Primary Site >> Liver Cancer
Gene >> CDC25A
| 1. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14961-6. | ||||||||||
| Title: | Transforming growth factor beta targeted inactivation of cyclin E:cyclin-dependent kinase 2 (Cdk2) complexes by inhibition of Cdk2 activating kinase activity. | ||||||||||
| Author: | Nagahara, H|Ezhevsky, S A|Vocero-Akbani, A M|Kaldis, P|Solomon, M J|Dowdy, S F | ||||||||||
| PMID: | 10611320 | ||||||||||
| 2. | |||||||||||
| Journal: | Cell Res. 1999 Mar;9(1):51-9. | ||||||||||
| Title: | Mad-overexpression down regulates the malignant growth and p53 mediated apoptosis in human hepatocellular carcinoma BEL-7404 cells. | ||||||||||
| Author: | Zhao, H|Xu, Y H | ||||||||||
| PMID: | 10321688 | ||||||||||
| 3. | |||||||||||
| Journal: | Cancer Res. 2001 Oct 1;61(19):7211-6. | ||||||||||
| Title: | Involvement of Cdc25A phosphatase in Hep3B hepatoma cell growth inhibition induced by novel K vitamin analogs. | ||||||||||
| Author: | Wang, Z|Southwick, E C|Wang, M|Kar, S|Rosi, K S|Wilcox, C S|Lazo, J S|Carr, B I | ||||||||||
| PMID: | 11585757 | ||||||||||
| 4. | |||||||||||
| Journal: | Clin Cancer Res. 2003 May;9(5):1764-72. | ||||||||||
| Title: | Overexpression of CDC25A phosphatase is associated with hypergrowth activity and poor prognosis of human hepatocellular carcinomas. | ||||||||||
| Author: | Xu, Xundi|Yamamoto, Hirofumi|Sakon, Masato|Yasui, Masayoshi|Ngan, Chew Yee|Fukunaga, Hiroki|Morita, Tetsushi|Ogawa, Minoru|Nagano, Hiroaki|Nakamori, Shoji|Sekimoto, Mitsugu|Matsuura, Nariaki|Monden, Morito | ||||||||||
| PMID: | 12738732 | ||||||||||
| 5. | |||||||||||
| Journal: | J Cell Physiol. 2005 Jun;203(3):510-9. | ||||||||||
| Title: | Hepatocyte growth factor enhances protein phosphatase Cdc25A inhibitor compound 5-induced hepatoma cell growth inhibition via Akt-mediated MAPK pathway. | ||||||||||
| Author: | Wang, Ziqiu|Wang, Meifang|Carr, Brian I | ||||||||||
| PMID: | 15534860 | ||||||||||
| 6. | |||||||||||
| Journal: | Exp Cell Res. 2005 Mar 10;304(1):1-15. | ||||||||||
| Title: | The relative contribution of CHK1 and CHK2 to Adriamycin-induced checkpoint. | ||||||||||
| Author: | Ho, Chui Chui|Siu, Wai Yi|Chow, Jeremy P H|Lau, Anita|Arooz, Talha|Tong, Hoi Yee|Ng, Irene O L|Poon, Randy Y C | ||||||||||
| PMID: | 15707569 | ||||||||||
| 7. | |||||||||||
| Journal: | Mol Cancer Ther. 2006 Jun;5(6):1511-9. | ||||||||||
| Title: | PM-20, a novel inhibitor of Cdc25A, induces extracellular signal-regulated kinase 1/2 phosphorylation and inhibits hepatocellular carcinoma growth in vitro and in vivo. | ||||||||||
| Author: | Kar, Siddhartha|Wang, Meifang|Yao, Wei|Michejda, Christopher J|Carr, Brian I | ||||||||||
| PMID: | 16818510 | ||||||||||
| 8. | |||||||||||
| Journal: | Biochem Pharmacol. 2006 Nov 15;72(10):1217-27. | ||||||||||
| Title: | Fluorinated Cpd 5, a pure arylating K-vitamin derivative, inhibits human hepatoma cell growth by inhibiting Cdc25 and activating MAPK. | ||||||||||
| Author: | Kar, Siddhartha|Wang, Meifang|Ham, Seung Wook|Carr, Brian I | ||||||||||
| PMID: | 16930563 | ||||||||||
| 9. | |||||||||||
| Journal: | Int J Mol Med. 2008 Feb;21(2):145-52. | ||||||||||
| Title: | CDC25A inhibition suppresses the growth and invasion of human hepatocellular carcinoma cells. | ||||||||||
| Author: | Xu, Xundi|Yamamoto, Hirofumi|Liu, Guoxing|Ito, Yasuhiro|Ngan, Chew Yee|Kondo, Motoi|Nagano, Hiroaki|Dono, Keizo|Sekimoto, Mitsugu|Monden, Morito | ||||||||||
| PMID: | 18204780 | ||||||||||
| 10. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2008 Oct;62(5):831-40. | ||||||||||
| Title: | 2-Methoxyestradiol inhibits hepatocellular carcinoma cell growth by inhibiting Cdc25 and inducing cell cycle arrest and apoptosis. | ||||||||||
| Author: | Kar, Siddhartha|Wang, Meifang|Carr, Brian I | ||||||||||
| PMID: | 18246350 | ||||||||||
| 11. | |||||||||||
| Journal: | Clin Cancer Res. 2008 Nov 1;14(21):6813-20. | ||||||||||
| Title: | Aberrant Polo-like kinase 1-Cdc25A pathway in metastatic hepatocellular carcinoma. | ||||||||||
| Author: | Wang, Xiao Qi|Zhu, Yong Qiang|Lui, Karen S|Cai, Qi|Lu, Ping|Poon, Ronnie T | ||||||||||
| PMID: | 18980975 | ||||||||||
| 12. | |||||||||||
| Journal: | Anticancer Agents Med Chem. 2008 Dec;8(8):863-71. | ||||||||||
| Title: | Cdc25A protein phosphatase: a therapeutic target for liver cancer therapies. | ||||||||||
| Author: | Wang, Z|Kar, S|Carr, B I | ||||||||||
| PMID: | 19075569 | ||||||||||
| 13. | |||||||||||
| Journal: | J Sci Food Agric. 2011 Jan 15;91(1):178-85. | ||||||||||
| Title: | Solanum nigrum L. polyphenolic extract inhibits hepatocarcinoma cell growth by inducing G2/M phase arrest and apoptosis. | ||||||||||
| Author: | Wang, Hsueh-Chun|Chung, Pei-Jun|Wu, Cheng-Hsun|Lan, Kuang-Ping|Yang, Mon-Yuan|Wang, Chau-Jong | ||||||||||
| PMID: | 20853273 | ||||||||||
| 14. | |||||||||||
| Journal: | J Asian Nat Prod Res. 2012;14(7):657-64. | ||||||||||
| Title: | Induction of cell cycle arrest by GL331 via triggering an ATM-dependent DNA damage response in HepG2 cells. | ||||||||||
| Author: | Wang, Ya-Jie|Chen, Xiao-Guang|Xiao, Zhi-Yan|Liu, Geng-Tao|Sun, Hua | ||||||||||
| PMID: | 22583615 | ||||||||||
| 15. | |||||||||||
| Journal: | Exp Cell Res. 2012 Oct 1;318(16):1994-2003. | ||||||||||
| Title: | Rock2 regulates Cdc25A through ubiquitin proteasome system in hepatocellular carcinoma cells. | ||||||||||
| Author: | Liu, Tiande|Yu, Xin|Li, Guohui|Yuan, Rongfa|Wang, Qingnuo|Tang, Ping|Wu, Linquan|Liu, Xiuxia|Peng, Xiaogang|Shao, Jianghua | ||||||||||
| PMID: | 22705122 | ||||||||||
| 16. | |||||||||||
| Journal: | Bioorg Med Chem Lett. 2012 Oct 1;22(19):6120-5. | ||||||||||
| Title: | 13,28-Epoxy triterpenoid saponins from Ardisia japonica selectively inhibit proliferation of liver cancer cells without affecting normal liver cells. | ||||||||||
| Author: | Li, Qin|Li, Wei|Hui, Lin-Ping|Zhao, Chen-Yang|He, Lin|Koike, Kazuo | ||||||||||
| PMID: | 22940450 | ||||||||||
| 17. | |||||||||||
| Journal: | Carcinogenesis. 2012 Dec;33(12):2424-31. | ||||||||||
| Title: | Prevention of liver carcinogenesis by amarogentin through modulation of G1/S cell cycle check point and induction of apoptosis. | ||||||||||
| Author: | Pal, Debolina|Sur, Subhayan|Mandal, Suvra|Das, Ashes|Roy, Anup|Das, Sukta|Panda, Chinmay Kumar | ||||||||||
| PMID: | 22948180 | ||||||||||
| 18. | |||||||||||
| Journal: | PLoS One. 2013;8(3):e60155. | ||||||||||
| Title: | The tumor-suppressive miR-497-195 cluster targets multiple cell-cycle regulators in hepatocellular carcinoma. | ||||||||||
| Author: | Furuta, Mayuko|Kozaki, Ken-ichi|Tanimoto, Kousuke|Tanaka, Shinji|Arii, Shigeki|Shimamura, Teppei|Niida, Atsushi|Miyano, Satoru|Inazawa, Johji | ||||||||||
| PMID: | 23544130 | ||||||||||
| 19. | |||||||||||
| Journal: | Am J Pathol. 2013 Dec;183(6):1719-1730. | ||||||||||
| Title: | Hepatic loss of miR-122 predisposes mice to hepatobiliary cyst and hepatocellular carcinoma upon diethylnitrosamine exposure. | ||||||||||
| Author: | Hsu, Shu-Hao|Wang, Bo|Kutay, Huban|Bid, Hemant|Shreve, Julia|Zhang, Xiaoli|Costinean, Stefan|Bratasz, Anna|Houghton, Peter|Ghoshal, Kalpana | ||||||||||
| PMID: | 24113455 | ||||||||||
| 20. | |||||||||||
| Journal: | Biochimie. 2014 Aug;103:118-25. | ||||||||||
| Title: | CCT128930 induces cell cycle arrest, DNA damage, and autophagy independent of Akt inhibition. | ||||||||||
| Author: | Wang, Feng-Ze|Chang, Zheng-Yao|Fei, Hong-Rong|Yang, Ming-Feng|Yang, Xiao-Yi|Sun, Bao-Liang | ||||||||||
| PMID: | 24793486 | ||||||||||
| 21. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2014;15(8):3651-7. | ||||||||||
| Title: | Schedule-dependent effects of kappa-selenocarrageenan in combination with epirubicin on hepatocellular carcinoma. | ||||||||||
| Author: | Ji, Yu-Bin|Ling, Na|Zhou, Xiao-Jun|Mao, Yun-Xiang|Li, Wen-Lan|Chen, Ning | ||||||||||
| PMID: | 24870773 | ||||||||||
| 22. | |||||||||||
| Journal: | Eur J Med Chem. 2014 Jul 23;82:293-307. | ||||||||||
| Title: | Discovery and characterization of novel imidazopyridine derivative CHEQ-2 as a potent CDC25 inhibitor and promising anticancer drug candidate. | ||||||||||
| Author: | Song, Yu'ning|Lin, Xiaoqian|Kang, Dongwei|Li, Xiao|Zhan, Peng|Liu, Xinyong|Zhang, Qingzhu | ||||||||||
| PMID: | 24922544 | ||||||||||
| 23. | |||||||||||
| Journal: | Acta Pharmacol Sin. 2014 Oct;35(10):1311-22. | ||||||||||
| Title: | Telekin suppresses human hepatocellular carcinoma cells in vitro by inducing G2/M phase arrest via the p38 MAPK signaling pathway. | ||||||||||
| Author: | Li, Lin|Zheng, Bei-bei|Ma, Li-sha|Sun, Xiao|Chang, Juan-juan|Xie, Wei-Dong|Li, Xia | ||||||||||
| PMID: | 25176399 | ||||||||||
| 24. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2014;15(20):8623-9. | ||||||||||
| Title: | Silencing of NUF2 inhibits tumor growth and induces apoptosis in human hepatocellular carcinomas. | ||||||||||
| Author: | Liu, Qiang|Dai, She-Jiao|Li, Hong|Dong, Lei|Peng, Yu-Ping | ||||||||||
| PMID: | 25374179 | ||||||||||
| 25. | |||||||||||
| Journal: | BMC Cancer. 2014 Dec 19;14:987. | ||||||||||
| Title: | SC-III3, a novel scopoletin derivative, induces cytotoxicity in hepatocellular cancer cells through oxidative DNA damage and ataxia telangiectasia-mutated nuclear protein kinase activation. | ||||||||||
| Author: | Zhao, Peng|Chen, Li|Li, Lin-Hu|Wei, Zhi-Feng|Tong, Bei|Jia, Yu-Gai|Kong, Ling-Yi|Xia, Yu-Feng|Dai, Yue | ||||||||||
| PMID: | 25527123 | ||||||||||
| 26. | |||||||||||
| Journal: | Chem Res Toxicol. 2015 Nov 16;28(11):2160-9. | ||||||||||
| Title: | Polychlorinated Biphenyl Quinone Metabolite Promotes p53-Dependent DNA Damage Checkpoint Activation, S-Phase Cycle Arrest and Extrinsic Apoptosis in Human Liver Hepatocellular Carcinoma HepG2 Cells. | ||||||||||
| Author: | Song, Xiufang|Li, Lingrui|Shi, Qiong|Lehmler, Hans-Joachim|Fu, Juanli|Su, Chuanyang|Xia, Xiaomin|Song, Erqun|Song, Yang | ||||||||||
| PMID: | 26451628 | ||||||||||
| 27. | |||||||||||
| Journal: | PLoS One. 2015 Apr 24;10(4):e0124266. | ||||||||||
| Title: | MicroRNA let-7c Inhibits Cell Proliferation and Induces Cell Cycle Arrest by Targeting CDC25A in Human Hepatocellular Carcinoma. | ||||||||||
| Author: | Zhu, Xiuming|Wu, Lingjiao|Yao, Jian|Jiang, Han|Wang, Qiangfeng|Yang, Zhijian|Wu, Fusheng | ||||||||||
| PMID: | 25909324 | ||||||||||
| 28. | |||||||||||
| Journal: | Mol Med Rep. 2016 Feb;13(2):1172-8. | ||||||||||
| Title: | Identification of key genes in hepatocellular carcinoma and validation of the candidate gene, cdc25a, using gene set enrichment analysis, meta-analysis and cross-species comparison. | ||||||||||
| Author: | Lu, Xiaoxu|Sun, Wen|Tang, Yanping|Zhu, Lingqun|Li, Yuan|Ou, Chao|Yang, Chun|Su, Jianjia|Luo, Chengpiao|Hu, Yanling|Cao, Ji | ||||||||||
| PMID: | 26647881 | ||||||||||
| 29. | |||||||||||
| Journal: | Cancer Med. 2016 Feb;5(2):370-85. | ||||||||||
| Title: | Mus81 knockdown improves chemosensitivity of hepatocellular carcinoma cells by inducing S-phase arrest and promoting apoptosis through CHK1 pathway. | ||||||||||
| Author: | Wu, Fan|Chen, Wei-Jia|Yan, Lun|Tan, Guo-Qian|Li, Wei-Tao|Zhu, Xuan-Jin|Ge, Xiao-Chuan|Liu, Jian-Wei|Wang, Bai-Lin | ||||||||||
| PMID: | 26714930 | ||||||||||
| 30. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2016;17(8):3881-5. | ||||||||||
| Title: | MiR-675 Promotes the Growth of Hepatocellular Carcinoma Cells Through the Cdc25A Pathway. | ||||||||||
| Author: | Yu, Ya-Qun|Weng, Jun|Li, Shu-Qun|Li, Bo|Lv, Jun | ||||||||||
| PMID: | 27644634 | ||||||||||
| 31. | |||||||||||
| Journal: | Int J Oncol. 2016 Nov;49(5):2046-2054. | ||||||||||
| Title: | The herbal medicine Cyperus amuricus inhibits proliferation of human hepatocellular carcinoma Hep3B cells by inducing apoptosis and arrest at the G0/G1 cell cycle phase. | ||||||||||
| Author: | Pham, Hai Ha Thi|Seong, Yeong-Ae|Oh, Chul-Woong|Kim, Gun-Do | ||||||||||
| PMID: | 27667556 | ||||||||||
| 32. | |||||||||||
| Journal: | Int J Oncol. 2017 Feb;50(2):414-420. | ||||||||||
| Title: | Crude extract and solvent fractions of Calystegia soldanella induce G1 and S phase arrest of the cell cycle in HepG2 cells. | ||||||||||
| Author: | Lee, Jung Im|Kim, In-Hye|Nam, Taek-Jeong | ||||||||||
| PMID: | 28101580 | ||||||||||
| 33. | |||||||||||
| Journal: | Cell Death Dis. 2017 Mar 23;8(3):e2704. | ||||||||||
| Title: | NPAS2 promotes cell survival of hepatocellular carcinoma by transactivating CDC25A. | ||||||||||
| Author: | Yuan, Peng|Li, Jibin|Zhou, Feng|Huang, Qichao|Zhang, Jiansheng|Guo, Xu|Lyu, Zhuomin|Zhang, Hongxin|Xing, Jinliang | ||||||||||
| PMID: | 28333141 | ||||||||||
| 34. | |||||||||||
| Journal: | Sci Rep. 2017 Aug 30;7(1):9989. | ||||||||||
| Title: | XWL-1-48 exerts antitumor activity via targeting topoisomerase II and enhancing degradation of Mdm2 in human hepatocellular carcinoma. | ||||||||||
| Author: | Wang, Yajie|Sun, Hua|Xiao, Zhiyan|Zhang, Dan|Bao, Xiuqi|Wei, Ning | ||||||||||
| PMID: | 28855652 | ||||||||||
| 35. | |||||||||||
| Journal: | Oncol Rep. 2018 Apr;39(4):1975-1983. | ||||||||||
| Title: | Melatonin induces the apoptosis and inhibits the proliferation of human gastric cancer cells via blockade of the AKT/MDM2 pathway. | ||||||||||
| Author: | Song, Jun|Ma, Sai-Jun|Luo, Jian-Hua|Zhang, Hui|Wang, Ri-Xiong|Liu, Hui|Li, Li|Zhang, Zhi-Guang|Zhou, Rui-Xiang | ||||||||||
| PMID: | 29484412 | ||||||||||