Primary Site >> Colorectal Cancer

Gene >> CDK7

Journal: Pflugers Arch. 1993 Mar;422(6):539-45.
Title: Regulation of chloride channels in the human colon carcinoma cell line HT29.cl19A.
Author: Kansen, M|Bajnath, R B|Groot, J A|de Jonge, H R|Scholte, B|Hoogeveen, A T|Bijman, J
PMID: 8385768
Journal: Oncogene. 1994 Jul;9(7):1977-88.
Title: Two novel human serine/threonine kinases with homologies to the cell cycle regulating Xenopus MO15, and NIMA kinases: cloning and characterization of their expression pattern.
Author: Levedakou, E N|He, M|Baptist, E W|Craven, R J|Cance, W G|Welcsh, P L|Simmons, A|Naylor, S L|Leach, R J|Lewis, T B
PMID: 8208544
Journal: Oncogene. 1999 Oct 14;18(42):5765-72.
Title: RNA synthesis block by 5, 6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) triggers p53-dependent apoptosis in human colon carcinoma cells.
Author: te Poele, R H|Okorokov, A L|Joel, S P
PMID: 10523857
Journal: Cancer Res. 2002 May 15;62(10):2923-8.
Title: Development of a highly specialized cDNA array for the study and diagnosis of epithelial ovarian cancer.
Author: Sawiris, G Peter|Sherman-Baust, Cheryl A|Becker, Kevin G|Cheadle, Chris|Teichberg, Diane|Morin, Patrice J
PMID: 12019173
Journal: Biochem Pharmacol. 2003 Apr 1;65(7):1053-60.
Title: Resveratrol-induced G2 arrest through the inhibition of CDK7 and p34CDC2 kinases in colon carcinoma HT29 cells.
Author: Liang, Yu-Chih|Tsai, Shu-Huei|Chen, Linda|Lin-Shiau, Shoei-Yn|Lin, Jen-Kun
PMID: 12663041
Journal: Cancer Res. 2004 Jan 1;64(1):262-72.
Title: The Cyclin-dependent kinase inhibitor CYC202 (R-roscovitine) inhibits retinoblastoma protein phosphorylation, causes loss of Cyclin D1, and activates the mitogen-activated protein kinase pathway.
Author: Whittaker, Steven R|Walton, Mike I|Garrett, Michelle D|Workman, Paul
PMID: 14729633
Journal: Cancer Prev Res (Phila). 2009 Sep;2(9):800-6.
Title: Chemoprevention of mouse intestinal tumorigenesis by the cyclin-dependent kinase inhibitor SNS-032.
Author: Boquoi, Amelie|Chen, Tina|Enders, Greg H
PMID: 19723896
Journal: Eur J Cancer. 2010 Jun;46(9):1752-61.
Title: Functional characterisation of cell cycle-related kinase (CCRK) in colorectal cancer carcinogenesis.
Author: An, Xiaomeng|Ng, Samuel S|Xie, Dan|Zeng, Yi-Xin|Sze, Johnny|Wang, Jide|Chen, Yang Chao|Chow, Billy K C|Lu, Gang|Poon, Wai Sang|Kung, Hsiang-Fu|Wong, Benjamin C Y|Lin, Marie Chia-Mi
PMID: 20466538
Journal: Bioorg Med Chem. 2011 Nov 15;19(22):6949-65.
Title: Design, synthesis and biological evaluation of 6-pyridylmethylaminopurines as CDK inhibitors.
Author: Wilson, Stuart C|Atrash, Butrus|Barlow, Clare|Eccles, Susan|Fischer, Peter M|Hayes, Angela|Kelland, Lloyd|Jackson, Wayne|Jarman, Michael|Mirza, Amin|Moreno, Javier|Nutley, Bernard P|Raynaud, Florence I|Sheldrake, Peter|Walton, Mike|Westwood, Robert|Whitta
PMID: 21982796
Journal: Cancer Cell Int. 2015 Apr 24;15:46.
Title: Growth inhibitory and chemo-sensitization effects of naringenin, a natural flavanone purified from Thymus vulgaris, on human breast and colorectal cancer.
Author: Abaza, Mohamed Salah I|Orabi, Khaled Y|Al-Quattan, Ebtehal|Al-Attiyah, Raja'a J
PMID: 26074733
Journal: Front Pharmacol. 2017 Feb 2;8:38.
Title: Pharmacogenomic Characterization and Isobologram Analysis of the Combination of Ascorbic Acid and Curcumin-Two Main Metabolites of Curcuma longa-in Cancer Cells.
Author: Ooko, Edna|Kadioglu, Onat|Greten, Henry J|Efferth, Thomas
PMID: 28210221
Journal: Cell Rep. 2017 Oct 10;21(2):467-481.
Title: Activation of the p53 Transcriptional Program Sensitizes Cancer Cells to Cdk7 Inhibitors.
Author: Kalan, Sampada|Amat, Ramon|Schachter, Miriam Merzel|Kwiatkowski, Nicholas|Abraham, Brian J|Liang, Yanke|Zhang, Tinghu|Olson, Calla M|Larochelle, Stephane|Young, Richard A|Gray, Nathanael S|Fisher, Robert P
PMID: 29020632
Journal: Mol Cancer Ther. 2018 Jun;17(6):1156-1166.
Title: ICEC0942, an Orally Bioavailable Selective Inhibitor of CDK7 for Cancer Treatment.
Author: Patel, Hetal|Periyasamy, Manikandan|Sava, Georgina P|Bondke, Alexander|Slafer, Brian W|Kroll, Sebastian H B|Barbazanges, Marion|Starkey, Richard|Ottaviani, Silvia|Harrod, Alison|Aboagye, Eric O|Buluwela, Laki|Fuchter, Matthew J|Barrett, Anthony G M|Coombe
PMID: 29545334