Primary Site >> Stomach Cancer

Gene >> CDH1

Journal:
Title: Hereditary Diffuse Gastric Cancer
Author: Kaurah, Pardeep|Huntsman, David G
PMID: 20301318
Journal: Cancer. 1995 Sep 15;76(6):941-53.
Title: E-cadherin and urokinase-type plasminogen activator tissue status in gastric carcinoma.
Author: Yonemura, Y|Nojima, N|Kaji, M|Fujimura, T|Itoh, H|Ninomiya, I|Miyazaki, I|Endo, Y|Sasaki, T
PMID: 8625219
Journal: Hum Mutat. 1998;12(4):226-37.
Title: Mutations of the human E-cadherin (CDH1) gene.
Author: Berx, G|Becker, K F|Hofler, H|van Roy, F
PMID: 9744472
Journal: Hum Mol Genet. 1999 Apr;8(4):607-10.
Title: Germline E-cadherin gene (CDH1) mutations predispose to familial gastric cancer and colorectal cancer.
Author: Richards, F M|McKee, S A|Rajpar, M H|Cole, T R|Evans, D G|Jankowski, J A|McKeown, C|Sanders, D S|Maher, E R
PMID: 10072428
Journal: Hum Mutat. 1999;13(2):171.
Title: Identification of eleven novel tumor-associated E-cadherin mutations. Mutations in brief no. 215. Online.
Author: Becker, K F|Reich, U|Schott, C|Becker, I|Berx, G|van Roy, F|Hofler, H
PMID: 10094558
Journal: Am J Pathol. 1999 Aug;155(2):337-42.
Title: Diffuse type gastric and lobular breast carcinoma in a familial gastric cancer patient with an E-cadherin germline mutation.
Author: Keller, G|Vogelsang, H|Becker, I|Hutter, J|Ott, K|Candidus, S|Grundei, T|Becker, K F|Mueller, J|Siewert, J R|Hofler, H
PMID: 10433926
Journal: J Med Genet. 1999 Dec;36(12):873-80.
Title: Familial gastric cancer: overview and guidelines for management.
Author: Caldas, C|Carneiro, F|Lynch, H T|Yokota, J|Wiesner, G L|Powell, S M|Lewis, F R|Huntsman, D G|Pharoah, P D|Jankowski, J A|MacLeod, P|Vogelsang, H|Keller, G|Park, K G|Richards, F M|Maher, E R|Gayther, S A|Oliveira, C|Grehan, N|Wight, D|Seruca, R|Roviello, F
PMID: 10593993
Journal: Gut. 2000 Aug;47(2):262-7.
Title: The E-cadherin gene (CDH1) variants T340A and L599V in gastric and colorectal cancer patients in Korea.
Author: Kim, H C|Wheeler, J M|Kim, J C|Ilyas, M|Beck, N E|Kim, B S|Park, K C|Bodmer, W F
PMID: 10896919
Journal: Nat Genet. 2000 Sep;26(1):16-7.
Title: Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer.
Author: Grady, W M|Willis, J|Guilford, P J|Dunbier, A K|Toro, T T|Lynch, H|Wiesner, G|Ferguson, K|Eng, C|Park, J G|Kim, S J|Markowitz, S
PMID: 10973239
Journal: Oncogene. 2001 Mar 22;20(12):1525-8.
Title: E-cadherin gene (CDH1) promoter methylation as the second hit in sporadic diffuse gastric carcinoma.
Author: Machado, J C|Oliveira, C|Carvalho, R|Soares, P|Berx, G|Caldas, C|Seruca, R|Carneiro, F|Sobrinho-Simoes, M
PMID: 11313896
Journal: N Engl J Med. 2001 Jun 21;344(25):1904-9.
Title: Early gastric cancer in young, asymptomatic carriers of germ-line E-cadherin mutations.
Author: Huntsman, D G|Carneiro, F|Lewis, F R|MacLeod, P M|Hayashi, A|Monaghan, K G|Maung, R|Seruca, R|Jackson, C E|Caldas, C
PMID: 11419427
Journal: Eur J Gastroenterol Hepatol. 2001 Jun;13(6):711-5.
Title: A new mutation of E-cadherin gene in familial gastric linitis plastica cancer with extra-digestive dissemination.
Author: Dussaulx-Garin, L|Blayau, M|Pagenault, M|Le Berre-Heresbach, N|Raoul, J L|Campion, J P|David, V|Bretagne, J F
PMID: 11434599
Journal: Cancer. 2001 Jul 1;92(1):181-7.
Title: Germline E-cadherin gene mutations: is prophylactic total gastrectomy indicated?
Author: Chun, Y S|Lindor, N M|Smyrk, T C|Petersen, B T|Burgart, L J|Guilford, P J|Donohue, J H
PMID: 11443625
Journal: Oncol Rep. 2001 Sep-Oct;8(5):1085-9.
Title: DNA methylation status of hMLH1, p16(INK4a), and CDH1 is not associated with mRNA expression levels of DNA methyltransferase and DNA demethylase in gastric carcinomas.
Author: Oue, N|Kuraoka, K|Kuniyasu, H|Yokozaki, H|Wakikawa, A|Matsusaki, K|Yasui, W
PMID: 11496321
Journal: Int J Mol Med. 2001 Oct;8(4):439-43.
Title: A germline E-cadherin mutation in a family with gastric and colon cancer.
Author: Salahshor, S|Hou, H|Diep, C B|Loukola, A|Zhang, H|Liu, T|Chen, J|Iselius, L|Rubio, C|Lothe, R A|Aaltonen, L|Sun, X F|Lindmark, G|Lindblom, A
PMID: 11562785
Journal: Surgery. 2001 Oct;130(4):612-7; discussion 617-9.
Title: Prophylactic total gastrectomy for familial gastric cancer.
Author: Lewis, F R|Mellinger, J D|Hayashi, A|Lorelli, D|Monaghan, K G|Carneiro, F|Huntsman, D G|Jackson, C E|Caldas, C
PMID: 11602891
Journal: Exp Toxicol Pathol. 2001 Sep;53(4):237-46.
Title: Loss of E-cadherin expression in gastric intestinal metaplasia and later stage p53 altered expression in gastric carcinogenesis.
Author: Mingchao|Devereux, T R|Stockton, P|Sun, K|Sills, R C|Clayton, N|Portier, M|Flake, G
PMID: 11665847
Journal: Clin Cancer Res. 2001 Nov;7(11):3465-71.
Title: Association of E-cadherin germ-line alterations with prostate cancer.
Author: Ikonen, T|Matikainen, M|Mononen, N|Hyytinen, E R|Helin, H J|Tommola, S|Tammela, T L|Pukkala, E|Schleutker, J|Kallioniemi, O P|Koivisto, P A
PMID: 11705864
Journal: Gastroenterology. 2001 Dec;121(6):1348-53.
Title: Incidence of gastric cancer and breast cancer in CDH1 (E-cadherin) mutation carriers from hereditary diffuse gastric cancer families.
Author: Pharoah, P D|Guilford, P|Caldas, C
PMID: 11729114
Journal: Oncogene. 2002 Mar 14;21(12):1928-33.
Title: Contribution of cyclin d1 (CCND1) and E-cadherin (CDH1) polymorphisms to familial and sporadic colorectal cancer.
Author: Porter, Timothy R|Richards, Frances M|Houlston, Richard S|Evans, D Gareth R|Jankowski, Janusz A|Macdonald, Fiona|Norbury, Gail|Payne, Stewart J|Fisher, Samantha A|Tomlinson, Ian|Maher, Eamonn R
PMID: 11896626
Journal: Int J Cancer. 2002 Apr 20;98(6):838-43.
Title: Germline mutations in E-cadherin do not explain association of hereditary prostate cancer, gastric cancer and breast cancer.
Author: Jonsson, Bjorn-Anders|Bergh, Anders|Stattin, Par|Emmanuelsson, Monika|Gronberg, Henrik
PMID: 11948460
Journal: Hum Mutat. 2002 May;19(5):510-7.
Title: Screening E-cadherin in gastric cancer families reveals germline mutations only in hereditary diffuse gastric cancer kindred.
Author: Oliveira, Carla|Bordin, Maria Cristina|Grehan, Nicola|Huntsman, David|Suriano, Gianpaolo|Machado, Jose Carlos|Kiviluoto, Tuula|Aaltonen, Lauri|Jackson, Charles E|Seruca, Raquel|Caldas, Carlos
PMID: 11968083
Journal: Hum Mutat. 2002 May;19(5):518-25.
Title: Novel germline CDH1 mutations in hereditary diffuse gastric cancer families.
Author: Humar, Bostjan|Toro, Tumi|Graziano, Francesco|Muller, Hansjakob|Dobbie, Zuzana|Kwang-Yang, Han|Eng, Charis|Hampel, Heather|Gilbert, Dale|Winship, Ingrid|Parry, Susan|Ward, Robyn|Findlay, Mike|Christian, Alice|Tucker, Monica|Tucker, Kathy|Merriman, Tony|Gu
PMID: 11968084
Journal: Semin Radiat Oncol. 2002 Apr;12(2):128-40.
Title: Molecular biology of gastric cancer.
Author: El-Rifai, Wa'el|Powell, Steven M
PMID: 11979414
Journal: Clin J Oncol Nurs. 2002 May-Jun;6(3):161-2.
Title: Prophylactic gastrectomy for CDH1 mutation carriers.
Author: Giarelli, Ellen
PMID: 11998610
Journal: Dig Dis. 2002;20(1):23-31.
Title: E-cadherin mutations and hereditary gastric cancer: prevention by resection?
Author: Fitzgerald, R C|Caldas, C
PMID: 12145417
Journal: Int J Cancer. 2002 Sep 10;101(2):196-7.
Title: CDH1 c-160a promotor polymorphism is not associated with risk of stomach cancer.
Author: Pharoah, Paul D P|Oliveira, Carla|Machado, Jose Carlos|Keller, Gisella|Vogelsang, Holger|Laux, Holger|Becker, Karl-Friedrich|Hahn, Heidi|Paproski, Suzanne M|Brown, Lindsay A|Caldas, Carlos|Huntsman, David
PMID: 12209998
Journal: Oncogene. 2002 Nov 21;21(53):8192-5.
Title: Association of CDH1 haplotypes with susceptibility to sporadic diffuse gastric cancer.
Author: Humar, Bostjan|Graziano, Francesco|Cascinu, Stefano|Catalano, Vincenzo|Ruzzo, Anna M|Magnani, Mauro|Toro, Tumi|Burchill, Tudor|Futschik, Matthias E|Merriman, Tony|Guilford, Parry
PMID: 12444556
Journal: Int J Mol Med. 2003 Mar;11(3):383-8.
Title: Identification and characterization of human SNAIL3 (SNAI3) gene in silico.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 12579345
Journal: Hum Mol Genet. 2003 Mar 1;12(5):575-82.
Title: Identification of CDH1 germline missense mutations associated with functional inactivation of the E-cadherin protein in young gastric cancer probands.
Author: Suriano, Gianpaolo|Oliveira, Carla|Ferreira, Paulo|Machado, Jose C|Bordin, Maria C|De Wever, Olivier|Bruyneel, Erik A|Moguilevsky, Nicole|Grehan, Nicola|Porter, Timothy R|Richards, Frances M|Hruban, Ralph H|Roviello, Franco|Huntsman, David|Mareel, Marc|Ca
PMID: 12588804
Journal: Jpn J Clin Oncol. 2003 Jan;33(1):17-20.
Title: Ile-Leu substitution (I415L) in germline E-cadherin gene (CDH1) in Japanese familial gastric cancer.
Author: Wang, Ying|Song, Jian-Ping|Ikeda, Masami|Shinmura, Kazuya|Yokota, Jun|Sugimura, Haruhiko
PMID: 12604719
Journal: Langenbecks Arch Surg. 2003 Mar;388(1):27-32. Epub 2003 Feb 19.
Title: Preventive gastrectomy in patients with gastric cancer risk due to genetic alterations of the E-cadherin gene defect.
Author: Schwarz, A
PMID: 12690477
Journal: Eur J Cancer. 2003 Jun;39(9):1222-7.
Title: Concurrent hypermethylation of gene promoters is associated with a MSI-H phenotype and diploidy in gastric carcinomas.
Author: Carvalho, B|Pinto, M|Cirnes, L|Oliveira, C|Machado, J C|Suriano, G|Hamelin, R|Carneiro, F|Seruca, R
PMID: 12763209
Journal: Tumori. 2003 May-Jun;89(3):255-8.
Title: Screening E-cadherin germline mutations in Italian patients with familial diffuse gastric cancer: an analysis in the District of Urbino, Region Marche, Central Italy.
Author: Graziano, Francesco|Ruzzo, Anna Maria|Bearzi, Italo|Testa, Enrica|Lai, Vittorio|Magnani, Mauro
PMID: 12908778
Journal: Rev Gastroenterol Mex. 2003 Jan-Mar;68(1):51-4.
Title: [Hereditary gastric cancer. Genetics and clinical management].
Author: Medina-Franco, Heriberto
PMID: 12940100
Journal: Cancer Sci. 2003 Oct;94(10):901-5.
Title: DNA methylation of multiple genes in gastric carcinoma: association with histological type and CpG island methylator phenotype.
Author: Oue, Naohide|Oshimo, Yasuhiro|Nakayama, Hirofumi|Ito, Reiko|Yoshida, Kazuhiro|Matsusaki, Keisuke|Yasui, Wataru
PMID: 14556664
Journal: Tumour Biol. 2003 May-Jun;24(3):147-50.
Title: The G/A nucleotide change at cDNA position 2494 in the E-cadherin gene (CDH1): analysis in Italian patients.
Author: Ruzzo, Annamaria|Graziano, Francesco|Costagliola, Antonello|Arduini, Federica|Testa, Enrica|Bearzi, Italo|Cortese, Giuliana|De Gaetano, Andrea|Andreoni, Francesca|Lai, Vittorio|Magnani, Mauro
PMID: 14610318
Journal: Ann Oncol. 2003 Dec;14(12):1705-13.
Title: The role of the E-cadherin gene (CDH1) in diffuse gastric cancer susceptibility: from the laboratory to clinical practice.
Author: Graziano, F|Humar, B|Guilford, P
PMID: 14630673
Journal: Arq Gastroenterol. 2003 Apr-Jun;40(2):114-7. Epub 2004 Jan 16.
Title: Familial gastric cancer.
Author: Bresciani, Claudio|Perez, Rodrigo Oliva|Gama-Rodrigues, Joaquim
PMID: 14762482
Journal: Oncogene. 2004 Mar 18;23(12):2236-40.
Title: Intragenic deletion of CDH1 as the inactivating mechanism of the wild-type allele in an HDGC tumour.
Author: Oliveira, Carla|de Bruin, Joyce|Nabais, Sergio|Ligtenberg, Marjolijn|Moutinho, Catia|Nagengast, Fokko M|Seruca, Raquel|van Krieken, Han|Carneiro, Fatima
PMID: 14661064
Journal: Ann Oncol. 2004 Mar;15(3):489-92.
Title: Combined analysis of E-cadherin gene (CDH1) promoter hypermethylation and E-cadherin protein expression in patients with gastric cancer: implications for treatment with demethylating drugs.
Author: Graziano, F|Arduini, F|Ruzzo, A|Mandolesi, A|Bearzi, I|Silva, R|Muretto, P|Testa, E|Mari, D|Magnani, M|Scartozzi, M|Cascinu, S
PMID: 14998854
Journal: Hepatogastroenterology. 2004 Jan-Feb;51(55):320-7.
Title: Genes and gastric cancer.
Author: Kyrlagkitsis, Ioannis|Karamanolis, D G
PMID: 15011894
Journal: Int J Colorectal Dis. 2004 Nov;19(6):561-8. Epub 2004 Apr 9.
Title: Geno- and pheno-typic characterization in ten patients with double-primary gastric and colorectal adenocarcinomas.
Author: Kim, Jin C|Koo, Kum H|Kim, Hee C|Kim, Jung S|Kang, Gyeong H
PMID: 15083323
Journal: Clin Cancer Res. 2004 Apr 15;10(8):2784-9.
Title: Prognostic analysis of E-cadherin gene promoter hypermethylation in patients with surgically resected, node-positive, diffuse gastric cancer.
Author: Graziano, Francesco|Arduini, Federica|Ruzzo, Annamaria|Bearzi, Italo|Humar, Bostjan|More, Helen|Silva, Rosarita|Muretto, Pietro|Guilford, Parry|Testa, Enrica|Mari, Davide|Magnani, Mauro|Cascinu, Stefano
PMID: 15102685
Journal: Eur J Surg Oncol. 2004 Jun;30(5):531-5.
Title: Germline mutational analysis of CDH1 and pathologic features in familial cancer syndrome with diffuse gastric cancer/breast cancer proband in a Chinese family.
Author: Zhu, Z G|Yu, Y Y|Zhang, Y|Ji, J|Zhang, J|Liu, B Y|Chen, X H|Lu, Y|Jiang, H S|Bu, L|Hu, L D|Kong, X Y
PMID: 15135482
Journal: J Med Genet. 2004 Jun;41(6):e89.
Title: Germline mutations of the E-cadherin(CDH1) and TP53 genes, rather than of RUNX3 and HPP1, contribute to genetic predisposition in German gastric cancer patients.
Author: Keller, G|Vogelsang, H|Becker, I|Plaschke, S|Ott, K|Suriano, G|Mateus, A R|Seruca, R|Biedermann, K|Huntsman, D|Doring, C|Holinski-Feder, E|Neutzling, A|Siewert, J R|Hofler, H
PMID: 15173255
Journal: J Med Genet. 2004 Jul;41(7):508-17.
Title: Germline E-cadherin mutations in hereditary diffuse gastric cancer: assessment of 42 new families and review of genetic screening criteria.
Author: Brooks-Wilson, A R|Kaurah, P|Suriano, G|Leach, S|Senz, J|Grehan, N|Butterfield, Y S N|Jeyes, J|Schinas, J|Bacani, J|Kelsey, M|Ferreira, P|MacGillivray, B|MacLeod, P|Micek, M|Ford, J|Foulkes, W|Australie, K|Greenberg, C|LaPointe, M|Gilpin, C|Nikkel, S|Gilc
PMID: 15235021
Journal: Eur J Cancer. 2004 Aug;40(12):1897-903.
Title: E-Cadherin (CDH1) and p53 rather than SMAD4 and Caspase-10 germline mutations contribute to genetic predisposition in Portuguese gastric cancer patients.
Author: Oliveira, Carla|Ferreira, Paulo|Nabais, Sergio|Campos, Luisa|Ferreira, Ana|Cirnes, Luis|Alves, Catarina Castro|Veiga, Isabel|Fragoso, Maria|Regateiro, Fernando|Dias, Luis Moreira|Moreira, Herculano|Suriano, Gianpaolo|Machado, Jose Carlos|Lopes, Carlos|Cas
PMID: 15288293
Journal: J Pathol. 2004 Sep;204(1):75-83.
Title: Early-onset gastric carcinomas display molecular characteristics distinct from gastric carcinomas occurring at a later age.
Author: Carvalho, Ralph|Milne, Anya N A|van Rees, Bastiaan P|Caspers, Eric|Cirnes, Luis|Figueiredo, Ceu|Offerhaus, G Johan A|Weterman, Marian A J
PMID: 15307140
Journal: Zhonghua Wai Ke Za Zhi. 2004 Aug 7;42(15):914-7.
Title: [Germline E-cadherin gene mutation screening in familial gastric cancer kindreds].
Author: Jiang, Yong|Wan, Yuan-Lian|Wang, Zhen-Jun|Zhao, Bo|Zhu, Jing|Huang, Yan-Ting
PMID: 15363252
Journal: J Hum Genet. 2004;49(11):591-5. Epub 2004 Sep 10.
Title: A TP53-truncating germline mutation (E287X) in a family with characteristics of both hereditary diffuse gastric cancer and Li-Fraumeni syndrome.
Author: Kim, Il-Jin|Kang, Hio Chung|Shin, Yong|Park, Hye-Won|Jang, Sang-Geun|Han, Song-Yee|Lim, Sun-Kyung|Lee, Min Ro|Chang, Hee Jin|Ku, Ja-Lok|Yang, Han-Kwang|Park, Jae-Gahb
PMID: 15368100
Journal: World J Gastroenterol. 2004 Nov 1;10(21):3088-93.
Title: CDH1 germline mutation in hereditary gastric carcinoma.
Author: Wang, Hai-Dan|Ren, Jun|Zhang, Lian
PMID: 15457549
Journal: Clin Cancer Res. 2004 Oct 1;10(19):6456-9.
Title: [18F]Fluoro-2-deoxy-D-glucose positron emission tomography detects gastric carcinoma in an early stage in an asymptomatic E-cadherin mutation carrier.
Author: van Kouwen, Mariette C A|Drenth, Joost P H|Oyen, Wim J G|de Bruin, Joyce H F M|Ligtenberg, Marjolijn J|Bonenkamp, J J Han|van Krieken, J Han J M|Nagengast, Fokko M
PMID: 15475432
Journal: World J Gastroenterol. 2005 Jan 7;11(1):56-60.
Title: E-cadherin gene C-160A promoter polymorphism and risk of non-cardia gastric cancer in a Chinese population.
Author: Lu, Yan|Xu, Yao-Chu|Shen, Jing|Yu, Rong-Bin|Niu, Ju-Yin|Guo, Jian-Tao|Hu, Xu|Shen, Hong-Bing
PMID: 15609397
Journal: Clin Genet. 2005 Jan;67(1):81-6.
Title: A novel STK11 germline mutation in two siblings with Peutz-Jeghers syndrome complicated by primary gastric cancer.
Author: Shinmura, K|Goto, M|Tao, H|Shimizu, S|Otsuki, Y|Kobayashi, H|Ushida, S|Suzuki, K|Tsuneyoshi, T|Sugimura, H
PMID: 15617552
Journal: Hum Pathol. 2005 Jan;36(1):29-35.
Title: E-cadherin expression in sporadic gastric cancer from Mexico: exon 8 and 9 deletions are infrequent events associated with poor survival.
Author: Gamboa-Dominguez, Armando|Dominguez-Fonseca, Claudia|Chavarri-Guerra, Yanin|Vargas, Roberto|Reyes-Gutierrez, Edgardo|Green, Dan|Quintanilla-Martinez, Leticia|Luber, Birgit|Busch, Raymonde|Becker, Karl-Friedrich|Becker, Ingrid|Hofler, Heinz|Fend, Falko
PMID: 15712179
Journal: Virchows Arch. 2005 Feb;446(2):181-4. Epub 2004 Dec 11.
Title: Role of pathology in the identification of hereditary diffuse gastric cancer: report of a Portuguese family.
Author: Oliveira, Carla|Moreira, Herculano|Seruca, Raquel|de Oliveira, Manuel Cardoso|Carneiro, Fatima
PMID: 15735979
Journal: Eur J Surg Oncol. 2005 Apr;31(3):259-64.
Title: CDH1 associated gastric cancer: a report of a family and review of the literature.
Author: Moran, C J|Joyce, M|McAnena, O J
PMID: 15780560
Journal: J Surg Oncol. 2005 Jun 1;90(3):114-33; discussion 133.
Title: Gastric cancer: new genetic developments.
Author: Lynch, Henry T|Grady, William|Suriano, Gianpaolo|Huntsman, David
PMID: 15895459
Journal: Cancer Sci. 2005 Jul;96(7):409-13.
Title: Whole-genome analyses of loss of heterozygosity and methylation analysis of four tumor-suppressor genes in N-methyl-N'-nitro-N-nitrosoguanidine-induced rat stomach carcinomas.
Author: Niwa, Tohru|Yamashita, Satoshi|Tsukamoto, Tetsuya|Kuramoto, Takashi|Nomoto, Tomoko|Wakazono, Kuniko|Fujita, Hirofumi|Matsushima, Taijiro|Tatematsu, Masae|Sugimura, Takashi|Ushijima, Toshikazu
PMID: 16053512
Journal: Clin Cancer Res. 2005 Aug 1;11(15):5401-9.
Title: Characterization of a recurrent germ line mutation of the E-cadherin gene: implications for genetic testing and clinical management.
Author: Suriano, Gianpaolo|Yew, Sandie|Ferreira, Paulo|Senz, Janine|Kaurah, Pardeep|Ford, James M|Longacre, Teri A|Norton, Jeffrey A|Chun, Nicki|Young, Sean|Oliveira, Maria J|Macgillivray, Barbara|Rao, Arundhati|Sears, Dawn|Jackson, Charles E|Boyd, Jeff|Yee, Cind
PMID: 16061854
Journal: Oncol Rep. 2005 Oct;14(4):1083-6.
Title: Comparative genomics on SNAI1, SNAI2, and SNAI3 orthologs.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 16142376
Journal: Rev Med Chil. 2005 Aug;133(8):874-80.
Title: [Promoter methylation profile in gastric cancer].
Author: Roa, Juan Carlos|Anabalon, Leonardo|Roa, Ivan|Tapia, Oscar|Melo, Angelica|Villaseca, Miguel|Araya, Juan Carlos
PMID: 16163424
Journal: Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2005 Oct;22(5):557-9.
Title: [Association of -160(C-->A) polymorphism in CDH1 gene with gastric cancer risk in Fujian Chinese population].
Author: Song, Chuan-gui|Huang, Chang-ming|Liu, Xing|Lu, Hui-shan|Zhang, Xiang-fu|Huang, Wei
PMID: 16215948
Journal: Int J Oncol. 2005 Dec;27(6):1677-83.
Title: Epithelial-mesenchymal transition in gastric cancer (Review).
Author: Katoh, Masaru
PMID: 16273224
Journal: World J Surg Oncol. 2005 Nov 14;3:73.
Title: Aberrant E-cadherin staining patterns in invasive mammary carcinoma.
Author: Harigopal, Malini|Shin, Sandra J|Murray, Melissa P|Tickoo, Satish K|Brogi, Edi|Rosen, Paul Peter
PMID: 16287501
Journal: Cancer. 2006 Mar 15;106(6):1250-9.
Title: Accumulation of DNA methylation is associated with tumor stage in gastric cancer.
Author: Oue, Naohide|Mitani, Yoshitsugu|Motoshita, Junichi|Matsumura, Shunji|Yoshida, Kazuhiro|Kuniyasu, Hiroki|Nakayama, Hirofumi|Yasui, Wataru
PMID: 16475210
Journal: Int J Surg Pathol. 2006 Jan;14(1):21-33.
Title: Genetics, pathology, and clinics of familial gastric cancer.
Author: Oliveira, Carla|Seruca, Raquel|Carneiro, Fatima
PMID: 16501831
Journal: Diagn Mol Pathol. 2006 Mar;15(1):24-9.
Title: CDH1 gene promoter hypermethylation in gastric cancer: relationship to Goseki grading, microsatellite instability status, and EBV invasion.
Author: Zazula, Monika|Ferreira, Ana Maria|Czopek, Jacek P|Kolodziejczyk, Piotr|Sinczak-Kuta, Anna|Klimkowska, Agnieszka|Wojcik, Piotr|Okon, Krzysztof|Bialas, Magdalena|Kulig, Jan|Stachura, Jerzy
PMID: 16531765
Journal: Rev Esp Enferm Dig. 2006 Jan;98(1):36-41.
Title: Single nucleotide polymorphisms (SNPs) at CDH1 promoter region in familial gastric cancer.
Author: Ramos-de la Medina, A|More, H|Medina-Franco, H|Humar, B|Gamboa, A|Ortiz, L J|Donohue, J H|Guilford, P
PMID: 16555931
Journal: Hum Mol Genet. 2006 May 15;15(10):1704-12. Epub 2006 Apr 6.
Title: E-cadherin missense mutations, associated with hereditary diffuse gastric cancer (HDGC) syndrome, display distinct invasive behaviors and genetic interactions with the Wnt and Notch pathways in Drosophila epithelia.
Author: Pereira, Paulo S|Teixeira, Alexandra|Pinho, Sofia|Ferreira, Paulo|Fernandes, Joana|Oliveira, Carla|Seruca, Raquel|Suriano, Gianpaolo|Casares, Fernando
PMID: 16600987
Journal: World J Gastroenterol. 2006 Apr 14;12(14):2168-73.
Title: Mechanisms inactivating the gene for E-cadherin in sporadic gastric carcinomas.
Author: Liu, Yao-Chi|Shen, Chen-Yang|Wu, Hurng-Sheng|Hsieh, Tsai-Yuan|Chan, De-Chuan|Chen, Cheng-Jueng|Yu, Jyh-Cherng|Yu, Cheng-Ping|Harn, Horng-Jyh|Chen, Peng-Jen|Hsieh, Chung-Bao|Chen, Teng-Wei|Hsu, Huan-Mieng
PMID: 16610016
Journal: J Med Genet. 2006 Nov;43(11):867-72. Epub 2006 Jun 26.
Title: CDH1/E-cadherin germline mutations in early-onset gastric cancer.
Author: Bacani, J T|Soares, M|Zwingerman, R|di Nicola, N|Senz, J|Riddell, R|Huntsman, D G|Gallinger, S
PMID: 16801346
Journal: World J Gastroenterol. 2006 Jul 14;12(26):4228-31.
Title: Disordered beta-catenin expression and E-cadherin/CDH1 promoter methylation in gastric carcinoma.
Author: Wang, Li|Zhang, Fan|Wu, Ping-Ping|Jiang, Xu-Cheng|Zheng, Lin|Yu, Ying-Yan
PMID: 16830381
Journal: Eur J Surg Oncol. 2006 Dec;32(10):1110-3. Epub 2006 Jul 25.
Title: A novel mutation in the E-cadherin gene in the first family with hereditary diffuse gastric cancer reported in Spain.
Author: Rodriguez-Sanjuan, J C|Fontalba, A|Mayorga, M|Bordin, M C|Hyland, S J|Trugeda, S|Garcia, R A|Gomez-Fleitas, M|Fernandez, F|Caldas, C|Fernandez-Luna, J L
PMID: 16870389
Journal: Gastroenterol Clin Biol. 2006 Oct;30(10):1205-13.
Title: [Hereditary diffuse gastric cancer].
Author: Sezeur, Alain|Schielke, Astrid|Larue, Lionel|Flejou, Jean-Francois
PMID: 17075480
Journal: Ned Tijdschr Geneeskd. 2006 Nov 4;150(44):2417-20.
Title: [Preventive resection of hereditary diffuse gastric cancer].
Author: Hoogerbrugge, N|Ligtenberg, M J L|Nagengast, F M|Bonenkamp, J J|van Krieken, J H J M
PMID: 17131699
Journal: Eur J Surg Oncol. 2007 May;33(4):448-51. Epub 2006 Nov 28.
Title: Hereditary diffuse gastric cancer and E-cadherin: description of the first germline mutation in an Italian family.
Author: Roviello, F|Corso, G|Pedrazzani, C|Marrelli, D|De Falco, G|Berardi, A|Garosi, L|Suriano, G|Vindigni, C|De Stefano, A|Leoncini, L|Seruca, R|Pinto, E
PMID: 17126523
Journal: Hum Mutat. 2007 Feb;28(2):203.
Title: Identification of seven novel germline mutations in the human E-cadherin (CDH1) gene.
Author: More, H|Humar, B|Weber, W|Ward, R|Christian, A|Lintott, C|Graziano, F|Ruzzo, A-M|Acosta, E|Boman, B|Harlan, M|Ferreira, P|Seruca, R|Suriano, G|Guilford, P
PMID: 17221870
Journal: Curr Mol Med. 2007 Feb;7(1):15-28.
Title: Early onset gastric cancer: on the road to unraveling gastric carcinogenesis.
Author: Milne, Anya N|Sitarz, Robert|Carvalho, Ralph|Carneiro, Fatima|Offerhaus, G Johan A
PMID: 17311530
Journal: Cancer Res. 2007 Mar 15;67(6):2480-9.
Title: Destabilized adhesion in the gastric proliferative zone and c-Src kinase activation mark the development of early diffuse gastric cancer.
Author: Humar, Bostjan|Fukuzawa, Ryuji|Blair, Vanessa|Dunbier, Anita|More, Helen|Charlton, Amanda|Yang, Han Kwang|Kim, Woo Ho|Reeve, Anthony E|Martin, Iain|Guilford, Parry
PMID: 17363565
Journal: Hum Pathol. 2007 Jun;38(6):903-13. Epub 2007 Mar 21.
Title: Molecular analysis of primary gastric cancer, corresponding xenografts, and 2 novel gastric carcinoma cell lines reveals novel alterations in gastric carcinogenesis.
Author: Milne, Anya N A|Sitarz, Robert|Carvalho, Ralph|Polak, Mirjam M|Ligtenberg, Marjolijn|Pauwels, Patrick|Offerhaus, G Johan A|Weterman, Marian A J
PMID: 17376510
Journal: J Gastrointest Surg. 2007 Mar;11(3):314-7. Epub 2007 Mar 2.
Title: Preemptive total gastrectomy for hereditary gastric cancer.
Author: Medina-Franco, Heriberto|Barreto-Zuniga, Rafael|Garcia-Alvarez, Miriam N
PMID: 17458604
Journal: Ann Surg. 2007 Jun;245(6):873-9.
Title: CDH1 truncating mutations in the E-cadherin gene: an indication for total gastrectomy to treat hereditary diffuse gastric cancer.
Author: Norton, Jeffrey A|Ham, Christine M|Van Dam, Jacques|Jeffrey, R Brooke|Longacre, Teri A|Huntsman, David G|Chun, Nicki|Kurian, Allison W|Ford, James M
PMID: 17522512
Journal: JAMA. 2007 Jun 6;297(21):2360-72. Epub 2007 Jun 3.
Title: Founder and recurrent CDH1 mutations in families with hereditary diffuse gastric cancer.
Author: Kaurah, Pardeep|MacMillan, Andree|Boyd, Niki|Senz, Janine|De Luca, Alessandro|Chun, Nicki|Suriano, Gianpaolo|Zaor, Sonya|Van Manen, Lori|Gilpin, Cathy|Nikkel, Sarah|Connolly-Wilson, Mary|Weissman, Scott|Rubinstein, Wendy S|Sebold, Courtney|Greenstein, Rob
PMID: 17545690
Journal: Ann Surg Oncol. 2007 Aug;14(8):2246-9. Epub 2007 Jun 5.
Title: Single nucleotide polymorphisms in the promoter region of the E-cadherin gene in gastric cancer: case-control study in a young Mexican population.
Author: Medina-Franco, Heriberto|Ramos-De la Medina, Antonio|Vizcaino, Gloria|Medina-Franco, Jose Luis
PMID: 17549573
Journal: JSLS. 2007 Jan-Mar;11(1):142-7.
Title: Prophylactic laparoscopic-assisted total gastrectomy for hereditary diffuse gastric cancer.
Author: Francis, Wesley P|Rodrigues, Daniald M|Perez, Nolan E|Lonardo, Fulvio|Weaver, Donald|Webber, John D
PMID: 17651578
Journal: J Med Genet. 2007 Nov;44(11):726-31. Epub 2007 Jul 27.
Title: Germline E-cadherin mutations in familial lobular breast cancer.
Author: Masciari, S|Larsson, N|Senz, J|Boyd, N|Kaurah, P|Kandel, M J|Harris, L N|Pinheiro, H C|Troussard, A|Miron, P|Tung, N|Oliveira, C|Collins, L|Schnitt, S|Garber, J E|Huntsman, D
PMID: 17660459
Journal: Carcinogenesis. 2007 Sep;28(9):2013-8. Epub 2007 Aug 8.
Title: Identification and characterization of a novel germ line p53 mutation in familial gastric cancer in the Japanese population.
Author: Yamada, Hidetaka|Shinmura, Kazuya|Okudela, Koji|Goto, Masanori|Suzuki, Masaya|Kuriki, Ken|Tsuneyoshi, Toshihiro|Sugimura, Haruhiko
PMID: 17690113
Journal: Scand J Gastroenterol. 2007 Dec;42(12):1479-85.
Title: Association between CDH1 haplotypes and gastric cancer risk in a Japanese population.
Author: Yamada, Hidetaka|Shinmura, Kazuya|Ikeda, Shinobu|Tao, Hong|Otani, Tetsuya|Hanaoka, Tomoyuki|Tsuneyoshi, Toshihiro|Tsugane, Shoichiro|Sugimura, Haruhiko
PMID: 17852867
Journal: PLoS One. 2007 Sep 26;2(9):e944.
Title: Constitutive phosphorylation of aurora-a on ser51 induces its stabilization and consequent overexpression in cancer.
Author: Kitajima, Shojiro|Kudo, Yasusei|Ogawa, Ikuko|Tatsuka, Masaaki|Kawai, Hidehiko|Pagano, Michele|Takata, Takashi
PMID: 17895985
Journal: Acta Gastroenterol Latinoam. 2007 Sep;37(3):158-63.
Title: [Hereditary diffuse gastric cancer (HDGC): presentation of a family with a new mutation of the CDH1 gene].
Author: Van Domselaar, Fernando|Correa, Daniel|Vaccaro, Carlos|Redal, Maria|Van Domselaar, Reinaldo|Huntsman, David|Kaurah, Pardeep|Senz, Janine|Lynch, Henry
PMID: 17955726
Journal: Genet Med. 2007 Nov;9(11):752-60.
Title: Identification of an intronic single nucleotide polymorphism leading to allele dropout during validation of a CDH1 sequencing assay: implications for designing polymerase chain reaction-based assays.
Author: Mullins, Franklin M|Dietz, Lisa|Lay, Marla|Zehnder, James L|Ford, James|Chun, Nicolette|Schrijver, Iris
PMID: 18007144
Journal: Hered Cancer Clin Pract. 2007 Dec 15;5(4):183-94.
Title: A short guide to hereditary diffuse gastric cancer.
Author: Guilford, Parry|Blair, Vanessa|More, Helen|Humar, Bostjan
PMID: 19725995
Journal: J Clin Pathol. 2008 Jan;61(1):25-30. Epub 2007 May 18.
Title: Molecular pathology of familial gastric cancer, with an emphasis on hereditary diffuse gastric cancer.
Author: Carneiro, F|Oliveira, C|Suriano, G|Seruca, R
PMID: 17513507
Journal: Ann Oncol. 2008 Mar;19(3):516-9. Epub 2007 Nov 6.
Title: Endogastric capsule for E-cadherin gene (CDH1) promoter hypermethylation assessment in DNA from gastric juice of diffuse gastric cancer patients.
Author: Muretto, P|Ruzzo, A|Pizzagalli, F|Graziano, F|Maltese, P|Zingaretti, C|Berselli, E|Donnarumma, N|Magnani, M
PMID: 17986624
Journal: Fam Cancer. 2008;7(1):73-82.
Title: Hereditary diffuse gastric cancer: association with lobular breast cancer.
Author: Schrader, Kasmintan A|Masciari, Serena|Boyd, Niki|Wiyrick, Sara|Kaurah, Pardeep|Senz, Janine|Burke, Wylie|Lynch, Henry T|Garber, Judy E|Huntsman, David G
PMID: 18046629
Journal: J Surg Oncol. 2008 Mar 1;97(3):294-6.
Title: No mucosal escape of signet-ring cell carcinoma for ten years in a patient with familial aggregation of gastric cancer.
Author: Tanis, Pieter J|Ten Kate, Fiebo J W|van Lanschot, J Jan B
PMID: 18161866
Journal: Helicobacter. 2008 Feb;13(1):35-41.
Title: CpG island hypermethylation of tumor-suppressor genes in H. pylori-infected non-neoplastic gastric mucosa is linked with gastric cancer risk.
Author: Kaise, Mitsuru|Yamasaki, Takuji|Yonezawa, Jin|Miwa, Jun|Ohta, Yasuhiko|Tajiri, Hisao
PMID: 18205664
Journal: Am J Surg Pathol. 2008 Jun;32(6):799-809.
Title: Risk-reducing total gastrectomy for germline mutations in E-cadherin (CDH1): pathologic findings with clinical implications.
Author: Rogers, William M|Dobo, Erika|Norton, Jeffrey A|Van Dam, Jacques|Jeffrey, R Brooke|Huntsman, David G|Kingham, Kerry|Chun, Nicki|Ford, James M|Longacre, Teri A
PMID: 18391748
Journal: Gan To Kagaku Ryoho. 2008 Apr;35(4):551-6.
Title: [Familial aggregation of gastric cancer].
Author: Sugimura, Haruhiko
PMID: 18408421
Journal: Oncogene. 2008 Jul 10;27(30):4255-60.
Title: The NMD mRNA surveillance pathway downregulates aberrant E-cadherin transcripts in gastric cancer cells and in CDH1 mutation carriers.
Author: Karam, R|Carvalho, J|Bruno, I|Graziadio, C|Senz, J|Huntsman, D|Carneiro, F|Seruca, R|Wilkinson, M F|Oliveira, C
PMID: 18427545
Journal: Cancer. 2008 Jun 15;112(12):2655-63.
Title: Hereditary diffuse gastric cancer: diagnosis, genetic counseling, and prophylactic total gastrectomy.
Author: Lynch, Henry T|Kaurah, Pardeep|Wirtzfeld, Debrah|Rubinstein, Wendy S|Weissman, Scott|Lynch, Jane F|Grady, William|Wiyrick, Sara|Senz, Janine|Huntsman, David G
PMID: 18442100
Journal: BMC Cancer. 2008 May 15;8:138.
Title: A novel diffuse gastric cancer susceptibility variant in E-cadherin (CDH1) intron 2: a case control study in an Italian population.
Author: Nasri, Soroush|More, Helen|Graziano, Francesco|Ruzzo, Annamaria|Wilson, Emily|Dunbier, Anita|McKinney, Cushla|Merriman, Tony|Guilford, Parry|Magnani, Mauro|Humar, Bostjan
PMID: 18482459
Journal: Aliment Pharmacol Ther. 2008 Sep 1;28(5):565-73.
Title: Meta-analysis: tumour invasion-related genetic polymorphisms and gastric cancer susceptibility.
Author: Gao, L|Nieters, A|Brenner, H
PMID: 18544073
Journal: Exp Oncol. 2008 Jun;30(2):112-6.
Title: Promoter methylation of cancer-related genes in gastric carcinoma.
Author: Poplawski, T|Tomaszewska, K|Galicki, M|Morawiec, Z|Blasiak, J
PMID: 18566573
Journal: Transl Oncol. 2008 Mar;1(1):28-35.
Title: Increased frequency of CpG island methylator phenotype and CDH1 methylation in a gastric cancer high-risk region of china.
Author: Zhang, Kai-Li|Sun, Yuan|Li, Yan|Liu, Ming|Qu, Bo|Cui, Shu-Hong|Kong, Qing-You|Chen, Xiao-Yan|Li, Hong|Liu, Jia
PMID: 18607505
Journal: Rev Med Chil. 2008 Apr;136(4):451-8.
Title: [Gene methylation patterns in digestive tumors].
Author: Roa S, Juan Carlos|Garcia M, Patricia|Melo A, Angelica|Tapia E, Oscar|Villaseca H, Miguel|Araya O, Juan Carlos|Guzman G, Pablo
PMID: 18769787
Journal: J Pathol. 2008 Nov;216(3):295-306.
Title: Mechanisms and sequelae of E-cadherin silencing in hereditary diffuse gastric cancer.
Author: Barber, M|Murrell, A|Ito, Y|Maia, A-T|Hyland, S|Oliveira, C|Save, V|Carneiro, F|Paterson, A L|Grehan, N|Dwerryhouse, S|Lao-Sirieix, P|Caldas, C|Fitzgerald, R C
PMID: 18788075
Journal: Cancer. 2008 Oct 1;113(7 Suppl):1850-6.
Title: Hereditary diffuse gastric cancer: implications of genetic testing for screening and prophylactic surgery.
Author: Cisco, Robin M|Ford, James M|Norton, Jeffrey A
PMID: 18798546
Journal: Cancer Epidemiol Biomarkers Prev. 2008 Oct;17(10):2555-64.
Title: LINE-1 hypomethylation is associated with increased CpG island methylation in Helicobacter pylori-related enlarged-fold gastritis.
Author: Yamamoto, Eiichiro|Toyota, Minoru|Suzuki, Hiromu|Kondo, Yutaka|Sanomura, Tamana|Murayama, Yoko|Ohe-Toyota, Mutsumi|Maruyama, Reo|Nojima, Masanori|Ashida, Masami|Fujii, Kyoko|Sasaki, Yasushi|Hayashi, Norio|Mori, Mitsuru|Imai, Kohzoh|Tokino, Takashi|Shinomu
PMID: 18842996
Journal: Rev Med Chir Soc Med Nat Iasi. 2008 Apr-Jun;112(2):432-6.
Title: Correlation between E-cadherin abnormal expressions in different types of cancer and the process of metastasis.
Author: Margineanu, Eliana|Cotrutz, Carmen Elena|Cotrutz, C
PMID: 19295016
Journal: Birth Defects Res A Clin Mol Teratol. 2009 Feb;85(2):169-73.
Title: AXIN2 and CDH1 polymorphisms, tooth agenesis, and oral clefts.
Author: Letra, Ariadne|Menezes, Renato|Granjeiro, Jose M|Vieira, Alexandre R
PMID: 18683894
Journal: Eur J Cancer Prev. 2009 Feb;18(1):46-9.
Title: CDH1 C-160A promoter polymorphism and gastric cancer risk.
Author: Corso, Giovanni|Berardi, Anna|Marrelli, Daniele|Pedrazzani, Corrado|Garosi, Lorenzo|Pinto, Enrico|Roviello, Franco
PMID: 19077564
Journal: Hum Mol Genet. 2009 May 1;18(9):1545-55.
Title: Germline CDH1 deletions in hereditary diffuse gastric cancer families.
Author: Oliveira, Carla|Senz, Janine|Kaurah, Pardeep|Pinheiro, Hugo|Sanges, Remo|Haegert, Anne|Corso, Giovanni|Schouten, Jan|Fitzgerald, Rebecca|Vogelsang, Holger|Keller, Gisela|Dwerryhouse, Sarah|Grimmer, Donna|Chin, Suet-Feung|Yang, Han-Kwang|Jackson, Charles E
PMID: 19168852
Journal: Cancer Res. 2009 Mar 1;69(5):2050-6.
Title: E-cadherin deficiency initiates gastric signet-ring cell carcinoma in mice and man.
Author: Humar, Bostjan|Blair, Vanessa|Charlton, Amanda|More, Helen|Martin, Iain|Guilford, Parry
PMID: 19223545
Journal: Hum Genet. 2009 Apr;125(3):337.
Title: Novel human pathological mutations. Gene symbol: CDH1. Disease: gastric cancer.
Author: Ghaffari, Saeed Reza|Dastan, Jila|Rafati, Maryam|Sabokbar, Tayebeh
PMID: 19309801
Journal: Oncol Rep. 2009 May;21(5):1251-9.
Title: Comparative analysis of DNA methylation between primary and metastatic gastric carcinoma.
Author: Kim, Ji Hun|Jung, Eun Ji|Lee, Hye Seung|Kim, Min A|Kim, Woo Ho
PMID: 19360301
Journal: Eur J Cancer. 2009 Sep;45(14):2562-8.
Title: Meta-analysis of genetic polymorphisms and gastric cancer risk: variability in associations according to race.
Author: Loh, Marie|Koh, King Xin|Yeo, Boon Huat|Song, Chun Meng|Chia, Kee Seng|Zhu, Feng|Yeoh, Khay Guan|Hill, Jeffrey|Iacopetta, Barry|Soong, Richie
PMID: 19375306
Journal: Ann Surg Oncol. 2009 Jul;16(7):1890-5.
Title: Prophylactic total gastrectomy (PTG) for hereditary diffuse gastric cancer (HDGC): the Newfoundland experience with 23 patients.
Author: Hebbard, P C|Macmillan, A|Huntsman, D|Kaurah, P|Carneiro, F|Wen, X|Kwan, A|Boone, D|Bursey, F|Green, J|Fernandez, B|Fontaine, D|Wirtzfeld, D A
PMID: 19408054
Journal: Best Pract Res Clin Gastroenterol. 2009;23(2):147-57.
Title: Hereditary gastric cancer.
Author: Oliveira, Carla|Seruca, Raquel|Carneiro, Fatima
PMID: 19414142
Journal: Int J Oncol. 2009 Jun;34(6):1737-42.
Title: Integrative genomic analyses of ZEB2: Transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1alpha, POU/OCT, and NF-kappaB.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 19424592
Journal: Cancer Sci. 2009 Jul;100(7):1192-7.
Title: Chronic nonsteroidal anti-inflammatory drug (NSAID) use suppresses multiple CpG islands hyper methylation (CIHM) of tumor suppressor genes in the human gastric mucosa.
Author: Tahara, Tomomitsu|Shibata, Tomoyuki|Yamashita, Hiromi|Nakamura, Masakatsu|Yoshioka, Daisuke|Okubo, Masaaki|Hirata, Ichiro|Arisawa, Tomiyasu
PMID: 19432886
Journal: Mol Cancer. 2009 Aug 12;8:63.
Title: Absence of germline mono-allelic promoter hypermethylation of the CDH1 gene in gastric cancer patients.
Author: Yamada, Hidetaka|Shinmura, Kazuya|Goto, Masanori|Iwaizumi, Moriya|Konno, Hiroyuki|Kataoka, Hideki|Yamada, Masami|Ozawa, Takachika|Tsuneyoshi, Toshihiro|Tanioka, Fumihiko|Sugimura, Haruhiko
PMID: 19671196
Journal: Int J Mol Med. 2009 Oct;24(4):563-9.
Title: Effect of polymorphisms of IL-17A, -17F and MIF genes on CpG island hyper-methylation (CIHM) in the human gastric mucosa.
Author: Tahara, Tomomitsu|Shibata, Tomoyuki|Nakamura, Masakatsu|Yamashita, Hiromi|Yoshioka, Daisuke|Okubo, Masaaki|Yonemura, Joh|Maeda, Yoshiteru|Maruyama, Naoko|Kamano, Toshiaki|Kamiya, Yoshio|Fujita, Hiroshi|Nakagawa, Yoshihito|Nagasaka, Mitsuo|Iwata, Masami|Hi
PMID: 19724898
Journal: Zhonghua Wai Ke Za Zhi. 2009 Aug 15;47(16):1204-8.
Title: [Associations of E-cadherin gene (CDH1) and hereditary gastric cancer in China].
Author: Song, Wu|He, Yu-long|Zhang, Chang-hua|Cai, Shi-rong|Zhou, Xue-fu|Peng, Jian-jun|Wang, Zhao|Yang, Dong-jie|Zhan, Wen-hua
PMID: 19781162
Journal: Rev Gastroenterol Mex. 2009;74(3):256-8.
Title: [Hereditary non-polyposis colorectal cancer associated with hereditary gastric cancer. A case report.].
Author: Castaneda-Argaiz, R|Gonzalez-Contreras, Q H|Medina-Franco, H|Rodriguez-Zentner, H A|Tapia-Cid de Leon, H|Vergara-Fernandez, O
PMID: 19858019
Journal: Dig Dis Sci. 2010 Jan;55(1):54-9.
Title: Chronic aspirin use suppresses CDH1 methylation in human gastric mucosa.
Author: Tahara, Tomomitsu|Shibata, Tomoyuki|Nakamura, Masakatsu|Yamashita, Hiromi|Yoshioka, Daisuke|Okubo, Masaaki|Maruyama, Naoko|Kamano, Toshiaki|Kamiya, Yoshio|Fujita, Hiroshi|Nagasaka, Mitsuo|Iwata, Masami|Takahama, Kazuya|Watanabe, Makoto|Hirata, Ichiro|Aris
PMID: 19184424
Journal: Eur J Gastroenterol Hepatol. 2010 Mar;22(3):306-10.
Title: Germline mutation of the E-cadherin gene in three sibling cases with advanced gastric cancer: clinical consequences for the other family members.
Author: Mayrbaeurl, Beate|Keller, Gisela|Schauer, Walter|Burgstaller, Sonja|Czompo, Manfred|Hoebling, Walter|Knoflach, Peter|Duba, Hans C|Hoefler, Heinz|Thaler, Josef
PMID: 19474748
Journal: Hum Mol Genet. 2010 Mar 1;19(5):943-52.
Title: Allele-specific CDH1 downregulation and hereditary diffuse gastric cancer.
Author: Pinheiro, Hugo|Bordeira-Carrico, Renata|Seixas, Susana|Carvalho, Joana|Senz, Janine|Oliveira, Patricia|Inacio, Patricia|Gusmao, Leonor|Rocha, Jorge|Huntsman, David|Seruca, Raquel|Oliveira, Carla
PMID: 19965908
Journal: Int J Mol Med. 2010 Mar;25(3):471-7.
Title: Association between IL-17A, -17F and MIF polymorphisms predispose to CpG island hyper-methylation in gastric cancer.
Author: Tahara, Tomomitsu|Shibata, Tomoyuki|Nakamura, Masakatsu|Yamashita, Hiromi|Yoshioka, Daisuke|Okubo, Masaaki|Yonemura, Joh|Maeda, Yoshiteru|Maruyama, Naoko|Kamano, Toshiaki|Kamiya, Yoshio|Fujita, Hiroshi|Nakagawa, Yoshihito|Nagasaka, Mitsuo|Iwata, Masami|Hi
PMID: 20127054
Journal: Anticancer Res. 2010 Jan;30(1):239-44.
Title: CpG island promoter methylation (CIHM) status of tumor suppressor genes correlates with morphological appearances of gastric cancer.
Author: Tahara, Tomomitsu|Shibata, Tomoyuki|Arisawa, Tomiyasu|Nakamura, Masakatsu|Yamashita, Hiromi|Yoshioka, Daisuke|Okubo, Masaaki|Yonemura, Joh|Maeda, Yoshiteru|Maruyama, Naoko|Kamano, Toshiaki|Kamiya, Yoshio|Fujita, Hiroshi|Nakagawa, Yoshihito|Nagasaka, Mitsu
PMID: 20150642
Journal: Dig Dis Sci. 2010 Dec;55(12):3449-57.
Title: Association between cyclin D1 polymorphism with CpG island promoter methylation status of tumor suppressor genes in gastric cancer.
Author: Tahara, Tomomitsu|Shibata, Tomoyuki|Nakamura, Masakatsu|Yamashita, Hiromi|Yoshioka, Daisuke|Okubo, Masaaki|Yonemura, Joh|Maeda, Yoshiteru|Maruyama, Naoko|Kamano, Toshiaki|Kamiya, Yoshio|Fujita, Hiroshi|Nakagawa, Yoshihito|Nagasaka, Mitsuo|Iwata, Masami|Hi
PMID: 20397048
Journal: Cancer Treat Res. 2010;155:33-63.
Title: Hereditary diffuse gastric cancer.
Author: Schrader, Kasmintan|Huntsman, David
PMID: 20517687
Journal: Arq Gastroenterol. 2010 Jan-Mar;47(1):7-12.
Title: Methylation status of CDH1 gene in samples of gastric mucous from Brazilian patients with chronic gastritis infected by Helicobacter pylori.
Author: Kague, Erika|Thomazini, Cristiane Melissa|Pardini, Maria Ines de Campo Moura|Carvalho, Fabricio de|Leite, Celso Vieira|Pinheiro, Nidia Alice
PMID: 20520968
Journal: Am J Surg Pathol. 2010 Jul;34(7):1007-13.
Title: Periodic acid-schiff is superior to hematoxylin and eosin for screening prophylactic gastrectomies from CDH1 mutation carriers.
Author: Lee, Anna F|Rees, Henrike|Owen, David A|Huntsman, David G
PMID: 20534996
Journal: J Med Genet. 2010 Jul;47(7):436-44.
Title: Hereditary diffuse gastric cancer: updated consensus guidelines for clinical management and directions for future research.
Author: Fitzgerald, Rebecca C|Hardwick, Richard|Huntsman, David|Carneiro, Fatima|Guilford, Parry|Blair, Vanessa|Chung, Daniel C|Norton, Jeff|Ragunath, Krishnadath|Van Krieken, J Han|Dwerryhouse, Sarah|Caldas, Carlos
PMID: 20591882
Journal: World J Gastroenterol. 2010 Jul 21;16(27):3432-6.
Title: Association of E-cadherin (CDH1) gene polymorphisms and gastric cancer risk.
Author: Al-Moundhri, Mansour S|Al-Khanbashi, Manal|Al-Kindi, Mohammed|Al-Nabhani, Maryam|Burney, Ikram A|Al-Farsi, Abdulaziz|Al-Bahrani, Bassim
PMID: 20632448
Journal: Anticancer Res. 2010 Jun;30(6):2209-16.
Title: CXCR4, a potential predictive marker for docetaxel sensitivity in gastric cancer.
Author: Xie, Li|Wei, Jia|Qian, Xiaoping|Chen, Gang|Yu, Lixia|Ding, Yitao|Liu, Baorui
PMID: 20651371
Journal: Anticancer Res. 2010 Jun;30(6):2225-33.
Title: Promoter polymorphisms and methylation of E-cadherin (CDH1) and KIT in gastric cancer patients from northern Brazil.
Author: Borges, Barbara do Nascimento|Santos, Erivelton da Silva|Bastos, Carlos Eduardo Matos Carvalho|Pinto, Laine Celestino|Anselmo, Nilson Praia|Quaresma, Juarez Antonio Simoes|Calcagno, Danielle Queiroz|Burbano, Rommel Mario Rodriguez|Harada, Maria Lucia
PMID: 20651373
Journal: Pathologe. 2010 Oct;31(6):423-9.
Title: [Hereditary gastric cancer].
Author: Wolf, E-M|Geigl, J B|Svrcek, M|Vieth, M|Langner, C
PMID: 20824432
Journal: Lab Invest. 2010 Nov;90(11):1604-14.
Title: De novo expression of CD44 variants in sporadic and hereditary gastric cancer.
Author: da Cunha, Cristiana Branco|Oliveira, Carla|Wen, Xiaogang|Gomes, Barbara|Sousa, Sonia|Suriano, Gianpaolo|Grellier, Maritie|Huntsman, David G|Carneiro, Fatima|Granja, Pedro L|Seruca, Raquel
PMID: 20856229
Journal: PLoS One. 2010 Dec 23;5(12):e15585.
Title: The prognostic significance of whole blood global and specific DNA methylation levels in gastric adenocarcinoma.
Author: Al-Moundhri, Mansour S|Al-Nabhani, Maryam|Tarantini, Letizia|Baccarelli, Andrea|Rusiecki, Jennifer A
PMID: 21203466
Journal: JSLS. 2010 Jul-Sep;14(3):348-52.
Title: Prophylactic laparoscopic gastrectomy for hereditary diffuse gastric cancer: a case series in a single family.
Author: Hackenson, David|Edelman, David A|McGuire, Tim|Weaver, Donald W|Webber, John D
PMID: 21333186
Journal: Exp Ther Med. 2010 Nov;1(6):1035-1040.
Title: Association between common genetic variants in pre-microRNAs and the clinicopathological characteristics and survival of gastric cancer patients.
Author: Okubo, Masaaki|Tahara, Tomomitsu|Shibata, Tomoyuki|Yamashita, Hiromi|Nakamura, Masakatsu|Yoshioka, Daisuke|Yonemura, Joh|Kamiya, Yoshio|Ishizuka, Takamitsu|Nakagawa, Yoshihito|Nagasaka, Mitsuo|Iwata, Masami|Arisawa, Tomiyasu|Hirata, Ichiro
PMID: 22993637
Journal: Int J Cancer. 2011 Apr 1;128(7):1606-13.
Title: MSI phenotype and MMR alterations in familial and sporadic gastric cancer.
Author: Leite, Marina|Corso, Giovanni|Sousa, Sonia|Milanezi, Fernanda|Afonso, Luis P|Henrique, Rui|Soares, Jose Manuel|Castedo, Sergio|Carneiro, Fatima|Roviello, Franco|Oliveira, Carla|Seruca, Raquel
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Journal: Surgery. 2011 Mar;149(3):347-55.
Title: Prophylactic total gastrectomy for individuals with germline CDH1 mutation.
Author: Pandalai, Prakash K|Lauwers, Greg Y|Chung, Daniel C|Patel, Devanshi|Yoon, Sam S
PMID: 20719348
Journal: Pharmacogenomics J. 2011 Apr;11(2):81-92.
Title: Trastuzumab and beyond: sequencing cancer genomes and predicting molecular networks.
Author: Roukos, D H
PMID: 20975737
Journal: Fam Cancer. 2011 Jun;10(2):391-6.
Title: Familial gastric cancer: update for practice management.
Author: Corso, Giovanni|Marrelli, Daniele|Roviello, Franco
PMID: 21184285
Journal: DNA Cell Biol. 2011 Jun;30(6):395-400.
Title: The E-cadherin (CDH1) -160C>A polymorphism associated with gastric cancer among Asians but not Europeans.
Author: Wang, Qiong|Gu, Dongying|Wang, Meilin|Zhang, Zhengdong|Tang, Jinhai|Chen, Jinfei
PMID: 21214416
Journal: Cancer. 2011 Jul 15;117(14):3112-7.
Title: Germline mutations of the E-cadherin gene in families with inherited invasive lobular breast carcinoma but no diffuse gastric cancer.
Author: Xie, Ze Ming|Li, Lai Sheng|Laquet, Claire|Penault-Llorca, Frederique|Uhrhammer, Nancy|Xie, Xiao Ming|Bignon, Yves Jean
PMID: 21271559
Journal: Digestion. 2011;83(4):241-9.
Title: Role of DNA methylation in the development of diffuse-type gastric cancer.
Author: Yamamoto, Eiichiro|Suzuki, Hiromu|Takamaru, Hiroyuki|Yamamoto, Hiroyuki|Toyota, Minoru|Shinomura, Yasuhisa
PMID: 21273772
Journal: J Surg Oncol. 2011 Jun 1;103(7):687-94.
Title: Hypermethylation of tumor-related genes in Tunisian patients with gastric carcinoma: clinical and biological significance.
Author: Ben Ayed-Guerfali, Dorra|Benhaj, Khemais|Khabir, Abdelmajid|Abid, Mohamed|Bayrouti, Mohamed Issam|Sellami-Boudawara, Tahia|Gargouri, Ali|Mokdad-Gargouri, Raja
PMID: 21308683
Journal: Ned Tijdschr Geneeskd. 2011;155:A2731.
Title: [Familial gastric cancer: diagnosis, treatment and periodic surveillance].
Author: Kluijt, Irma|Sijmons, Rolf H|Hoogerbrugge, Nicoline|Vasen, Hans F A|Cats, Anemieke
PMID: 21329544
Journal: Patholog Res Int. 2011 Feb 6;2011:845821.
Title: Hereditary diffuse gastric cancer: multidisciplinary case report with review of the literature.
Author: Wilcox, Rebecca|Perpich, Melody|Noffsinger, Amy|Posner, Mitchell C|Cooper, Kumarasen
PMID: 21331337
Journal: DNA Cell Biol. 2011 Nov;30(11):937-45.
Title: A meta-analysis of CDH1 C-160A genetic polymorphism and gastric cancer risk.
Author: Cui, Yun|Xue, Huiping|Lin, Bing|Ni, Peihua|Fang, Jing-Yuan
PMID: 21612411
Journal: Ann Surg Oncol. 2011 Dec;18 Suppl 3:S192-3.
Title: Preventive and therapeutic implications of positive CDH1 testing in diffuse gastric cancer.
Author: Hottenrott, Christof
PMID: 21761101
Journal: Cancer Sci. 2011 Oct;102(10):1782-8.
Title: Germline alterations in the CDH1 gene in familial gastric cancer in the Japanese population.
Author: Yamada, Hidetaka|Shinmura, Kazuya|Ito, Hiroaki|Kasami, Masako|Sasaki, Naomi|Shima, Hideyuki|Ikeda, Masami|Tao, Hong|Goto, Masanori|Ozawa, Takachika|Tsuneyoshi, Toshihiro|Tanioka, Fumihiko|Sugimura, Haruhiko
PMID: 21777349
Journal: Cancer Lett. 2011 Dec 1;311(1):85-95.
Title: Aberrant DNA methylation of cancer-associated genes in gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST).
Author: Balassiano, Karen|Lima, Sheila|Jenab, Mazda|Overvad, Kim|Tjonneland, Anne|Boutron-Ruault, Marie Christine|Clavel-Chapelon, Francoise|Canzian, Federico|Kaaks, Rudolf|Boeing, Heiner|Meidtner, Karina|Trichopoulou, Antonia|Laglou, Pagona|Vineis, Paolo|Panico,
PMID: 21831520
Journal: Palliat Support Care. 2011 Sep;9(3):305-13.
Title: How do you live without a stomach?: a multiple case study examination of total gastrectomy for palliation or prophylaxis.
Author: Garland, Sheila N|Lounsberry, Joshua|Pelletier, Guy|Bathe, Oliver F
PMID: 21838951
Journal: Pathobiology. 2011;78(6):302-10.
Title: Molecular pathology of gastric carcinoma.
Author: Jang, Bo-Gun|Kim, Woo Ho
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Journal: BMB Rep. 2011 Nov;44(11):725-9.
Title: Novel mechanism of a CDH1 splicing mutation in a Korean patient with signet ring cell carcinoma.
Author: Kim, Sollip|Ki, Chang Seok|Kim, Kyoung-Mee|Lee, Myoung-Gun|Kim, Sehwa|Bae, Jae-Moon|Kim, Jong-Won
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Journal: Epigenomics. 2011 Aug;3(4):417-29.
Title: Global DNA methylation and tumor suppressor gene promoter methylation and gastric cancer risk in an Omani Arab population.
Author: Rusiecki, Jennifer A|Al-Nabhani, Maryam|Tarantini, Letizia|Chen, Ligong|Baccarelli, Andrea|Al-Moundhri, Mansour S
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Journal: BMC Cancer. 2011 Dec 7;11:509.
Title: Biomarker analysis of cetuximab plus oxaliplatin/leucovorin/5-fluorouracil in first-line metastatic gastric and oesophago-gastric junction cancer: results from a phase II trial of the Arbeitsgemeinschaft Internistische Onkologie (AIO).
Author: Luber, Birgit|Deplazes, Joelle|Keller, Gisela|Walch, Axel|Rauser, Sandra|Eichmann, Martin|Langer, Rupert|Hofler, Heinz|Hegewisch-Becker, Susanna|Folprecht, Gunnar|Woll, Ewald|Decker, Thomas|Endlicher, Esther|Lorenzen, Sylvie|Fend, Falko|Peschel, Christian
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Journal: Mol Biol Rep. 2012 Feb;39(2):1283-6.
Title: CDH1 promoter polymorphism and stomach cancer susceptibility.
Author: Li, Yi-Ling|Tian, Zhong|Zhang, Jian-Bing|Fu, Bao-Yu
PMID: 21625863
Journal: Clin Genet. 2012 Sep;82(3):283-7.
Title: De novo CDH1 mutation in a family presenting with early-onset diffuse gastric cancer.
Author: Shah, M A|Salo-Mullen, E|Stadler, Z|Ruggeri, J M|Mirander, M|Pristyazhnyuk, Y|Zhang, L
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Journal: Gut. 2012 Mar;61(3):344-53.
Title: Synergistic tumour suppressor activity of E-cadherin and p53 in a conditional mouse model for metastatic diffuse-type gastric cancer.
Author: Shimada, Shu|Mimata, Ayako|Sekine, Masaki|Mogushi, Kaoru|Akiyama, Yoshimitsu|Fukamachi, Hiroshi|Jonkers, Jos|Tanaka, Hiroshi|Eishi, Yoshinobu|Yuasa, Yasuhito
PMID: 21865403
Journal: Hum Pathol. 2012 Mar;43(3):457-61.
Title: Pancreatic ductal adenocarcinoma in hereditary diffuse gastric cancer. A case report.
Author: Ottenhof, Niki A|de Wilde, Roeland F|Morsink, Folkert H M|de Leng, Wendy W J|Ausems, Margreet G E M|Morreau, Hans|van Hillegersberg, Richard|Offerhaus, G Johan A|Milne, Anya N
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Journal: Int J Cancer. 2012 Jul 15;131(2):367-76.
Title: CDH1-related hereditary diffuse gastric cancer syndrome: clinical variations and implications for counseling.
Author: Kluijt, Irma|Siemerink, Ester J M|Ausems, Margreet G E M|van Os, Theo A M|de Jong, Daphne|Simoes-Correia, Joana|van Krieken, J Han|Ligtenberg, Marjolijn J|Figueiredo, Joana|van Riel, Els|Sijmons, Rolf H|Plukker, John T M|van Hillegersberg, Richard|Dekker,
PMID: 22020549
Journal: Cancer Sci. 2012 Feb;103(2):221-7.
Title: Integrated analysis of whole genome exon array and array-comparative genomic hybridization in gastric and colorectal cancer cells.
Author: Furuta, Kazuyuki|Arao, Tokuzo|Sakai, Kazuko|Kimura, Hideharu|Nagai, Tomoyuki|Tamura, Daisuke|Aomatsu, Keiichi|Kudo, Kanae|Kaneda, Hiroyasu|Fujita, Yoshihiko|Matsumoto, Kazuko|Yamada, Yasuhide|Yanagihara, Kazuyoshi|Sekijima, Masaru|Nishio, Kazuto
PMID: 22034905
Journal: BMC Cancer. 2012 Jan 6;12:8.
Title: Frequency of CDH1 germline mutations in gastric carcinoma coming from high- and low-risk areas: metanalysis and systematic review of the literature.
Author: Corso, Giovanni|Marrelli, Daniele|Pascale, Valeria|Vindigni, Carla|Roviello, Franco
PMID: 22225527
Journal: World J Gastroenterol. 2012 Jan 7;18(1):70-8.
Title: Germline promoter hypermethylation of tumor suppressor genes in gastric cancer.
Author: Wu, Pu-Yuan|Zhang, Zheng|Wang, Jing-Mei|Guo, Wen-Wen|Xiao, Nong|He, Qiong|Wang, Ya-Ping|Fan, Yi-Mei
PMID: 22228973
Journal: J Cancer Res Clin Oncol. 2012 May;138(5):843-58.
Title: Relevance of MET activation and genetic alterations of KRAS and E-cadherin for cetuximab sensitivity of gastric cancer cell lines.
Author: Heindl, Stefan|Eggenstein, Evelyn|Keller, Simone|Kneissl, Julia|Keller, Gisela|Mutze, Kathrin|Rauser, Sandra|Gasteiger, Georg|Drexler, Ingo|Hapfelmeier, Alexander|Hofler, Heinz|Luber, Birgit
PMID: 22290393
Journal: Fam Cancer. 2012 Sep;11(3):363-9.
Title: Familial gastric cancer: guidelines for diagnosis, treatment and periodic surveillance.
Author: Kluijt, Irma|Sijmons, Rolf H|Hoogerbrugge, Nicoline|Plukker, John T|de Jong, Daphne|van Krieken, J Han|van Hillegersberg, Richard|Ligtenberg, Marjolijn|Bleiker, Eveline|Cats, Anemieke
PMID: 22388873
Journal: J Pathol. 2012 Sep;228(1):31-44.
Title: Lack of microRNA-101 causes E-cadherin functional deregulation through EZH2 up-regulation in intestinal gastric cancer.
Author: Carvalho, Joana|van Grieken, Nicole C|Pereira, Patricia M|Sousa, Sonia|Tijssen, Marianne|Buffart, Tineke E|Diosdado, Begona|Grabsch, Heike|Santos, Manuel A S|Meijer, Gerrit|Seruca, Raquel|Carvalho, Beatriz|Oliveira, Carla
PMID: 22450781
Journal: J Surg Oncol. 2012 Nov;106(6):765-71.
Title: CDH1 methylation in preoperative peritoneal washes is an independent prognostic factor for gastric cancer.
Author: Yu, Qi-Ming|Wang, Xin-Bao|Luo, Jun|Wang, Shi|Fang, Xian-Hua|Yu, Jiang-Liu|Ling, Zhi-Qiang
PMID: 22514028
Journal: Mol Biol Rep. 2012 Aug;39(8):8107-13.
Title: CDH1 gene polymorphisms, plasma CDH1 levels and risk of gastric cancer in a Chinese population.
Author: Zhan, Zhen|Wu, Juan|Zhang, Jun-Feng|Yang, Ya-Ping|Tong, Shujuan|Zhang, Chun-Bing|Li, Jin|Yang, Xue-Wen|Dong, Wei
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Journal: Cytokine. 2012 Jul;59(1):20-1.
Title: CDH1 -160C>A gene polymorphism is an ethnicity-dependent risk factor for gastric cancer.
Author: Pan, Feng|Tian, Jing|Zhang, Ying|Pan, Yue-Yin
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Journal: Ann Ital Chir. 2012 May-Jun;83(3):172-6.
Title: Gastric cancer carcinogenesis and tumor progression.
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Journal: Ann Ital Chir. 2012 May-Jun;83(3):177-82.
Title: Familial gastric cancer and germline mutations of E-cadherin.
Author: Corso, Giovanni|Marrelli, Daniele|Roviello, Franco
PMID: 22595728
Journal: Hum Mol Genet. 2012 Oct 1;21(19):4253-69.
Title: Transcription initiation arising from E-cadherin/CDH1 intron2: a novel protein isoform that increases gastric cancer cell invasion and angiogenesis.
Author: Pinheiro, Hugo|Carvalho, Joana|Oliveira, Patricia|Ferreira, Daniel|Pinto, Marta Teixeira|Osorio, Hugo|Licastro, Danilo|Bordeira-Carrico, Renata|Jordan, Peter|Lazarevic, Dejan|Sanges, Remo|Stupka, Elia|Huntsman, David|Seruca, Raquel|Oliveira, Carla
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Journal: Cancer J. 2012 Jul-Aug;18(4):355-63.
Title: Genetic testing by cancer site: stomach.
Author: Chun, Nicki|Ford, James M
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Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2012 Jul;15(7):710-4.
Title: [Methylation status of CDH1 gene in preoperative abdominal lavage of patients with gastric cancer and its clinical significance].
Author: Luo, Jun|Wang, Xin-bao|Yu, Qi-ming|Zhao, Ting|Fang, Ren-gui|Wang, Jian-jun|Zheng, Zhi-guo|Yu, Jiang-liu|Fang, Xian-hua|Wang, Shi|Ling, Zhi-qiang
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Journal: Klin Onkol. 2012;25 Suppl:S30-3.
Title: [Hereditary diffuse gastric cancer].
Author: Puchmajerova, A|Vasovcak, P|Machackova, E|Foretova, L|Krepelova, A
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Journal: Infect Agent Cancer. 2012 Aug 28;7(1):21.
Title: Epstein-barr virus infected gastric adenocarcinoma expresses latent and lytic viral transcripts and has a distinct human gene expression profile.
Author: Tang, Weihua|Morgan, Douglas R|Meyers, Michael O|Dominguez, Ricardo L|Martinez, Enrique|Kakudo, Kennichi|Kuan, Pei Fen|Banet, Natalie|Muallem, Hind|Woodward, Kimberly|Speck, Olga|Gulley, Margaret L
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Journal: Nihon Rinsho. 2012 Oct;70(10):1705-14.
Title: [Genetic and epigenetic alterations in gastric carcinogenesis].
Author: Ushijima, Toshikazu|Yoshida, Satoshi
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Journal: J Surg Case Rep. 2012 Jun 1;2012(6):14.
Title: Prevention is better than cure.
Author: Daunton, A|Puig, S|Taniere, P|Forde, C|Alderson, D|Tucker, On
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Journal: Clin Exp Med. 2013 May;13(2):149-57.
Title: A novel CDH1 germline missense mutation in a sporadic gastric cancer patient in north-east of Italy.
Author: Garziera, Marica|De Re, Valli|Geremia, Silvano|Seruca, Raquel|Figueiredo, Joana|Melo, Soraia|Simoes-Correia, Joana|Caggiari, Laura|De Zorzi, Mariangela|Canzonieri, Vincenzo|Cannizzaro, Renato|Toffoli, Giuseppe
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Journal: Ann Surg Oncol. 2013 Feb;20(2):533-41.
Title: A RAND/UCLA appropriateness study of the management of familial gastric cancer.
Author: Dixon, Matthew|Seevaratnam, Rajini|Wirtzfeld, Debrah|McLeod, Robin|Helyer, Lucy|Law, Calvin|Swallow, Carol|Paszat, Lawrence|Bocicariu, Alina|Cardoso, Roberta|Mahar, Alyson|Bekaii-Saab, Tanios|Chau, Ian|Church, Neal|Coit, Daniel|Crane, Christopher H|Earle,
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Journal: Cancer Lett. 2013 Mar 1;330(1):33-40.
Title: Comprehensive DNA methylation and extensive mutation analyses reveal an association between the CpG island methylator phenotype and oncogenic mutations in gastric cancers.
Author: Kim, Jeong Goo|Takeshima, Hideyuki|Niwa, Tohru|Rehnberg, Emil|Shigematsu, Yasuyuki|Yoda, Yukie|Yamashita, Satoshi|Kushima, Ryoji|Maekita, Takao|Ichinose, Masao|Katai, Hitoshi|Park, Won Sang|Hong, Young Seon|Park, Cho Hyun|Ushijima, Toshikazu
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Journal: J Pathol. 2013 Mar;229(4):621-9.
Title: An alpha-E-catenin (CTNNA1) mutation in hereditary diffuse gastric cancer.
Author: Majewski, Ian J|Kluijt, Irma|Cats, Annemieke|Scerri, Thomas S|de Jong, Daphne|Kluin, Roelof J C|Hansford, Samantha|Hogervorst, Frans B L|Bosma, Astrid J|Hofland, Ingrid|Winter, Marcel|Huntsman, David|Jonkers, Jos|Bahlo, Melanie|Bernards, Rene
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Journal: Fam Cancer. 2013 Sep;12(3):503-7.
Title: Searching for E-cadherin gene mutations in early onset diffuse gastric cancer and hereditary diffuse gastric cancer in Korean patients.
Author: Kim, Sollip|Chung, Jun-Won|Jeong, Tae-Dong|Park, Young-Soo|Lee, Jeong Hoon|Ahn, Ji Yong|Kim, Do Hoon|Choi, Kee Don|Lee, Woochang|Song, Ho June|Lee, Gin Hyug|Chun, Sail|Jung, Hwoon-Yong|Min, Won-Ki|Kim, Jin-Ho
PMID: 23264079
Journal: J Clin Oncol. 2013 Mar 1;31(7):868-75.
Title: Somatic mutations and deletions of the E-cadherin gene predict poor survival of patients with gastric cancer.
Author: Corso, Giovanni|Carvalho, Joana|Marrelli, Daniele|Vindigni, Carla|Carvalho, Beatriz|Seruca, Raquel|Roviello, Franco|Oliveira, Carla
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Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2013 Jan;33(1):125-7.
Title: [E-cadherin expression and CDH1 promoter methylation in sporadic and hereditary gastric cancer].
Author: Li, Xiao-Jun|Zhao, Yang|Ren, Hong
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Journal: Gan To Kagaku Ryoho. 2013 Feb;40(2):154-8.
Title: [Familial gastric cancer - an update of Japanese cases].
Author: Sugimura, Haruhiko|Yamada, Hidetaka|Tao, Hong|Shinmura, Kazuya|Iwaizumi, Moriya|Kasami, Masako
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Journal: World J Gastroenterol. 2013 Feb 14;19(6):909-16.
Title: Novel CDH1 germline mutations identified in Chinese gastric cancer patients.
Author: Chen, Qin-Hua|Deng, Wei|Li, Xiao-Wei|Liu, Xiu-Fang|Wang, Jing-Mei|Wang, Li-Feng|Xiao, Nong|He, Qiong|Wang, Ya-Ping|Fan, Yi-Mei
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Journal: Fam Cancer. 2013 Sep;12(3):547-54.
Title: Mutation screen and RNA analysis disclose the changed splicing of the E-cadherin transcription in gastric cancer.
Author: Li, Xiaowei|Gao, Yafan|Pan, Yiyuan|Pan, Yan|Wang, Lifeng|Xiao, Nong|He, Qiong|Fan, Yimei|Wang, Yaping
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Journal: Prog Mol Biol Transl Sci. 2013;116:337-59.
Title: E-cadherin alterations in hereditary disorders with emphasis on hereditary diffuse gastric cancer.
Author: Oliveira, Carla|Pinheiro, Hugo|Figueiredo, Joana|Seruca, Raquel|Carneiro, Fatima
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Journal: Tumour Biol. 2013 Aug;34(4):2127-33.
Title: Analysis of the methylation patterns of the p16 INK4A, p15 INK4B, and APC genes in gastric adenocarcinoma patients from a Brazilian population.
Author: do Nascimento Borges, Barbara|Burbano, Rommel Mario Rodriguez|Harada, Maria Lucia
PMID: 23504555
Journal: Biomed Res Int. 2013;2013:396272.
Title: Molecular and survival differences between familial and sporadic gastric cancers.
Author: Fang, Wen-Liang|Chang, Shih-Ching|Lan, Yuan-Tzu|Huang, Kuo-Hung|Lo, Su-Shun|Li, Anna Fen-Yau|Chi, Chin-Wen|Wu, Chew-Wun|Chiou, Shih-Hwa
PMID: 23555086
Journal: J Med Genet. 2013 Jul;50(7):486-9.
Title: CDH1 germline mutations and the hereditary diffuse gastric and lobular breast cancer syndrome: a multicentre study.
Author: Benusiglio, Patrick R|Malka, David|Rouleau, Etienne|De Pauw, Antoine|Buecher, Bruno|Nogues, Catherine|Fourme, Emmanuelle|Colas, Chrystelle|Coulet, Florence|Warcoin, Mathilde|Grandjouan, Sophie|Sezeur, Alain|Laurent-Puig, Pierre|Moliere, Diane|Tlemsani, Ca
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Journal: BMC Gastroenterol. 2013 Jul 12;13:114.
Title: Synchronous appendiceal and intramucosal gastric signet ring cell carcinomas in an individual with CDH1-associated hereditary diffuse gastric carcinoma: a case report of a novel association and review of the literature.
Author: Hamilton, Leslie E|Jones, Kirsten|Church, Neal|Medlicott, Shaun
PMID: 23849133
Journal: Cancer Prev Res (Phila). 2013 Oct;6(10):1093-100.
Title: Examination of whole blood DNA methylation as a potential risk marker for gastric cancer.
Author: Tahara, Tomomitsu|Maegawa, Shinji|Chung, Woonbok|Garriga, Judith|Jelinek, Jaroslav|Estecio, Marcos R H|Shibata, Tomoyuki|Hirata, Ichiro|Arisawa, Tomiyasu|Issa, Jean-Pierre J
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Journal: Expert Opin Ther Targets. 2013 Oct;17(10):1187-201.
Title: Therapeutic targets associated to E-cadherin dysfunction in gastric cancer.
Author: Carneiro, Patricia|Figueiredo, Joana|Bordeira-Carrico, Renata|Fernandes, Maria Sofia|Carvalho, Joana|Oliveira, Carla|Seruca, Raquel
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Journal: Helicobacter. 2013 Sep;18 Suppl 1:34-8.
Title: Gastric cancer: epidemiologic aspects.
Author: Gonzalez, Carlos A|Sala, Nuria|Rokkas, Theodore
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Journal: Anticancer Res. 2013 Sep;33(9):3765-74.
Title: Frequent promoter methylation of CDH1 in non-neoplastic mucosa of sporadic diffuse gastric cancer.
Author: Lee, Kyung Hwa|Hwang, David|Kang, Ki Young|Lee, Soong|Kim, Dong Yi|Joo, Young Eun|Lee, Jae Hyuk
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Journal: Nat Rev Clin Oncol. 2013 Nov;10(11):643-55.
Title: Gastric cancer-molecular and clinical dimensions.
Author: Wadhwa, Roopma|Song, Shumei|Lee, Ju-Seog|Yao, Yixin|Wei, Qingyi|Ajani, Jaffer A
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Journal: PLoS One. 2013 Oct 29;8(10):e77035.
Title: Identification and characterization of CDH1 germline variants in sporadic gastric cancer patients and in individuals at risk of gastric cancer.
Author: Garziera, Marica|Canzonieri, Vincenzo|Cannizzaro, Renato|Geremia, Silvano|Caggiari, Laura|De Zorzi, Mariangela|Maiero, Stefania|Orzes, Enrico|Perin, Tiziana|Zanussi, Stefania|De Paoli, Paolo|De Re, Valli
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Journal: Vopr Onkol. 2013;59(5):580-4.
Title: [Molecular genetics study of hereditary predisposition to diffuse gastric cancer in Russian patients].
Author: Tsukanov, A C|Shelygin, Iu A|Kashnikov, V N|Frolov, S A|Liubchenko, L N|Shubin, V P|Karpukhin, A V|Muzaffarova, T A|Pospekhova, N I
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Journal: J Tradit Chin Med. 2013 Oct;33(5):572-9.
Title: Association among lifestyle, clinical examination, polymorphisms in CDH1 gene and Traditional Chinese Medicine syndrome differentiation of gastric cancer.
Author: Zhang, Junfeng|Zhan, Zhen|Wu, Juan|Zhang, Chunbing|Yang, Yaping|Tong, Shujuan|Wang, Ruiping|Yang, Xuewen|Dong, Wei
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Journal: Mol Biol (Mosk). 2013 Sep-Oct;47(5):835-41.
Title: [Allelic imbalance of loci 17p13.1 (TP53), 1p36.1 (RUNX3), 16p22 (CDH1) and microsatellite instability in gastric cancer].
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Journal: Gastric Cancer. 2014 Oct;17(4):745-9.
Title: Early-onset diffuse gastric cancer associated with a de novo large genomic deletion of CDH1 gene.
Author: Sugimoto, Shinya|Yamada, Hidetaka|Takahashi, Masazumi|Morohoshi, Yuichi|Yamaguchi, Naotaka|Tsunoda, Yuya|Hayashi, Hiroyuki|Sugimura, Haruhiko|Komatsu, Hirokazu
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Journal: Eur J Gastroenterol Hepatol. 2014 Mar;26(3):353-6.
Title: Prophylactic gastrectomy in a 16-year-old.
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Journal: Carcinogenesis. 2014 Apr;35(4):867-76.
Title: Reduced expression of the chromatin remodeling gene ARID1A enhances gastric cancer cell migration and invasion via downregulation of E-cadherin transcription.
Author: Yan, Hai-Bo|Wang, Xue-Fei|Zhang, Qian|Tang, Zhao-Qing|Jiang, Ying-Hua|Fan, Hui-Zhi|Sun, Yi-hong|Yang, Peng-Yuan|Liu, Feng
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Journal: Hum Mol Genet. 2014 Apr 15;23(8):2094-105.
Title: DNAJB4 molecular chaperone distinguishes WT from mutant E-cadherin, determining their fate in vitro and in vivo.
Author: Simoes-Correia, Joana|Silva, Diana I|Melo, Soraia|Figueiredo, Joana|Caldeira, Joana|Pinto, Marta T|Girao, Henrique|Pereira, Paulo|Seruca, Raquel
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Journal: Fam Cancer. 2014 Jun;13(2):231-42.
Title: Prophylactic total gastrectomy in hereditary diffuse gastric cancer: identification of two novel CDH1 gene mutations-a clinical observational study.
Author: Bardram, Linda|Hansen, Thomas V O|Gerdes, Anne-Marie|Timshel, Susanne|Friis-Hansen, Lennart|Federspiel, Birgitte
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Journal: Eur J Hum Genet. 2014 Sep;22(9):1085-92.
Title: Rescue of wild-type E-cadherin expression from nonsense-mutated cancer cells by a suppressor-tRNA.
Author: Bordeira-Carrico, Renata|Ferreira, Daniel|Mateus, Denisa D|Pinheiro, Hugo|Pego, Ana Paula|Santos, Manuel A S|Oliveira, Carla
PMID: 24424122
Journal: Ann Surg. 2014 Jul;260(1):87-93.
Title: The impact of prophylactic total gastrectomy on health-related quality of life: a prospective cohort study.
Author: Worster, Elizabeth|Liu, Xinxue|Richardson, Susan|Hardwick, Richard H|Dwerryhouse, Sarah|Caldas, Carlos|Fitzgerald, Rebecca C
PMID: 24424140
Journal: Gastrointest Endosc. 2014 Jul;80(1):78-87.
Title: Prospective cohort study assessing outcomes of patients from families fulfilling criteria for hereditary diffuse gastric cancer undergoing endoscopic surveillance.
Author: Lim, Yean Cheant|di Pietro, Massimiliano|O'Donovan, Maria|Richardson, Susan|Debiram, Irene|Dwerryhouse, Susan|Hardwick, Richard H|Tischkowitz, Marc|Caldas, Carlos|Ragunath, Krish|Fitzgerald, Rebecca C
PMID: 24472763
Journal: Genes Chromosomes Cancer. 2014 May;53(5):432-45.
Title: Complementary molecular approaches reveal heterogeneous CDH1 germline defects in Italian patients with hereditary diffuse gastric cancer (HDGC) syndrome.
Author: Molinaro, Valeria|Pensotti, Valeria|Marabelli, Monica|Feroce, Irene|Barile, Monica|Pozzi, Simonetta|Laghi, Luigi|Serrano, Davide|Bernard, Loris|Bonanni, Bernardo|Ranzani, Guglielmina Nadia
PMID: 24493355
Journal: World J Surg Oncol. 2014 Mar 31;12:80.
Title: CDH1 polymorphisms and haplotypes in sporadic diffuse and intestinal gastric cancer: a case-control study based on direct sequencing analysis.
Author: Chu, Chi-Ming|Chen, Cheng-Jueng|Chan, De-Chuan|Wu, Hurng-Sheng|Liu, Yao-Chi|Shen, Chen-Yang|Chang, Tzu-Ming|Yu, Jyh-Cherng|Harn, Horng-Jyh|Yu, Cheng-Ping|Yang, Ming-Hsin
PMID: 24684952
Journal: Genome Biol. 2014 Apr 1;15(4):R55.
Title: Genomic profile analysis of diffuse-type gastric cancers.
Author: Lee, Yeon-Su|Cho, Yun Sung|Lee, Geon Kook|Lee, Sunghoon|Kim, Young-Woo|Jho, Sungwoong|Kim, Hak-Min|Hong, Seung-Hyun|Hwang, Jung-Ah|Kim, Sook-young|Hong, Dongwan|Choi, Il Ju|Kim, Byung Chul|Kim, Byoung-Chul|Kim, Chul Hong|Choi, Hansol|Kim, Youngju|Kim, Kyu
PMID: 24690483
Journal: Arch Iran Med. 2014 Apr;17(4):286-92.
Title: Cancers of the upper gastro-intestinal tract: a review of somatic mutation distributions.
Author: Abedi-Ardekani, Behnoush|Hainaut, Pierre
PMID: 24724606
Journal: Int J Oncol. 2014 Jun;44(6):1955-70.
Title: Gene expression signatures for identifying diffuse-type gastric cancer associated with epithelial-mesenchymal transition.
Author: Tanabe, Shihori|Aoyagi, Kazuhiko|Yokozaki, Hiroshi|Sasaki, Hiroki
PMID: 24728500
Journal: Scand J Gastroenterol. 2014 Aug;49(8):974-8.
Title: The normal neuroendocrine cells of the upper gastrointestinal tract lack E-cadherin.
Author: Waldum, Helge L|Ringnes, Eva|Nordbo, Helene|Sordal, Oystein|Nordrum, Ivar S|Hauso, Oyvind
PMID: 24742175
Journal: Mol Cancer Res. 2014 Aug;12(8):1088-99.
Title: Cooperativity of E-cadherin and Smad4 loss to promote diffuse-type gastric adenocarcinoma and metastasis.
Author: Park, Jun Won|Jang, Seok Hoon|Park, Dong Min|Lim, Na Jung|Deng, Chuxia|Kim, Dae Yong|Green, Jeffrey E|Kim, Hark Kyun
PMID: 24784840
Journal: Adv Med Sci. 2014 Mar;59(1):142-6.
Title: Gastric cancer patients less than 50 years of age exhibit significant downregulation of E-cadherin and CDX2 compared to older reference populations.
Author: Schildberg, Claus Wilhelm|Abba, Mohammed|Merkel, Susanne|Agaimy, Abbas|Dimmler, Arno|Schlabrakowski, Anne|Croner, Roland|Leupold, Jorg Hendrik|Hohenberger, Werner|Allgayer, Heike
PMID: 24797991
Journal: Nat Genet. 2014 Jun;46(6):573-82.
Title: Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer.
Author: Wang, Kai|Yuen, Siu Tsan|Xu, Jiangchun|Lee, Siu Po|Yan, Helen H N|Shi, Stephanie T|Siu, Hoi Cheong|Deng, Shibing|Chu, Kent Man|Law, Simon|Chan, Kok Hoe|Chan, Annie S Y|Tsui, Wai Yin|Ho, Siu Lun|Chan, Anthony K W|Man, Jonathan L K|Foglizzo, Valentina|Ng, M
PMID: 24816253
Journal: Med Oncol. 2014 Jun;31(6):988.
Title: p16 Methylation is associated with chemosensitivity to fluorouracil in patients with advanced gastric cancer.
Author: Wang, Mingming|Li, Yilin|Gao, Jing|Li, Yanyan|Zhou, Jing|Gu, Liankun|Shen, Lin|Deng, Dajun
PMID: 24816738
Journal: Fam Cancer. 2014 Sep;13(3):415-21.
Title: Nucleotide variants of the cancer predisposing gene CDH1 and the risk of non-syndromic cleft lip with or without cleft palate.
Author: Hozyasz, Kamil K|Mostowska, Adrianna|Wojcicki, Piotr|Lasota, Agnieszka|Offert, Barbara|Balcerek, Adam|Dunin-Wilczynska, Izabella|Jagodzinski, Pawel P
PMID: 24838934
Journal: Asian Pac J Cancer Prev. 2014;15(8):3705-13.
Title: Roles of E-cadherin (CDH1) genetic variations in cancer risk: a meta-analysis.
Author: Deng, Qi-Wen|He, Bang-Shun|Pan, Yu-Qin|Sun, Hui-Ling|Xu, Ye-Qiong|Gao, Tian-Yi|Li, Rui|Song, Guo-Qi|Wang, Shu-Kui
PMID: 24870781
Journal: J Surg Oncol. 2014 Nov;110(6):727-33.
Title: CD44(+) CD324(-) expression and prognosis in gastric cancer patients.
Author: Cao, Liang|Hu, Xiang|Zhang, Jian|Liang, Pin|Zhang, Yi
PMID: 24910454
Journal: Clin Res Hepatol Gastroenterol. 2014 Oct;38(5):613-20.
Title: Different methylation profiles between intestinal and diffuse sporadic gastric carcinogenesis.
Author: Yang, Misuk|Kim, Hyun-Soo|Cho, Mee Yon
PMID: 24953529
Journal: Hered Cancer Clin Pract. 2014 Jul 19;12(1):17.
Title: Sequence-based detection of mutations in cadherin 1 to determine the prevalence of germline mutations in patients with invasive lobular carcinoma of the breast.
Author: Valente, Allyson L|Rummel, Seth|Shriver, Craig D|Ellsworth, Rachel E
PMID: 25067988
Journal: Hawaii J Med Public Health. 2014 Jul;73(7):204-7.
Title: Hereditary diffuse gastric cancer associated with E-cadherin germline mutation: a case report.
Author: Black, Michael D|Kaneshiro, Raynette|Lai, Jennifer I|Shimizu, David M
PMID: 25089230
Journal: Hered Cancer Clin Pract. 2014 Aug 13;12(1):18.
Title: Genetic screening analysis of patients with hereditary diffuse gastric cancer from northern and northeastern Brazil.
Author: Moreira-Nunes, Caroline Aquino|Barros, Mariceli Baia Leao|do Nascimento Borges, Barbara|Montenegro, Raquel Carvalho|Lamarao, Leticia Martins|Ribeiro, Helem Ferreira|Bona, Amanda Braga|Assumpcao, Paulo Pimentel|Rey, Juan Antonio|Pinto, Giovanny Reboucas|Bu
PMID: 25180051
Journal: Genome Biol. 2014 Aug 27;15(8):428.
Title: Metastatic tumor evolution and organoid modeling implicate TGFBR2 as a cancer driver in diffuse gastric cancer.
Author: Nadauld, Lincoln D|Garcia, Sarah|Natsoulis, Georges|Bell, John M|Miotke, Laura|Hopmans, Erik S|Xu, Hua|Pai, Reetesh K|Palm, Curt|Regan, John F|Chen, Hao|Flaherty, Patrick|Ootani, Akifumi|Zhang, Nancy R|Ford, James M|Kuo, Calvin J|Ji, Hanlee P
PMID: 25315765
Journal: Cancer Metastasis Rev. 2014 Dec;33(4):1081-94.
Title: E-cadherin germline mutation carriers: clinical management and genetic implications.
Author: Corso, Giovanni|Figueiredo, Joana|Biffi, Roberto|Trentin, Chiara|Bonanni, Bernardo|Feroce, Irene|Serrano, Davide|Cassano, Enrico|Annibale, Bruno|Melo, Soraia|Seruca, Raquel|De Lorenzi, Francesca|Ferrara, Francesco|Piagnerelli, Riccardo|Roviello, Franco|Ga
PMID: 25332147
Journal: Medicine (Baltimore). 2014 Oct;93(19):e107.
Title: Association of genetic variants in and promoter hypermethylation of CDH1 with gastric cancer: a meta-analysis.
Author: Jing, Huiquan|Dai, Fei|Zhao, Chuntao|Yang, Juan|Li, Lizhuo|Kota, Pravina|Mao, Lijuan|Xiang, Kaimin|Zheng, Changqing|Yang, Jingyun
PMID: 25340495
Journal: PLoS Genet. 2014 Oct 23;10(10):e1004669.
Title: Germline mutations in MAP3K6 are associated with familial gastric cancer.
Author: Gaston, Daniel|Hansford, Samantha|Oliveira, Carla|Nightingale, Mathew|Pinheiro, Hugo|Macgillivray, Christine|Kaurah, Pardeep|Rideout, Andrea L|Steele, Patricia|Soares, Gabriela|Huang, Weei-Yuarn|Whitehouse, Scott|Blowers, Sarah|LeBlanc, Marissa A|Jiang, H
PMID: 25340522
Journal: Mutat Res. 2014 Dec;770:106-11.
Title: The germline CDH1 c.48 G>C substitution contributes to cancer predisposition through generation of a pro-invasive mutation.
Author: Zhang, Liying|Xiao, Alexander|Ruggeri, Jeanine|Bacares, Ruben|Somar, Joshua|Melo, Soraia|Figueiredo, Joana|Simoes-Correia, Joana|Seruca, Raquel|Shah, Manish A
PMID: 25771876
Journal: Gastric Cancer. 2015 Jan;18(1):65-76.
Title: Integrated analysis of cancer-related pathways affected by genetic and epigenetic alterations in gastric cancer.
Author: Yoda, Yukie|Takeshima, Hideyuki|Niwa, Tohru|Kim, Jeong Goo|Ando, Takayuki|Kushima, Ryoji|Sugiyama, Toshiro|Katai, Hitoshi|Noshiro, Hirokazu|Ushijima, Toshikazu
PMID: 24510342
Journal: Mol Carcinog. 2015 Nov;54(11):1521-7.
Title: Establishment and characterization of metastatic gastric cancer cell lines from murine gastric adenocarcinoma lacking Smad4, p53, and E-cadherin.
Author: Park, Jun Won|Park, Dong Min|Choi, Beom K|Kwon, Byoung S|Seong, Je Kyung|Green, Jeffrey E|Kim, Dae-Yong|Kim, Hark Kyun
PMID: 25307412
Journal: Fam Cancer. 2015 Jun;14(2):241-6.
Title: Exome sequencing reveals three novel candidate predisposition genes for diffuse gastric cancer.
Author: Donner, Iikki|Kiviluoto, Tuula|Ristimaki, Ari|Aaltonen, Lauri A|Vahteristo, Pia
PMID: 25576241
Journal: Sci Rep. 2015 Jan 20;5:7891.
Title: Lack of association between the CDH1 polymorphism and gastric cancer susceptibility: a meta-analysis.
Author: Jiang, Benchun|Zhu, Ke|Shao, Hua|Bao, Chenhui|Ou, Jinlei|Sun, Wei
PMID: 25599647
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2015 Jan;35(1):125-7.
Title: [E-cadherin expression and CDH1 promoter methylation in sporadic and hereditary gastric cancer].
Author: Li, Xiao-Jun|Zhao, Yang|Ren, Hong
PMID: 25613626
Journal: Lancet Oncol. 2015 Feb;16(2):e60-70.
Title: Familial gastric cancer: genetic susceptibility, pathology, and implications for management.
Author: Oliveira, Carla|Pinheiro, Hugo|Figueiredo, Joana|Seruca, Raquel|Carneiro, Fatima
PMID: 25638682
Journal: Mol Cancer Ther. 2015 May;14(5):1213-23.
Title: Synthetic Lethal Screens Identify Vulnerabilities in GPCR Signaling and Cytoskeletal Organization in E-Cadherin-Deficient Cells.
Author: Telford, Bryony J|Chen, Augustine|Beetham, Henry|Frick, James|Brew, Tom P|Gould, Cathryn M|Single, Andrew|Godwin, Tanis|Simpson, Kaylene J|Guilford, Parry
PMID: 25777964
Journal: Gastroenterol Res Pract. 2015;2015:896560.
Title: From molecular classification to targeted therapeutics: the changing face of systemic therapy in metastatic gastroesophageal cancer.
Author: Murphy, Adrian|Kelly, Ronan J
PMID: 25784931
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2015 Mar;18(3):295-7.
Title: [Current status of the study on hereditary diffuse gastric cancer].
Author: Wang, Xicheng|Shen, Lin
PMID: 25809335
Journal: J Gastrointestin Liver Dis. 2015 Mar;24(1):77-83.
Title: The Lauren classification highlights the role of epithelial-to-mesenchymal transition in gastric carcinogenesis: an immunohistochemistry study of the STAT3 and adhesion molecules expression.
Author: Susman, Sergiu|Barnoud, Raphaelle|Bibeau, Frederique|Borini, Francesco|Pocard, Marc|Tomuleasa, Ciprian|Sabourin, Jean-Cristophe
PMID: 25822437
Journal: Breast Cancer Res. 2015 Mar 13;17:37.
Title: Lobular breast cancer: incidence and genetic and non-genetic risk factors.
Author: Dossus, Laure|Benusiglio, Patrick R
PMID: 25848941
Journal: PLoS One. 2015 Apr 15;10(4):e0123926.
Title: Deregulation between miR-29b/c and DNMT3A is associated with epigenetic silencing of the CDH1 gene, affecting cell migration and invasion in gastric cancer.
Author: Cui, He|Wang, Ling|Gong, Pihai|Zhao, Chengcheng|Zhang, Shaodan|Zhang, Kun|Zhou, Rongping|Zhao, Zhujiang|Fan, Hong
PMID: 25874772
Journal: Oncologist. 2015 May;20(5):499-507.
Title: Prospective comprehensive genomic profiling of advanced gastric carcinoma cases reveals frequent clinically relevant genomic alterations and new routes for targeted therapies.
Author: Ali, Siraj M|Sanford, Eric M|Klempner, Samuel J|Rubinson, Douglas A|Wang, Kai|Palma, Norma A|Chmielecki, Juliann|Yelensky, Roman|Palmer, Gary A|Morosini, Deborah|Lipson, Doron|Catenacci, Daniel V|Braiteh, Fadi|Erlich, Rachel|Stephens, Philip J|Ross, Jeffr
PMID: 25882375
Journal: Drug Des Devel Ther. 2015 Apr 13;9:2149-57.
Title: The clinicopathological significance of CDH1 in gastric cancer: a meta-analysis and systematic review.
Author: Zeng, Wei|Zhu, Jinfeng|Shan, Li|Han, Zhigang|Aerxiding, Patiguli|Quhai, Amina|Zeng, Fanye|Wang, Ziwei|Li, Huiwu
PMID: 25926721
Journal: J Med Genet. 2015 Jun;52(6):361-74.
Title: Hereditary diffuse gastric cancer: updated clinical guidelines with an emphasis on germline CDH1 mutation carriers.
Author: van der Post, Rachel S|Vogelaar, Ingrid P|Carneiro, Fatima|Guilford, Parry|Huntsman, David|Hoogerbrugge, Nicoline|Caldas, Carlos|Schreiber, Karen E Chelcun|Hardwick, Richard H|Ausems, Margreet G E M|Bardram, Linda|Benusiglio, Patrick R|Bisseling, Tanya M|
PMID: 25979631
Journal: Ann Surg Oncol. 2015 Dec;22 Suppl 3:S915-22.
Title: A Long Non-coding RNA Activated by Transforming Growth Factor-beta is an Independent Prognostic Marker of Gastric Cancer.
Author: Saito, Tomoko|Kurashige, Junji|Nambara, Sho|Komatsu, Hisateru|Hirata, Hidenari|Ueda, Masami|Sakimura, Shotaro|Uchi, Ryutaro|Takano, Yuki|Shinden, Yoshiaki|Iguchi, Tomohiro|Eguchi, Hidetoshi|Ehata, Shogo|Murakami, Kazunari|Sugimachi, Keishi|Mimori, Koshi
PMID: 25986864
Journal: Diagn Pathol. 2015 Jun 2;10:59.
Title: Association between human papillomavirus and Epstein - Barr virus DNA and gene promoter methylation of RB1 and CDH1 in the cervical lesions: a transversal study.
Author: McCormick, Thais M|Canedo, Nathalie H S|Furtado, Yara L|Silveira, Filomena A|de Lima, Roberto J|Rosman, Andrea D F|Almeida Filho, Gutemberg L|Carvalho, Maria da Gloria da C
PMID: 26032781
Journal: Cancer Sci. 2015 Aug;106(8):951-8.
Title: Clinicopathologic and molecular characteristics of gastric cancer showing gastric and intestinal mucin phenotype.
Author: Oue, Naohide|Sentani, Kazuhiro|Sakamoto, Naoya|Yasui, Wataru
PMID: 26033320
Journal: Gastroenterology. 2015 Oct;149(4):897-906.e19.
Title: Accuracy of Hereditary Diffuse Gastric Cancer Testing Criteria and Outcomes in Patients With a Germline Mutation in CDH1.
Author: van der Post, Rachel S|Vogelaar, Ingrid P|Manders, Peggy|van der Kolk, Lizet E|Cats, Annemieke|van Hest, Liselotte P|Sijmons, Rolf|Aalfs, Cora M|Ausems, Margreet G E M|Gomez Garcia, Encarna B|Wagner, Anja|Hes, Frederik J|Arts, Neeltje|Mensenkamp, Arjen R|
PMID: 26072394
Journal: Cell Death Dis. 2015 Jul 2;6:e1802.
Title: LincHOTAIR epigenetically silences miR34a by binding to PRC2 to promote the epithelial-to-mesenchymal transition in human gastric cancer.
Author: Liu, Y-w|Sun, M|Xia, R|Zhang, E-b|Liu, X-h|Zhang, Z-h|Xu, T-p|De, W|Liu, B-r|Wang, Z-x
PMID: 26136075
Journal: JAMA Oncol. 2015 Apr;1(1):23-32.
Title: Hereditary Diffuse Gastric Cancer Syndrome: CDH1 Mutations and Beyond.
Author: Hansford, Samantha|Kaurah, Pardeep|Li-Chang, Hector|Woo, Michelle|Senz, Janine|Pinheiro, Hugo|Schrader, Kasmintan A|Schaeffer, David F|Shumansky, Karey|Zogopoulos, George|Santos, Teresa Almeida|Claro, Isabel|Carvalho, Joana|Nielsen, Cydney|Padilla, Sarah|
PMID: 26182300
Journal: Hum Mol Genet. 2015 Oct 15;24(20):5891-900.
Title: E-cadherin-defective gastric cancer cells depend on Laminin to survive and invade.
Author: Caldeira, Joana|Figueiredo, Joana|Bras-Pereira, Catarina|Carneiro, Patricia|Moreira, Ana M|Pinto, Marta T|Relvas, Joao B|Carneiro, Fatima|Barbosa, Mario|Casares, Fernando|Janody, Florence|Seruca, Raquel
PMID: 26246502
Journal: Carcinogenesis. 2015 Nov;36(11):1363-71.
Title: miR-544a induces epithelial-mesenchymal transition through the activation of WNT signaling pathway in gastric cancer.
Author: Yanaka, Yoshimitsu|Muramatsu, Tomoki|Uetake, Hiroyuki|Kozaki, Ken-ichi|Inazawa, Johji
PMID: 26264654
Journal: Cancer Epidemiol Biomarkers Prev. 2015 Oct;24(10):1607-13.
Title: DNA Methylation Predicts Progression of Human Gastric Lesions.
Author: Schneider, Barbara G|Mera, Robertino|Piazuelo, M Blanca|Bravo, Juan C|Zabaleta, Jovanny|Delgado, Alberto G|Bravo, Luis E|Wilson, Keith T|El-Rifai, Wael|Peek, Richard M Jr|Correa, Pelayo
PMID: 26269563
Journal: Oncotarget. 2015 Sep 29;6(29):26935-45.
Title: Deregulation of ARID1A, CDH1, cMET and PIK3CA and target-related microRNA expression in gastric cancer.
Author: Ibarrola-Villava, Maider|Llorca-Cardenosa, Marta J|Tarazona, Noelia|Mongort, Cristina|Fleitas, Tania|Perez-Fidalgo, Jose Alejandro|Rosello, Susana|Navarro, Samuel|Ribas, Gloria|Cervantes, Andres
PMID: 26334097
Journal: Surg Oncol Clin N Am. 2015 Oct;24(4):765-77.
Title: Hereditary Gastric Cancer Syndromes.
Author: Colvin, Hugh|Yamamoto, Ken|Wada, Noriko|Mori, Masaki
PMID: 26363540
Journal: Tumour Biol. 2015 Sep;36(10):7385-94.
Title: Gene mutations in gastric cancer: a review of recent next-generation sequencing studies.
Author: Lin, Y|Wu, Z|Guo, W|Li, J
PMID: 26364057
Journal: J Gastrointest Surg. 2015 Dec;19(12):2120-5.
Title: Prophylactic Laparoscopic Total Gastrectomy with Jejunal Pouch Reconstruction in Patients Carrying a CDH1 Germline Mutation.
Author: Haverkamp, L|van der Sluis, P C|Ausems, M G E M|van der Horst, S|Siersema, P D|Ruurda, J P|Offerhaus, G J A|van Hillegersberg, R
PMID: 26443527
Journal: Oncotarget. 2015 Dec 1;6(38):40953-8.
Title: Prevalence of deleterious ATM germline mutations in gastric cancer patients.
Author: Huang, Dong-Sheng|Tao, Hou-Quan|He, Xu-Jun|Long, Ming|Yu, Sheng|Xia, Ying-Jie|Wei, Zhang|Xiong, Zikai|Jones, Sian|He, Yiping|Yan, Hai|Wang, Xiaoyue
PMID: 26506520
Journal: BMC Cancer. 2015 Dec 16;15:954.
Title: Epigenetic regulation of CDH1 exon 8 alternative splicing in gastric cancer.
Author: Li, Xiao-Wei|Shi, Bing-Yu|Yang, Qing-Lan|Wu, Jie|Wu, Hui-Min|Wang, Yu-Feng|Wu, Zhi-Jiao|Fan, Yi-Mei|Wang, Ya-Ping
PMID: 26674321
Journal: Open Med (Wars). 2014 Nov 3;10(1):57-62.
Title: Correlation between SNPs in CDH1 and gastric cancer in Chinese population.
Author: Lin, Yijin|Yuan, Jintao|Wang, Lihui|Wang, Lan|Ma, Yunjia|Wang, Yuhua|Chen, Jianhong|Zhao, Hong
PMID: 28352678
Journal: Fam Cancer. 2016 Jan;15(1):41-7.
Title: Is there an association between invasive lobular carcinoma of the breast and a family history of gastric cancer?
Author: Chikman, Bar|Davidson, Tima|Kais, Hasan|Jeroukhimov, Igor|Leshno, Ari|Sandbank, Judith|Halevy, Ariel|Lavy, Ron
PMID: 26358115
Journal: Fam Cancer. 2016 Apr;15(2):215-9.
Title: CDH1 germline mutations and hereditary lobular breast cancer.
Author: Corso, Giovanni|Intra, Mattia|Trentin, Chiara|Veronesi, Paolo|Galimberti, Viviana
PMID: 26759166
Journal: Cancer Res. 2016 Apr 1;76(7):1724-32.
Title: Distinct Subtypes of Gastric Cancer Defined by Molecular Characterization Include Novel Mutational Signatures with Prognostic Capability.
Author: Li, Xiangchun|Wu, William K K|Xing, Rui|Wong, Sunny H|Liu, Yuexin|Fang, Xiaodong|Zhang, Yanlin|Wang, Mengyao|Wang, Jiaqian|Li, Lin|Zhou, Yong|Tang, Senwei|Peng, Shaoliang|Qiu, Kunlong|Chen, Longyun|Chen, Kexin|Yang, Huanming|Zhang, Wei|Chan, Matthew T V|L
PMID: 26857262
Journal: Drug Des Devel Ther. 2016 Mar 15;10:1159-60.
Title: Comments on a meta-analysis and systematic review of the clinicopathological significance of CDH1 in gastric cancer.
Author: Tu, Chao|Yuan, Lianwen|Zhou, Jianping
PMID: 27042007
Journal: Oncotarget. 2016 May 3;7(18):25391-407.
Title: Gelsolin-mediated activation of PI3K/Akt pathway is crucial for hepatocyte growth factor-induced cell scattering in gastric carcinoma.
Author: Huang, Baohua|Deng, Shuo|Loo, Ser Yue|Datta, Arpita|Yap, Yan Lin|Yan, Benedict|Ooi, Chia Huey|Dinh, Thuy Duong|Zhuo, Jingli|Tochhawng, Lalchhandami|Gopinadhan, Suma|Jegadeesan, Tamilarasi|Tan, Patrick|Salto-Tellez, Manuel|Yong, Wei Peng|Soong, Richie|Yeoh
PMID: 27058427
Journal: Mol Genet Genomic Med. 2016 Jan 13;4(2):232-6.
Title: Panel testing reveals nonsense and missense CDH1 mutations in families without hereditary diffuse gastric cancer.
Author: Huynh, Julie M|Laukaitis, Christina M
PMID: 27064202
Journal: Recent Results Cancer Res. 2016;205:45-60.
Title: Diagnosis and Management of Hereditary Gastric Cancer.
Author: Monahan, Kevin John|Hopkins, Laura
PMID: 27075348
Journal: Mol Med Rep. 2016 Jun;13(6):4767-73.
Title: MicroRNA-205 suppresses the invasion and epithelial-mesenchymal transition of human gastric cancer cells.
Author: Xu, Chang|Li, Ming'e|Zhang, Lin|Bi, Yueyang|Wang, Peiyuan|Li, Jun|Jiang, Xingyue
PMID: 27082508
Journal: Genet Mol Biol. 2016 May 13;39(2):189-98.
Title: CDH1 mutations in gastric cancer patients from northern Brazil identified by Next- Generation Sequencing (NGS).
Author: El-Husny, Antonette|Raiol-Moraes, Milene|Amador, Marcos|Ribeiro-Dos-Santos, Andre M|Montagnini, Andre|Barbosa, Silvanira|Silva, Artur|Assumpcao, Paulo|Ishak, Geraldo|Santos, Sidney|Pinto, Pablo|Cruz, Aline|Ribeiro-Dos-Santos, Andrea
PMID: 27192129
Journal: Fam Cancer. 2016 Oct;15(4):665-76.
Title: An investigation of the factors effecting high-risk individuals' decision-making about prophylactic total gastrectomy and surveillance for hereditary diffuse gastric cancer (HDGC).
Author: Hallowell, Nina|Badger, Shirlene|Richardson, Sue|Caldas, Carlos|Hardwick, Richard H|Fitzgerald, Rebecca C|Lawton, Julia
PMID: 27256430
Journal: Bull Cancer. 2016 Jul-Aug;103(7-8):643-50.
Title: [New molecular classification of colorectal cancer, pancreatic cancer and stomach cancer: Towards "a la carte" treatment?].
Author: Dreyer, Chantal|Afchain, Pauline|Trouilloud, Isabelle|Andre, Thierry
PMID: 27345450
Journal: Asian Pac J Cancer Prev. 2016;17(6):2757-60.
Title: Hypermethylation Status of E-Cadherin Gene in Gastric Cancer Patients in a High Incidence Area.
Author: Rashid, Haroon|Alam, Khursheed|Afroze, Dil|Yousuf, Adfar|Banday, Manzoor|Kawoosa, Fizalah
PMID: 27356686
Journal: Clin J Oncol Nurs. 2016 Aug 1;20(4):443-5.
Title: Cate's Story: Hereditary Diffuse Gastric Cancer.
Author: Rogers, Megan
PMID: 27441520
Journal: Biomed Rep. 2016 Aug;5(2):151-154.
Title: MicroRNAs in hereditary diffuse gastric cancer.
Author: Suarez-Arriaga, Mayra-Cecilia|Ribas-Aparicio, Rosa-Maria|Ruiz-Tachiquin, Martha-Eugenia
PMID: 27446532
Journal: Springerplus. 2016 Jul 26;5(1):1181.
Title: A novel mutation in the CDH1 gene in a Spanish family with hereditary diffuse gastric cancer.
Author: Lopez, Maria|Cervera-Acedo, Cristina|Santibanez, Paula|Salazar, Raquel|Sola, Jesus-Javier|Dominguez-Garrido, Elena
PMID: 27512640
Journal: Oncotarget. 2016 Sep 27;7(39):63424-63436.
Title: Epigenetic changes in localized gastric cancer: the role of RUNX3 in tumor progression and the immune microenvironment.
Author: Llorca-Cardenosa, Marta Jessica|Fleitas, Tania|Ibarrola-Villava, Maider|Pena-Chilet, Maria|Mongort, Cristina|Martinez-Ciarpaglini, Carolina|Navarro, Lara|Gambardella, Valentina|Castillo, Josefa|Rosello, Susana|Navarro, Samuel|Ribas, Gloria|Cervantes, Andr
PMID: 27566570
Journal: Adv Exp Med Biol. 2016;908:371-91.
Title: Histopathological, Molecular, and Genetic Profile of Hereditary Diffuse Gastric Cancer: Current Knowledge and Challenges for the Future.
Author: van der Post, Rachel S|Gullo, Irene|Oliveira, Carla|Tang, Laura H|Grabsch, Heike I|O'Donovan, Maria|Fitzgerald, Rebecca C|van Krieken, Han|Carneiro, Fatima
PMID: 27573781
Journal: Int J Colorectal Dis. 2016 Dec;31(12):1825-1833.
Title: Prophylactic total gastrectomy in the management of hereditary tumor syndromes.
Author: Pantelis, Dimitrios|Huneburg, Robert|Adam, Ronja|Holzapfel, Stefanie|Gevensleben, Heidrun|Nattermann, Jacob|Strassburg, Christian P|Aretz, Stefan|Kalff, Jorg C
PMID: 27682646
Journal: Genet Mol Res. 2016 Sep 16;15(3). pii: gmr8715.
Title: Association between the CDH1-472delA and -160C>A polymorphisms and diffuse and intestinal gastric cancer in a Mexican population.
Author: Bustos-Carpinteyro, A R|Delgado-Figueroa, N|Santiago-Luna, E|Magana-Torres, M T|Sanchez-Lopez, J Y
PMID: 27706737
Journal: J Gastrointest Surg. 2016 Dec;20(12):1950-1958.
Title: Prophylactic Total Gastrectomy: a Prospective Cohort Study of Long-Term Impact on Quality of Life.
Author: Muir, Jennifer|Aronson, Melyssa|Esplen, Mary-Jane|Pollett, Aaron|Swallow, Carol J
PMID: 27752808
Journal: PLoS One. 2016 Nov 23;11(11):e0165654.
Title: CDH1 Missense Variant c.1679C>G (p.T560R) Completely Disrupts Normal Splicing through Creation of a Novel 5' Splice Site.
Author: Yelskaya, Zarina|Bacares, Ruben|Salo-Mullen, Erin|Somar, Joshua|Lehrich, Deborah A|Fasaye, Grace-Ann|Coit, Daniel G|Tang, Laura H|Stadler, Zsofia K|Zhang, Liying
PMID: 27880784
Journal: World J Stem Cells. 2016 Nov 26;8(11):384-395.
Title: Gene expression and pathway analysis of CTNNB1 in cancer and stem cells.
Author: Tanabe, Shihori|Kawabata, Takeshi|Aoyagi, Kazuhiko|Yokozaki, Hiroshi|Sasaki, Hiroki
PMID: 27928465
Journal: Endosc Int Open. 2016 Dec;4(12):E1305-E1310.
Title: Chromoendoscopy in combination with random biopsies does not improve detection of gastric cancer foci in CDH1 mutation positive patients.
Author: Huneburg, Robert|Marwitz, Tim|van Heteren, Peer|Weismuller, Tobias J|Trebicka, Jonel|Adam, Ronja|Aretz, Stefan|Perez Bouza, Alberto|Pantelis, Dimitrios|Kalff, Jorg C|Nattermann, Jacob|Strassburg, Cristian P
PMID: 27995193
Journal: ACG Case Rep J. 2016 Dec 7;3(4):e179.
Title: Prophylactic Total Gastrectomy for Hereditary Diffuse Gastric Cancer.
Author: Shepard, Benjamin|Yoder, Leon|Holmes, Cynthia
PMID: 28008412
Journal: Ann Surg Oncol. 2017 Jan;24(1):184-186.
Title: Creation of a Jejunal Pouch During Laparoscopic Total Gastrectomy and Roux-en-Y Esophagojejunostomy.
Author: Ward, Marc A|Ujiki, Michael B
PMID: 27581611
Journal: Gastroenterology. 2017 Apr;152(5):983-986.e6.
Title: Germline Mutations in PALB2, BRCA1, and RAD51C, Which Regulate DNA Recombination Repair, in Patients With Gastric Cancer.
Author: Sahasrabudhe, Ruta|Lott, Paul|Bohorquez, Mabel|Toal, Ted|Estrada, Ana P|Suarez, John J|Brea-Fernandez, Alejandro|Cameselle-Teijeiro, Jose|Pinto, Carla|Ramos, Irma|Mantilla, Alejandra|Prieto, Rodrigo|Corvalan, Alejandro|Norero, Enrique|Alvarez, Carolina|Ta
PMID: 28024868
Journal: Med Sci Monit. 2017 Feb 4;23:640-648.
Title: MicroRNA-495 Inhibits Gastric Cancer Cell Migration and Invasion Possibly via Targeting High Mobility Group AT-Hook 2 (HMGA2).
Author: Wang, Huashe|Jiang, Zhipeng|Chen, Honglei|Wu, Xiaobin|Xiang, Jun|Peng, Junsheng
PMID: 28159956
Journal: J Transl Med. 2017 May 1;15(1):92.
Title: Transcriptomic profiling and quantitative high-throughput (qHTS) drug screening of CDH1 deficient hereditary diffuse gastric cancer (HDGC) cells identify treatment leads for familial gastric cancer.
Author: Chen, Ina|Mathews-Greiner, Lesley|Li, Dandan|Abisoye-Ogunniyan, Abisola|Ray, Satyajit|Bian, Yansong|Shukla, Vivek|Zhang, Xiaohu|Guha, Raj|Thomas, Craig|Gryder, Berkley|Zacharia, Athina|Beane, Joal D|Ravichandran, Sarangan|Ferrer, Marc|Rudloff, Udo
PMID: 28460635
Journal: Gastroenterology. 2017 Aug;153(2):536-549.e26.
Title: Sporadic Early-Onset Diffuse Gastric Cancers Have High Frequency of Somatic CDH1 Alterations, but Low Frequency of Somatic RHOA Mutations Compared With Late-Onset Cancers.
Author: Cho, Soo Young|Park, Jun Won|Liu, Yang|Park, Young Soo|Kim, Ju Hee|Yang, Hanna|Um, Hyejin|Ko, Woo Ri|Lee, Byung Il|Kwon, Sun Young|Ryu, Seung Wan|Kwon, Chae Hwa|Park, Do Youn|Lee, Jae-Hyuk|Lee, Sang Il|Song, Kyu Sang|Hur, Hoon|Han, Sang-Uk|Chang, Heekyung
PMID: 28522256
Journal: Asian Pac J Cancer Prev. 2017 Jun 25;18(6):1561-1565.
Title: The -160 (C>A) CDH1 Gene Promoter Polymorphism and Its Relationship with Survival of Patients with Gastric Cancer in Kurdistan
Author: Menbari, Mohammad Nazir|Nasseri, Sherko|Menbari, Neda|Mehdiabadi, Ramin|Alipur, Yousef|Roshani, Daem
PMID: 28669168
Journal: Mediators Inflamm. 2017;2017:5432818.
Title: Role of ARPC2 in Human Gastric Cancer.
Author: Zhang, Jun|Liu, Yi|Yu, Chang-Jun|Dai, Fu|Xiong, Jie|Li, Hong-Jun|Wu, Zheng-Sheng|Ding, Rui|Wang, Hong
PMID: 28694563
Journal: Breast Cancer Res Treat. 2017 Nov;166(1):315-319.
Title: Hereditary diffuse gastric cancer and lynch syndromes in a BRCA1/2 negative breast cancer patient.
Author: Njoroge, Scolastica W|Burgess, Kelly R|Cobleigh, Melody A|Alnajar, Hussein H|Gattuso, Paolo|Usha, Lydia
PMID: 28702897
Journal: Tumour Biol. 2017 Jul;39(7):1010428317718404.
Title: EMP3 is induced by TWIST1/2 and regulates epithelial-to-mesenchymal transition of gastric cancer cells.
Author: Han, Ming|Xu, Wanpeng
PMID: 28718375
Journal: Am J Cancer Res. 2017 Jul 1;7(7):1540-1553. eCollection 2017.
Title: Genomic alterations in advanced gastric cancer endoscopic biopsy samples using targeted next-generation sequencing.
Author: Ge, Sai|Li, Beifang|Li, Yanyan|Li, Zhongwu|Liu, Zhentao|Chen, Zuhua|Wu, Jian|Gao, Jing|Shen, Lin
PMID: 28744403
Journal: Cancer Res. 2017 Oct 1;77(19):5349-5359.
Title: Oncogenic KRAS and p53 Loss Drive Gastric Tumorigenesis in Mice That Can Be Attenuated by E-Cadherin Expression.
Author: Till, Jacob E|Yoon, Changhwan|Kim, Bang-Jin|Roby, Kerry|Addai, Prince|Jonokuchi, Evan|Tang, Laura H|Yoon, Sam S|Ryeom, Sandra
PMID: 28760854
Journal: Eur J Hum Genet. 2017 Nov;25(11):1246-1252.
Title: Unraveling genetic predisposition to familial or early onset gastric cancer using germline whole-exome sequencing.
Author: Vogelaar, Ingrid P|van der Post, Rachel S|van Krieken, J Han Jm|Spruijt, Liesbeth|van Zelst-Stams, Wendy Ag|Kets, C Marleen|Lubinski, Jan|Jakubowska, Anna|Teodorczyk, Urszula|Aalfs, Cora M|van Hest, Liselotte P|Pinheiro, Hugo|Oliveira, Carla|Jhangiani, Sh
PMID: 28875981
Journal: Mol Ther Nucleic Acids. 2017 Sep 15;8:291-299.
Title: LncRNA TRERNA1 Function as an Enhancer of SNAI1 Promotes Gastric Cancer Metastasis by Regulating Epithelial-Mesenchymal Transition.
Author: Wu, Huazhang|Hu, Ying|Liu, Xiufang|Song, Wei|Gong, Pihai|Zhang, Kun|Chen, Zhenxing|Zhou, Menghan|Shen, Xiaohui|Qian, Yanyan|Fan, Hong
PMID: 28918030
Journal: Cancer Genet. 2017 Oct;216-217:111-119.
Title: Genetic Gastric Cancer Susceptibility in the International Clinical Cancer Genomics Community Research Network.
Author: Slavin, Thomas|Neuhausen, Susan L|Rybak, Christina|Solomon, Ilana|Nehoray, Bita|Blazer, Kathleen|Niell-Swiller, Mariana|Adamson, Aaron W|Yuan, Yate-Ching|Yang, Kai|Sand, Sharon|Castillo, Danielle|Herzog, Josef|Wu, Xiwei|Tao, Shu|Chavez, Tanya|Woo, Yanghee
PMID: 29025585
Journal: Sci Rep. 2017 Oct 17;7(1):13384.
Title: Effects of long-term aspirin use on molecular alterations in precancerous gastric mucosa in patients with and without gastric cancer.
Author: Michigami, Yuki|Watari, Jiro|Ito, Chiyomi|Hara, Ken|Yamasaki, Takahisa|Kondo, Takashi|Kono, Tomoaki|Tozawa, Katsuyuki|Tomita, Toshihiko|Oshima, Tadayuki|Fukui, Hirokazu|Morimoto, Takeshi|Das, Kiron M|Miwa, Hiroto
PMID: 29042646
Journal: Curr Genomics. 2017 Oct;18(5):408-415.
Title: Implication of Gastric Cancer Molecular Genetic Markers in Surgical Practice.
Author: Nemtsova, Marina V|Strelnikov, Vladimir V|Tanas, Alexander S|Bykov, Igor I|Zaletaev, Dmitry V|Rudenko, Viktoria V|Glukhov, Alexander I|Kchorobrich, Tatiana V|Li, Yi|Tarasov, Vadim V|Barreto, George E|Aliev, Gjumrakch
PMID: 29081696
Journal: Oncotarget. 2017 Sep 8;8(44):77783-77793.
Title: Promoter methylation of tumor-related genes as a potential biomarker using blood samples for gastric cancer detection.
Author: Wen, Jinfeng|Zheng, Tuo|Hu, Kefeng|Zhu, Chunxia|Guo, Lihua|Ye, Guoliang
PMID: 29100425
Journal: Surg Pathol Clin. 2017 Dec;10(4):931-945.
Title: Emerging Concepts in Gastric Neoplasia: Heritable Gastric Cancers and Polyposis Disorders.
Author: van der Post, Rachel S|Carneiro, Fatima
PMID: 29103540
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2017 Nov 25;20(11):1222-1226.
Title: [Current status of hereditary gastrointestinal neoplasms].
Author: He, Yulong
PMID: 29178089
Journal: Int J Mol Sci. 2017 Dec 23;19(1). pii: ijms19010047.
Title: Characterizing Metastatic HER2-Positive Gastric Cancer at the CDH1 Haplotype.
Author: Caggiari, Laura|Miolo, Gianmaria|Buonadonna, Angela|Basile, Debora|Santeufemia, Davide A|Cossu, Antonio|Palmieri, Giuseppe|De Zorzi, Mariangela|Fornasarig, Mara|Alessandrini, Lara|Canzonieri, Vincenzo|Lo Re, Giovanni|Puglisi, Fabio|Steffan, Agostino|Canni
PMID: 29295527
Journal: Gastrointest Endosc. 2018 Feb;87(2):397-404.e2.
Title: Outcomes of screening gastroscopy in first-degree relatives of patients fulfilling hereditary diffuse gastric cancer criteria.
Author: van der Post, Rachel S|van Dieren, Jolanda|Grelack, Anna|Hoogerbrugge, Nicoline|van der Kolk, Lizet E|Snaebjornsson, Petur|Lansdorp-Vogelaar, Iris|van Krieken, J Han|Bisseling, Tanya M|Cats, Annemieke
PMID: 28455161
Journal: Gastrointest Endosc. 2018 Feb;87(2):408-418.
Title: Comparative study of endoscopic surveillance in hereditary diffuse gastric cancer according to CDH1 mutation status.
Author: Mi, Emma Z|Mi, Ella Z|di Pietro, Massimiliano|O'Donovan, Maria|Hardwick, Richard H|Richardson, Susan|Ziauddeen, Hisham|Fletcher, Paul C|Caldas, Carlos|Tischkowitz, Marc|Ragunath, Krish|Fitzgerald, Rebecca C
PMID: 28688938
Journal: Histopathology. 2018 Mar;72(4):556-568.
Title: Gastric poorly cohesive carcinoma: a correlative study of mutational signatures and prognostic significance based on histopathological subtypes.
Author: Kwon, Chae H|Kim, Young K|Lee, Sojeong|Kim, Ahrong|Park, Hye J|Choi, Yuri|Won, Yeo J|Park, Do Y|Lauwers, Gregory Y
PMID: 28873240
Journal: Arch Gynecol Obstet. 2018 Jan;297(1):147-152.
Title: CDH1 mutation screen in a BRCA1/2-negative familial breast-/ovarian cancer cohort.
Author: Stuebs, Frederik|Heidemann, Simone|Caliebe, Almuth|Mundhenke, Christoph|Arnold, Norbert
PMID: 28993866
Journal: Cancer Biol Ther. 2018 Apr 3;19(4):254-259.
Title: A new mutation of the CDH1 gene in a patient with an aggressive signet-ring cell carcinoma of the stomach.
Author: Caggiari, Laura|Miolo, Gianmaria|Canzonieri, Vincenzo|De Zorzi, Mariangela|Alessandrini, Lara|Corona, Giuseppe|Cannizzaro, Renato|Santeufemia, Davide Adriano|Cossu, Antonio|Buonadonna, Angela|De Re, Valli
PMID: 29131691
Journal: Hum Pathol. 2018 Apr;74:64-72.
Title: Histologic and immunohistochemical differences between hereditary and sporadic diffuse gastric carcinoma.
Author: Lee, Hee Eun|Smyrk, Thomas C|Zhang, Lizhi
PMID: 29307626
Journal: J Med Genet. 2018 Oct;55(10):669-674.
Title: Role of germline aberrations affecting CTNNA1, MAP3K6 and MYD88 in gastric cancer susceptibility.
Author: Weren, Robbert D A|van der Post, Rachel S|Vogelaar, Ingrid P|van Krieken, J Han|Spruijt, Liesbeth|Lubinski, Jan|Jakubowska, Anna|Teodorczyk, Urszula|Aalfs, Cora M|van Hest, Liselotte P|Oliveira, Carla|Kamping, Eveline J|Schackert, Hans K|Ranzani, Guglielm
PMID: 29330337
Journal: Br J Surg. 2018 Jan;105(2):e176-e182.
Title: Outcomes after prophylactic gastrectomy for hereditary diffuse gastric cancer.
Author: van der Kaaij, R T|van Kessel, J P|van Dieren, J M|Snaebjornsson, P|Balague, O|van Coevorden, F|van der Kolk, L E|Sikorska, K|Cats, A|van Sandick, J W
PMID: 29341148
Journal: World J Clin Cases. 2018 Jan 16;6(1):1-5.
Title: Hereditary diffuse gastric cancer: One family's story.
Author: Zylberberg, Haley M|Sultan, Keith|Rubin, Steven
PMID: 29376063
Journal: Oncol Lett. 2018 Feb;15(2):2057-2064.
Title: Transcriptome profiling of cancer tissues in Chinese patients with gastric cancer by high-throughput sequencing.
Author: Tian, Peiying|Liang, Chunli
PMID: 29434905
Journal: J Vis Exp. 2018 Feb 5;(132).
Title: Detection of a CDH1 Rare Transcript Variant in Fresh-frozen Gastric Cancer Tissues by Chip-based Digital PCR.
Author: Molinari, Chiara|Abou Khouzam, Raefa|Salvi, Samanta|Rossi, Tania|Ranzani, Guglielmina Nadia|Calistri, Daniele
PMID: 29443099
Journal: Clin Transl Med. 2018 Feb 22;7(1):7.
Title: Merging perspectives: genotype-directed molecular therapy for hereditary diffuse gastric cancer (HDGC) and E-cadherin-EGFR crosstalk.
Author: Li, Dandan|Lo, Winifred|Rudloff, Udo
PMID: 29468433
Journal: Mol Carcinog. 2018 Jul;57(7):947-954.
Title: Multi-omics analysis identifies pathways and genes involved in diffuse-type gastric carcinogenesis induced by E-cadherin, p53, and Smad4 loss in mice.
Author: Park, Jun Won|Kim, Min-Sik|Voon, Dominic C|Kim, Su-Jin|Bae, Jingi|Mun, Dong-Gi|Ko, Seung-Ik|Kim, Hark K|Lee, Sang-Won|Kim, Dae-Yong
PMID: 29528141
Journal: Chin J Cancer Res. 2018 Feb;30(1):122-130.
Title: Germline mutations in hereditary diffuse gastric cancer.
Author: Zhang, Hao|Feng, Mengmeng|Feng, Yi|Bu, Zhaode|Li, Ziyu|Jia, Shuqin|Ji, Jiafu
PMID: 29545726
Journal: J Gastrointest Cancer. 2018 Mar 26. pii: 10.1007/s12029-018-0082-7.
Title: Novel Variants and Copy Number Variation in CDH1 Gene in Iranian Patients with Sporadic Diffuse Gastric Cancer.
Author: Moridnia, Abbas|Tabatabaiefar, Mohammad Amin|Zeinalian, Mehrdad|Minakari, Mohammad|Kheirollahi, Majid|Moghaddam, Noushin Afshar
PMID: 29577179
Journal: Fam Cancer. 2018 Mar 27. pii: 10.1007/s10689-018-0080-8.
Title: Germline CDH1 mutations are a significant contributor to the high frequency of early-onset diffuse gastric cancer cases in New Zealand Maori.
Author: Hakkaart, Christopher|Ellison-Loschmann, Lis|Day, Robert|Sporle, Andrew|Koea, Jonathan|Harawira, Pauline|Cheng, Soo|Gray, Michelle|Whaanga, Tracey|Pearce, Neil|Guilford, Parry
PMID: 29589180
Journal: Exp Mol Med. 2018 Apr 6;50(4):6.
Title: Identification of genomic aberrations associated with lymph node metastasis in diffuse-type gastric cancer.
Author: Choi, Ji-Hye|Kim, Young-Bae|Ahn, Ji Mi|Kim, Min Jae|Bae, Won Jung|Han, Sang-Uk|Woo, Hyun Goo|Lee, Dakeun
PMID: 29622765
Journal: Gut. 2018 Apr 27. pii: gutjnl-2017-314549.
Title: Human gastric cancer modelling using organoids.
Author: Seidlitz, Therese|Merker, Sebastian R|Rothe, Alexander|Zakrzewski, Falk|von Neubeck, Clare|Grutzmann, Konrad|Sommer, Ulrich|Schweitzer, Christine|Scholch, Sebastian|Uhlemann, Heike|Gaebler, Anne-Marlene|Werner, Kristin|Krause, Mechthild|Baretton, Gustavo
PMID: 29703791
Journal: Ann Surg Oncol. 2018 Jul;25(7):2027-2033.
Title: Rates of TP53 Mutation are Significantly Elevated in African American Patients with Gastric Cancer.
Author: van Beek, Elke J A H|Hernandez, Jonathan M|Goldman, Debra A|Davis, Jeremy L|McLaughlin, Kaitlin|Ripley, R Taylor|Kim, Teresa S|Tang, Laura H|Hechtman, Jaclyn F|Zheng, Jian|Capanu, Marinela|Schultz, Nikolaus|Hyman, David M|Ladanyi, Marc|Berger, Michael F|S
PMID: 29725898
Journal: Cancer Res Treat. 2018 Apr 30. pii: crt.2018.085.
Title: Gastric Mucosal Atrophy Impedes Housekeeping Gene Methylation in Gastric Cancer Patients.
Author: Oh, Jung-Hwan|Rhyu, Mun-Gan|Kim, Suk-Il|Yun, Mi-Ri|Shin, Jung-Ha|Hong, Seung-Jin
PMID: 29747491
Journal: Eur J Hum Genet. 2018 May 16. pii: 10.1038/s41431-018-0173-8.
Title: Clinical and functional characterization of the CDH1 germline variant c.1679C>G in three unrelated families with hereditary diffuse gastric cancer.
Author: Pena-Couso, Laura|Perea, Jose|Melo, Soraia|Mercadillo, Fatima|Figueiredo, Joana|Sanches, Joao Miguel|Sanchez-Ruiz, Antonio|Robles, Luis|Seruca, Raquel|Urioste, Miguel
PMID: 29769627
Journal: Int J Mol Med. 2018 Aug;42(2):713-725.
Title: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review).
Author: Katoh, Masaru
PMID: 29786110
Journal: Mol Cells. 2018 Jun;41(6):591-602.
Title: Validation of Neurotensin Receptor 1 as a Therapeutic Target for Gastric Cancer.
Author: Akter, Hafeza|Yoon, Jung Hwan|Yoo, Young Sook|Kang, Min-Jung
PMID: 29794962
Journal: Cold Spring Harb Mol Case Stud. 2018 Aug 1;4(4). pii: mcs.a003012.
Title: A novel de novo CDH1 germline variant aids in the classification of carboxy-terminal E-cadherin alterations predicted to escape nonsense-mediated mRNA decay.
Author: Krempely, Kate|Karam, Rachid
PMID: 29798843
Journal: BMC Mol Biol. 2018 Jun 7;19(1):6.
Title: Targeting miR-9 in gastric cancer cells using locked nucleic acid oligonucleotides.
Author: Lima, Joana Filipa|Carvalho, Joana|Pinto-Ribeiro, Ines|Almeida, Carina|Wengel, Jesper|Cerqueira, Laura|Figueiredo, Ceu|Oliveira, Carla|Azevedo, Nuno Filipe
PMID: 29879907
Journal: Anticancer Res. 2018 Jul;38(7):3871-3877.
Title: Polymorphisms in TWIST1 and ZEB1 Are Associated with Prognosis of Gastric Cancer Patients.
Author: Romero, Sandra|Musleh, Maher|Bustamante, Marco|Stambuk, Juan|Pisano, Raul|Lanzarini, Enrique|Chiong, Hector|Rojas, Jorge|Castro, V Gonzalo|Jara, Lilian|Berger, Zoltan|Gonzalez-Hormazabal, Patricio
PMID: 29970507
Journal: Cancer Genomics Proteomics. 2018 Jul-Aug;15(4):313-320.
Title: Overexpression of FGFR1 Promotes Peritoneal Dissemination Via Epithelial-to-Mesenchymal Transition in Gastric Cancer.
Author: Shimizu, Dai|Saito, Tomoko|Ito, Shuhei|Masuda, Takaaki|Kurashige, Junji|Kuroda, Yosuke|Eguchi, Hidetoshi|Kodera, Yasuhiro|Mimori, Koshi
PMID: 29976636
Journal: Kaohsiung J Med Sci. 2018 Jul;34(7):377-384.
Title: MiR-217 is involved in the carcinogenesis of gastric cancer by down-regulating CDH1 expression.
Author: Li, Wei|Gao, Yu-Qiang
PMID: 30063010
Journal: Gastric Cancer. 2018 Jul 31. pii: 10.1007/s10120-018-0859-1.
Title: E-cadherin-deficient cells have synthetic lethal vulnerabilities in plasma membrane organisation, dynamics and function.
Author: Godwin, Tanis D|Kelly, S Thomas|Brew, Tom P|Bougen-Zhukov, Nicola M|Single, Andrew B|Chen, Augustine|Stylianou, Cassie E|Harris, Lawrence D|Currie, Sophie K|Telford, Bryony J|Beetham, Henry G|Evans, Gary B|Black, Michael A|Guilford, Parry J
PMID: 30066183
Journal: Zentralbl Chir. 2018 Aug 1.
Title: [Outcomes after Prophylactic Total Gastrectomy for Hereditary Diffuse Gastric Cancer].
Author: Pantelis, Dimitrios|Lingohr, Philipp|Hueneburg, Robert|Spier, Isabel|Vilz, Tim|Lau, Jan F|Nattermann, Jacob|Aretz, Stefan|Strassburg, Christian P|Kalff, Jorg C
PMID: 30068014
Journal: Cell. 2018 Aug 9;174(4):856-869.e17.
Title: Divergent Routes toward Wnt and R-spondin Niche Independency during Human Gastric Carcinogenesis.
Author: Nanki, Kosaku|Toshimitsu, Kohta|Takano, Ai|Fujii, Masayuki|Shimokawa, Mariko|Ohta, Yuki|Matano, Mami|Seino, Takashi|Nishikori, Shingo|Ishikawa, Keiko|Kawasaki, Kenta|Togasaki, Kazuhiro|Takahashi, Sirirat|Sukawa, Yasutaka|Ishida, Hiroki|Sugimoto, Shinya|Ka
PMID: 30096312
Journal: Cancer Discov. 2018 Aug 17. pii: 2159-8290.CD-RW2018-140.
Title: Gastric Cancer Organoids Reveal a Wnt Inhibitor Sensitive Subset.
Author:
PMID: 30120113
Journal: World J Surg Oncol. 2018 Aug 22;16(1):174.
Title: Prediction of key genes and pathways involved in trastuzumab-resistant gastric cancer.
Author: Yu, Chaoran|Xue, Pei|Zhang, Luyang|Pan, Ruijun|Cai, Zhenhao|He, Zirui|Sun, Jing|Zheng, Minhua
PMID: 30134903
Journal: Surgery. 2018 Oct;164(4):754-759.
Title: Early genetic counseling and detection of CDH1 mutation in asymptomatic carriers improves survival in hereditary diffuse gastric cancer.
Author: Moslim, Maitham A|Heald, Brandie|Tu, Chao|Burke, Carol A|Walsh, R Matthew
PMID: 30145018
Journal: J Pathol. 2018 Aug 31.
Title: Three types of metaplasia models through Kras activation, Pten deletion, or Cdh1 deletion in the gastric epithelium.
Author: Kinoshita, Hiroto|Hayakawa, Yoku|Konishi, Mitsuru|Hata, Masahiro|Tsuboi, Mayo|Hayata, Yuki|Hikiba, Yohko|Ihara, Sozaburo|Nakagawa, Hayato|Ikenoue, Tsuneo|Ushiku, Tetsuo|Fukayama, Masashi|Hirata, Yoshihiro|Koike, Kazuhiko
PMID: 30168144
Journal: Nat Commun. 2018 Oct 25;9(1):4439.
Title: RhoGAP domain-containing fusions and PPAPDC1A fusions are recurrent and prognostic in diffuse gastric cancer.
Author: Yang, Hanna|Hong, Dongwan|Cho, Soo Young|Park, Young Soo|Ko, Woo Ri|Kim, Ju Hee|Hur, Hoon|Lee, Jongkeun|Kim, Su-Jin|Kwon, Sun Young|Lee, Jae-Hyuk|Park, Do Youn|Song, Kyu Sang|Chang, Heekyung|Ryu, Min-Hee|Cho, Kye Soo|Kang, Jeong Won|Kook, Myeong-Cherl|Thi
PMID: 30361512