Primary Site >> Colorectal Cancer
Gene >> CDK5
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Ref: Aberrant splicing of cables gene, a CDK regulator, in human cancers. PMID: 16177568 |
Ref: CDK5 is a novel regulatory protein in PPARgamma ligand-induced antiproliferation. PMID: 16327995 |
Ref: Pharmacogenomic approach for the identification of novel determinants of acquired resistance to oxaliplatin in colorectal cancer. PMID: 19139129 |
Ref: Design, synthesis and anticancer activity of 1-acyl-3-amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole derivatives. PMID: 23036956 |
Ref: Characterization of a Pyrazolo[4,3-d]pyrimidine Inhibitor of Cyclin-Dependent Kinases 2 and 5 and Aurora A With Pro-Apoptotic and Anti-Angiogenic Activity In Vitro. PMID: 26198005 |
Ref: CDK5 functions as a tumor promoter in human colorectal cancer via modulating the ERK5-AP-1 axis. PMID: 27735944 |
Ref: Synthesis and biological evaluation of N9-cis-cyclobutylpurine derivatives for use as cyclin-dependent kinase (CDK) inhibitors. PMID: 28827110 |
Ref: Characterization of CDK(5) inhibitor, 20-223 (aka CP668863) for colorectal cancer therapy. PMID: 29435174 Ref: ICEC0942, an Orally Bioavailable Selective Inhibitor of CDK7 for Cancer Treatment. PMID: 29545334 |