Primary Site >> Colorectal Cancer

Gene >> CDC25A

Journal: Exp Cell Res. 1998 May 1;240(2):236-43.
Title: Elevated expression of the cdc25A protein phosphatase in colon cancer.
Author: Dixon, D|Moyana, T|King, M J
PMID: 9596996
Journal: Cancer Res. 2000 Jun 1;60(11):3043-50.
Title: Overexpression of CDC25B phosphatase as a novel marker of poor prognosis of human colorectal carcinoma.
Author: Takemasa, I|Yamamoto, H|Sekimoto, M|Ohue, M|Noura, S|Miyake, Y|Matsumoto, T|Aihara, T|Tomita, N|Tamaki, Y|Sakita, I|Kikkawa, N|Matsuura, N|Shiozaki, H|Monden, M
PMID: 10850455
Journal: J Antibiot (Tokyo). 2000 Oct;53(10):1191-200.
Title: Mechanism of cell cycle arrest caused by histone deacetylase inhibitors in human carcinoma cells.
Author: Kim, Y B|Ki, S W|Yoshida, M|Horinouchi, S
PMID: 11132966
Journal: Lab Invest. 2001 Apr;81(4):465-73.
Title: Differential expression of cdc25 cell-cycle-activating phosphatases in human colorectal carcinoma.
Author: Hernandez, S|Bessa, X|Bea, S|Hernandez, L|Nadal, A|Mallofre, C|Muntane, J|Castells, A|Fernandez, P L|Cardesa, A|Campo, E
PMID: 11304565
Journal: Biochem Pharmacol. 2003 Apr 1;65(7):1053-60.
Title: Resveratrol-induced G2 arrest through the inhibition of CDK7 and p34CDC2 kinases in colon carcinoma HT29 cells.
Author: Liang, Yu-Chih|Tsai, Shu-Huei|Chen, Linda|Lin-Shiau, Shoei-Yn|Lin, Jen-Kun
PMID: 12663041
Journal: Mol Pharmacol. 2003 Aug;64(2):382-94.
Title: Molecular modes of action of artesunate in tumor cell lines.
Author: Efferth, Thomas|Sauerbrey, Axel|Olbrich, Armin|Gebhart, Erich|Rauch, Pia|Weber, H Oliver|Hengstler, Jan G|Halatsch, Marc-Eric|Volm, Manfred|Tew, Kenneth D|Ross, Douglas D|Funk, Jens Oliver
PMID: 12869643
Journal: Mol Pharmacol. 2004 Jul;66(1):153-60.
Title: Enhanced 7-ethyl-10-hydroxycamptothecin (SN-38) lethality by methylselenocysteine is associated with Chk2 phosphorylation at threonine-68 and down-regulation of Cdc6 expression.
Author: Yin, Ming-Biao|Li, Zhan-Rong|Cao, Shousong|Durrani, Farukh A|Azrak, Rami G|Frank, Cheryl|Rustum, Youcef M
PMID: 15213307
Journal: Cell Cycle. 2004 Sep;3(9):1177-81. Epub 2004 Sep 13.
Title: Chk1, but not Chk2, is involved in the cellular response to DNA damaging agents: differential activity in cells expressing or not p53.
Author: Carrassa, Laura|Broggini, Massimo|Erba, Eugenio|Damia, Giovanna
PMID: 15326376
Journal: Cancer Res. 2004 Sep 15;64(18):6588-94.
Title: 5-fluoro-2'-deoxyuridine-induced cdc25A accumulation correlates with premature mitotic entry and clonogenic death in human colon cancer cells.
Author: Parsels, Leslie Anne|Parsels, Joshua David|Tai, Daniel Chung-Ho|Coughlin, Daniel James|Maybaum, Jonathan
PMID: 15374972
Journal: Oncogene. 2006 Oct 26;25(50):6628-36. Epub 2006 May 22.
Title: Induction of the adenoma-carcinoma progression and Cdc25A-B phosphatases by the trefoil factor TFF1 in human colon epithelial cells.
Author: Rodrigues, S|Rodrigue, C M|Attoub, S|Flejou, J F|Bruyneel, E|Bracke, M|Emami, S|Gespach, C
PMID: 16715141
Journal: Biochem Pharmacol. 2007 Mar 15;73(6):760-72.
Title: Excess ribonucleotide reductase R2 subunits coordinate the S phase checkpoint to facilitate DNA damage repair and recovery from replication stress.
Author: Lin, Z Ping|Belcourt, Michael F|Carbone, Rocco|Eaton, Jana S|Penketh, Philip G|Shadel, Gerald S|Cory, Joseph G|Sartorelli, Alan C
PMID: 17188250
Journal: Carcinogenesis. 2008 Jun;29(6):1258-66.
Title: Mesalazine negatively regulates CDC25A protein expression and promotes accumulation of colon cancer cells in S phase.
Author: Stolfi, Carmine|Fina, Daniele|Caruso, Roberta|Caprioli, Flavio|Fantini, Massimo Claudio|Rizzo, Angelamaria|Sarra, Massimiliano|Pallone, Francesco|Monteleone, Giovanni
PMID: 18495657
Journal: J Cell Physiol. 2009 Nov;221(2):350-8.
Title: E2F4 expression is required for cell cycle progression of normal intestinal crypt cells and colorectal cancer cells.
Author: Garneau, Hugo|Paquin, Marie-Christine|Carrier, Julie C|Rivard, Nathalie
PMID: 19562678
Journal: Cancer Res. 2009 Aug 1;69(15):6100-6.
Title: Tumor repressive functions of estrogen receptor beta in SW480 colon cancer cells.
Author: Hartman, Johan|Edvardsson, Karin|Lindberg, Karolina|Zhao, Chunyan|Williams, Cecilia|Strom, Anders|Gustafsson, Jan-Ake
PMID: 19602591
Journal: Cell Cycle. 2009 Oct 1;8(19):3157-64. Epub 2009 Oct 3.
Title: Hypoxia-mediated regulation of Cdc25A phosphatase by p21 and miR-21.
Author: de Oliveira, Pierre E Queiroz|Zhang, Lin|Wang, Zhenghe|Lazo, John S
PMID: 19738433
Journal: Cancer Res. 2009 Oct 15;69(20):8157-65.
Title: microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells.
Author: Wang, Peng|Zou, Fangdong|Zhang, Xiaodong|Li, Hua|Dulak, Austin|Tomko, Robert J Jr|Lazo, John S|Wang, Zhenghe|Zhang, Lin|Yu, Jian
PMID: 19826040
Journal: Cell Cycle. 2010 Feb 1;9(3):450-5. Epub 2010 Feb 3.
Title: NEK11: linking CHK1 and CDC25A in DNA damage checkpoint signaling.
Author: Sorensen, Claus Storgaard|Melixetian, Marina|Klein, Ditte Kjaersgaard|Helin, Kristian
PMID: 20090422
Journal: PLoS One. 2010 Oct 1;5(10). pii: e13054.
Title: cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells.
Author: Shi, Ting|Mazumdar, Tapati|Devecchio, Jennifer|Duan, Zhong-Hui|Agyeman, Akwasi|Aziz, Mohammad|Houghton, Janet A
PMID: 20957031
Journal: Oncogene. 2011 Jan 27;30(4):398-409.
Title: eIF3m expression influences the regulation of tumorigenesis-related genes in human colon cancer.
Author: Goh, S-H|Hong, S-H|Hong, S-H|Lee, B-C|Ju, M-H|Jeong, J-S|Cho, Y-R|Kim, I-H|Lee, Y-S
PMID: 20838379
Journal: PLoS One. 2011 Jan 25;6(1):e15561.
Title: Contributions made by CDC25 phosphatases to proliferation of intestinal epithelial stem and progenitor cells.
Author: Lee, Gwanghee|Origanti, Sofia|White, Lynn S|Sun, Jinwu|Stappenbeck, Thaddeus S|Piwnica-Worms, Helen
PMID: 21283624
Journal: Oncol Rep. 2011 May;25(5):1297-306.
Title: CDC25A, VAV1, TP73, BRCA1 and ZAP70 gene overexpression correlates with radiation response in colorectal cancer.
Author: Huang, Ming-Yii|Wang, Jaw-Yuan|Chang, Hui-Jen|Kuo, Chia-Wei|Tok, Teck-Siang|Lin, Shiu-Ru
PMID: 21344162
Journal: Int J Cancer. 2013 Apr 1;132(7):1537-46.
Title: Expression of the MAP kinase phosphatase DUSP4 is associated with microsatellite instability in colorectal cancer (CRC) and causes increased cell proliferation.
Author: Groschl, Benedikt|Bettstetter, Marcus|Giedl, Christian|Woenckhaus, Matthias|Edmonston, Tina|Hofstadter, Ferdinand|Dietmaier, Wolfgang
PMID: 22965873
Journal: Int J Mol Sci. 2013 Jan 31;14(2):2980-95.
Title: Compound K, a Ginsenoside Metabolite, Inhibits Colon Cancer Growth via Multiple Pathways Including p53-p21 Interactions.
Author: Zhang, Zhiyu|Du, Guang-Jian|Wang, Chong-Zhi|Wen, Xiao-Dong|Calway, Tyler|Li, Zejuan|He, Tong-Chuan|Du, Wei|Bissonnette, Marc|Musch, Mark W|Chang, Eugene B|Yuan, Chun-Su
PMID: 23434653
Journal: Int J Oncol. 2013 Jul;43(1):289-96.
Title: Genistein induces G2/M cell cycle arrest and apoptosis via ATM/p53-dependent pathway in human colon cancer cells.
Author: Zhang, Zhiyu|Wang, Chong-Zhi|Du, Guang-Jian|Qi, Lian-Wen|Calway, Tyler|He, Tong-Chuan|Du, Wei|Yuan, Chun-Su
PMID: 23686257
Journal: Genes Nutr. 2014 Jan;9(1):359.
Title: The fermented non-digestible fraction of common bean (Phaseolus vulgaris L.) triggers cell cycle arrest and apoptosis in human colon adenocarcinoma cells.
Author: Cruz-Bravo, R K|Guevara-Gonzalez, R G|Ramos-Gomez, M|Oomah, B D|Wiersma, P|Campos-Vega, R|Loarca-Pina, G
PMID: 24293398
Journal: Cell Death Dis. 2014 Feb 20;5:e1073.
Title: A functional role for Smad7 in sustaining colon cancer cell growth and survival.
Author: Stolfi, C|De Simone, V|Colantoni, A|Franze, E|Ribichini, E|Fantini, M C|Caruso, R|Monteleone, I|Sica, G S|Sileri, P|MacDonald, T T|Pallone, F|Monteleone, G
PMID: 24556688
Journal: Am J Chin Med. 2015;43(4):743-56.
Title: Anti-Colon Cancer Effects of 6-Shogaol Through G2/M Cell Cycle Arrest by p53/p21-cdc2/cdc25A Crosstalk.
Author: Qi, Lian-Wen|Zhang, Zhiyu|Zhang, Chun-Feng|Anderson, Samantha|Liu, Qun|Yuan, Chun-Su|Wang, Chong-Zhi
PMID: 26119958
Journal: Environ Toxicol. 2016 Aug;31(8):957-69.
Title: Crude extract of Rheum palmatum L. Induces cell cycle arrest S phase and apoptosis through mitochondrial-dependent pathways in U-2 OS human osteosarcoma cells.
Author: Lin, Chin-Chung|Lee, Ming-Huei|Lin, Ju-Hwa|Lin, Meng-Liang|Chueh, Fu-Shin|Yu, Chien-Chih|Lin, Jing-Pin|Chou, Yu-Cheng|Hsu, Shu-Chun|Chung, Jing-Gung
PMID: 25689151
Journal: Cancer Med. 2016 Feb;5(2):370-85.
Title: Mus81 knockdown improves chemosensitivity of hepatocellular carcinoma cells by inducing S-phase arrest and promoting apoptosis through CHK1 pathway.
Author: Wu, Fan|Chen, Wei-Jia|Yan, Lun|Tan, Guo-Qian|Li, Wei-Tao|Zhu, Xuan-Jin|Ge, Xiao-Chuan|Liu, Jian-Wei|Wang, Bai-Lin
PMID: 26714930
Journal: Oncotarget. 2017 Mar 14;8(11):18106-18117.
Title: 3'-hydroxy-4'-methoxy-beta-methyl-beta-nitrostyrene inhibits tumorigenesis in colorectal cancer cells through ROS-mediated DNA damage and mitochondrial dysfunction.
Author: Tsai, Chun-Hao|Hung, Amos C|Chen, Yuan-Yin|Chiu, Ya-Wen|Hsieh, Pei-Wen|Lee, Yi-Chen|Su, Yu-Han|Chang, Po-Chih|Hu, Stephen Chu-Sung|Yuan, Shyng-Shiou F
PMID: 28178649
Journal: Clin Res Hepatol Gastroenterol. 2017 Oct;41(5):592-601.
Title: Mus81 knockdown sensitizes colon cancer cells to chemotherapeutic drugs by activating CHK1 pathway.
Author: Wu, Fan|Su, Shu-Chao|Tan, Guo-Qian|Yan, Lun|Li, Ting-Yue|Zhang, Hao-Lu|Yu, Ji-Shang|Wang, Bai-Lin
PMID: 28291626
Journal: Oncol Lett. 2018 Apr;15(4):5368-5374.
Title: SIRT6 inhibits colorectal cancer stem cell proliferation by targeting CDC25A.
Author: Liu, Wenguang|Wu, Manwu|Du, Hechun|Shi, Xiaoliang|Zhang, Tao|Li, Jie
PMID: 29552180
Journal: Oncol Lett. 2018 Oct;16(4):4671-4678.
Title: Chaetominine induces cell cycle arrest in human leukemia K562 and colon cancer SW1116 cells.
Author: Yao, Jingyun|Xiao, Jianbo|Wei, Xing|Lu, Yanhua
PMID: 30214601