Primary Site >> Colorectal Cancer

Gene >> CCR6

Journal: Novartis Found Symp. 2004;256:241-54; discussion 254-69.
Title: In vivo manipulation of dendritic cell migration and activation to elicit antitumour immunity.
Author: Vicari, Alain P|Vanbervliet, Beatrice|Massacrier, Catherine|Chiodoni, Claudia|Vaure, Celine|Ait-Yahia, Smina|Dercamp, Christophe|Matsos, Fabien|Reynard, Olivier|Taverne, Catherine|Merle, Philippe|Colombo, Mario P|O'Garra, Anne|Trinchieri, Giorgio|Caux, Ch
PMID: 15027495
Journal: J Cell Biochem. 2006 Mar 1;97(4):709-23.
Title: Cell differentiation dependent expressed CCR6 mediates ERK-1/2, SAPK/JNK, and Akt signaling resulting in proliferation and migration of colorectal cancer cells.
Author: Brand, Stephan|Olszak, Torsten|Beigel, Florian|Diebold, Joachim|Otte, Jan-Michel|Eichhorst, Soeren T|Goke, Burkhard|Dambacher, Julia
PMID: 16215992
Journal: J Clin Oncol. 2006 Apr 20;24(12):1910-6.
Title: Chemokine receptor CCR6 expression level and liver metastases in colorectal cancer.
Author: Ghadjar, Pirus|Coupland, Sarah Ellen|Na, Il-Kang|Noutsias, Michel|Letsch, Anne|Stroux, Andrea|Bauer, Sandra|Buhr, Heinz J|Thiel, Eckhard|Scheibenbogen, Carmen|Keilholz, Ulrich
PMID: 16622267
Journal: Tumour Biol. 2006;27(3):166-74.
Title: Involvement of chemokine receptor CCR6 in colorectal cancer metastasis.
Author: Rubie, Claudia|Oliveira, Vilma|Kempf, Katja|Wagner, Mathias|Tilton, Bettina|Rau, Bettina|Kruse, Bianca|Konig, Jochen|Schilling, Martin
PMID: 16641550
Journal: World J Gastroenterol. 2006 Nov 7;12(41):6627-33.
Title: Chemokine expression in hepatocellular carcinoma versus colorectal liver metastases.
Author: Rubie, Claudia|Frick, Vilma Oliveira|Wagner, Mathias|Weber, Christina|Kruse, Bianca|Kempf, Katja|Konig, Jochen|Rau, Bettina|Schilling, Martin
PMID: 17075975
Journal: Int J Cancer. 2009 Aug 15;125(4):741-5.
Title: The chemokine CCL20 and its receptor CCR6 in human malignancy with focus on colorectal cancer.
Author: Ghadjar, Pirus|Rubie, Claudia|Aebersold, Daniel M|Keilholz, Ulrich
PMID: 19480006
Journal: J Leukoc Biol. 2011 Jan;89(1):85-91.
Title: Foxp3+IL-17+ T cells promote development of cancer-initiating cells in colorectal cancer.
Author: Yang, Shaobo|Wang, Binquan|Guan, Chunying|Wu, Benyan|Cai, Changhao|Wang, Mengwei|Zhang, Binsheng|Liu, Tao|Yang, Pingchang
PMID: 20952660
Journal: Scand J Immunol. 2011 Jul;74(1):47-51.
Title: Colorectal cancer-derived Foxp3(+) IL-17(+) T cells suppress tumour-specific CD8+ T cells.
Author: Ma, C|Dong, X
PMID: 21352252
Journal: J Immunol. 2011 Apr 1;186(7):4388-95.
Title: IL-17+ regulatory T cells in the microenvironments of chronic inflammation and cancer.
Author: Kryczek, Ilona|Wu, Ke|Zhao, Ende|Wei, Shuang|Vatan, Linhua|Szeliga, Wojciech|Huang, Emina|Greenson, Joel|Chang, Alfred|Rolinski, Jacek|Radwan, Piotr|Fang, Jingyuan|Wang, Guobin|Zou, Weiping
PMID: 21357259
Journal: PLoS One. 2011 Apr 29;6(4):e19495.
Title: Tumor-associated macrophages recruit CCR6+ regulatory T cells and promote the development of colorectal cancer via enhancing CCL20 production in mice.
Author: Liu, Jinlin|Zhang, Ning|Li, Qun|Zhang, Weiwei|Ke, Fang|Leng, Qibin|Wang, Hong|Chen, Jinfei|Wang, Honglin
PMID: 21559338
Journal: World J Gastroenterol. 2011 Jul 14;17(26):3109-16.
Title: Effect of preoperative FOLFOX chemotherapy on CCL20/CCR6 expression in colorectal liver metastases.
Author: Rubie, Claudia|Frick, Vilma Oliveira|Ghadjar, Pirus|Wagner, Mathias|Justinger, Christoph|Graeber, Stefan|Sperling, Jens|Kollmar, Otto|Schilling, Martin K
PMID: 21912453
Journal: Histopathology. 2013 Aug;63(2):167-73.
Title: The expression of chemokine receptors CCR6, CXCR2 and CXCR4 is not organ-specific for distant metastasis in colorectal cancer: a comparative study.
Author: Hu, Dongzhi|Du, Changzheng|Xue, Weicheng|Dou, Fangyuan|Yao, Yunfeng|Gu, Jin
PMID: 23758411
Journal: Scand J Immunol. 2013 Sep;78(3):298-305.
Title: CCR6/CCL20 chemokine expression profile in distinct colorectal malignancies.
Author: Frick, V O|Rubie, C|Kolsch, K|Wagner, M|Ghadjar, P|Graeber, S|Glanemann, M
PMID: 23790181
Journal: Biomed Pharmacother. 2014 Jun;68(5):551-6.
Title: Modification of chemokine receptor expression to enhance levels of trafficking receptors on autologous cytokine-induced killer cells derived from patients with colorectal cancer.
Author: Wang, Dan|Li, Jing|Liu, Jin-Yan|Li, Feng|Wang, Li-Ping|Huang, Lan|Li, Jie-Yao|Chen, Xin-Feng|Liu, Jin-Bo|Wu, Chang-Cai|Yuan, Wei-Tang|Wang, Gui-Xian|Song, Jun-Min|Yue, Dong-Li|Zhang, Zhen|Ping, Yu|Wang, Rui-Rui|Zhang, Jian-Ying|Zhang, Yi
PMID: 24855035
Journal: PLoS One. 2014 Jun 30;9(6):e101137.
Title: CCR6 is a prognostic marker for overall survival in patients with colorectal cancer, and its overexpression enhances metastasis in vivo.
Author: Liu, Jinlin|Ke, Fang|Xu, Zhenyao|Liu, Zhaoyuan|Zhang, Lingyun|Yan, Sha|Wang, Zhe|Wang, Hong|Wang, Honglin
PMID: 24979261
Journal: Tumour Biol. 2014 Sep;35(9):9355-9.
Title: Circulating follicular helper T cells in Crohn's disease (CD) and CD-associated colorectal cancer.
Author: Wang, Zhenlong|Wang, Zhiming|Diao, Yanqing|Qian, Xiaoli|Zhu, Nan|Dong, Wen
PMID: 24943684
Journal: PLoS One. 2014 May 27;9(5):e97566.
Title: CCR6, the sole receptor for the chemokine CCL20, promotes spontaneous intestinal tumorigenesis.
Author: Nandi, Bisweswar|Pai, Christine|Huang, Qin|Prabhala, Rao H|Munshi, Nikhil C|Gold, Jason S
PMID: 24866282
Journal: Immunity. 2014 May 15;40(5):772-84.
Title: IL-22(+)CD4(+) T cells promote colorectal cancer stemness via STAT3 transcription factor activation and induction of the methyltransferase DOT1L.
Author: Kryczek, Ilona|Lin, Yanwei|Nagarsheth, Nisha|Peng, Dongjun|Zhao, Lili|Zhao, Ende|Vatan, Linda|Szeliga, Wojciech|Dou, Yali|Owens, Scott|Zgodzinski, Witold|Majewski, Marek|Wallner, Grzegorz|Fang, Jingyuan|Huang, Emina|Zou, Weiping
PMID: 24816405
Journal: J Transl Med. 2014 Feb 21;12:48.
Title: Chemokine receptor CCR6 expression is regulated by miR-518a-5p in colorectal cancer cells.
Author: Rubie, Claudia|Kruse, Bianca|Frick, Vilma Oliveira|Kolsch, Kathrin|Ghadjar, Pirus|Wagner, Mathias|Grasser, Friedrich|Wagenpfeil, Stefan|Glanemann, Mathias
PMID: 24559209
Journal: J Cell Physiol. 2015 Jul;230(7):1430-7.
Title: Interleukin-17 induces CC chemokine receptor 6 expression and cell migration in colorectal cancer cells.
Author: Chin, Chih-Chien|Chen, Cheng-Nan|Kuo, Hsing-Chun|Shi, Chung-Sheng|Hsieh, Meng Chiao|Kuo, Yi-Hung|Tung, Shui-Yi|Lee, Kam-Fai|Huang, Wen-Shih
PMID: 25201147
Journal: J Immunol. 2015 Oct 1;195(7):3472-81.
Title: Human Mucosa-Associated Invariant T Cells Accumulate in Colon Adenocarcinomas but Produce Reduced Amounts of IFN-gamma.
Author: Sundstrom, Patrik|Ahlmanner, Filip|Akeus, Paulina|Sundquist, Malin|Alsen, Samuel|Yrlid, Ulf|Borjesson, Lars|Sjoling, Asa|Gustavsson, Bengt|Wong, S B Justin|Quiding-Jarbrink, Marianne
PMID: 26297765
Journal: Tumour Biol. 2016 Jan;37(1):1349-56.
Title: IL-22 promotes the proliferation of cancer cells in smoking colorectal cancer patients.
Author: Song, Bao|Ma, Yuan|Liu, Xiuchun|Li, Wanhu|Zhang, Jianbo|Liu, Jie|Han, Jinxiang
PMID: 26293897
Journal: World J Gastroenterol. 2016 Jan 14;22(2):833-41.
Title: Chemokine/chemokine receptor pair CCL20/CCR6 in human colorectal malignancy: An overview.
Author: Frick, Vilma Oliveira|Rubie, Claudia|Keilholz, Ulrich|Ghadjar, Pirus
PMID: 26811629
Journal: Br J Cancer. 2016 Jun 14;114(12):1343-51.
Title: CCR6 expression in colon cancer is associated with advanced disease and supports epithelial-to-mesenchymal transition.
Author: Kapur, Neeraj|Mir, Hina|Clark Iii, Clarence E|Krishnamurti, Uma|Beech, Derrick J|Lillard, James W|Singh, Shailesh
PMID: 27149649
Journal: Tumour Biol. 2016 Sep;37(9):12223-12230.
Title: Feedback mechanisms between M2 macrophages and Th17 cells in colorectal cancer patients.
Author: Mao, Hui|Pan, Fei|Guo, Hongxia|Bu, Fangfang|Xin, Tong|Chen, Shukun|Guo, Yajun
PMID: 27235120
Journal: Oncotarget. 2016 Nov 15;7(46):76274-76290.
Title: Clinical relevance of circulating mucosal-associated invariant T cell levels and their anti-cancer activity in patients with mucosal-associated cancer.
Author: Won, Eun Jeong|Ju, Jae Kyun|Cho, Young-Nan|Jin, Hye-Mi|Park, Ki-Jeong|Kim, Tae-Jong|Kwon, Yong-Soo|Kee, Hae Jin|Kim, Jung-Chul|Kee, Seung-Jung|Park, Yong-Wook
PMID: 27517754
Journal: Oncoimmunology. 2016 May 24;5(8):e1189052.
Title: Stromal CCR6 drives tumor growth in a murine transplantable colon cancer through recruitment of tumor-promoting macrophages.
Author: Nandi, Bisweswar|Shapiro, Mia|Samur, Mehmet K|Pai, Christine|Frank, Natasha Y|Yoon, Charles|Prabhala, Rao H|Munshi, Nikhil C|Gold, Jason S
PMID: 27622061
Journal: Gut. 2017 Apr;66(4):692-704.
Title: Dual role of tumour-infiltrating T helper 17 cells in human colorectal cancer.
Author: Amicarella, F|Muraro, M G|Hirt, C|Cremonesi, E|Padovan, E|Mele, V|Governa, V|Han, J|Huber, X|Droeser, R A|Zuber, M|Adamina, M|Bolli, M|Rosso, R|Lugli, A|Zlobec, I|Terracciano, L|Tornillo, L|Zajac, P|Eppenberger-Castori, S|Trapani, F|Oertli, D|Iezzi, G
PMID: 26719303
Journal: Cancer Res Treat. 2017 Dec 21. pii: crt.2017.538.
Title: CCR6 Is a Predicting Biomarker of Radiosensitivity and Potential Target of Radiosensitization in Rectal Cancer.
Author: Chang, Hui|Wei, Jia-Wang|Tao, Ya-Lan|Ding, Pei-Rong|Xia, Yun-Fei|Gao, Yuan-Hong|Xiao, Wei-Wei
PMID: 29268566
Journal: Biochim Biophys Acta Mol Basis Dis. 2018 Feb;1864(2):387-397.
Title: CCR6 promotes tumor angiogenesis via the AKT/NF-kappaB/VEGF pathway in colorectal cancer.
Author: Zhu, Cong-Cong|Chen, Chun|Xu, Zhuo-Qing|Zhao, Jing-Kun|Ou, Bao-Chi|Sun, Jing|Zheng, Min-Hua|Zong, Ya-Ping|Lu, Ai-Guo
PMID: 29097259