Primary Site >> Liver Cancer
Gene >> CDK9
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Ref: Local induction of a tumor necrosis factor (TNF)-like cytotoxic factor in murine tissues with tumorous and nontumorous inflammation after systemic administration of antitumor polysaccharides. PMID: 3183925 |
Ref: Xylocydine, a novel Cdk inhibitor, is an effective inducer of apoptosis in hepatocellular carcinoma cells in vitro and in vivo. PMID: 19616371 |
Ref: Ibulocydine is a novel prodrug Cdk inhibitor that effectively induces apoptosis in hepatocellular carcinoma cells. PMID: 21478145 |
Ref: Novel inhibitors of cyclin-dependent kinases combat hepatocellular carcinoma without inducing chemoresistance. PMID: 23939380 |
Ref: CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma. PMID: 25128497 |
Ref: Novel carbocyclic curcumin analog CUR3d modulates genes involved in multiple apoptosis pathways in human hepatocellular carcinoma cells. PMID: 26409325 |
Ref: Ibulocydine sensitizes human hepatocellular carcinoma cells to TRAIL-induced apoptosis via calpain-mediated Bax cleavage. PMID: 27923747 |
Ref: Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino)cyclohexyl)amino)pyridin-4- yl)thiazol-2-yl)amino)methyl)tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor. PMID: 30253346 |