Primary Site >> Biliary tract Cancer

Gene >> CDH2

Journal: Gastroenterology. 1996 Apr;110(4):1137-49.
Title: Expression of cadherins and alpha-catenin in primary epithelial tumors of the liver.
Author: Kozyraki, R|Scoazec, J Y|Flejou, J F|D'Errico, A|Bedossa, P|Terris, B|Fiorentino, M|Bringuier, A F|Grigioni, W F|Feldmann, G
PMID: 8613003
Journal: Mod Pathol. 2009 Feb;22(2):182-90.
Title: N-cadherin serves as diagnostic biomarker in intrahepatic and perihilar cholangiocarcinomas.
Author: Mosnier, Jean-Francois|Kandel, Christine|Cazals-Hatem, Dominique|Bou-Hanna, Chantal|Gournay, Jerome|Jarry, Anne|Laboisse, Christian L
PMID: 18622386
Journal: Mod Pathol. 2011 Jun;24(6):810-9.
Title: Viral hepatitis is associated with intrahepatic cholangiocarcinoma with cholangiolar differentiation and N-cadherin expression.
Author: Yu, Tsan-Hua|Yuan, Ray-Hwang|Chen, Yu-Ling|Yang, Wan-Ching|Hsu, Hey-Chi|Jeng, Yung-Ming
PMID: 21423153
Journal: Br J Cancer. 2011 Dec 6;105(12):1885-93.
Title: E/N-cadherin switch mediates cancer progression via TGF-beta-induced epithelial-to-mesenchymal transition in extrahepatic cholangiocarcinoma.
Author: Araki, K|Shimura, T|Suzuki, H|Tsutsumi, S|Wada, W|Yajima, T|Kobayahi, T|Kubo, N|Kuwano, H
PMID: 22068819
Journal: Hum Pathol. 2012 Oct;43(10):1583-9.
Title: The novel monoclonal antibody HPC2 and N-cadherin distinguish pancreatic ductal adenocarcinoma from cholangiocarcinoma.
Author: Hooper, Jody E|Morgan, Terry K|Grompe, Markus|Sheppard, Brett C|Troxell, Megan L|Corless, Christopher L|Streeter, Philip R
PMID: 22406361
Journal: Histopathology. 2012 Dec;61(6):1106-16.
Title: S100P immunostaining identifies a subset of peripheral-type intrahepatic cholangiocarcinomas with morphological and molecular features similar to those of perihilar and extrahepatic cholangiocarcinomas.
Author: Tsai, Jia-Huei|Huang, Wen-Chih|Kuo, Kuan-Ting|Yuan, Ray-Hwang|Chen, Yu-Ling|Jeng, Yung-Ming
PMID: 22882148
Journal: Onco Targets Ther. 2012;5:255-61.
Title: Clinicopathological and prognostic significance of epithelial mesenchymal transition-related protein expression in intrahepatic cholangiocarcinoma.
Author: Yao, Xing|Wang, Xiang|Wang, Zishu|Dai, Licheng|Zhang, Guolei|Yan, Qiang|Zhou, Weimin
PMID: 23091390
Journal: Eur J Cancer. 2013 May;49(7):1725-40.
Title: Role of crosstalk between interleukin-6 and transforming growth factor-beta 1 in epithelial-mesenchymal transition and chemoresistance in biliary tract cancer.
Author: Yamada, Daisaku|Kobayashi, Shogo|Wada, Hiroshi|Kawamoto, Koichi|Marubashi, Shigeru|Eguchi, Hidetoshi|Ishii, Hideshi|Nagano, Hiroaki|Doki, Yuichiro|Mori, Masaki
PMID: 23298711
Journal: Cancer Sci. 2013 Nov;104(11):1427-32.
Title: Forkhead box protein C2 contributes to invasion and metastasis of extrahepatic cholangiocarcinoma, resulting in a poor prognosis.
Author: Watanabe, Akira|Suzuki, Hideki|Yokobori, Takehiko|Altan, Bolag|Kubo, Norio|Araki, Kenichiro|Wada, Satoshi|Mochida, Yasushi|Sasaki, Shigeru|Kashiwabara, Kenji|Hosouchi, Yasuo|Kuwano, Hiroyuki
PMID: 23919841
Journal: Mod Pathol. 2014 Aug;27(8):1163-73.
Title: Morphological subclassification of intrahepatic cholangiocarcinoma: etiological, clinicopathological, and molecular features.
Author: Liau, Jau-Yu|Tsai, Jia-Huei|Yuan, Ray-Hwang|Chang, Chih-Ning|Lee, Hsin-Jung|Jeng, Yung-Ming
PMID: 24406866
Journal: Pathol Res Pract. 2014 Jun;210(6):363-8.
Title: N-cadherin and P-cadherin are biomarkers for invasion, metastasis, and poor prognosis of gallbladder carcinomas.
Author: Yi, Shengen|Yang, Zhu-Lin|Miao, Xiongying|Zou, Qiong|Li, Jinghe|Liang, Lufeng|Zeng, Guixiang|Chen, Senlin
PMID: 24636838
Journal: J Hepatol. 2014 Aug;61(2):325-32.
Title: EGF/EGFR axis contributes to the progression of cholangiocarcinoma through the induction of an epithelial-mesenchymal transition.
Author: Claperon, Audrey|Mergey, Martine|Nguyen Ho-Bouldoires, Thanh Huong|Vignjevic, Danijela|Wendum, Dominique|Chretien, Yves|Merabtene, Fatiha|Frazao, Alexandra|Paradis, Valerie|Housset, Chantal|Guedj, Nathalie|Fouassier, Laura
PMID: 24704591
Journal: Tumour Biol. 2014 Oct;35(10):9667-76.
Title: BMP-7 blocks the effects of TGF-beta-induced EMT in cholangiocarcinoma.
Author: Duangkumpha, Kassaporn|Techasen, Anchalee|Loilome, Watcharin|Namwat, Nisana|Thanan, Raynoo|Khuntikeo, Narong|Yongvanit, Puangrat
PMID: 24969562
Journal: Br J Cancer. 2014 Sep 23;111(7):1363-72.
Title: Prognostic significance of epithelial-mesenchymal transition-related markers in extrahepatic cholangiocarcinoma: comprehensive immunohistochemical study using a tissue microarray.
Author: Nitta, T|Mitsuhashi, T|Hatanaka, Y|Miyamoto, M|Oba, K|Tsuchikawa, T|Suzuki, Y|Hatanaka, K C|Hirano, S|Matsuno, Y
PMID: 25077440
Journal: BMC Cancer. 2014 Oct 25;14:783.
Title: FTY720 inhibits proliferation and epithelial-mesenchymal transition in cholangiocarcinoma by inactivating STAT3 signaling.
Author: Lu, Zhaoyang|Wang, Jiabei|Zheng, Tongsen|Liang, Yingjian|Yin, Dalong|Song, Ruipeng|Pei, Tiemin|Pan, Shangha|Jiang, Hongchi|Liu, Lianxin
PMID: 25344679
Journal: Oncol Rep. 2015 Aug;34(2):610-6.
Title: Adrenomedullin promotes intrahepatic cholangiocellular carcinoma metastasis and invasion by inducing epithelial-mesenchymal transition.
Author: Zhou, Chuang|Zheng, Yan|Li, Lin|Zhai, Wenlong|Li, Renfeng|Liang, Zhiwen|Zhao, Longshuan
PMID: 26043778
Journal: Asian Pac J Cancer Prev. 2015;16(7):3043-50.
Title: Quantitative changes in tumor-associated M2 macrophages characterize cholangiocarcinoma and their association with metastasis.
Author: Thanee, Malinee|Loilome, Watcharin|Techasen, Anchalee|Namwat, Nisana|Boonmars, Thidarut|Pairojkul, Chawalit|Yongvanit, Puangrat
PMID: 25854403
Journal: Med Oncol. 2015 Apr;32(4):105.
Title: Enhanced expression of suppresser of cytokine signaling 3 inhibits the IL-6-induced epithelial-to-mesenchymal transition and cholangiocarcinoma cell metastasis.
Author: Zhou, Qing-Xin|Jiang, Xing-Ming|Wang, Zhi-Dong|Li, Chun-Long|Cui, Yun-Fu
PMID: 25744243
Journal: PLoS One. 2016 Jan 4;11(1):e0145985.
Title: A Histone Deacetylase Inhibitor Suppresses Epithelial-Mesenchymal Transition and Attenuates Chemoresistance in Biliary Tract Cancer.
Author: Sakamoto, Takuya|Kobayashi, Shogo|Yamada, Daisaku|Nagano, Hiroaki|Tomokuni, Akira|Tomimaru, Yoshito|Noda, Takehiro|Gotoh, Kunihito|Asaoka, Tadafumi|Wada, Hiroshi|Kawamoto, Koichi|Marubashi, Shigeru|Eguchi, Hidetoshi|Doki, Yuichiro|Mori, Masaki
PMID: 26726879
Journal: Am J Surg Pathol. 2016 Aug;40(8):1021-30.
Title: Distinct Clinicopathologic and Genetic Features of 2 Histologic Subtypes of Intrahepatic Cholangiocarcinoma.
Author: Hayashi, Akimasa|Misumi, Kento|Shibahara, Junji|Arita, Junichi|Sakamoto, Yoshihiro|Hasegawa, Kiyoshi|Kokudo, Norihiro|Fukayama, Masashi
PMID: 27259014
Journal: PLoS One. 2016 Jun 9;11(6):e0157140.
Title: Expression of Molecular Differentiation Markers Does Not Correlate with Histological Differentiation Grade in Intrahepatic Cholangiocarcinoma.
Author: Demarez, Celine|Hubert, Catherine|Sempoux, Christine|Lemaigre, Frederic P
PMID: 27280413
Journal: Histopathology. 2017 Apr;70(5):766-774.
Title: Intrahepatic cholangiocarcinoma frequently shows loss of BAP1 and PBRM1 expression, and demonstrates specific clinicopathological and genetic characteristics with BAP1 loss.
Author: Misumi, Kento|Hayashi, Akimasa|Shibahara, Junji|Arita, Junichi|Sakamoto, Yoshihiro|Hasegawa, Kiyoshi|Kokudo, Norihiro|Fukayama, Masashi
PMID: 27864835
Journal: Chem Biol Drug Des. 2017 Sep;90(3):456-463.
Title: The NmrA-like family domain containing 1 pseudogene Loc344887 is amplified in gallbladder cancer and promotes epithelial-mesenchymal transition.
Author: Wu, Xiao-Cai|Wang, Shou-Hua|Ou, Hong-Hui|Zhu, Bing|Zhu, Yong|Zhang, Qi|Yang, Yang|Li, Hua
PMID: 28245089
Journal: Oncotarget. 2017 Jul 25;8(30):49897-49914.
Title: Ring finger protein 125, as a potential highly aggressive and unfavorable prognostic biomarker, promotes the invasion and metastasis of human gallbladder cancers via activating the TGF- beta1-SMAD3-ID1 signaling pathway.
Author: Liu, Zhong-Yan|Cao, Jin|Zhang, Jing-Tao|Xu, Guo-Li|Li, Xin-Ping|Wang, Fang-Tao|Ansari, Kamar Hasan|Mohamed, Hassan|Fan, Yue-Zu
PMID: 28611292
Journal: PLoS One. 2017 Sep 5;12(9):e0183932.
Title: TGF-beta signaling is an effective target to impair survival and induce apoptosis of human cholangiocarcinoma cells: A study on human primary cell cultures.
Author: Lustri, Anna Maria|Di Matteo, Sabina|Fraveto, Alice|Costantini, Daniele|Cantafora, Alfredo|Napoletano, Chiara|Bragazzi, Maria Consiglia|Giuliante, Felice|De Rose, Agostino M|Berloco, Pasquale B|Grazi, Gian Luca|Carpino, Guido|Alvaro, Domenico
PMID: 28873435
Journal: Am J Surg Pathol. 2017 Dec;41(12):1630-1641.
Title: C-Reactive Protein (CRP) is a Promising Diagnostic Immunohistochemical Marker for Intrahepatic Cholangiocarcinoma and is Associated With Better Prognosis.
Author: Yeh, Yi-Chen|Lei, Hao-Jan|Chen, Ming-Huang|Ho, Hsiang-Ling|Chiu, Ling-Ya|Li, Chung-Pin|Wang, Yu-Chao
PMID: 28945626
Journal: Tumour Biol. 2017 Nov;39(11):1010428317725925.
Title: Establishment of cholangiocarcinoma cell lines from patients in the endemic area of liver fluke infection in Thailand.
Author: Saensa-Ard, Sunitta|Leuangwattanawanit, Saman|Senggunprai, Laddawan|Namwat, Nisana|Kongpetch, Sarinya|Chamgramol, Yaovalux|Loilome, Watcharin|Khansaard, Walaiporn|Jusakul, Apinya|Prawan, Auemduan|Pairojkul, Chawalit|Khantikeo, Narong|Yongvanit, Puangrat|K
PMID: 29110582
Journal: Hepatol Commun. 2017 Oct 25;1(10):1099-1109.
Title: Periostin promotes malignant potential by induction of epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma.
Author: Mino, Masaaki|Kanno, Keishi|Okimoto, Kousuke|Sugiyama, Akiko|Kishikawa, Nobusuke|Kobayashi, Tomoki|Ono, Junya|Izuhara, Kenji|Kobayashi, Tsuyoshi|Ohigashi, Toshikazu|Ohdan, Hideki|Tazuma, Susumu
PMID: 29404445
Journal: Liver Int. 2018 Jan;38(1):113-124.
Title: Transcriptomic and histopathological analysis of cholangiolocellular differentiation trait in intrahepatic cholangiocarcinoma.
Author: Rhee, Hyungjin|Ko, Jung Eun|Chung, Taek|Jee, Byul A|Kwon, So Mee|Nahm, Ji Hae|Seok, Jae Yeon|Yoo, Jeong Eun|Choi, Jin-Sub|Thorgeirsson, Snorri S|Andersen, Jesper B|Lee, Hye Sun|Woo, Hyun Goo|Park, Young Nyun
PMID: 28608943
Journal: Cell Death Dis. 2018 Jan 22;9(2):71.
Title: PLZF inhibits proliferation and metastasis of gallbladder cancer by regulating IFIT2.
Author: Shen, Hui|Zhan, Ming|Zhang, Yonglong|Huang, Shuai|Xu, Sunwang|Huang, Xince|He, Min|Yao, Yanhua|Man, Mohan|Wang, Jian
PMID: 29358655
Journal: Oncotarget. 2018 Apr 13;9(28):20034-20047.
Title: Prognostic impact of programmed cell death ligand 1 (PD-L1) expression and its association with epithelial-mesenchymal transition in extrahepatic cholangiocarcinoma.
Author: Ueno, Takashi|Tsuchikawa, Takahiro|Hatanaka, Kanako C|Hatanaka, Yutaka|Mitsuhashi, Tomoko|Nakanishi, Yoshitsugu|Noji, Takehiro|Nakamura, Toru|Okamura, Keisuke|Matsuno, Yoshihiro|Hirano, Satoshi
PMID: 29732001
Journal: Zhonghua Wai Ke Za Zhi. 2018 Aug 1;56(8):617-622.
Title: [Kindlin-2 promotes gallbladder cancer metastasis and invasion by inducing epithelial-mesenchymal transition].
Author: Lu, X|Zhou, C|Li, R F|Ye, J W|Zhai, W L
PMID: 30107706
Journal: Virchows Arch. 2018 Oct 23. pii: 10.1007/s00428-018-2476-0.
Title: EVI1 expression is associated with aggressive behavior in intrahepatic cholangiocarcinoma.
Author: Tanaka, Mariko|Shibahara, Junji|Ishikawa, Shumpei|Ushiku, Tetsuo|Morikawa, Teppei|Shinozaki-Ushiku, Aya|Hayashi, Akimasa|Misumi, Kento|Tanaka, Atsushi|Katoh, Hiroto|Sakuma, Kei|Kokudo, Takashi|Inagaki, Yoshinori|Arita, Junichi|Sakamoto, Yoshihiro|Hasegawa
PMID: 30349952