Primary Site >> Colorectal Cancer

Gene >> CDK5

Journal: Cancer Biol Ther. 2005 Nov;4(11):1211-5. Epub 2005 Nov 8.
Title: Aberrant splicing of cables gene, a CDK regulator, in human cancers.
Author: Zhang, Hui|Duan, Hai Ou|Kirley, Sandra D|Zukerberg, Lawrence R|Wu, Chin-Lee
PMID: 16177568
Journal: Int J Oncol. 2006 Jan;28(1):191-4.
Title: CDK5 is a novel regulatory protein in PPARgamma ligand-induced antiproliferation.
Author: Kim, Eugene|Chen, Fei|Wang, Chia-Chi|Harrison, Lawrence E
PMID: 16327995
Journal: Mol Cancer Ther. 2009 Jan;8(1):194-202.
Title: Pharmacogenomic approach for the identification of novel determinants of acquired resistance to oxaliplatin in colorectal cancer.
Author: Martinez-Cardus, Anna|Martinez-Balibrea, Eva|Bandres, Eva|Malumbres, Raquel|Gines, Alba|Manzano, Jose Luis|Taron, Miquel|Garcia-Foncillas, Jesus|Abad, Albert
PMID: 19139129
Journal: Bioorg Med Chem Lett. 2012 Nov 15;22(22):6947-51.
Title: Design, synthesis and anticancer activity of 1-acyl-3-amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole derivatives.
Author: Bai, Xiao-Guang|Yu, Dong-Ke|Wang, Ju-Xian|Zhang, Hao|He, Hong-Wei|Shao, Rong-Guang|Li, Xue-Mei|Wang, Yu-Cheng
PMID: 23036956
Journal: Chem Biol Drug Des. 2015 Dec;86(6):1528-40.
Title: Characterization of a Pyrazolo[4,3-d]pyrimidine Inhibitor of Cyclin-Dependent Kinases 2 and 5 and Aurora A With Pro-Apoptotic and Anti-Angiogenic Activity In Vitro.
Author: Reznickova, Eva|Weitensteiner, Sabine|Havlicek, Libor|Jorda, Radek|Gucky, Tomas|Berka, Karel|Bazgier, Vaclav|Zahler, Stefan|Krystof, Vladimir|Strnad, Miroslav
PMID: 26198005
Journal: Cell Death Dis. 2016 Oct 13;7(10):e2415.
Title: CDK5 functions as a tumor promoter in human colorectal cancer via modulating the ERK5-AP-1 axis.
Author: Zhuang, Kangmin|Zhang, Juchang|Xiong, Man|Wang, Xianfei|Luo, Xiaobei|Han, Lu|Meng, Yan|Zhang, Yali|Liao, Wenting|Liu, Side
PMID: 27735944
Journal: Bioorg Med Chem Lett. 2017 Sep 15;27(18):4399-4404.
Title: Synthesis and biological evaluation of N9-cis-cyclobutylpurine derivatives for use as cyclin-dependent kinase (CDK) inhibitors.
Author: Park, Sun Jun|Kim, Eunjin|Yoo, Miyoun|Lee, Joo-Youn|Park, Chi Hoon|Hwang, Jong Yeon|Ha, Jae Du
PMID: 28827110
Journal: Oncotarget. 2017 Dec 28;9(4):5216-5232.
Title: Characterization of CDK(5) inhibitor, 20-223 (aka CP668863) for colorectal cancer therapy.
Author: Robb, Caroline M|Kour, Smit|Contreras, Jacob I|Agarwal, Ekta|Barger, Carter J|Rana, Sandeep|Sonawane, Yogesh|Neilsen, Beth K|Taylor, Margaret|Kizhake, Smitha|Thakare, Rhishikesh N|Chowdhury, Sanjib|Wang, Jing|Black, Jennifer D|Hollingsworth, Michael A|Bra
PMID: 29435174
Journal: Mol Cancer Ther. 2018 Jun;17(6):1156-1166.
Title: ICEC0942, an Orally Bioavailable Selective Inhibitor of CDK7 for Cancer Treatment.
Author: Patel, Hetal|Periyasamy, Manikandan|Sava, Georgina P|Bondke, Alexander|Slafer, Brian W|Kroll, Sebastian H B|Barbazanges, Marion|Starkey, Richard|Ottaviani, Silvia|Harrod, Alison|Aboagye, Eric O|Buluwela, Laki|Fuchter, Matthew J|Barrett, Anthony G M|Coombe
PMID: 29545334