Primary Site >> Biliary tract Cancer

Gene >> CDH2

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Ref: Expression of cadherins and alpha-catenin in primary epithelial tumors of the liver.
PMID: 8613003
 Ref: N-cadherin serves as diagnostic biomarker in intrahepatic and perihilar cholangiocarcinomas.
PMID: 18622386
 Ref: Viral hepatitis is associated with intrahepatic cholangiocarcinoma with cholangiolar differentiation and N-cadherin expression.
PMID: 21423153
Ref: E/N-cadherin switch mediates cancer progression via TGF-beta-induced epithelial-to-mesenchymal transition in extrahepatic cholangiocarcinoma.
PMID: 22068819
 Ref: The novel monoclonal antibody HPC2 and N-cadherin distinguish pancreatic ductal adenocarcinoma from cholangiocarcinoma.
PMID: 22406361
Ref: S100P immunostaining identifies a subset of peripheral-type intrahepatic cholangiocarcinomas with morphological and molecular features similar to those of perihilar and extrahepatic cholangiocarcinomas.
PMID: 22882148
Ref: Clinicopathological and prognostic significance of epithelial mesenchymal transition-related protein expression in intrahepatic cholangiocarcinoma.
PMID: 23091390
 Ref: Role of crosstalk between interleukin-6 and transforming growth factor-beta 1 in epithelial-mesenchymal transition and chemoresistance in biliary tract cancer.
PMID: 23298711
Ref: Forkhead box protein C2 contributes to invasion and metastasis of extrahepatic cholangiocarcinoma, resulting in a poor prognosis.
PMID: 23919841
 Ref: Morphological subclassification of intrahepatic cholangiocarcinoma: etiological, clinicopathological, and molecular features.
PMID: 24406866
Ref: N-cadherin and P-cadherin are biomarkers for invasion, metastasis, and poor prognosis of gallbladder carcinomas.
PMID: 24636838
Ref: EGF/EGFR axis contributes to the progression of cholangiocarcinoma through the induction of an epithelial-mesenchymal transition.
PMID: 24704591
Ref: BMP-7 blocks the effects of TGF-beta-induced EMT in cholangiocarcinoma.
PMID: 24969562
Ref: Prognostic significance of epithelial-mesenchymal transition-related markers in extrahepatic cholangiocarcinoma: comprehensive immunohistochemical study using a tissue microarray.
PMID: 25077440
Ref: FTY720 inhibits proliferation and epithelial-mesenchymal transition in cholangiocarcinoma by inactivating STAT3 signaling.
PMID: 25344679
 Ref: Enhanced expression of suppresser of cytokine signaling 3 inhibits the IL-6-induced epithelial-to-mesenchymal transition and cholangiocarcinoma cell metastasis.
PMID: 25744243
Ref: Quantitative changes in tumor-associated M2 macrophages characterize cholangiocarcinoma and their association with metastasis.
PMID: 25854403
Ref: Adrenomedullin promotes intrahepatic cholangiocellular carcinoma metastasis and invasion by inducing epithelial-mesenchymal transition.
PMID: 26043778
 Ref: A Histone Deacetylase Inhibitor Suppresses Epithelial-Mesenchymal Transition and Attenuates Chemoresistance in Biliary Tract Cancer.
PMID: 26726879
Ref: Distinct Clinicopathologic and Genetic Features of 2 Histologic Subtypes of Intrahepatic Cholangiocarcinoma.
PMID: 27259014
Ref: Expression of Molecular Differentiation Markers Does Not Correlate with Histological Differentiation Grade in Intrahepatic Cholangiocarcinoma.
PMID: 27280413
 Ref: Intrahepatic cholangiocarcinoma frequently shows loss of BAP1 and PBRM1 expression, and demonstrates specific clinicopathological and genetic characteristics with BAP1 loss.
PMID: 27864835
Ref: The NmrA-like family domain containing 1 pseudogene Loc344887 is amplified in gallbladder cancer and promotes epithelial-mesenchymal transition.
PMID: 28245089
Ref: Ring finger protein 125, as a potential highly aggressive and unfavorable prognostic biomarker, promotes the invasion and metastasis of human gallbladder cancers via activating the TGF- beta1-SMAD3-ID1 signaling pathway.
PMID: 28611292
Ref: TGF-beta signaling is an effective target to impair survival and induce apoptosis of human cholangiocarcinoma cells: A study on human primary cell cultures.
PMID: 28873435
Ref: C-Reactive Protein (CRP) is a Promising Diagnostic Immunohistochemical Marker for Intrahepatic Cholangiocarcinoma and is Associated With Better Prognosis.
PMID: 28945626
Ref: Establishment of cholangiocarcinoma cell lines from patients in the endemic area of liver fluke infection in Thailand.
PMID: 29110582
Ref: Periostin promotes malignant potential by induction of epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma.
PMID: 29404445
 Ref: Transcriptomic and histopathological analysis of cholangiolocellular differentiation trait in intrahepatic cholangiocarcinoma.
PMID: 28608943
Ref: PLZF inhibits proliferation and metastasis of gallbladder cancer by regulating IFIT2.
PMID: 29358655
Ref: Prognostic impact of programmed cell death ligand 1 (PD-L1) expression and its association with epithelial-mesenchymal transition in extrahepatic cholangiocarcinoma.
PMID: 29732001
Ref: [Kindlin-2 promotes gallbladder cancer metastasis and invasion by inducing epithelial-mesenchymal transition].
PMID: 30107706
Ref: EVI1 expression is associated with aggressive behavior in intrahepatic cholangiocarcinoma.
PMID: 30349952