Primary Site >> Colorectal Cancer
Gene >> CDC42
| 1. | |||||||||||
| Journal: | Exp Cell Res. 1999 Dec 15;253(2):533-40. | ||||||||||
| Title: | Activated Rac1 selectively up-regulates the expression of integrin alpha6beta4 and induces cell adhesion and membrane ruffles of nonadherent colon cancer Colo201 cells. | ||||||||||
| Author: | Mohri, T|Adachi, Y|Ikehara, S|Hioki, K|Tokunaga, R|Taketani, S | ||||||||||
| PMID: | 10585277 | ||||||||||
| 2. | |||||||||||
| Journal: | J Biol Chem. 2002 Jan 4;277(1):550-8. Epub 2001 Oct 19. | ||||||||||
| Title: | Requirement for PAK4 in the anchorage-independent growth of human cancer cell lines. | ||||||||||
| Author: | Callow, Marinella G|Clairvoyant, Felix|Zhu, Shirley|Schryver, Brian|Whyte, David B|Bischoff, James R|Jallal, Bahija|Smeal, Tod | ||||||||||
| PMID: | 11668177 | ||||||||||
| 3. | |||||||||||
| Journal: | Cancer Lett. 2002 Feb 8;176(1):101-9. | ||||||||||
| Title: | Immunohistochemical analysis of IQGAP1 expression in human colorectal carcinomas: its overexpression in carcinomas and association with invasion fronts. | ||||||||||
| Author: | Nabeshima, Kazuki|Shimao, Yoshiya|Inoue, Teruhiko|Koono, Masashi | ||||||||||
| PMID: | 11790459 | ||||||||||
| 4. | |||||||||||
| Journal: | Mol Cell Neurosci. 2002 Jan;19(1):1-17. | ||||||||||
| Title: | The netrin-1 receptor DCC promotes filopodia formation and cell spreading by activating Cdc42 and Rac1. | ||||||||||
| Author: | Shekarabi, Masoud|Kennedy, Timothy E | ||||||||||
| PMID: | 11817894 | ||||||||||
| 5. | |||||||||||
| Journal: | J Biol Chem. 2002 Apr 26;277(17):15207-14. Epub 2002 Feb 13. | ||||||||||
| Title: | Rac1 and Cdc42 but not RhoA or Rho kinase activities are required for neurite outgrowth induced by the Netrin-1 receptor DCC (deleted in colorectal cancer) in N1E-115 neuroblastoma cells. | ||||||||||
| Author: | Li, Xiaodong|Saint-Cyr-Proulx, Etienne|Aktories, Klaus|Lamarche-Vane, Nathalie | ||||||||||
| PMID: | 11844789 | ||||||||||
| 6. | |||||||||||
| Journal: | Int J Oncol. 2002 Apr;20(4):777-83. | ||||||||||
| Title: | Expression of WRCH1 in human cancer and down-regulation of WRCH1 by beta-estradiol in MCF-7 cells. | ||||||||||
| Author: | Kirikoshi, Hiroyuki|Katoh, Masaru | ||||||||||
| PMID: | 11894124 | ||||||||||
| 7. | |||||||||||
| Journal: | Int J Oncol. 2002 May;20(5):977-82. | ||||||||||
| Title: | Molecular cloning and characterization of WRCH2 on human chromosome 15q15. | ||||||||||
| Author: | Katoh, Masaru | ||||||||||
| PMID: | 11956592 | ||||||||||
| 8. | |||||||||||
| Journal: | Virchows Arch. 2002 Aug;441(2):124-32. Epub 2002 Feb 19. | ||||||||||
| Title: | Complex formation of IQGAP1 with E-cadherin/catenin during cohort migration of carcinoma cells. Its possible association with localized release from cell-cell adhesion. | ||||||||||
| Author: | Shimao, Yoshiya|Nabeshima, Kazuki|Inoue, Teruhiko|Koono, Masashi | ||||||||||
| PMID: | 12189501 | ||||||||||
| 9. | |||||||||||
| Journal: | EMBO J. 2003 Nov 17;22(22):6161-73. | ||||||||||
| Title: | Beta-casein-derived peptides, produced by bacteria, stimulate cancer cell invasion and motility. | ||||||||||
| Author: | Oliveira, Maria Jose|Van Damme, Jozef|Lauwaet, Tineke|De Corte, Veerle|De Bruyne, Georges|Verschraegen, Gerda|Vaneechoutte, Mario|Goethals, Marc|Ahmadian, Mohammad Reza|Muller, Oliver|Vandekerckhove, Joel|Mareel, Marc|Leroy, Ancy | ||||||||||
| PMID: | 14609961 | ||||||||||
| 10. | |||||||||||
| Journal: | Zhonghua Wai Ke Za Zhi. 2004 Jun 7;42(11):668-71. | ||||||||||
| Title: | [Proteome study of colorectal cancer genesis and hepatic metastasis]. | ||||||||||
| Author: | An, Ping|Yu, Bo|Li, Shi-Yong|Zhang, Ying-Nan|Cai, Hui-Yun | ||||||||||
| PMID: | 15329256 | ||||||||||
| 11. | |||||||||||
| Journal: | Gene. 2004 Jul 7;336(1):59-71. | ||||||||||
| Title: | ARHGAP8 is a novel member of the RHOGAP family related to ARHGAP1/CDC42GAP/p50RHOGAP: mutation and expression analyses in colorectal and breast cancers. | ||||||||||
| Author: | Johnstone, Cameron N|Castellvi-Bel, Sergi|Chang, Laura M|Bessa, Xavier|Nakagawa, Hiroshi|Harada, Hideki|Sung, Raphael K|Pique, Josep M|Castells, Antoni|Rustgi, Anil K | ||||||||||
| PMID: | 15225876 | ||||||||||
| 12. | |||||||||||
| Journal: | Clin Cancer Res. 2004 May 15;10(10):3448-56. | ||||||||||
| Title: | Pak-1 expression increases with progression of colorectal carcinomas to metastasis. | ||||||||||
| Author: | Carter, Julia H|Douglass, Larry E|Deddens, James A|Colligan, Bruce M|Bhatt, Tejal R|Pemberton, Jackson O|Konicek, Susan|Hom, Joanne|Marshall, Mark|Graff, Jeremy R | ||||||||||
| PMID: | 15161701 | ||||||||||
| 13. | |||||||||||
| Journal: | Mol Carcinog. 2004 Apr;39(4):206-20. | ||||||||||
| Title: | LyGDI functions in cancer metastasis by anchoring Rho proteins to the cell membrane. | ||||||||||
| Author: | Ota, Takahide|Maeda, Masayo|Suto, Shiho|Tatsuka, Masaaki | ||||||||||
| PMID: | 15057873 | ||||||||||
| 14. | |||||||||||
| Journal: | J Biol Chem. 2005 Apr 8;280(14):13538-44. | ||||||||||
| Title: | The pro-inflammatory mediator leukotriene D4 induces phosphatidylinositol 3-kinase and Rac-dependent migration of intestinal epithelial cells. | ||||||||||
| Author: | Paruchuri, Sailaja|Broom, Oliver|Dib, Karim|Sjolander, Anita | ||||||||||
| PMID: | 15657050 | ||||||||||
| 15. | |||||||||||
| Journal: | J Neurosci. 2005 Mar 23;25(12):3132-41. | ||||||||||
| Title: | Deleted in colorectal cancer binding netrin-1 mediates cell substrate adhesion and recruits Cdc42, Rac1, Pak1, and N-WASP into an intracellular signaling complex that promotes growth cone expansion. | ||||||||||
| Author: | Shekarabi, Masoud|Moore, Simon W|Tritsch, Nicolas X|Morris, Stephen J|Bouchard, Jean-Francois|Kennedy, Timothy E | ||||||||||
| PMID: | 15788770 | ||||||||||
| 16. | |||||||||||
| Journal: | Oncogene. 2005 Dec 15;24(56):8240-51. | ||||||||||
| Title: | Commutators of PAR-1 signaling in cancer cell invasion reveal an essential role of the Rho-Rho kinase axis and tumor microenvironment. | ||||||||||
| Author: | Nguyen, Quang-De|De Wever, Olivier|Bruyneel, Erik|Hendrix, An|Xie, Wan-Zhuo|Lombet, Alain|Leibl, Martin|Mareel, Marc|Gieseler, Frank|Bracke, Marc|Gespach, Christian | ||||||||||
| PMID: | 16091733 | ||||||||||
| 17. | |||||||||||
| Journal: | Cancer Res. 2006 Mar 15;66(6):3153-61. | ||||||||||
| Title: | PRL tyrosine phosphatases regulate rho family GTPases to promote invasion and motility. | ||||||||||
| Author: | Fiordalisi, James J|Keller, Patricia J|Cox, Adrienne D | ||||||||||
| PMID: | 16540666 | ||||||||||
| 18. | |||||||||||
| Journal: | Biochim Biophys Acta. 2007 Feb;1773(2):120-30. | ||||||||||
| Title: | Characterization of a 60S complex of the adenomatous polyposis coli tumor suppressor protein. | ||||||||||
| Author: | Mahadevaiyer, Sreekala|Xu, Chong|Gumbiner, Barry M | ||||||||||
| PMID: | 17126424 | ||||||||||
| 19. | |||||||||||
| Journal: | Mol Cell Biol. 2007 Feb;27(4):1380-93. Epub 2006 Dec 4. | ||||||||||
| Title: | Asef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation element. | ||||||||||
| Author: | Hamann, Michael J|Lubking, Casey M|Luchini, Doris N|Billadeau, Daniel D | ||||||||||
| PMID: | 17145773 | ||||||||||
| 20. | |||||||||||
| Journal: | Int J Mol Med. 2007 Mar;19(3):529-33. | ||||||||||
| Title: | Comparative integromics on FZD7 orthologs: conserved binding sites for PU.1, SP1, CCAAT-box and TCF/LEF/SOX transcription factors within 5'-promoter region of mammalian FZD7 orthologs. | ||||||||||
| Author: | Katoh, Masuko|Katoh, Masaru | ||||||||||
| PMID: | 17273804 | ||||||||||
| 21. | |||||||||||
| Journal: | Oncogene. 2007 Dec 6;26(55):7620-267. Epub 2007 Jun 18. | ||||||||||
| Title: | Identification and characterization of Asef2, a guanine-nucleotide exchange factor specific for Rac1 and Cdc42. | ||||||||||
| Author: | Kawasaki, Y|Sagara, M|Shibata, Y|Shirouzu, M|Yokoyama, S|Akiyama, T | ||||||||||
| PMID: | 17599059 | ||||||||||
| 22. | |||||||||||
| Journal: | Nat Struct Mol Biol. 2007 Sep;14(9):814-23. Epub 2007 Aug 19. | ||||||||||
| Title: | Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression. | ||||||||||
| Author: | Mitin, Natalia|Betts, Laurie|Yohe, Marielle E|Der, Channing J|Sondek, John|Rossman, Kent L | ||||||||||
| PMID: | 17704816 | ||||||||||
| 23. | |||||||||||
| Journal: | Cell Signal. 2008 Jan;20(1):83-93. Epub 2007 Sep 11. | ||||||||||
| Title: | Involvement of G proteins of the Rho family in the regulation of Bcl-2-like protein expression and caspase 3 activation by Gastrins. | ||||||||||
| Author: | He, Hong|Yim, Mildred|Liu, Kevin H|Cody, Stephen C|Shulkes, Arthur|Baldwin, Graham S | ||||||||||
| PMID: | 17936584 | ||||||||||
| 24. | |||||||||||
| Journal: | Int J Cancer. 2008 Dec 1;123(11):2543-56. | ||||||||||
| Title: | Leptin promotes motility and invasiveness in human colon cancer cells by activating multiple signal-transduction pathways. | ||||||||||
| Author: | Jaffe, Tamara|Schwartz, Betty | ||||||||||
| PMID: | 18767036 | ||||||||||
| 25. | |||||||||||
| Journal: | Int J Oncol. 2008 Jul;33(1):185-93. | ||||||||||
| Title: | Cdc42 is highly expressed in colorectal adenocarcinoma and downregulates ID4 through an epigenetic mechanism. | ||||||||||
| Author: | Gomez Del Pulgar, Teresa|Valdes-Mora, Fatima|Bandres, Eva|Perez-Palacios, Rosa|Espina, Carolina|Cejas, Paloma|Garcia-Cabezas, Miguel Angel|Nistal, Manuel|Casado, Enrique|Gonzalez-Baron, Manuel|Garcia-Foncillas, Jesus|Lacal, Juan Carlos | ||||||||||
| PMID: | 18575765 | ||||||||||
| 26. | |||||||||||
| Journal: | J Cell Sci. 2008 Sep 1;121(Pt 17):2805-13. | ||||||||||
| Title: | Rac regulates the interaction of fascin with protein kinase C in cell migration. | ||||||||||
| Author: | Parsons, Maddy|Adams, Josephine C | ||||||||||
| PMID: | 18716283 | ||||||||||
| 27. | |||||||||||
| Journal: | Oncogene. 2009 Mar 12;28(10):1357-65. | ||||||||||
| Title: | Asef2 and Neurabin2 cooperatively regulate actin cytoskeletal organization and are involved in HGF-induced cell migration. | ||||||||||
| Author: | Sagara, M|Kawasaki, Y|Iemura, S-i|Natsume, T|Takai, Y|Akiyama, T | ||||||||||
| PMID: | 19151759 | ||||||||||
| 28. | |||||||||||
| Journal: | Int J Cancer. 2009 Aug 1;125(3):548-55. | ||||||||||
| Title: | P21-activated kinase 5 is overexpressed during colorectal cancer progression and regulates colorectal carcinoma cell adhesion and migration. | ||||||||||
| Author: | Gong, Wei|An, Zhengwen|Wang, Yunling|Pan, Xinyan|Fang, Weigang|Jiang, Bo|Zhang, Hongquan | ||||||||||
| PMID: | 19415746 | ||||||||||
| 29. | |||||||||||
| Journal: | J Biol Chem. 2009 Aug 14;284(33):22436-43. | ||||||||||
| Title: | Adenomatous polyposis coli and Asef function downstream of hepatocyte growth factor and phosphatidylinositol 3-kinase. | ||||||||||
| Author: | Kawasaki, Yoshihiro|Tsuji, Shinnosuke|Sagara, Masaki|Echizen, Kanae|Shibata, Yoko|Akiyama, Tetsu | ||||||||||
| PMID: | 19525225 | ||||||||||
| 30. | |||||||||||
| Journal: | Neoplasia. 2009 Jul;11(7):651-61. | ||||||||||
| Title: | CXCR4 regulates the early extravasation of metastatic tumor cells in vivo. | ||||||||||
| Author: | Gassmann, Peter|Haier, Jorg|Schluter, Kerstin|Domikowsky, Britta|Wendel, Claudia|Wiesner, Ulrike|Kubitza, Robert|Engers, Rainer|Schneider, Stephan W|Homey, Bernhard|Muller, Anja | ||||||||||
| PMID: | 19568410 | ||||||||||
| 31. | |||||||||||
| Journal: | Int J Cancer. 2010 Sep 1;127(5):1220-9. | ||||||||||
| Title: | Isoalvaxanthone inhibits colon cancer cell proliferation, migration and invasion through inactivating Rac1 and AP-1. | ||||||||||
| Author: | Wang, Lei|Kuang, Lisha|Pan, Xinhua|Liu, Junchen|Wang, Qian|Du, Bing|Li, Dali|Luo, Jian|Liu, Mingyao|Hou, Aijun|Qian, Min | ||||||||||
| PMID: | 20017136 | ||||||||||
| 32. | |||||||||||
| Journal: | Int J Oncol. 2010 Feb;36(2):427-34. | ||||||||||
| Title: | A kelch family protein Nd1-L functions as a metastasis suppressor in cancer cells via Rho family proteins mediated mechanism. | ||||||||||
| Author: | Ohta, Yoshihito|Fujimura, Lisa|Nishio, Saori|Arima, Masafumi|Sakamoto, Akemi|Shimada, Hideaki|Ochiai, Takenori|Tokuhisa, Takeshi|Hatano, Masahiko | ||||||||||
| PMID: | 20043078 | ||||||||||
| 33. | |||||||||||
| Journal: | J Biol Chem. 2010 Aug 6;285(32):24987-98. | ||||||||||
| Title: | Tuberous sclerosis complex 2 (TSC2) regulates cell migration and polarity through activation of CDC42 and RAC1. | ||||||||||
| Author: | Larson, Yan|Liu, Jianyu|Stevens, Payton D|Li, Xin|Li, Jing|Evers, B Mark|Gao, Tianyan | ||||||||||
| PMID: | 20530489 | ||||||||||
| 34. | |||||||||||
| Journal: | Tumour Biol. 2010 Dec;31(6):575-82. | ||||||||||
| Title: | p21-activated kinase 5 inhibits camptothecin-induced apoptosis in colorectal carcinoma cells. | ||||||||||
| Author: | Wang, Xia|Gong, Wei|Qing, Haitao|Geng, Yan|Wang, Xinying|Zhang, Yongsheng|Peng, Liang|Zhang, Hongquan|Jiang, Bo | ||||||||||
| PMID: | 20567954 | ||||||||||
| 35. | |||||||||||
| Journal: | Int J Cancer. 2011 Mar 15;128(6):1269-79. | ||||||||||
| Title: | miR-137 targets Cdc42 expression, induces cell cycle G1 arrest and inhibits invasion in colorectal cancer cells. | ||||||||||
| Author: | Liu, Ming|Lang, Nan|Qiu, Meng|Xu, Feng|Li, Qiu|Tang, Qiulin|Chen, Ji|Chen, Xi|Zhang, Siyuan|Liu, Zhen|Zhou, Jitao|Zhu, Yajie|Deng, Yu|Zheng, Yi|Bi, Feng | ||||||||||
| PMID: | 20473940 | ||||||||||
| 36. | |||||||||||
| Journal: | Mol Cancer. 2011 Sep 23;10:118. | ||||||||||
| Title: | BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study. | ||||||||||
| Author: | Makrodouli, Eleni|Oikonomou, Eftychia|Koc, Michal|Andera, Ladislav|Sasazuki, Takehiko|Shirasawa, Senji|Pintzas, Alexander | ||||||||||
| PMID: | 21943101 | ||||||||||
| 37. | |||||||||||
| Journal: | Sichuan Da Xue Xue Bao Yi Xue Ban. 2011 Jul;42(4):466-70. | ||||||||||
| Title: | [The effect of small GTPase Cdc42 on the multidrug resistance of oxaliplatin-resistant colon cancer cell lines]. | ||||||||||
| Author: | Li, Nan-Jing|Liu, Zhen|Zhang, You|Yue, Cai-Xia|Wei, Wen|Li, Li-Lan|Tang, Qiu-Lin|Bi, Feng | ||||||||||
| PMID: | 21866627 | ||||||||||
| 38. | |||||||||||
| Journal: | Mol Biol Cell. 2011 Oct;22(19):3734-46. | ||||||||||
| Title: | The activation of ezrin-radixin-moesin proteins is regulated by netrin-1 through Src kinase and RhoA/Rho kinase activities and mediates netrin-1-induced axon outgrowth. | ||||||||||
| Author: | Antoine-Bertrand, Judith|Ghogha, Atefeh|Luangrath, Vilayphone|Bedford, Fiona K|Lamarche-Vane, Nathalie | ||||||||||
| PMID: | 21849478 | ||||||||||
| 39. | |||||||||||
| Journal: | Biochem Pharmacol. 2011 May 15;81(10):1192-200. | ||||||||||
| Title: | Cudratricusxanthone G inhibits human colorectal carcinoma cell invasion by MMP-2 down-regulation through suppressing activator protein-1 activity. | ||||||||||
| Author: | Kuang, Lisha|Wang, Lei|Wang, Qian|Zhao, Qufei|Du, Bing|Li, Dali|Luo, Jian|Liu, Mingyao|Hou, Aijun|Qian, Min | ||||||||||
| PMID: | 21377450 | ||||||||||
| 40. | |||||||||||
| Journal: | PLoS One. 2011 Feb 2;6(2):e16603. | ||||||||||
| Title: | Rho GTPase Cdc42 is a direct interacting partner of Adenomatous Polyposis Coli protein and can alter its cellular localization. | ||||||||||
| Author: | Sudhaharan, Thankiah|Goh, Wah Ing|Sem, Kai Ping|Lim, Kim Buay|Bu, Wenyu|Ahmed, Sohail | ||||||||||
| PMID: | 21311754 | ||||||||||
| 41. | |||||||||||
| Journal: | Cancer Lett. 2011 Feb 28;301(2):151-60. | ||||||||||
| Title: | miR-185 targets RhoA and Cdc42 expression and inhibits the proliferation potential of human colorectal cells. | ||||||||||
| Author: | Liu, Ming|Lang, Nan|Chen, Xiangzhen|Tang, Qiulin|Liu, Surui|Huang, Juan|Zheng, Yi|Bi, Feng | ||||||||||
| PMID: | 21186079 | ||||||||||
| 42. | |||||||||||
| Journal: | PLoS One. 2012;7(11):e48344. | ||||||||||
| Title: | Cooperative anti-invasive effect of Cdc42/Rac1 activation and ROCK inhibition in SW620 colorectal cancer cells with elevated blebbing activity. | ||||||||||
| Author: | de Toledo, Marion|Anguille, Christelle|Roger, Laureline|Roux, Pierre|Gadea, Gilles | ||||||||||
| PMID: | 23144867 | ||||||||||
| 43. | |||||||||||
| Journal: | Cancer Res. 2012 Nov 15;72(22):5900-11. | ||||||||||
| Title: | Inactivation of the Dlc1 gene cooperates with downregulation of p15INK4b and p16Ink4a, leading to neoplastic transformation and poor prognosis in human cancer. | ||||||||||
| Author: | Qian, Xiaolan|Durkin, Marian E|Wang, Dunrui|Tripathi, Brajendra K|Olson, Lyra|Yang, Xu-Yu|Vass, William C|Popescu, Nicholas C|Lowy, Douglas R | ||||||||||
| PMID: | 23010077 | ||||||||||
| 44. | |||||||||||
| Journal: | Tumour Biol. 2012 Aug;33(4):985-94. | ||||||||||
| Title: | PAK1-dependent MAPK pathway activation is required for colorectal cancer cell proliferation. | ||||||||||
| Author: | Qing, Haitao|Gong, Wei|Che, Yufang|Wang, Xinying|Peng, Liang|Liang, Yan|Wang, Weifei|Deng, Qiliang|Zhang, Hongquan|Jiang, Bo | ||||||||||
| PMID: | 22252525 | ||||||||||
| 45. | |||||||||||
| Journal: | BioData Min. 2012 Aug 28;5(1):11. | ||||||||||
| Title: | Murine colon proteome and characterization of the protein pathways. | ||||||||||
| Author: | Magdeldin, Sameh|Yoshida, Yutaka|Li, Huiping|Maeda, Yoshitaka|Yokoyama, Munesuke|Enany, Shymaa|Zhang, Ying|Xu, Bo|Fujinaka, Hidehiko|Yaoita, Eishin|Sasaki, Sei|Yamamoto, Tadashi | ||||||||||
| PMID: | 22929016 | ||||||||||
| 46. | |||||||||||
| Journal: | J Cell Biochem. 2012 Aug;113(8):2549-59. | ||||||||||
| Title: | Rho GTPase signaling in the development of colorectal cancer. | ||||||||||
| Author: | Leve, Fernanda|Morgado-Diaz, Jose A | ||||||||||
| PMID: | 22467564 | ||||||||||
| 47. | |||||||||||
| Journal: | Cell Res. 2012 Feb;22(2):372-86. | ||||||||||
| Title: | Structural basis for the recognition of Asef by adenomatous polyposis coli. | ||||||||||
| Author: | Zhang, Zhenyi|Chen, Leyi|Gao, Lei|Lin, Kui|Zhu, Liang|Lu, Yang|Shi, Xiaoshan|Gao, Yuan|Zhou, Jing|Xu, Ping|Zhang, Jian|Wu, Geng | ||||||||||
| PMID: | 21788986 | ||||||||||
| 48. | |||||||||||
| Journal: | Int J Clin Oncol. 2012 Apr;17(2):137-42. | ||||||||||
| Title: | Clinical significance of Rho GDP dissociation inhibitor 2 in colorectal carcinoma. | ||||||||||
| Author: | Fujita, Akihiko|Shida, Atsuo|Fujioka, Shuichi|Kurihara, Hideaki|Okamoto, Tomoyoshi|Yanaga, Katsuhiko | ||||||||||
| PMID: | 21698524 | ||||||||||
| 49. | |||||||||||
| Journal: | BMC Biol. 2012 Aug 10;10:72. | ||||||||||
| Title: | A novel Rho-dependent pathway that drives interaction of fascin-1 with p-Lin-11/Isl-1/Mec-3 kinase (LIMK) 1/2 to promote fascin-1/actin binding and filopodia stability. | ||||||||||
| Author: | Jayo, Asier|Parsons, Maddy|Adams, Josephine C | ||||||||||
| PMID: | 22883572 | ||||||||||
| 50. | |||||||||||
| Journal: | J Proteome Res. 2013 Apr 5;12(4):1732-42. | ||||||||||
| Title: | Proteogenomic analysis of human colon carcinoma cell lines LIM1215, LIM1899, and LIM2405. | ||||||||||
| Author: | Fanayan, Susan|Smith, Joshua T|Lee, Ling Y|Yan, Fangfei|Snyder, Michael|Hancock, William S|Nice, Edouard | ||||||||||
| PMID: | 23458625 | ||||||||||
| 51. | |||||||||||
| Journal: | Neoplasia. 2013 Nov;15(11):1218-30. | ||||||||||
| Title: | PTEN phosphatase-independent maintenance of glandular morphology in a predictive colorectal cancer model system. | ||||||||||
| Author: | Jagan, Ishaan C|Deevi, Ravi K|Fatehullah, Aliya|Topley, Rebecca|Eves, Joshua|Stevenson, Michael|Loughrey, Maurice|Arthur, Kenneth|Campbell, Frederick Charles | ||||||||||
| PMID: | 24348097 | ||||||||||
| 52. | |||||||||||
| Journal: | J Transl Med. 2013 Nov 27;11:295. | ||||||||||
| Title: | Targeting Cdc42 with the small molecule drug AZA197 suppresses primary colon cancer growth and prolongs survival in a preclinical mouse xenograft model by downregulation of PAK1 activity. | ||||||||||
| Author: | Zins, Karin|Gunawardhana, Sandun|Lucas, Trevor|Abraham, Dietmar|Aharinejad, Seyedhossein | ||||||||||
| PMID: | 24279335 | ||||||||||
| 53. | |||||||||||
| Journal: | PLoS One. 2013 Nov 11;8(11):e80609. | ||||||||||
| Title: | The miR-1-NOTCH3-Asef pathway is important for colorectal tumor cell migration. | ||||||||||
| Author: | Furukawa, Shiori|Kawasaki, Yoshihiro|Miyamoto, Masaya|Hiyoshi, Masaya|Kitayama, Joji|Akiyama, Tetsu | ||||||||||
| PMID: | 24244701 | ||||||||||
| 54. | |||||||||||
| Journal: | Mol Biol Rep. 2013 Dec;40(12):6561-8. | ||||||||||
| Title: | Network cluster analysis of protein-protein interaction network identified biomarker for early onset colorectal cancer. | ||||||||||
| Author: | Luo, Tiancheng|Wu, Shengdi|Shen, Xizhong|Li, Lei | ||||||||||
| PMID: | 24197691 | ||||||||||
| 55. | |||||||||||
| Journal: | J Biol Chem. 2013 Nov 22;288(47):34019-29. | ||||||||||
| Title: | The Cdc42/Rac nucleotide exchange factor protein beta1Pix (Pak-interacting exchange factor) modulates beta-catenin transcriptional activity in colon cancer cells: evidence for direct interaction of beta1PIX with beta-catenin. | ||||||||||
| Author: | Chahdi, Ahmed|Raufman, Jean-Pierre | ||||||||||
| PMID: | 24129564 | ||||||||||
| 56. | |||||||||||
| Journal: | Med Sci Monit Basic Res. 2013 Jul 25;19:201-7. | ||||||||||
| Title: | Activation of Rho GTPase Cdc42 promotes adhesion and invasion in colorectal cancer cells. | ||||||||||
| Author: | Gao, Lei|Bai, Lan|Nan, Qing zhen | ||||||||||
| PMID: | 23884297 | ||||||||||
| 57. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2013 Feb 15;431(3):560-5. | ||||||||||
| Title: | miR-330 regulates the proliferation of colorectal cancer cells by targeting Cdc42. | ||||||||||
| Author: | Li, Yuefeng|Zhu, Xiaolan|Xu, Wenlin|Wang, Dongqing|Yan, Jinchuan | ||||||||||
| PMID: | 23337504 | ||||||||||
| 58. | |||||||||||
| Journal: | Mol Cancer Res. 2013 Feb;11(2):109-21. | ||||||||||
| Title: | Knockdown of PAK4 or PAK1 inhibits the proliferation of mutant KRAS colon cancer cells independently of RAF/MEK/ERK and PI3K/AKT signaling. | ||||||||||
| Author: | Tabusa, Hana|Brooks, Teresa|Massey, Andrew J | ||||||||||
| PMID: | 23233484 | ||||||||||
| 59. | |||||||||||
| Journal: | Mol Cell Biol. 2013 Feb;33(4):739-51. | ||||||||||
| Title: | Tyrosine phosphorylation of the Rho guanine nucleotide exchange factor Trio regulates netrin-1/DCC-mediated cortical axon outgrowth. | ||||||||||
| Author: | DeGeer, Jonathan|Boudeau, Jerome|Schmidt, Susanne|Bedford, Fiona|Lamarche-Vane, Nathalie|Debant, Anne | ||||||||||
| PMID: | 23230270 | ||||||||||
| 60. | |||||||||||
| Journal: | Cancer Lett. 2013 Jan 28;328(2):278-84. | ||||||||||
| Title: | A non-secretory form of FAM3B promotes invasion and metastasis of human colon cancer cells by upregulating Slug expression. | ||||||||||
| Author: | Li, Zongmeng|Mou, Haiwei|Wang, Ting|Xue, Jing|Deng, Bo|Qian, Lihua|Zhou, Ye|Gong, Wanghua|Wang, Ji Ming|Wu, Guohao|Zhou, Cheng-Fu|Fang, Jing|Le, Yingying | ||||||||||
| PMID: | 23059759 | ||||||||||
| 61. | |||||||||||
| Journal: | Oncogene. 2013 Mar 7;32(10):1305-15. | ||||||||||
| Title: | Rescue of glandular dysmorphogenesis in PTEN-deficient colorectal cancer epithelium by PPARgamma-targeted therapy. | ||||||||||
| Author: | Jagan, I|Fatehullah, A|Deevi, R K|Bingham, V|Campbell, F C | ||||||||||
| PMID: | 22543585 | ||||||||||
| 62. | |||||||||||
| Journal: | Cancer Res. 2014 Oct 1;74(19):5480-92. | ||||||||||
| Title: | CDC42 inhibition suppresses progression of incipient intestinal tumors. | ||||||||||
| Author: | Sakamori, Ryotaro|Yu, Shiyan|Zhang, Xiao|Hoffman, Andrew|Sun, Jiaxin|Das, Soumyashree|Vedula, Pavan|Li, Guangxun|Fu, Jiang|Walker, Francesca|Yang, Chung S|Yi, Zheng|Hsu, Wei|Yu, Da-Hai|Shen, Lanlan|Rodriguez, Alexis J|Taketo, Makoto M|Bonder, Edward M|Ver | ||||||||||
| PMID: | 25113996 | ||||||||||
| 63. | |||||||||||
| Journal: | PLoS One. 2014 Nov 7;9(11):e112288. | ||||||||||
| Title: | miR-18a inhibits CDC42 and plays a tumour suppressor role in colorectal cancer cells. | ||||||||||
| Author: | Humphreys, Karen J|McKinnon, Ross A|Michael, Michael Z | ||||||||||
| PMID: | 25379703 | ||||||||||
| 64. | |||||||||||
| Journal: | Dis Markers. 2014;2014:617150. | ||||||||||
| Title: | MicroRNA-224 suppresses colorectal cancer cell migration by targeting Cdc42. | ||||||||||
| Author: | Ke, Tao-Wei|Hsu, Han-Lin|Wu, Yu-Hua|Chen, William Tzu-Liang|Cheng, Ya-Wen|Cheng, Chao-Wen | ||||||||||
| PMID: | 24817781 | ||||||||||
| 65. | |||||||||||
| Journal: | J Mol Neurosci. 2014 Mar;52(3):323-30. | ||||||||||
| Title: | Piezoelectric ceramic (PZT) modulates axonal guidance growth of rat cortical neurons via RhoA, Rac1, and Cdc42 pathways. | ||||||||||
| Author: | Wen, Jianqiang|Liu, Meili | ||||||||||
| PMID: | 24203571 | ||||||||||
| 66. | |||||||||||
| Journal: | Oncogene. 2014 Apr 17;33(16):2123-33. | ||||||||||
| Title: | Macrophages stimulate gastric and colorectal cancer invasion through EGFR Y(1086), c-Src, Erk1/2 and Akt phosphorylation and smallGTPase activity. | ||||||||||
| Author: | Cardoso, A P|Pinto, M L|Pinto, A T|Oliveira, M I|Pinto, M T|Goncalves, R|Relvas, J B|Figueiredo, C|Seruca, R|Mantovani, A|Mareel, M|Barbosa, M A|Oliveira, M J | ||||||||||
| PMID: | 23644655 | ||||||||||
| 67. | |||||||||||
| Journal: | Oncol Rep. 2014 Jan;31(1):505-15. | ||||||||||
| Title: | Effect of StarD13 on colorectal cancer proliferation, motility and invasion. | ||||||||||
| Author: | Nasrallah, Anita|Saykali, Bechara|Al Dimassi, Saleh|Khoury, Nathalie|Hanna, Samer|El-Sibai, Mirvat | ||||||||||
| PMID: | 24253896 | ||||||||||
| 68. | |||||||||||
| Journal: | Cell Cycle. 2015;14(8):1139-47. | ||||||||||
| Title: | Loss of GM130 in breast cancer cells and its effects on cell migration, invasion and polarity. | ||||||||||
| Author: | Baschieri, Francesco|Uetz-von Allmen, Edith|Legler, Daniel F|Farhan, Hesso | ||||||||||
| PMID: | 25892554 | ||||||||||
| 69. | |||||||||||
| Journal: | Sci Rep. 2015 May 20;5:10442. | ||||||||||
| Title: | A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer. | ||||||||||
| Author: | Al-Tassan, Nada A|Whiffin, Nicola|Hosking, Fay J|Palles, Claire|Farrington, Susan M|Dobbins, Sara E|Harris, Rebecca|Gorman, Maggie|Tenesa, Albert|Meyer, Brian F|Wakil, Salma M|Kinnersley, Ben|Campbell, Harry|Martin, Lynn|Smith, Christopher G|Idziaszczyk, | ||||||||||
| PMID: | 25990418 | ||||||||||
| 70. | |||||||||||
| Journal: | Small GTPases. 2015;6(2):104-7. | ||||||||||
| Title: | Endomembrane control of cell polarity: Relevance to cancer. | ||||||||||
| Author: | Baschieri, Francesco|Farhan, Hesso | ||||||||||
| PMID: | 26156751 | ||||||||||
| 71. | |||||||||||
| Journal: | Int J Clin Exp Pathol. 2015 Sep 1;8(9):10534-44. eCollection 2015. | ||||||||||
| Title: | Down-regualtion of miR-106b induces epithelial-mesenchymal transition but suppresses metastatic colonization by targeting Prrx1 in colorectal cancer. | ||||||||||
| Author: | Zheng, Lin|Zhang, Yuqin|Lin, Shuimiao|Sun, Aimin|Chen, Runze|Ding, Yi|Ding, Yanqing | ||||||||||
| PMID: | 26617763 | ||||||||||
| 72. | |||||||||||
| Journal: | Oncotarget. 2016 Aug 2;7(31):50057-50073. | ||||||||||
| Title: | Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/ MMP9 signaling. | ||||||||||
| Author: | Xiao, Bin|Chen, Daxiang|Luo, Shuhong|Hao, Wenbo|Jing, Fangyan|Liu, Tiancai|Wang, Suihai|Geng, Yan|Li, Linhai|Xu, Weiwen|Zhang, Yajie|Liao, Xiaoqing|Zuo, Daming|Wu, Yingsong|Li, Ming|Ma, Qiang | ||||||||||
| PMID: | 27367023 | ||||||||||
| 73. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2016 Dec 7;35(1):191. | ||||||||||
| Title: | srGAP1 mediates the migration inhibition effect of Slit2-Robo1 in colorectal cancer. | ||||||||||
| Author: | Feng, Yuyang|Feng, Lei|Yu, Di|Zou, Jian|Huang, Zhaohui | ||||||||||
| PMID: | 27923383 | ||||||||||
| 74. | |||||||||||
| Journal: | Oncotarget. 2016 Dec 20;7(51):84826-84838. | ||||||||||
| Title: | MiR-384 inhibits human colorectal cancer metastasis by targeting KRAS and CDC42. | ||||||||||
| Author: | Wang, Yong-Xia|Chen, Yan-Ru|Liu, Shan-Shan|Ye, Ya-Ping|Jiao, Hong-Li|Wang, Shu-Yang|Xiao, Zhi-Yuan|Wei, Wen-Ting|Qiu, Jun-Feng|Liang, Li|Liao, Wen-Ting|Ding, Yan-Qing | ||||||||||
| PMID: | 27769041 | ||||||||||
| 75. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):E5481-90. | ||||||||||
| Title: | MYC-nick promotes cell migration by inducing fascin expression and Cdc42 activation. | ||||||||||
| Author: | Anderson, Sarah|Poudel, Kumud Raj|Roh-Johnson, Minna|Brabletz, Thomas|Yu, Ming|Borenstein-Auerbach, Nofit|Grady, William N|Bai, Jihong|Moens, Cecilia B|Eisenman, Robert N|Conacci-Sorrell, Maralice | ||||||||||
| PMID: | 27566402 | ||||||||||
| 76. | |||||||||||
| Journal: | DNA Cell Biol. 2016 Dec;35(12):819-827. | ||||||||||
| Title: | Low Gene Dosage of Cdc42 Is Not Associated with Protein Dysfunction in Patients with Colorectal Cancer. | ||||||||||
| Author: | Gonzalez-Quiroz, Matias|Calderon, Ximena|Oyarzun, Ingrid|Hoepfner, Claudia|Azocar, Andres|Aguirre, Adam|Alvarez, Karin|Quera, Rodrigo|Lopez-Kostner, Francisco|Melendez, Jaime | ||||||||||
| PMID: | 27540769 | ||||||||||
| 77. | |||||||||||
| Journal: | Oncotarget. 2016 Jul 19;7(29):46042-46055. | ||||||||||
| Title: | High-level expression of P21-Cdc/Rac-activated kinase 7 is closely related to metastatic potential and poor prognosis of colon carcinoma. | ||||||||||
| Author: | Li, Chao|Chen, Jian|Wang, Yupeng|Song, Guohe|Xiao, Chao|Yan, Dongwang|Zhong, Lin|Sun, Xing|Wang, Xiaoliang|Yu, Fudong|Yu, Yang|Tang, Huamei|Peng, Zhihai | ||||||||||
| PMID: | 27323857 | ||||||||||
| 78. | |||||||||||
| Journal: | Oncotarget. 2016 Aug 2;7(31):49042-49064. | ||||||||||
| Title: | Vitamin D3 suppresses morphological evolution of the cribriform cancerous phenotype. | ||||||||||
| Author: | Deevi, Ravi K|McClements, Jane|McCloskey, Karen D|Fatehullah, Aliya|Tkocz, Dorota|Javadi, Arman|Higginson, Robyn|Marsh Durban, Victoria|Jansen, Marnix|Clarke, Alan|Loughrey, Maurice B|Campbell, Frederick C | ||||||||||
| PMID: | 27119498 | ||||||||||
| 79. | |||||||||||
| Journal: | Nan Fang Yi Ke Da Xue Xue Bao. 2016 Apr;36(4):514-9. | ||||||||||
| Title: | [Effect of shRNA-mediated CDC42 knockdown on morphology of colorectal cancer cells in vitro]. | ||||||||||
| Author: | He, Li|Ma, Wen-Xia|Zhang, Qing-Ling | ||||||||||
| PMID: | 27113179 | ||||||||||
| 80. | |||||||||||
| Journal: | Biol Cell. 2016 May;108(5):115-26. | ||||||||||
| Title: | Direct measurement of oscillatory RhoA activity in embryonic cortical neurons stimulated with the axon guidance cue netrin-1 using fluorescence resonance energy transfer. | ||||||||||
| Author: | Antoine-Bertrand, Judith|Fu, Min|Lamarche-Vane, Nathalie | ||||||||||
| PMID: | 26787017 | ||||||||||
| 81. | |||||||||||
| Journal: | Environ Toxicol. 2017 Aug;32(8):2041-2052. | ||||||||||
| Title: | Casticin induced apoptotic cell death and altered associated gene expression in human colon cancer colo 205 cells. | ||||||||||
| Author: | Shang, Hung-Sheng|Liu, Jia-You|Lu, Hsu-Feng|Chiang, Han-Sun|Lin, Chia-Hain|Chen, Ann|Lin, Yuh-Feng|Chung, Jing-Gung | ||||||||||
| PMID: | 27862857 | ||||||||||
| 82. | |||||||||||
| Journal: | Oncotarget. 2017 Apr 18;8(16):26755-26770. | ||||||||||
| Title: | Clinical relevance of the transcriptional signature regulated by CDC42 in colorectal cancer. | ||||||||||
| Author: | Valdes-Mora, Fatima|Locke, Warwick J|Bandres, Eva|Gallego-Ortega, David|Cejas, Paloma|Garcia-Cabezas, Miguel Angel|Colino-Sanguino, Yolanda|Feliu, Jaime|Del Pulgar, Teresa Gomez|Lacal, Juan Carlos | ||||||||||
| PMID: | 28460460 | ||||||||||