Primary Site >> Colorectal Cancer
Gene >> CDK19
| 1. | |||||||||||
| Journal: | Mol Carcinog. 2013 Jun;52(6):459-74. | ||||||||||
| Title: | Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. | ||||||||||
| Author: | Humphreys, Karen J|Cobiac, Lynne|Le Leu, Richard K|Van der Hoek, Mark B|Michael, Michael Z | ||||||||||
| PMID: | 22308110 | ||||||||||
| 2. | |||||||||||
| Journal: | J Med Chem. 2016 Feb 11;59(3):1078-101. | ||||||||||
| Title: | Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19. | ||||||||||
| Author: | Mallinger, Aurelie|Schiemann, Kai|Rink, Christian|Stieber, Frank|Calderini, Michel|Crumpler, Simon|Stubbs, Mark|Adeniji-Popoola, Olajumoke|Poeschke, Oliver|Busch, Michael|Czodrowski, Paul|Musil, Djordje|Schwarz, Daniel|Ortiz-Ruiz, Maria-Jesus|Schneider, R | ||||||||||
| PMID: | 26796641 | ||||||||||
| 3. | |||||||||||
| Journal: | Bioorg Med Chem Lett. 2016 Mar 1;26(5):1443-51. | ||||||||||
| Title: | Discovery of potent and selective CDK8 inhibitors from an HSP90 pharmacophore. | ||||||||||
| Author: | Schiemann, Kai|Mallinger, Aurelie|Wienke, Dirk|Esdar, Christina|Poeschke, Oliver|Busch, Michael|Rohdich, Felix|Eccles, Suzanne A|Schneider, Richard|Raynaud, Florence I|Czodrowski, Paul|Musil, Djordje|Schwarz, Daniel|Urbahns, Klaus|Blagg, Julian | ||||||||||
| PMID: | 26852363 | ||||||||||
| 4. | |||||||||||
| Journal: | Front Pharmacol. 2017 Feb 2;8:38. | ||||||||||
| Title: | Pharmacogenomic Characterization and Isobologram Analysis of the Combination of Ascorbic Acid and Curcumin-Two Main Metabolites of Curcuma longa-in Cancer Cells. | ||||||||||
| Author: | Ooko, Edna|Kadioglu, Onat|Greten, Henry J|Efferth, Thomas | ||||||||||
| PMID: | 28210221 | ||||||||||
| 5. | |||||||||||
| Journal: | Cell Rep. 2017 Nov 7;21(6):1495-1506. | ||||||||||
| Title: | CDK8 Kinase Activity Promotes Glycolysis. | ||||||||||
| Author: | Galbraith, Matthew D|Andrysik, Zdenek|Pandey, Ahwan|Hoh, Maria|Bonner, Elizabeth A|Hill, Amanda A|Sullivan, Kelly D|Espinosa, Joaquin M | ||||||||||
| PMID: | 29117556 | ||||||||||
| 6. | |||||||||||
| Journal: | J Biol Chem. 2018 Mar 30;293(13):4870-4882. | ||||||||||
| Title: | Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19. | ||||||||||
| Author: | Park, Min Ju|Shen, Hailian|Spaeth, Jason M|Tolvanen, Jaana H|Failor, Courtney|Knudtson, Jennifer F|McLaughlin, Jessica|Halder, Sunil K|Yang, Qiwei|Bulun, Serdar E|Al-Hendy, Ayman|Schenken, Robert S|Aaltonen, Lauri A|Boyer, Thomas G | ||||||||||
| PMID: | 29440396 | ||||||||||
| 7. | |||||||||||
| Journal: | Mol Cell Biol. 2018 May 15;38(11). pii: MCB.00573-17. | ||||||||||
| Title: | Depletion of Mediator Kinase Module Subunits Represses Superenhancer-Associated Genes in Colon Cancer Cells. | ||||||||||
| Author: | Kuuluvainen, Emilia|Domenech-Moreno, Eva|Niemela, Elina H|Makela, Tomi P | ||||||||||
| PMID: | 29507187 | ||||||||||