Primary Site >> Liver Cancer
Gene >> CDK9
| 1. | |||||||||||
| Journal: | J Pharmacobiodyn. 1988 Jul;11(7):472-8. | ||||||||||
| Title: | Local induction of a tumor necrosis factor (TNF)-like cytotoxic factor in murine tissues with tumorous and nontumorous inflammation after systemic administration of antitumor polysaccharides. | ||||||||||
| Author: | Takahashi, K|Yamazaki, M|Abe, S | ||||||||||
| PMID: | 3183925 | ||||||||||
| 2. | |||||||||||
| Journal: | Cancer Lett. 2010 Jan 28;287(2):196-206. | ||||||||||
| Title: | Xylocydine, a novel Cdk inhibitor, is an effective inducer of apoptosis in hepatocellular carcinoma cells in vitro and in vivo. | ||||||||||
| Author: | Cho, Seung-Ju|Lee, Seung-Soo|Kim, Young-Jong|Park, Byoung-Duck|Choi, Joon-Seok|Liu, Linhua|Ham, Young-Mi|Moon Kim, B|Lee, Seung-Ki | ||||||||||
| PMID: | 19616371 | ||||||||||
| 3. | |||||||||||
| Journal: | J Biol Chem. 2011 Jun 3;286(22):19662-71. | ||||||||||
| Title: | Ibulocydine is a novel prodrug Cdk inhibitor that effectively induces apoptosis in hepatocellular carcinoma cells. | ||||||||||
| Author: | Cho, Seung-Ju|Kim, Young-Jong|Surh, Young-Joon|Kim, B Moon|Lee, Seung-Ki | ||||||||||
| PMID: | 21478145 | ||||||||||
| 4. | |||||||||||
| Journal: | Mol Cancer Ther. 2013 Oct;12(10):1947-57. | ||||||||||
| Title: | Novel inhibitors of cyclin-dependent kinases combat hepatocellular carcinoma without inducing chemoresistance. | ||||||||||
| Author: | Haider, Christine|Grubinger, Markus|Reznickova, Eva|Weiss, Thomas S|Rotheneder, Hans|Miklos, Walter|Berger, Walter|Jorda, Radek|Zatloukal, Marek|Gucky, Tomas|Strnad, Miroslav|Krystof, Vladimir|Mikulits, Wolfgang | ||||||||||
| PMID: | 23939380 | ||||||||||
| 5. | |||||||||||
| Journal: | Genes Dev. 2014 Aug 15;28(16):1800-14. | ||||||||||
| Title: | CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma. | ||||||||||
| Author: | Huang, Chun-Hao|Lujambio, Amaia|Zuber, Johannes|Tschaharganeh, Darjus F|Doran, Michael G|Evans, Michael J|Kitzing, Thomas|Zhu, Nan|de Stanchina, Elisa|Sawyers, Charles L|Armstrong, Scott A|Lewis, Jason S|Sherr, Charles J|Lowe, Scott W | ||||||||||
| PMID: | 25128497 | ||||||||||
| 6. | |||||||||||
| Journal: | Chem Biol Interact. 2015 Dec 5;242:107-22. | ||||||||||
| Title: | Novel carbocyclic curcumin analog CUR3d modulates genes involved in multiple apoptosis pathways in human hepatocellular carcinoma cells. | ||||||||||
| Author: | Bhullar, Khushwant S|Jha, Amitabh|Rupasinghe, H P Vasantha | ||||||||||
| PMID: | 26409325 | ||||||||||
| 7. | |||||||||||
| Journal: | Int J Biochem Cell Biol. 2017 Feb;83:47-55. | ||||||||||
| Title: | Ibulocydine sensitizes human hepatocellular carcinoma cells to TRAIL-induced apoptosis via calpain-mediated Bax cleavage. | ||||||||||
| Author: | Park, Seok Soon|Jwa, Eunjin|Shin, Seol Hwa|Ju, Eun Jin|Park, Intae|Pak, Jhang Ho|Hwang, Jung Jin|Cho, Dong-Hyung|Kim, B Moon|Kim, Sung-Bae|Lee, Jung Shin|Song, Si Yeol|Jeong, Seong-Yun|Choi, Eun Kyung | ||||||||||
| PMID: | 27923747 | ||||||||||
| 8. | |||||||||||
| Journal: | Eur J Med Chem. 2018 Sep 13;158:896-916. | ||||||||||
| Title: | Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino)cyclohexyl)amino)pyridin-4- yl)thiazol-2-yl)amino)methyl)tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor. | ||||||||||
| Author: | Wang, Beilei|Wu, Jiaxin|Wu, Yun|Chen, Cheng|Zou, Fengming|Wang, Aoli|Wu, Hong|Hu, Zhenquan|Jiang, Zongru|Liu, Qingwang|Wang, Wei|Zhang, Yicong|Liu, Feiyang|Zhao, Ming|Hu, Jie|Huang, Tao|Ge, Juan|Wang, Li|Ren, Tao|Wang, Yuxin|Liu, Jing|Liu, Qingsong | ||||||||||
| PMID: | 30253346 | ||||||||||