Primary Site >> Colorectal Cancer
Gene >> CDK19
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Ref: Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. PMID: 22308110 |
Ref: Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19. PMID: 26796641 Ref: Discovery of potent and selective CDK8 inhibitors from an HSP90 pharmacophore. PMID: 26852363 |
Ref: Pharmacogenomic Characterization and Isobologram Analysis of the Combination of Ascorbic Acid and Curcumin-Two Main Metabolites of Curcuma longa-in Cancer Cells. PMID: 28210221 Ref: CDK8 Kinase Activity Promotes Glycolysis. PMID: 29117556 |
Ref: Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19. PMID: 29440396 Ref: Depletion of Mediator Kinase Module Subunits Represses Superenhancer-Associated Genes in Colon Cancer Cells. PMID: 29507187 |