Primary Site >> Colorectal Cancer

Gene >> CCR6

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Ref: In vivo manipulation of dendritic cell migration and activation to elicit antitumour immunity.
PMID: 15027495
Ref: Cell differentiation dependent expressed CCR6 mediates ERK-1/2, SAPK/JNK, and Akt signaling resulting in proliferation and migration of colorectal cancer cells.
PMID: 16215992
Ref: Chemokine receptor CCR6 expression level and liver metastases in colorectal cancer.
PMID: 16622267
Ref: Involvement of chemokine receptor CCR6 in colorectal cancer metastasis.
PMID: 16641550
Ref: Chemokine expression in hepatocellular carcinoma versus colorectal liver metastases.
PMID: 17075975
Ref: The chemokine CCL20 and its receptor CCR6 in human malignancy with focus on colorectal cancer.
PMID: 19480006
Ref: Foxp3+IL-17+ T cells promote development of cancer-initiating cells in colorectal cancer.
PMID: 20952660
Ref: Colorectal cancer-derived Foxp3(+) IL-17(+) T cells suppress tumour-specific CD8+ T cells.
PMID: 21352252
Ref: IL-17+ regulatory T cells in the microenvironments of chronic inflammation and cancer.
PMID: 21357259
Ref: Tumor-associated macrophages recruit CCR6+ regulatory T cells and promote the development of colorectal cancer via enhancing CCL20 production in mice.
PMID: 21559338
Ref: Effect of preoperative FOLFOX chemotherapy on CCL20/CCR6 expression in colorectal liver metastases.
PMID: 21912453
Ref: The expression of chemokine receptors CCR6, CXCR2 and CXCR4 is not organ-specific for distant metastasis in colorectal cancer: a comparative study.
PMID: 23758411
Ref: CCR6/CCL20 chemokine expression profile in distinct colorectal malignancies.
PMID: 23790181
Ref: Chemokine receptor CCR6 expression is regulated by miR-518a-5p in colorectal cancer cells.
PMID: 24559209
Ref: IL-22(+)CD4(+) T cells promote colorectal cancer stemness via STAT3 transcription factor activation and induction of the methyltransferase DOT1L.
PMID: 24816405
Ref: Modification of chemokine receptor expression to enhance levels of trafficking receptors on autologous cytokine-induced killer cells derived from patients with colorectal cancer.
PMID: 24855035
Ref: CCR6, the sole receptor for the chemokine CCL20, promotes spontaneous intestinal tumorigenesis.
PMID: 24866282
Ref: Circulating follicular helper T cells in Crohn's disease (CD) and CD-associated colorectal cancer.
PMID: 24943684
Ref: CCR6 is a prognostic marker for overall survival in patients with colorectal cancer, and its overexpression enhances metastasis in vivo.
PMID: 24979261
Ref: Interleukin-17 induces CC chemokine receptor 6 expression and cell migration in colorectal cancer cells.
PMID: 25201147
Ref: Human Mucosa-Associated Invariant T Cells Accumulate in Colon Adenocarcinomas but Produce Reduced Amounts of IFN-gamma.
PMID: 26297765
Ref: IL-22 promotes the proliferation of cancer cells in smoking colorectal cancer patients.
PMID: 26293897
Ref: Chemokine/chemokine receptor pair CCL20/CCR6 in human colorectal malignancy: An overview.
PMID: 26811629
Ref: CCR6 expression in colon cancer is associated with advanced disease and supports epithelial-to-mesenchymal transition.
PMID: 27149649
Ref: Feedback mechanisms between M2 macrophages and Th17 cells in colorectal cancer patients.
PMID: 27235120
Ref: Clinical relevance of circulating mucosal-associated invariant T cell levels and their anti-cancer activity in patients with mucosal-associated cancer.
PMID: 27517754
Ref: Stromal CCR6 drives tumor growth in a murine transplantable colon cancer through recruitment of tumor-promoting macrophages.
PMID: 27622061
Ref: Dual role of tumour-infiltrating T helper 17 cells in human colorectal cancer.
PMID: 26719303
Ref: CCR6 Is a Predicting Biomarker of Radiosensitivity and Potential Target of Radiosensitization in Rectal Cancer.
PMID: 29268566
Ref: CCR6 promotes tumor angiogenesis via the AKT/NF-kappaB/VEGF pathway in colorectal cancer.
PMID: 29097259