor cell survival.
Author: Qian, Zhijian|Chen, Lina|Fernald, Anthony A|Williams, Bart O|Le Beau, Michelle M
PMID: 18725524
Journal: Clin Cancer Res. 2008 Sep 1;14(17):5476-83.
Title: Thymidine selectively enhances growth suppressive effects of camptothecin/irinotecan in MSI+ cells and tumors containing a mutation of MRE11.
Author: Rodriguez, Rene|Hansen, Lasse Tengbjerg|Phear, Geraldine|Scorah, Jennifer|Spang-Thomsen, Mogens|Cox, Angela|Helleday, Thomas|Meuth, Mark
PMID: 18765539
Journal: J Mol Endocrinol. 2008 Nov;41(5):389-92.
Title: Essential role of p21/waf1 in the mediation of the anti-proliferative effects of GHRH antagonist JMR-132.
Author: Volakaki, Aspasia-Athina|Lafkas, Daniel|Kassi, Eva|Schally, Andrew V|Papavassiliou, Athanasios G|Kiaris, Hippokratis
PMID: 18765563
Journal: Cancer Lett. 2008 Dec 18;272(2):253-9.
Title: Switch of transforming growth factor beta function from tumor suppression to stimulation in adenomatous polyposis coli (APC) knocked-down human colon carcinoma cells.
Author: Wang, Hongmei|Promkan, Moltira|Liu, Guangming|Chakrabarty, Subhas
PMID: 18774639
Journal: Oncogene. 2008 Dec 4;27(57):7192-200.
Title: Therapeutic targeting of Id2 reduces growth of human colorectal carcinoma in the murine liver.
Author: Gray, M J|Dallas, N A|Van Buren, G|Xia, L|Yang, A D|Somcio, R J|Gaur, P|Mangala, L S|Vivas-Mejia, P E|Fan, F|Sanguino, A M|Gallick, G E|Lopez-Berestein, G|Sood, A K|Ellis, L M
PMID: 18806828
Journal: Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):15046-51.
Title: AP4 encodes a c-MYC-inducible repressor of p21.
Author: Jung, Peter|Menssen, Antje|Mayr, Doris|Hermeking, Heiko
PMID: 18818310
Journal: J Ethnopharmacol. 2008 Dec 8;120(3):394-401.
Title: Ganoderma tsugae extracts inhibit colorectal cancer cell growth via G(2)/M cell cycle arrest.
Author: Hsu, Shih-Chung|Ou, Chien-Chih|Li, Jhy-Wei|Chuang, Tzu-Chao|Kuo, Han-Pon|Liu, Jah-Yao|Chen, Chin-Shiang|Lin, Song-Chow|Su, Ching-Hua|Kao, Ming-Ching
PMID: 18951965
Journal: Int J Oncol. 2008 Dec;33(6):1307-13.
Title: Pleurotus ostreatus inhibits proliferation of human breast and colon cancer cells through p53-dependent as well as p53-independent pathway.
Author: Jedinak, Andrej|Sliva, Daniel
PMID: 19020765
Journal: Cancer Res. 2008 Dec 15;68(24):10094-104.
Title: p53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrest.
Author: Braun, Christian J|Zhang, Xin|Savelyeva, Irina|Wolff, Sonja|Moll, Ute M|Schepeler, Troels|Orntoft, Torben F|Andersen, Claus L|Dobbelstein, Matthias
PMID: 19074875
Journal: Epigenetics. 2008 Nov;3(6):330-5. Epub 2008 Nov 3.
Title: Folic acid and sodium butyrate prevent tumorigenesis in a mouse model of colorectal cancer.
Author: Lu, Rong|Wang, Xia|Sun, Dan-Feng|Tian, Xiao-Qing|Zhao, Shu-Liang|Chen, Ying-Xuan|Fang, Jing-Yuan
PMID: 19098451
Journal: Int J Clin Pract. 2008 Nov;62(11):1736-43.
Title: Expression patterns of cyclins D1, E and cyclin-dependent kinase inhibitors p21waf1/cip1, p27kip1 in colorectal carcinoma: correlation with other cell cycle regulators (pRb, p53 and Ki-67 and PCNA) and clinicopathological features.
Author: Ioachim, E
PMID: 19143860
Journal: BMC Gastroenterol. 2009 May 29;9:39.
Title: Induction of G1 and G2/M cell cycle arrests by the dietary compound 3,3'-diindolylmethane in HT-29 human colon cancer cells.
Author: Choi, Hyun Ju|Lim, Do Young|Park, Jung Han Yoon
PMID: 2670081
Journal: Cancer Lett. 2009 Mar 8;275(1):9-16.
Title: Calcium, calcium-sensing receptor and colon cancer.
Author: Whitfield, James F
PMID: 18725175
Journal: Nutr Cancer. 2009;61(1):137-45.
Title: Involvement of KLF4 in sulforaphane- and iberin-mediated induction of p21(waf1/cip1).
Author: Traka, Maria H|Chambers, Karen F|Lund, Elizabeth K|Goodlad, Robert A|Johnson, Ian T|Mithen, Richard F
PMID: 19116884
Journal: DNA Repair (Amst). 2009 Mar 1;8(3):390-9.
Title: HCT116 cells deficient in p21(Waf1) are hypersensitive to tyrosine kinase inhibitors and adriamycin through a mechanism unrelated to p21 and dependent on p53.
Author: Ferrandiz, Nuria|Martin-Perez, Jorge|Blanco, Rosa|Donertas, Derya|Weber, Axel|Eilers, Martin|Dotto, Paolo|Delgado, M Dolores|Leon, Javier
PMID: 19150257
Journal: Life Sci. 2009 Feb 27;84(9-10):311-20.
Title: Possible involvement of activation of P53/P21 and demethylation of RUNX 3 in the cytotoxicity against Lovo cells induced by 5-Aza-2'-deoxycytidine.
Author: Deng, Tao|Zhang, Yan
PMID: 19159630
Journal: Hum Mutat. 2009 Apr;30(4):661-8.
Title: Genotype and haplotype analysis of cell cycle genes in sporadic colorectal cancer in the Czech Republic.
Author: Polakova, V|Pardini, B|Naccarati, A|Landi, S|Slyskova, J|Novotny, J|Vodickova, L|Bermejo, J L|Hanova, M|Smerhovsky, Z|Tulupova, E|Kumar, R|Hemminki, K|Vodicka, P
PMID: 19224585
Journal: Biochem Biophys Res Commun. 2009 Apr 24;382(1):79-84.
Title: Inhibition of cyclooxygenase-1 lowers proliferation and induces macroautophagy in colon cancer cells.
Author: Wu, William Ka Kei|Sung, Joseph Jao Yiu|Wu, Ya Chun|Li, Hai To|Yu, Le|Li, Zhi Jie|Cho, Chi Hin
PMID: 19258012
Journal: Biochem Biophys Res Commun. 2009 May 1;382(2):451-6.
Title: Inhibition of macroautophagy by bafilomycin A1 lowers proliferation and induces apoptosis in colon cancer cells.
Author: Wu, Ya Chun|Wu, William Ka Kei|Li, Youming|Yu, Le|Li, Zhi Jie|Wong, Clover Ching Man|Li, Hai Tao|Sung, Joseph Jao Yiu|Cho, Chi Hin
PMID: 19289106
Journal: Lab Invest. 2009 Jun;89(6):717-25.
Title: Inhibition of STAT5 induces G1 cell cycle arrest and reduces tumor cell invasion in human colorectal cancer cells.
Author: Xiong, Hua|Su, Wen-Yu|Liang, Qin-Chuan|Zhang, Zhi-Gang|Chen, Hui-Min|Du, Wan|Chen, Ying-Xuan|Fang, Jing-Yuan
PMID: 19290007
Journal: Cell Death Differ. 2009 Sep;16(9):1203-14.
Title: p38alpha blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1alpha- to FoxO-dependent transcription.
Author: Chiacchiera, F|Matrone, A|Ferrari, E|Ingravallo, G|Lo Sasso, G|Murzilli, S|Petruzzelli, M|Salvatore, L|Moschetta, A|Simone, C
PMID: 19343039
Journal: Int J Cancer. 2009 Jul 15;125(2):463-73.
Title: Histone deacetylase inhibitors suppress thymidylate synthase gene expression and synergize with the fluoropyrimidines in colon cancer cells.
Author: Fazzone, William|Wilson, Peter M|Labonte, Melissa J|Lenz, Heinz-Josef|Ladner, Robert D
PMID: 19384949
Journal: Gastroenterology. 2009 Aug;137(2):639-48, 648.e1-9.
Title: ITF-2 is disrupted via allelic loss of chromosome 18q21, and ITF-2B expression is lost at the adenoma-carcinoma transition.
Author: Herbst, Andreas|Bommer, Guido T|Kriegl, Lydia|Jung, Andreas|Behrens, Andrea|Csanadi, Endy|Gerhard, Markus|Bolz, Christian|Riesenberg, Rainer|Zimmermann, Wolfgang|Dietmaier, Wolfgang|Wolf, Isabella|Brabletz, Thomas|Goke, Burkhard|Kolligs, Frank T
PMID: 19394332
Journal: Cancer Gene Ther. 2009 Nov;16(11):810-9.
Title: RNA interference-mediated knockdown of p21(WAF1) enhances anti-tumor cell activity of oncolytic adenoviruses.
Author: Shiina, M|Lacher, M D|Christian, C|Korn, W M
PMID: 19407849
Journal: Cancer Lett. 2009 Sep 28;283(1):108-17.
Title: Growth-inhibitory effects of the astaxanthin-rich alga Haematococcus pluvialis in human colon cancer cells.
Author: Palozza, Paola|Torelli, Cristiana|Boninsegna, Alma|Simone, Rossella|Catalano, Assunta|Mele, Maria Cristina|Picci, Nevio
PMID: 19423215
Journal: Biochem Pharmacol. 2009 Sep 15;78(6):561-72.
Title: Multiple defects in negative regulation of the PKB/Akt pathway sensitise human cancer cells to the antiproliferative effect of non-steroidal anti-inflammatory drugs.
Author: Lincova, Eva|Hampl, Ales|Pernicova, Zuzana|Starsichova, Andrea|Krcmar, Pavel|Machala, Miroslav|Kozubik, Alois|Soucek, Karel
PMID: 19433066
Journal: Biochem Pharmacol. 2009 Sep 1;78(5):486-94.
Title: A novel delta-lactam-based histone deacetylase inhibitor, KBH-A42, induces cell cycle arrest and apoptosis in colon cancer cells.
Author: Kang, Moo Rim|Kang, Jong Soon|Han, Sang-Bae|Kim, Jang Hyun|Kim, Dong-Myung|Lee, Kiho|Lee, Chang Woo|Lee, Ki Hoon|Lee, Chul Ho|Han, Gyoonhee|Kang, Jong Seong|Kim, Hwan Mook|Park, Song-Kyu
PMID: 19445901
Journal: Biochem Pharmacol. 2009 Jul 15;78(2):123-32.
Title: A nuclear budding mechanism in transiently arrested cells generates drug-sensitive and drug-resistant cells.
Author: Mansilla, Sylvia|Bataller, Marc|Portugal, Jose
PMID: 19464429
Journal: BMC Gastroenterol. 2009 May 29;9:39.
Title: Induction of G1 and G2/M cell cycle arrests by the dietary compound 3,3'-diindolylmethane in HT-29 human colon cancer cells.
Author: Choi, Hyun Ju|Lim, Do Young|Park, Jung Han Yoon
PMID: 19480695
Journal: Cancer Lett. 2009 Nov 18;285(1):66-72.
Title: Cyclosporine A inhibits colorectal cancer proliferation probably by regulating expression levels of c-Myc, p21(WAF1/CIP1) and proliferating cell nuclear antigen.
Author: Masuo, Takashige|Okamura, Shinichi|Zhang, Yajing|Mori, Masatomo
PMID: 19481339
Journal: Carcinogenesis. 2009 Aug;30(8):1459-68.
Title: Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer.
Author: Larriba, Maria Jesus|Martin-Villar, Ester|Garcia, Jose Miguel|Pereira, Fabio|Pena, Cristina|de Herreros, Antonio Garcia|Bonilla, Felix|Munoz, Alberto
PMID: 19502595
Journal: Cancer Epidemiol Biomarkers Prev. 2009 Jun;18(6):1849-58.
Title: A cohort study of p27 localization in colon cancer, body mass index, and patient survival.
Author: Ogino, Shuji|Shima, Kaori|Nosho, Katsuhiko|Irahara, Natsumi|Baba, Yoshifumi|Wolpin, Brian M|Giovannucci, Edward L|Meyerhardt, Jeffrey A|Fuchs, Charles S
PMID: 19505918
Journal: Cancer Sci. 2009 Sep;100(9):1585-90.
Title: Downregulation of MSP58 inhibits growth of human colorectal cancer cells via regulation of the cyclin D1-cyclin-dependent kinase 4-p21 pathway.
Author: Shi, Hai|Chen, Sunxiao|Jin, Haifeng|Xu, Chunsheng|Dong, Guanglong|Zhao, Qingchuan|Wang, Weizhong|Zhang, Hongwei|Lin, Wei|Zhang, Jing|Davidovic, Laetitia|Yao, Libo|Fan, Daiming
PMID: 19549253
Journal: Clin Cancer Res. 2009 Jul 1;15(13):4431-8.
Title: A cohort study of cyclin D1 expression and prognosis in 602 colon cancer cases.
Author: Ogino, Shuji|Nosho, Katsuhiko|Irahara, Natsumi|Kure, Shoko|Shima, Kaori|Baba, Yoshifumi|Toyoda, Saori|Chen, Li|Giovannucci, Edward L|Meyerhardt, Jeffrey A|Fuchs, Charles S
PMID: 19549773
Journal: Ai Zheng. 2009 Feb;28(2):138-41. Epub 2009 Feb 15.
Title: Effect of diallyl disulfide on cell cycle arrest of human colon cancer SW480 cells.
Author: Liao, Qian-Jin|Su, Jian|He, Jie|Song, Ying|Tang, Hai-Lin|Su, Qi
PMID: 19550124
Journal: Int J Cancer. 2009 Dec 15;125(12):2802-9.
Title: KLF4-dependent, PPARgamma-induced expression of GPA33 in colon cancer cell lines.
Author: Rageul, Julie|Mottier, Stephanie|Jarry, Anne|Shah, Yatrik|Theoleyre, Sandrine|Masson, Damien|Gonzalez, Frank J|Laboisse, Christian L|Denis, Marc G
PMID: 19551868
Journal: Eur J Cancer. 2009 Sep;45(13):2402-11.
Title: Cell cycle and apoptotic effects of SAHA are regulated by the cellular microenvironment in HCT116 multicellular tumour spheroids.
Author: Lobjois, Valerie|Frongia, Celine|Jozan, Suzanne|Truchet, Isabelle|Valette, Annie
PMID: 19553104
Journal: BMC Cancer. 2009 Jun 26;9:207.
Title: Proneoplastic effects of PGE2 mediated by EP4 receptor in colorectal cancer.
Author: Doherty, Glen A|Byrne, Sinead M|Molloy, Eamonn S|Malhotra, Vikrum|Austin, Sandra C|Kay, Elaine W|Murray, Frank E|Fitzgerald, Desmond J
PMID: 19558693
Journal: Cancer. 2009 Oct 1;115(19):4459-69.
Title: Gold (III) porphyrin complexes induce apoptosis and cell cycle arrest and inhibit tumor growth in colon cancer.
Author: Tu, Shuiping|Wai-Yin Sun, Raymond|Lin, Marie C M|Tao Cui, Jian|Zou, Bing|Gu, Qing|Kung, Hsiang-Fu|Che, Chi-Ming|Wong, Benjamin C Y
PMID: 19572413
Journal: Oncol Rep. 2009 Aug;22(2):349-54.
Title: Growth inhibitory activity of ethanol extracts of Chinese and Brazilian propolis in four human colon carcinoma cell lines.
Author: Ishihara, Masashi|Naoi, Kuniko|Hashita, Masanari|Itoh, Yoshinori|Suzui, Masumi
PMID: 19578776
Journal: Biochem Pharmacol. 2009 Nov 15;78(10):1305-15.
Title: Curcumin derivatives: molecular basis of their anti-cancer activity.
Author: Basile, Valentina|Ferrari, Erika|Lazzari, Sandra|Belluti, Silvia|Pignedoli, Francesca|Imbriano, Carol
PMID: 19580791
Journal: Cancer Res. 2009 Aug 1;69(15):6100-6.
Title: Tumor repressive functions of estrogen receptor beta in SW480 colon cancer cells.
Author: Hartman, Johan|Edvardsson, Karin|Lindberg, Karolina|Zhao, Chunyan|Williams, Cecilia|Strom, Anders|Gustafsson, Jan-Ake
PMID: 19602591
Journal: Biochem Biophys Res Commun. 2009 Oct 2;387(4):736-40.
Title: The transcription factor ITF-2A induces cell cycle arrest via p21(Cip1).
Author: Herbst, Andreas|Helferich, Simone|Behrens, Andrea|Goke, Burkhard|Kolligs, Frank T
PMID: 19635457
Journal: Nat Cell Biol. 2009 Sep;11(9):1135-42.
Title: p53 isoforms Delta133p53 and p53beta are endogenous regulators of replicative cellular senescence.
Author: Fujita, Kaori|Mondal, Abdul M|Horikawa, Izumi|Nguyen, Giang H|Kumamoto, Kensuke|Sohn, Jane J|Bowman, Elise D|Mathe, Ewy A|Schetter, Aaron J|Pine, Sharon R|Ji, Helen|Vojtesek, Borivoj|Bourdon, Jean-Christophe|Lane, David P|Harris, Curtis C
PMID: 19701195
Journal: Cancer Epidemiol Biomarkers Prev. 2009 Sep;18(9):2513-21.
Title: p21 expression in colon cancer and modifying effects of patient age and body mass index on prognosis.
Author: Ogino, Shuji|Nosho, Katsuhiko|Shima, Kaori|Baba, Yoshifumi|Irahara, Natsumi|Kirkner, Gregory J|Hazra, Aditi|De Vivo, Immaculata|Giovannucci, Edward L|Meyerhardt, Jeffrey A|Fuchs, Charles S
PMID: 19723919
Journal: Cell Cycle. 2009 Oct 1;8(19):3157-64. Epub 2009 Oct 3.
Title: Hypoxia-mediated regulation of Cdc25A phosphatase by p21 and miR-21.
Author: de Oliveira, Pierre E Queiroz|Zhang, Lin|Wang, Zhenghe|Lazo, John S
PMID: 19738433
Journal: Cell Cycle. 2009 Oct 1;8(19):3149-56. Epub 2009 Oct 3.
Title: GHRH antagonist causes DNA damage leading to p21 mediated cell cycle arrest and apoptosis in human colon cancer cells.
Author: Hohla, Florian|Buchholz, Stefan|Schally, Andrew V|Seitz, Stefan|Rick, Ferenc G|Szalontay, Luca|Varga, Jozsef L|Zarandi, Marta|Halmos, Gabor|Vidaurre, Irving|Krishan, Awtar|Kurtoglu, Metin|Chandna, Sudhir|Aigner, Elmar|Datz, Christian
PMID: 19755849
Journal: Cancer Res. 2009 Oct 15;69(20):8175-82.
Title: Inhibition of azoxymethane-induced colorectal cancer by CP-31398, a TP53 modulator, alone or in combination with low doses of celecoxib in male F344 rats.
Author: Rao, Chinthalapally V|Steele, Vernon E|Swamy, Malisetty V|Patlolla, Jagan M R|Guruswamy, Suresh|Kopelovich, Levy
PMID: 19826045
Journal: Mol Cells. 2009 Nov 30;28(5):489-94.
Title: The p53-p21(Cip1/WAF1) pathway is necessary for cellular senescence induced by the inhibition of protein kinase CKII in human colon cancer cells.
Author: Kang, Ji-Young|Kim, Jin Joo|Jang, Seok Young|Bae, Young-Seuk
PMID: 19855935
Journal: J Pharmacol Sci. 2009 Nov;111(3):276-84.
Title: Xanthorrhizol, a natural sesquiterpenoid, induces apoptosis and growth arrest in HCT116 human colon cancer cells.
Author: Kang, You-Jin|Park, Kwang-Kyun|Chung, Won-Yoon|Hwang, Jae-Kwan|Lee, Sang Kook
PMID: 19926935
Journal: J Microbiol Biotechnol. 2009 Nov;19(11):1482-9.
Title: Anti-proliferative effect of polysaccharides from Salicornia herbacea on induction of G2/M arrest and apoptosis in human colon cancer cells.
Author: Ryu, Deok-Seon|Kim, Seon-Hee|Lee, Dong-Seok
PMID: 19996705
Journal: J Cell Mol Med. 2009 Sep;13(9B):3668-79.
Title: Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signalling.
Author: Xiong, Hua|Chen, Zhao-Fei|Liang, Qin-Chuan|Du, Wan|Chen, Hui-Min|Su, Wen-Yu|Chen, Guo-Qiang|Han, Ze-Guang|Fang, Jing-Yuan
PMID: 20196786
Journal: Proteomics Clin Appl. 2009 Apr;3(4):423-32.
Title: Identification and validation of calmodulin as a binding protein of an anti-proliferative small molecule 3,4-dihydroisoquinolinium salt.
Author: Jung, Hye Jin|Shim, Joong Sup|Park, Jungchan|Ha, Hyun-Joon|Kim, Jung-Ho|Kim, Joong-Gon|Kim, Nam Doo|Yoon, Jeong Hyeok|Kwon, Ho Jeong
PMID: 21136969
Journal: Int J Cancer. 2010 Feb 1;126(3):631-9.
Title: Vitamin D mediates its action in human colon carcinoma cells in a calcium-sensing receptor-dependent manner: downregulates malignant cell behavior and the expression of thymidylate synthase and survivin and promotes cellular sensitivity to 5-FU.
Author: Liu, Guangming|Hu, Xin|Chakrabarty, Subhas
PMID: 19621386
Journal: Invest New Drugs. 2010 Oct;28(5):575-86.
Title: The induction of senescence-like growth arrest by protein kinase C-activating diterpene esters in solid tumor cells.
Author: Mason, Sharon A|Cozzi, Sarah-Jane|Pierce, Carly J|Pavey, Sandra J|Parsons, Peter G|Boyle, Glen M
PMID: 19636513
Journal: Int J Cancer. 2010 Apr 15;126(8):1838-49.
Title: Restoration of absent in melanoma 2 (AIM2) induces G2/M cell cycle arrest and promotes invasion of colorectal cancer cells.
Author: Patsos, Georgios|Germann, Anja|Gebert, Johannes|Dihlmann, Susanne
PMID: 19795419
Journal: Anat Rec (Hoboken). 2010 Jan;293(1):42-7.
Title: Transforming growth factor-beta suppressed Id-1 Expression in a smad3-dependent manner in LoVo cells.
Author: Song, Hongjiang|Guo, Baoliang|Zhang, Jianguo|Song, Chunfang
PMID: 19798702
Journal: J Neurooncol. 2010 May;97(3):373-82.
Title: p53 Regulates LIF expression in human medulloblastoma cells.
Author: Baxter, Euan W|Milner, Jo
PMID: 19907922
Journal: Carcinogenesis. 2010 May;31(5):880-5.
Title: Differential in vivo mechanism of chemoprevention of tumor formation in azoxymethane/dextran sodium sulfate mice by PEITC and DBM.
Author: Cheung, Ka Lung|Khor, Tin Oo|Huang, Mou-Tuan|Kong, Ah-Ng
PMID: 19959557
Journal: Cancer Lett. 2010 Jun 1;292(1):80-90.
Title: Cellular response and activation of apoptosis by mithramycin SK in p21(WAF1)-deficient HCT116 human colon carcinoma cells.
Author: Bataller, Marc|Mendez, Carmen|Salas, Jose A|Portugal, Jose
PMID: 19962819
Journal: Phytother Res. 2010 Jul;24(7):1019-26.
Title: The ethyl acetate extract of Phellinus linteus grown on germinated brown rice induces G0/G1 cell cycle arrest and apoptosis in human colon carcinoma HT29 cells.
Author: Park, Hye-Jin|Choi, Se Young|Hong, Se Mi|Hwang, Sung Gu|Park, Dong Ki
PMID: 19998418
Journal: Cancer Prev Res (Phila). 2010 Jan;3(1):82-91.
Title: Chemopreventive effects of Frondanol A5, a Cucumaria frondosa extract, against rat colon carcinogenesis and inhibition of human colon cancer cell growth.
Author: Janakiram, Naveena B|Mohammed, Altaf|Zhang, Yuting|Choi, Chang-In|Woodward, Carl|Collin, Peter|Steele, Vernon E|Rao, Chinthalapally V
PMID: 20051375
Journal: Cancer Res. 2010 Jan 15;70(2):792-801.
Title: Matrix metalloproteinase-9 functions as a tumor suppressor in colitis-associated cancer.
Author: Garg, Pallavi|Sarma, Dittakavi|Jeppsson, Sabrina|Patel, Neal R|Gewirtz, Andrew T|Merlin, Didier|Sitaraman, Shanthi V
PMID: 20068187
Journal: Neoplasia. 2010 Jan;12(1):95-102.
Title: Dietary feeding of grape seed extract prevents intestinal tumorigenesis in APCmin/+ mice.
Author: Velmurugan, Balaiya|Singh, Rana P|Kaul, Nidhi|Agarwal, Rajesh|Agarwal, Chapla
PMID: 20072658
Journal: Mol Cancer Ther. 2010 Feb;9(2):450-60.
Title: A novel E1B-55kD-deleted oncolytic adenovirus carrying mutant KRAS-regulated hdm2 transgene exerts specific antitumor efficacy on colorectal cancer cells.
Author: Liu, Chin-Cheng|Liu, Jin-Hwang|Wu, Suh-Chin|Yen, Chueh-Chuan|Chen, Wei-Shone|Tsai, Ying-Chieh
PMID: 20124454
Journal: Br J Pharmacol. 2010 Mar;159(6):1326-38.
Title: Oxaliplatin responses in colorectal cancer cells are modulated by CHK2 kinase inhibitors.
Author: Pires, I M|Ward, T H|Dive, C
PMID: 20128802
Journal: Cancer Res. 2010 Mar 1;70(5):2053-63.
Title: FOXQ1 is overexpressed in colorectal cancer and enhances tumorigenicity and tumor growth.
Author: Kaneda, Hiroyasu|Arao, Tokuzo|Tanaka, Kaoru|Tamura, Daisuke|Aomatsu, Keiichi|Kudo, Kanae|Sakai, Kazuko|De Velasco, Marco A|Matsumoto, Kazuko|Fujita, Yoshihiko|Yamada, Yasuhide|Tsurutani, Junji|Okamoto, Isamu|Nakagawa, Kazuhiko|Nishio, Kazuto
PMID: 20145154
Journal: Cell Biol Int. 2010 Apr 14;34(6):565-72.
Title: Hydrogen sulfide induces human colon cancer cell proliferation: role of Akt, ERK and p21.
Author: Cai, Wen-Jie|Wang, Ming-Jie|Ju, Li-Hua|Wang, Cheng|Zhu, Yi-Chun
PMID: 20184555
Journal: In Vivo. 2010 Mar-Apr;24(2):179-83.
Title: Association between CDKN1A Ser31Arg and C20T gene polymorphisms and colorectal cancer risk and prognosis.
Author: Cacina, Canan|Yaylim-Eraltan, Ilhan|Arikan, Soykan|Saglam, Esra Kaytan|Zeybek, Umit|Isbir, Turgay
PMID: 20363991
Journal: Mol Nutr Food Res. 2010 Jul;54 Suppl 2:S244-52.
Title: Inhibitory effects of 5-hydroxy polymethoxyflavones on colon cancer cells.
Author: Qiu, Peiju|Dong, Ping|Guan, Huashi|Li, Shiming|Ho, Chi-Tang|Pan, Min-Hsiung|McClements, David Julian|Xiao, Hang
PMID: 20397199
Journal: World J Surg Oncol. 2010 Apr 17;8:29.
Title: Advanced moderately differentiated neuroendocrine carcinoma of the rectum with favorable prognosis by postoperative chemoradiation.
Author: Nojima, Hiroyuki|Seike, Kazuhiro|Kosugi, Chihiro|Shida, Takashi|Koda, Keiji|Oda, Kenji|Kamata, Shigeyuki|Ishikura, Hiroshi|Miyazaki, Masaru
PMID: 20398400
Journal: Mol Cancer Ther. 2010 May;9(5):1308-17.
Title: Epithelial-to-mesenchymal transition and oncogenic Ras expression in resistance to the protein kinase Cbeta inhibitor enzastaurin in colon cancer cells.
Author: Serova, Maria|Astorgues-Xerri, Lucile|Bieche, Ivan|Albert, Sebastien|Vidaud, Michel|Benhadji, Karim A|Emami, Shahin|Vidaud, Dominique|Hammel, Pascal|Theou-Anton, Nathalie|Gespach, Christian|Faivre, Sandrine|Raymond, Eric
PMID: 20406951
Journal: J Mol Med (Berl). 2010 Jun;88(6):609-22.
Title: Systematic genetic dissection of p14ARF-mediated mitochondrial cell death signaling reveals a key role for p21CDKN1 and the BH3-only protein Puma/bbc3.
Author: Hemmati, Philipp G|Muer, Annika|Gillissen, Bernd|Overkamp, Tim|Milojkovic, Ana|Wendt, Jana|Dorken, Bernd|Daniel, Peter T
PMID: 20419447
Journal: Naunyn Schmiedebergs Arch Pharmacol. 2010 Jul;382(1):43-50.
Title: 5,5-Diphenyl-2-thiohydantoin-N10 (DPTH-N10) suppresses proliferation of cultured colon cancer cell line COLO-205 by inhibiting DNA synthesis and activating apoptosis.
Author: Lee, Tong-Sheng|Chen, Li-Ching|Liu, Yuan|Wu, Jender|Liang, Yu-Chih|Lee, Wen-Sen
PMID: 20449574
Journal: J Cell Biochem. 2010 Oct 1;111(2):412-24.
Title: Sodium 5,6-benzylidene-L-ascorbate induces oxidative stress, autophagy, and growth arrest in human colon cancer HT-29 cells.
Author: Cheung, F W K|Che, C T|Sakagami, H|Kochi, M|Liu, W K
PMID: 20503249
Journal: Mol Cancer. 2010 May 27;9:125.
Title: Epigenomic diversity of colorectal cancer indicated by LINE-1 methylation in a database of 869 tumors.
Author: Baba, Yoshifumi|Huttenhower, Curtis|Nosho, Katsuhiko|Tanaka, Noriko|Shima, Kaori|Hazra, Aditi|Schernhammer, Eva S|Hunter, David J|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji
PMID: 20507599
Journal: Br J Cancer. 2010 Jun 8;102(12):1753-61.
Title: Pregnane X receptor suppresses proliferation and tumourigenicity of colon cancer cells.
Author: Ouyang, N|Ke, S|Eagleton, N|Xie, Y|Chen, G|Laffins, B|Yao, H|Zhou, B|Tian, Y
PMID: 20531417
Journal: Biometals. 2010 Dec;23(6):1061-73.
Title: Beryllium sulfate induces p21 CDKN1A expression and a senescence-like cell cycle arrest in susceptible cancer cell types.
Author: Gorjala, Priyatham|Gary, Ronald K
PMID: 20549306
Journal: Cancer. 2010 Oct 1;116(19):4474-86.
Title: Expression of p16 in lymph node metastases of adjuvantly treated stage III colorectal cancer patients identifies poor prognostic subgroups: a retrospective analysis of biomarkers in matched primary tumor and lymph node metastases.
Author: Karamitopoulou, Eva|Zlobec, Inti|Koumarianou, Anna|Patsouris, Efstratios S|Peros, George|Lugli, Alessandro
PMID: 20572035
Journal: J Biochem. 2010 Sep;148(3):319-26.
Title: Effects of the biological clock gene Bmal1 on tumour growth and anti-cancer drug activity.
Author: Zeng, Zhao-Lei|Wu, Ming-Wei|Sun, Jian|Sun, Yue-Li|Cai, Yu-Chen|Huang, Yi-Jun|Xian, Li-Jian
PMID: 20576619
Journal: Oncogene. 2010 Oct 7;29(40):5464-74.
Title: PBK/TOPK interacts with the DBD domain of tumor suppressor p53 and modulates expression of transcriptional targets including p21.
Author: Hu, F|Gartenhaus, R B|Eichberg, D|Liu, Z|Fang, H-B|Rapoport, A P
PMID: 20622899
Journal: BMC Cancer. 2010 Jul 15;10:370.
Title: Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells.
Author: Sasaki, Kazuhito|Tsuno, Nelson H|Sunami, Eiji|Tsurita, Giichiro|Kawai, Kazushige|Okaji, Yurai|Nishikawa, Takeshi|Shuno, Yasutaka|Hongo, Kumiko|Hiyoshi, Masaya|Kaneko, Manabu|Kitayama, Joji|Takahashi, Koki|Nagawa, Hirokazu
PMID: 20630104
Journal: Eur J Cancer. 2010 Dec;46(18):3365-74.
Title: Molecular targets of apigenin in colorectal cancer cells: involvement of p21, NAG-1 and p53.
Author: Zhong, Yi|Krisanapun, Chutwadee|Lee, Seong-Ho|Nualsanit, Thararat|Sams, Carl|Peungvicha, Penchom|Baek, Seung Joon
PMID: 20709524
Journal: Cancer Prev Res (Phila). 2010 Sep;3(9):1187-97.
Title: Molecular alterations associated with sulindac-resistant colon tumors in ApcMin/+ mice.
Author: Greenspan, Emily J|Nichols, Frank C|Rosenberg, Daniel W
PMID: 20716632
Journal: Cell Cycle. 2010 Sep 1;9(17):3575-83.
Title: Evidence for a differential modulation of p53-phosphorylating kinases by the cyclin-dependent kinase inhibitor p21WAF1/CIP1.
Author: Neise, Denise|Sohn, Dennis|Budach, Wilfried|Janicke, Reiner U
PMID: 20818156
Journal: Clin Cancer Res. 2010 Sep 15;16(18):4595-606.
Title: Inhibitory effect of silibinin against azoxymethane-induced colon tumorigenesis in A/J mice.
Author: Ravichandran, Kameswaran|Velmurugan, Balaiya|Gu, Mallikarjuna|Singh, Rana P|Agarwal, Rajesh
PMID: 20823143
Journal: PLoS One. 2010 Sep 1;5(9).
Title: Prediction and testing of biological networks underlying intestinal cancer.
Author: Patel, Vishal N|Bebek, Gurkan|Mariadason, John M|Wang, Donghai|Augenlicht, Leonard H|Chance, Mark R
PMID: 20824133
Journal: J Biomed Sci. 2010 Sep 17;17:76.
Title: Suberoylanilide hydroxamic acid induces apoptosis and sub-G1 arrest of 320 HSR colon cancer cells.
Author: Sun, Pei-Chang|Tzao, Ching|Chen, Ban-Hen|Liu, Chen-Wei|Yu, Cheng-Ping|Jin, Jong-Shiaw
PMID: 20846458
Journal: PLoS One. 2010 Oct 1;5(10). pii: e13054.
Title: cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells.
Author: Shi, Ting|Mazumdar, Tapati|Devecchio, Jennifer|Duan, Zhong-Hui|Agyeman, Akwasi|Aziz, Mohammad|Houghton, Janet A
PMID: 20957031
Journal: BMC Cancer. 2010 Nov 6;10:610.
Title: Oridonin induces apoptosis and senescence in colorectal cancer cells by increasing histone hyperacetylation and regulation of p16, p21, p27 and c-myc.
Author: Gao, Feng-Hou|Hu, Xiao-Hui|Li, Wei|Liu, Hua|Zhang, Yan-Jie|Guo, Zhu-Ying|Xu, Mang-Hua|Wang, Shi-Ting|Jiang, Bin|Liu, Feng|Zhao, Ying-Zheng|Fang, Yong|Chen, Fang-Yuan|Wu, Ying-Li
PMID: 21054888
Journal: Zhong Xi Yi Jie He Xue Bao. 2010 Nov;8(11):1048-52.
Title: [Senescence-inducing effects of Chinese herbal medicine Tenglong Buzhong Decoction on human colon carcinoma LS-174-T cells and the mechanism].
Author: Hu, Bing|An, Hong-mei|Shen, Ke-ping|Du, Qin
PMID: 21078269
Journal: Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):20947-51.
Title: p53-mediated apoptosis requires inositol hexakisphosphate kinase-2.
Author: Koldobskiy, Michael A|Chakraborty, Anutosh|Werner, J Kent Jr|Snowman, Adele M|Juluri, Krishna R|Vandiver, M Scott|Kim, Seyun|Heletz, Shira|Snyder, Solomon H
PMID: 21078964
Journal: Exp Ther Med. 2010 Mar;1(2):369-375.
Title: Thymoquinone hydrazone derivatives cause cell cycle arrest in p53-competent colorectal cancer cells.
Author: Wirries, Andre|Breyer, Sandra|Quint, Karl|Schobert, Rainer|Ocker, Matthias
PMID: 22993551
Journal: Evid Based Complement Alternat Med. 2011;2011:984027.
Title: Inhibition of Anchorage-Independent Proliferation and G0/G1 Cell-Cycle Regulation in Human Colorectal Carcinoma Cells by 4,7-Dimethoxy-5-Methyl-l,3-Benzodioxole Isolated from the Fruiting Body of Antrodia camphorate.
Author: Lien, Hsiu-Man|Lin, Hsiao-Wei|Wang, Ying-Jan|Chen, Li-Ching|Yang, Ding-Yah|Lai, Ya-Yun|Ho, Yuan-Soon
PMID: 19293251
Journal: Invest New Drugs. 2011 Aug;29(4):627-36.
Title: Thioredoxin reductase inhibitor ethaselen increases the drug sensitivity of the colon cancer cell line LoVo towards cisplatin via regulation of G1 phase and reversal of G2/M phase arrest.
Author: Fu, Jia-Ning|Li, Jing|Tan, Qiang|Yin, Han-Wei|Xiong, Kun|Wang, Tian-Yu|Ren, Xiao-Yuan|Zeng, Hui-Hui
PMID: 20195699
Journal: Int J Cancer. 2011 Feb 1;128(3):551-61.
Title: DNMT3a plays a role in switches between doxorubicin-induced senescence and apoptosis of colorectal cancer cells.
Author: Zhang, Yu|Gao, Yanyan|Zhang, Guoping|Huang, Shuyan|Dong, Zhixiong|Kong, Chenfei|Su, Dongmei|Du, Juan|Zhu, Shan|Liang, Qian|Zhang, Jianchao|Lu, Jun|Huang, Baiqu
PMID: 20473858
Journal: Int J Cancer. 2011 Mar 1;128(5):1080-94.
Title: Prognostic significance of CDKN2A (p16) promoter methylation and loss of expression in 902 colorectal cancers: Cohort study and literature review.
Author: Shima, Kaori|Nosho, Katsuhiko|Baba, Yoshifumi|Cantor, Mami|Meyerhardt, Jeffrey A|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji
PMID: 20473920
Journal: Med Oncol. 2011 Dec;28(4):1495-506.
Title: Down-regulation of phospho-non-receptor Src tyrosine kinases contributes to growth inhibition of cervical cancer cells.
Author: Kong, Lu|Deng, Zhihong|Zhao, Yanzhong|Wang, Yamei|Sarkar, Fazlul H|Zhang, Yuxiang
PMID: 20532678
Journal: Integr Cancer Ther. 2011 Mar;10(1):58-69.
Title: Regulation of p21, MMP-1, and MDR-1 expression in human colon carcinoma HT29 cells by Tian Xian liquid, a chinese medicinal formula, in vitro and in vivo.
Author: Sze, Stephen C W|Wong, Kam L|Liu, Wing K|Ng, Tzi B|Wong, Jack H|Cheung, Ho P|Yow, Christine M L|Chu, Ellie S M|Qing Liu|Hu, Yong M|Tsang, Kam W|Lee, Wai S|Yao Tong
PMID: 20702488
Journal: J Cell Mol Med. 2011 Jul;15(7):1528-41.
Title: Cutting edge: Chk1 directs senescence and mitotic catastrophe in recovery from G(2) checkpoint arrest.
Author: Poehlmann, Angela|Habold, Caroline|Walluscheck, Diana|Reissig, Kathrin|Bajbouj, Khuloud|Ullrich, Oliver|Hartig, Roland|Gali-Muhtasib, Hala|Diestel, Antje|Roessner, Albert|Schneider-Stock, Regine
PMID: 20716119
Journal: Cancer Chemother Pharmacol. 2011 Jun;67(6):1299-312.
Title: Satraplatin (JM-216) mediates G2/M cell cycle arrest and potentiates apoptosis via multiple death pathways in colorectal cancer cells thus overcoming platinum chemo-resistance.
Author: Kalimutho, Murugan|Minutolo, Antonella|Grelli, Sandro|Formosa, Amanda|Sancesario, Giulia|Valentini, Alessandra|Federici, Giorgio|Bernardini, Sergio
PMID: 20734047
Journal: Oncogene. 2011 Feb 10;30(6):737-50.
Title: Reversion-inducing cysteine-rich protein with Kazal motifs interferes with epidermal growth factor receptor signaling.
Author: Kitajima, S|Miki, T|Takegami, Y|Kido, Y|Noda, M|Hara, E|Shamma, A|Takahashi, C
PMID: 20890302
Journal: Ann Surg Oncol. 2011 Apr;18(4):1166-74.
Title: Significance of Lgr5(+ve) cancer stem cells in the colon and rectum.
Author: Takahashi, Hidekazu|Ishii, Hideshi|Nishida, Naohiro|Takemasa, Ichiro|Mizushima, Tsunekazu|Ikeda, Masataka|Yokobori, Takehiko|Mimori, Koshi|Yamamoto, Hirofumi|Sekimoto, Mitsugu|Doki, Yuichiro|Mori, Masaki
PMID: 21125339
Journal: Nutr Cancer. 2011;63(1):139-50.
Title: Estrogen receptor-beta mediates the inhibition of DLD-1 human colon adenocarcinoma cells by soy isoflavones.
Author: Bielecki, Agnieszka|Roberts, Jennifer|Mehta, Rekha|Raju, Jayadev
PMID: 21161820
Journal: Int J Oncol. 2011 Feb;38(2):529-36.
Title: Involvement of p21cip1/waf1 in the anti-proliferative effects of polyethylene glycol in colon carcinogenesis.
Author: Roy, Hemant K|Koetsier, Jennifer L|Tiwari, Ashish K|Joshi, Suhasini|Kunte, Dhananjay P|Ward, Tina P|Gandhi, Seema R|Wali, Ramesh K
PMID: 21170505
Journal: BMC Cancer. 2011 Jan 11;11:11.
Title: ABI3 ectopic expression reduces in vitro and in vivo cell growth properties while inducing senescence.
Author: Latini, Flavia R M|Hemerly, Jefferson P|Freitas, Beatriz C G|Oler, Gisele|Riggins, Gregory J|Cerutti, Janete M
PMID: 21223585
Journal: Int J Oncol. 2011 Mar;38(3):761-7.
Title: Ganodermanontriol, a lanostanoid triterpene from Ganoderma lucidum, suppresses growth of colon cancer cells through ss-catenin signaling.
Author: Jedinak, Andrej|Thyagarajan-Sahu, Anita|Jiang, Jiahua|Sliva, Daniel
PMID: 21225227
Journal: Mol Carcinog. 2011 Jul;50(7):553-62.
Title: Grape seed extract upregulates p21 (Cip1) through redox-mediated activation of ERK1/2 and posttranscriptional regulation leading to cell cycle arrest in colon carcinoma HT29 cells.
Author: Kaur, Manjinder|Tyagi, Alpna|Singh, Rana P|Sclafani, Robert A|Agarwal, Rajesh|Agarwal, Chapla
PMID: 21268136
Journal: Nature. 2011 Feb 17;470(7334):409-13.
Title: CKIalpha ablation highlights a critical role for p53 in invasiveness control.
Author: Elyada, Ela|Pribluda, Ariel|Goldstein, Robert E|Morgenstern, Yael|Brachya, Guy|Cojocaru, Gady|Snir-Alkalay, Irit|Burstain, Ido|Haffner-Krausz, Rebecca|Jung, Steffen|Wiener, Zoltan|Alitalo, Kari|Oren, Moshe|Pikarsky, Eli|Ben-Neriah, Yinon
PMID: 21331045
Journal: Virchows Arch. 2011 Apr;458(4):431-8.
Title: Expression of p21WAF1 in Astler-Coller stage B2 colorectal cancer is associated with survival benefit from 5FU-based adjuvant chemotherapy.
Author: Sulzyc-Bielicka, Violetta|Domagala, Pawel|Urasinska, Elzbieta|Bielicki, Dariusz|Safranow, Krzysztof|Domagala, Wenancjusz
PMID: 21369800
Journal: Liver Int. 2011 Apr;31(4):561-71.
Title: Aflatoxin genotoxicity is associated with a defective DNA damage response bypassing p53 activation.
Author: Gursoy-Yuzugullu, Ozge|Yuzugullu, Haluk|Yilmaz, Mustafa|Ozturk, Mehmet
PMID: 21382167
Journal: Chin J Cancer. 2011 Apr;30(4):254-63.
Title: Association between p21 Ser31Arg polymorphism and cancer risk: a meta-analysis.
Author: Ma, Hongxia|Zhou, Ziyuan|Wei, Sheng|Wei, Qingyi
PMID: 21439247
Journal: Mol Nutr Food Res. 2011 Apr;55(4):623-34.
Title: Lunasin induces apoptosis and modifies the expression of genes associated with extracellular matrix and cell adhesion in human metastatic colon cancer cells.
Author: Dia, Vermont P|Gonzalez de Mejia, Elvira
PMID: 21462330
Journal: Cell Death Differ. 2011 Oct;18(10):1664-74.
Title: Caspase-2 is required for DNA damage-induced expression of the CDK inhibitor p21(WAF1/CIP1).
Author: Sohn, D|Budach, W|Janicke, R U
PMID: 21475302
Journal: Biochem Cell Biol. 2011 Jun;89(3):287-98.
Title: LYG-202 inhibits the proliferation of human colorectal carcinoma HCT-116 cells through induction of G1/S cell cycle arrest and apoptosis via p53 and p21(WAF1/Cip1) expression.
Author: Liu, Wei|Dai, Qinsheng|Lu, Na|Wei, Libin|Ha, Jun|Rong, Jingjing|Mu, Rong|You, Qidong|Li, Zhiyu|Guo, Qinglong
PMID: 21491996
Journal: Nutr Cancer. 2011;63(4):611-22.
Title: The antiproliferative effect of dietary fiber phenolic compounds ferulic acid and p-coumaric acid on the cell cycle of Caco-2 cells.
Author: Janicke, Birgit|Hegardt, Cecilia|Krogh, Morten|Onning, Gunilla|Akesson, Bjorn|Cirenajwis, Helena M|Oredsson, Stina M
PMID: 21500097
Journal: Biochem Biophys Res Commun. 2011 May 27;409(1):75-81.
Title: Induction of apoptosis in colon cancer cells by a novel topoisomerase I inhibitor TopIn.
Author: Bae, Soo Kyung|Gwak, Jungsug|Song, Im-Sook|Park, Hyung-Soon|Oh, Sangtaek
PMID: 21549095
Journal: Hum Pathol. 2011 Dec;42(12):1888-96.
Title: Systematic analysis of proteins from different signaling pathways in the tumor center and the invasive front of colorectal cancer.
Author: Karamitopoulou, Eva|Zlobec, Inti|Panayiotides, Ioannis|Patsouris, Efstratios S|Peros, George|Rallis, George|Lapas, Christos|Karakitsos, Petros|Terracciano, Luigi M|Lugli, Alessandro
PMID: 21664646
Journal: Hum Pathol. 2011 Dec;42(12):1897-910.
Title: Distinctive patterns of p53 protein expression and microsatellite instability in human colorectal cancer.
Author: Nyiraneza, Christine|Jouret-Mourin, Anne|Kartheuser, Alex|Camby, Philippe|Plomteux, Olivier|Detry, Roger|Dahan, Karin|Sempoux, Christine
PMID: 21665242
Journal: Cancer Lett. 2011 Oct 1;309(1):78-84.
Title: SUMO-specific protease 1 regulates the in vitro and in vivo growth of colon cancer cells with the upregulated expression of CDK inhibitors.
Author: Xu, Ying|Li, Jie|Zuo, Yong|Deng, Jiong|Wang, Li-Shun|Chen, Guo-Qiang
PMID: 21669491
Journal: Gastroenterology. 2011 Oct;141(4):1381-92.
Title: Notch1 regulates the effects of matrix metalloproteinase-9 on colitis-associated cancer in mice.
Author: Garg, Pallavi|Jeppsson, Sabrina|Dalmasso, Guillaume|Ghaleb, Amr M|McConnell, Beth B|Yang, Vincent W|Gewirtz, Andrew T|Merlin, Didier|Sitaraman, Shanthi V
PMID: 21723221
Journal: J Agric Food Chem. 2011 Aug 24;59(16):9011-21.
Title: Consumption of lycopene inhibits the growth and progression of colon cancer in a mouse xenograft model.
Author: Tang, Feng-Yao|Pai, Man-Hui|Wang, Xiang-Dong
PMID: 21744871
Journal: Cancer Res. 2011 Sep 1;71(17):5904-14.
Title: Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells.
Author: Mazumdar, Tapati|Devecchio, Jennifer|Agyeman, Akwasi|Shi, Ting|Houghton, Janet A
PMID: 21747117
Journal: Oncol Res. 2011;19(6):265-74.
Title: Evaluation of an 18F-labeled oligonucleotide probe targeting p21(WAF1) transcriptional changes in human tumor cells.
Author: Koslowsky, I|Shahhosseini, S|Mirzayans, R|Murray, D|Mercer, J
PMID: 21776822
Journal: PLoS One. 2011;6(8):e23577.
Title: Serum-nutrient starvation induces cell death mediated by Bax and Puma that is counteracted by p21 and unmasked by Bcl-x(L) inhibition.
Author: Braun, Frederique|Bertin-Ciftci, Josephine|Gallouet, Anne-Sophie|Millour, Julie|Juin, Philippe
PMID: 21887277
Journal: Acta Pharmacol Sin. 2011 Nov;32(11):1387-96.
Title: Platinum-(IV)-derivative satraplatin induced G2/M cell cycle perturbation via p53-p21(waf1/cip1)-independent pathway in human colorectal cancer cells.
Author: Kalimutho, Murugan|Minutolo, Antonella|Grelli, Sandro|Federici, Giorgio|Bernardini, Sergio
PMID: 21927014
Journal: Mol Cancer. 2011 Nov 23;10:144.
Title: Anti-tumor effects of fibroblast growth factor-binding protein (FGF-BP) knockdown in colon carcinoma.
Author: Schulze, Daniel|Plohmann, Philipp|Hobel, Sabrina|Aigner, Achim
PMID: 22111880
Journal: World J Gastroenterol. 2011 Nov 14;17(42):4711-7.
Title: miR-93 suppresses proliferation and colony formation of human colon cancer stem cells.
Author: Yu, Xiao-Feng|Zou, Jian|Bao, Zhi-Jun|Dong, Jie
PMID: 22180714
Journal: Exp Ther Med. 2011 Mar;2(2):301-307.
Title: Valproate inhibits colon cancer growth through cell cycle modification in vivo and in vitro.
Author: Strey, Christoph W|Schamell, Lea|Oppermann, Elsie|Haferkamp, Axel|Bechstein, Wolf O|Blaheta, Roman A
PMID: 22977502
Journal: J Nutr Biochem. 2012 Jul;23(7):706-15.
Title: 4-O-methylhonokiol inhibits colon tumor growth via p21-mediated suppression of NF-kappaB activity.
Author: Oh, Ju Hoon|Ban, Jung Ok|Cho, Min-Chul|Jo, Miran|Jung, Jae Kyung|Ahn, Byeongwoo|Yoon, Do-Young|Han, Sang Bae|Hong, Jin Tae
PMID: 21820300
Journal: Int J Oncol. 2012 Jan;40(1):170-5.
Title: Anti-carcinogenic properties of omeprazole against human colon cancer cells and azoxymethane-induced colonic aberrant crypt foci formation in rats.
Author: Patlolla, Jagan M R|Zhang, Yuting|Li, Qian|Steele, Vernon E|Rao, Chinthalapally V
PMID: 21956158
Journal: Cell Signal. 2012 Jan;24(1):316-24.
Title: The p53-p21WAF1 checkpoint pathway plays a protective role in preventing DNA rereplication induced by abrogation of FOXF1 function.
Author: Lo, Pang-Kuo|Lee, Ji Shin|Sukumar, Saraswati
PMID: 21964066
Journal: Anticancer Drugs. 2012 Feb;23(2):191-9.
Title: B1, a novel topoisomerase II inhibitor, induces apoptosis and cell cycle G1 arrest in lung adenocarcinoma A549 cells.
Author: Cheng, Meng-Hsuan|Yang, Yu-Chiao|Wong, Yun-Hong|Chen, Tsuei-Ru|Lee, Chia-Yu|Yang, Chun-Chien|Chen, Shih-Hua|Yang, I-Ning|Yang, Ya-Shiu|Huang, Hsu-Shan|Yang, Chun-Yuh|Huang, Ming-Shyan|Chiu, Hui-Fen
PMID: 22008852
Journal: Int J Cancer. 2012 Sep 15;131(6):1435-44.
Title: Chemoprevention of familial adenomatous polyposis by bromo-noscapine (EM011) in the Apc(Min/+) mouse model.
Author: Li, Shiwang|Ghaleb, Amr M|He, Jing|Bughani, Usha|Bialkowska, Agnieszka B|Yang, Vincent W|Joshi, Harish C
PMID: 22052467
Journal: Oncol Rep. 2012 Feb;27(2):529-34.
Title: Role of p21 as a determinant of 1,6-Bis[4-(4-amino-3-hydroxyphenoxy)phenyl] diamantane response in human HCT-116 colon carcinoma cells.
Author: Wang, Jane-Jen|Hung, Hui-Fang|Huang, Min-Li|Lee, Hui-Ju|Chern, Yaw-Terng|Chang, Yuh-Fang|Chi, Chin-Wen|Hsu, Yi-Chiung
PMID: 22076474
Journal: Cell Signal. 2012 Mar;24(3):718-25.
Title: Stat6 activity-related Th2 cytokine profile and tumor growth advantage of human colorectal cancer cells in vitro and in vivo.
Author: Li, Ben Hui|Xu, Shuang Bing|Li, Feng|Zou, Xiao Guang|Saimaiti, Abudukeyoumu|Simayi, Dilixia|Wang, Ying Hong|Zhang, Yan|Yuan, Jia|Zhang, Wen Jie
PMID: 22108090
Journal: Carcinogenesis. 2012 Feb;33(2):326-30.
Title: Decorin-mediated inhibition of colorectal cancer growth and migration is associated with E-cadherin in vitro and in mice.
Author: Bi, Xiuli|Pohl, Nicole M|Qian, Zhibin|Yang, George R|Gou, Yuan|Guzman, Grace|Kajdacsy-Balla, Andre|Iozzo, Renato V|Yang, Wancai
PMID: 22159220
Journal: Ann Surg Oncol. 2012 Aug;19(8):2753-62.
Title: UHRF1 promotes cell growth and metastasis through repression of p16(ink(4)a) in colorectal cancer.
Author: Wang, Feng|Yang, Yong-Zhi|Shi, Chen-Zhang|Zhang, Peng|Moyer, Mary Pat|Zhang, Hui-Zhen|Zou, Yang|Qin, Huan-Long
PMID: 22219067
Journal: J Nutr Biochem. 2012 Oct;23(10):1302-13.
Title: Consumption of high-fat diet induces tumor progression and epithelial-mesenchymal transition of colorectal cancer in a mouse xenograft model.
Author: Tang, Feng-Yao|Pai, Man-Hui|Chiang, En-Pei Isabel
PMID: 22221675
Journal: Carcinogenesis. 2012 Apr;33(4):732-9.
Title: MiR-30a-5p suppresses tumor growth in colon carcinoma by targeting DTL.
Author: Baraniskin, Alexander|Birkenkamp-Demtroder, Karin|Maghnouj, Abdelouahid|Zollner, Hannah|Munding, Johanna|Klein-Scory, Susanne|Reinacher-Schick, Anke|Schwarte-Waldhoff, Irmgard|Schmiegel, Wolff|Hahn, Stephan A
PMID: 22287560
Journal: Ann Surg Oncol. 2012 Jul;19 Suppl 3:S682-92.
Title: Cell cycle proteins predict recurrence in stage II and III colon cancer.
Author: Belt, Eric J Th|Brosens, Rebecca P M|Delis-van Diemen, Pien M|Bril, Herman|Tijssen, Marianne|van Essen, Dirk F|Heymans, Martijn W|Belien, Jeroen A M|Stockmann, Hein B A C|Meijer, Sybren|Meijer, Gerrit A
PMID: 22311118
Journal: Expert Opin Ther Targets. 2012 Mar;16 Suppl 1:S103-9.
Title: Antiproliferative effects of a new alpha-lipoic acid derivative, DHL-HisZnNa, in HT29 human colon cancer cells in vitro.
Author: Kono, Yohei|Inomata, Masafumi|Hagiwara, Satoshi|Hiratsuka, Takahiro|Suzuki, Kosuke|Koga, Hironori|Shiraishi, Norio|Noguchi, Takayuki|Kitano, Seigo
PMID: 22313417
Journal: Amino Acids. 2012 Oct;43(4):1663-70.
Title: Kynurenic acid in human renal cell carcinoma: its antiproliferative and antimigrative action on Caki-2 cells.
Author: Walczak, Katarzyna|Zurawska, Malgorzata|Kis, Jacek|Starownik, Radoslaw|Zgrajka, Wojciech|Bar, Krzysztof|Turski, Waldemar A|Rzeski, Wojciech
PMID: 22349835
Journal: J Agric Food Chem. 2012 Apr 11;60(14):3612-8.
Title: In vivo antitumor effects of 4,7-dimethoxy-5-methyl-1,3-benzodioxole isolated from the fruiting body of Antrodia camphorata through activation of the p53-mediated p27/Kip1 signaling pathway.
Author: Tu, Shih-Hsin|Wu, Chih-Hsiung|Chen, Li-Ching|Huang, Ching-Shui|Chang, Hui-Wen|Chang, Chien-Hsi|Lien, Hsiu-Man|Ho, Yuan-Soon
PMID: 22429157
Journal: Cancer Res. 2012 Jun 15;72(12):3020-8.
Title: Postmenopausal hormone therapy is associated with a reduced risk of colorectal cancer lacking CDKN1A expression.
Author: Lin, Jennifer H|Morikawa, Teppei|Chan, Andrew T|Kuchiba, Aya|Shima, Kaori|Nosho, Katsuhiko|Kirkner, Gregory|Zhang, Shumin M|Manson, Joann E|Giovannucci, Edward|Fuchs, Charles S|Ogino, Shuji
PMID: 22511578
Journal: Int J Radiat Oncol Biol Phys. 2012 Dec 1;84(5):1151-8.
Title: Upregulation of trefoil factor 3 (TFF3) after rectal cancer chemoradiotherapy is an adverse prognostic factor and a potential therapeutic target.
Author: Casado, Enrique|Garcia, Victor Moreno|Sanchez, Jose Javier|Gomez Del Pulgar, Maria Teresa|Feliu, Jaime|Maurel, Joan|Castelo, Beatriz|Moreno Rubio, Juan|Lopez, Rocio A B|Garcia-Cabezas, Miguel Angel|Burgos, Emilio|de Castro, Javier|Belda-Iniesta, Cristobal
PMID: 22516806
Journal: Cancer Res. 2012 Jul 1;72(13):3251-9.
Title: Chk2 phosphorylation of survivin-DeltaEx3 contributes to a DNA damage-sensing checkpoint in cancer.
Author: Lopergolo, Alessia|Tavecchio, Michele|Lisanti, Sofia|Ghosh, Jagadish C|Dohi, Takehiko|Faversani, Alice|Vaira, Valentina|Bosari, Silvano|Tanigawa, Nobuhiko|Delia, Domenico|Kossenkov, Andrew V|Showe, Louise C|Altieri, Dario C
PMID: 22586065
Journal: Nat Genet. 2012 May 27;44(7):770-6.
Title: Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk.
Author: Dunlop, Malcolm G|Dobbins, Sara E|Farrington, Susan Mary|Jones, Angela M|Palles, Claire|Whiffin, Nicola|Tenesa, Albert|Spain, Sarah|Broderick, Peter|Ooi, Li-Yin|Domingo, Enric|Smillie, Claire|Henrion, Marc|Frampton, Matthew|Martin, Lynn|Grimes, Graeme|Gor
PMID: 22634755
Journal: PLoS One. 2012;7(5):e37572.
Title: Hydrogen sulfide lowers proliferation and induces protective autophagy in colon epithelial cells.
Author: Wu, Ya C|Wang, Xiao J|Yu, Le|Chan, Francis K L|Cheng, Alfred S L|Yu, Jun|Sung, Joseph J Y|Wu, William K K|Cho, Chi H
PMID: 22679478
Journal: Oncol Rep. 2012 Sep;28(3):855-61.
Title: Gene expression profiles of tumor regression grade in locally advanced rectal cancer after neoadjuvant chemoradiotherapy.
Author: Saigusa, Susumu|Tanaka, Koji|Toiyama, Yuji|Matsushita, Kohei|Kawamura, Mikio|Okugawa, Yoshinaga|Hiro, Junichiro|Inoue, Yasuhiro|Uchida, Keiichi|Mohri, Yasuhiko|Kusunoki, Masato
PMID: 22711167
Journal: Evid Based Complement Alternat Med. 2012;2012:326096.
Title: 6-Gingerol Inhibits Growth of Colon Cancer Cell LoVo via Induction of G2/M Arrest.
Author: Lin, Ching-Bin|Lin, Chun-Che|Tsay, Gregory J
PMID: 22719783
Journal: Oncol Lett. 2012 Feb;3(2):441-444.
Title: MLH1-deficient HCT116 colon tumor cells exhibit resistance to the cytostatic and cytotoxic effect of the poly(A) polymerase inhibitor cordycepin (3'-deoxyadenosine) in vitro.
Author: Imesch, Patrick|Goerens, Anouk|Fink, Daniel|Fedier, Andre
PMID: 22740928
Journal: Int J Mol Sci. 2012;13(5):6117-28.
Title: Hedyotis diffusa Willd inhibits colorectal cancer growth in vivo via inhibition of STAT3 signaling pathway.
Author: Cai, Qiaoyan|Lin, Jiumao|Wei, Lihui|Zhang, Ling|Wang, Lili|Zhan, Youzhi|Zeng, Jianwei|Xu, Wei|Shen, Aling|Hong, Zhenfeng|Peng, Jun
PMID: 22754353
Journal: PLoS One. 2012;7(6):e39381.
Title: Effects of activin and TGFbeta on p21 in colon cancer.
Author: Bauer, Jessica|Sporn, Judith C|Cabral, Jennifer|Gomez, Jessica|Jung, Barbara
PMID: 22761777
Journal: Pharmacol Rep. 2012;64(3):745-50.
Title: Kynurenic acid enhances expression of p21 Waf1/Cip1 in colon cancer HT-29 cells.
Author: Walczak, Katarzyna|Turski, Waldemar A|Rzeski, Wojciech
PMID: 22814028
Journal: Clin Cancer Res. 2012 Sep 15;18(18):4942-53.
Title: Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine.
Author: Prasad, Sahdeo|Yadav, Vivek R|Sung, Bokyung|Reuter, Simone|Kannappan, Ramaswamy|Deorukhkar, Amit|Diagaradjane, Parmeswaran|Wei, Caimiao|Baladandayuthapani, Veerabhadran|Krishnan, Sunil|Guha, Sushovan|Aggarwal, Bharat B
PMID: 22832932
Journal: Oncol Rep. 2012 Nov;28(5):1551-8.
Title: Exosomes secreted from human colorectal cancer cell lines contain mRNAs, microRNAs and natural antisense RNAs, that can transfer into the human hepatoma HepG2 and lung cancer A549 cell lines.
Author: Chiba, Mitsuru|Kimura, Misako|Asari, Saya
PMID: 22895844
Journal: Br J Nutr. 2012 Aug;108 Suppl 1:S145-54.
Title: Non-digestible fraction of beans (Phaseolus vulgaris L.) modulates signalling pathway genes at an early stage of colon cancer in Sprague-Dawley rats.
Author: Hayde, Vergara-Castaneda|Ramon, Guevara-Gonzalez|Lorenzo, Guevara-Olvera|Dave, Oomah B|Rosalia, Reynoso-Camacho|Paul, Wiersma|Guadalupe, Loarca-Pina
PMID: 22916810
Journal: Mol Nutr Food Res. 2012 Oct;56(10):1520-31.
Title: Concomitant consumption of lycopene and fish oil inhibits tumor growth and progression in a mouse xenograft model of colon cancer.
Author: Tang, Feng-Yao|Pai, Man-Hui|Kuo, Yueh-Hsiung|Wang, Xiang-Dong
PMID: 22961879
Journal: Biochem Pharmacol. 2012 Nov 1;84(9):1133-42.
Title: Novel mithramycins abrogate the involvement of protein factors in the transcription of cell cycle control genes.
Author: Vizcaino, Carolina|Mansilla, Sylvia|Nunez, Luz-Elena|Mendez, Carmen|Salas, Jose A|Moris, Francisco|Portugal, Jose
PMID: 22981341
Journal: Mol Cancer Ther. 2012 Nov;11(11):2311-20.
Title: Targeting protein tyrosine kinase 6 enhances apoptosis of colon cancer cells following DNA damage.
Author: Gierut, Jessica J|Mathur, Priya S|Bie, Wenjun|Han, Jin|Tyner, Angela L
PMID: 22989419
Journal: Asian Pac J Cancer Prev. 2012;13(7):3233-8.
Title: MSP58 knockdown inhibits the proliferation of esophageal squamous cell carcinoma in vitro and in vivo.
Author: Xu, Chun-Sheng|Zheng, Jian-Yong|Zhang, Hai-Long|Zhao, Hua-Dong|Zhang, Jing|Wu, Guo-Qiang|Wu, Lin|Wang, Qing|Wang, Wei-Zhong|Zhang, Jian
PMID: 22994740
Journal: Asian Pac J Cancer Prev. 2012;13(8):3757-61.
Title: Crocetin induces cytotoxicity in colon cancer cells via p53-independent mechanisms.
Author: Li, Cai-Yan|Huang, Wen-Feng|Wang, Qun-Li|Wang, Fan|Cai, E|Hu, Bing|Du, Jia-Cheng|Wang, Jing|Chen, Rong|Cai, Xiao-Jing|Feng, Jing|Li, Hui-Hui
PMID: 23098467
Journal: Biochem Biophys Res Commun. 2012 Dec 14;429(3-4):173-9.
Title: MiR-186, miR-216b, miR-337-3p, and miR-760 cooperatively induce cellular senescence by targeting alpha subunit of protein kinase CKII in human colorectal cancer cells.
Author: Kim, Soo Young|Lee, Young-Hoon|Bae, Young-Seuk
PMID: 23137536
Journal: Exp Ther Med. 2012 Aug;4(2):307-310.
Title: Hedyotis diffusa Willd extract inhibits HT-29 cell proliferation via cell cycle arrest.
Author: Lin, Minghe|Lin, Jiumao|Wei, Lihui|Xu, Wei|Hong, Zhenfeng|Cai, Qiaoyan|Peng, Jun|Zhu, Dezeng
PMID: 23139718
Journal: J Carcinog. 2012;11:13.
Title: Inhibitory effects of meju prepared with mixed starter cultures on azoxymethane and dextran sulfate sodium-induced colon carcinogenesis in mice.
Author: Jeong, Ji-Kang|Chang, Hee-Kyung|Park, Kun-Young
PMID: 23230391
Journal: J Cancer Res Ther. 2012 Oct-Dec;8(4):532-6.
Title: The in vivo antitumor effects on human COLO 205 cancer cells of the 4,7-dimethoxy-5-(2-propen-1-yl)-1,3-benzodioxole (apiole) derivative of 5-substituted 4,7-dimethoxy-5-methyl-l,3-benzodioxole (SY-1) isolated from the fruiting body of Antrodia camphorate
Author: Wei, Po-Li|Tu, Shih-Hsin|Lien, Hsiu-Man|Chen, Li-Ching|Chen, Ching-Shyang|Wu, Chih-Hsiung|Huang, Ching-Shui|Chang, Hui-Wen|Chang, Chien-Hsi|Tseng, How|Ho, Yuan-Soon
PMID: 23361270
Journal: Mol Carcinog. 2013 Jan;52(1):1-17.
Title: Cladosporol a stimulates G1-phase arrest of the cell cycle by up-regulation of p21(waf1/cip1) expression in human colon carcinoma HT-29 cells.
Author: Zurlo, Diana|Leone, Cinzia|Assante, Gemma|Salzano, Salvatore|Renzone, Giovanni|Scaloni, Andrea|Foresta, Caterina|Colantuoni, Vittorio|Lupo, Angelo
PMID: 22025467
Journal: Mol Carcinog. 2013 Jun;52(6):459-74.
Title: Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster.
Author: Humphreys, Karen J|Cobiac, Lynne|Le Leu, Richard K|Van der Hoek, Mark B|Michael, Michael Z
PMID: 22308110
Journal: Oncogene. 2013 Jan 31;32(5):577-88.
Title: Synthetic lethality of Chk1 inhibition combined with p53 and/or p21 loss during a DNA damage response in normal and tumor cells.
Author: Origanti, S|Cai, S-r|Munir, A Z|White, L S|Piwnica-Worms, H
PMID: 22430210
Journal: Int J Food Sci Nutr. 2013 Feb;64(1):36-43.
Title: The inhibitory effects and mechanisms of rhamnogalacturonan I pectin from potato on HT-29 colon cancer cell proliferation and cell cycle progression.
Author: Cheng, Hairong|Zhang, Zhongyu|Leng, Jiayi|Liu, Dan|Hao, Miao|Gao, Xiaoge|Tai, Guihua|Zhou, Yifa
PMID: 22694196
Journal: Int J Cancer. 2013 Feb 1;132(3):707-16.
Title: Antitumor effects of novel compound, guttiferone K, on colon cancer by p21Waf1/Cip1-mediated G(0) /G(1) cell cycle arrest and apoptosis.
Author: Kan, Winnie Lai Ting|Yin, Chun|Xu, Hong Xi|Xu, Gang|To, Kenneth Kin Wah|Cho, Chi Hin|Rudd, John Anthony|Lin, Ge
PMID: 22733377
Journal: Gut. 2013 Apr;62(4):561-70.
Title: Salutary effects of adiponectin on colon cancer: in vivo and in vitro studies in mice.
Author: Moon, Hyun-Seuk|Liu, Xiaowen|Nagel, Jutta M|Chamberland, John P|Diakopoulos, Kalliope N|Brinkoetter, Mary T|Hatziapostolou, Maria|Wu, Yan|Robson, Simon C|Iliopoulos, Dimitrios|Mantzoros, Christos S
PMID: 22735569
Journal: Int J Cancer. 2013 Apr 1;132(7):1537-46.
Title: Expression of the MAP kinase phosphatase DUSP4 is associated with microsatellite instability in colorectal cancer (CRC) and causes increased cell proliferation.
Author: Groschl, Benedikt|Bettstetter, Marcus|Giedl, Christian|Woenckhaus, Matthias|Edmonston, Tina|Hofstadter, Ferdinand|Dietmaier, Wolfgang
PMID: 22965873
Journal: Exp Mol Pathol. 2013 Feb;94(1):262-9.
Title: Cytoplasmic mislocalization of overexpressed FOXF1 is associated with the malignancy and metastasis of colorectal adenocarcinomas.
Author: Lo, Pang-Kuo|Lee, Ji Shin|Chen, Hexin|Reisman, David|Berger, Franklin G|Sukumar, Saraswati
PMID: 23103611
Journal: Int J Oncol. 2013 Jan;42(1):161-7.
Title: SSEA-3 as a novel amplifying cancer cell surface marker in colorectal cancers.
Author: Suzuki, Yozo|Haraguchi, Naotsugu|Takahashi, Hidekazu|Uemura, Mamoru|Nishimura, Junichi|Hata, Taishi|Takemasa, Ichiro|Mizushima, Tsunekazu|Ishii, Hideshi|Doki, Yuichiro|Mori, Masaki|Yamamoto, Hirofumi
PMID: 23175153
Journal: Biochem Biophys Res Commun. 2013 Jan 11;430(2):653-8.
Title: p21(WAF(1)/C(1)P(1)) deficiency induces mitochondrial dysfunction in HCT116 colon cancer cells.
Author: Kim, Ae Jeong|Jee, Hye Jin|Song, Naree|Kim, Minjee|Jeong, Seon-Young|Yun, Jeanho
PMID: 23211592
Journal: Oncol Lett. 2013 Jan;5(1):305-310.
Title: Anticancer potential of an ethanol extract of Asiasari radix against HCT-116 human colon cancer cells in vitro.
Author: Oh, Se-Mi|Kim, Jinhee|Lee, Jun|Yi, Jin-Mu|Oh, Dal-Seok|Bang, Ok-Sun|Kim, No Soo
PMID: 23255939
Journal: Food Chem Toxicol. 2013 May;55:424-33.
Title: Suppression of Src/ERK and GSK-3/beta-catenin signaling by pinosylvin inhibits the growth of human colorectal cancer cells.
Author: Park, Eun-Jung|Chung, Hwa-Jin|Park, Hyen Joo|Kim, Gi Dae|Ahn, Yong-Hyun|Lee, Sang Kook
PMID: 23333577
Journal: Radiat Res. 2013 Mar;179(3):282-92.
Title: Gamma irradiation and targeted radionuclides enhance the expression of the noradrenaline transporter transgene controlled by the radio-inducible p21(WAF1/CIP1) promoter.
Author: McCluskey, Anthony G|Mairs, Robert J|Sorensen, Annette|Robson, Tracy|McCarthy, Helen O|Pimlott, Sally L|Babich, John W|Champion, Sue|Boyd, Marie
PMID: 23336184
Journal: Phytomedicine. 2013 Apr 15;20(6):512-20.
Title: beta-Asarone induces senescence in colorectal cancer cells by inducing lamin B1 expression.
Author: Liu, Linna|Wang, Jingjie|Shi, Lei|Zhang, Wenjuan|Du, Xiaoyan|Wang, Zhipeng|Zhang, Yan
PMID: 23357361
Journal: Cell Physiol Biochem. 2013;31(1):113-22.
Title: External Qi of Yan Xin Qigong inhibits activation of Akt, Erk1/2 and NF-kB and induces cell cycle arrest and apoptosis in colorectal cancer cells.
Author: Yan, Xin|Shen, Hua|Jiang, Hongjian|Hu, Dan|Wang, Jun|Wu, Xinqi
PMID: 23363659
Journal: J Agric Food Chem. 2013 Mar 20;61(11):2811-9.
Title: P27/Kip1 is responsible for magnolol-induced U373 apoptosis in vitro and in vivo.
Author: Chen, Li-Ching|Lee, Wen-Sen
PMID: 23448150
Journal: Mol Pharmacol. 2013 Jul;84(1):25-40.
Title: Pharmacological inhibition of platelet-tumor cell cross-talk prevents platelet-induced overexpression of cyclooxygenase-2 in HT29 human colon carcinoma cells.
Author: Dovizio, Melania|Maier, Thorsten J|Alberti, Sara|Di Francesco, Luigia|Marcantoni, Emanuela|Munch, Gotz|John, Constance M|Suess, Beatrix|Sgambato, Alessandro|Steinhilber, Dieter|Patrignani, Paola
PMID: 23580446
Journal: Biochim Biophys Acta. 2013 Aug;1830(8):4053-64.
Title: Simvastatin induced HCT116 colorectal cancer cell apoptosis through p38MAPK-p53-survivin signaling cascade.
Author: Chang, Hang-Lung|Chen, Chih-Yu|Hsu, Ya-Fen|Kuo, Wen-Shin|Ou, George|Chiu, Pei-Ting|Huang, Yu-Han|Hsu, Ming-Jen
PMID: 23583370
Journal: Neoplasia. 2013 May;15(5):481-90.
Title: Multitargeted low-dose GLAD combination chemoprevention: a novel and promising approach to combat colon carcinogenesis.
Author: Mohammed, Altaf|Janakiram, Naveena B|Brewer, Misty|Vedala, Krishna|Steele, Vernon E|Rao, Chinthalapally V
PMID: 23633920
Journal: Mol Biol Cell. 2013 Jun;24(12):1852-62.
Title: Inhibition of nuclear factor-erythroid 2-related factor (Nrf2) by caveolin-1 promotes stress-induced premature senescence.
Author: Volonte, Daniela|Liu, Zhongmin|Musille, Paul M|Stoppani, Elena|Wakabayashi, Nobunao|Di, Yuan-Pu|Lisanti, Michael P|Kensler, Thomas W|Galbiati, Ferruccio
PMID: 23637463
Journal: Int J Biochem Cell Biol. 2013 Aug;45(8):1568-76.
Title: EVI1 targets DeltaNp63 and upregulates the cyclin dependent kinase inhibitor p21 independent of p53 to delay cell cycle progression and cell proliferation in colon cancer cells.
Author: Nayak, Kasturi Bala|Kuila, Nivedita|Das Mohapatra, Alok|Panda, Aditya K|Chakraborty, Soumen
PMID: 23665236
Journal: Int J Biol Sci. 2013 Apr 29;9(4):403-11.
Title: A novel aurora-A inhibitor, BPR1K0609S1, sensitizes colorectal tumor cells to 5-fluorofracil (5-FU) treatment.
Author: Shionome, Yoshimi|Lin, Wen-Hsing|Shiao, Hui-Yi|Hsieh, Hsing-Pang|Hsu, John Tsu-An|Ouchi, Toru
PMID: 23678290
Journal: Int J Oncol. 2013 Jul;43(1):289-96.
Title: Genistein induces G2/M cell cycle arrest and apoptosis via ATM/p53-dependent pathway in human colon cancer cells.
Author: Zhang, Zhiyu|Wang, Chong-Zhi|Du, Guang-Jian|Qi, Lian-Wen|Calway, Tyler|He, Tong-Chuan|Du, Wei|Yuan, Chun-Su
PMID: 23686257
Journal: Mol Cancer Res. 2013 Sep;11(9):1051-60.
Title: Tumor suppressor functions of miR-133a in colorectal cancer.
Author: Dong, Yujuan|Zhao, Junhong|Wu, Chung-Wah|Zhang, Lijing|Liu, Xiaodong|Kang, Wei|Leung, Wing-Wah|Zhang, Ning|Chan, Francis K L|Sung, Joseph J Y|Ng, Simon S M|Yu, Jun
PMID: 23723074
Journal: Mol Cancer Res. 2013 Sep;11(9):1040-50.
Title: Epithelial-specific deletion of 11beta-HSD2 hinders Apcmin/+ mouse tumorigenesis.
Author: Jiang, Li|Yang, Shilin|Yin, Huiyong|Fan, Xiaofeng|Wang, Suwan|Yao, Bing|Pozzi, Ambra|Chen, Xiaoping|Harris, Raymond C|Zhang, Ming-Zhi
PMID: 23741059
Journal: BMC Complement Altern Med. 2013 Jun 8;13:128.
Title: Teng-Long-Bu-Zhong-Tang, a Chinese herbal formula, enhances anticancer effects of 5--Fluorouracil in CT26 colon carcinoma.
Author: Deng, Shan|Hu, Bing|An, Hong-Mei|Du, Qin|Xu, Ling|Shen, Ke-Ping|Shi, Xiu-Feng|Wei, Meng-Meng|Wu, Yang
PMID: 23758730
Journal: Food Chem. 2013 Nov 1;141(1):381-8.
Title: Coumestrol induces senescence through protein kinase CKII inhibition-mediated reactive oxygen species production in human breast cancer and colon cancer cells.
Author: Lee, Young-Hoon|Yuk, Heung Joo|Park, Ki-Hun|Bae, Young-Seuk
PMID: 23768371
Journal: Neoplasia. 2013 Jul;15(7):783-94.
Title: Functional role and therapeutic potential of the pim-1 kinase in colon carcinoma.
Author: Weirauch, Ulrike|Beckmann, Nadine|Thomas, Maren|Grunweller, Arnold|Huber, Kilian|Bracher, Franz|Hartmann, Roland K|Aigner, Achim
PMID: 23814490
Journal: Clin Cancer Res. 2013 Sep 1;19(17):4662-72.
Title: microRNA-224 promotes cell proliferation and tumor growth in human colorectal cancer by repressing PHLPP1 and PHLPP2.
Author: Liao, Wen-Ting|Li, Ting-Ting|Wang, Zheng-Gen|Wang, Shu-Yang|He, Mei-Rong|Ye, Ya-Ping|Qi, Lu|Cui, Yan-Mei|Wu, Ping|Jiao, Hong-Li|Zhang, Chi|Xie, Yi-Jun|Wang, Jun-Xian|Ding, Yan-Qing
PMID: 23846336
Journal: BMC Complement Altern Med. 2013 Jul 24;13:189.
Title: Particled Mica, STB-HO has chemopreventive potential via G1 arrest, and inhibition of proliferation and vascular endothelial growth factor receptor 2 in HCT colorectal cancer cells.
Author: Cho, Sung-Yun|Lee, Hyo-Jeong|Cho, Sun-Mi|Kim, Bonglee|Jung, Yeon Kwon|Kim, Sung-Hoon
PMID: 23883349
Journal: Zhonghua Zhong Liu Za Zhi. 2013 Apr;35(4):249-55.
Title: [Abnormal expression of APRIL in colorectal cancer cells promotes tumor growth and metastasis].
Author: Wang, Gui-hua|Lu, Mei-hong|Wang, Jing-chun|Wang, Feng|Ding, Wei-feng|Wang, Yue-guo|Ju, Shao-qing|Wang, Hui-min
PMID: 23985251
Journal: PLoS One. 2013 Sep 5;8(9):e73466.
Title: CysLT(1)R antagonists inhibit tumor growth in a xenograft model of colon cancer.
Author: Savari, Sayeh|Liu, Minghui|Zhang, Yuan|Sime, Wondossen|Sjolander, Anita
PMID: 24039952
Journal: Biotechnol Lett. 2013 Dec;35(12):2031-8.
Title: Plant-derived mAbs have effective anti-cancer activities by increasing ganglioside expression in colon cancers.
Author: Ryu, Jae-Sung|Lee, Ju-Taek|Lim, Malg-Um|Hwang, Mi-Ran|Hwang, Kyung-A|Cho, Young-Ho|Lee, Jeong-Hwan|Ko, Kisung|Choo, Young-Kug
PMID: 24078119
Journal: Int J Oncol. 2013 Dec;43(6):1925-34.
Title: Differential BCCIP gene expression in primary human ovarian cancer, renal cell carcinoma and colorectal cancer tissues.
Author: Liu, Xiaoxia|Cao, Lingling|Ni, Jinsong|Liu, Ning|Zhao, Xiaoming|Wang, Yanfang|Zhu, Lin|Wang, Lingyao|Wang, Jin|Yue, Ying|Cai, Yong|Jin, Jingji
PMID: 24101097
Journal: Cell Prolif. 2013 Dec;46(6):665-76.
Title: Higher anti-tumour efficacy of platinum(IV) complex LA-12 is associated with its ability to bypass M-phase entry block induced in oxaliplatin-treated human colon cancer cells.
Author: Vondalova Blanarova, O|Jelinkova, I|Hyrslova Vaculova, A|Sova, P|Hofmanova, J|Kozubik, A
PMID: 24118195
Journal: Mol Med Rep. 2013 Dec;8(6):1630-4.
Title: CIZ1 regulates the proliferation, cycle distribution and colony formation of RKO human colorectal cancer cells.
Author: Yin, Jing|Wang, Changliang|Tang, Xiaoyong|Sun, Huaibin|Shao, Qianqian|Yang, Xigui|Qu, Xun
PMID: 24126760
Journal: Cell Death Dis. 2013 Dec 12;4:e963.
Title: PATZ1 interacts with p53 and regulates expression of p53-target genes enhancing apoptosis or cell survival based on the cellular context.
Author: Valentino, T|Palmieri, D|Vitiello, M|Pierantoni, G M|Fusco, A|Fedele, M
PMID: 24336083
Journal: Mol Carcinog. 2014 Feb;53 Suppl 1:E72-84.
Title: The role of ERK2 in colorectal carcinogenesis is partly regulated by TRAPPC4.
Author: Weng, Yu-Rong|Kong, Xuan|Yu, Ya-Nan|Wang, Ying-Chao|Hong, Jie|Zhao, Shu-Liang|Fang, Jing-Yuan
PMID: 23625650
Journal: Int J Oncol. 2014 Jan;44(1):256-64.
Title: A novel hydroxamic acid derivative, MHY218, induces apoptosis and cell cycle arrest through downregulation of NF-kappaB in HCT116 human colon cancer cells.
Author: Kim, Mi Kyeong|Kang, Yong Jung|Kim, Dong Hwan|Hossain, Mohammad Akbar|Jang, Jung Yoon|Lee, Sun Hwa|Yoon, Jeong-Hyun|Chun, Pusoon|Moon, Hyung Ryong|Kim, Hyung Sik|Chung, Hae Young|Kim, Nam Deuk
PMID: 24190633
Journal: Integr Cancer Ther. 2014 May;13(3):240-8.
Title: Scutellaria Barbata D Don Inhibits Colorectal Cancer Growth via Suppression of Multiple Signaling Pathways.
Author: Lin, Jiumao|Chen, Youqin|Cai, Qiaoyan|Wei, Lihui|Zhan, Youzhi|Shen, Aling|Sferra, Thomas J|Peng, Jun
PMID: 24231788
Journal: Apoptosis. 2014 Mar;19(3):451-66.
Title: Cyclin-dependent kinases regulate apoptosis of intestinal epithelial cells.
Author: Bhattacharya, Sujoy|Ray, Ramesh M|Johnson, Leonard R
PMID: 24242917
Journal: Cell Oncol (Dordr). 2014 Feb;37(1):17-28.
Title: Thymidylate synthase expression and p21(WAF1)/p53 phenotype of colon cancers identify patients who may benefit from 5-fluorouracil based therapy.
Author: Sulzyc-Bielicka, Violetta|Domagala, Pawel|Bielicki, Dariusz|Safranow, Krzysztof|Domagala, Wenancjusz
PMID: 24277474
Journal: Life Sci. 2014 Mar 3;97(2):116-22.
Title: Premature senescence in human breast cancer and colon cancer cells by tamoxifen-mediated reactive oxygen species generation.
Author: Lee, Young-Hoon|Kang, Beom Sik|Bae, Young-Seuk
PMID: 24361399
Journal: Mol Cancer Res. 2014 Mar;12(3):348-58.
Title: T-type Ca2+ channel inhibition induces p53-dependent cell growth arrest and apoptosis through activation of p38-MAPK in colon cancer cells.
Author: Dziegielewska, Barbara|Brautigan, David L|Larner, James M|Dziegielewski, Jaroslaw
PMID: 24362252
Journal: Mol Med Rep. 2014 Mar;9(3):941-6.
Title: MiR224 promotes colorectal cancer cells proliferation via downregulation of P21WAF1/CIP1.
Author: Zhang, Xiumei|Zhang, Xia|Liu, Chao|Jia, Ning|Li, Xinyu|Xiao, Jianying
PMID: 24430932
Journal: Oncol Rep. 2014 Apr;31(4):1788-94.
Title: Tangeretin, a citrus polymethoxyflavonoid, induces apoptosis of human gastric cancer AGS cells through extrinsic and intrinsic signaling pathways.
Author: Dong, Yang|Cao, Aili|Shi, Jianrong|Yin, Peihao|Wang, Li|Ji, Guang|Xie, Jianqun|Wu, Dazheng
PMID: 24573532
Journal: Int J Oncol. 2014 May;44(5):1599-606.
Title: Apigenin-induced apoptosis is enhanced by inhibition of autophagy formation in HCT116 human colon cancer cells.
Author: Lee, Yujin|Sung, Bokyung|Kang, Yong Jung|Kim, Dong Hwan|Jang, Jung-Yoon|Hwang, Seong Yeon|Kim, Minjung|Lim, Hyun Sook|Yoon, Jeong-Hyun|Chung, Hae Young|Kim, Nam Deuk
PMID: 24626522
Journal: Oncol Rep. 2014 May;31(5):2371-6.
Title: Vitamin B(6) activates p53 and elevates p21 gene expression in cancer cells and the mouse colon.
Author: Zhang, Peipei|Suidasari, Sofya|Hasegawa, Tomomi|Yanaka, Noriyuki|Kato, Norihisa
PMID: 24626782
Journal: Biochim Biophys Acta. 2014 Jul;1840(7):2361-72.
Title: Cladosporol A, a new peroxisome proliferator-activated receptor gamma (PPARgamma) ligand, inhibits colorectal cancer cells proliferation through beta-catenin/TCF pathway inactivation.
Author: Zurlo, Diana|Assante, Gemma|Moricca, Salvatore|Colantuoni, Vittorio|Lupo, Angelo
PMID: 24735796
Journal: Oncol Res. 2014;21(5):247-59.
Title: Clove extract inhibits tumor growth and promotes cell cycle arrest and apoptosis.
Author: Liu, Haizhou|Schmitz, John C|Wei, Jianteng|Cao, Shousong|Beumer, Jan H|Strychor, Sandra|Cheng, Linyou|Liu, Ming|Wang, Cuicui|Wu, Ning|Zhao, Xiangzhong|Zhang, Yuyan|Liao, Joshua|Chu, Edward|Lin, Xiukun
PMID: 24854101
Journal: Mol Cancer. 2014 May 26;13:124.
Title: microRNA-139-5p exerts tumor suppressor function by targeting NOTCH1 in colorectal cancer.
Author: Zhang, Lijing|Dong, Yujuan|Zhu, Nana|Tsoi, Ho|Zhao, Zengren|Wu, Chung Wah|Wang, Kunning|Zheng, Shu|Ng, Simon Sm|Chan, Francis Kl|Sung, Joseph Jy|Yu, Jun
PMID: 24885920
Journal: Bioorg Med Chem Lett. 2014 Aug 1;24(15):3638-40.
Title: Halogenated diarylacetylenes repress c-myc expression in cancer cells.
Author: Sviripa, Vitaliy M|Zhang, Wen|Kril, Liliia M|Liu, Alice X|Yuan, Yaxia|Zhan, Chang-Guo|Liu, Chunming|Watt, David S
PMID: 24930834
Journal: Autophagy. 2014 Aug;10(8):1403-14.
Title: Combined autophagy and HDAC inhibition: a phase I safety, tolerability, pharmacokinetic, and pharmacodynamic analysis of hydroxychloroquine in combination with the HDAC inhibitor vorinostat in patients with advanced solid tumors.
Author: Mahalingam, Devalingam|Mita, Monica|Sarantopoulos, John|Wood, Leslie|Amaravadi, Ravi K|Davis, Lisa E|Mita, Alain C|Curiel, Tyler J|Espitia, Claudia M|Nawrocki, Steffan T|Giles, Francis J|Carew, Jennifer S
PMID: 24991835
Journal: J Med Food. 2014 Aug;17(8):833-41.
Title: Kimchi protects against azoxymethane/dextran sulfate sodium-induced colorectal carcinogenesis in mice.
Author: Kim, Hee-Young|Song, Jia-Le|Chang, Hee-Kyung|Kang, Soon-Ah|Park, Kun-Young
PMID: 25029638
Journal: Mol Med Rep. 2014 Oct;10(4):1697-702.
Title: Resveratrol inhibits proliferation in human colorectal carcinoma cells by inducing G1/Sphase cell cycle arrest and apoptosis through caspase/cyclinCDK pathways.
Author: Liu, Bin|Zhou, Zhongyou|Zhou, Wei|Liu, Jie|Zhang, Qingyu|Xia, Juan|Liu, Juntao|Chen, Nianping|Li, Mingyi|Zhu, Runzhi
PMID: 25050564
Journal: FEBS Lett. 2014 Aug 25;588(17):3251-8.
Title: Phospholipase D2 downregulation induces cellular senescence through a reactive oxygen species-p53-p21Cip1/WAF1 pathway.
Author: Lee, Young-Hoon|Bae, Young-Seuk
PMID: 25064843
Journal: Mol Cancer Ther. 2014 Oct;13(10):2303-14.
Title: The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth.
Author: Arensman, Michael D|Telesca, Donatello|Lay, Anna R|Kershaw, Kathleen M|Wu, Nanping|Donahue, Timothy R|Dawson, David W
PMID: 25082960
Journal: Cancer Prev Res (Phila). 2014 Aug;7(8):786-95.
Title: Dietary manipulation of oncogenic microRNA expression in human rectal mucosa: a randomized trial.
Author: Humphreys, Karen J|Conlon, Michael A|Young, Graeme P|Topping, David L|Hu, Ying|Winter, Jean M|Bird, Anthony R|Cobiac, Lynne|Kennedy, Nicholas A|Michael, Michael Z|Le Leu, Richard K
PMID: 25092886
Journal: Mol Cells. 2014 Aug;37(8):620-7.
Title: Upregulation of miR-760 and miR-186 is associated with replicative senescence in human lung fibroblast cells.
Author: Lee, Young-Hoon|Kim, Soo Young|Bae, Young-Seuk
PMID: 25139266
Journal: J Microbiol Biotechnol. 2014 Dec 28;24(12):1654-63.
Title: Tumor suppressor protein p53 promotes 2-methoxyestradiol-induced activation of Bak and Bax, leading to mitochondria-dependent apoptosis in human colon cancer HCT116 cells.
Author: Lee, Ji Young|Jee, Su Bean|Park, Won Young|Choi, Yu Jin|Kim, Bokyung|Kim, Yoon Hee|Jun, Do Youn|Kim, Young Ho
PMID: 25179905
Journal: Acta Biochim Biophys Sin (Shanghai). 2014 Oct;46(10):877-84.
Title: Fucoxanthin induces growth arrest and apoptosis in human bladder cancer T24 cells by up-regulation of p21 and down-regulation of mortalin.
Author: Wang, Linbo|Zeng, Yang|Liu, Ye|Hu, Xuansheng|Li, Shuhong|Wang, Yuepeng|Li, Ling|Lei, Zhongfang|Zhang, Zhenya
PMID: 25187415
Journal: J Carcinog. 2014 Jul 29;13:9.
Title: Doenjang prepared with mixed starter cultures attenuates azoxymethane and dextran sulfate sodium-induced colitis-associated colon carcinogenesis in mice.
Author: Jeong, Ji-Kang|Chang, Hee-Kyung|Park, Kun-Young
PMID: 25191137
Journal: Nucleic Acids Res. 2014 Oct;42(18):11447-61.
Title: Two ZNF509 (ZBTB49) isoforms induce cell-cycle arrest by activating transcription of p21/CDKN1A and RB upon exposure to genotoxic stress.
Author: Jeon, Bu-Nam|Kim, Min-Kyeong|Yoon, Jae-Hyeon|Kim, Min-Young|An, Haemin|Noh, Hee-Jin|Choi, Won-Il|Koh, Dong-In|Hur, Man-Wook
PMID: 25245946
Journal: Sci Signal. 2014 Sep 30;7(345):ra92.
Title: Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-beta-catenin-mediated intestinal tumor growth and regeneration.
Author: Phesse, Toby J|Buchert, Michael|Stuart, Emma|Flanagan, Dustin J|Faux, Maree|Afshar-Sterle, Shoukat|Walker, Francesca|Zhang, Hui-Hua|Nowell, Cameron J|Jorissen, Robert|Tan, Chin Wee|Hirokawa, Yumiko|Eissmann, Moritz F|Poh, Ashleigh R|Malaterre, Jordane|Pea
PMID: 25270258
Journal: Anticancer Res. 2014 Oct;34(10):5439-46.
Title: Resveratrol enhances mitomycin C-mediated suppression of human colorectal cancer cell proliferation by up-regulation of p21WAF1/CIP1.
Author: Ali, Irshad|Braun, Donald P
PMID: 25275039
Journal: Zhonghua Zhong Liu Za Zhi. 2014 Jul;36(7):496-500.
Title: [Effects of small interfering RNA silencing MACC-1 expression on cell proliferation, cell cycle and invasion ability of cervical cancer SiHa cells].
Author: Hua, Fangfang|Xia, Yonghua|Wang, Huiling|Chen, Ruixiang|Ren, Yanfang|Yang, Jun|Liang, Wufeng
PMID: 25327653
Journal: World J Gastroenterol. 2014 Nov 7;20(41):15275-88.
Title: Differential control of growth, apoptotic activity and gene expression in human colon cancer cells by extracts derived from medicinal herbs, Rhazya stricta and Zingiber officinale and their combination.
Author: Elkady, Ayman I|Hussein, Rania Abd El Hamid|Abu-Zinadah, Osama A
PMID: 25386076
Journal: Biomed Pharmacother. 2014 Oct;68(8):1089-97.
Title: Down-regulation of sphingosine kinase 2 (SphK2) increases the effects of all-trans-retinoic acid (ATRA) on colon cancer cells.
Author: Chu, Jia-Hui|Gao, Zu-Hua|Qu, Xian-Jun
PMID: 25455157
Journal: Oncoimmunology. 2014 Nov 14;3(8):e952202.
Title: Anti-p21 autoantibodies detected in colorectal cancer patients: A proof of concept study.
Author: Bishehsari, Faraz|Gach, Johannes S|Akagi, Naomi|Webber, Molly K|Bauer, Jessica|Jung, Barbara H
PMID: 25960931
Journal: Mol Carcinog. 2015 Oct;54(10):1070-85.
Title: Piperine, an alkaloid from black pepper, inhibits growth of human colon cancer cells via G1 arrest and apoptosis triggered by endoplasmic reticulum stress.
Author: Yaffe, Paul B|Power Coombs, Melanie R|Doucette, Carolyn D|Walsh, Mark|Hoskin, David W
PMID: 24819444
Journal: Mol Carcinog. 2015 Nov;54(11):1442-50.
Title: MiR-96-5p influences cellular growth and is associated with poor survival in colorectal cancer patients.
Author: Ress, Anna Lena|Stiegelbauer, Verena|Winter, Elke|Schwarzenbacher, Daniela|Kiesslich, Tobias|Lax, Sigurd|Jahn, Stefan|Deutsch, Alexander|Bauernhofer, Thomas|Ling, Hui|Samonigg, Hellmut|Gerger, Armin|Hoefler, Gerald|Pichler, Martin
PMID: 25256312
Journal: Cancer Lett. 2015 Jan 28;356(2 Pt B):637-45.
Title: AK-1, a specific SIRT2 inhibitor, induces cell cycle arrest by downregulating Snail in HCT116 human colon carcinoma cells.
Author: Cheon, Min Gyeong|Kim, Wootae|Choi, Minji|Kim, Ja-Eun
PMID: 25312940
Journal: Ann Surg Oncol. 2015 Dec;22 Suppl 3:S1394-401.
Title: A Cancer Reprogramming Method Using MicroRNAs as a Novel Therapeutic Approach against Colon Cancer: Research for Reprogramming of Cancer Cells by MicroRNAs.
Author: Miyazaki, Susumu|Yamamoto, Hirofumi|Miyoshi, Norikatsu|Wu, Xin|Ogawa, Hisataka|Uemura, Mamoru|Nishimura, Junichi|Hata, Taishi|Takemasa, Ichiro|Mizushima, Tsunekazu|Konno, Masamitsu|Doki, Yuichiro|Mori, Masaki|Ishii, Hideshi
PMID: 25384704
Journal: Int J Oncol. 2015 Feb;46(2):732-40.
Title: Downregulation of Msi1 suppresses the growth of human colon cancer by targeting p21cip1.
Author: Gao, Chao|Han, Chun|Yu, Qiyao|Guan, Yue|Li, Na|Zhou, Jingjing|Tian, Yanming|Zhang, Yi
PMID: 25394506
Journal: Cancer Chemother Pharmacol. 2015 Feb;75(2):411-20.
Title: Cks1 proteasomal degradation is induced by inhibiting Hsp90-mediated chaperoning in cancer cells.
Author: Khattar, Vinayak|Fried, Joshua|Xu, Bo|Thottassery, Jaideep V
PMID: 25544127
Journal: Mar Drugs. 2015 Jan 16;13(1):543-57.
Title: Activation of p53 with ilimaquinone and ethylsmenoquinone, marine sponge metabolites, induces apoptosis and autophagy in colon cancer cells.
Author: Lee, Hyun-Young|Chung, Kyu Jin|Hwang, In Hyun|Gwak, Jungsuk|Park, Seoyoung|Ju, Bong Gun|Yun, Eunju|Kim, Dong-Eun|Chung, Young-Hwa|Na, MinKyun|Song, Gyu-Yong|Oh, Sangtaek
PMID: 25603347
Journal: Int J Oncol. 2015 Apr;46(4):1788-800.
Title: Generation of an anti-EpCAM antibody and epigenetic regulation of EpCAM in colorectal cancer.
Author: Liao, Mei-Ying|Kuo, Mark Yen-Ping|Lu, Tung-Ying|Wang, Yi-Ping|Wu, Han-Chung
PMID: 25652097
Journal: J Natl Cancer Inst. 2015 Feb 6;107(4). pii: dju505.
Title: Role of MYC-regulated long noncoding RNAs in cell cycle regulation and tumorigenesis.
Author: Kim, Taewan|Jeon, Young-Jun|Cui, Ri|Lee, Ji-Hoon|Peng, Yong|Kim, Sung-Hak|Tili, Esmerina|Alder, Hansjuerg|Croce, Carlo M
PMID: 25663692
Journal: Oncol Res. 2015;22(2):93-103.
Title: RNA interference of Biot2 induces G1 phase arrest and apoptosis in mouse colorectal cancer cell line.
Author: Zhou, Cong|Zhang, Peng|Xu, Guang-Chao|Wu, Dong-Ming|Liu, Ru-Yan|Zeng, Qi|Wang, Chun-Ting
PMID: 25706396
Journal: J Cancer. 2015 Feb 15;6(4):342-50.
Title: Grainyhead-like 2 Promotes Tumor Growth and is Associated with Poor Prognosis in Colorectal Cancer.
Author: Quan, Yingjun|Xu, Ming|Cui, Peng|Ye, Min|Zhuang, Biao|Min, Zhijun
PMID: 25767604
Journal: Cell Cycle. 2015;14(10):1517-28.
Title: Phosphorylation-dependent degradation of MEF2C contributes to regulate G2/M transition.
Author: Badodi, Sara|Baruffaldi, Fiorenza|Ganassi, Massimo|Battini, Renata|Molinari, Susanna
PMID: 25789873
Journal: Gastroenterology. 2015 Jul;149(1):177-189.e10.
Title: VEGFR2 Signaling Prevents Colorectal Cancer Cell Senescence to Promote Tumorigenesis in Mice With Colitis.
Author: Foersch, Sebastian|Sperka, Tobias|Lindner, Christina|Taut, Astrid|Rudolph, Karl L|Breier, Georg|Boxberger, Frank|Rau, Tilman T|Hartmann, Arndt|Sturzl, Michael|Wittkopf, Nadine|Haep, Lisa|Wirtz, Stefan|Neurath, Markus F|Waldner, Maximilian J
PMID: 25797700
Journal: PLoS One. 2015 Mar 23;10(3):e0119649.
Title: Association between GWAS-identified genetic variations and disease prognosis for patients with colorectal cancer.
Author: Kang, Byung Woog|Jeon, Hyo-Sung|Chae, Yee Soo|Lee, Soo Jung|Park, Jae Yong|Choi, Jin Eun|Park, Jun Seok|Choi, Gyu Seog|Kim, Jong Gwang
PMID: 25799222
Journal: Mutagenesis. 2015 Jul;30(4):565-76.
Title: Inhibition of beta-catenin signalling promotes DNA damage elicited by benzo[a]pyrene in a model of human colon cancer cells via CYP1 deregulation.
Author: Kabatkova, Marketa|Zapletal, Ondrej|Tylichova, Zuzana|Neca, Jiri|Machala, Miroslav|Milcova, Alena|Topinka, Jan|Kozubik, Alois|Vondracek, Jan
PMID: 25805023
Journal: Free Radic Biol Med. 2015 Aug;85:105-13.
Title: P53-dependent miRNAs mediate nitric oxide-induced apoptosis in colonic carcinogenesis.
Author: Li, Weiwei|Han, Wenxiao|Ma, Yiming|Cui, Liang|Tian, Yantao|Zhou, Zhixiang|Wang, Hongying
PMID: 25912478
Journal: Mol Oncol. 2015 Aug;9(7):1406-20.
Title: Natural product (-)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1.
Author: Lan, Lan|Appelman, Carl|Smith, Amber R|Yu, Jia|Larsen, Sarah|Marquez, Rebecca T|Liu, Hao|Wu, Xiaoqing|Gao, Philip|Roy, Anuradha|Anbanandam, Asokan|Gowthaman, Ragul|Karanicolas, John|De Guzman, Roberto N|Rogers, Steven|Aube, Jeffrey|Ji, Min|Cohen, Robert S
PMID: 25933687
Journal: BMC Cancer. 2015 May 10;15:391.
Title: NBPF1, a tumor suppressor candidate in neuroblastoma, exerts growth inhibitory effects by inducing a G1 cell cycle arrest.
Author: Andries, Vanessa|Vandepoele, Karl|Staes, Katrien|Berx, Geert|Bogaert, Pieter|Van Isterdael, Gert|Ginneberge, Daisy|Parthoens, Eef|Vandenbussche, Jonathan|Gevaert, Kris|van Roy, Frans
PMID: 25958384
Journal: J Cell Physiol. 2015 Dec;230(12):3105-14.
Title: The Effects of miR-20a on p21: Two Mechanisms Blocking Growth Arrest in TGF-beta-Responsive Colon Carcinoma.
Author: Sokolova, Viktorija|Fiorino, Antonio|Zoni, Eugenio|Crippa, Elisabetta|Reid, James F|Gariboldi, Manuela|Pierotti, Marco A
PMID: 26012475
Journal: Oncotarget. 2015 Aug 28;6(25):21064-73.
Title: High RAD54B expression: an independent predictor of postoperative distant recurrence in colorectal cancer patients.
Author: Nagai, Yuzo|Yamamoto, Yoko|Yasuhara, Takaaki|Hata, Keisuke|Nishikawa, Takeshi|Tanaka, Toshiaki|Tanaka, Junichiro|Kiyomatsu, Tomomichi|Kawai, Kazushige|Nozawa, Hiroaki|Kazama, Shinsuke|Yamaguchi, Hironori|Ishihara, Soichiro|Sunami, Eiji|Yamanaka, Takeharu|
PMID: 26046797
Journal: Sci Rep. 2015 Jun 9;5:11187.
Title: Folic acid inhibits COLO-205 colon cancer cell proliferation through activating the FRalpha/c-SRC/ERK1/2/NFkappaB/TP53 pathway: in vitro and in vivo studies.
Author: Kuo, Chun-Ting|Chang, Chieh|Lee, Wen-Sen
PMID: 26056802
Journal: Am J Chin Med. 2015;43(4):743-56.
Title: Anti-Colon Cancer Effects of 6-Shogaol Through G2/M Cell Cycle Arrest by p53/p21-cdc2/cdc25A Crosstalk.
Author: Qi, Lian-Wen|Zhang, Zhiyu|Zhang, Chun-Feng|Anderson, Samantha|Liu, Qun|Yuan, Chun-Su|Wang, Chong-Zhi
PMID: 26119958
Journal: Oncol Rep. 2015 Sep;34(3):1178-84.
Title: Widdrol, a sesquiterpene isolated from Juniperus chinensis, inhibits angiogenesis by targeting vascular endothelial growth factor receptor 2 signaling.
Author: Jin, Soojung|Yun, Hee Jung|Jeong, Hyun Young|Oh, You Na|Park, Hyun-Jin|Yun, Seung-Geun|Kim, Byung Woo|Kwon, Hyun Ju
PMID: 26133679
Journal: Int J Cancer. 2015 Dec 15;137(12):2803-14.
Title: Inflammation-induced S100A8 activates Id3 and promotes colorectal tumorigenesis.
Author: Zhang, Xuemei|Ai, Feiyan|Li, Xiayu|She, Xiaoling|Li, Nan|Tang, Anliu|Qin, Zailong|Ye, Qiurong|Tian, Li|Li, Guiyuan|Shen, Shourong|Ma, Jian
PMID: 26135667
Journal: Cancer Res. 2015 Nov 1;75(21):4593-604.
Title: Heterochromatin protein HP1gamma promotes colorectal cancer progression and is regulated by miR-30a.
Author: Liu, Ming|Huang, Feifei|Zhang, Dan|Ju, Junyi|Wu, Xiao-Bin|Wang, Ying|Wang, Yadong|Wu, Yupeng|Nie, Min|Li, Zhuchen|Ma, Chi|Chen, Xi|Zhou, Jin-Yong|Tan, Renxiang|Yang, Bo-Lin|Zen, Ke|Zhang, Chen-Yu|Chen, Yu-Gen|Zhao, Quan
PMID: 26333808
Journal: Cell Physiol Biochem. 2015;37(3):1044-54.
Title: MiR-423-3p enhances cell growth through inhibition of p21Cip1/Waf1 in colorectal cancer.
Author: Li, Hong-Tao|Zhang, Hui|Chen, Yong|Liu, Xian-Fu|Qian, Jun
PMID: 26402653
Journal: Mol Med Rep. 2015 Nov;12(5):7538-44.
Title: Knockdown of biglycan expression by RNA interference inhibits the proliferation and invasion of, and induces apoptosis in, the HCT116 colon cancer cell line.
Author: Xing, Xiaojing|Gu, Xiaohu|Ma, Tianfei
PMID: 26459740
Journal: Int J Oncol. 2015 Dec;47(6):2247-54.
Title: Oleanolic acid modulates multiple intracellular targets to inhibit colorectal cancer growth.
Author: Li, Li|Wei, Lihui|Shen, Aling|Chu, Jianfeng|Lin, Jiumao|Peng, Jun
PMID: 26459864
Journal: Mol Cancer. 2015 Oct 24;14:182.
Title: Activin and TGFbeta use diverging mitogenic signaling in advanced colon cancer.
Author: Bauer, Jessica|Ozden, Ozkan|Akagi, Naomi|Carroll, Timothy|Principe, Daniel R|Staudacher, Jonas J|Spehlmann, Martina E|Eckmann, Lars|Grippo, Paul J|Jung, Barbara
PMID: 26497569
Journal: Oncotarget. 2015 Nov 10;6(35):37852-70.
Title: miRNA-regulated delivery of lincRNA-p21 suppresses beta-catenin signaling and tumorigenicity of colorectal cancer stem cells.
Author: Wang, Jun|Lei, Zeng-jie|Guo, Yan|Wang, Tao|Qin, Zhong-yi|Xiao, Hua-liang|Fan, Li-lin|Chen, Dong-feng|Bian, Xiu-wu|Liu, Jia|Wang, Bin
PMID: 26497997
Journal: Sci Rep. 2015 Oct 29;5:15900.
Title: The effects of a novel aliphatic-chain hydroxamate derivative WMJ-S-001 in HCT116 colorectal cancer cell death.
Author: Huang, Yu-Han|Huang, Shiu-Wen|Hsu, Ya-Fen|Ou, George|Huang, Wei-Jan|Hsu, Ming-Jen
PMID: 26510776
Journal: Mol Carcinog. 2016 Sep;55(9):1355-68.
Title: Atypical role of sprouty in p21 dependent inhibition of cell proliferation in colorectal cancer.
Author: Zhang, Qiong|Shim, Katherine|Wright, Kevin|Jurkevich, Alexander|Khare, Sharad
PMID: 26293890
Journal: Nucleic Acids Res. 2016 Jan 29;44(2):582-94.
Title: LRH-1 drives colon cancer cell growth by repressing the expression of the CDKN1A gene in a p53-dependent manner.
Author: Kramer, Holly B|Lai, Chun-Fui|Patel, Hetal|Periyasamy, Manikandan|Lin, Meng-Lay|Feller, Stephan M|Fuller-Pace, Frances V|Meek, David W|Ali, Simak|Buluwela, Laki
PMID: 26400164
Journal: Tumour Biol. 2016 May;37(5):6007-16.
Title: Aspirin acetylates wild type and mutant p53 in colon cancer cells: identification of aspirin acetylated sites on recombinant p53.
Author: Ai, Guoqiang|Dachineni, Rakesh|Kumar, D Ramesh|Marimuthu, Srinivasan|Alfonso, Lloyd F|Bhat, G Jayarama
PMID: 26596838
Journal: Mol Nutr Food Res. 2016 Apr;60(4):701-16.
Title: Comprehensive characterization of the effects of ellagic acid and urolithins on colorectal cancer and key-associated molecular hallmarks: MicroRNA cell specific induction of CDKN1A (p21) as a common mechanism involved.
Author: Gonzalez-Sarrias, Antonio|Nunez-Sanchez, Maria Angeles|Tome-Carneiro, Joao|Tomas-Barberan, Francisco A|Garcia-Conesa, Maria Teresa|Espin, Juan Carlos
PMID: 26634414
Journal: Cell Cycle. 2016;15(1):41-51.
Title: Regulatory role of rpL3 in cell response to nucleolar stress induced by Act D in tumor cells lacking functional p53.
Author: Russo, Annapina|Pagliara, Valentina|Albano, Francesco|Esposito, Davide|Sagar, Vinay|Loreni, Fabrizio|Irace, Carlo|Santamaria, Rita|Russo, Giulia
PMID: 26636733
Journal: Cancer Res. 2016 Feb 1;76(3):724-35.
Title: Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis.
Author: Marusiak, Anna A|Stephenson, Natalie L|Baik, Hayeon|Trotter, Eleanor W|Li, Yaoyong|Blyth, Karen|Mason, Susan|Chapman, Phil|Puto, Lorena A|Read, Jon A|Brassington, Claire|Pollard, Hannah K|Phillips, Chris|Green, Isabelle|Overman, Ross|Collier, Matthew|Test
PMID: 26637668
Journal: Cell Death Dis. 2016 Jan 28;7:e2074.
Title: Downregulation of CDC27 inhibits the proliferation of colorectal cancer cells via the accumulation of p21Cip1/Waf1.
Author: Qiu, L|Wu, J|Pan, C|Tan, X|Lin, J|Liu, R|Chen, S|Geng, R|Huang, W
PMID: 26821069
Journal: Am J Pathol. 2016 Apr;186(4):1015-24.
Title: Decreasing CNPY2 Expression Diminishes Colorectal Tumor Growth and Development through Activation of p53 Pathway.
Author: Yan, Ping|Gong, Hui|Zhai, Xiaoyan|Feng, Yi|Wu, Jun|He, Sheng|Guo, Jian|Wang, Xiaoxia|Guo, Rui|Xie, Jun|Li, Ren-Ke
PMID: 26835537
Journal: PLoS One. 2016 Feb 9;11(2):e0148775.
Title: Flavokawain C Inhibits Cell Cycle and Promotes Apoptosis, Associated with Endoplasmic Reticulum Stress and Regulation of MAPKs and Akt Signaling Pathways in HCT 116 Human Colon Carcinoma Cells.
Author: Phang, Chung-Weng|Karsani, Saiful Anuar|Sethi, Gautam|Abd Malek, Sri Nurestri
PMID: 26859847
Journal: Oncotarget. 2016 Mar 29;7(13):15915-29.
Title: miR-30e controls DNA damage-induced stress responses by modulating expression of the CDK inhibitor p21WAF1/CIP1 and caspase-3.
Author: Sohn, Dennis|Peters, Dominik|Piekorz, Roland P|Budach, Wilfried|Janicke, Reiner U
PMID: 26895377
Journal: Mol Med Rep. 2016 Apr;13(4):3525-32.
Title: Growth inhibition effects of ent-11alpha-hydroxy-15-oxo-kaur-16-en-19-oic-acid on colorectal carcinoma cells and colon carcinoma-bearing mice.
Author: Ye, Hua|Wu, Qiong|Guo, Meng|Wu, Kefeng|Lv, Yingnian|Yu, Fengyan|Liu, Yi|Gao, Xiaosheng|Zhu, Yuzhen|Cui, Liao|Liang, Nianci|Yun, Tu|Li, Li|Zheng, Xuebao
PMID: 26935771
Journal: Oncol Rep. 2016 May;35(5):2927-35.
Title: Inhibitor of growth 4 suppresses colorectal cancer growth and invasion by inducing G1 arrest, inhibiting tumor angiogenesis and reversing epithelial-mesenchymal transition.
Author: Qu, Hui|Yin, Hong|Yan, Su|Tao, Min|Xie, Yufeng|Chen, Weichang
PMID: 26936485
Journal: Biochem Pharmacol. 2016 May 15;108:22-35.
Title: The antiproliferative and proapoptotic effects of cladosporols A and B are related to their different binding mode as PPARgamma ligands.
Author: Zurlo, Diana|Ziccardi, Pamela|Votino, Carolina|Colangelo, Tommaso|Cerchia, Carmen|Dal Piaz, Fabrizio|Dallavalle, Sabrina|Moricca, Salvatore|Novellino, Ettore|Lavecchia, Antonio|Colantuoni, Vittorio|Lupo, Angelo
PMID: 26995279
Journal: Mol Nutr Food Res. 2016 Jun;60(6):1482-500.
Title: Induction of cell cycle arrest and apoptosis with downregulation of Hsp90 client proteins and histone modification by 4beta-hydroxywithanolide E isolated from Physalis peruviana.
Author: Park, Eun-Jung|Sang-Ngern, Mayuramas|Chang, Leng Chee|Pezzuto, John M
PMID: 27006100
Journal: Oncol Rep. 2016 Jun;35(6):3331-40.
Title: Effect of Recepteur d'Origine Nantais expression on chemosensitivity and tumor cell behavior in colorectal cancer.
Author: Kim, Nuri|Cho, Sung-Bum|Park, Young-Lan|Park, Sun-Young|Myung, Eun|Kim, Seung-Hun|Yu, Hyung-Min|Son, Young-Ae|Myung, Dae-Seong|Lee, Wan-Sik|Joo, Young-Eun
PMID: 27035413
Journal: Oncogenesis. 2016 Apr 4;5:e213.
Title: Ultraconserved region-containing Transformer 2beta4 controls senescence of colon cancer cells.
Author: Kajita, K|Kuwano, Y|Satake, Y|Kano, S|Kurokawa, K|Akaike, Y|Masuda, K|Nishida, K|Rokutan, K
PMID: 27043659
Journal: Chem Biol Interact. 2016 Jun 25;253:112-24.
Title: An appraisal of cinnamyl sulfonamide hydroxamate derivatives (HDAC inhibitors) for anti-cancer, anti-angiogenic and anti-metastatic activities in human cancer cells.
Author: Reddy, Neetinkumar D|Shoja, M H|Biswas, Subhankar|Nayak, Pawan G|Kumar, Nitesh|Rao, C Mallikarjuna
PMID: 27163855
Journal: Oncotarget. 2016 Jul 5;7(27):41540-41558.
Title: EZH2 promotes colorectal cancer stem-like cell expansion by activating p21cip1-Wnt/beta-catenin signaling.
Author: Chen, Jian-Fang|Luo, Xi|Xiang, Li-Sha|Li, Hong-Tao|Zha, Lin|Li, Ni|He, Jian-Ming|Xie, Gan-Feng|Xie, Xiong|Liang, Hou-Jie
PMID: 27172794
Journal: Food Funct. 2016 Jul 13;7(7):3163-75.
Title: Boletus edulis ribonucleic acid - a potent apoptosis inducer in human colon adenocarcinoma cells.
Author: Lemieszek, Marta Kinga|Ribeiro, Miguel|Guichard Alves, Helena|Marques, Guilhermina|Nunes, Fernando Milheiro|Rzeski, Wojciech
PMID: 27302173
Journal: Oncotarget. 2016 Jul 5;7(27):42225-42240.
Title: Hsa-miR-875-5p exerts tumor suppressor function through down-regulation of EGFR in colorectal carcinoma (CRC).
Author: Zhang, Tiening|Cai, Xun|Li, Qi|Xue, Peng|Chen, Zhixiao|Dong, Xiao|Xue, Ying
PMID: 27302926
Journal: Mol Med Rep. 2016 Aug;14(2):1397-403.
Title: Berry anthocyanins reduce proliferation of human colorectal carcinoma cells by inducing caspase-3 activation and p21 upregulation.
Author: Anwar, Sirajudheen|Fratantonio, Deborah|Ferrari, Daniela|Saija, Antonella|Cimino, Francesco|Speciale, Antonio
PMID: 27314273
Journal: Biochem Biophys Res Commun. 2016 Sep 9;478(1):18-24.
Title: Inactivation of the FoxO3a transcription factor is associated with the production of reactive oxygen species during protein kinase CK2 downregulation-mediated senescence in human colon cancer and breast cancer cells.
Author: Park, Seong-Yeol|Bae, Young-Seuk
PMID: 27470586
Journal: PLoS One. 2016 Aug 10;11(8):e0160961.
Title: miR-6734 Up-Regulates p21 Gene Expression and Induces Cell Cycle Arrest and Apoptosis in Colon Cancer Cells.
Author: Kang, Moo Rim|Park, Ki Hwan|Yang, Jeong-Ook|Lee, Chang Woo|Oh, Soo Jin|Yun, Jieun|Lee, Myeong Youl|Han, Sang-Bae|Kang, Jong Soon
PMID: 27509128
Journal: J Med Invest. 2016;63(3-4):219-26.
Title: Serine/arginine-rich splicing factor 7 regulates p21-dependent growth arrest in colon cancer cells.
Author: Saijo, Saki|Kuwano, Yuki|Masuda, Kiyoshi|Nishikawa, Tatsuya|Rokutan, Kazuhito|Nishida, Kensei
PMID: 27644562
Journal: J Exp Clin Cancer Res. 2016 Sep 27;35(1):152.
Title: TLE3 represses colorectal cancer proliferation by inhibiting MAPK and AKT signaling pathways.
Author: Yang, Run-Wei|Zeng, Ying-Yue|Wei, Wen-Ting|Cui, Yan-Mei|Sun, Hui-Ying|Cai, Yue-Long|Nian, Xin-Xin|Hu, Yun-Teng|Quan, Yu-Ping|Jiang, Sheng-Lu|Wang, Meng|Zhao, Ya-Li|Qiu, Jun-Feng|Li, Ming-Xuan|Zhang, Jia-Huan|He, Mei-Rong|Liang, Li|Ding, Yan-Qing|Liao, Wen
PMID: 27669982
Journal: BMC Complement Altern Med. 2016 Oct 1;16(1):384.
Title: Methylferulate from Tamarix aucheriana inhibits growth and enhances chemosensitivity of human colorectal cancer cells: possible mechanism of action.
Author: Abaza, Mohamed Salah I|Afzal, Mohammad|Al-Attiyah, Raja'a J|Guleri, Radhika
PMID: 27716288
Journal: J Agric Food Chem. 2016 Oct 11.
Title: Stereoisomers of Astaxanthin Inhibit Human Colon Cancer Cell Growth by Inducing G2/M Cell Cycle Arrest and Apoptosis.
Author: Liu, Xiaojuan|Song, Mingyue|Gao, Zili|Cai, Xiaokun|Dixon, William|Chen, Xiaofeng|Cao, Yong|Xiao, Hang
PMID: 27726394
Journal: Int J Oncol. 2016 Dec;49(6):2558-2568.
Title: Acquisition of anticancer drug resistance is partially associated with cancer stemness in human colon cancer cells.
Author: El Khoury, Flaria|Corcos, Laurent|Durand, Stephanie|Simon, Brigitte|Le Jossic-Corcos, Catherine
PMID: 27748801
Journal: Oncotarget. 2016 Nov 29;7(48):79017-79031.
Title: ING4 suppresses tumor angiogenesis and functions as a prognostic marker in human colorectal cancer.
Author: Chen, Yansu|Huang, Yefei|Hou, Pingfu|Zhang, Zhe|Zhang, Yafei|Wang, Weimin|Sun, Guixiang|Xu, Lichun|Zhou, Jianwei|Bai, Jin|Zheng, Junnian
PMID: 27806345
Journal: Tumour Biol. 2016 Nov 10. pii: 10.1007/s13277-016-5424-0.
Title: Expression pattern of BCCIP in hepatocellular carcinoma is correlated with poor prognosis and enhanced cell proliferation.
Author: Lin, Zhipeng|Hu, Baoying|Ni, Wenkai|Mao, Xiaofei|Zhou, Huiling|Lv, Jiale|Yin, Bihui|Shen, Zhongyi|Wu, Miaomiao|Ding, Wensen|Xiao, Mingbing|Ni, Runzhou
PMID: 27832471
Journal: J Med Food. 2016 Nov;19(11):1015-1022.
Title: Bamboo Salt Suppresses Colon Carcinogenesis in C57BL/6 Mice with Chemically Induced Colitis.
Author: Ju, Jaehyun|Lee, Ga-Young|Kim, Yoon-Se|Chang, Hee Kyung|Do, Myoung-Sool|Park, Kun-Young
PMID: 27845862
Journal: J Cancer Prev. 2016 Dec;21(4):249-256.
Title: Sorbus rufopilosa Extract Exhibits Antioxidant and Anticancer Activities by Inducing Cell Cycle Arrest and Apoptosis in Human Colon Adenocarcinoma HT29 Cells.
Author: Oh, You Na|Jin, Soojung|Park, Hyun-Jin|Kwon, Hyun Ju|Kim, Byung Woo
PMID: 28053959
Journal: Mol Carcinog. 2017 Jan;56(1):18-35.
Title: Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor-induced angiogenesis through cell cycle arrest, apoptosis induction and inhibition of VEGF expression.
Author: Zakraoui, Ons|Marcinkiewicz, Cezary|Aloui, Zohra|Othman, Houcemeddine|Grepin, Renaud|Haoues, Meriam|Essafi, Makram|Srairi-Abid, Najet|Gasmi, Ammar|Karoui, Habib|Pages, Gilles|Essafi-Benkhadir, Khadija
PMID: 26824338
Journal: Oncotarget. 2017 Jan 31;8(5):7502-7520.
Title: BTG1 might be employed as a biomarker for carcinogenesis and a target for gene therapy in colorectal cancers.
Author: Zhao, Shuang|Chen, Shu-Rui|Yang, Xue-Feng|Shen, Dao-Fu|Takano, Yasuo|Su, Rong-Jian|Zheng, Hua-Chuan
PMID: 27447746
Journal: Oncotarget. 2017 Jan 3;8(1):364-378.
Title: Epithelial derived-matrix metalloproteinase (MMP9) exhibits a novel defensive role of tumor suppressor in colitis associated cancer by activating MMP9-Notch1-ARF-p53 axis.
Author: Walter, Lewins|Pujada, Adani|Bhatnagar, Noopur|Bialkowska, Agnieszka B|Yang, Vincent W|Laroui, Hamed|Garg, Pallavi
PMID: 27861153
Journal: Environ Toxicol. 2017 Aug;32(8):2041-2052.
Title: Casticin induced apoptotic cell death and altered associated gene expression in human colon cancer colo 205 cells.
Author: Shang, Hung-Sheng|Liu, Jia-You|Lu, Hsu-Feng|Chiang, Han-Sun|Lin, Chia-Hain|Chen, Ann|Lin, Yuh-Feng|Chung, Jing-Gung
PMID: 27862857
Journal: Cell Death Differ. 2017 Mar;24(3):458-468.
Title: Ketogenesis contributes to intestinal cell differentiation.
Author: Wang, Qingding|Zhou, Yuning|Rychahou, Piotr|Fan, Teresa W-M|Lane, Andrew N|Weiss, Heidi L|Evers, B Mark
PMID: 27935584
Journal: Drug Des Devel Ther. 2016 Dec 28;11:103-121.
Title: Anticancer and anti-inflammatory activities of girinimbine isolated from Murraya koenigii.
Author: Iman, Venoos|Mohan, Syam|Abdelwahab, Siddig Ibrahim|Karimian, Hamed|Nordin, Noraziah|Fadaeinasab, Mehran|Noordin, Mohamad Ibrahim|Noor, Suzita Mohd
PMID: 28096658
Journal: Oncogenesis. 2017 Jan 23;6(1):e288.
Title: Long noncoding RNA HOXA-AS2 represses P21 and KLF2 expression transcription by binding with EZH2, LSD1 in colorectal cancer.
Author: Ding, J|Xie, M|Lian, Y|Zhu, Y|Peng, P|Wang, J|Wang, L|Wang, K
PMID: 28112720
Journal: Neoplasia. 2017 Mar;19(3):175-184.
Title: The Heparanase Inhibitor PG545 Attenuates Colon Cancer Initiation and Growth, Associating with Increased p21 Expression.
Author: Singh, Preeti|Blatt, Alexandra|Feld, Sari|Zohar, Yaniv|Saadi, Esraa|Barki-Harrington, Liza|Hammond, Edward|Ilan, Neta|Vlodavsky, Israel|Chowers, Yehuda|Half, Elizabeth
PMID: 28147305
Journal: J Agric Food Chem. 2017 Mar 1;65(8):1566-1573.
Title: Novel ent-Kaurane Diterpenoid from Rubus corchorifolius L. f. Inhibits Human Colon Cancer Cell Growth via Inducing Cell Cycle Arrest and Apoptosis.
Author: Chen, Xuexiang|Wu, Xian|Ouyang, Wen|Gu, Min|Gao, Zili|Song, Mingyue|Chen, Yunjiao|Lin, Yanyin|Cao, Yong|Xiao, Hang
PMID: 28169543
Journal: J Nutr Biochem. 2017 Apr;42:126-133.
Title: Gene expression changes in colon tissues from colorectal cancer patients following the intake of an ellagitannin-containing pomegranate extract: a randomized clinical trial.
Author: Nunez-Sanchez, Maria A|Gonzalez-Sarrias, Antonio|Garcia-Villalba, Rocio|Monedero-Saiz, Tamara|Garcia-Talavera, Noelia V|Gomez-Sanchez, Maria B|Sanchez-Alvarez, Carmen|Garcia-Albert, Ana M|Rodriguez-Gil, Francisco J|Ruiz-Marin, Miguel|Pastor-Quirante, Fran
PMID: 28183047
Journal: Nanotechnology. 2017 Mar 7;28(13):135103.
Title: Preparation of carotenoid extracts and nanoemulsions from Lycium barbarum L. and their effects on growth of HT-29 colon cancer cells.
Author: Hsu, H J|Huang, R F|Kao, T H|Inbaraj, B S|Chen, B H
PMID: 28266352
Journal: Int J Oncol. 2017 May;50(5):1671-1682.
Title: p53-inducible long non-coding RNA PICART1 mediates cancer cell proliferation and migration.
Author: Cao, Yu|Lin, Minglin|Bu, Yiwen|Ling, Hongyan|He, Yingchun|Huang, Chenfei|Shen, Yi|Song, Bob|Cao, Deliang
PMID: 28339031
Journal: J Biol Chem. 2017 May 19;292(20):8331-8341.
Title: The DEAD-box RNA helicase DDX41 is a novel repressor of p21(WAF1/CIP1) mRNA translation.
Author: Peters, Dominik|Radine, Claudia|Reese, Alina|Budach, Wilfried|Sohn, Dennis|Janicke, Reiner U
PMID: 28348086
Journal: Oncol Lett. 2017 Feb;13(2):722-730.
Title: MicroRNA-93-5p increases multidrug resistance in human colorectal carcinoma cells by downregulating cyclin dependent kinase inhibitor 1A gene expression.
Author: Wang, Shi-Jun|Cao, Yun-Fei|Yang, Zu-Qing|Jiang, Zhi-Yuan|Cai, Bin|Guo, Jiao|Zhang, Sen|Zhang, Xiao-Long|Gao, Feng
PMID: 28356951
Journal: Oncogene. 2017 Jul 27;36(30):4336-4348.
Title: TGFbeta engages MEK/ERK to differentially regulate benign and malignant pancreas cell function.
Author: Principe, D R|Diaz, A M|Torres, C|Mangan, R J|DeCant, B|McKinney, R|Tsao, M-S|Lowy, A|Munshi, H G|Jung, B|Grippo, P J
PMID: 28368414
Journal: Am J Transl Res. 2017 Mar 15;9(3):1088-1100. eCollection 2017.
Title: Celecoxib enhances the radiosensitivity of HCT116 cells in a COX-2 independent manner by up-regulating BCCIP.
Author: Xu, Xiao-Ting|Hu, Wen-Tao|Zhou, Ju-Ying|Tu, Yu
PMID: 28386336
Journal: Oncotarget. 2017 Apr 11;8(15):25055-25065.
Title: Specific up-regulation of p21 by a small active RNA sequence suppresses human colorectal cancer growth.
Author: Wang, Lu-Lu|Guo, Hui-Hui|Zhan, Yun|Feng, Chen-Lin|Huang, Shuai|Han, Yan-Xing|Zheng, Wen-Sheng|Jiang, Jian-Dong
PMID: 28445988
Journal: Mar Drugs. 2017 May 30;15(6). pii: md15060154.
Title: Induction of p53-Independent Apoptosis and G1 Cell Cycle Arrest by Fucoidan in HCT116 Human Colorectal Carcinoma Cells.
Author: Park, Hye Young|Park, Shin-Hyung|Jeong, Jin-Woo|Yoon, Dahye|Han, Min Ho|Lee, Dae-Sung|Choi, Grace|Yim, Mi-Jin|Lee, Jeong Min|Kim, Do-Hyung|Kim, Gi-Young|Choi, Il-Whan|Kim, Suhkmann|Kim, Heui-Soo|Cha, Hee-Jae|Choi, Yung Hyun
PMID: 28555064
Journal: Clin Epigenetics. 2017 Jun 8;9:62.
Title: Histone deacetylase inhibitors potentiate photodynamic therapy in colon cancer cells marked by chromatin-mediated epigenetic regulation of CDKN1A.
Author: Halaburkova, Andrea|Jendzelovsky, Rastislav|Koval, Jan|Herceg, Zdenko|Fedorocko, Peter|Ghantous, Akram
PMID: 28603560
Journal: Oncol Rep. 2017 Aug;38(2):975-984.
Title: KLF4 inhibits colorectal cancer cell proliferation dependent on NDRG2 signaling.
Author: Ma, Yongzheng|Wu, Lin|Liu, Xuewu|Xu, Yuqiao|Shi, Wei|Liang, Ye|Yao, Libo|Zheng, Jianyong|Zhang, Jian
PMID: 28656310
Journal: Biomaterials. 2017 Oct;141:13-28.
Title: Tumor-selective lipopolyplex encapsulated small active RNA hampers colorectal cancer growth in vitro and in orthotopic murine.
Author: Wang, Lu-Lu|Feng, Chen-Lin|Zheng, Wen-Sheng|Huang, Shuai|Zhang, Wen-Xuan|Wu, Hong-Na|Zhan, Yun|Han, Yan-Xing|Wu, Song|Jiang, Jian-Dong
PMID: 28666099
Journal: Chem Biol Interact. 2017 Sep 25;275:162-170.
Title: Antitumor activity of beta-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways.
Author: Daaboul, Hamid E|Daher, Costantine F|Bodman-Smith, Kikki|Taleb, Robin I|Shebaby, Wassim N|Boulos, Joelle|Dagher, Carole|Mroueh, Mohamad A|El-Sibai, Mirvat
PMID: 28782499
Journal: Theranostics. 2017 Jun 11;7(8):2339-2349.
Title: YD277 Suppresses Triple-Negative Breast Cancer Partially Through Activating the Endoplasmic Reticulum Stress Pathway.
Author: Chen, Zekun|Wu, Qiuju|Ding, Ye|Zhou, Wenhui|Liu, Rong|Chen, Haiying|Zhou, Jia|Feng, Jing|Chen, Ceshi
PMID: 28740556
Journal: Exp Ther Med. 2017 Dec;14(6):5379-5386.
Title: Hyperthermia exposure induces apoptosis and inhibits proliferation in HCT116 cells by upregulating miR-34a and causing transcriptional activation of p53.
Author: Luo, Zan|Zheng, Kangxia|Fan, Qi|Jiang, Xinyao|Xiong, Dehai
PMID: 29285066
Journal: BMC Complement Altern Med. 2017 Dec 13;17(1):531.
Title: Antitumor effect of Quercetin on Y79 retinoblastoma cells via activation of JNK and p38 MAPK pathways.
Author: Liu, Haojie|Zhou, Ming
PMID: 29237430
Journal: Oncotarget. 2017 Aug 24;8(47):83207-83224.
Title: Inhibition of cell cycle progression by the hydroxytyrosol-cetuximab combination yields enhanced chemotherapeutic efficacy in colon cancer cells.
Author: Terzuoli, Erika|Nannelli, Ginevra|Frosini, Maria|Giachetti, Antonio|Ziche, Marina|Donnini, Sandra
PMID: 29137335
Journal: Oncotarget. 2017 Sep 15;8(47):82968-82980.
Title: RRS1 silencing suppresses colorectal cancer cell proliferation and tumorigenesis by inhibiting G2/M progression and angiogenesis.
Author: Wu, Xin-Lin|Yang, Zhi-Wen|He, Li|Dong, Pei-De|Hou, Ming-Xing|Meng, Xing-Kai|Zhao, Hai-Ping|Wang, Zhao-Yang|Wang, Feng|Baoluri|Wurenqimuge|Agudamu|Jia, Yong-Feng|Shi, Lin
PMID: 29137316
Journal: Sci Rep. 2017 Oct 23;7(1):13749.
Title: Regiospecific Synthesis of Ring A Fused Withaferin A Isoxazoline Analogues: Induction of Premature Senescence by W-2b in Proliferating Cancer Cells.
Author: Rasool, Faheem|Nayak, Debasis|Katoch, Archana|Faheem, Mir Mohd|Yousuf, Syed Khalid|Hussain, Nazar|Belawal, Chetan|Satti, N K|Goswami, Anindya|Mukherjee, Debaraj
PMID: 29062040
Journal: Oncol Rep. 2017 Dec;38(6):3685-3692.
Title: Downregulation of ZNF278 arrests the cell cycle and decreases the proliferation of colorectal cancer cells via inhibition of the ERK/MAPK pathway.
Author: Tian, Xiao-Qing|Guo, Fang-Fang|Sun, Dan-Feng|Wang, Ying-Chao|Yang, Li|Chen, Sheng-Liang|Hong, Jie|Fang, Jing-Yuan
PMID: 29039562
Journal: Oncotarget. 2017 Jul 22;8(40):68448-68459.
Title: Melanoma antigen A12 regulates cell cycle via tumor suppressor p21 expression.
Author: Yanagi, Teruki|Nagai, Ko|Shimizu, Hiroshi|Matsuzawa, Shu-Ichi
PMID: 28978129
Journal: Cell Oncol (Dordr). 2017 Dec;40(6):593-607.
Title: TRAIL enhances quinacrine-mediated apoptosis in breast cancer cells through induction of autophagy via modulation of p21 and DR5 interactions.
Author: Das, Sarita|Nayak, Anmada|Siddharth, Sumit|Nayak, Deepika|Narayan, Satya|Kundu, Chanakya Nath
PMID: 28936683
Journal: Oncotarget. 2017 Jun 7;8(32):53262-53275.
Title: Jagged-2 (JAG2) enhances tumorigenicity and chemoresistance of colorectal cancer cells.
Author: Vaish, Vivek|Kim, Joohwee|Shim, Minsub
PMID: 28881809
Journal: Food Funct. 2017 Oct 18;8(10):3553-3562.
Title: In vitro and in vivo inhibitory effects of a Pleurotus eryngii protein on colon cancer cells.
Author: Yuan, Biao|Ma, Ning|Zhao, Liyan|Zhao, Ermin|Gao, Zili|Wang, Weicang|Song, Mingyue|Zhang, Guodong|Hu, Qiuhui|Xiao, Hang
PMID: 28880032
Journal: Molecules. 2017 Aug 17;22(8). pii: molecules22081361.
Title: Anticancer Activity of Ramalin, a Secondary Metabolite from the Antarctic Lichen Ramalina terebrata, against Colorectal Cancer Cells.
Author: Suh, Sung-Suk|Kim, Tai Kyoung|Kim, Jung Eun|Hong, Ju-Mi|Nguyen, Trang Thu Thi|Han, Se Jong|Youn, Ui Joung|Yim, Joung Han|Kim, Il-Chan
PMID: 28817102
Journal: Cell Death Dis. 2017 Aug 10;8(8):e2997.
Title: Long noncoding RNA CRNDE promotes colorectal cancer cell proliferation via epigenetically silencing DUSP5/CDKN1A expression.
Author: Ding, Jie|Li, Juan|Wang, HaiYan|Tian, Yun|Xie, Min|He, XueZhi|Ji, Hao|Ma, Zhonghua|Hui, Bingqing|Wang, Keming|Ji, Guozhong
PMID: 28796262
Journal: Sci Rep. 2017 Aug 8;7(1):7599.
Title: Anti-colon cancer effect of caffeic acid p-nitro-phenethyl ester in vitro and in vivo and detection of its metabolites.
Author: Tang, Hao|Yao, Xiaofang|Yao, Cong|Zhao, Xiaoyan|Zuo, Hua|Li, Zhubo
PMID: 28790461
Journal: Oncol Lett. 2017 Aug;14(2):2223-2231.
Title: p53 performs an essential role in mediating the oncogenic stimulus triggered by loss of expression of neurofibromatosis type 2 during in vitro tumor progression.
Author: Li, Xiye|Chen, Hongsai|Xue, Lu|Pang, Xiuhong|Zhang, Xiaoman|Zhu, Zhengjie|Zhu, Weidong|Wang, Zhaoyan|Wu, Hao
PMID: 28789444
Journal: Mol Biosyst. 2017 Oct 24;13(11):2195-2201.
Title: PANDAR: a pivotal cancer-related long non-coding RNA in human cancers.
Author: Li, Jinglin|Li, Zhenglong|Zheng, Wangyang|Li, Xinheng|Wang, Zhidong|Cui, Yunfu|Jiang, Xingming
PMID: 28976505
Journal: Oncotarget. 2018 Jun 1;9(42):26817-26833.
Title: Nucleolin facilitates nuclear retention of an ultraconserved region containing TRA2beta4 and accelerates colon cancer cell growth.
Author: Satake, Yuzuru|Kuwano, Yuki|Nishikawa, Tatsuya|Fujita, Kinuyo|Saijo, Saki|Itai, Miki|Tanaka, Hiroki|Nishida, Kensei|Rokutan, Kazuhito
PMID: 29928487
Journal: FEBS J. 2018 Jun 22.
Title: BCCIP binds to and activates its promoter in a YY1-dependent fashion in HCT116 cells.
Author: Sui, Yi|Li, Fuqiang|Wu, Tingting|Ding, Jian|Lu, Zeming|Wang, Lingyao|Yang, Yang|Wang, Fei|Zhao, Linhong|Zhu, Huihui|Wei, Tao|Jin, Jingji|Cai, Yong
PMID: 29932276
Journal: Oncol Lett. 2018 Jul;16(1):1291-1297.
Title: Liver kinase B1/adenosine monophosphate-activated protein kinase signaling axis induces p21/WAF1 expression in a p53-dependent manner.
Author: Ma, Qing|Xiao, Ping|Sun, Linlin|Wang, Jing|Zhong, Diansheng
PMID: 29963200
Journal: Int J Med Sci. 2018 Jun 12;15(9):929-936.
Title: Anti-inflammation and Anti-Cancer Activity of Ethanol Extract of Antarctic Freshwater Microalga, Micractinium sp.
Author: Suh, Sung-Suk|Hong, Ju-Mi|Kim, Eun Jae|Jung, Seung Won|Kim, Sun-Mi|Kim, Jung Eun|Kim, Il-Chan|Kim, Sanghee
PMID: 30008606
Journal: Cell Prolif. 2018 Aug 24:e12505.
Title: Upregulated miR-1258 regulates cell cycle and inhibits cell proliferation by directly targeting E2F8 in CRC.
Author: Zhang, Zhiyuan|Li, Jie|Huang, Yuanjian|Peng, Wen|Qian, Wenwei|Gu, Jiou|Wang, Qingyuan|Hu, Tao|Ji, Dongjian|Ji, Bing|Zhang, Yue|Wang, Shijia|Sun, Yueming
PMID: 30144184
Journal: Onco Targets Ther. 2018 Aug 14;11:4877-4891.
Title: Prognostic value of long noncoding RNAs in gastric cancer: a meta-analysis.
Author: Gao, Song|Zhao, Zhi-Ying|Wu, Rong|Zhang, Yue|Zhang, Zhen-Yong
PMID: 30147339
Journal: PLoS One. 2018 Sep 6;13(9):e0202903.
Title: Novel isothiacalothrixin B analogues exhibit cytotoxic activity on human colon cancer cells in vitro by inducing irreversible DNA damage.
Author: Dhatchana Moorthy, Nachiappan|Muthu Ramalingam, Bose|Iqbal, Saleem|Mohanakrishnan, Arasambattu K|Gunasekaran, Krishnasamy|Vellaichamy, Elangovan
PMID: 30188913
Journal: J Cell Physiol. 2018 Sep 7.
Title: The prognostic and therapeutic values of long noncoding RNA PANDAR in colorectal cancer.
Author: Rivandi, Mahdi|Pasdar, Alireza|Hamzezadeh, Leila|Tajbakhsh, Amir|Seifi, Sima|Moetamani-Ahmadi, Mehrdad|Ferns, Gordon A|Avan, Amir
PMID: 30191971
Journal: Oncol Lett. 2018 Oct;16(4):5275-5281.
Title: Increased EZH2 expression during the adenoma-carcinoma sequence in colorectal cancer.
Author: Ohuchi, Mayuko|Sakamoto, Yasuo|Tokunaga, Ryuma|Kiyozumi, Yuki|Nakamura, Kenichi|Izumi, Daisuke|Kosumi, Keisuke|Harada, Kazuto|Kurashige, Junji|Iwatsuki, Masaaki|Baba, Yoshifumi|Miyamoto, Yuji|Yoshida, Naoya|Shono, Takashi|Naoe, Hideaki|Sasaki, Yutaka|Baba
PMID: 30214616
Journal: Oncotarget. 2018 Aug 28;9(67):32822-32840.
Title: Vitamin C promotes decitabine or azacytidine induced DNA hydroxymethylation and subsequent reactivation of the epigenetically silenced tumour suppressor CDKN1A in colon cancer cells.
Author: Gerecke, Christian|Schumacher, Fabian|Edlich, Alexander|Wetzel, Alexandra|Yealland, Guy|Neubert, Lena Katharina|Scholtka, Bettina|Homann, Thomas|Kleuser, Burkhard
PMID: 30214687
Journal: J Gastroenterol Hepatol. 2018 Sep 18.
Title: RASSF1A suppresses colorectal tumor cell growth through p53-dependent p21(WAF1) activation.
Author: Oh, Shin Ju|Lee, Min-Goo|Moon, Jung Rock|Lee, Chang Kyun|Chi, Sung-Gil|Kim, Hyo Jong
PMID: 30226276
Journal: Int J Mol Med. 2018 Sep 25.
Title: Expression levels of hnRNP K and p21WAF1/CIP1 are associated with resistance to radiochemotherapy independent of p53 pathway activation in rectal adenocarcinoma.
Author: Daskalaki, Wassiliki|Wardelmann, Eva|Port, Matthias|Stock, Katharina|Steinestel, Julie|Huss, Sebastian|Sperveslage, Jan|Steinestel, Konrad|Eder, Stefan
PMID: 30272263
Journal: Eur J Pharmacol. 2018 Oct 12;841:1-9.
Title: A new chalcone derivative, 3-phenyl-1-(2,4,6-tris(methoxymethoxy)phenyl)prop-2-yn-1-one), inhibits phorbol ester-induced metastatic activity of colorectal cancer cells through upregulation of heme oxygenase-1.
Author: Jin, Hao|Kim, Hak Sung|Seo, Geom Seog|Lee, Sung Hee
PMID: 30321531
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2018 May 20;38(5):511-519.
Title: [Role of allograft inflammatory factor-1 in regulating the proliferation, migration and apoptosis of colorectal cancer cells].
Author: Ai, Xiao-Lan|Yao, Fang|Wang, Xiao-Jing|Duan, Dong-Bei|Li, Ke|Hu, Zi-You|Yin, Guo|Wang, Mei|Wu, Bing-Yi
PMID: 29891445
Journal: Curr Mol Med. 2018;18(1):25-35.
Title: LOH12CR1 is a Novel Tumor Suppressor Inhibiting Tumor Growth Through Deregulation of G1/S Checkpoint in Human Colorectal Carcinoma.
Author: Huang, H|Shen, H|Wang, Y|Wang, X|Chen, Q|Wang, Y|Yan, H|Liu, Z|Shi, X
PMID: 29879888
Journal: Cancer Sci. 2018 Aug;109(8):2458-2468.
Title: HNRNPLL stabilizes mRNA for DNA replication proteins and promotes cell cycle progression in colorectal cancer cells.
Author: Sakuma, Keiichiro|Sasaki, Eiichi|Kimura, Kenya|Komori, Koji|Shimizu, Yasuhiro|Yatabe, Yasushi|Aoki, Masahiro
PMID: 29869816
Journal: Int J Mol Sci. 2018 May 31;19(6). pii: ijms19061625.
Title: NSC 95397 Suppresses Proliferation and Induces Apoptosis in Colon Cancer Cells through MKP-1 and the ERK1/2 Pathway.
Author: Dubey, Navneet Kumar|Peng, Bou-Yue|Lin, Chien-Min|Wang, Peter D|Wang, Joseph R|Chan, Chun-Hao|Wei, Hong-Jian|Deng, Win-Ping
PMID: 29857489
Journal: Apoptosis. 2018 May 12. pii: 10.1007/s10495-018-1457-8.
Title: Resveratrol analogue, (E)-N-(2-(4-methoxystyryl) phenyl) furan-2-carboxamide induces G2/M cell cycle arrest through the activation of p53-p21(CIP1/WAF1) in human colorectal HCT116 cells.
Author: Cheah, Foo Kit|Leong, Kok Hoong|Thomas, Noel Francis|Chin, Hui Kee|Ariffin, Azhar|Awang, Khalijah
PMID: 29754265
Journal: Mol Carcinog. 2018 Aug;57(8):1055-1066.
Title: Phenylbutyl isoselenocyanate induces reactive oxygen species to inhibit androgen receptor and to initiate p53-mediated apoptosis in LNCaP prostate cancer cells.
Author: Wu, Wei|Karelia, Deepkamal|Pramanik, Kartick|Amin, Shantu G|Sharma, Arun K|Jiang, Cheng|Lu, Junxuan
PMID: 29668110
Journal: Medchemcomm. 2018;9(1):87-99.
Title: Phenylethynyl-substituted Heterocycles Inhibit Cyclin D1 and Induce the Expression of Cyclin-dependent Kinase Inhibitor p21(Wif1/Cip1) in Colorectal Cancer Cells.
Author: Sviripa, Vitaliy M|Kril, Liliia M|Zhang, Wen|Xie, Yanqi|Wyrebek, Przemyslaw|Ponomareva, Larissa|Liu, Xifu|Yuan, Yaxia|Zhan, Chang-Guo|Watt, David S|Liu, Chunming
PMID: 29527286
Journal: Oncol Rep. 2018 May;39(5):2297-2305.
Title: Delineating the underlying molecular mechanisms and key genes involved in metastasis of colorectal cancer via bioinformatics analysis.
Author: Qi, Chao|Chen, Yuanlei|Zhou, Yixuan|Huang, Xucheng|Li, Guoli|Zeng, Jin|Ruan, Zhi|Xie, Xinyou|Zhang, Jun
PMID: 29517105
Journal: Oncotarget. 2017 Dec 27;9(10):9010-9020.
Title: The prognostic significance of protein arginine methyltransferase 6 expression in colon cancer.
Author: Lim, Yongchul|Yu, Suyeun|Yun, Jung-A|Do, In-Gu|Cho, Lan|Kim, Yang Hee|Kim, Hee Cheol
PMID: 29507670
Journal: Anticancer Agents Med Chem. 2018;18(4):565-572.
Title: Riluzole Inhibits Proliferation, Migration and Cell Cycle Progression and Induces Apoptosis in Tumor Cells of Various Origins.
Author: Lemieszek, Marta Kinga|Stepulak, Andrzej|Sawa-Wejksza, Katarzyna|Czerwonka, Arkadiusz|Ikonomidou, Chrysanthy|Rzeski, Wojciech
PMID: 29493465
Journal: Sci Rep. 2018 Feb 9;8(1):2742.
Title: ZFP36L1 and ZFP36L2 inhibit cell proliferation in a cyclin D-dependent and p53-independent manner.
Author: Suk, Fat-Moon|Chang, Chi-Ching|Lin, Ren-Jye|Lin, Shyr-Yi|Liu, Shih-Chen|Jau, Chia-Feng|Liang, Yu-Chih
PMID: 29426877
Journal: Cancer Lett. 2018 Apr 10;419:116-127.
Title: Sorting nexin 10 acts as a tumor suppressor in tumorigenesis and progression of colorectal cancer through regulating chaperone mediated autophagy degradation of p21(Cip1/WAF1).
Author: Zhang, Sulin|Hu, Bin|You, Yan|Yang, Zhiwen|Liu, Lixin|Tang, Huanhuan|Bao, Weilian|Guan, Yunyun|Shen, Xiaoyan
PMID: 29355659
Journal: PLoS One. 2018 Jan 17;13(1):e0189582.
Title: Prediction of novel target genes and pathways involved in bevacizumab-resistant colorectal cancer.
Author: Makondi, Precious Takondwa|Lee, Chia-Hwa|Huang, Chien-Yu|Chu, Chi-Ming|Chang, Yu-Jia|Wei, Po-Li
PMID: 29342159
Journal: Breast Cancer. 2018 Mar;25(2):224-232.
Title: UBAP2L silencing inhibits cell proliferation and G2/M phase transition in breast cancer.
Author: He, Jing|Chen, Yuanping|Cai, Lu|Li, Zelei|Guo, Xiaoqing
PMID: 29196913