Literatures

Primary Site >> Colorectal Cancer

Gene >> CDC25C

1.
Journal:	Carcinogenesis. 2000 Jun;21(6):1129-34.
Title:	Diallyl disulfide inhibits p34(cdc2) kinase activity through changes in complex formation and phosphorylation.
Author:	Knowles, L M\|Milner, J A
PMID:	10837000

2.
Journal:	Curr Pharm Des. 2000 Mar;6(4):379-92.
Title:	Cell cycle molecular targets in novel anticancer drug discovery.
Author:	Buolamwini, J K
PMID:	10788588

3.
Journal:	Leuk Lymphoma. 2001 Jul;42(3):517-20.
Title:	Analysis of the CHK2 gene in lymphoid malignancies.
Author:	Tavor, S\|Takeuchi, S\|Tsukasaki, K\|Miller, C W\|Hofmann, W K\|Ikezoe, T\|Said, J W\|Koeffler, H P
PMID:	11699418

4.
Journal:	Lab Invest. 2001 Apr;81(4):465-73.
Title:	Differential expression of cdc25 cell-cycle-activating phosphatases in human colorectal carcinoma.
Author:	Hernandez, S\|Bessa, X\|Bea, S\|Hernandez, L\|Nadal, A\|Mallofre, C\|Muntane, J\|Castells, A\|Fernandez, P L\|Cardesa, A\|Campo, E
PMID:	11304565

5.
Journal:	Oncogene. 2003 Nov 13;22(51):8271-82.
Title:	Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells.
Author:	Agarwal, Chapla\|Singh, Rana P\|Dhanalakshmi, Sivanandhan\|Tyagi, Anil K\|Tecklenburg, Marianne\|Sclafani, Robert A\|Agarwal, Rajesh
PMID:	14614451

6.
Journal:	J Biol Chem. 2004 Jun 11;279(24):25813-22. Epub 2004 Apr 8.
Title:	Sulforaphane-induced G2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25C.
Author:	Singh, Shivendra V\|Herman-Antosiewicz, Anna\|Singh, Ajita V\|Lew, Karen L\|Srivastava, Sanjay K\|Kamath, Ravindra\|Brown, Kevin D\|Zhang, Lin\|Baskaran, Rajasekaran
PMID:	15073169

7.
Journal:	Acta Pharmacol Sin. 2004 Jun;25(6):756-62.
Title:	Abrogation of Chk1-mediated S/G2 checkpoint by UCN-01 enhances ara-C-induced cytotoxicity in human colon cancer cells.
Author:	Shao, Rong-Guang\|Cao, Chun-Xia\|Pommier, Yves
PMID:	15169628

8.
Journal:	Cell Cycle. 2004 Sep;3(9):1177-81. Epub 2004 Sep 13.
Title:	Chk1, but not Chk2, is involved in the cellular response to DNA damaging agents: differential activity in cells expressing or not p53.
Author:	Carrassa, Laura\|Broggini, Massimo\|Erba, Eugenio\|Damia, Giovanna
PMID:	15326376

9.
Journal:	Cell Mol Life Sci. 2005 Oct;62(19-20):2382-9.
Title:	JNK1-dependent antimitotic activity of thiazolidin compounds in human non-small-cell lung and colon cancer cells.
Author:	Teraishi, F\|Wu, S\|Sasaki, J\|Zhang, L\|Davis, J J\|Guo, W\|Dong, F\|Fang, B
PMID:	16179969

10.
Journal:	J Nutr. 2005 Dec;135(12):2884-90.
Title:	Fisetin inhibits the activities of cyclin-dependent kinases leading to cell cycle arrest in HT-29 human colon cancer cells.
Author:	Lu, Xianghua\|Jung, Jae in\|Cho, Han Jin\|Lim, Do Young\|Lee, Hyun Sook\|Chun, Hyang Sook\|Kwon, Dae Young\|Park, Jung Han Yoon
PMID:	16317137

11.
Journal:	Prostate. 2006 Mar 1;66(4):430-8.
Title:	Antitumor activity and downregulation of pro-angiogenic molecules in human prostate cancer cells by a novel thiazolidione compound.
Author:	Teraishi, Fuminori\|Wu, Shuhong\|Inoue, Satoshi\|Zhang, Lidong\|Davis, John J\|Guo, Wei\|Dong, Fengqin\|Fang, Bingliang
PMID:	16302260

12.
Journal:	Naunyn Schmiedebergs Arch Pharmacol. 2006 Dec;374(3):223-33.
Title:	Investigation of anti-tumor mechanisms of K2154: characterization of tubulin isotypes, mitotic arrest and apoptotic machinery.
Author:	Lu, Pin-Hsuan\|Kung, Fan-Lu\|Kuo, Sheng-Chu\|Chueh, Shih-Chieh\|Guh, Jih-Hwa
PMID:	17102938

13.
Journal:	Cancer Res. 2006 Nov 1;66(21):10349-56.
Title:	Low dietary folate initiates intestinal tumors in mice, with altered expression of G2-M checkpoint regulators polo-like kinase 1 and cell division cycle 25c.
Author:	Knock, Erin\|Deng, Liyuan\|Wu, Qing\|Leclerc, Daniel\|Wang, Xiao-ling\|Rozen, Rima
PMID:	17079455

14.
Journal:	Toxicology. 2006 Jun 15;223(3):235-47.
Title:	Toxic and metabolic effect of sodium butyrate on SAS tongue cancer cells: role of cell cycle deregulation and redox changes.
Author:	Jeng, Jiiang-Huei\|Kuo, Mark Yen-Ping\|Lee, Po-Hsuen\|Wang, Ying-Jan\|Lee, Mon-Ying\|Lee, Jang-Jaer\|Lin, Bor-Ru\|Tai, Tseng-Fang\|Chang, Mei-Chi
PMID:	16737765

15.
Journal:	Oncogene. 2006 Oct 26;25(50):6628-36. Epub 2006 May 22.
Title:	Induction of the adenoma-carcinoma progression and Cdc25A-B phosphatases by the trefoil factor TFF1 in human colon epithelial cells.
Author:	Rodrigues, S\|Rodrigue, C M\|Attoub, S\|Flejou, J F\|Bruyneel, E\|Bracke, M\|Emami, S\|Gespach, C
PMID:	16715141

16.
Journal:	Mol Carcinog. 2006 Jul;45(7):461-78.
Title:	Checkpoint kinase 1-mediated phosphorylation of Cdc25C and bad proteins are involved in antitumor effects of loratadine-induced G2/M phase cell-cycle arrest and apoptosis.
Author:	Chen, Jinn-Shiun\|Lin, Shyr-Yi\|Tso, Wei-Ling\|Yeh, Geng-Chang\|Lee, Wen-Sen\|Tseng, How\|Chen, Li-Ching\|Ho, Yuan-Soon
PMID:	16649252

17.
Journal:	Biochem Biophys Res Commun. 2006 Feb 17;340(3):758-66.
Title:	Elevated expression and potential roles of human Sp5, a member of Sp transcription factor family, in human cancers.
Author:	Chen, Yongxin\|Guo, Yingqiu\|Ge, Xijin\|Itoh, Hirotaka\|Watanabe, Akira\|Fujiwara, Takeshi\|Kodama, Tatsuhiko\|Aburatani, Hiroyuki
PMID:	16380080

18.
Journal:	Mol Cancer Ther. 2007 Jan;6(1):318-25.
Title:	Pharmacologic inhibition of CDC25 phosphatases impairs interphase microtubule dynamics and mitotic spindle assembly.
Author:	Cazales, Martine\|Boutros, Rose\|Brezak, Marie-Christine\|Chaumeron, Sophie\|Prevost, Gregoire\|Ducommun, Bernard
PMID:	17237290

19.
Journal:	Cell Cycle. 2007 Dec 15;6(24):3114-31.
Title:	The cyclin-dependent kinase inhibitor seliciclib (R-roscovitine; CYC202) decreases the expression of mitotic control genes and prevents entry into mitosis.
Author:	Whittaker, Steven R\|Te Poele, Robert H\|Chan, Florence\|Linardopoulos, Spiros\|Walton, Michael I\|Garrett, Michelle D\|Workman, Paul
PMID:	18075315

20.
Journal:	Food Chem Toxicol. 2007 Aug;45(8):1356-67. Epub 2007 Jan 24.
Title:	Tubulozole-induced G2/M cell cycle arrest in human colon cancer cells through formation of microtubule polymerization mediated by ERK1/2 and Chk1 kinase activation.
Author:	Chou, Yean-Hwei\|Ho, Yuan-Soon\|Wu, Chi-Chen\|Chai, Chiah-Yang\|Chen, Soul-Chin\|Lee, Chia-Hwa\|Tsai, Pei-Shan\|Wu, Chih-Hsiung
PMID:	17329004

21.
Journal:	Oncol Rep. 2007 Mar;17(3):597-603.
Title:	Lidamycin induces marked G2 cell cycle arrest in human colon carcinoma HT-29 cells through activation of p38 MAPK pathway.
Author:	Liu, Xia\|Bian, Chunjing\|Ren, Kaihuan\|Jin, Haixia\|Li, Baowei\|Shao, Rong-Guang
PMID:	17273739

22.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2008 May;294(5):G1235-44.
Title:	CUGBP2 downregulation by prostaglandin E2 protects colon cancer cells from radiation-induced mitotic catastrophe.
Author:	Natarajan, Gopalan\|Ramalingam, Satish\|Ramachandran, Ilangovan\|May, Randal\|Queimado, Lurdes\|Houchen, Courtney W\|Anant, Shrikant
PMID:	18325984

23.
Journal:	Oncogene. 2008 Jul 31;27(33):4544-56.
Title:	Translation regulatory factor RBM3 is a proto-oncogene that prevents mitotic catastrophe.
Author:	Sureban, S M\|Ramalingam, S\|Natarajan, G\|May, R\|Subramaniam, D\|Bishnupuri, K S\|Morrison, A R\|Dieckgraefe, B K\|Brackett, D J\|Postier, R G\|Houchen, C W\|Anant, S
PMID:	18427544

24.
Journal:	Biochem Pharmacol. 2008 Jul 1;76(1):53-61.
Title:	Oxaliplatin activity in selected and unselected human ovarian and colorectal cancer cell lines.
Author:	Noordhuis, Paul\|Laan, Adri C\|van de Born, Kasper\|Losekoot, Nienke\|Kathmann, Ietje\|Peters, Godefridus J
PMID:	18508032

25.
Journal:	Cell Cycle. 2008 Jul 15;7(14):2234-40. Epub 2008 May 14.
Title:	Moderate variations in CDC25B protein levels modulate the response to DNA damaging agents.
Author:	Aressy, Bernadette\|Bugler, Beatrix\|Valette, Annie\|Biard, Denis\|Ducommun, Bernard
PMID:	18635965

26.
Journal:	Food Chem Toxicol. 2009 Jan;47(1):171-9.
Title:	Diallyl disulfide induces apoptosis in human colon cancer cell line (COLO 205) through the induction of reactive oxygen species, endoplasmic reticulum stress, caspases casade and mitochondrial-dependent pathways.
Author:	Yang, Jai-Sing\|Chen, Guang-Wei\|Hsia, Te-Chun\|Ho, Heng-Chien\|Ho, Chin-Chin\|Lin, Meng-Wei\|Lin, Song-Shei\|Yeh, Ru-Duan\|Ip, Siu-Wan\|Lu, Hsu-Fung\|Chung, Jing-Gung
PMID:	19038304

27.
Journal:	Int J Radiat Biol. 2009 Feb;85(2):167-74.
Title:	1-Methylxanthine enhances the radiosensitivity of tumor cells.
Author:	Youn, Hyewon\|Hee Kook, Yeon\|Oh, Eun-Taex\|Jeong, Seong-Yun\|Kim, Chulhee\|Kyung Choi, Eun\|Uk Lim, Byung\|Park, Heon Joo
PMID:	19280470

28.
Journal:	Cancer Biol Ther. 2009 Aug;8(16):1559-66. Epub 2009 Aug 8.
Title:	Knockdown of Chk1 sensitizes human colon carcinoma HCT116 cells in a p53-dependent manner to lidamycin through abrogation of a G2/M checkpoint and induction of apoptosis.
Author:	Pan, Yu\|Ren, Kai-Huan\|He, Hong-Wei\|Shao, Rong-Guang
PMID:	19502782

29.
Journal:	Cell Cycle. 2009 Oct 1;8(19):3157-64. Epub 2009 Oct 3.
Title:	Hypoxia-mediated regulation of Cdc25A phosphatase by p21 and miR-21.
Author:	de Oliveira, Pierre E Queiroz\|Zhang, Lin\|Wang, Zhenghe\|Lazo, John S
PMID:	19738433

30.
Journal:	PLoS One. 2010 Oct 1;5(10). pii: e13054.
Title:	cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells.
Author:	Shi, Ting\|Mazumdar, Tapati\|Devecchio, Jennifer\|Duan, Zhong-Hui\|Agyeman, Akwasi\|Aziz, Mohammad\|Houghton, Janet A
PMID:	20957031

31.
Journal:	Anticancer Drugs. 2010 Sep;21(8):766-76.
Title:	Evodiamine induces caspase-dependent apoptosis and S phase arrest in human colon lovo cells.
Author:	Zhang, Chun\|Fan, Xia\|Xu, Xiang\|Yang, Xue\|Wang, Xi\|Liang, Hua-Ping
PMID:	20647931

32.
Journal:	Phytother Res. 2010 Dec;24(12):1870-6.
Title:	Gleditsia sinensis thorn extract inhibits human colon cancer cells: the role of ERK1/2, G2/M-phase cell cycle arrest and p53 expression.
Author:	Lee, Se-Jung\|Park, Keerang\|Ha, Sang-Do\|Kim, Wun-Jae\|Moon, Sung-Kwon
PMID:	20564491

33.
Journal:	Cancer Prev Res (Phila). 2010 Jan;3(1):82-91.
Title:	Chemopreventive effects of Frondanol A5, a Cucumaria frondosa extract, against rat colon carcinogenesis and inhibition of human colon cancer cell growth.
Author:	Janakiram, Naveena B\|Mohammed, Altaf\|Zhang, Yuting\|Choi, Chang-In\|Woodward, Carl\|Collin, Peter\|Steele, Vernon E\|Rao, Chinthalapally V
PMID:	20051375

34.
Journal:	Mol Nutr Food Res. 2010 Apr;54(4):559-65.
Title:	Cucurbitacin B induces G2 arrest and apoptosis via a reactive oxygen species-dependent mechanism in human colon adenocarcinoma SW480 cells.
Author:	Yasuda, Shusuke\|Yogosawa, Shingo\|Izutani, Yasuyuki\|Nakamura, Yoshitaka\|Watanabe, Hirotsuna\|Sakai, Toshiyuki
PMID:	19937855

35.
Journal:	Food Chem Toxicol. 2010 Jan;48(1):277-83.
Title:	c-Jun N-terminal kinase 1 is required for cordycepin-mediated induction of G2/M cell-cycle arrest via p21WAF1 expression in human colon cancer cells.
Author:	Lee, Se-Jung\|Moon, Gi-Seong\|Jung, Kyung-Hwan\|Kim, Wun-Jae\|Moon, Sung-Kwon
PMID:	19833164

36.
Journal:	Int J Oncol. 2010 Mar;36(3):743-9.
Title:	Diallylpolysulfides induce growth arrest and apoptosis.
Author:	Busch, Corinna\|Jacob, Claus\|Anwar, Awais\|Burkholz, Torsten\|Aicha Ba, Lalla\|Cerella, Claudia\|Diederich, Marc\|Brandt, Wolfgang\|Wessjohann, Ludger\|Montenarh, Mathias
PMID:	20126995

37.
Journal:	PLoS One. 2011 Jan 25;6(1):e15561.
Title:	Contributions made by CDC25 phosphatases to proliferation of intestinal epithelial stem and progenitor cells.
Author:	Lee, Gwanghee\|Origanti, Sofia\|White, Lynn S\|Sun, Jinwu\|Stappenbeck, Thaddeus S\|Piwnica-Worms, Helen
PMID:	21283624

38.
Journal:	Cell Res. 2011 May;21(5):730-40.
Title:	A diterpenoid derivative 15-oxospiramilactone inhibits Wnt/beta-catenin signaling and colon cancer cell tumorigenesis.
Author:	Wang, Wei\|Liu, Haiyang\|Wang, Sheng\|Hao, Xiaojiang\|Li, Lin
PMID:	21321609

39.
Journal:	Apoptosis. 2011 Aug;16(8):856-67.
Title:	Shogaols at proapoptotic concentrations induce G(2)/M arrest and aberrant mitotic cell death associated with tubulin aggregation.
Author:	Gan, Fei-Fei\|Nagle, Amrita A\|Ang, Xiaohui\|Ho, Olivia Huixian\|Tan, Sock-Hoon\|Yang, Hong\|Chui, Wai-Keung\|Chew, Eng-Hui
PMID:	21598039

40.
Journal:	Int J Oncol. 2012 Jul;41(1):325-30.
Title:	Nitric oxide-donating aspirin induces G2/M phase cell cycle arrest in human cancer cells by regulating phase transition proteins.
Author:	Gao, Li\|Williams, Jennie L
PMID:	22552812

41.
Journal:	Int J Oncol. 2012 Dec;41(6):2057-64.
Title:	Novel dihydrobenzofuro[4,5-b][1,8]naphthyridin-6-one derivative, MHY-449, induces apoptosis and cell cycle arrest in HCT116 human colon cancer cells.
Author:	Hwang, Hye Jung\|Kang, Yong Jung\|Hossain, Mohammad Akbar\|Kim, Dong Hwan\|Jang, Jung Yoon\|Lee, Sun Hwa\|Yoon, Jeong-Hyun\|Moon, Hyung Ryong\|Kim, Hyung Sik\|Chung, Hae Young\|Kim, Nam Deuk
PMID:	23064444

42.
Journal:	Br J Nutr. 2012 Aug;108 Suppl 1:S145-54.
Title:	Non-digestible fraction of beans (Phaseolus vulgaris L.) modulates signalling pathway genes at an early stage of colon cancer in Sprague-Dawley rats.
Author:	Hayde, Vergara-Castaneda\|Ramon, Guevara-Gonzalez\|Lorenzo, Guevara-Olvera\|Dave, Oomah B\|Rosalia, Reynoso-Camacho\|Paul, Wiersma\|Guadalupe, Loarca-Pina
PMID:	22916810

43.
Journal:	Evid Based Complement Alternat Med. 2012;2012:249217.
Title:	Cordyceps militaris Grown on Germinated Soybean Induces G2/M Cell Cycle Arrest through Downregulation of Cyclin B1 and Cdc25c in Human Colon Cancer HT-29 Cells.
Author:	Mollah, Mohammad Lalmoddin\|Park, Dong Ki\|Park, Hye-Jin
PMID:	22474493

44.
Journal:	BMC Gastroenterol. 2012 Jan 23;12:9.
Title:	Luteolin decreases IGF-II production and downregulates insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells.
Author:	Lim, Do Young\|Cho, Han Jin\|Kim, Jongdai\|Nho, Chu Won\|Lee, Ki Won\|Park, Jung Han Yoon
PMID:	22269172

45.
Journal:	Bioorg Med Chem. 2012 Feb 15;20(4):1584-93.
Title:	Coumarin polysulfides inhibit cell growth and induce apoptosis in HCT116 colon cancer cells.
Author:	Saidu, Nathaniel Edward Bennett\|Valente, Sergio\|Bana, Emilie\|Kirsch, Gilbert\|Bagrel, Denyse\|Montenarh, Mathias
PMID:	22264758

46.
Journal:	Cancer Sci. 2013 Aug;104(8):1062-6.
Title:	HY-1 induces G(2)/M cell cycle arrest in human colon cancer cells through the ATR-Chk1-Cdc25C and Weel pathways.
Author:	Zhao, Yu\|Wu, Zhonghua\|Zhang, Yuting\|Zhu, Li
PMID:	23600770

47.
Journal:	J Cancer Prev. 2013 Sep;18(3):257-63.
Title:	Kaempferol Induces Cell Cycle Arrest in HT-29 Human Colon Cancer Cells.
Author:	Cho, Han Jin\|Park, Jung Han Yoon
PMID:	25337553

48.
Journal:	Cell Death Dis. 2014 Feb 20;5:e1073.
Title:	A functional role for Smad7 in sustaining colon cancer cell growth and survival.
Author:	Stolfi, C\|De Simone, V\|Colantoni, A\|Franze, E\|Ribichini, E\|Fantini, M C\|Caruso, R\|Monteleone, I\|Sica, G S\|Sileri, P\|MacDonald, T T\|Pallone, F\|Monteleone, G
PMID:	24556688

49.
Journal:	Cancer Lett. 2014 Dec 28;355(2):297-309.
Title:	SKLB316, a novel small-molecule inhibitor of cell-cycle progression, induces G2/M phase arrest and apoptosis in vitro and inhibits tumor growth in vivo.
Author:	Xia, Yong\|Lei, Qian\|Zhu, Yongxia\|Ye, Tinghong\|Wang, Ningyu\|Li, Guobo\|Shi, Xuanhong\|Liu, Yantong\|Shao, Bin\|Yin, Tao\|Zhao, Lifeng\|Wu, Wenshuang\|Song, Xuejiao\|Xiong, Ying\|Wei, Yuquan\|Yu, Luoting
PMID:	25301449

50.
Journal:	Cancer Biol Ther. 2014 Sep;15(9):1268-79.
Title:	Chk1-induced CCNB1 overexpression promotes cell proliferation and tumor growth in human colorectal cancer.
Author:	Fang, Yifeng\|Yu, Hong\|Liang, Xiao\|Xu, Junfen\|Cai, Xiujun
PMID:	24971465

51.
Journal:	Int J Oncol. 2014 Sep;45(3):995-1010.
Title:	Enhanced anti-colorectal cancer effects of carfilzomib combined with CPT-11 via downregulation of nuclear factor-kappaB in vitro and in vivo.
Author:	Tang, Weiwei\|Su, Guangjian\|Li, Jieyu\|Liao, Jinrong\|Chen, Shuping\|Huang, Chuanzhong\|Liu, Fang\|Chen, Qiang\|Ye, Yunbin
PMID:	24968890

52.
Journal:	PLoS One. 2014 Jun 24;9(6):e99729.
Title:	Activation of JNK contributes to evodiamine-induced apoptosis and G2/M arrest in human colorectal carcinoma cells: a structure-activity study of evodiamine.
Author:	Chien, Chih-Chiang\|Wu, Ming-Shun\|Shen, Shing-Chuan\|Ko, Ching-Huai\|Chen, Chih-Hung\|Yang, Ling-Ling\|Chen, Yen-Chou
PMID:	24959718

53.
Journal:	Chem Biol Interact. 2014 Aug 5;219:1-8.
Title:	Cucurbitacin-I, a natural cell-permeable triterpenoid isolated from Cucurbitaceae, exerts potent anticancer effect in colon cancer.
Author:	Kim, Hyeon Jin\|Park, Jung Han Yoon\|Kim, Jin-Kyung
PMID:	24858077

54.
Journal:	Int J Oncol. 2014 May;44(5):1599-606.
Title:	Apigenin-induced apoptosis is enhanced by inhibition of autophagy formation in HCT116 human colon cancer cells.
Author:	Lee, Yujin\|Sung, Bokyung\|Kang, Yong Jung\|Kim, Dong Hwan\|Jang, Jung-Yoon\|Hwang, Seong Yeon\|Kim, Minjung\|Lim, Hyun Sook\|Yoon, Jeong-Hyun\|Chung, Hae Young\|Kim, Nam Deuk
PMID:	24626522

55.
Journal:	Int J Oncol. 2014 Jan;44(1):256-64.
Title:	A novel hydroxamic acid derivative, MHY218, induces apoptosis and cell cycle arrest through downregulation of NF-kappaB in HCT116 human colon cancer cells.
Author:	Kim, Mi Kyeong\|Kang, Yong Jung\|Kim, Dong Hwan\|Hossain, Mohammad Akbar\|Jang, Jung Yoon\|Lee, Sun Hwa\|Yoon, Jeong-Hyun\|Chun, Pusoon\|Moon, Hyung Ryong\|Kim, Hyung Sik\|Chung, Hae Young\|Kim, Nam Deuk
PMID:	24190633

56.
Journal:	J Nat Med. 2014 Jan;68(1):53-62.
Title:	Berberine inhibits the growth of human colorectal adenocarcinoma in vitro and in vivo.
Author:	Cai, Yuchen\|Xia, Qing\|Luo, Rongzhen\|Huang, Peiyu\|Sun, Yueli\|Shi, Yanxia\|Jiang, Wenqi
PMID:	23604974

57.
Journal:	Neoplasia. 2015 Sep;17(9):704-715.
Title:	Identification of a Selective G1-Phase Benzimidazolone Inhibitor by a Senescence-Targeted Virtual Screen Using Artificial Neural Networks.
Author:	Bilsland, Alan E\|Pugliese, Angelo\|Liu, Yu\|Revie, John\|Burns, Sharon\|McCormick, Carol\|Cairney, Claire J\|Bower, Justin\|Drysdale, Martin\|Narita, Masashi\|Sadaie, Mahito\|Keith, W Nicol
PMID:	26476078

58.
Journal:	Nutr Cancer. 2017 Jan;69(1):44-55.
Title:	Koelreuteria Formosana Extract Induces Growth Inhibition and Cell Death in Human Colon Carcinoma Cells via G2/M Arrest and LC3-II Activation-Dependent Autophagy.
Author:	Horng, Chi-Ting\|Wu, Yueh-Jung\|Chen, Pei-Ni\|Chu, Shu-Chen\|Tsai, Chun-Miao\|Hsieh, Yih-Shou
PMID:	27880045

59.
Journal:	Oncotarget. 2017 Mar 14;8(11):18106-18117.
Title:	3'-hydroxy-4'-methoxy-beta-methyl-beta-nitrostyrene inhibits tumorigenesis in colorectal cancer cells through ROS-mediated DNA damage and mitochondrial dysfunction.
Author:	Tsai, Chun-Hao\|Hung, Amos C\|Chen, Yuan-Yin\|Chiu, Ya-Wen\|Hsieh, Pei-Wen\|Lee, Yi-Chen\|Su, Yu-Han\|Chang, Po-Chih\|Hu, Stephen Chu-Sung\|Yuan, Shyng-Shiou F
PMID:	28178649

60.
Journal:	Oncol Rep. 2017 Sep;38(3):1783-1789.
Title:	MHY451 induces cell cycle arrest and apoptosis by ROS generation in HCT116 human colorectal cancer cells.
Author:	Hwang, Na Lam\|Kang, Yong Jung\|Sung, Bokyung\|Hwang, Seong Yeon\|Jang, Jung Yoon\|Oh, Hye Jin\|Ahn, Yu Ra\|Kim, Do Hyun\|Kim, Su Jeong\|Ullah, Sultan\|Hossain, Mohammad Akbar\|Moon, Hyung Ryong\|Chung, Hae Young\|Kim, Nam Deuk
PMID:	28731136

61.
Journal:	Oncol Rep. 2017 Oct;38(4):2480-2488.
Title:	Knockdown of tripartite motif-59 inhibits the malignant processes in human colorectal cancer cells.
Author:	Wu, Wei\|Chen, Jingdi\|Wu, Jicheng\|Lin, Jun\|Yang, Sheng\|Yu, Honggang
PMID:	28849218

62.
Journal:	Oncotarget. 2017 Sep 15;8(47):82968-82980.
Title:	RRS1 silencing suppresses colorectal cancer cell proliferation and tumorigenesis by inhibiting G2/M progression and angiogenesis.
Author:	Wu, Xin-Lin\|Yang, Zhi-Wen\|He, Li\|Dong, Pei-De\|Hou, Ming-Xing\|Meng, Xing-Kai\|Zhao, Hai-Ping\|Wang, Zhao-Yang\|Wang, Feng\|Baoluri\|Wurenqimuge\|Agudamu\|Jia, Yong-Feng\|Shi, Lin
PMID:	29137316

63.
Journal:	Med Sci Monit. 2018 Mar 9;24:1424-1433.
Title:	Overexpression of Nitrogen Permease Regulator Like-2 (NPRL2) Enhances Sensitivity to Irinotecan (CPT-11) in Colon Cancer Cells by Activating the DNA Damage Checkpoint Pathway.
Author:	Liu, Shasha\|Liu, Bingrong
PMID:	29519997

64.
Journal:	Cell Physiol Biochem. 2018;47(2):680-693.
Title:	Efficacy of the MEK Inhibitor Cobimetinib and its Potential Application to Colorectal Cancer Cells.
Author:	Gong, Shu\|Xu, Dongsheng\|Zhu, Jialin\|Zou, Fangdong\|Peng, Rui
PMID:	29794421

65.
Journal:	Oncol Lett. 2018 Jun;15(6):8237-8244.
Title:	LncRNA BX357664 inhibits cell proliferation and invasion and promotes cell apoptosis in human colorectal cancer cells.
Author:	Liu, Fengjun\|Wang, Xinsheng\|Liu, Haiyan\|Wang, Yang\|Liu, Xiaoqian\|Hao, Xiaochen\|Li, Hongguang
PMID:	29844809

66.
Journal:	Int J Oncol. 2018 Oct;53(4):1667-1680.
Title:	Radiosensitization by irinotecan is attributed to G2/M phase arrest, followed by enhanced apoptosis, probably through the ATM/Chk/Cdc25C/Cdc2 pathway in p53-mutant colorectal cancer cells.
Author:	Wang, Yaqi\|Yang, Lifeng\|Zhang, Jing\|Zhou, Menglong\|Shen, Lijun\|Deng, Weijuan\|Liang, Liping\|Hu, Ran\|Yang, Wang\|Yao, Ye\|Zhang, Hui\|Zhang, Zhen
PMID:	30085332

67.
Journal:	Nat Commun. 2018 Aug 10;9(1):3212.
Title:	Targeting AURKA-CDC25C axis to induce synthetic lethality in ARID1A-deficient colorectal cancer cells.
Author:	Wu, Changjie\|Lyu, Junfang\|Yang, Eun Ju\|Liu, Yifan\|Zhang, Baoyuan\|Shim, Joong Sup
PMID:	30097580