Primary Site >> Colorectal Cancer

Gene >> CCL2

Journal: Cancer Res. 1988 Mar 1;48(5):1086-90.
Title: Sensitization of nitrosourea-resistant Mer+ human tumor cells to N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea by mild (41 degrees C) hyperthermia.
Author: Mulcahy, R T|Gipp, J J|Tanner, M A
PMID: 3342391
Journal: Cancer Immunol Immunother. 1994 Oct;39(4):231-8.
Title: Expression of the JE/MCP-1 gene suppresses metastatic potential in murine colon carcinoma cells.
Author: Huang, S|Singh, R K|Xie, K|Gutman, M|Berry, K K|Bucana, C D|Fidler, I J|Bar-Eli, M
PMID: 7954525
Journal: J Interferon Cytokine Res. 1995 Jul;15(7):655-65.
Title: Suppression of tumor growth and metastasis of murine renal adenocarcinoma by syngeneic fibroblasts genetically engineered to secrete the JE/MCP-1 cytokine.
Author: Huang, S|Xie, K|Singh, R K|Gutman, M|Bar-Eli, M
PMID: 7553238
Journal: Int J Oncol. 1997 Mar;10(3):481-6.
Title: Effects of thymic peptides, in vitro, on the impaired immunocytotoxicity of peripheral blood mononuclear cells from tumor patients.
Author: Eckert, K|Mayer, G|Stange, R|Kalden, M|Krasagakis, K|Maurer, H
PMID: 21533400
Journal: Cytokine. 2000 Aug;12(8):1284-7.
Title: Lens culinaris, Phaseolus vulgaris and vicia faba lectins specifically trigger IL-8 production by the human colon carcinoma cell line CACO-2.
Author: Rodriguez-Juan, C|Perez-Blas, M|Suarez-Garcia, E|Lopez-Suarez, J C|Muzquiz, M|Cuadrado, C|Martin-Villa, J M
PMID: 10930314
Journal: Neoplasma. 2004;51(4):239-47.
Title: NF-kappaB, macrophage migration inhibitory factor and cyclooxygenase-inhibitions as likely mechanisms behind the acetaminophen- and NSAID-prevention of the ovarian cancer.
Author: Altinoz, M A|Korkmaz, R
PMID: 15254653
Journal: Neoplasia. 2004 Sep-Oct;6(5):523-8.
Title: Cytokines and chemokines are expressed at different levels in small and large murine colon-26 tumors following intratumoral injections of CpG ODN.
Author: Sharma, Sanjay|Karakousis, Constantine P|Takita, Hiroshi|Shin, Kyu|Brooks, Stephen P
PMID: 15548360
Journal: Int J Oncol. 2006 Mar;28(3):695-704.
Title: Inhibition of NF-kappaB activation and chemokine expression by the leukocyte glycoprotein, CD43, in colon cancer cells.
Author: Laos, Sirle|Baeckstrom, Dan|Hansson, Gunnar C
PMID: 16465375
Journal: Regul Pept. 2006 May 15;134(2-3):105-13.
Title: Adiponectin stimulates proliferation and cytokine secretion in colonic epithelial cells.
Author: Ogunwobi, Olorunseun Olatunji|Beales, Ian L P
PMID: 16529829
Journal: J Negat Results Biomed. 2006 Oct 24;5:15.
Title: Polymorphisms within inflammatory genes and colorectal cancer.
Author: Landi, Stefano|Gemignani, Federica|Bottari, Fabio|Gioia-Patricola, Lydie|Guino, Elisabet|Cambray, Maria|Biondo, Sebastiano|Capella, Gabriel|Boldrini, Laura|Canzian, Federico|Moreno, Victor
PMID: 17062130
Journal: Gastroenterology. 2007 Jul;133(1):108-23.
Title: Fenofibrate represses interleukin-17 and interferon-gamma expression and improves colitis in interleukin-10-deficient mice.
Author: Lee, Jimmy W|Bajwa, Poonam J|Carson, Monica J|Jeske, Daniel R|Cong, Yingzi|Elson, Charles O|Lytle, Christian|Straus, Daniel S
PMID: 17631136
Journal: Clin Cancer Res. 2007 Oct 1;13(19):5719-28.
Title: Eotaxin-2 and colorectal cancer: a potential target for immune therapy.
Author: Cheadle, Eleanor J|Riyad, Kallingal|Subar, Daren|Rothwell, Dominic G|Ashton, Garry|Batha, Hayley|Sherlock, David J|Hawkins, Robert E|Gilham, David E
PMID: 17908961
Journal: Clin Exp Metastasis. 2007;24(2):121-30. Epub 2007 Mar 28.
Title: Chemokine expression is associated with the accumulation of tumour associated macrophages (TAMs) and progression in human colorectal cancer.
Author: Bailey, Charles|Negus, Rupert|Morris, Alistair|Ziprin, Paul|Goldin, Robert|Allavena, Paola|Peck, David|Darzi, Ara
PMID: 17390111
Journal: Dis Colon Rectum. 2008 Dec;51(12):1800-5.
Title: Decreased expression of monocyte chemoattractant protein-1 predicts poor prognosis following curative resection of colorectal cancer.
Author: Watanabe, Hideki|Miki, Chikao|Okugawa, Yoshinaga|Toiyama, Yuji|Inoue, Yasuhiro|Kusunoki, Masato
PMID: 18633677
Journal: Cancer Sci. 2008 Oct;99(10):2075-82.
Title: Optimal amount of monocyte chemoattractant protein-1 enhances antitumor effects of suicide gene therapy against hepatocellular carcinoma by M1 macrophage activation.
Author: Tsuchiyama, Tomoya|Nakamoto, Yasunari|Sakai, Yoshio|Mukaida, Naofumi|Kaneko, Shuichi
PMID: 19016769
Journal: Inflamm Bowel Dis. 2009 Jul;15(7):997-1006.
Title: Innate immune signaling by Toll-like receptor-4 (TLR4) shapes the inflammatory microenvironment in colitis-associated tumors.
Author: Fukata, Masayuki|Hernandez, Yasmin|Conduah, Daisy|Cohen, Jason|Chen, Anli|Breglio, Keith|Goo, Tyralee|Hsu, David|Xu, Ruliang|Abreu, Maria T
PMID: 19229991
Journal: Curr Mol Med. 2009 Jun;9(5):565-79.
Title: Role of lipoxins and resolvins as anti-inflammatory and proresolving mediators in colon cancer.
Author: Janakiram, Naveena B|Rao, Chinthalapally V
PMID: 19601807
Journal: Clin Cancer Res. 2009 Sep 1;15(17):5485-93.
Title: Tumor cell-microenvironment interaction models coupled with clinical validation reveal CCL2 and SNCG as two predictors of colorectal cancer hepatic metastasis.
Author: Hu, Hai|Sun, Lichao|Guo, Chunguang|Liu, Qian|Zhou, Zhuan|Peng, Liang|Pan, Jian|Yu, Long|Lou, Jinning|Yang, Zhihua|Zhao, Ping|Ran, Yuliang
PMID: 19706805
Journal: Cancer Res. 2009 Oct 1;69(19):7884-92.
Title: Blockade of a chemokine, CCL2, reduces chronic colitis-associated carcinogenesis in mice.
Author: Popivanova, Boryana Konstantinova|Kostadinova, Feodora Ivanova|Furuichi, Kengo|Shamekh, Mohamed M|Kondo, Toshikazu|Wada, Takashi|Egashira, Kensuke|Mukaida, Naofumi
PMID: 19773434
Journal: Chem Biol Interact. 2010 Mar 30;184(3):423-30.
Title: Genetic ablation of Tnfalpha demonstrates no detectable suppressive effect on inflammation-related mouse colon tumorigenesis.
Author: Sakai, Hiroyasu|Yamada, Yasuhiro|Shimizu, Masahito|Saito, Kuniaki|Moriwaki, Hisataka|Hara, Akira
PMID: 20079348
Journal: J Immunol. 2010 Sep 15;185(6):3750-8.
Title: Netrin-1 regulates Th1/Th2/Th17 cytokine production and inflammation through UNC5B receptor and protects kidney against ischemia-reperfusion injury.
Author: Tadagavadi, Raghu Kempegowda|Wang, Weiwei|Ramesh, Ganesan
PMID: 20693423
Journal: Oncogene. 2010 Jun 10;29(23):3313-23.
Title: Inflammatory bowel disease and intestinal cancer: a paradigm of the Yin-Yang interplay between inflammation and cancer.
Author: Danese, S|Mantovani, A
PMID: 20400974
Journal: Inflamm Bowel Dis. 2010 Sep;16(9):1496-504.
Title: CCL2 (pM levels) as a therapeutic agent in Inflammatory Bowel Disease models in mice.
Author: Maharshak, N|Hart, G|Ron, E|Zelman, E|Sagiv, A|Arber, N|Brazowski, E|Margalit, R|Elinav, E|Shachar, I
PMID: 20222126
Journal: Inflamm Bowel Dis. 2010 Sep;16(9):1496-504.
Title: CCL2 (pM levels) as a therapeutic agent in Inflammatory Bowel Disease models in mice.
Author: Maharshak, N|Hart, G|Ron, E|Zelman, E|Sagiv, A|Arber, N|Brazowski, E|Margalit, R|Elinav, E|Shachar, I
PMID: 20222120
Journal: Exp Mol Med. 2010 Feb 28;42(2):143-54.
Title: Grifola frondosa water extract alleviates intestinal inflammation by suppressing TNF-alpha production and its signaling.
Author: Lee, Jong Suk|Park, Su Young|Thapa, Dinesh|Choi, Mi Kyoung|Chung, Ill Min|Park, Young Joon|Yong, Chul Soon|Choi, Han Gon|Kim, Jung Ae
PMID: 20054232
Journal: J Immunol. 2010 Feb 1;184(3):1630-41.
Title: Tumor microenvironments direct the recruitment and expansion of human Th17 cells.
Author: Su, Xinming|Ye, Jian|Hsueh, Eddy C|Zhang, Yanping|Hoft, Daniel F|Peng, Guangyong
PMID: 20026736
Journal: J Interferon Cytokine Res. 2011 Feb;31(2):219-26.
Title: Curcumin's effect on intestinal inflammation and tumorigenesis in the ApcMin/+ mouse.
Author: Murphy, E Angela|Davis, J Mark|McClellan, Jamie L|Gordon, Benjamin T|Carmichael, Martin D
PMID: 20950131
Journal: J Transl Med. 2011 Mar 30;9:33.
Title: In vitro migration of cytotoxic T lymphocyte derived from a colon carcinoma patient is dependent on CCL2 and CCR2.
Author: Berencsi, Klara|Rani, Pyapalli|Zhang, Tianqian|Gross, Laura|Mastrangelo, Michael|Meropol, Neal J|Herlyn, Dorothee|Somasundaram, Rajasekharan
PMID: 21450101
Journal: Cancer Microenviron. 2011 Aug;4(2):181-5.
Title: The colorectal tumor microenvironment: the next decade.
Author: Beauchemin, Nicole
PMID: 21735168
Journal: Cancer Microenviron. 2011 Aug;4(2):141-54.
Title: Tumor-associated Macrophages (TAM) and Inflammation in Colorectal Cancer.
Author: Erreni, Marco|Mantovani, Alberto|Allavena, Paola
PMID: 21909876
Journal: PLoS One. 2011;6(11):e27944.
Title: Tumour tissue microenvironment can inhibit dendritic cell maturation in colorectal cancer.
Author: Michielsen, Adriana J|Hogan, Andrew E|Marry, Joseph|Tosetto, Miriam|Cox, Fionnuala|Hyland, John M|Sheahan, Kieran D|O'Donoghue, Diarmuid P|Mulcahy, Hugh E|Ryan, Elizabeth J|O'Sullivan, Jacintha N
PMID: 22125641
Journal: Chirurgia (Bucur). 2012 Jan-Feb;107(1):59-65.
Title: [Perioperative immunologic changes in colorectal cancer patients].
Author: Neagu, S|Lerescu, L|Costea, R|Tucureanu, C|Caras, I|Gangura, G|Pitica, R|Salageanu, A
PMID: 22480118
Journal: Cancer Cell. 2012 Jul 10;22(1):91-105.
Title: Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathway.
Author: Wolf, Monika Julia|Hoos, Alexandra|Bauer, Judith|Boettcher, Steffen|Knust, Markus|Weber, Achim|Simonavicius, Nicole|Schneider, Christoph|Lang, Matthias|Sturzl, Michael|Croner, Roland S|Konrad, Andreas|Manz, Markus G|Moch, Holger|Aguzzi, Adriano|van Loo, G
PMID: 22789541
Journal: PLoS One. 2012;7(9):e45332.
Title: Hedgehog pathway signaling regulates human colon carcinoma HT-29 epithelial cell line apoptosis and cytokine secretion.
Author: Yoshimoto, Agnes N|Bernardazzi, Claudio|Carneiro, Antonio Jose V|Elia, Celeste C S|Martinusso, Cesonia A|Ventura, Grasiella M|Castelo-Branco, Morgana T L|de Souza, Heitor S P
PMID: 23028941
Journal: Scand J Clin Lab Invest. 2012 Dec;72(8):593-601.
Title: Human monocyte responses to lipopolysaccharide and 9-cis retinoic acid after laparoscopic surgery for colon cancer.
Author: Kolseth, Ingrid B M|Forland, Dag T|Risoe, Petter K|Flood-Kjeldsen, Signe|Agren, Joanna|Reseland, Janne E|Lyngstadaas, Staale P|Johnson, Egil|Dahle, Maria K
PMID: 23094762
Journal: Int J Mol Epidemiol Genet. 2012;3(4):294-304. Epub 2012 Nov 15.
Title: Plasma soluble receptor for advanced glycation end-products and risk of colorectal adenoma.
Author: Jiao, Li|Chen, Liang|Alsarraj, Abeer|Ramsey, David|Duan, Zhigang|El-Serag, Hashem B
PMID: 23205181
Journal: Cancer Lett. 2013 Aug 28;337(1):107-14.
Title: Profiles of circulating inflammatory cytokines in colorectal cancer (CRC), high cancer risk conditions, and health are distinct. Possible implications for CRC screening and surveillance.
Author: Krzystek-Korpacka, Malgorzata|Diakowska, Dorota|Kapturkiewicz, Bartosz|Bebenek, Marek|Gamian, Andrzej
PMID: 23726839
Journal: Cytokine. 2013 Oct;64(1):158-64.
Title: Circulating midkine in malignant and non-malignant colorectal diseases.
Author: Krzystek-Korpacka, Malgorzata|Diakowska, Dorota|Neubauer, Katarzyna|Gamian, Andrzej
PMID: 23899719
Journal: Cancer Res. 2013 Oct 1;73(19):5926-35.
Title: FGFR4 promotes stroma-induced epithelial-to-mesenchymal transition in colorectal cancer.
Author: Liu, Rui|Li, Jingyi|Xie, Ke|Zhang, Tao|Lei, Yunlong|Chen, Yi|Zhang, Lu|Huang, Kai|Wang, Kui|Wu, Hong|Wu, Min|Nice, Edouard C|Huang, Canhua|Wei, Yuquan
PMID: 23943801
Journal: Clin Cancer Res. 2013 Nov 1;19(21):6006-19.
Title: Proteome profiling of cancer-associated fibroblasts identifies novel proinflammatory signatures and prognostic markers for colorectal cancer.
Author: Torres, Sofia|Bartolome, Ruben A|Mendes, Marta|Barderas, Rodrigo|Fernandez-Acenero, M Jesus|Pelaez-Garcia, Alberto|Pena, Cristina|Lopez-Lucendo, Maria|Villar-Vazquez, Roi|de Herreros, Antonio Garcia|Bonilla, Felix|Casal, J Ignacio
PMID: 24025712
Journal: Enzymes. 2013;33 Pt A:213-48.
Title: A two-hybrid approach to identify inhibitors of the RAS-RAF interaction.
Author: Khazak, Vladimir|Eyrisch, Susanne|Kato, Juran|Tamanoi, Fuyuhiko|Golemis, Erica A
PMID: 25033807
Journal: Wiad Lek. 2013;66(1):3-9.
Title: [The role of TLR4 receptor in development of inflammation and carcinogenesis in ulcerative colitis and pharmacotherapy of this disorder].
Author: Szumilas, Dawid|Krysiak, Robert|Okopien, Boguslaw
PMID: 23905422
Journal: Biochimie. 2013 Mar;95(3):632-40.
Title: Evidence of cell damage induced by major components of a diet-compatible mixture of oxysterols in human colon cancer CaCo-2 cell line.
Author: Biasi, Fiorella|Chiarpotto, Elena|Sottero, Barbara|Maina, Marco|Mascia, Cinzia|Guina, Tina|Gamba, Paola|Gargiulo, Simona|Testa, Gabriella|Leonarduzzi, Gabriella|Poli, Giuseppe
PMID: 23092829
Journal: Cancer Med. 2013 Apr;2(2):234-42.
Title: Correlation of angiogenic biomarker signatures with clinical outcomes in metastatic colorectal cancer patients receiving capecitabine, oxaliplatin, and bevacizumab.
Author: Liu, Yingmiao|Starr, Mark D|Bulusu, Anuradha|Pang, Herbert|Wong, Nan Soon|Honeycutt, Wanda|Amara, Anthony|Hurwitz, Herbert I|Nixon, Andrew B
PMID: 23634291
Journal: Oncogene. 2013 Feb 14;32(7):849-60.
Title: Host-related carcinoembryonic antigen cell adhesion molecule 1 promotes metastasis of colorectal cancer.
Author: Arabzadeh, A|Chan, C|Nouvion, A-L|Breton, V|Benlolo, S|DeMarte, L|Turbide, C|Brodt, P|Ferri, L|Beauchemin, N
PMID: 22469976
Journal: Int Immunol. 2013 Jan;25(1):35-44.
Title: Interplay between T(h)1 and T(h)17 effector T-cell pathways in the pathogenesis of spontaneous colitis and colon cancer in the Galphai2-deficient mouse.
Author: Gotlind, Yu-Yuan|Fritsch Fredin, Maria|Kumawat, Ashok Kumar|Strid, Hilja|Willen, Roger|Rangel, Ignacio|Bland, Paul W|Hornquist, Elisabeth Hultgren
PMID: 22962436
Journal: Hepatology. 2013 Feb;57(2):829-39.
Title: Recruitment of a myeloid cell subset (CD11b/Gr1 mid) via CCL2/CCR2 promotes the development of colorectal cancer liver metastasis.
Author: Zhao, Lei|Lim, Su Yin|Gordon-Weeks, Alex N|Tapmeier, Thomas T|Im, Jae Hong|Cao, Yunhong|Beech, John|Allen, Danny|Smart, Sean|Muschel, Ruth J
PMID: 23081697
Journal: Cell Signal. 2013 Jan;25(1):178-89.
Title: Cripto-1 enhances the canonical Wnt/beta-catenin signaling pathway by binding to LRP5 and LRP6 co-receptors.
Author: Nagaoka, Tadahiro|Karasawa, Hideaki|Turbyville, Thomas|Rangel, Maria-Cristina|Castro, Nadia P|Gonzales, Monica|Baker, Alyson|Seno, Masaharu|Lockett, Stephen|Greer, Yoshimi E|Rubin, Jeffrey S|Salomon, David S|Bianco, Caterina
PMID: 23022962
Journal: Am J Physiol Gastrointest Liver Physiol. 2014 Jan 1;306(1):G27-36.
Title: Paeoniflorin abrogates DSS-induced colitis via a TLR4-dependent pathway.
Author: Zhang, Jingjing|Dou, Wei|Zhang, Eryun|Sun, Aning|Ding, Lili|Wei, Xiaohui|Chou, Guixin|Mani, Sridhar|Wang, Zhengtao
PMID: 24232001
Journal: BMC Complement Altern Med. 2014 Dec 15;14:490.
Title: The number of intestinal bacteria is not critical for the enhancement of antitumor activity and reduction of intestinal toxicity of irinotecan by the Chinese herbal medicine PHY906 (KD018).
Author: Lam, Wing|Jiang, Zaoli|Guan, Fulan|Hu, Rong|Liu, Shwu-Huey|Chu, Edward|Cheng, Yung-Chi
PMID: 25510341
Journal: Acta Histochem. 2015 Sep;117(7):635-41.
Title: Spatiotemporal expression of Rhomboid domain containing 2 (Rhbdd2) during rat development.
Author: Ferretti, V A|Canzoneri, R|Barbeito, C G|Croce, M V|Abba, M C|Lacunza, E
PMID: 26093883
Journal: Oncotarget. 2015 Nov 24;6(37):40327-36.
Title: Genome-wide association study identifies two new susceptibility loci for colorectal cancer at 5q23.3 and 17q12 in Han Chinese.
Author: Jiang, Kewei|Sun, Yimin|Wang, Cheng|Ji, Jiafu|Li, Yaoping|Ye, Yingjiang|Lv, Liang|Guo, Yong|Guo, Sutang|Li, Hai|Zhang, Lianhai|Zhou, Yanbing|Jiang, Bo|Ren, Yonghong|Xu, Youchun|Yang, Xiongfei|Liu, Hongxia|Wang, Yirui|Shen, Zhanlong|Qin, Wenyan|Guo, Peng|J
PMID: 26515597
Journal: Oncotarget. 2015 Oct 6;6(30):29725-39.
Title: CCL2 is transcriptionally controlled by the lysosomal protease cathepsin S in a CD74-dependent manner.
Author: Wilkinson, Richard D A|Magorrian, Sinead M|Williams, Rich|Young, Andrew|Small, Donna M|Scott, Christopher J|Burden, Roberta E
PMID: 26358505
Journal: Cell Rep. 2015 Jul 14;12(2):244-57.
Title: CCL2 Promotes Colorectal Carcinogenesis by Enhancing Polymorphonuclear Myeloid-Derived Suppressor Cell Population and Function.
Author: Chun, Eunyoung|Lavoie, Sydney|Michaud, Monia|Gallini, Carey Ann|Kim, Jason|Soucy, Genevieve|Odze, Robert|Glickman, Jonathan N|Garrett, Wendy S
PMID: 26146082
Journal: Biomed Res Int. 2015;2015:523930.
Title: Nampt/PBEF/visfatin upregulation in colorectal tumors, mirrored in normal tissue and whole blood of colorectal cancer patients, is associated with metastasis, hypoxia, IL1beta, and anemia.
Author: Neubauer, Katarzyna|Misa, Iwona Bednarz|Diakowska, Dorota|Kapturkiewicz, Bartosz|Gamian, Andrzej|Krzystek-Korpacka, Malgorzata
PMID: 26075243
Journal: Pol Arch Med Wewn. 2015;125(6):443-51. Epub 2015 May 28.
Title: Preoperative serum chemokine (C-C motif) ligand 2 levels and prognosis in colorectal cancer.
Author: Szczepanik, Antoni M|Siedlar, Maciej|Szura, Miroslaw|Kibil, Wojciech|Brzuszkiewicz, Karolina|Brandt, Philip|Kulig, Jan
PMID: 26020569
Journal: Cell Cycle. 2015;14(16):2667-76.
Title: Leptin activation of mTOR pathway in intestinal epithelial cell triggers lipid droplet formation, cytokine production and increased cell proliferation.
Author: Fazolini, Narayana P B|Cruz, Andre L S|Werneck, Miriam B F|Viola, Joao P B|Maya-Monteiro, Clarissa M|Bozza, Patricia T
PMID: 26017929
Journal: Cancer Biol Ther. 2015;16(5):671-7.
Title: Laparoscopic surgery for colorectal cancer is not associated with an increase in the circulating levels of several inflammation-related factors.
Author: Crucitti, Antonio|Corbi, Maddalena|Tomaiuolo, Pasquina Mc|Fanali, Caterina|Mazzari, Andrea|Lucchetti, Donatella|Migaldi, Mario|Sgambato, Alessandro
PMID: 25875151
Journal: Cancer Sci. 2015 Jun;106(6):692-9.
Title: Antitumor activity of the MEK inhibitor trametinib on intestinal polyp formation in Apc(Delta716) mice involves stromal COX-2.
Author: Fujishita, Teruaki|Kajino-Sakamoto, Rie|Kojima, Yasushi|Taketo, Makoto Mark|Aoki, Masahiro
PMID: 25855137
Journal: Cell. 2015 Feb 12;160(4):700-714.
Title: PTX3 is an extrinsic oncosuppressor regulating complement-dependent inflammation in cancer.
Author: Bonavita, Eduardo|Gentile, Stefania|Rubino, Marcello|Maina, Virginia|Papait, Roberto|Kunderfranco, Paolo|Greco, Carolina|Feruglio, Francesca|Molgora, Martina|Laface, Ilaria|Tartari, Silvia|Doni, Andrea|Pasqualini, Fabio|Barbati, Elisa|Basso, Gianluca|Gald
PMID: 25679762
Journal: Sci Rep. 2016 Oct 14;6:34523.
Title: Preclinical validation of the small molecule drug quininib as a novel therapeutic for colorectal cancer.
Author: Murphy, Adrian G|Casey, Rory|Maguire, Aoife|Tosetto, Miriam|Butler, Clare T|Conroy, Emer|Reynolds, Alison L|Sheahan, Kieran|O'Donoghue, Diarmuid|Gallagher, William M|Fennelly, David|Kennedy, Breandan N|O'Sullivan, Jacintha
PMID: 27739445
Journal: Oncoimmunology. 2016 May 24;5(8):e1189052.
Title: Stromal CCR6 drives tumor growth in a murine transplantable colon cancer through recruitment of tumor-promoting macrophages.
Author: Nandi, Bisweswar|Shapiro, Mia|Samur, Mehmet K|Pai, Christine|Frank, Natasha Y|Yoon, Charles|Prabhala, Rao H|Munshi, Nikhil C|Gold, Jason S
PMID: 27622061
Journal: PLoS One. 2016 Aug 11;11(8):e0160891.
Title: Intricate Macrophage-Colorectal Cancer Cell Communication in Response to Radiation.
Author: Pinto, Ana T|Pinto, Marta L|Velho, Sergia|Pinto, Marta T|Cardoso, Ana P|Figueira, Rita|Monteiro, Armanda|Marques, Margarida|Seruca, Raquel|Barbosa, Mario A|Mareel, Marc|Oliveira, Maria J|Rocha, Sonia
PMID: 27513864
Journal: J Cancer Res Clin Oncol. 2016 Aug;142(8):1775-80.
Title: Prognostic relevance of genetic variants involved in immune checkpoints in patients with colorectal cancer.
Author: Yoon, Shinkyo|Kang, Byung Woog|Park, Su Yeon|Kim, Hye Jin|Park, Jun Seok|Choi, Gyu Seog|Kim, Jong Gwang
PMID: 27339628
Journal: Oncotarget. 2016 May 10;7(19):28139-50.
Title: Changes in plasma chemokine C-C motif ligand 2 levels during treatment with eicosapentaenoic acid predict outcome in patients undergoing surgery for colorectal cancer liver metastasis.
Author: Volpato, Milene|Perry, Sarah L|Marston, Gemma|Ingram, Nicola|Cockbain, Andrew J|Burghel, Heather|Mann, Jake|Lowes, David|Wilson, Erica|Droop, Alastair|Randerson-Moor, Juliette|Coletta, P Louise|Hull, Mark A
PMID: 27058904
Journal: PLoS One. 2016 Feb 9;11(2):e0148186.
Title: Circulating Inflammatory Mediators as Potential Prognostic Markers of Human Colorectal Cancer.
Author: Di Caro, Giuseppe|Carvello, Michele|Pesce, Samantha|Erreni, Marco|Marchesi, Federica|Todoric, Jelena|Sacchi, Matteo|Montorsi, Marco|Allavena, Paola|Spinelli, Antonino
PMID: 26859579
Journal: Tumour Biol. 2016 Jul;37(7):9077-88.
Title: Cadherin-12 enhances proliferation in colorectal cancer cells and increases progression by promoting EMT.
Author: Ma, Junjun|Zhao, Jingkun|Lu, Jun|Wang, Puxiongzhi|Feng, Hao|Zong, Yaping|Ou, Baochi|Zheng, Minhua|Lu, Aiguo
PMID: 26762412
Journal: Biochem Biophys Res Commun. 2016 Jan 22;469(4):878-83.
Title: Heparanase augments inflammatory chemokine production from colorectal carcinoma cell lines.
Author: Tsunekawa, Naoki|Higashi, Nobuaki|Kogane, Yusuke|Waki, Michihiko|Shida, Hiroaki|Nishimura, Yoshio|Adachi, Hayamitsu|Nakajima, Motowo|Irimura, Tatsuro
PMID: 26713365
Journal: Br J Cancer. 2016 Jan 12;114(1):37-43.
Title: An antitumorigenic role for the IL-33 receptor, ST2L, in colon cancer.
Author: O'Donnell, Charlotte|Mahmoud, Amr|Keane, Jonathan|Murphy, Carola|White, Declan|Carey, Sinead|O'Riordain, Micheal|Bennett, Michael W|Brint, Elizabeth|Houston, Aileen
PMID: 26679377
Journal: Oncogene. 2016 May 19;35(20):2634-44.
Title: Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling.
Author: Sanchez-Lopez, E|Flashner-Abramson, E|Shalapour, S|Zhong, Z|Taniguchi, K|Levitzki, A|Karin, M
PMID: 26364612
Journal: Gut. 2016 May;65(5):821-9.
Title: Carcinoembryonic Antigen Cell Adhesion Molecule 1 long isoform modulates malignancy of poorly differentiated colon cancer cells.
Author: Arabzadeh, Azadeh|Dupaul-Chicoine, Jeremy|Breton, Valerie|Haftchenary, Sina|Yumeen, Sara|Turbide, Claire|Saleh, Maya|McGregor, Kevin|Greenwood, Celia M T|Akavia, Uri David|Blumberg, Richard S|Gunning, Patrick T|Beauchemin, Nicole
PMID: 25666195
Journal: Br J Cancer. 2016 Mar 15;114(6):697-703.
Title: Ectopic expression of the chemokine CXCL17 in colon cancer cells.
Author: Ohlsson, Lina|Hammarstrom, Marie-Louise|Lindmark, Gudrun|Hammarstrom, Sten|Sitohy, Basel
PMID: 26889977
Journal: J Ethnopharmacol. 2017 Sep 14;209:305-316.
Title: Danshen improves survival of patients with colon cancer and dihydroisotanshinone I inhibit the proliferation of colon cancer cells via apoptosis and skp2 signaling pathway.
Author: Lin, Yin-Yin|Lee, I-Yun|Huang, Wen-Shih|Lin, Yu-Shin|Kuan, Feng-Che|Shu, Li-Hsin|Cheng, Yu-Ching|Yang, Yao-Hsu|Wu, Ching-Yuan
PMID: 28807849
Journal: Oncotarget. 2017 Nov 1;8(61):104330-104346.
Title: EphA2 signaling is impacted by carcinoembryonic antigen cell adhesion molecule 1-L expression in colorectal cancer liver metastasis in a cell context-dependent manner.
Author: Arabzadeh, Azadeh|McGregor, Kevin|Breton, Valerie|Van Der Kraak, Lauren|Akavia, Uri David|Greenwood, Celia M T|Beauchemin, Nicole
PMID: 29262644
Journal: Pol Przegl Chir. 2017 Oct 31;89(5):1-5.
Title: An association of the MCP-1 and CCR2 single nucleotide polymorphisms with colorectal cancer prevalence.
Author: Walczak, Anna|Przybylowska-Sygut, Karolina|Sygut, Andrzej|Cieslak, Adrianna|Mik, Michal|Dziki, Lukasz|Dziki, Adam|Majsterek, Ireneusz
PMID: 29154245
Journal: Sci Rep. 2017 Sep 19;7(1):11864.
Title: Oligo-Fucoidan prevents IL-6 and CCL2 production and cooperates with p53 to suppress ATM signaling and tumor progression.
Author: Chen, Li-Mei|Liu, Po-Yen|Chen, Yen-An|Tseng, Hong-Yu|Shen, Pei-Chun|Hwang, Pai-An|Hsu, Hsin-Ling
PMID: 28928376
Journal: Oncoimmunology. 2017 May 16;6(7):e1328338.
Title: IL-32alpha-induced inflammation constitutes a link between obesity and colon cancer.
Author: Catalan, Victoria|Gomez-Ambrosi, Javier|Rodriguez, Amaia|Ramirez, Beatriz|Ortega, Victor A|Hernandez-Lizoain, Jose Luis|Baixauli, Jorge|Becerril, Sara|Rotellar, Fernando|Valenti, Victor|Moncada, Rafael|Silva, Camilo|Salvador, Javier|Fruhbeck, Gema
PMID: 28811968
Journal: Sci Rep. 2017 Jul 14;7(1):5374.
Title: Decreased serum apolipoprotein A1 levels are associated with poor survival and systemic inflammatory response in colorectal cancer.
Author: Sirnio, Paivi|Vayrynen, Juha P|Klintrup, Kai|Makela, Jyrki|Makinen, Markus J|Karttunen, Tuomo J|Tuomisto, Anne
PMID: 28710487
Journal: Sci Rep. 2017 Jul 11;7(1):5107.
Title: The PSMP-CCR2 interactions trigger monocyte/macrophage-dependent colitis.
Author: Pei, Xiaolei|Zheng, Danfeng|She, Shaoping|Ma, Jing|Guo, Changyuan|Mo, Xiaoning|Zhang, Yingmei|Song, Quansheng|Zhang, Yu|Ma, Dalong|Wang, Ying
PMID: 28698550
Journal: Oncoimmunology. 2017 Jan 19;6(3):e1282589.
Title: Oral delivery of tumor microparticle vaccines activates NOD2 signaling pathway in ileac epithelium rendering potent antitumor T cell immunity.
Author: Dong, Wenqian|Zhang, Huafeng|Yin, Xiaonan|Liu, Yuying|Chen, Degao|Liang, Xiaoyu|Jin, Xun|Lv, Jiadi|Ma, Jingwei|Tang, Ke|Hu, Zhuowei|Qin, Xiaofeng|Huang, Bo
PMID: 28405506
Journal: Tumour Biol. 2017 Mar;39(3):1010428317695962.
Title: Specific tumor-derived CCL2 mediated by pyruvate kinase M2 in colorectal cancer cells contributes to macrophage recruitment in tumor microenvironment.
Author: Zou, Kejian|Wang, Yaodong|Hu, Yan|Zheng, Liansheng|Xu, Wanfu|Li, Guoxin
PMID: 28347237
Journal: Biochem Biophys Res Commun. 2017 May 20;487(1):8-14.
Title: FAP positive fibroblasts induce immune checkpoint blockade resistance in colorectal cancer via promoting immunosuppression.
Author: Chen, Lingling|Qiu, Xiangting|Wang, Xinhua|He, Jian
PMID: 28302482
Journal: Cytokine. 2018 Oct;110:435-441.
Title: Subsite heterogeneity in the profiles of circulating cytokines in colorectal cancer.
Author: Krzystek-Korpacka, Malgorzata|Zawadzki, Marek|Kapturkiewicz, Bartosz|Lewandowska, Paulina|Bednarz-Misa, Iwona|Gorska, Sabina|Witkiewicz, Wojciech|Gamian, Andrzej
PMID: 29801973
Journal: PLoS One. 2018 Jun 7;13(6):e0198099.
Title: Interrogation of transcriptomic changes associated with drug-induced hepatic sinusoidal dilatation in colorectal cancer.
Author: Jarzabek, Monika A|Proctor, William R|Vogt, Jennifer|Desai, Rupal|Dicker, Patrick|Cain, Gary|Raja, Rajiv|Brodbeck, Jens|Stevens, Dale|van der Stok, Eric P|Martens, John W M|Verhoef, Cornelis|Hegde, Priti S|Byrne, Annette T|Tarrant, Jacqueline M
PMID: 29879147
Journal: Int J Cancer. 2018 Aug 21.
Title: Circulating Inflammatory Markers and Colorectal Cancer Risk: A Prospective Case-cohort Study in Japan.
Author: Song, Minkyo|Sasazuki, Shizuka|Camargo, M Constanza|Shimazu, Taichi|Charvat, Hadrien|Yamaji, Taiki|Sawada, Norie|Kemp, Troy J|Pfeiffer, Ruth M|Hildesheim, Allan|Pinto, Ligia A|Rabkin, Charles S|Tsugane, Shoichiro
PMID: 30132835
Journal: Oncoimmunology. 2018 Aug 1;7(9):e1470729.
Title: Recruitment of CCR2(+) tumor associated macrophage to sites of liver metastasis confers a poor prognosis in human colorectal cancer.
Author: Grossman, Julie G|Nywening, Timothy M|Belt, Brian A|Panni, Roheena Z|Krasnick, Bradley A|DeNardo, David G|Hawkins, William G|Goedegebuure, S Peter|Linehan, David C|Fields, Ryan C
PMID: 30228938
Journal: J Cachexia Sarcopenia Muscle. 2018 Oct 3.
Title: Peritumoural adipose tissue pro-inflammatory cytokines are associated with tumoural growth factors in cancer cachexia patients.
Author: Neto, Nelson Inacio Pinto|Murari, Ariene Soares de Pinho|Oyama, Lila Missae|Otoch, Jose Pinhata|Alcantara, Paulo Sergio Martins|Tokeshi, Flavio|Figueredo, Raquel Galvao|Alves, Michele Joana|Lima, Joanna Darck Carola Correia|Matos-Neto, Emidio Marques de|S
PMID: 30284380
Journal: Front Immunol. 2018 Sep 21;9:1857.
Title: MK2 Regulates Macrophage Chemokine Activity and Recruitment to Promote Colon Tumor Growth.
Author: Phinney, Brandon B|Ray, Anita L|Peretti, Amanda S|Jerman, Stephanie J|Grim, Carl|Pinchuk, Irina V|Beswick, Ellen J
PMID: 30298062