Primary Site >> Colorectal Cancer
Gene >> CDK7
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Ref: Regulation of chloride channels in the human colon carcinoma cell line HT29.cl19A. PMID: 8385768 |
Ref: Two novel human serine/threonine kinases with homologies to the cell cycle regulating Xenopus MO15, and NIMA kinases: cloning and characterization of their expression pattern. PMID: 8208544 |
Ref: RNA synthesis block by 5, 6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) triggers p53-dependent apoptosis in human colon carcinoma cells. PMID: 10523857 |
Ref: Development of a highly specialized cDNA array for the study and diagnosis of epithelial ovarian cancer. PMID: 12019173 |
Ref: Resveratrol-induced G2 arrest through the inhibition of CDK7 and p34CDC2 kinases in colon carcinoma HT29 cells. PMID: 12663041 |
Ref: The Cyclin-dependent kinase inhibitor CYC202 (R-roscovitine) inhibits retinoblastoma protein phosphorylation, causes loss of Cyclin D1, and activates the mitogen-activated protein kinase pathway. PMID: 14729633 |
Ref: Chemoprevention of mouse intestinal tumorigenesis by the cyclin-dependent kinase inhibitor SNS-032. PMID: 19723896 |
Ref: Functional characterisation of cell cycle-related kinase (CCRK) in colorectal cancer carcinogenesis. PMID: 20466538 |
Ref: Design, synthesis and biological evaluation of 6-pyridylmethylaminopurines as CDK inhibitors. PMID: 21982796 |
Ref: Growth inhibitory and chemo-sensitization effects of naringenin, a natural flavanone purified from Thymus vulgaris, on human breast and colorectal cancer. PMID: 26074733 |
Ref: Pharmacogenomic Characterization and Isobologram Analysis of the Combination of Ascorbic Acid and Curcumin-Two Main Metabolites of Curcuma longa-in Cancer Cells. PMID: 28210221 Ref: Activation of the p53 Transcriptional Program Sensitizes Cancer Cells to Cdk7 Inhibitors. PMID: 29020632 |
Ref: ICEC0942, an Orally Bioavailable Selective Inhibitor of CDK7 for Cancer Treatment. PMID: 29545334 |