Primary Site >> Liver Cancer

Gene >> CCR2

Journal: Gastroenterology. 2005 Dec;129(6):2064-75.
Title: Liver gene expression signature of mild fibrosis in patients with chronic hepatitis C.
Author: Asselah, Tarik|Bieche, Ivan|Laurendeau, Ingrid|Paradis, Valerie|Vidaud, Dominique|Degott, Claude|Martinot, Michelle|Bedossa, Pierre|Valla, Dominique|Vidaud, Michel|Marcellin, Patrick
PMID: 16344072
Journal: Virology. 2005 Feb 5;332(1):130-44.
Title: Molecular profiling of early stage liver fibrosis in patients with chronic hepatitis C virus infection.
Author: Bieche, Ivan|Asselah, Tarik|Laurendeau, Ingrid|Vidaud, Dominique|Degot, Claude|Paradis, Valerie|Bedossa, Pierre|Valla, Dominique-Charles|Marcellin, Patrick|Vidaud, Michel
PMID: 15661146
Journal: Int J Cancer. 2006 Jan 15;118(2):335-45.
Title: Attenuated liver tumor formation in the absence of CCR2 with a concomitant reduction in the accumulation of hepatic stellate cells, macrophages and neovascularization.
Author: Yang, Xiaoqin|Lu, Peirong|Ishida, Yuko|Kuziel, William A|Fujii, Chifumi|Mukaida, Naofumi
PMID: 16052523
Journal: Zhonghua Gan Zang Bing Za Zhi. 2007 Apr;15(4):261-5.
Title: [Different expressions of chemokine receptors in human hepatocellular carcinoma cell lines with different metastatic potentials].
Author: Xue, Tong-chun|Chen, Rong-xin|Ye, Sheng-long|Sun, Ru-xia|Chen, Jie|Tang, Zhao-you
PMID: 17456312
Journal: Zhonghua Gan Zang Bing Za Zhi. 2009 Jul;17(7):553-4.
Title: [Expression of MCP/CCR2 in patients of hepatocellular carcinoma and liver cirrhosis].
Author: Fang, Nian|Fan, Xu|Zhang, Xian-sen
PMID: 19912695
Journal: Int J Cancer. 2010 Mar 1;126(5):1095-108.
Title: Monocyte chemoattractant protein-1 (MCP-1)/CCL2 secreted by hepatic myofibroblasts promotes migration and invasion of human hepatoma cells.
Author: Dagouassat, Maylis|Suffee, Nadine|Hlawaty, Hanna|Haddad, Oualid|Charni, Faten|Laguillier, Christelle|Vassy, Roger|Martin, Loic|Schischmanoff, Pierre-Olivier|Gattegno, Liliane|Oudar, Olivier|Sutton, Angela|Charnaux, Nathalie
PMID: 19642141
Journal: J Hepatol. 2010 Mar;52(3):370-9.
Title: Inflammatory tumour microenvironment is associated with superior survival in hepatocellular carcinoma patients.
Author: Chew, Valerie|Tow, Charlene|Teo, Marissa|Wong, Hing Lok|Chan, Jasmine|Gehring, Adam|Loh, Marie|Bolze, Alexandre|Quek, Richard|Lee, Victor K M|Lee, Kang Hoe|Abastado, Jean-Pierre|Toh, Han Chong|Nardin, Alessandra
PMID: 19720422
Journal: Oncol Rep. 2012 Aug;28(2):689-94.
Title: CC chemokine ligand 7 expression in liver metastasis of colorectal cancer.
Author: Cho, Yong Beom|Lee, Woo Yong|Choi, So-Jung|Kim, Jhingook|Hong, Hye Kyung|Kim, Seok-Hyung|Choi, Yoon-La|Kim, Hee Cheol|Yun, Seong Hyeon|Chun, Ho-Kyung|Lee, Kuhn Uk
PMID: 22614322
Journal: Hepatology. 2013 Feb;57(2):829-39.
Title: Recruitment of a myeloid cell subset (CD11b/Gr1 mid) via CCL2/CCR2 promotes the development of colorectal cancer liver metastasis.
Author: Zhao, Lei|Lim, Su Yin|Gordon-Weeks, Alex N|Tapmeier, Thomas T|Im, Jae Hong|Cao, Yunhong|Beech, John|Allen, Danny|Smart, Sean|Muschel, Ruth J
PMID: 23081697
Journal: Eur J Cancer. 2014 Mar;50(5):928-36.
Title: A blood-based three-gene signature for the non-invasive detection of early human hepatocellular carcinoma.
Author: Shi, Ming|Chen, Min-Shan|Sekar, Karthik|Tan, Chee-Kiat|Ooi, London Lucien|Hui, Kam M
PMID: 24332572
Journal: J Surg Oncol. 2014 Dec;110(7):786-90.
Title: Cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy in patients with peritoneal hepatocellular carcinoma.
Author: Tabrizian, Parissa|Franssen, Bernardo|Jibara, Ghalib|Sweeney, Robert|Sarpel, Umut|Schwartz, Myron|Labow, Daniel
PMID: 25091997
Journal: Int Immunopharmacol. 2015 Jun;26(2):314-21.
Title: Subsets of myeloid-derived suppressor cells in hepatocellular carcinoma express chemokines and chemokine receptors differentially.
Author: Zhao, Wenxiu|Xu, Yaping|Xu, Jianfeng|Wu, Duan|Zhao, Bixing|Yin, Zhenyu|Wang, Xiaomin
PMID: 25891236
Journal: Cancer Res. 2016 Jul 15;76(14):4124-35.
Title: FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3-CCL2 Signaling.
Author: Yang, Xuguang|Lin, Yuli|Shi, Yinghong|Li, Bingji|Liu, Weiren|Yin, Wei|Dang, Yongjun|Chu, Yiwei|Fan, Jia|He, Rui
PMID: 27216177
Journal: Cancer Cell. 2016 Oct 10;30(4):533-547.
Title: Distinct Functions of Senescence-Associated Immune Responses in Liver Tumor Surveillance and Tumor Progression.
Author: Eggert, Tobias|Wolter, Katharina|Ji, Juling|Ma, Chi|Yevsa, Tetyana|Klotz, Sabrina|Medina-Echeverz, Jose|Longerich, Thomas|Forgues, Marshonna|Reisinger, Florian|Heikenwalder, Mathias|Wang, Xin Wei|Zender, Lars|Greten, Tim F
PMID: 27728804
Journal: Gut. 2017 Jan;66(1):157-167.
Title: Targeting of tumour-infiltrating macrophages via CCL2/CCR2 signalling as a therapeutic strategy against hepatocellular carcinoma.
Author: Li, Xiaoguang|Yao, Wenbo|Yuan, Ya|Chen, Peizhan|Li, Bin|Li, Jingquan|Chu, Ruiai|Song, Haiyun|Xie, Dong|Jiang, Xiaoqing|Wang, Hui
PMID: 26452628
Journal: Mol Cancer Ther. 2017 Feb;16(2):312-322.
Title: Blocking the CCL2-CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model.
Author: Teng, Kun-Yu|Han, Jianfeng|Zhang, Xiaoli|Hsu, Shu-Hao|He, Shun|Wani, Nissar A|Barajas, Juan M|Snyder, Linda A|Frankel, Wendy L|Caligiuri, Michael A|Jacob, Samson T|Yu, Jianhua|Ghoshal, Kalpana
PMID: 27980102
Journal: Cancer Lett. 2017 Sep 28;404:19-28.
Title: Peri-tumor associated fibroblasts promote intrahepatic metastasis of hepatocellular carcinoma by recruiting cancer stem cells.
Author: Jiang, Jinghua|Ye, Fei|Yang, Xue|Zong, Chen|Gao, Lu|Yang, Yang|Zhao, Qiudong|Han, Zhipeng|Wei, Lixin
PMID: 28716525
Journal: EBioMedicine. 2017 Aug;22:58-67.
Title: A Natural CCR2 Antagonist Relieves Tumor-associated Macrophage-mediated Immunosuppression to Produce a Therapeutic Effect for Liver Cancer.
Author: Yao, Wenbo|Ba, Qian|Li, Xiaoguang|Li, Huiliang|Zhang, Shoude|Yuan, Ya|Wang, Feng|Duan, Xiaohua|Li, Jingquan|Zhang, Weidong|Wang, Hui
PMID: 28754304
Journal: J Immunol. 2018 Mar 1;200(5):1839-1852.
Title: Alveolar Macrophages Drive Hepatocellular Carcinoma Lung Metastasis by Generating Leukotriene B4.
Author: Nosaka, Takuto|Baba, Tomohisa|Tanabe, Yamato|Sasaki, Soichiro|Nishimura, Tatsunori|Imamura, Yoshiaki|Yurino, Hideaki|Hashimoto, Shinichi|Arita, Makoto|Nakamoto, Yasunari|Mukaida, Naofumi
PMID: 29378914
Journal: Oncoimmunology. 2017 Dec 13;7(3):e1408745.
Title: Monocytes/Macrophages promote vascular CXCR4 expression via the ERK pathway in hepatocellular carcinoma.
Author: Meng, Ya-Ming|Liang, Jing|Wu, Chong|Xu, Jing|Zeng, Dan-Ni|Yu, Xing-Juan|Ning, Huiheng|Xu, Li|Zheng, Limin
PMID: 29399411
Journal: PLoS One. 2018 May 30;13(5):e0194568.
Title: Gemcabene downregulates inflammatory, lipid-altering and cell-signaling genes in the STAM model of NASH.
Author: Oniciu, Daniela Carmen|Hashiguchi, Taishi|Shibazaki, Yuichiro|Bisgaier, Charles L
PMID: 29847555
Journal: Oncoimmunology. 2018 Aug 1;7(9):e1470729.
Title: Recruitment of CCR2(+) tumor associated macrophage to sites of liver metastasis confers a poor prognosis in human colorectal cancer.
Author: Grossman, Julie G|Nywening, Timothy M|Belt, Brian A|Panni, Roheena Z|Krasnick, Bradley A|DeNardo, David G|Hawkins, William G|Goedegebuure, S Peter|Linehan, David C|Fields, Ryan C
PMID: 30228938
Journal: Expert Rev Gastroenterol Hepatol. 2018 Sep 27:1-10.
Title: An update on the recent advances in antifibrotic therapy.
Author: Tacke, Frank|Weiskirchen, Ralf
PMID: 30261763