Primary Site >> Colorectal Cancer
Gene >> CDC25A
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Ref: Elevated expression of the cdc25A protein phosphatase in colon cancer. PMID: 9596996 |
Ref: Overexpression of CDC25B phosphatase as a novel marker of poor prognosis of human colorectal carcinoma. PMID: 10850455 Ref: Mechanism of cell cycle arrest caused by histone deacetylase inhibitors in human carcinoma cells. PMID: 11132966 |
Ref: Differential expression of cdc25 cell-cycle-activating phosphatases in human colorectal carcinoma. PMID: 11304565 |
Ref: Resveratrol-induced G2 arrest through the inhibition of CDK7 and p34CDC2 kinases in colon carcinoma HT29 cells. PMID: 12663041 Ref: Molecular modes of action of artesunate in tumor cell lines. PMID: 12869643 |
Ref: Enhanced 7-ethyl-10-hydroxycamptothecin (SN-38) lethality by methylselenocysteine is associated with Chk2 phosphorylation at threonine-68 and down-regulation of Cdc6 expression. PMID: 15213307 Ref: Chk1, but not Chk2, is involved in the cellular response to DNA damaging agents: differential activity in cells expressing or not p53. PMID: 15326376 Ref: 5-fluoro-2'-deoxyuridine-induced cdc25A accumulation correlates with premature mitotic entry and clonogenic death in human colon cancer cells. PMID: 15374972 |
Ref: Induction of the adenoma-carcinoma progression and Cdc25A-B phosphatases by the trefoil factor TFF1 in human colon epithelial cells. PMID: 16715141 |
Ref: Excess ribonucleotide reductase R2 subunits coordinate the S phase checkpoint to facilitate DNA damage repair and recovery from replication stress. PMID: 17188250 |
Ref: Mesalazine negatively regulates CDC25A protein expression and promotes accumulation of colon cancer cells in S phase. PMID: 18495657 |
Ref: E2F4 expression is required for cell cycle progression of normal intestinal crypt cells and colorectal cancer cells. PMID: 19562678 Ref: Tumor repressive functions of estrogen receptor beta in SW480 colon cancer cells. PMID: 19602591 Ref: Hypoxia-mediated regulation of Cdc25A phosphatase by p21 and miR-21. PMID: 19738433 Ref: microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells. PMID: 19826040 |
Ref: NEK11: linking CHK1 and CDC25A in DNA damage checkpoint signaling. PMID: 20090422 Ref: cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells. PMID: 20957031 |
Ref: eIF3m expression influences the regulation of tumorigenesis-related genes in human colon cancer. PMID: 20838379 Ref: Contributions made by CDC25 phosphatases to proliferation of intestinal epithelial stem and progenitor cells. PMID: 21283624 Ref: CDC25A, VAV1, TP73, BRCA1 and ZAP70 gene overexpression correlates with radiation response in colorectal cancer. PMID: 21344162 |
Ref: Expression of the MAP kinase phosphatase DUSP4 is associated with microsatellite instability in colorectal cancer (CRC) and causes increased cell proliferation. PMID: 22965873 Ref: Compound K, a Ginsenoside Metabolite, Inhibits Colon Cancer Growth via Multiple Pathways Including p53-p21 Interactions. PMID: 23434653 Ref: Genistein induces G2/M cell cycle arrest and apoptosis via ATM/p53-dependent pathway in human colon cancer cells. PMID: 23686257 |
Ref: The fermented non-digestible fraction of common bean (Phaseolus vulgaris L.) triggers cell cycle arrest and apoptosis in human colon adenocarcinoma cells. PMID: 24293398 Ref: A functional role for Smad7 in sustaining colon cancer cell growth and survival. PMID: 24556688 |
Ref: Anti-Colon Cancer Effects of 6-Shogaol Through G2/M Cell Cycle Arrest by p53/p21-cdc2/cdc25A Crosstalk. PMID: 26119958 |
Ref: Crude extract of Rheum palmatum L. Induces cell cycle arrest S phase and apoptosis through mitochondrial-dependent pathways in U-2 OS human osteosarcoma cells. PMID: 25689151 Ref: Mus81 knockdown improves chemosensitivity of hepatocellular carcinoma cells by inducing S-phase arrest and promoting apoptosis through CHK1 pathway. PMID: 26714930 |
Ref: 3'-hydroxy-4'-methoxy-beta-methyl-beta-nitrostyrene inhibits tumorigenesis in colorectal cancer cells through ROS-mediated DNA damage and mitochondrial dysfunction. PMID: 28178649 Ref: Mus81 knockdown sensitizes colon cancer cells to chemotherapeutic drugs by activating CHK1 pathway. PMID: 28291626 |
Ref: SIRT6 inhibits colorectal cancer stem cell proliferation by targeting CDC25A. PMID: 29552180 Ref: Chaetominine induces cell cycle arrest in human leukemia K562 and colon cancer SW1116 cells. PMID: 30214601 |