Primary Site >> Colorectal Cancer

Gene >> CCNC

Journal: J Clin Pathol. 2005 May;58(5):509-14.
Title: Expression and gene amplification of primary (A, B1, D1, D3, and E) and secondary (C and H) cyclins in colon adenocarcinomas and correlation with patient outcome.
Author: Bondi, J|Husdal, A|Bukholm, G|Nesland, J M|Bakka, A|Bukholm, I R K
PMID: 15858123
Journal: Neoplasia. 2010 May;12(5):415-24.
Title: Silibinin suppresses growth of human colorectal carcinoma SW480 cells in culture and xenograft through down-regulation of beta-catenin-dependent signaling.
Author: Kaur, Manjinder|Velmurugan, Balaiya|Tyagi, Alpna|Agarwal, Chapla|Singh, Rana P|Agarwal, Rajesh
PMID: 20454513
Journal: J Genet Genomics. 2011 Oct 20;38(10):439-52.
Title: Dysregulation of CDK8 and Cyclin C in tumorigenesis.
Author: Xu, Wu|Ji, Jun-Yuan
PMID: 22035865
Journal: J Virol. 2012 May;86(10):5742-51.
Title: Retroviral cyclin enhances cyclin-dependent kinase-8 activity.
Author: Rovnak, Joel|Brewster, Connie D|Quackenbush, Sandra L
PMID: 22379099
Journal: Hum Mutat. 2014 Sep;35(9):1136-41.
Title: Mutations in Exon 1 highlight the role of MED12 in uterine leiomyomas.
Author: Kampjarvi, Kati|Park, Min Ju|Mehine, Miika|Kim, Nam Hee|Clark, Alison D|Butzow, Ralf|Bohling, Tom|Bohm, Jan|Mecklin, Jukka-Pekka|Jarvinen, Heikki|Tomlinson, Ian P M|van der Spuy, Zephne M|Sjoberg, Jari|Boyer, Thomas G|Vahteristo, Pia
PMID: 24980722
Journal: ACS Med Chem Lett. 2016 Jan 6;7(3):223-8.
Title: Development of a Potent, Specific CDK8 Kinase Inhibitor Which Phenocopies CDK8/19 Knockout Cells.
Author: Koehler, Michael F T|Bergeron, Philippe|Blackwood, Elizabeth M|Bowman, Krista|Clark, Kevin R|Firestein, Ron|Kiefer, James R|Maskos, Klaus|McCleland, Mark L|Orren, Linda|Salphati, Laurent|Schmidt, Steve|Schneider, Elisabeth V|Wu, Jiansheng|Beresini, Mauree
PMID: 26985305
Journal: J Biol Chem. 2018 Mar 30;293(13):4870-4882.
Title: Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19.
Author: Park, Min Ju|Shen, Hailian|Spaeth, Jason M|Tolvanen, Jaana H|Failor, Courtney|Knudtson, Jennifer F|McLaughlin, Jessica|Halder, Sunil K|Yang, Qiwei|Bulun, Serdar E|Al-Hendy, Ayman|Schenken, Robert S|Aaltonen, Lauri A|Boyer, Thomas G
PMID: 29440396
Journal: J Comput Aided Mol Des. 2018 Jun;32(6):671-685.
Title: A molecular dynamics investigation of CDK8/CycC and ligand binding: conformational flexibility and implication in drug discovery.
Author: Cholko, Timothy|Chen, Wei|Tang, Zhiye|Chang, Chia-En A
PMID: 29737445