Primary Site >> Pancreatic Cancer

Gene >> CD44

Journal: Cell. 1991 Apr 5;65(1):13-24.
Title: A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells.
Author: Gunthert, U|Hofmann, M|Rudy, W|Reber, S|Zoller, M|Haussmann, I|Matzku, S|Wenzel, A|Ponta, H|Herrlich, P
PMID: 1707342
Journal: Cancer Res. 1991 Oct 1;51(19):5292-7.
Title: CD44 splice variants confer metastatic behavior in rats: homologous sequences are expressed in human tumor cell lines.
Author: Hofmann, M|Rudy, W|Zoller, M|Tolg, C|Ponta, H|Herrlich, P|Gunthert, U
PMID: 1717145
Journal: Int J Cancer. 1994 Jan 15;56(2):269-74.
Title: The MHC class-II and CD44 molecules are involved in the induction of tumour necrosis factor (TNF) gene expression by human monocytes stimulated with tumour cells.
Author: Zembala, M|Siedlar, M|Ruggiero, I|Wieckiewicz, J|Mytar, B|Mattei, M|Colizzi, V
PMID: 7508890
Journal: Pancreas. 1994 Nov;9(6):748-52.
Title: The significance of CD44 in human pancreatic cancer: I. High expression of CD44 in human pancreatic adenocarcinoma.
Author: Takada, M|Yamamoto, M|Saitoh, Y
PMID: 7531334
Journal: Pancreas. 1994 Nov;9(6):753-7.
Title: The significance of CD44 in human pancreatic cancer: II. The role of CD44 in human pancreatic adenocarcinoma invasion.
Author: Takada, M|Yamamoto, M|Saitoh, Y
PMID: 7531335
Journal: J Cell Sci. 1995 May;108 ( Pt 5):1959-70.
Title: CD44 is the major peanut lectin-binding glycoprotein of human epidermal keratinocytes and plays a role in intercellular adhesion.
Author: Hudson, D L|Sleeman, J|Watt, F M
PMID: 7544799
Journal: Invasion Metastasis. 1995;15(1-2):60-9.
Title: Characterization of human pancreatic adenocarcinoma cell line with high metastatic potential in SCID mice.
Author: Siedlar, M|Stachura, J|Szczepanik, A|Popiela, T|Mattei, M|Vendetti, S|Colizzi, V|Zembala, M
PMID: 7545654
Journal: Cancer Res. 1995 Dec 1;55(23):5499-503.
Title: Differential expression of CD44 splice variants in human pancreatic adenocarcinoma and in normal pancreas.
Author: Gansauge, F|Gansauge, S|Zobywalski, A|Scharnweber, C|Link, K H|Nussler, A K|Beger, H G
PMID: 7585621
Journal: EMBO J. 1996 Aug 1;15(15):4030-9.
Title: Trans-acting factors regulate the expression of CD44 splice variants.
Author: Konig, H|Moll, J|Ponta, H|Herrlich, P
PMID: 8670907
Journal: Cancer Res. 1996 Jul 1;56(13):3134-41.
Title: Hyaluronate-independent metastatic behavior of CD44 variant-expressing pancreatic carcinoma cells.
Author: Sleeman, J P|Arming, S|Moll, J F|Hekele, A|Rudy, W|Sherman, L S|Kreil, G|Ponta, H|Herrlich, P
PMID: 8674073
Journal: J Mol Med (Berl). 1996 May;74(5):253-68.
Title: Adhesion receptors in malignant transformation and dissemination of gastrointestinal tumors.
Author: Streit, M|Schmidt, R|Hilgenfeld, R U|Thiel, E|Kreuser, E D
PMID: 8773262
Journal: Recent Results Cancer Res. 1996;142:19-50.
Title: Adhesion receptors in malignant transformation and dissemination of gastrointestinal tumors.
Author: Streit, M|Schmidt, R|Hilgenfeld, R U|Thiel, E|Kreuser, E D
PMID: 8893333
Journal: Int J Cancer. 1996 Oct 9;68(2):232-8.
Title: Growth retardation of tumors by adoptive transfer of cytotoxic T lymphocytes reprogrammed by CD44v6-specific scFv:zeta-chimera.
Author: Hekele, A|Dall, P|Moritz, D|Wels, W|Groner, B|Herrlich, P|Ponta, H
PMID: 8900434
Journal: Clin Cancer Res. 1996 Sep;2(9):1607-18.
Title: Differential expression of the hyaluronan receptors CD44 and RHAMM in human pancreatic cancer cells.
Author: Abetamann, V|Kern, H F|Elsasser, H P
PMID: 9816340
Journal: Anticancer Res. 1997 Jan-Feb;17(1A):215-9.
Title: Expression of CD44 in duct cell carcinomas and in intraductal neoplasms of the pancreas.
Author: Satoh, K|Shimosegawa, T|Koizumi, M|Toyota, T
PMID: 9066654
Journal: Cancer. 1997 Nov 1;80(9):1733-9.
Title: Low serum levels of soluble CD44 variant 6 are significantly associated with poor prognosis in patients with pancreatic carcinoma.
Author: Gansauge, F|Gansauge, S|Rau, B|Scheiblich, A|Poch, B|Schoenberg, M H|Beger, H G
PMID: 9351541
Journal: Yale J Biol Med. 1997 Sep-Dec;70(5-6):501-8.
Title: Biochemical diagnosis of neuroendocrine GEP tumor.
Author: Oberg, K
PMID: 9825477
Journal: Int J Oncol. 1997 Jan;10(1):183-8.
Title: Adhesion of human gastric and pancreatic cancer cells to peritoneal mesothelial cells is mediated by CD44 and beta(1) integrin.
Author: Nakashio, T|Narita, T|Akiyama, S|Kasai, Y|Fujiwara, M|Ito, K|Takagi, H|Kanngi, R
PMID: 21533362
Journal: J Surg Oncol. 1998 Feb;67(2):77-84.
Title: Involvement of adhesion molecules in metastasis of SW1990, human pancreatic cancer cells.
Author: Hosono, J|Narita, T|Kimura, N|Sato, M|Nakashio, T|Kasai, Y|Nonami, T|Nakao, A|Takagi, H|Kannagi, R
PMID: 9486777
Journal: Scand J Gastroenterol. 1998 Jan;33(1):82-7.
Title: CD44 splice variants as prognostic markers in colorectal cancer.
Author: Wielenga, V J|van der Voort, R|Mulder, J W|Kruyt, P M|Weidema, W F|Oosting, J|Seldenrijk, C A|van Krimpen, C|Offerhaus, G J|Pals, S T
PMID: 9489913
Journal: Eur J Med Res. 1998 Sep 17;3(9):419-26.
Title: The splice-pattern of CD44 is altered in chronic pancreatitis exhibiting dysplastic changes.
Author: Gansauge, F|Gansauge, S|Schlosser, W|Schmid, R|Adler, G|Beger, H G
PMID: 9737888
Journal: Gan To Kagaku Ryoho. 1998 Nov;25(13):2036-42.
Title: [The prognostic factors of pancreatic cancer--adhesion molecule CD44].
Author: Gotoda, T|Matsumura, Y|Kokawa, A|Kondo, H
PMID: 9838904
Journal: Jpn J Cancer Res. 1998 Oct;89(10):1033-40.
Title: Expression of CD44 variants and its association with survival in pancreatic cancer.
Author: Gotoda, T|Matsumura, Y|Kondo, H|Saitoh, D|Shimada, Y|Kosuge, T|Kanai, Y|Kakizoe, T
PMID: 9849582
Journal: Biochem Biophys Res Commun. 1999 May 10;258(2):395-400.
Title: High levels of ezrin expressed by human pancreatic adenocarcinoma cell lines with high metastatic potential.
Author: Akisawa, N|Nishimori, I|Iwamura, T|Onishi, S|Hollingsworth, M A
PMID: 10329398
Journal: Ann N Y Acad Sci. 1999 Jun 30;880:238-42.
Title: CD44, bFGF and hyaluronan in human pancreatic cancer cell lines.
Author: Ringel, J|Rychly, J|Nebe, B|Schmidt, C|Muller, P|Ringel, J|Emmrich, J|Liebe, S|Lohr, M
PMID: 10415869
Journal: Pancreas. 1999 Nov;19(4):362-9.
Title: Cytokines modulate MIA PaCa 2 and CAPAN-1 adhesion to extracellular matrix proteins.
Author: Stefani, A L|Basso, D|Panozzo, M P|Greco, E|Mazza, S|Zancanaro, F|De Franchis, G|Plebani, M
PMID: 10547196
Journal: Pol J Pathol. 1999;50(3):145-53.
Title: CD44 isoforms expression in intraductal and invasive pancreatic cancer and its correlation to p53 gene mutations.
Author: Tomaszewska, R|Nowak, K|Stachura, J
PMID: 10624116
Journal: Anticancer Res. 2000 Mar-Apr;20(2A):825-31.
Title: Different expression of CD44, ICAM-1, and HSP60 on primary tumor and metastases of a human pancreatic carcinoma growing in scid mice.
Author: Piselli, P|Vendetti, S|Vismara, D|Cicconi, R|Poccia, F|Colizzi, V|Delpino, A
PMID: 10810361
Journal: Teratog Carcinog Mutagen. 2001;21(1):97-106.
Title: CD44 in normal human pancreas and pancreatic carcinoma cell lines.
Author: Ringel, J|Jesnowski, R|Schmidt, C|Ringel, J|Kohler, H J|Rychly, J|Batra, S K|Lohr, M
PMID: 11135324
Journal: Anticancer Res. 2001 May-Jun;21(3C):2175-83.
Title: Diagnostic application of CD44 variant expression in pancreatic juice for detection of pancreatic neoplasm.
Author: Tsukuda, H|Matsumura, Y|Inoue, T|Kobayashi, Y|Ookawa, K|Aoki, T|Nebiki, H|Yamazaki, O|Kondo, H|Kakizoe, T
PMID: 11501843
Journal: Int J Biol Markers. 2003 Apr-Jun;18(2):130-8.
Title: CD44v10: an antimetastatic membrane glycoprotein for pancreatic cancer.
Author: Navaglia, F|Fogar, P|Greco, E|Basso, D|Stefani, A L|Mazza, S|Zambon, C F|Habeler, W|Altavilla, G|Amadori, A|Cecchetto, A|Plebani, M
PMID: 12841682
Journal: Eur J Cancer. 2005 Oct;41(15):2213-36.
Title: Molecular prognostic markers in pancreatic cancer: a systematic review.
Author: Garcea, G|Neal, C P|Pattenden, C J|Steward, W P|Berry, D P
PMID: 16146690
Journal: Cancer Sci. 2005 Nov;96(11):766-73.
Title: Invasive human pancreatic carcinoma cells adhere to endothelial tri-cellular corners and increase endothelial permeability.
Author: Nakai, Kei|Tanaka, Toshiyuki|Murai, Toshiyuki|Ohguro, Nobuyuki|Tano, Yasuo|Miyasaka, Masayuki
PMID: 16271070
Journal: J Biol Chem. 2006 Mar 3;281(9):5861-8. Epub 2005 Dec 29.
Title: Tumor cells enhance their own CD44 cleavage and motility by generating hyaluronan fragments.
Author: Sugahara, Kazuki N|Hirata, Takako|Hayasaka, Haruko|Stern, Robert|Murai, Toshiyuki|Miyasaka, Masayuki
PMID: 16407205
Journal: Pancreas. 2006 May;32(4):396-402.
Title: The expression of adhesion molecules and the influence of inflammatory cytokines on the adhesion of human pancreatic carcinoma cells to mesothelial monolayers.
Author: van Grevenstein, Wilhelmina M U|Hofland, Leo J|Jeekel, Johannes|van Eijck, Casper H J
PMID: 16670622
Journal: Int J Gastrointest Cancer. 2006;37(4):110-9.
Title: Characterization of the CXCR4 signaling in pancreatic cancer cells.
Author: Billadeau, Daniel D|Chatterjee, Subrha|Bramati, Patricia|Sreekumar, Raghavakaimal|Shah, Vijay|Hedin, Karen|Urrutia, Raul
PMID: 18175225
Journal: Cancer Res. 2007 Feb 1;67(3):1030-7.
Title: Identification of pancreatic cancer stem cells.
Author: Li, Chenwei|Heidt, David G|Dalerba, Piero|Burant, Charles F|Zhang, Lanjing|Adsay, Volkan|Wicha, Max|Clarke, Michael F|Simeone, Diane M
PMID: 17283135
Journal: Pancreas. 2007 May;34(4):429-35.
Title: Establishment of clonal colony-forming assay for propagation of pancreatic cancer cells with stem cell properties.
Author: Gou, Shanmiao|Liu, Tao|Wang, Chunyou|Yin, Tao|Li, Kai|Yang, Ming|Zhou, Jing
PMID: 17446842
Journal: Ann Surg Oncol. 2007 Dec;14(12):3629-37. Epub 2007 Oct 2.
Title: Development and characterization of gemcitabine-resistant pancreatic tumor cells.
Author: Shah, Ami N|Summy, Justin M|Zhang, Jing|Park, Serk In|Parikh, Nila U|Gallick, Gary E
PMID: 17909916
Journal: Pancreas. 2008 May;36(4):e15-23.
Title: Inhibition of human pancreatic cell line MIA PaCa2 proliferation by HA-But, a hyaluronic butyric ester: a preliminary report.
Author: Pellizzaro, Cinzia|Speranza, Annalisa|Zorzet, Sonia|Crucil, Ilaria|Sava, Gianni|Scarlata, Ignazio|Cantoni, Silvia|Fedeli, Maya|Coradini, Danila
PMID: 18437074
Journal: J Clin Oncol. 2008 Jun 10;26(17):2806-12.
Title: Pancreatic cancer stem cells.
Author: Lee, Cheong J|Dosch, Joseph|Simeone, Diane M
PMID: 18539958
Journal: Transl Oncol. 2008 Mar;1(1):14-8.
Title: Human pancreatic cancer stem cells: implications for how we treat pancreatic cancer.
Author: Lee, Cheong J|Li, Chenwei|Simeone, Diane M
PMID: 18607507
Journal: World J Gastroenterol. 2008 Jun 28;14(24):3903-7.
Title: Isolation and biological analysis of tumor stem cells from pancreatic adenocarcinoma.
Author: Huang, Peng|Wang, Chun-You|Gou, Shan-Miao|Wu, He-Shui|Liu, Tao|Xiong, Jiang-Xin
PMID: 18609717
Journal: J Cell Physiol. 2008 Dec;217(3):598-604.
Title: Cancer initiating cells or cancer stem cells in the gastrointestinal tract and liver.
Author: Zou, Gang-Ming
PMID: 18651561
Journal: Cancer Res. 2008 Sep 1;68(17):7191-9.
Title: Chondroitin sulfate E fragments enhance CD44 cleavage and CD44-dependent motility in tumor cells.
Author: Sugahara, Kazuki N|Hirata, Takako|Tanaka, Toshiyuki|Ogino, Shinji|Takeda, Mitsuhiro|Terasawa, Hiroaki|Shimada, Ichio|Tamura, Jun-ichi|ten Dam, Gerdy B|van Kuppevelt, Toin H|Miyasaka, Masayuki
PMID: 18757435
Journal: Gut. 2009 Jul;58(7):949-63.
Title: Sulforaphane targets pancreatic tumour-initiating cells by NF-kappaB-induced antiapoptotic signalling.
Author: Kallifatidis, G|Rausch, V|Baumann, B|Apel, A|Beckermann, B M|Groth, A|Mattern, J|Li, Z|Kolb, A|Moldenhauer, G|Altevogt, P|Wirth, T|Werner, J|Schemmer, P|Buchler, M W|Salnikov, A V|Herr, I
PMID: 18829980
Journal: Mol Cancer Ther. 2009 Feb;8(2):310-4.
Title: A direct pancreatic cancer xenograft model as a platform for cancer stem cell therapeutic development.
Author: Jimeno, Antonio|Feldmann, Georg|Suarez-Gauthier, Ana|Rasheed, Zeshaan|Solomon, Anna|Zou, Gang-Ming|Rubio-Viqueira, Belen|Garcia-Garcia, Elena|Lopez-Rios, Fernando|Matsui, William|Maitra, Anirban|Hidalgo, Manuel
PMID: 19174553
Journal: Int J Mol Med. 2009 Jun;23(6):763-9.
Title: Transcriptional mechanisms of WNT5A based on NF-kappaB, Hedgehog, TGFbeta, and Notch signaling cascades.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 19424602
Journal: Methods Mol Biol. 2009;568:161-73.
Title: Identification of human pancreatic cancer stem cells.
Author: Li, Chenwei|Lee, C J|Simeone, Diane M
PMID: 19582426
Journal: Int J Cancer. 2009 Nov 15;125(10):2323-31.
Title: CD44-positive cells are responsible for gemcitabine resistance in pancreatic cancer cells.
Author: Hong, Sung Pil|Wen, Jing|Bang, Seungmin|Park, Seungwoo|Song, Si Young
PMID: 19598259
Journal: PLoS One. 2009 Aug 28;4(8):e6816.
Title: MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells.
Author: Ji, Qing|Hao, Xinbao|Zhang, Min|Tang, Wenhua|Yang, Meng|Li, Ling|Xiang, Debing|Desano, Jeffrey T|Bommer, Guido T|Fan, Daiming|Fearon, Eric R|Lawrence, Theodore S|Xu, Liang
PMID: 19714243
Journal: Curr Mol Med. 2009 Sep;9(7):873-86.
Title: Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation.
Author: Katoh, Y|Katoh, M
PMID: 19860666
Journal: Int J Cancer. 2010 Jul 1;127(1):246-7.
Title: Evidence linking CD44-positive cells and gemcitabine resistance in pancreatic cancer cells: need for further substantiation.
Author: Hagmann, Wolfgang|Jesnowski, Ralf|Matthias Lohr, Johannes
PMID: 19877122
Journal: Int J Oncol. 2010 Feb;36(2):415-20.
Title: Integrative genomic analyses of CXCR4: transcriptional regulation of CXCR4 based on TGFbeta, Nodal, Activin signaling and POU5F1, FOXA2, FOXC2, FOXH1, SOX17, and GFI1 transcription factors.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 20043076
Journal: Eur J Cancer. 2010 May;46(7):1271-7.
Title: CD44, a therapeutic target for metastasising tumours.
Author: Orian-Rousseau, Veronique
PMID: 20303742
Journal: Oncol Rep. 2010 May;23(5):1375-82.
Title: Side population in the pancreatic cancer cell lines SW1990 and CFPAC-1 is enriched with cancer stem-like cells.
Author: Yao, Jie|Cai, Hui-Hua|Wei, Ji-Shu|An, Yong|Ji, Zhen-Ling|Lu, Zi-Peng|Wu, Jun-Li|Chen, Ping|Jiang, Kui-Rong|Dai, Cun-Cai|Qian, Zhu-Yin|Xu, Ze-Kuan|Miao, Yi
PMID: 20372854
Journal: J Vis Exp. 2010 Sep 26;(43). pii: 2169.
Title: Isolation of stem cells from human pancreatic cancer xenografts.
Author: Rasheed, Zeshaan|Wang, Qiuju|Matsui, William
PMID: 20972397
Journal: Zhonghua Wai Ke Za Zhi. 2010 Jul 1;48(13):999-1003.
Title: [Establish a gemcitabine-resistant pancreatic cancer cell line SW1990/GZ and research the relationship between SW1990/GZ and pancreatic cancer stem cell].
Author: An, Yong|Yao, Jie|Wei, Ji-Shu|Lu, Zi-Peng|Cai, Hui-Hua|Dai, Cun-Cai|Qian, Zhu-Yin|Xu, Ze-Kuan|Miao, Yi
PMID: 21054984
Journal: Exp Ther Med. 2010 Jan;1(1):211-216.
Title: Genomic analysis of invasion-metastasis-related factors in pancreatic cancer cells.
Author: Tan, Xiaodong|Zhou, Lei|Wang, Wei|Wang, Baosheng|Egami, Hiroshi|Baba, Hideo|Dai, Xianwei
PMID: 23136617
Journal: Biosci Rep. 2011 Feb;31(1):45-55.
Title: Pancreatic cancer spheres are more than just aggregates of stem marker-positive cells.
Author: Gaviraghi, Margherita|Tunici, Patrizia|Valensin, Silvia|Rossi, Marco|Giordano, Cinzia|Magnoni, Letizia|Dandrea, Mario|Montagna, Licia|Ritelli, Rossana|Scarpa, Aldo|Bakker, Annette
PMID: 20426768
Journal: Carcinogenesis. 2011 Apr;32(4):445-51.
Title: Hedgehog signaling and therapeutics in pancreatic cancer.
Author: Kelleher, Fergal C
PMID: 21186299
Journal: PLoS One. 2011 Jan 31;6(1):e16530.
Title: Resveratrol inhibits pancreatic cancer stem cell characteristics in human and KrasG12D transgenic mice by inhibiting pluripotency maintaining factors and epithelial-mesenchymal transition.
Author: Shankar, Sharmila|Nall, Dara|Tang, Su-Ni|Meeker, Daniel|Passarini, Jenna|Sharma, Jay|Srivastava, Rakesh K
PMID: 21304978
Journal: J Oncol. 2011;2011:135039.
Title: Phenotypic heterogeneity of breast cancer stem cells.
Author: Lorico, Aurelio|Rappa, Germana
PMID: 21317983
Journal: PLoS One. 2011 Mar 9;6(3):e17850.
Title: Anti-tumor activity of a novel compound-CDF is mediated by regulating miR-21, miR-200, and PTEN in pancreatic cancer.
Author: Bao, Bin|Ali, Shadan|Kong, Dejuan|Sarkar, Sanila H|Wang, Zhiwei|Banerjee, Sanjeev|Aboukameel, Amro|Padhye, Subhash|Philip, Philip A|Sarkar, Fazlul H
PMID: 21408027
Journal: Cancer Lett. 2011 Aug 1;307(1):26-36.
Title: Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells.
Author: Bao, Bin|Wang, Zhiwei|Ali, Shadan|Kong, Dejuan|Li, Yiwei|Ahmad, Aamir|Banerjee, Sanjeev|Azmi, Asfar S|Miele, Lucio|Sarkar, Fazlul H
PMID: 21463919
Journal: J Cell Biochem. 2011 Sep;112(9):2296-306.
Title: Over-expression of FoxM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells.
Author: Bao, Bin|Wang, Zhiwei|Ali, Shadan|Kong, Dejuan|Banerjee, Sanjeev|Ahmad, Aamir|Li, Yiwei|Azmi, Asfar S|Miele, Lucio|Sarkar, Fazlul H
PMID: 21503965
Journal: Mol Cancer Ther. 2011 Aug;10(8):1470-80.
Title: Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice.
Author: Pramanik, Dipankar|Campbell, Nathaniel R|Karikari, Collins|Chivukula, Raghu|Kent, Oliver A|Mendell, Joshua T|Maitra, Anirban
PMID: 21622730
Journal: Swiss Med Wkly. 2011 May 31;141:w13208.
Title: Cyclopamine reverts acquired chemoresistance and down-regulates cancer stem cell markers in pancreatic cancer cell lines.
Author: Yao, Jie|An, Yong|Wie, Ji-shu|Ji, Zhen-ling|Lu, Zi-peng|Wu, Jun-li|Jiang, Kui-rong|Chen, Ping|Xu, Ze-kuan|Miao, Yi
PMID: 21630164
Journal: Int J Mol Sci. 2011;12(3):1595-604.
Title: Cancer stem-like cells enriched in Panc-1 spheres possess increased migration ability and resistance to gemcitabine.
Author: Yin, Tao|Wei, Hongji|Gou, Shanmiao|Shi, Pengfei|Yang, Zhiyong|Zhao, Gang|Wang, Chunyou
PMID: 21673909
Journal: PLoS One. 2011;6(6):e20636.
Title: ALDH activity selectively defines an enhanced tumor-initiating cell population relative to CD133 expression in human pancreatic adenocarcinoma.
Author: Kim, Michael P|Fleming, Jason B|Wang, Huamin|Abbruzzese, James L|Choi, Woonyoung|Kopetz, Scott|McConkey, David J|Evans, Douglas B|Gallick, Gary E
PMID: 21695188
Journal: J Cell Biochem. 2011 Dec;112(12):3549-54.
Title: Stem-like and non-stem human pancreatic cancer cells distinguished by morphology and metastatic behavior.
Author: Hassanein, Mohamed K|Suetsugu, Atsushi|Saji, Shigetoyo|Moriwaki, Hisataka|Bouvet, Michael|Moossa, A R|Hoffman, Robert M
PMID: 21780159
Journal: Hepatobiliary Pancreat Dis Int. 2011 Aug;10(4):428-34.
Title: Expression of CD44, CD24 and ESA in pancreatic adenocarcinoma cell lines varies with local microenvironment.
Author: Wei, Hong-Ji|Yin, Tao|Zhu, Zhu|Shi, Peng-Fei|Tian, Yuan|Wang, Chun-You
PMID: 21813394
Journal: Gastroenterology. 2011 Dec;141(6):2218-2227.e5.
Title: c-Met is a marker of pancreatic cancer stem cells and therapeutic target.
Author: Li, Chenwei|Wu, Jing-Jiang|Hynes, Mark|Dosch, Joseph|Sarkar, Bedabrata|Welling, Theodore H|Pasca di Magliano, Marina|Simeone, Diane M
PMID: 21864475
Journal: Anticancer Res. 2011 Sep;31(9):2699-704.
Title: Pomegranate extract induces cell cycle arrest and alters cellular phenotype of human pancreatic cancer cells.
Author: Nair, Vidhya|Dai, Zhaoli|Khan, Maruf|Ciolino, Henry P
PMID: 21868510
Journal: J Korean Surg Soc. 2011 Oct;81(4):263-70.
Title: Significance of CD133 as a cancer stem cell markers focusing on the tumorigenicity of pancreatic cancer cell lines.
Author: Lee, Hyun Joo|You, Dong Do|Choi, Dong Wook|Choi, Young Sil|Kim, Seong Joo|Won, Yong Sung|Moon, Hyoun Jong
PMID: 22111082
Journal: Zhonghua Yi Xue Za Zhi. 2011 Nov 29;91(44):3107-10.
Title: [Altered expressions of embryonic stem-related genes in pancreatic cancer stem cell].
Author: Lu, Yu-hua|Zhu, Hui|Wang, Zhi-wei|Fan, Xiang-jun|Zhu, Sha-jun|Li, Xiao-hong|Wang, Yao|Lu, Jun-jie|Zhu, Ming-yan
PMID: 22340650
Journal: Cancer Prev Res (Phila). 2012 Mar;5(3):355-64.
Title: Metformin inhibits cell proliferation, migration and invasion by attenuating CSC function mediated by deregulating miRNAs in pancreatic cancer cells.
Author: Bao, Bin|Wang, Zhiwei|Ali, Shadan|Ahmad, Aamir|Azmi, Asfar S|Sarkar, Sanila H|Banerjee, Sanjeev|Kong, Dejuan|Li, Yiwei|Thakur, Shivam|Sarkar, Fazlul H
PMID: 22086681
Journal: Cancer Res. 2012 Jan 1;72(1):335-45.
Title: Curcumin analogue CDF inhibits pancreatic tumor growth by switching on suppressor microRNAs and attenuating EZH2 expression.
Author: Bao, Bin|Ali, Shadan|Banerjee, Sanjeev|Wang, Zhiwei|Logna, Farah|Azmi, Asfar S|Kong, Dejuan|Ahmad, Aamir|Li, Yiwei|Padhye, Subhash|Sarkar, Fazlul H
PMID: 22108826
Journal: J Gastroenterol Hepatol. 2012 Mar;27 Suppl 2:15-8.
Title: Biological and clinical relevance of stem cells in pancreatic adenocarcinoma.
Author: Rasheed, Zeshaan A|Matsui, William
PMID: 22320910
Journal: Oncol Rep. 2012 May;27(5):1599-605.
Title: Epithelial mesenchymal transition correlates with CD24+CD44+ and CD133+ cells in pancreatic cancer.
Author: Zhang, Ye|Wei, Jishu|Wang, Hui|Xue, Xiaofeng|An, Yong|Tang, Dong|Yuan, Zhongxu|Wang, Feitong|Wu, Junli|Zhang, Jingjing|Miao, Yi
PMID: 22322379
Journal: J Proteome Res. 2012 Apr 6;11(4):2272-81.
Title: Identification of glycoprotein markers for pancreatic cancer CD24+CD44+ stem-like cells using nano-LC-MS/MS and tissue microarray.
Author: Zhu, Jianhui|He, Jintang|Liu, Yashu|Simeone, Diane M|Lubman, David M
PMID: 22335271
Journal: Vitam Horm. 2012;88:355-78.
Title: Aberrations and therapeutics involving the developmental pathway Hedgehog in pancreatic cancer.
Author: Kelleher, Fergal C|McDermott, Raymond
PMID: 22391312
Journal: Mol Cell Proteomics. 2012 Jul;11(7):M112.017558.
Title: Metabolic flux increases glycoprotein sialylation: implications for cell adhesion and cancer metastasis.
Author: Almaraz, Ruben T|Tian, Yuan|Bhattarcharya, Rahul|Tan, Elaine|Chen, Shih-Hsun|Dallas, Matthew R|Chen, Li|Zhang, Zhen|Zhang, Hui|Konstantopoulos, Konstantinos|Yarema, Kevin J
PMID: 22457533
Journal: J Oncol. 2012;2012:796729.
Title: Adamantyl Retinoid-Related Molecules Induce Apoptosis in Pancreatic Cancer Cells by Inhibiting IGF-1R and Wnt/beta-Catenin Pathways.
Author: Farhana, Lulu|Dawson, Marcia I|Das, Jayanta K|Murshed, Farhan|Xia, Zebin|Hadden, Timothy J|Hatfield, James|Fontana, Joseph A
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Journal: Environ Health Perspect. 2012 Sep;120(9):1265-71.
Title: Chronic cadmium exposure in vitro causes acquisition of multiple tumor cell characteristics in human pancreatic epithelial cells.
Author: Qu, Wei|Tokar, Erik J|Kim, Andrew J|Bell, Matthew W|Waalkes, Michael P
PMID: 22626610
Journal: PLoS One. 2012;7(5):e37509.
Title: Whole blood DNA aberrant methylation in pancreatic adenocarcinoma shows association with the course of the disease: a pilot study.
Author: Dauksa, Albertas|Gulbinas, Antanas|Barauskas, Giedrius|Pundzius, Juozas|Oldenburg, Johannes|El-Maarri, Osman
PMID: 22629410
Journal: Med Mol Morphol. 2012 Jun;45(2):59-65.
Title: Nestin and other putative cancer stem cell markers in pancreatic cancer.
Author: Matsuda, Yoko|Kure, Shoko|Ishiwata, Toshiyuki
PMID: 22718289
Journal: Oncol Lett. 2012 Jan;3(1):229-233.
Title: Transforming growth factor beta-induced epithelial-mesenchymal transition increases cancer stem-like cells in the PANC-1 cell line.
Author: Wang, Hui|Wu, Junli|Zhang, Ye|Xue, Xiaofeng|Tang, Dong|Yuan, Zhongxu|Chen, Minyong|Wei, Jishu|Zhang, Jingjing|Miao, Yi
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Journal: Cancer Gene Ther. 2012 Sep;19(9):652-8.
Title: TRAIL-engineered pancreas-derived mesenchymal stem cells: characterization and cytotoxic effects on pancreatic cancer cells.
Author: Moniri, M R|Sun, X-Y|Rayat, J|Dai, D|Ao, Z|He, Z|Verchere, C B|Dai, L-J|Warnock, G L
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Journal: Oncol Lett. 2012 Jun;3(6):1186-1190.
Title: Neoadjuvant chemotherapy with gemcitabine for pancreatic cancer increases in situ expression of the apoptosis marker M30 and stem cell marker CD44.
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Journal: Neoplasia. 2012 Jun;14(6):519-25.
Title: Sensitization of pancreatic cancer stem cells to gemcitabine by Chk1 inhibition.
Author: Venkatesha, Venkatasubbaiah A|Parsels, Leslie A|Parsels, Joshua D|Zhao, Lili|Zabludoff, Sonya D|Simeone, Diane M|Maybaum, Jonathan|Lawrence, Theodore S|Morgan, Meredith A
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Journal: Front Endocrinol (Lausanne). 2012 Aug 3;3:90.
Title: The role of head and neck squamous cell carcinoma cancer stem cells in tumorigenesis, metastasis, and treatment failure.
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Journal: Oncol Rep. 2012 Oct;28(4):1301-8.
Title: Evaluation of CD44 and CD133 as cancer stem cell markers for colorectal cancer.
Author: Wang, Chunxia|Xie, Jingping|Guo, Jiasong|Manning, H Charles|Gore, John C|Guo, Ning
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Journal: PLoS One. 2012;7(8):e42991.
Title: Spatio-temporal patterns of pancreatic cancer cells expressing CD44 isoforms on supported membranes displaying hyaluronic acid oligomers arrays.
Author: Kaindl, Thomas|Rieger, Harden|Kaschel, Lisa-Mareike|Engel, Ulrike|Schmaus, Anja|Sleeman, Jonathan|Tanaka, Motomu
PMID: 22916191
Journal: Eur Surg Res. 2012;49(2):88-98.
Title: Pancreatic carcinoma cell lines reflect frequency and variability of cancer stem cell markers in clinical tissue.
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Journal: Stem Cell Res. 2012 Nov;9(3):249-60.
Title: Comparative testing of various pancreatic cancer stem cells results in a novel class of pancreatic-cancer-initiating cells.
Author: Jaiswal, Kshama R|Xin, Hong-Wu|Anderson, Andrew|Wiegand, Gordon|Kim, Bo|Miller, Tyler|Hari, Danielle|Ray, Satyajit|Koizumi, Tomotake|Rudloff, Udo|Thorgeirsson, Snorri S|Avital, Itzhak
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Journal: Int J Oncol. 2012 Dec;41(6):2093-102.
Title: Pancreatic cancer cells surviving gemcitabine treatment express markers of stem cell differentiation and epithelial-mesenchymal transition.
Author: Quint, Karl|Tonigold, Manuel|Di Fazio, Pietro|Montalbano, Roberta|Lingelbach, Susanne|Ruckert, Felix|Alinger, Beate|Ocker, Matthias|Neureiter, Daniel
PMID: 23026911
Journal: PLoS One. 2012;7(10):e46514.
Title: Epithelial mesenchymal transition and pancreatic tumor initiating CD44+/EpCAM+ cells are inhibited by gamma-secretase inhibitor IX.
Author: Palagani, Vindhya|El Khatib, Mona|Kossatz, Uta|Bozko, Przemyslaw|Muller, Martin R|Manns, Michael P|Krech, Till|Malek, Nisar P|Plentz, Ruben R
PMID: 23094026
Journal: J Cell Physiol. 2013 Mar;228(3):556-62.
Title: Activated K-Ras and INK4a/Arf deficiency promote aggressiveness of pancreatic cancer by induction of EMT consistent with cancer stem cell phenotype.
Author: Wang, Zhiwei|Ali, Shadan|Banerjee, Sanjeev|Bao, Bin|Li, Yiwei|Azmi, Asfar S|Korc, Murray|Sarkar, Fazlul H
PMID: 22806240
Journal: Acta Histochem. 2013 May;115(4):349-56.
Title: CD133(+)/CD44(+)/Oct4(+)/Nestin(+) stem-like cells isolated from Panc-1 cell line may contribute to multi-resistance and metastasis of pancreatic cancer.
Author: Wang, Dongqing|Zhu, Haitao|Zhu, Ying|Liu, Yanfang|Shen, Huiling|Yin, Ruigen|Zhang, Zhijian|Su, Zhaoliang
PMID: 23036582
Journal: Cancer Lett. 2013 Jul 1;334(2):211-20.
Title: miRNA profiling in pancreatic cancer and restoration of chemosensitivity.
Author: Singh, Saurabh|Chitkara, Deepak|Kumar, Virender|Behrman, Stephen W|Mahato, Ram I
PMID: 23073476
Journal: Biochim Biophys Acta. 2013 May;1828(5):1396-404.
Title: Targeting gemcitabine containing liposomes to CD44 expressing pancreatic adenocarcinoma cells causes an increase in the antitumoral activity.
Author: Dalla Pozza, Elisa|Lerda, Carlotta|Costanzo, Chiara|Donadelli, Massimo|Dando, Ilaria|Zoratti, Elisa|Scupoli, Maria Teresa|Beghelli, Stefania|Scarpa, Aldo|Fattal, Elias|Arpicco, Silvia|Palmieri, Marta
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Journal: Curr Protoc Stem Cell Biol. 2013 Feb;Chapter 3:Unit 3.7.
Title: In vitro enrichment of tumor-initiating cells from human established cell lines.
Author: Benayoun, Liat|Shaked, Yuval
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Journal: Int J Nanomedicine. 2013;8:1167-76.
Title: A tissue-engineered subcutaneous pancreatic cancer model for antitumor drug evaluation.
Author: He, Qingyi|Wang, Xiaohui|Zhang, Xing|Han, Huifang|Han, Baosan|Xu, Jianzhong|Tang, Kanglai|Fu, Zhiren|Yin, Hao
PMID: 23658483
Journal: Cell Tissue Res. 2013 Jul;353(1):139-51.
Title: B7-H4 enhances oncogenicity and inhibits apoptosis in pancreatic cancer cells.
Author: Qian, Yun|Hong, Bo|Shen, Ling|Wu, Zhigang|Yao, Hangping|Zhang, Lihuang
PMID: 23660627
Journal: Cancer Sci. 2013 Aug;104(8):1127-34.
Title: Histological and prognostic importance of CD44(+) /CD24(+) /EpCAM(+) expression in clinical pancreatic cancer.
Author: Ohara, Yusuke|Oda, Tatsuya|Sugano, Masato|Hashimoto, Shinji|Enomoto, Tsuyoshi|Yamada, Keiichi|Akashi, Yoshimasa|Miyamoto, Ryoichi|Kobayashi, Akihiko|Fukunaga, Kiyoshi|Morishita, Yukio|Ohkohchi, Nobuhiro
PMID: 23679813
Journal: Front Biosci (Landmark Ed). 2013 Jun 1;18:795-802.
Title: Cancer stem cell in the progression and therapy of pancreatic cancer.
Author: Xu, Lantao
PMID: 23747847
Journal: EMBO Mol Med. 2013 Sep;5(9):1322-34.
Title: A novel epigenetic CREB-miR-373 axis mediates ZIP4-induced pancreatic cancer growth.
Author: Zhang, Yuqing|Yang, Jingxuan|Cui, Xiaobo|Chen, Yong|Zhu, Vivian F|Hagan, John P|Wang, Huamin|Yu, Xianjun|Hodges, Sally E|Fang, Jing|Chiao, Paul J|Logsdon, Craig D|Fisher, William E|Brunicardi, F Charles|Chen, Changyi|Yao, Qizhi|Fernandez-Zapico, Martin E|
PMID: 23857777
Journal: Mol Biol Cell. 2013 Sep;24(17):2620-32.
Title: Multifunctional roles of urokinase plasminogen activator (uPA) in cancer stemness and chemoresistance of pancreatic cancer.
Author: Asuthkar, Swapna|Stepanova, Victoria|Lebedeva, Tatiana|Holterman, Aixuan L|Estes, Norman|Cines, Douglas B|Rao, Jasti S|Gondi, Christopher S
PMID: 23864708
Journal: Pancreatology. 2013 Jul-Aug;13(4):384-92.
Title: WNT5A/JNK signaling regulates pancreatic cancer cells migration by Phosphorylating Paxillin.
Author: Wei, Wei|Li, Hongyue|Li, Na|Sun, Huihui|Li, Qiang|Shen, Xiaohong
PMID: 23890137
Journal: Oncogenesis. 2013 Aug 5;2:e61.
Title: SOX2 promotes dedifferentiation and imparts stem cell-like features to pancreatic cancer cells.
Author: Herreros-Villanueva, M|Zhang, J-S|Koenig, A|Abel, E V|Smyrk, T C|Bamlet, W R|de Narvajas, A A-M|Gomez, T S|Simeone, D M|Bujanda, L|Billadeau, D D
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Journal: Onco Targets Ther. 2013 Aug 19;6:1129-38.
Title: Arsenic trioxide inhibits viability of pancreatic cancer stem cells in culture and in a xenograft model via binding to SHH-Gli.
Author: Han, Jin-Bin|Sang, Feng|Chang, Jin-Jia|Hua, Yong-Qiang|Shi, Wei-Dong|Tang, Li-Hua|Liu, Lu-Ming
PMID: 23990729
Journal: Transl Oncol. 2013 Dec 1;6(6):649-59. eCollection 2013 Dec 1.
Title: Antidiabetic Drug Metformin Prevents Progression of Pancreatic Cancer by Targeting in Part Cancer Stem Cells and mTOR Signaling.
Author: Mohammed, Altaf|Janakiram, Naveena B|Brewer, Misty|Ritchie, Rebekah L|Marya, Anuj|Lightfoot, Stan|Steele, Vernon E|Rao, Chinthalapally V
PMID: 24466367
Journal: Stem Cell Res. 2014 Jan;12(1):1-10.
Title: uPAR-controlled oncolytic adenoviruses eliminate cancer stem cells in human pancreatic tumors.
Author: Sobrevals, Luciano|Mato-Berciano, Ana|Urtasun, Nerea|Mazo, Adela|Fillat, Cristina
PMID: 24141108
Journal: Cancer Lett. 2014 Apr 28;346(1):104-13.
Title: MUC4-induced nuclear translocation of beta-catenin: a novel mechanism for growth, metastasis and angiogenesis in pancreatic cancer.
Author: Zhi, Xiaofei|Tao, Jinqiu|Xie, Kunling|Zhu, Yi|Li, Zheng|Tang, Jie|Wang, Weizhi|Xu, Hao|Zhang, Jingjing|Xu, Zekuan
PMID: 24374017
Journal: Gastroenterology. 2014 Apr;146(4):1108-18.
Title: Antibody against CD44s inhibits pancreatic tumor initiation and postradiation recurrence in mice.
Author: Li, Ling|Hao, Xinbao|Qin, Jun|Tang, Wenhua|He, Fengtian|Smith, Amber|Zhang, Min|Simeone, Diane M|Qiao, Xiaotan T|Chen, Zhi-Nan|Lawrence, Theodore S|Xu, Liang
PMID: 24397969
Journal: Nat Rev Gastroenterol Hepatol. 2014 Feb;11(2):73.
Title: Pancreatic cancer: pancreatic tumour formation and recurrence after radiotherapy are blocked by targeting CD44.
Author: Wood, Natalie J
PMID: 24445614
Journal: PLoS One. 2014 Feb 5;9(2):e87868.
Title: Antitumor efficacy of alpha-solanine against pancreatic cancer in vitro and in vivo.
Author: Lv, Chongqing|Kong, Hongru|Dong, Guohua|Liu, Lewei|Tong, Kun|Sun, Hongwei|Chen, Bicheng|Zhang, Chunwu|Zhou, Mengtao
PMID: 24505326
Journal: PLoS One. 2014 Feb 5;9(2):e87979.
Title: Response of breast cancer cells and cancer stem cells to metformin and hyperthermia alone or combined.
Author: Lee, Hyemi|Park, Heon Joo|Park, Chang-Shin|Oh, Eun-Taex|Choi, Bo-Hwa|Williams, Brent|Lee, Chung K|Song, Chang W
PMID: 24505341
Journal: BMC Cancer. 2014 Feb 12;14:85.
Title: MiR-200a inhibits epithelial-mesenchymal transition of pancreatic cancer stem cell.
Author: Lu, Yuhua|Lu, Jingjing|Li, Xiaohong|Zhu, Hui|Fan, Xiangjun|Zhu, Shajun|Wang, Yao|Guo, Qingsong|Wang, Lei|Huang, Yan|Zhu, Mingyan|Wang, Zhiwei
PMID: 24521357
Journal: Pancreatology. 2014 Jan-Feb;14(1):48-53.
Title: Notch pathway activation is associated with pancreatic cancer treatment failure.
Author: Lee, Jin Young|Song, Si Young|Park, Jeong Youp
PMID: 24555978
Journal: Biomed Res Int. 2014;2014:760303.
Title: The low chamber pancreatic cancer cells had stem-like characteristics in modified transwell system: is it a novel method to identify and enrich cancer stem-like cells?
Author: Wang, Dongqing|Zhu, Haitao|Liu, Yanfang|Liu, Qing|Xie, Xiaodong|Zhou, Yuepeng|Zhang, Lirong|Zhu, Yan|Zhang, Zhijian|Su, Zhaoliang
PMID: 24689055
Journal: Diagn Pathol. 2014 Apr 8;9:79.
Title: CD44v/CD44s expression patterns are associated with the survival of pancreatic carcinoma patients.
Author: Li, Zhonghu|Chen, Kai|Jiang, Peng|Zhang, Xi|Li, Xiaowu|Li, Zhihua
PMID: 24708709
Journal: J Biol Chem. 2014 May 23;289(21):14520-33.
Title: Pancreatic cancer stem-like cells display aggressive behavior mediated via activation of FoxQ1.
Author: Bao, Bin|Azmi, Asfar S|Aboukameel, Amro|Ahmad, Aamir|Bolling-Fischer, Aliccia|Sethi, Seema|Ali, Shadan|Li, Yiwei|Kong, Dejuan|Banerjee, Sanjeev|Back, Jessica|Sarkar, Fazlul H
PMID: 24719318
Journal: Exp Cell Res. 2014 Jun 10;324(2):146-56.
Title: Influence of interferon-alpha on the expression of the cancer stem cell markers in pancreatic carcinoma cells.
Author: Zhu, Yifan|Karakhanova, Svetlana|Huang, Xiaolun|Deng, Shao Ping|Werner, Jens|Bazhin, Alexandr V
PMID: 24726912
Journal: Stem Cells Dev. 2014 Aug 15;23(16):1947-58.
Title: Differentially expressed miRNAs in cancer-stem-like cells: markers for tumor cell aggressiveness of pancreatic cancer.
Author: Bao, Bin|Ali, Shadan|Ahmad, Aamir|Li, Yiwei|Banerjee, Sanjeev|Kong, Dejuan|Aboukameel, Amro|Mohammad, Ramzi|Van Buren, Eric|Azmi, Asfar S|Sarkar, Fazlul H
PMID: 24734907
Journal: Oncol Rep. 2014 Jul;32(1):153-8.
Title: Establishment of hypoxia induction in an in vivo animal replacement model for experimental evaluation of pancreatic cancer.
Author: Bauer, Nathalie|Liu, Li|Aleksandrowicz, Ewa|Herr, Ingrid
PMID: 24842335
Journal: Adv Biol Regul. 2014 Sep;56:45-50.
Title: Pancreatic cancer stem cells: association with cell surface markers, prognosis, resistance, metastasis and treatment.
Author: Fitzgerald, Timothy L|McCubrey, James A
PMID: 24925031
Journal: Mol Pharm. 2014 Sep 2;11(9):3112-22.
Title: Targeted nanogel conjugate for improved stability and cellular permeability of curcumin: synthesis, pharmacokinetics, and tumor growth inhibition.
Author: Wei, Xin|Senanayake, Thulani H|Bohling, Anna|Vinogradov, Serguei V
PMID: 25072100
Journal: Anticancer Res. 2014 Aug;34(8):4509-19.
Title: An epithelial cell adhesion molecule- and CD3-bispecific antibody plus activated T-cells can eradicate chemoresistant cancer stem-like pancreatic carcinoma cells in vitro.
Author: Umebayashi, Masayo|Kiyota, Akifumi|Koya, Norihiro|Tanaka, Hiroto|Onishi, Hideya|Katano, Mitsuo|Morisaki, Takashi
PMID: 25075094
Journal: Sci Rep. 2014 Aug 1;4:5911.
Title: The IL-8/CXCR1 axis is associated with cancer stem cell-like properties and correlates with clinical prognosis in human pancreatic cancer cases.
Author: Chen, Lianyu|Fan, Jie|Chen, Hao|Meng, Zhiqiang|Chen, Zhen|Wang, Peng|Liu, Luming
PMID: 25081383
Journal: PLoS One. 2014 Sep 3;9(9):e106343.
Title: A miRNA signature of chemoresistant mesenchymal phenotype identifies novel molecular targets associated with advanced pancreatic cancer.
Author: Bera, Alakesh|VenkataSubbaRao, Kolaparthi|Manoharan, Muthu Saravanan|Hill, Ping|Freeman, James W
PMID: 25184537
Journal: BMC Cancer. 2014 Sep 21;14:687.
Title: Immunohistochemical analysis of cancer stem cell markers in pancreatic adenocarcinoma patients after neoadjuvant chemoradiotherapy.
Author: Mizukami, Tatsuzo|Kamachi, Hirofumi|Mitsuhashi, Tomoko|Tsuruga, Yosuke|Hatanaka, Yutaka|Kamiyama, Toshiya|Matsuno, Yoshihiro|Taketomi, Akinobu
PMID: 25240521
Journal: Medicina (Kaunas). 2014;50(4):237-44.
Title: Accumulation and biological effects of cobalt ferrite nanoparticles in human pancreatic and ovarian cancer cells.
Author: Pasukoniene, Vita|Mlynska, Agata|Steponkiene, Simona|Poderys, Vilius|Matulionyte, Marija|Karabanovas, Vitalijus|Statkute, Urte|Purviniene, Rasa|Krasko, Jan Aleksander|Jagminas, Arunas|Kurtinaitiene, Marija|Strioga, Marius|Rotomskis, Ricardas
PMID: 25458961
Journal: Biomed Mater. 2014 Dec 23;10(1):015004.
Title: A bioengineered murine model using CD24(+)CD44(+) pancreatic cancer stem cells for chemotherapy study.
Author: Qin, Shengqi|Deng, Yiming|Li, Jianshe|Zhang, Zhongtao
PMID: 25532534
Journal: J Cancer Stem Cell Res. 2014;2.
Title: A concise review on the current understanding of pancreatic cancer stem cells.
Author: Vaz, Arokia Priyanka|Ponnusamy, Moorthy P|Seshacharyulu, Parthasarathy|Batra, Surinder K
PMID: 26451384
Journal: Int J Oncol. 2015 Jan;46(1):78-90.
Title: Pancreatic cancer immunotherapy using a tumor lysate vaccine, engineered to express alpha-gal epitopes, targets pancreatic cancer stem cells.
Author: Tanida, Tsukasa|Tanemura, Masahiro|Miyoshi, Eiji|Nagano, Hiroaki|Furukawa, Kenta|Nonaka, Yuji|Akita, Hirofumi|Hama, Naoki|Wada, Hiroshi|Kawamoto, Koichi|Kobayashi, Shogo|Eguchi, Hidetoshi|Mori, Masaki|Doki, Yuichiro
PMID: 25354268
Journal: J Steroid Biochem Mol Biol. 2015 Apr;148:79-85.
Title: Targeting cancer stem cells in solid tumors by vitamin D.
Author: So, Jae Young|Suh, Nanjoo
PMID: 25460302
Journal: Exp Mol Pathol. 2015 Feb;98(1):41-6.
Title: Pancreatic cancer cells express CD44 variant 9 and multidrug resistance protein 1 during mitosis.
Author: Kiuchi, Shizuka|Ikeshita, Shunji|Miyatake, Yukiko|Kasahara, Masanori
PMID: 25481101
Journal: Mol Cancer Res. 2015 Jan;13(1):9-15.
Title: CD44 regulates pancreatic cancer invasion through MT1-MMP.
Author: Jiang, Wei|Zhang, Yaqing|Kane, Kevin T|Collins, Meredith A|Simeone, Diane M|di Magliano, Marina Pasca|Nguyen, Kevin Tri
PMID: 25566991
Journal: J Biol Chem. 2015 Mar 27;290(13):8632-43.
Title: Lysosomal degradation of CD44 mediates ceramide nanoliposome-induced anoikis and diminished extravasation in metastatic carcinoma cells.
Author: Haakenson, Jeremy K|Khokhlatchev, Andrei V|Choi, Younhee J|Linton, Samuel S|Zhang, Pu|Zaki, Peter M|Fu, Changliang|Cooper, Timothy K|Manni, Andrea|Zhu, Junjia|Fox, Todd E|Dong, Cheng|Kester, Mark
PMID: 25681441
Journal: Asian Pac J Cancer Prev. 2015;16(2):437-42.
Title: Establishment of a pancreatic cancer stem cell model using the SW1990 human pancreatic cancer cell line in nude mice.
Author: Pan, Yan|Gao, Song|Hua, Yong-Qiang|Liu, Lu-Ming
PMID: 25684468
Journal: Oncotarget. 2015 Mar 20;6(8):5517-35.
Title: Combination of carbon ion beam and gemcitabine causes irreparable DNA damage and death of radioresistant pancreatic cancer stem-like cells in vitro and in vivo.
Author: Sai, Sei|Wakai, Toshifumi|Vares, Guillaume|Yamada, Shigeru|Kamijo, Takehiko|Kamada, Tadashi|Shirai, Toshiyuki
PMID: 25849939
Journal: World J Gastroenterol. 2015 Apr 7;21(13):3876-87.
Title: Fucosylation is a common glycosylation type in pancreatic cancer stem cell-like phenotypes.
Author: Terao, Naoko|Takamatsu, Shinji|Minehira, Tomomi|Sobajima, Tomoaki|Nakayama, Kotarosumitomo|Kamada, Yoshihiro|Miyoshi, Eiji
PMID: 25852272
Journal: BMC Cancer. 2015 Apr 11;15:266.
Title: The involvement of insulin-like growth factor 2 binding protein 3 (IMP3) in pancreatic cancer cell migration, invasion, and adhesion.
Author: Pasiliao, Clarissa C|Chang, Che-Wei A|Sutherland, Brent W|Valdez, Shannon M|Schaeffer, David|Yapp, Donald T|Ng, Sylvia S W
PMID: 25886367
Journal: Gastroenterol Res Pract. 2015;2015:568981.
Title: Molecular mechanism of local drug delivery with Paclitaxel-eluting membranes in biliary and pancreatic cancer: new application for an old drug.
Author: Bang, Sookhee|Jang, Sung Ill|Lee, Su Yeon|Baek, Yi-Yong|Yun, Jieun|Oh, Soo Jin|Lee, Chang Woo|Jo, Eun Ae|Na, Kun|Yang, Sugeun|Lee, Don Haeng|Lee, Dong Ki
PMID: 25983747
Journal: Biotechnol Prog. 2015 Jul-Aug;31(4):1071-6.
Title: Cancer stem cell marker-expressing cell-rich spheroid fabrication from PANC-1 cells using alginate microcapsules with spherical cavities templated by gelatin microparticles.
Author: Sakai, Shinji|Inamoto, Kazuya|Ashida, Tomoaki|Takamura, Ryo|Taya, Masahito
PMID: 26013961
Journal: Pancreas. 2015 Aug;44(6):918-24.
Title: Retinoic Acid Reduces Stem Cell-Like Features in Pancreatic Cancer Cells.
Author: Herreros-Villanueva, Marta|Er, Tze-Kiong|Bujanda, Luis
PMID: 26035122
Journal: Int J Cancer. 2015 Dec 1;137(11):2566-77.
Title: A self-enforcing CD44s/ZEB1 feedback loop maintains EMT and stemness properties in cancer cells.
Author: Preca, Bogdan-Tiberius|Bajdak, Karolina|Mock, Kerstin|Sundararajan, Vignesh|Pfannstiel, Jessica|Maurer, Jochen|Wellner, Ulrich|Hopt, Ulrich T|Brummer, Tilman|Brabletz, Simone|Brabletz, Thomas|Stemmler, Marc P
PMID: 26077342
Journal: Minerva Med. 2015 Aug;106(4):193-202. Epub 2015 Jun 17.
Title: MicroRNA-200c overexpression plays an inhibitory role in human pancreatic cancer stem cells by regulating epithelial-mesenchymal transition.
Author: Ma, C|Ding, Y C|Yu, W|Wang, Q|Meng, B|Huang, T
PMID: 26081037
Journal: Oncoscience. 2015 Jun 15;2(6):572-5.
Title: Targeting CD44 as a novel therapeutic approach for treating pancreatic cancer recurrence.
Author: Molejon, Maria Ines|Tellechea, Juan Ignacio|Moutardier, Vincent|Gasmi, Mohamed|Ouaissi, Mehdi|Turrini, Olivier|Delpero, Jean-Robert|Dusetti, Nelson|Iovanna, Juan
PMID: 26244163
Journal: Int J Clin Exp Pathol. 2015 Jun 1;8(6):6724-31. eCollection 2015.
Title: Expression of CD44 in pancreatic cancer and its significance.
Author: Li, Xiao-Ping|Zhang, Xiao-Wei|Zheng, Lei-Zhen|Guo, Wei-Jian
PMID: 26261555
Journal: Biomacromolecules. 2015 Sep 14;16(9):3042-53.
Title: Hyaluronic Acid Engineered Nanomicelles Loaded with 3,4-Difluorobenzylidene Curcumin for Targeted Killing of CD44+ Stem-Like Pancreatic Cancer Cells.
Author: Kesharwani, Prashant|Banerjee, Sanjeev|Padhye, Subhash|Sarkar, Fazlul H|Iyer, Arun K
PMID: 26302089
Journal: J Immunol. 2015 Oct 15;195(8):4010-9.
Title: NK Cells Preferentially Target Tumor Cells with a Cancer Stem Cell Phenotype.
Author: Ames, Erik|Canter, Robert J|Grossenbacher, Steven K|Mac, Stephanie|Chen, Mingyi|Smith, Rachel C|Hagino, Takeshi|Perez-Cunningham, Jessica|Sckisel, Gail D|Urayama, Shiro|Monjazeb, Arta M|Fragoso, Ruben C|Sayers, Thomas J|Murphy, William J
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Journal: Stem Cell Res Ther. 2015 Sep 22;6:182.
Title: Polyphenols from marine brown algae target radiotherapy-coordinated EMT and stemness-maintenance in residual pancreatic cancer.
Author: Aravindan, Sheeja|Ramraj, Satish Kumar|Somasundaram, Somasundaram T|Herman, Terence S|Aravindan, Natarajan
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Journal: Int J Oncol. 2015 Nov;47(5):1912-22.
Title: Cantharidin and norcantharidin impair stemness of pancreatic cancer cells by repressing the beta-catenin pathway and strengthen the cytotoxicity of gemcitabine and erlotinib.
Author: Wang, Wen-Jie|Wu, Meng-Yao|Shen, Meng|Zhi, Qiaoming|Liu, Ze-Yi|Gong, Fei-Ran|Tao, Min|Li, Wei
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Journal: Oncotarget. 2015 Nov 3;6(34):35931-48.
Title: Fendiline inhibits proliferation and invasion of pancreatic cancer cells by interfering with ADAM10 activation and beta-catenin signaling.
Author: Woods, Neha|Trevino, Jose|Coppola, Domenico|Chellappan, Srikumar|Yang, Shengyu|Padmanabhan, Jaya
PMID: 26440150
Journal: Colloids Surf B Biointerfaces. 2015 Dec 1;136:413-23.
Title: Hyaluronic acid-conjugated polyamidoamine dendrimers for targeted delivery of 3,4-difluorobenzylidene curcumin to CD44 overexpressing pancreatic cancer cells.
Author: Kesharwani, Prashant|Xie, Lingxiao|Banerjee, Sanjeev|Mao, Guangzhao|Padhye, Subhash|Sarkar, Fazlul H|Iyer, Arun K
PMID: 26440757
Journal: Mol Cancer. 2015 Oct 12;14:179.
Title: Blockade of autophagy reduces pancreatic cancer stem cell activity and potentiates the tumoricidal effect of gemcitabine.
Author: Yang, Ming-Chen|Wang, Hao-Chen|Hou, Ya-Chin|Tung, Hui-Ling|Chiu, Tai-Jan|Shan, Yan-Shen
PMID: 26458814
Journal: Am J Cancer Res. 2015 Aug 15;5(9):2643-59. eCollection 2015.
Title: LIN28B suppresses microRNA let-7b expression to promote CD44+/LIN28B+ human pancreatic cancer stem cell proliferation and invasion.
Author: Shao, Yebo|Zhang, Lei|Cui, Lei|Lou, Wenhui|Wang, Dansong|Lu, Weiqi|Jin, Dayong|Liu, Te
PMID: 26609473
Journal: World J Surg Oncol. 2015 Dec 15;13:334.
Title: Expression and significance of CD44 and p-AKT in pancreatic head cancer.
Author: Xiaoping, Li|Xiaowei, Zhang|Leizhen, Zheng|Weijian, Guo
PMID: 26666511
Journal: Cancer Lett. 2016 Jan 28;370(2):260-7.
Title: p-21 activated kinase 4 (PAK4) maintains stem cell-like phenotypes in pancreatic cancer cells through activation of STAT3 signaling.
Author: Tyagi, Nikhil|Marimuthu, Saravanakumar|Bhardwaj, Arun|Deshmukh, Sachin K|Srivastava, Sanjeev K|Singh, Ajay P|McClellan, Steven|Carter, James E|Singh, Seema
PMID: 26546043
Journal: Gastroenterology. 2016 Feb;150(2):513-25.e10.
Title: Inhibition of Tumor Growth and Metastasis in Pancreatic Cancer Models by Interference With CD44v6 Signaling.
Author: Matzke-Ogi, Alexandra|Jannasch, Katharina|Shatirishvili, Marine|Fuchs, Beatrix|Chiblak, Sara|Morton, Jennifer|Tawk, Bouchra|Lindner, Thomas|Sansom, Owen|Alves, Frauke|Warth, Arne|Schwager, Christian|Mier, Walter|Kleeff, Jorg|Ponta, Helmut|Abdollahi, Amir|
PMID: 26597578
Journal: Oncotarget. 2016 Jan 19;7(3):3217-32.
Title: Quinomycin A targets Notch signaling pathway in pancreatic cancer stem cells.
Author: Ponnurangam, Sivapriya|Dandawate, Prasad R|Dhar, Animesh|Tawfik, Ossama W|Parab, Rajashri R|Mishra, Prabhu Dutt|Ranadive, Prafull|Sharma, Rajiv|Mahajan, Girish|Umar, Shahid|Weir, Scott J|Sugumar, Aravind|Jensen, Roy A|Padhye, Subhash B|Balakrishnan, Arun|
PMID: 26673007
Journal: Mol Med Rep. 2016 Feb;13(2):1434-40.
Title: Reduced proliferation and increased apoptosis of the SGC7901 gastric cancer cell line on exposure to GDC0449.
Author: Wu, Chuanqing|Cheng, Ji|Hu, Shaobo|Deng, Rui|Muangu, Yamba Willy|Shi, Liang|Wu, Ke|Zhang, Peng|Chang, Weilong|Wang, Guobin|Tao, Kaixiong
PMID: 26676867
Journal: Int J Oncol. 2016 Mar;48(3):908-18.
Title: Acquired resistance of pancreatic cancer cells to treatment with gemcitabine and HER-inhibitors is accompanied by increased sensitivity to STAT3 inhibition.
Author: Ioannou, Nikolaos|Seddon, Alan M|Dalgleish, Angus|Mackintosh, David|Solca, Flavio|Modjtahedi, Helmout
PMID: 26781210
Journal: Cancer Res. 2016 Apr 15;76(8):2419-31.
Title: KLF4-Mediated Suppression of CD44 Signaling Negatively Impacts Pancreatic Cancer Stemness and Metastasis.
Author: Yan, Yongmin|Li, Zhiwei|Kong, Xiangyu|Jia, Zhiliang|Zuo, Xiangsheng|Gagea, Mihai|Huang, Suyun|Wei, Daoyan|Xie, Keping
PMID: 26880805
Journal: Sci Rep. 2016 Feb 17;6:21648.
Title: MIA PaCa-2 and PANC-1 - pancreas ductal adenocarcinoma cell lines with neuroendocrine differentiation and somatostatin receptors.
Author: Gradiz, Rui|Silva, Henriqueta C|Carvalho, Lina|Botelho, Maria Filomena|Mota-Pinto, Anabela
PMID: 26884312
Journal: Am J Pathol. 2016 Jun;186(6):1537-46.
Title: Isolation of Pancreatic Cancer Cells from a Patient-Derived Xenograft Model Allows for Practical Expansion and Preserved Heterogeneity in Culture.
Author: Pham, Kien|Delitto, Daniel|Knowlton, Andrea E|Hartlage, Emily R|Madhavan, Ricky|Gonzalo, David H|Thomas, Ryan M|Behrns, Kevin E|George, Thomas J Jr|Hughes, Steven J|Wallet, Shannon M|Liu, Chen|Trevino, Jose G
PMID: 27102771
Journal: Oncotarget. 2016 Aug 2;7(31):49156-49168.
Title: Membranous CD24 drives the epithelial phenotype of pancreatic cancer.
Author: Lubeseder-Martellato, Clara|Hidalgo-Sastre, Ana|Hartmann, Carolin|Alexandrow, Katharina|Kamyabi-Moghaddam, Zahra|Sipos, Bence|Wirth, Matthias|Neff, Florian|Reichert, Maximilian|Heid, Irina|Schneider, Gunter|Braren, Rickmer|Schmid, Roland M|Siveke, Jens T
PMID: 27203385
Journal: Clin Cancer Res. 2016 Dec 15;22(24):6069-6077.
Title: CD44 SNPrs187115: A Novel Biomarker Signature that Predicts Survival in Resectable Pancreatic Ductal Adenocarcinoma.
Author: Stracquadanio, Giovanni|Vrugt, Bart|Flury, Renata|Schraml, Peter|Wurl, Peter|Muller, Thomas H|Knippschild, Uwe|Henne-Bruns, Doris|Breitenstein, Stefan|Clavien, Pierre-Alain|Graf, Rolf|Bond, Gareth L|Grochola, Lukasz F
PMID: 27283965
Journal: Oncotarget. 2016 Jul 26;7(30):47145-47162.
Title: FH535, a beta-catenin pathway inhibitor, represses pancreatic cancer xenograft growth and angiogenesis.
Author: Liu, Lu|Zhi, Qiaoming|Shen, Meng|Gong, Fei-Ran|Zhou, Binhua P|Lian, Lian|Shen, Bairong|Chen, Kai|Duan, Weiming|Wu, Meng-Yao|Tao, Min|Li, Wei
PMID: 27323403
Journal: J Immunother Cancer. 2016 Jun 21;4:33.
Title: Pancreatic cancer stem cells in patient pancreatic xenografts are sensitive to drozitumab, an agonistic antibody against DR5.
Author: Eng, Jason W-L|Mace, Thomas A|Sharma, Rohit|Twum, Danielle Y F|Peng, Peng|Gibbs, John F|Pitoniak, Rosemarie|Reed, Chelsey B|Abrams, Scott I|Repasky, Elizabeth A|Hylander, Bonnie L
PMID: 27330806
Journal: Oncotarget. 2016 Sep 6;7(36):57783-57797.
Title: Role of SATB2 in human pancreatic cancer: Implications in transformation and a promising biomarker.
Author: Yu, Wei|Ma, Yiming|Shankar, Sharmila|Srivastava, Rakesh K
PMID: 27472393
Journal: Tumour Biol. 2016 Oct 12. pii: 10.1007/s13277-016-5461-8.
Title: Ski modulate the characteristics of pancreatic cancer stem cells via regulating sonic hedgehog signaling pathway.
Author: Song, Libin|Chen, Xiangyuan|Gao, Song|Zhang, Chenyue|Qu, Chao|Wang, Peng|Liu, Luming
PMID: 27734340
Journal: Int J Oncol. 2016 Dec;49(6):2265-2274.
Title: STAT3 as a potential therapeutic target in ALDH+ and CD44+/CD24+ stem cell-like pancreatic cancer cells.
Author: Lin, Li|Jou, David|Wang, Yina|Ma, Haiyan|Liu, Tianshu|Fuchs, James|Li, Pui-Kai|Lu, Jiagao|Li, Chenglong|Lin, Jiayuh
PMID: 27748818
Journal: Biotechnol Appl Biochem. 2017 Mar;64(2):165-173.
Title: Garcinol downregulates Notch1 signaling via modulating miR-200c and suppresses oncogenic properties of PANC-1 cancer stem-like cells.
Author: Huang, Chi-Cheng|Lin, Chien-Min|Huang, Yan-Jiun|Wei, Li|Ting, Lei-Li|Kuo, Chia-Chun|Hsu, Cheyu|Chiou, Jeng-Fong|Wu, Alexander T H|Lee, Wei-Hwa
PMID: 26400206
Journal: Pancreas. 2017 Feb;46(2):190-197.
Title: 4-Methylumbelliferone Suppresses Hyaluronan Synthesis and Tumor Progression in SCID Mice Intra-abdominally Inoculated With Pancreatic Cancer Cells.
Author: Nagase, Hayato|Kudo, Daisuke|Suto, Akiko|Yoshida, Eri|Suto, Shinichiro|Negishi, Mika|Kakizaki, Ikuko|Hakamada, Kenichi
PMID: 27846148
Journal: J Mol Recognit. 2017 Apr;30(4).
Title: The DNA aptamer binds stemness-enriched cancer cells in pancreatic cancer.
Author: Kim, Yoon-Jin|Lee, Hee Seung|Jung, Dawoon E|Kim, Jeong Mi|Song, Si Young
PMID: 27891685
Journal: Oncogene. 2017 May 11;36(19):2643-2654.
Title: FOXO3 is essential for CD44 expression in pancreatic cancer cells.
Author: Kumazoe, M|Takai, M|Bae, J|Hiroi, S|Huang, Y|Takamatsu, K|Won, Y|Yamashita, M|Hidaka, S|Yamashita, S|Yamada, S|Murata, M|Tsukamoto, S|Tachibana, H
PMID: 27893718
Journal: Oncotarget. 2017 Jan 31;8(5):7740-7752.
Title: Leptin-Notch signaling axis is involved in pancreatic cancer progression.
Author: Harbuzariu, Adriana|Rampoldi, Antonio|Daley-Brown, Danielle S|Candelaria, Pierre|Harmon, Tia L|Lipsey, Crystal C|Beech, Derrick J|Quarshie, Alexander|Ilies, Gabriela Oprea|Gonzalez-Perez, Ruben R
PMID: 27999190
Journal: J Hepatobiliary Pancreat Sci. 2017 Mar;24(3):176-184.
Title: Analysis of the origin of anaplastic pancreatic cancer and the mechanism of its dedifferentiation.
Author: Miura, Kotaro|Kimura, Kenjiro|Amano, Ryosuke|Yamazoe, Sadaaki|Ohira, Go|Nishio, Kohei|Kametani, Naoki|Hirakawa, Kosei|Ohira, Masaichi
PMID: 28064441
Journal: BMC Cancer. 2017 Apr 7;17(1):249.
Title: Inhibition of Six1 affects tumour invasion and the expression of cancer stem cell markers in pancreatic cancer.
Author: Lerbs, Tristan|Bisht, Savita|Scholch, Sebastian|Pecqueux, Mathieu|Kristiansen, Glen|Schneider, Martin|Hofmann, Bianca T|Welsch, Thilo|Reissfelder, Christoph|Rahbari, Nuh N|Fritzmann, Johannes|Brossart, Peter|Weitz, Jurgen|Feldmann, Georg|Kahlert, Christop
PMID: 28388884
Journal: Cancer Lett. 2017 Jul 10;398:24-36.
Title: Asporin promotes pancreatic cancer cell invasion and migration by regulating the epithelial-to-mesenchymal transition (EMT) through both autocrine and paracrine mechanisms.
Author: Wang, Lili|Wu, Huanwen|Wang, Li|Zhang, Hui|Lu, Junliang|Liang, Zhiyong|Liu, Tonghua
PMID: 28400334
Journal: Am J Cancer Res. 2017 Mar 1;7(3):503-517. eCollection 2017.
Title: Nodal signaling activates the Smad2/3 pathway to regulate stem cell-like properties in breast cancer cells.
Author: Gong, Wenchen|Sun, Baocun|Sun, Huizhi|Zhao, Xiulan|Zhang, Danfang|Liu, Tieju|Zhao, Nan|Gu, Qiang|Dong, Xueyi|Liu, Fang
PMID: 28401007
Journal: Sci Rep. 2017 May 10;7(1):1665.
Title: Design, Synthesis and Biological Evaluation of novel Hedgehog Inhibitors for treating Pancreatic Cancer.
Author: Kumar, Vinod|Chaudhary, Amit Kumar|Dong, Yuxiang|Zhong, Haizhen A|Mondal, Goutam|Lin, Feng|Kumar, Virender|Mahato, Ram I
PMID: 28490735
Journal: J Biol Chem. 2017 Jun 30;292(26):10813-10823.
Title: The FOXO3/PGC-1beta signaling axis is essential for cancer stem cell properties of pancreatic ductal adenocarcinoma.
Author: Kumazoe, Motofumi|Takai, Mika|Hiroi, Shun|Takeuchi, Chieri|Kadomatsu, Mai|Nojiri, Takashi|Onda, Hiroaki|Bae, Jaehoon|Huang, Yuhui|Takamatsu, Kanako|Yamashita, Shuya|Kangawa, Kenji|Tachibana, Hirofumi
PMID: 28507102
Journal: Exp Ther Med. 2017 May;13(5):2529-2536.
Title: Smoothened antagonist GDC-0449 (Vismodegib) inhibits proliferation and triggers apoptosis in colon cancer cell lines.
Author: Wu, Chuanqing|Hu, Shaobo|Cheng, Ji|Wang, Guobin|Tao, Kaixiong
PMID: 28565875
Journal: Free Radic Biol Med. 2017 Sep;110:151-161.
Title: Synthetic 8-hydroxydeoxyguanosine inhibited metastasis of pancreatic cancer through concerted inhibitions of ERM and Rho-GTPase.
Author: Park, Jong-Min|Han, Young-Min|Jeong, Migyeong|Chung, Myung Hee|Kwon, Chang Il|Ko, Kwang Hyun|Hahm, Ki Baik
PMID: 28602912
Journal: Oncol Lett. 2017 Aug;14(2):1341-1346.
Title: CD44(+)CD24(+) subset of PANC-1 cells exhibits radiation resistance via decreased levels of reactive oxygen species.
Author: Wang, Lei|Li, Pengping|Hu, Wei|Xia, Youyou|Hu, Chenxi|Liu, Liang|Jiang, Xiaodong
PMID: 28789349
Journal: World J Gastroenterol. 2017 Aug 21;23(31):5764-5772.
Title: Doublecortin and CaM kinase-like-1 as an independent prognostic factor in patients with resected pancreatic carcinoma.
Author: Nishio, Kohei|Kimura, Kenjiro|Amano, Ryosuke|Nakata, Bunzo|Yamazoe, Sadaaki|Ohira, Go|Miura, Kotaro|Kametani, Naoki|Tanaka, Hiroaki|Muguruma, Kazuya|Hirakawa, Kosei|Ohira, Masaichi
PMID: 28883702
Journal: Cancer Lett. 2017 Dec 1;410:68-81.
Title: LncRNA HOTTIP modulates cancer stem cell properties in human pancreatic cancer by regulating HOXA9.
Author: Fu, Zhiqiang|Chen, Changhao|Zhou, Quanbo|Wang, Yinxue|Zhao, Yue|Zhao, Xiaohui|Li, Wenzhu|Zheng, Shangyou|Ye, Huilin|Wang, Lin|He, Zhanghai|Lin, Qing|Li, Zhihua|Chen, Rufu
PMID: 28947139
Journal: Oncotarget. 2017 Jul 22;8(44):76398-76407.
Title: Suppression of pancreatic adenocarcinoma upregulated factor (PAUF) increases the sensitivity of pancreatic cancer to gemcitabine and 5FU, and inhibits the formation of pancreatic cancer stem like cells.
Author: Cho, Jae Hee|Kim, Sun A|Park, Soo Been|Kim, Hee Man|Song, Si Young
PMID: 29100320
Journal: J Radiat Res. 2017 Nov 1;58(6):816-826.
Title: The CD44 standard isoform contributes to radioresistance of pancreatic cancer cells.
Author: Tsubouchi, Kento|Minami, Kazumasa|Hayashi, Naoki|Yokoyama, Yuhki|Mori, Seiji|Yamamoto, Hirofumi|Koizumi, Masahiko
PMID: 29106581
Journal: Gut. 2018 Feb;67(2):320-332.
Title: IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer.
Author: Mace, Thomas A|Shakya, Reena|Pitarresi, Jason R|Swanson, Benjamin|McQuinn, Christopher W|Loftus, Shannon|Nordquist, Emily|Cruz-Monserrate, Zobeida|Yu, Lianbo|Young, Gregory|Zhong, Xiaoling|Zimmers, Teresa A|Ostrowski, Michael C|Ludwig, Thomas|Bloomston, M
PMID: 27797936
Journal: Cancer Lett. 2018 Jan 28;413:82-93.
Title: Nimbolide reduces CD44 positive cell population and induces mitochondrial apoptosis in pancreatic cancer cells.
Author: Kumar, Sandeep|Inigo, Joseph R|Kumar, Rahul|Chaudhary, Ajay K|O'Malley, Jordan|Balachandar, Srimmitha|Wang, Jianmin|Attwood, Kristopher|Yadav, Neelu|Hochwald, Steven|Wang, Xinjiang|Chandra, Dhyan
PMID: 29107110
Journal: Cancer Sci. 2018 Feb;109(2):373-383.
Title: PRDM14 directly interacts with heat shock proteins HSP90alpha and glucose-regulated protein 78.
Author: Moriya, Chiharu|Taniguchi, Hiroaki|Nagatoishi, Satoru|Igarashi, Hisayoshi|Tsumoto, Kouhei|Imai, Kohzoh
PMID: 29178343
Journal: Oncol Lett. 2018 Feb;15(2):2485-2490.
Title: Electron microscopic analysis of different cell types in human pancreatic cancer spheres.
Author: Ishiwata, Toshiyuki|Hasegawa, Fumio|Michishita, Masaki|Sasaki, Norihiko|Ishikawa, Naoshi|Takubo, Kaiyo|Matsuda, Yoko|Arai, Tomio|Aida, Junko
PMID: 29434962
Journal: J Proteome Res. 2018 Apr 6;17(4):1690-1699.
Title: Circulating Microvesicles from Pancreatic Cancer Accelerate the Migration and Proliferation of PANC-1 Cells.
Author: An, Mingrui|Zhu, Jianhui|Wu, Jing|Cuneo, Kyle C|Lubman, David M
PMID: 29494150
Journal: Anticancer Res. 2018 Apr;38(4):1937-1946.
Title: MEKK3 Sustains EMT and Stemness in Pancreatic Cancer by Regulating YAP and TAZ Transcriptional Activity.
Author: Santoro, Raffaela|Zanotto, Marco|Carbone, Carmine|Piro, Geny|Tortora, Giampaolo|Melisi, Davide
PMID: 29599309
Journal: Eur J Med Chem. 2018 May 10;151:601-627.
Title: Syntheses and anti-pancreatic cancer activities of rakicidin A analogues.
Author: Chen, Jian|Li, Jingpei|Wu, Lingling|Geng, Yan|Yu, Jianming|Chong, Chuanke|Wang, Mengmeng|Gao, Yuan|Bai, Cuigai|Ding, Yahui|Chen, Yue|Zhang, Quan
PMID: 29656202
Journal: Int J Biol Markers. 2018 Aug;33(3):308-313.
Title: CD44 overexpression related to lymph node metastasis and poor prognosis of pancreatic cancer.
Author: Liu, Yijuan|Wu, Ting|Lu, Dong|Zhen, Jiantao|Zhang, Lin
PMID: 29683068
Journal: J Cell Mol Med. 2018 May 15.
Title: Chronic ethanol exposure of human pancreatic normal ductal epithelial cells induces cancer stem cell phenotype through SATB2.
Author: Yu, Wei|Ma, Yuming|Shankar, Sharmila|Srivastava, Rakesh K
PMID: 29761897
Journal: J Cancer. 2018 May 25;9(12):2147-2159.
Title: MicroRNA-30b targets Snail to impede epithelial-mesenchymal transition in pancreatic cancer stem cells.
Author: Xiong, Yicheng|Wang, Yao|Wang, Lei|Huang, Yan|Xu, Yang|Xu, Liancheng|Guo, Yibing|Lu, Jingjing|Li, Xiaohong|Zhu, Mingyan|Qian, Haixin
PMID: 29937934
Journal: Cancers (Basel). 2018 Jun 27;10(7). pii: cancers10070217.
Title: Nano-Pulse Stimulation for the Treatment of Pancreatic Cancer and the Changes in Immune Profile.
Author: Guo, Siqi|Burcus, Niculina I|Hornef, James|Jing, Yu|Jiang, Chunqi|Heller, Richard|Beebe, Stephen J
PMID: 29954062
Journal: Integr Cancer Ther. 2018 Jul 1:1534735418786027.
Title: Extract of the Medicinal Plant Pao Pereira Inhibits Pancreatic Cancer Stem-Like Cell In Vitro and In Vivo.
Author: Dong, Ruochen|Chen, Ping|Chen, Qi
PMID: 29985062
Journal: Cancer Res. 2018 Aug 28. pii: 0008-5472.CAN-18-0634.
Title: Inverse Correlation of STAT3 and MEK Signaling Mediates Resistance to RAS Pathway Inhibition in Pancreatic Cancer.
Author: Nagathihalli, Nagaraj S|Castellanos, Jason|Lamichhane, Purushottam|Messaggio, Fanuel|Shi, Chanjuan|Dai, Xizi|Rai, Priyamvada|Chen, Xi|VanSaun, Michael N|Merchant, Nipun B
PMID: 30154150
Journal: Oncol Lett. 2018 Oct;16(4):4855-4862.
Title: Expression of Smo in pancreatic cancer CD44(+)CD24(+)cells and construction of a lentiviral expression vector to silence Smo.
Author: Cong, Peng|Yi, Chao|Wang, Xi-Yan
PMID: 30250551
Journal: J Exp Clin Cancer Res. 2018 Oct 3;37(1):240.
Title: An ABCG2 non-substrate anticancer agent FL118 targets drug-resistant cancer stem-like cells and overcomes treatment resistance of human pancreatic cancer.
Author: Ling, Xiang|Wu, Wenjie|Fan, Chuandong|Xu, Chao|Liao, Jianqun|Rich, Laurie J|Huang, Ruea-Yea|Repasky, Elizabeth A|Wang, Xinjiang|Li, Fengzhi
PMID: 30285798
Journal: Cancer Med. 2018 Oct 14.
Title: Vasohibin 2 promotes malignant behaviors of pancreatic cancer cells by inducing epithelial-mesenchymal transition via Hedgehog signaling pathway.
Author: Zhang, Ye|Xue, Xiaofeng|Zhao, Xiaoqian|Qin, Lei|Shen, Yu|Dou, Huiqiang|Sun, Jialin|Wang, Tong|Yang, Da-Qing
PMID: 30318866
Journal: J Cell Physiol. 2018 Oct 18.
Title: Combination therapy for the treatment of pancreatic cancer through hyaluronic acid-decorated nanoparticles loaded with quercetin and gemcitabine: A preliminary in vitro study.
Author: Serri, Carla|Quagliariello, Vincenzo|Iaffaioli, Rosario Vincenzo|Fusco, Sabato|Botti, Gerardo|Mayol, Laura|Biondi, Marco
PMID: 30334571