Primary Site >> Liver Cancer

Gene >> CCR2

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Ref: Molecular profiling of early stage liver fibrosis in patients with chronic hepatitis C virus infection.
PMID: 15661146
Ref: Liver gene expression signature of mild fibrosis in patients with chronic hepatitis C.
PMID: 16344072
Ref: Attenuated liver tumor formation in the absence of CCR2 with a concomitant reduction in the accumulation of hepatic stellate cells, macrophages and neovascularization.
PMID: 16052523
Ref: [Different expressions of chemokine receptors in human hepatocellular carcinoma cell lines with different metastatic potentials].
PMID: 17456312
Ref: [Expression of MCP/CCR2 in patients of hepatocellular carcinoma and liver cirrhosis].
PMID: 19912695
Ref: Monocyte chemoattractant protein-1 (MCP-1)/CCL2 secreted by hepatic myofibroblasts promotes migration and invasion of human hepatoma cells.
PMID: 19642141
Ref: Inflammatory tumour microenvironment is associated with superior survival in hepatocellular carcinoma patients.
PMID: 19720422
Ref: CC chemokine ligand 7 expression in liver metastasis of colorectal cancer.
PMID: 22614322
Ref: Recruitment of a myeloid cell subset (CD11b/Gr1 mid) via CCL2/CCR2 promotes the development of colorectal cancer liver metastasis.
PMID: 23081697
Ref: A blood-based three-gene signature for the non-invasive detection of early human hepatocellular carcinoma.
PMID: 24332572
Ref: Cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy in patients with peritoneal hepatocellular carcinoma.
PMID: 25091997
Ref: Subsets of myeloid-derived suppressor cells in hepatocellular carcinoma express chemokines and chemokine receptors differentially.
PMID: 25891236
Ref: FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3-CCL2 Signaling.
PMID: 27216177
Ref: Distinct Functions of Senescence-Associated Immune Responses in Liver Tumor Surveillance and Tumor Progression.
PMID: 27728804
Ref: Targeting of tumour-infiltrating macrophages via CCL2/CCR2 signalling as a therapeutic strategy against hepatocellular carcinoma.
PMID: 26452628
Ref: Blocking the CCL2-CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model.
PMID: 27980102
Ref: Peri-tumor associated fibroblasts promote intrahepatic metastasis of hepatocellular carcinoma by recruiting cancer stem cells.
PMID: 28716525
Ref: A Natural CCR2 Antagonist Relieves Tumor-associated Macrophage-mediated Immunosuppression to Produce a Therapeutic Effect for Liver Cancer.
PMID: 28754304
Ref: Alveolar Macrophages Drive Hepatocellular Carcinoma Lung Metastasis by Generating Leukotriene B4.
PMID: 29378914
Ref: Monocytes/Macrophages promote vascular CXCR4 expression via the ERK pathway in hepatocellular carcinoma.
PMID: 29399411
Ref: Gemcabene downregulates inflammatory, lipid-altering and cell-signaling genes in the STAM model of NASH.
PMID: 29847555
Ref: Recruitment of CCR2(+) tumor associated macrophage to sites of liver metastasis confers a poor prognosis in human colorectal cancer.
PMID: 30228938
Ref: An update on the recent advances in antifibrotic therapy.
PMID: 30261763