Primary Site >> Colorectal Cancer

Gene >> CASP9

Journal: Clin Cancer Res. 2000 May;6(5):2021-7.
Title: Photodynamic therapy with the phthalocyanine photosensitizer Pc 4 of SW480 human colon cancer xenografts in athymic mice.
Author: Whitacre, C M|Feyes, D K|Satoh, T|Grossmann, J|Mulvihill, J W|Mukhtar, H|Oleinick, N L
PMID: 10815928
Journal: Cancer Res. 2000 Nov 15;60(22):6259-65.
Title: The caspase 9 inhibitor Z-LEHD-FMK protects human liver cells while permitting death of cancer cells exposed to tumor necrosis factor-related apoptosis-inducing ligand.
Author: Ozoren, N|Kim, K|Burns, T F|Dicker, D T|Moscioni, A D|El-Deiry, W S
PMID: 11103780
Journal: Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3416-21.
Title: The dependence receptor DCC (deleted in colorectal cancer) defines an alternative mechanism for caspase activation.
Author: Forcet, C|Ye, X|Granger, L|Corset, V|Shin, H|Bredesen, D E|Mehlen, P
PMID: 11248093
Journal: Hum Pathol. 2001 May;32(5):461-7.
Title: Caspase 7 downregulation as an immunohistochemical marker of colonic carcinoma.
Author: Palmerini, F|Devilard, E|Jarry, A|Birg, F|Xerri, L
PMID: 11381362
Journal: J Biol Chem. 2001 Aug 24;276(34):32220-9. Epub 2001 Jun 14.
Title: TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer.
Author: Pathan, N|Marusawa, H|Krajewska, M|Matsuzawa, S|Kim, H|Okada, K|Torii, S|Kitada, S|Krajewski, S|Welsh, K|Pio, F|Godzik, A|Reed, J C
PMID: 11408476
Journal: Oncogene. 2001 Jun 21;20(28):3726-34.
Title: The monoclonal antibody 225 activates caspase-8 and induces apoptosis through a tumor necrosis factor receptor family-independent pathway.
Author: Liu, B|Fan, Z
PMID: 11439335
Journal: Int J Cancer. 2001 Aug 15;93(4):526-33.
Title: Induction of apoptosis in human colon carcinoma cells HT29 by sublethal cryo-injury: mediation by cytochrome c release.
Author: Hanai, A|Yang, W L|Ravikumar, T S
PMID: 11477556
Journal: J Biol Chem. 2001 Oct 19;276(42):38748-54. Epub 2001 Aug 20.
Title: A Fas-associated death domain protein-dependent mechanism mediates the apoptotic action of non-steroidal anti-inflammatory drugs in the human leukemic Jurkat cell line.
Author: Han, Z|Pantazis, P|Wyche, J H|Kouttab, N|Kidd, V J|Hendrickson, E A
PMID: 11514566
Journal: Mol Carcinog. 2001 Oct;32(2):73-83.
Title: Molecular mechanisms of apoptosis induced by magnolol in colon and liver cancer cells.
Author: Lin, S Y|Chang, Y T|Liu, J D|Yu, C H|Ho, Y S|Lee, Y H|Lee, W S
PMID: 11746819
Journal: Cancer Res. 2002 Mar 15;62(6):1583-7.
Title: Requirement of BAX for TRAIL/Apo2L-induced apoptosis of colorectal cancers: synergism with sulindac-mediated inhibition of Bcl-x(L).
Author: Ravi, Rajani|Bedi, Atul
PMID: 11912124
Journal: Exp Cell Res. 2002 Jun 10;276(2):214-22.
Title: The p53 stabilizing compound CP-31398 induces apoptosis by activating the intrinsic Bax/mitochondrial/caspase-9 pathway.
Author: Luu, Yvonne|Bush, Jason|Cheung, K-John Jr|Li, Gang
PMID: 12027451
Journal: Clin Cancer Res. 2002 Jun;8(6):1940-7.
Title: Augmentation of sodium butyrate-induced apoptosis by phosphatidylinositol 3'-kinase inhibition in the KM20 human colon cancer cell line.
Author: Wang, Qingding|Li, Nan|Wang, Xiaofu|Kim, Myung M|Evers, B Mark
PMID: 12060639
Journal: Neoplasia. 2002 Nov-Dec;4(6):551-7.
Title: Defining characteristics of Types I and II apoptotic cells in response to TRAIL.
Author: Ozoren, Nesrin|El-Deiry, Wafik S
PMID: 12407450
Journal: Exp Cell Res. 2002 Dec 10;281(2):175-81.
Title: Heat shock protects HCT116 and H460 cells from TRAIL-induced apoptosis.
Author: Ozoren, Nesrin|El-Deiry, Wafik
PMID: 12460647
Journal: Carcinogenesis. 2002 Dec;23(12):2087-93.
Title: Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells.
Author: Liu, Jian-Jun|Nilsson, Ake|Oredsson, Stina|Badmaev, Vladimir|Zhao, Wan-Zhou|Duan, Rui-Dong
PMID: 12507932
Journal: Gut. 2003 Jan;52(1):94-100.
Title: Butyrate induced Caco-2 cell apoptosis is mediated via the mitochondrial pathway.
Author: Ruemmele, F M|Schwartz, S|Seidman, E G|Dionne, S|Levy, E|Lentze, M J
PMID: 12477768
Journal: FEBS Lett. 2003 Mar 13;538(1-3):19-24.
Title: Human colon cancer cells differ in their sensitivity to curcumin-induced apoptosis and heat shock protects them by inhibiting the release of apoptosis-inducing factor and caspases.
Author: Rashmi, R|Santhosh Kumar, T R|Karunagaran, D
PMID: 12633846
Journal: Oncogene. 2003 May 1;22(17):2674-9.
Title: Effect of Bax deficiency on death receptor 5 and mitochondrial pathways during endoplasmic reticulum calcium pool depletion-induced apoptosis.
Author: He, Qin|Montalbano, JoAnne|Corcoran, Chad|Jin, Weixin|Huang, Ying|Sheikh, M Saeed
PMID: 12730681
Journal: Am J Physiol Gastrointest Liver Physiol. 2003 Dec;285(6):G1097-110.
Title: Precursor peptide progastrin(1-80) reduces apoptosis of intestinal epithelial cells and upregulates cytochrome c oxidase Vb levels and synthesis of ATP.
Author: Wu, Hai|Owlia, Azarmidokht|Singh, Pomila
PMID: 12881229
Journal: J Cell Biochem. 2003 Aug 15;89(6):1102-14.
Title: Pro-apoptotic activity of transiently expressed BCL-2 occurs independent of BAX and BAK.
Author: Subramanian, T|Chinnadurai, G
PMID: 12898509
Journal: Oncogene. 2003 Aug 7;22(32):4953-63.
Title: The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells.
Author: Johnson, Thomas R|Stone, Kimberley|Nikrad, Malti|Yeh, Tammie|Zong, Wei-Xing|Thompson, Craig B|Nesterov, Alexandre|Kraft, Andrew S
PMID: 12902978
Journal: Cancer Res. 2003 Aug 1;63(15):4368-74.
Title: Regulation of caspase expression and apoptosis by adenomatous polyposis coli.
Author: Chen, Tingan|Yang, Ivana|Irby, Rosalyn|Shain, Kenneth H|Wang, Hong Gang|Quackenbush, John|Coppola, Domenico|Cheng, Jin Q|Yeatman, Timothy J
PMID: 12907606
Journal: Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):15095-100. Epub 2003 Nov 26.
Title: Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy.
Author: Wang, Shulin|El-Deiry, Wafik S
PMID: 14645705
Journal: Cell Cycle. 2004 Feb;3(2):205-11.
Title: Tocotrienol-rich fraction of palm oil activates p53, modulates Bax/Bcl2 ratio and induces apoptosis independent of cell cycle association.
Author: Agarwal, Mukesh K|Agarwal, Munna L|Athar, Mohammad|Gupta, Sanjay
PMID: 14712090
Journal: Ann Surg Oncol. 2004 Feb;11(2):192-6.
Title: Deleted in oral cancer-1 expression upregulates proapoptosis elements in microsatellite-unstable human colorectal cancer.
Author: Sotsky Kent, Tara|Yuan, Ziqiang|Miller, Agnes|Weber, Thomas K
PMID: 14761923
Journal: Cancer Res. 2004 Feb 1;64(3):1110-3.
Title: Induction of apoptosis and down-regulation of Bcl-XL in cancer cells by a novel small molecule, 2[[3-(2,3-dichlorophenoxy)propyl]amino]ethanol.
Author: Wu, Shuhong|Zhu, Hongbo|Gu, Jian|Zhang, Lidong|Teraishi, Fuminori|Davis, John J|Jacob, Dietmar A|Fang, Bingliang
PMID: 14871845
Journal: Biochem Pharmacol. 2004 Apr 15;67(8):1469-78.
Title: Cyclooxygenase-2 (COX-2)-dependent and -independent anticarcinogenic effects of celecoxib in human colon carcinoma cells.
Author: Maier, Thorsten Jurgen|Schilling, Karin|Schmidt, Ronald|Geisslinger, Gerd|Grosch, Sabine
PMID: 15041464
Journal: Arch Biochem Biophys. 2004 Apr 15;424(2):119-27.
Title: Role of caspase activation in butyrate-induced terminal differentiation of HT29 colon carcinoma cells.
Author: Cai, Jiyang|Chen, Yan|Murphy, T J|Jones, Dean P|Sartorelli, Alan C
PMID: 15047183
Journal: J Biol Chem. 2004 Jun 11;279(24):25813-22. Epub 2004 Apr 8.
Title: Sulforaphane-induced G2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25C.
Author: Singh, Shivendra V|Herman-Antosiewicz, Anna|Singh, Ajita V|Lew, Karen L|Srivastava, Sanjay K|Kamath, Ravindra|Brown, Kevin D|Zhang, Lin|Baskaran, Rajasekaran
PMID: 15073169
Journal: Exp Mol Pathol. 2004 Jun;76(3):196-204.
Title: CD44 negatively regulates apoptosis in murine colonic epithelium via the mitochondrial pathway.
Author: Lakshman, Minalini|Subramaniam, Venkateswaran|Jothy, Serge
PMID: 15126101
Journal: J Biol Chem. 2004 Aug 27;279(35):36680-8.
Title: Oncogenic Ras promotes butyrate-induced apoptosis through inhibition of gelsolin expression.
Author: Klampfer, Lidija|Huang, Jie|Sasazuki, Takehiko|Shirasawa, Senji|Augenlicht, Leonard
PMID: 15213223
Journal: Exp Mol Pathol. 2004 Aug;77(1):18-25.
Title: CD44 promotes resistance to apoptosis in human colon cancer cells.
Author: Lakshman, Minalini|Subramaniam, Venkateswaran|Rubenthiran, Umayal|Jothy, Serge
PMID: 15215046
Journal: J Biol Chem. 2004 Sep 17;279(38):40044-52. Epub 2004 Jun 28.
Title: Death induction by recombinant native TRAIL and its prevention by a caspase 9 inhibitor in primary human esophageal epithelial cells.
Author: Kim, Seok-Hyun|Kim, Kunhong|Kwagh, Jae G|Dicker, David T|Herlyn, Meenhard|Rustgi, Anil K|Chen, Youhai|El-Deiry, Wafik S
PMID: 15226295
Journal: Int J Cancer. 2004 Nov 10;112(3):433-45.
Title: Unconjugated bilirubin induces apoptosis in colon cancer cells by triggering mitochondrial depolarization.
Author: Keshavan, Pavitra|Schwemberger, Sandy J|Smith, Darcey L H|Babcock, George F|Zucker, Stephen D
PMID: 15382069
Journal: J Exp Ther Oncol. 2004 Dec;4(4):267-79.
Title: Atiprimod is an inhibitor of cancer cell proliferation and angiogenesis.
Author: Shailubhai, Kunwar|Dheer, Surendra|Picker, Donald|Kaur, Gurmeet|Sausville, Edward A|Jacob, Gary S
PMID: 15844657
Journal: J Biol Chem. 2005 Feb 4;280(5):3295-304.
Title: Combination of 5-fluorouracil and N1,N11-diethylnorspermine markedly activates spermidine/spermine N1-acetyltransferase expression, depletes polyamines, and synergistically induces apoptosis in colon carcinoma cells.
Author: Choi, Woonyoung|Gerner, Eugene W|Ramdas, Latha|Dupart, Jheri|Carew, Jennifer|Proctor, Lynsey|Huang, Peng|Zhang, Wei|Hamilton, Stanley R
PMID: 15546879
Journal: Cell Death Differ. 2005 Feb;12(2):128-35.
Title: Different apoptotic mechanisms are involved in the antiproliferative effects of 7beta-hydroxysitosterol and 7beta-hydroxycholesterol in human colon cancer cells.
Author: Roussi, S|Winter, A|Gosse, F|Werner, D|Zhang, X|Marchioni, E|Geoffroy, P|Miesch, M|Raul, F
PMID: 15550935
Journal: J Transl Med. 2005 Feb 3;3(1):7.
Title: In vitro and in vivo evaluation of NCX 4040 cytotoxic activity in human colon cancer cell lines.
Author: Tesei, Anna|Ulivi, Paola|Fabbri, Francesco|Rosetti, Marco|Leonetti, Carlo|Scarsella, Marco|Zupi, Gabriella|Amadori, Dino|Bolla, Manlio|Zoli, Wainer
PMID: 15691389
Journal: Br J Cancer. 2005 Apr 25;92(8):1430-41.
Title: HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo.
Author: Pukac, L|Kanakaraj, P|Humphreys, R|Alderson, R|Bloom, M|Sung, C|Riccobene, T|Johnson, R|Fiscella, M|Mahoney, A|Carrell, J|Boyd, E|Yao, X T|Zhang, L|Zhong, L|von Kerczek, A|Shepard, L|Vaughan, T|Edwards, B|Dobson, C|Salcedo, T|Albert, V
PMID: 15846298
Journal: Carcinogenesis. 2005 Oct;26(10):1716-30. Epub 2005 May 19.
Title: Justicidin A decreases the level of cytosolic Ku70 leading to apoptosis in human colorectal cancer cells.
Author: Lee, Jenq-Chang|Lee, Chao-Hung|Su, Chun-Li|Huang, Chung-Wei|Liu, Hsiao-Sheng|Lin, Chun-Nan|Won, Shen-Jeu
PMID: 15905197
Journal: Cancer Res. 2005 Aug 15;65(16):7436-45.
Title: Reactive oxygen species regulate caspase activation in tumor necrosis factor-related apoptosis-inducing ligand-resistant human colon carcinoma cell lines.
Author: Izeradjene, Kamel|Douglas, Leslie|Tillman, David M|Delaney, Addison B|Houghton, Janet A
PMID: 16103097
Journal: Cancer Res. 2005 Oct 1;65(19):8706-14.
Title: A novel isoform of TUCAN is overexpressed in human cancer tissues and suppresses both caspase-8- and caspase-9-mediated apoptosis.
Author: Yamamoto, Masaaki|Torigoe, Toshihiko|Kamiguchi, Kenjiro|Hirohashi, Yoshihiko|Nakanishi, Katsuya|Nabeta, Chika|Asanuma, Hiroko|Tsuruma, Tetsuhiro|Sato, Takashi|Hata, Fumitake|Ohmura, Tousei|Yamaguchi, Koji|Kurotaki, Takehiro|Hirata, Koichi|Sato, Noriyuki
PMID: 16204039
Journal: Mol Cancer Ther. 2005 Oct;4(10):1475-83.
Title: Sulindac sulfide-induced apoptosis is enhanced by a small-molecule Bcl-2 inhibitor and by TRAIL in human colon cancer cells overexpressing Bcl-2.
Author: Sinicrope, Frank A|Penington, Robert C
PMID: 16227396
Journal: Cancer Biol Ther. 2005 Oct;4(10):1159-67. Epub 2005 Oct 23.
Title: Chemotherapy regimen GOLF induces apoptosis in colon cancer cells through multi-chaperone complex inactivation and increased Raf-1 ubiquitin-dependent degradation.
Author: Caraglia, Michele|Marra, Monica|Budillon, Alfredo|Meo, Giuseppina|Ricciardiello, Filippo|Bismuto, Ettore|Brachelente, Giovanni|Francini, Guido|Giordano, Antonio|Correale, Pierpaolo|Abbruzzese, Alberto
PMID: 16294035
Journal: Gut. 2006 Feb;55(2):234-42. Epub 2005 Aug 23.
Title: Increased expression of high mobility group box 1 (HMGB1) is associated with an elevated level of the antiapoptotic c-IAP2 protein in human colon carcinomas.
Author: Volp, K|Brezniceanu, M-L|Bosser, S|Brabletz, T|Kirchner, T|Gottel, D|Joos, S|Zornig, M
PMID: 16118352
Journal: BMC Cancer. 2006 Jan 17;6:13.
Title: Comparative effects of RRR-alpha- and RRR-gamma-tocopherol on proliferation and apoptosis in human colon cancer cell lines.
Author: Campbell, Sharon E|Stone, William L|Lee, Steven|Whaley, Sarah|Yang, Hongsong|Qui, Min|Goforth, Paige|Sherman, Devin|McHaffie, Derek|Krishnan, Koyamangalath
PMID: 16417629
Journal: J Nutr Biochem. 2006 Sep;17(9):611-25.
Title: The dietary hydrolysable tannin punicalagin releases ellagic acid that induces apoptosis in human colon adenocarcinoma Caco-2 cells by using the mitochondrial pathway.
Author: Larrosa, Mar|Tomas-Barberan, Francisco A|Espin, Juan Carlos
PMID: 16426830
Journal: Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4128-33. Epub 2006 Mar 6.
Title: The dependence receptor DCC requires lipid raft localization for cell death signaling.
Author: Furne, Celine|Corset, Veronique|Herincs, Zoltan|Cahuzac, Nathalie|Hueber, Anne-Odile|Mehlen, Patrick
PMID: 16537496
Journal: J Environ Pathol Toxicol Oncol. 2006;25(1-2):159-71.
Title: Induction of apoptosis by hexaminolevulinate-mediated photodynamic therapy in human colon carcinoma cell line 320DM.
Author: Shahzidi, Susan|Stokke, Trond|Soltani, Hela|Nesland, Jahn M|Peng, Qian
PMID: 16566715
Journal: J Biol Chem. 2006 Jun 30;281(26):17599-611. Epub 2006 Apr 14.
Title: Caspase-2 triggers Bax-Bak-dependent and -independent cell death in colon cancer cells treated with resveratrol.
Author: Mohan, John|Gandhi, Alankaram Arul|Bhavya, Balan Chandrika|Rashmi, Ramachandran|Karunagaran, Devarajan|Indu, Ramachandran|Santhoshkumar, Thankayyan Ratnabhai
PMID: 16617056
Journal: Mol Carcinog. 2006 Jul;45(7):461-78.
Title: Checkpoint kinase 1-mediated phosphorylation of Cdc25C and bad proteins are involved in antitumor effects of loratadine-induced G2/M phase cell-cycle arrest and apoptosis.
Author: Chen, Jinn-Shiun|Lin, Shyr-Yi|Tso, Wei-Ling|Yeh, Geng-Chang|Lee, Wen-Sen|Tseng, How|Chen, Li-Ching|Ho, Yuan-Soon
PMID: 16649252
Journal: APMIS. 2006 Apr;114(4):292-7.
Title: Mutational analysis of proapoptotic caspase-9 gene in common human carcinomas.
Author: Soung, Young Hwa|Lee, Jong Woo|Kim, Su Young|Park, Won Sang|Nam, Suk Woo|Lee, Jung Young|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 16689829
Journal: J Gastroenterol Hepatol. 2006 Jan;21(1 Pt 1):84-91.
Title: Fas-associated phosphatase-1 promotes Fas-mediated apoptosis in human colon cancer cells: novel function of FAP-1.
Author: Miyazaki, Takako|Atarashi, Yoshinari|Yasumura, Satoshi|Minatoya, Isao|Ogawa, Kohei|Iwamoto, Masaya|Minemura, Masami|Shimizu, Yukihiro|Sato, Taka-Aki|Watanabe, Akiharu|Sugiyama, Toshiro
PMID: 16706817
Journal: Chin J Physiol. 2006 Apr 30;49(2):110-6.
Title: Apoptotic effects of over-expressed estrogen receptor-beta on LoVo colon cancer cell is mediated by p53 signalings in a ligand-dependent manner.
Author: Hsu, Hsi-Hsien|Cheng, Sue-Fei|Wu, Cheng-Chung|Chu, Chun-Hsien|Weng, Yi-Jiun|Lin, Chung-Sheng|Lee, Shin-Da|Wu, Hung-Chien|Huang, Chih-Yang|Kuo, Wei-Wen
PMID: 16830793
Journal: Oncogene. 2006 Oct 26;25(50):6582-94.
Title: Bak functionally complements for loss of Bax during p14ARF-induced mitochondrial apoptosis in human cancer cells.
Author: Hemmati, P G|Guner, D|Gillissen, B|Wendt, J|von Haefen, C|Chinnadurai, G|Dorken, B|Daniel, P T
PMID: 16847458
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2006 Nov;9(6):519-22.
Title: [Study on the effects of mitochondrial pathways on apoptosis in colon carcinoma cells induced by tumor necrosis factor related apoptosis inducing ligand].
Author: Hao, Ji-hui|Yu, Ming|Li, Qiang|Shi, Yu-rong|Yang, Yi|Hao, Xi-shan
PMID: 17143800
Journal: Cancer Res. 2006 Dec 1;66(23):11254-62.
Title: p21 blocks irradiation-induced apoptosis downstream of mitochondria by inhibition of cyclin-dependent kinase-mediated caspase-9 activation.
Author: Sohn, Dennis|Essmann, Frank|Schulze-Osthoff, Klaus|Janicke, Reiner U
PMID: 17145870
Journal: Exp Mol Med. 2006 Dec 31;38(6):616-24.
Title: Trichostatin A induces apoptosis in lung cancer cells via simultaneous activation of the death receptor-mediated and mitochondrial pathway?
Author: Kim, Hak-Ryul|Kim, Eun-Jung|Yang, Sei-Hoon|Jeong, Eun-Taik|Park, Channy|Lee, Jae-Hyung|Youn, Myung-Ja|So, Hong-Seob|Park, Raekil
PMID: 17202837
Journal: Mol Carcinog. 2007 Mar;46(3):231-41.
Title: Pinocembrin triggers Bax-dependent mitochondrial apoptosis in colon cancer cells.
Author: Kumar, M A Suresh|Nair, Mangalam|Hema, P S|Mohan, John|Santhoshkumar, T R
PMID: 17186548
Journal: Cancer Biol Ther. 2007 Feb;6(2):160-9. Epub 2007 Feb 5.
Title: Lack of p53 augments thymoquinone-induced apoptosis and caspase activation in human osteosarcoma cells.
Author: Roepke, Martin|Diestel, Antje|Bajbouj, Khuloud|Walluscheck, Diana|Schonfeld, Peter|Roessner, Albert|Schneider-Stock, Regine|Gali-Muhtasib, Hala
PMID: 17218778
Journal: Biosci Biotechnol Biochem. 2007 Apr;71(4):1069-72.
Title: Induction of apoptosis in DLD-1 human colon cancer cells by peridinin isolated from the dinoflagellate, Heterocapsa triquetra.
Author: Sugawara, Tatsuya|Yamashita, Kyoko|Sakai, Shota|Asai, Akira|Nagao, Akihiko|Shiraishi, Tomotaka|Imai, Ichiro|Hirata, Takashi
PMID: 17420600
Journal: Mol Cancer Ther. 2007 May;6(5):1562-71.
Title: 5-Aminoimidazole-4-carboxamide riboside sensitizes TRAIL- and TNF{alpha}-induced cytotoxicity in colon cancer cells through AMP-activated protein kinase signaling.
Author: Su, Rong-Ying|Chao, Yee|Chen, Tsai-Yu|Huang, Duen-Yi|Lin, Wan-Wan
PMID: 17513605
Journal: Mol Pharmacol. 2007 Sep;72(3):704-14. Epub 2007 Jun 19.
Title: Low-dose BBR3610 toxicity in colon cancer cells is p53-independent and enhanced by inhibition of epidermal growth factor receptor (ERBB1)-phosphatidyl inositol 3 kinase signaling.
Author: Mitchell, Clint|Kabolizadeh, Peyman|Ryan, John|Roberts, John D|Yacoub, Adly|Curiel, David T|Fisher, Paul B|Hagan, Michael P|Farrell, Nicholas P|Grant, Steven|Dent, Paul
PMID: 17578896
Journal: J Med Food. 2007 Sep;10(3):467-72.
Title: Effect of methanolic extract from silkworm droppings on proliferation and caspase activity in HT-29 human colon cancer cells.
Author: Hwang, Ji-Hwan|Kim, Ju-Young|Cha, Mi-Ran|Park, Hae-Ryong
PMID: 17887940
Journal: J Transl Med. 2007 Oct 30;5:52.
Title: Study of molecular mechanisms of pro-apoptotic activity of NCX 4040, a novel nitric oxide-releasing aspirin, in colon cancer cell lines.
Author: Tesei, Anna|Rosetti, Marco|Ulivi, Paola|Fabbri, Francesco|Medri, Laura|Vannini, Ivan|Bolla, Manlio|Amadori, Dino|Zoli, Wainer
PMID: 17971198
Journal: J Cell Biochem. 2008 Jan 1;103(1):98-109.
Title: Effect of hyperthermia and chemotherapeutic agents on TRAIL-induced cell death in human colon cancer cells.
Author: Yoo, Jinsang|Lee, Yong J
PMID: 17520700
Journal: J Mol Med (Berl). 2008 Jan;86(1):89-98.
Title: Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon.
Author: Izzo, Angelo A|Aviello, Gabriella|Petrosino, Stefania|Orlando, Pierangelo|Marsicano, Giovanni|Lutz, Beat|Borrelli, Francesca|Capasso, Raffaele|Nigam, Santosh|Capasso, Francesco|Di Marzo, Vincenzo
PMID: 17823781
Journal: Carcinogenesis. 2008 Feb;29(2):371-80. Epub 2007 Nov 21.
Title: Licofelone, a dual COX/5-LOX inhibitor, induces apoptosis in HCA-7 colon cancer cells through the mitochondrial pathway independently from its ability to affect the arachidonic acid cascade.
Author: Tavolari, Simona|Bonafe, Massimiliano|Marini, Marina|Ferreri, Carla|Bartolini, Giovanna|Brighenti, Elisa|Manara, Sonia|Tomasi, Vittorio|Laufer, Stefan|Guarnieri, Tiziana
PMID: 18033773
Journal: J Agric Food Chem. 2008 Feb 13;56(3):875-83.
Title: Cytotoxic and antioxidant activity of 4-methylthio-3-butenyl isothiocyanate from Raphanus sativus L. (Kaiware Daikon) sprouts.
Author: Papi, Alessio|Orlandi, Marina|Bartolini, Giovanna|Barillari, Jessica|Iori, Renato|Paolini, Moreno|Ferroni, Fiammetta|Grazia Fumo, Maria|Pedulli, Gian Franco|Valgimigli, Luca
PMID: 18189352
Journal: Eur J Pharmacol. 2008 Mar 17;582(1-3):17-25.
Title: Growth inhibitory effects of obovatol through induction of apoptotic cell death in prostate and colon cancer by blocking of NF-kappaB.
Author: Lee, So Yong|Yuk, Dong Yeon|Song, Ho Seub|Yoon, Do Young|Jung, Jae Kyung|Moon, Dong Cheul|Lee, Byung Seok|Hong, Jin Tae
PMID: 18241858
Journal: Cancer Res. 2008 Feb 1;68(3):909-17.
Title: DR5 receptor mediates anoikis in human colorectal carcinoma cell lines.
Author: Laguinge, Luciana M|Samara, Raed N|Wang, Wenge|El-Deiry, Wafik S|Corner, Georgia|Augenlicht, Leonard|Mishra, Lopa|Jessup, J Milburn
PMID: 18245494
Journal: Mol Cancer. 2008 Feb 8;7:17.
Title: Inducing apoptosis of human colon cancer cells by an IGF-I D domain analogue peptide.
Author: Yang, Shi Yu|Sales, Kevin M|Fuller, Barry J|Seifalian, Alexander M|Winslet, Marc C
PMID: 18261206
Journal: Am J Physiol Gastrointest Liver Physiol. 2008 May;294(5):G1235-44.
Title: CUGBP2 downregulation by prostaglandin E2 protects colon cancer cells from radiation-induced mitotic catastrophe.
Author: Natarajan, Gopalan|Ramalingam, Satish|Ramachandran, Ilangovan|May, Randal|Queimado, Lurdes|Houchen, Courtney W|Anant, Shrikant
PMID: 18325984
Journal: Hum Gene Ther. 2008 Apr;19(4):343-53.
Title: Potent antitumor efficacy of ST13 for colorectal cancer mediated by oncolytic adenovirus via mitochondrial apoptotic cell death.
Author: Yang, Min|Cao, Xin|Yu, Ming Can|Gu, Jin Fa|Shen, Zong Hou|Ding, Miao|Yu, De Bing|Zheng, Shu|Liu, Xin yuan
PMID: 18355116
Journal: Cancer Lett. 2008 Aug 8;266(2):209-15.
Title: Signaling and regulatory mechanisms of integrin alphavbeta6 on the apoptosis of colon cancer cells.
Author: Zhao-Yang, Zhang|Ke-Sen, Xu|Qing-Si, He|Wei-Bo, Niu|Jia-Yong, Wang|Yue-Tang, Mi|Jin-Shen, Wang|Guo-Qiang, Wang|Guang-Yun, Yang|Jun, Niu
PMID: 18381232
Journal: Anticancer Res. 2008 Mar-Apr;28(2A):1045-54.
Title: Crude extracts of Solanum lyratum induced cytotoxicity and apoptosis in a human colon adenocarcinoma cell line (colo 205).
Author: Hsu, Shu-Chun|Lu, Jih-Hung|Kuo, Chao-Lin|Yang, Jai-Sing|Lin, Meng-Wei|Chen, Guang-Wei|Su, Chin-Cheng|Lu, Hsu-Fung|Chung, Jing-Gung
PMID: 18507053
Journal: Carcinogenesis. 2008 Jul;29(7):1407-14.
Title: PPARgamma is involved in mesalazine-mediated induction of apoptosis and inhibition of cell growth in colon cancer cells.
Author: Schwab, Markus|Reynders, Veerle|Loitsch, Stefan|Shastri, Yogesh M|Steinhilber, Dieter|Schroder, Oliver|Stein, Jurgen
PMID: 18544567
Journal: Oncogene. 2008 Oct 9;27(46):6012-22.
Title: A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma.
Author: Ndozangue-Touriguine, O|Sebbagh, M|Merino, D|Micheau, O|Bertoglio, J|Breard, J
PMID: 18560353
Journal: Zhonghua Zhong Liu Za Zhi. 2008 Apr;30(4):245-9.
Title: [Overcoming acquired resistance to tumor necrosis factor-related apoptosis-inducing ligand by Bcl-XL small interfering RNA in human colon cancer].
Author: Zhu, Hong-Bo|Huang, Xue-Feng|Hu, Jing-Zi|Zhou, Wei|Chen, Wei|Chen, Lin-Lin|He, Chao
PMID: 18788624
Journal: Ai Zheng. 2008 Sep;27(9):929-33.
Title: [Role of high mobility group box 1 in adriamycin-induced apoptosis in leukemia K562 cells].
Author: Yu, Yan|Xie, Min|He, Yu-Lei|Xu, Wang-Qiong|Zhu, Shan|Cao, Li-Zhi
PMID: 18799030
Journal: Exp Biol Med (Maywood). 2008 Dec;233(12):1554-60.
Title: Hexane/ethanol extract of Glycyrrhiza uralensis licorice suppresses doxorubicin-induced apoptosis in H9c2 rat cardiac myoblasts.
Author: Choi, Hyun Ju|Seon, Mi Ra|Lim, Soon Sung|Kim, Jong-Sang|Chun, Hyang Sook|Park, Jung Han Yoon
PMID: 18849542
Journal: Clin Cancer Res. 2008 Dec 15;14(24):8132-42.
Title: Induction of Noxa sensitizes human colorectal cancer cells expressing Mcl-1 to the small-molecule Bcl-2/Bcl-xL inhibitor, ABT-737.
Author: Okumura, Kenji|Huang, Shengbing|Sinicrope, Frank A
PMID: 19088028
Journal: Cancer Lett. 2009 Jan 8;273(1):44-54.
Title: Maslinic acid, a natural triterpene from Olea europaea L., induces apoptosis in HT29 human colon-cancer cells via the mitochondrial apoptotic pathway.
Author: Reyes-Zurita, Fernando J|Rufino-Palomares, Eva E|Lupianez, Jose A|Cascante, Marta
PMID: 18790561
Journal: J Surg Res. 2009 May 15;153(2):246-53.
Title: Plaunotol and geranylgeraniol induce caspase-mediated apoptosis in colon cancer.
Author: Yoshikawa, Naoyuki|Yamada, Jun|Tsuno, Nelson H|Okaji, Yurai|Kawai, Kazushige|Tsuchiya, Takeshi|Yoneyama, Satomi|Tanaka, Junichiro|Shuno, Yasutaka|Nishikawa, Takeshi|Nagawa, Hirokazu|Oshima, Noriko|Takahashi, Koki
PMID: 18805546
Journal: Food Chem Toxicol. 2009 Feb;47(2):377-85.
Title: Age-related differential responses to curcumin-induced apoptosis during the initiation of colon cancer in rats.
Author: Kwon, Youngjoo|Magnuson, Bernadene A
PMID: 19095035
Journal: Cancer Sci. 2009 Mar;100(3):503-13.
Title: Formosanin C-induced apoptosis requires activation of caspase-2 and change of mitochondrial membrane potential.
Author: Lee, Jenq-Chang|Su, Chun-Li|Chen, Lin-Lin|Won, Shen-Jeu
PMID: 19154411
Journal: Nutr Cancer. 2009;61(3):374-80.
Title: Biphasic regulation of cell death and survival by hydrophobic bile acids in HCT116 cells.
Author: Yui, Satoko|Kanamoto, Ryuhei|Saeki, Tohru
PMID: 19373611
Journal: Mol Pharmacol. 2009 Aug;76(2):342-55.
Title: Sorafenib and vorinostat kill colon cancer cells by CD95-dependent and -independent mechanisms.
Author: Walker, Teneille|Mitchell, Clint|Park, Margaret A|Yacoub, Adly|Graf, Martin|Rahmani, Mohamed|Houghton, Peter J|Voelkel-Johnson, Christina|Grant, Steven|Dent, Paul
PMID: 19483104
Journal: Proteomics. 2009 Jul;9(13):3535-48.
Title: Novel functional profiling approach combining reverse phase protein microarrays and human 3-D ex vivo tissue cultures: expression of apoptosis-related proteins in human colon cancer.
Author: Pirnia, Farzaneh|Pawlak, Michael|Thallinger, Gerhard G|Gierke, Berthold|Templin, Markus F|Kappeler, Andi|Betticher, Daniel C|Gloor, Beat|Borner, Markus M
PMID: 19609961
Journal: Anticancer Drugs. 2009 Oct;20(9):815-21.
Title: A novel histone deacetylase inhibitor, CG0006, induces cell death through both extrinsic and intrinsic apoptotic pathways.
Author: Hwang, Jung Jin|Kim, Yong Sook|Kim, Mi Joung|Jang, Sejin|Lee, Je-Hwan|Choi, Jene|Ro, Seonggu|Hyun, Young-Lan|Lee, Jung Shin|Kim, Choung-Soo
PMID: 19644355
Journal: J Zhejiang Univ Sci B. 2009 Sep;10(9):668-74.
Title: Ursolic acid inhibits proliferation and induces apoptosis of HT-29 colon cancer cells by inhibiting the EGFR/MAPK pathway.
Author: Shan, Jian-zhen|Xuan, Yan-yan|Zheng, Shu|Dong, Qi|Zhang, Su-zhan
PMID: 19735099
Journal: Oncogene. 2009 Dec 17;28(50):4421-33.
Title: A novel pro-apoptotic function of RACK1: suppression of Src activity in the intrinsic and Akt pathways.
Author: Mamidipudi, V|Cartwright, C A
PMID: 19767770
Journal: Biol Pharm Bull. 2009 Oct;32(10):1760-4.
Title: Apoptosis inducing activity of fucoidan in HCT-15 colon carcinoma cells.
Author: Hyun, Jae-Hee|Kim, Sang-Cheol|Kang, Jung-Il|Kim, Min-Kyoung|Boo, Hye-Jin|Kwon, Jung-Mi|Koh, Young-Sang|Hyun, Jin-Won|Park, Deok-Bae|Yoo, Eun-Sook|Kang, Hee-Kyoung
PMID: 19801840
Journal: J Agric Food Chem. 2009 Nov 25;57(22):10573-8.
Title: Compound K induces apoptosis via CAMK-IV/AMPK pathways in HT-29 colon cancer cells.
Author: Kim, Do Yeon|Park, Min Woo|Yuan, Hai Dan|Lee, Hyo Jung|Kim, Sung Hoon|Chung, Sung Hyun
PMID: 19845353
Journal: J Med Food. 2009 Oct;12(5):952-8.
Title: trans-10,cis-12 Conjugated linoleic acid induces depolarization of mitochondrial membranes in HT-29 human colon cancer cells: a possible mechanism for induction of apoptosis.
Author: Cho, Han Jin|Kwon, Gyoo Taik|Park, Jung Han Yoon
PMID: 19857056
Journal: J Agric Food Chem. 2009 Dec 9;57(23):11383-90.
Title: Novel anticancer activity of the autocleaved ovotransferrin against human colon and breast cancer cells.
Author: Ibrahim, Hisham R|Kiyono, Tohru
PMID: 19886663
Journal: Mol Cancer. 2009 Nov 12;8:100.
Title: A combination of indol-3-carbinol and genistein synergistically induces apoptosis in human colon cancer HT-29 cells by inhibiting Akt phosphorylation and progression of autophagy.
Author: Nakamura, Yoshitaka|Yogosawa, Shingo|Izutani, Yasuyuki|Watanabe, Hirotsuna|Otsuji, Eigo|Sakai, Tosiyuki
PMID: 19909554
Journal: Oncol Res. 2009;18(1):1-8.
Title: The anticancer effects of sodium selenite and selenomethionine on human colorectal carcinoma cell lines in nude mice.
Author: Yang, Yang|Huang, Fang|Ren, Yun|Xing, Lu|Wu, Ying|Li, Zhushi|Pan, Huazhen|Xu, Caimin
PMID: 19911698
Journal: Mol Med Rep. 2009 Jul-Aug;2(4):627-31.
Title: Curcumin induces caspase and calpain-dependent apoptosis in HT29 human colon cancer cells.
Author: Singh, Nisha|Shrivastav, Anuraag|Sharma, Rajendra K
PMID: 21475877
Journal: Mol Carcinog. 2010 Apr;49(4):324-36.
Title: Lysosomal destabilization and cathepsin B contributes for cytochrome c release and caspase activation in embelin-induced apoptosis.
Author: Joy, Beena|Sivadasan, Rajeeve|Abraham T, Emilia|John, Mohan|Sobhan, Praveen K|Seervi, Mahendra|T R, Santhoshkumar
PMID: 19943316
Journal: Int J Cancer. 2010 Aug 15;127(4):873-80.
Title: Expression and prognostic significance of APAF-1, caspase-8 and caspase-9 in stage II/III colon carcinoma: caspase-8 and caspase-9 is associated with poor prognosis.
Author: Strater, Jorn|Herter, Ines|Merkel, Gaby|Hinz, Ulf|Weitz, Jurgen|Moller, Peter
PMID: 20013803
Journal: Biochem Pharmacol. 2010 Jun 15;79(12):1759-71.
Title: Modulation of stress genes expression profile by nitric oxide-releasing aspirin in Jurkat T leukemia cells.
Author: Nath, Niharika|Chattopadhyay, Mitali|Kodela, Ravinder|Tian, Song|Vlismas, Peter|Boring, Daniel|Crowell, James A|Kashfi, Khosrow
PMID: 20188076
Journal: Chem Biol Interact. 2010 May 14;185(3):182-8.
Title: Role of fatty acid chain length on the induction of apoptosis by newly synthesized catechin derivatives.
Author: Ahmed, Kanwal|Wei, Zheng-Li|Zhao, Qing-Li|Nakajima, Noriyuki|Matsunaga, Takayuki|Ogasawara, Masaru|Kondo, Takashi
PMID: 20206613
Journal: J Cell Physiol. 2010 Jul;224(1):33-40.
Title: Arctigenin blocks the unfolded protein response and shows therapeutic antitumor activity.
Author: Kim, Ju-Young|Hwang, Ji-Hwan|Cha, Mi-Ran|Yoon, Mi-Young|Son, Eun-Soon|Tomida, Akihiro|Ko, Bosung|Song, Si-Whan|Shin-ya, Kazuo|Hwang, Yong-il|Park, Hae-Ryong
PMID: 20232300
Journal: Biosci Biotechnol Biochem. 2010;74(4):788-92. Epub 2010 Apr 7.
Title: Pleurospermum kamtschaticum extract induces apoptosis via mitochondrial pathway and NAG-1 expression in colon cancer cells.
Author: Kim, Jin-Eun|Chung, Won-Yoon|Chun, Kyung-Soo|Lee, Chang Ki|Park, Hee-Juhn|Kim, Won-Bae|Park, Kwang-Kyun
PMID: 20378978
Journal: J Mol Med (Berl). 2010 Jun;88(6):609-22.
Title: Systematic genetic dissection of p14ARF-mediated mitochondrial cell death signaling reveals a key role for p21CDKN1 and the BH3-only protein Puma/bbc3.
Author: Hemmati, Philipp G|Muer, Annika|Gillissen, Bernd|Overkamp, Tim|Milojkovic, Ana|Wendt, Jana|Dorken, Bernd|Daniel, Peter T
PMID: 20419447
Journal: Chem Biol Interact. 2010 Oct 6;188(1):75-85.
Title: Suppression of NF-kappaB and GSK-3beta is involved in colon cancer cell growth inhibition by the PPAR agonist troglitazone.
Author: Ban, Jung Ok|Kwak, Dong Hoon|Oh, Ju Hoon|Park, Eun-Jung|Cho, Min-Chul|Song, Ho Seub|Song, Min Jong|Han, Sang Bae|Moon, Dong Cheul|Kang, Keon Wook|Hong, Jin Tae
PMID: 20540935
Journal: Oncol Rep. 2010 Aug;24(2):449-55.
Title: Allyl isothiocyanate triggers G2/M phase arrest and apoptosis in human brain malignant glioma GBM 8401 cells through a mitochondria-dependent pathway.
Author: Chen, Nian-Gu|Chen, Kuan-Tin|Lu, Chi-Cheng|Lan, Yu-Hsuan|Lai, Cheng-Hung|Chung, Yang-Tsung|Yang, Jai-Sing|Lin, Yung-Chang
PMID: 20596632
Journal: Toxicol In Vitro. 2010 Sep;24(6):1546-53.
Title: A glycoprotein from Laminaria japonica induces apoptosis in HT-29 colon cancer cells.
Author: Go, Hiroe|Hwang, Hye-Jung|Nam, Taek-Jeong
PMID: 20615460
Journal: Tumour Biol. 2010 Dec;31(6):623-31.
Title: PI3-kinase/Wnt association mediates COX-2/PGE(2) pathway to inhibit apoptosis in early stages of colon carcinogenesis: chemoprevention by diclofenac.
Author: Kaur, Jasmeet|Sanyal, Sankar Nath
PMID: 20617408
Journal: Anticancer Drugs. 2010 Sep;21(8):766-76.
Title: Evodiamine induces caspase-dependent apoptosis and S phase arrest in human colon lovo cells.
Author: Zhang, Chun|Fan, Xia|Xu, Xiang|Yang, Xue|Wang, Xi|Liang, Hua-Ping
PMID: 20647931
Journal: Chin Med. 2010 Jul 21;5:25.
Title: Tian Xian Liquid (TXL) induces apoptosis in HT-29 colon cancer cell in vitro and inhibits tumor growth in vivo.
Author: Liu, Qing|Tong, Yao|Sze, Stephen Cho Wing|Liu, Wing Keung|Lam, Lam|Chu, Ellie Shihng Meir|Yow, Christine Miu Ngan
PMID: 20663169
Journal: Anticancer Drugs. 2010 Oct;21(9):850-60.
Title: Isoprenoid geranylgeranylacetone inhibits human colon cancer cells through induction of apoptosis and cell cycle arrest.
Author: Yoshikawa, Naoyuki|Tsuno, Nelson H|Okaji, Yurai|Kawai, Kazushige|Shuno, Yasutaka|Nagawa, Hirokazu|Oshima, Noriko|Takahashi, Koki
PMID: 20724917
Journal: BMC Gastroenterol. 2010 Aug 22;10:96.
Title: Fucoidan present in brown algae induces apoptosis of human colon cancer cells.
Author: Kim, Eun Ji|Park, So Young|Lee, Jae-Yong|Park, Jung Han Yoon
PMID: 20727207
Journal: Bioorg Med Chem Lett. 2010 Dec 1;20(23):7110-5.
Title: Oleanane-type triterpenoids from Panax stipuleanatus and their anticancer activities.
Author: Liang, Chun|Ding, Yan|Nguyen, Huu Tung|Kim, Jeong-Ah|Boo, Hye-Jin|Kang, Hee-Kyoung|Nguyen, Mahn Cuong|Kim, Young Ho
PMID: 20951582
Journal: Mol Med Rep. 2010 Sep-Oct;3(5):825-31.
Title: 20(S)-Ginsenoside Rg3-induced apoptosis in HT-29 colon cancer cells is associated with AMPK signaling pathway.
Author: Yuan, Hai-Dan|Quan, Hai-Yan|Zhang, Ya|Kim, Sung Hoon|Chung, Sung-Hyun
PMID: 21472321
Journal: Int J Mol Sci. 2010;11(12):4916-31.
Title: Compound K, a metabolite of ginseng saponin, induces mitochondria-dependent and caspase-dependent apoptosis via the generation of reactive oxygen species in human colon cancer cells.
Author: Lee, In Kyung|Kang, Kyoung Ah|Lim, Chae Moon|Kim, Ki Cheon|Kim, Hee Sun|Kim, Dong Hyun|Kim, Bum Joon|Chang, Weon Young|Choi, Jae Hyuck|Hyun, Jin Won
PMID: 21614182
Journal: Apoptosis. 2011 Feb;16(2):184-97.
Title: Sequential caspase-2 and caspase-8 activation is essential for saikosaponin a-induced apoptosis of human colon carcinoma cell lines.
Author: Kim, Byeong Mo|Hong, Sung Hee
PMID: 21107704
Journal: J Appl Microbiol. 2011 Jan;110(1):304-13.
Title: Apoptosis-inducing effect of diketopiperazine disulfides produced by Aspergillus sp. KMD 901 isolated from marine sediment on HCT116 colon cancer cell lines.
Author: Choi, E J|Park, J-S|Kim, Y-J|Jung, J-H|Lee, J K|Kwon, H C|Yang, H O
PMID: 21122037
Journal: J Cell Biochem. 2011 Feb;112(2):643-52.
Title: Phloroglucinol derivative MCPP induces cell apoptosis in human colon cancer.
Author: Huang, Ssu-Ming|Cheung, Chi-Wai|Chang, Chih-Shiang|Tang, Chih-Hsin|Liu, Ju-Fang|Lin, Yu-Hsin|Chen, Jia-Hong|Ko, Shihi-Hsun|Wong, Kar-Lok|Lu, Dah-Yuu
PMID: 21268086
Journal: Cell Death Differ. 2011 Nov;18(11):1702-10.
Title: MiR-148a promotes apoptosis by targeting Bcl-2 in colorectal cancer.
Author: Zhang, H|Li, Y|Huang, Q|Ren, X|Hu, H|Sheng, H|Lai, M
PMID: 21455217
Journal: Cell Physiol Biochem. 2011;27(3-4):233-42.
Title: Deltonin, a steroidal saponin, inhibits colon cancer cell growth in vitro and tumor growth in vivo via induction of apoptosis and antiangiogenesis.
Author: Tong, Qing-Yi|Qing, Yong|Shu, Dan|He, Yang|Zhao, Ying-Lan|Li, Yi|Wang, Zhen-Ling|Zhang, Shi-Yuan|Xing, Zhi-hua|Xu, Cheng|Wei, Yu-Quan|Huang, Wen|Wu, Xiao-Hua
PMID: 21471712
Journal: Biochem Cell Biol. 2011 Jun;89(3):287-98.
Title: LYG-202 inhibits the proliferation of human colorectal carcinoma HCT-116 cells through induction of G1/S cell cycle arrest and apoptosis via p53 and p21(WAF1/Cip1) expression.
Author: Liu, Wei|Dai, Qinsheng|Lu, Na|Wei, Libin|Ha, Jun|Rong, Jingjing|Mu, Rong|You, Qidong|Li, Zhiyu|Guo, Qinglong
PMID: 21491996
Journal: Food Chem Toxicol. 2011 Jul;49(7):1616-25.
Title: Obacunone and obacunone glucoside inhibit human colon cancer (SW480) cells by the induction of apoptosis.
Author: Chidambara Murthy, K N|Jayaprakasha, G K|Patil, Bhimanagouda S
PMID: 21515332
Journal: BMC Cancer. 2011 Apr 27;11:154.
Title: The natural triterpene maslinic acid induces apoptosis in HT29 colon cancer cells by a JNK-p53-dependent mechanism.
Author: Reyes-Zurita, Fernando J|Pachon-Pena, Gisela|Lizarraga, Daneida|Rufino-Palomares, Eva E|Cascante, Marta|Lupianez, Jose A
PMID: 21524306
Journal: Int J Colorectal Dis. 2011 Sep;26(9):1113-8.
Title: Polymorphisms of caspase 8 and caspase 9 gene and colorectal cancer susceptibility and prognosis.
Author: Theodoropoulos, George E|Gazouli, Maria|Vaiopoulou, Anna|Leandrou, Myrto|Nikouli, Sofia|Vassou, Efthimia|Kouraklis, Gregory|Nikiteas, Nikolaos
PMID: 21538054
Journal: World J Gastroenterol. 2011 Apr 28;17(16):2086-95.
Title: Effects of alpha-mangostin on apoptosis induction of human colon cancer.
Author: Watanapokasin, Ramida|Jarinthanan, Faongchat|Nakamura, Yukio|Sawasjirakij, Nitisak|Jaratrungtawee, Amornmart|Suksamrarn, Sunit
PMID: 21547127
Journal: Biomed Pharmacother. 2011 Jun;65(3):175-82.
Title: Concomitant activation of caspase-9 and down-regulation of IAP proteins as a mechanism of apoptotic death in HepG2, T47D and HCT-116 cells upon exposure to a derivative from 4-aryl-4H-chromenes family.
Author: Mahdavi, Majid|Davoodi, Jamshid|Zali, Mohammad Reza|Foroumadi, Alireza
PMID: 21565459
Journal: Biomed Pharmacother. 2011 Jun;65(3):137-41.
Title: Lobaplatin suppresses proliferation and induces apoptosis in the human colorectal carcinoma cell Line LOVO in vitro.
Author: Dai, Hong-yu|Liu, Lin|Qin, Shu-kui|He, Xiang-ming|Li, Su-yi
PMID: 21612887
Journal: PLoS One. 2011;6(5):e20276.
Title: Calbindin 2 (CALB2) regulates 5-fluorouracil sensitivity in colorectal cancer by modulating the intrinsic apoptotic pathway.
Author: Stevenson, Leanne|Allen, Wendy L|Proutski, Irina|Stewart, Gail|Johnston, Louise|McCloskey, Karen|Wilson, Peter M|Longley, Daniel B|Johnston, Patrick G
PMID: 21629658
Journal: Zhejiang Da Xue Xue Bao Yi Xue Ban. 2011 May;40(3):245-51.
Title: [Expression of caspase apoptosis pathway genes mRNA in colorectal cancer and polyps].
Author: Pan, Yi-feng|Zhang, Ming-wu|Jin, Ming-juan|Zhang, Shan-chun|Chen, Kun|Li, Qi-long|Ma, Xin-yuan|Yao, Kai-yan|Yu, Yun-xian
PMID: 21671482
Journal: Gastroenterology. 2011 Aug;141(2):663-73.
Title: Oxaliplatin sensitizes human colon cancer cells to TRAIL through JNK-dependent phosphorylation of Bcl-xL.
Author: El Fajoui, Zineb|Toscano, Florent|Jacquemin, Guillaume|Abello, Jacques|Scoazec, Jean-Yves|Micheau, Olivier|Saurin, Jean-Christophe
PMID: 21683075
Journal: Hum Cell. 2011 Sep;24(3):121-6.
Title: Enormous influence of TNIK knockdown on intracellular signals and cell survival.
Author: Gui, Jinghua|Yang, Baotian|Wu, Jinyun|Zhou, Xiumei
PMID: 21710359
Journal: Apoptosis. 2011 Oct;16(10):1054-67.
Title: Deoxycholic and chenodeoxycholic bile acids induce apoptosis via oxidative stress in human colon adenocarcinoma cells.
Author: Ignacio Barrasa, Juan|Olmo, Nieves|Perez-Ramos, Pablo|Santiago-Gomez, Angelica|Lecona, Emilio|Turnay, Javier|Antonia Lizarbe, M
PMID: 21789651
Journal: Toxicology. 2011 Dec 18;290(2-3):230-40.
Title: Mechanism of Alternariol monomethyl ether-induced mitochondrial apoptosis in human colon carcinoma cells.
Author: Bensassi, Fatma|Gallerne, Cindy|el Dein, Ossama Sharaf|Hajlaoui, Mohamed Rabeh|Bacha, Hassen|Lemaire, Christophe
PMID: 22001388
Journal: BMC Cancer. 2011 Nov 14;11:485.
Title: Small interfering RNA targeting mcl-1 enhances proteasome inhibitor-induced apoptosis in various solid malignant tumors.
Author: Zhou, Wei|Hu, Jingzi|Tang, Haimei|Wang, Da|Huang, Xuefeng|He, Chao|Zhu, Hongbo
PMID: 22078414
Journal: Int J Stem Cells. 2011 Jun;4(1):70-5.
Title: Human Embryonic-like ECM (hECM) Stimulates Proliferation and Differentiation in Stem Cells While Killing Cancer Cells.
Author: Pinney, Emmett|Zimber, Michael|Schenone, Aaron|Montes-Camacho, Mayra|Ziegler, Frank|Naughton, Gail K
PMID: 24298336
Journal: Br J Pharmacol. 2012 Feb;165(3):741-53.
Title: Cardamonin sensitizes tumour cells to TRAIL through ROS- and CHOP-mediated up-regulation of death receptors and down-regulation of survival proteins.
Author: Yadav, Vivek R|Prasad, Sahdeo|Aggarwal, Bharat B
PMID: 21797841
Journal: Cell Biol Int. 2012 Mar 1;36(3):289-96.
Title: PEG-liposomal oxaliplatin induces apoptosis in human colorectal cancer cells via Fas/FasL and caspase-8.
Author: Yang, Chuang|Liu, Hai-Zhong|Fu, Zhong-Xue
PMID: 21888623
Journal: Int J Toxicol. 2012 Jan-Feb;31(1):70-7.
Title: Sanguinarine induces apoptosis of HT-29 human colon cancer cells via the regulation of Bax/Bcl-2 ratio and caspase-9-dependent pathway.
Author: Lee, Jun Sik|Jung, Won-Kyo|Jeong, Myung Ho|Yoon, Taek Rim|Kim, Hyung Keun
PMID: 22215411
Journal: Apoptosis. 2012 May;17(5):528-37.
Title: Targeting colorectal cancer stem cells with inducible caspase-9.
Author: Kemper, Kristel|Rodermond, Hans|Colak, Selcuk|Grandela, Catarina|Medema, Jan Paul
PMID: 22223359
Journal: Oncol Rep. 2012 May;27(5):1407-12.
Title: Widdrol induces apoptosis via activation of AMP-activated protein kinase in colon cancer cells.
Author: Kang, Moo Rim|Park, Song-Kyu|Lee, Chang Woo|Cho, Ig Jun|Jo, Yeong Nang|Yang, Jeong Wook|Kim, Jin-Ah|Yun, Jieun|Lee, Ki Hoon|Kwon, Hyun Ju|Kim, Byung Woo|Lee, Kiho|Kang, Jong Soon|Kim, Hwan Mook
PMID: 22266984
Journal: Toxicol In Vitro. 2012 Apr;26(3):414-20.
Title: A mitochondria-mediated apoptotic pathway induced by deoxynivalenol in human colon cancer cells.
Author: Ma, Yanna|Zhang, Aihua|Shi, Zhiyu|He, Chenghua|Ding, Jujing|Wang, Xichun|Ma, Jifei|Zhang, Haibin
PMID: 22269384
Journal: Int J Nanomedicine. 2012;7:95-107.
Title: 5-Fluorouracil-loaded poly(epsilon-caprolactone) nanoparticles combined with phage E gene therapy as a new strategy against colon cancer.
Author: Ortiz, Raul|Prados, Jose|Melguizo, Consolacion|Arias, Jose L|Ruiz, M Adolfina|Alvarez, Pablo J|Caba, Octavio|Luque, Raquel|Segura, Ana|Aranega, Antonia
PMID: 22275826
Journal: Mol Med Rep. 2012 Apr;5(4):1037-42.
Title: Silencing of the polyamine catabolic key enzyme SSAT prevents CDK inhibitor-induced apoptosis in Caco-2 colon cancer cells.
Author: Coker, A|Arisan, E D|Palavan-Unsal, N
PMID: 22294330
Journal: Food Chem Toxicol. 2012 May;50(5):1271-8.
Title: Antitumor effects of emodin on LS1034 human colon cancer cells in vitro and in vivo: roles of apoptotic cell death and LS1034 tumor xenografts model.
Author: Ma, Yi-Shih|Weng, Shu-Wen|Lin, Meng-Wei|Lu, Chi-Cheng|Chiang, Jo-Hua|Yang, Jai-Sing|Lai, Kuang-Chi|Lin, Jing-Pin|Tang, Nou-Ying|Lin, Jaung-Geng|Chung, Jing-Gung
PMID: 22321733
Journal: Food Chem Toxicol. 2012 May;50(5):1560-7.
Title: Paeoniflorin inhibits growth of human colorectal carcinoma HT 29 cells in vitro and in vivo.
Author: Wang, He|Zhou, Hong|Wang, Cheng-Xi|Li, Yue-Shan|Xie, Hong-Yan|Luo, Jian-Dong|Zhou, Yi
PMID: 22326807
Journal: Nutr Cancer. 2012 Apr;64(3):409-18.
Title: Piroxicam and C-phycocyanin mediated apoptosis in 1,2-dimethylhydrazine dihydrochloride induced colon carcinogenesis: exploring the mitochondrial pathway.
Author: Saini, Manpreet Kaur|Sanyal, Sankar Nath|Vaiphei, Kim
PMID: 22369161
Journal: Int J Oncol. 2012 Jun;40(6):1970-6.
Title: Ginsenoside compound K, not Rb1, possesses potential chemopreventive activities in human colorectal cancer.
Author: Wang, Chong-Zhi|Du, Guang-Jian|Zhang, Zhiyu|Wen, Xiao-Dong|Calway, Tyler|Zhen, Zhong|Musch, Mark W|Bissonnette, Marc|Chang, Eugene B|Yuan, Chun-Su
PMID: 22426808
Journal: FASEB J. 2012 Jul;26(7):2764-75.
Title: Loss of giant obscurins promotes breast epithelial cell survival through apoptotic resistance.
Author: Perry, Nicole A|Shriver, Marey|Mameza, Marie G|Grabias, Bryan|Balzer, Eric|Kontrogianni-Konstantopoulos, Aikaterini
PMID: 22441987
Journal: J Pharm Pharmacol. 2012 May;64(5):727-34.
Title: Caspase-mediated pro-apoptotic interaction of panaxadiol and irinotecan in human colorectal cancer cells.
Author: Du, Guang-Jian|Wang, Chong-Zhi|Zhang, Zhi-Yu|Wen, Xiao-Dong|Somogyi, Jacqueline|Calway, Tyler|He, Tong-Chuan|Du, Wei|Yuan, Chun-Su
PMID: 22471369
Journal: Nutr Cancer. 2012;64(4):617-26.
Title: Ursodeoxycholic acid protects colon cancer HCT116 cells from deoxycholic acid-induced apoptosis by inhibiting apoptosome formation.
Author: Saeki, Tohru|Yui, Satoko|Hirai, Tadashi|Fujii, Takami|Okada, Sawami|Kanamoto, Ryuhei
PMID: 22497644
Journal: Cancer Res Treat. 2012 Mar;44(1):32-6.
Title: Prognostic Impact of Polymorphisms in the CASPASE Genes on Survival of Patients with Colorectal Cancer.
Author: Choi, Jun Young|Kim, Jong Gwang|Lee, You Jin|Chae, Yee Soo|Sohn, Sang Kyun|Moon, Joon Ho|Kang, Byung Woog|Jung, Min Kyu|Jeon, Seong Woo|Park, Jun Seok|Choi, Gyu Seog
PMID: 22500158
Journal: Anticancer Drugs. 2012 Jul;23(6):651-8.
Title: The role of Nrf2 and apoptotic signaling pathways in oroxylin A-mediated responses in HCT-116 colorectal adenocarcinoma cells and xenograft tumors.
Author: Hu, Rong|Chen, Nan|Yao, Jing|Zhao, Qing|Zhang, Fengyi|Li, Zhi-Yu|You, Qi-Dong|Guo, Qing-Long
PMID: 22526619
Journal: World J Gastroenterol. 2012 Apr 14;18(14):1590-601.
Title: Overexpression of Dickkopf-3 induces apoptosis through mitochondrial pathway in human colon cancer.
Author: Yang, Zi-Rong|Dong, Wei-Guo|Lei, Xiao-Fei|Liu, Meng|Liu, Qi-Sheng
PMID: 22529687
Journal: Toxicol In Vitro. 2012 Sep;26(6):915-23.
Title: Cell death induced by the Alternaria mycotoxin Alternariol.
Author: Bensassi, Fatma|Gallerne, Cindy|Sharaf El Dein, Ossama|Hajlaoui, Mohamed Rabeh|Bacha, Hassen|Lemaire, Christophe
PMID: 22542754
Journal: Biochem Biophys Res Commun. 2012 May 11;421(3):627-33.
Title: Noscapine induces mitochondria-mediated apoptosis in human colon cancer cells in vivo and in vitro.
Author: Yang, Zi-Rong|Liu, Meng|Peng, Xiu-Lan|Lei, Xiao-Fei|Zhang, Ji-Xiang|Dong, Wei-Guo
PMID: 22546556
Journal: Oncol Rep. 2012 Sep;28(3):949-54.
Title: Diallyl trisulfide induces apoptosis in human primary colorectal cancer cells.
Author: Yu, Chun-Shu|Huang, An-Cheng|Lai, Kuang-Chi|Huang, Yi-Ping|Lin, Meng-Wei|Yang, Jai-Sing|Chung, Jing-Gung
PMID: 22736270
Journal: Anticancer Res. 2012 Jul;32(7):2855-62.
Title: Anti-invasive effects and proapoptotic activity induction by the rexinoid IIF and valproic acid in combination on colon cancer cell lines.
Author: Papi, A|Ferreri, A M|Guerra, F|Orlandi, M
PMID: 22753748
Journal: Microb Pathog. 2012 Sep;53(3-4):147-53.
Title: Escherichia coli STb toxin induces apoptosis in intestinal epithelial cell lines.
Author: Syed, H Claudia|Dubreuil, J Daniel
PMID: 22771838
Journal: Int J Nanomedicine. 2012;7:4109-18.
Title: Synergistic effect of a combination of nanoparticulate Fe3O4 and gambogic acid on phosphatidylinositol 3-kinase/Akt/Bad pathway of LOVO cells.
Author: Fang, Lianghua|Chen, Baoan|Liu, Shenlin|Wang, Ruiping|Hu, Shouyou|Xia, Guohua|Tian, Yongli|Cai, Xiaohui
PMID: 22888247
Journal: Molecules. 2012 Aug 20;17(8):9947-60.
Title: Laminarin induces apoptosis of human colon cancer LOVO cells through a mitochondrial pathway.
Author: Ji, Yu Bin|Ji, Chen Feng|Zhang, He
PMID: 22907156
Journal: Int J Mol Med. 2012 Nov;30(5):1087-94.
Title: The synergistic effects of low-dose irinotecan and TRAIL on TRAIL-resistant HT-29 colon carcinoma in vitro and in vivo.
Author: Zhu, Hong|Zhao, Fen|Yu, Shuijing|He, Jianping|Deng, Licong|Yi, Cheng|Huang, Ying
PMID: 22922573
Journal: Int J Oncol. 2012 Nov;41(5):1715-22.
Title: Anticancer effects of KI-10F: a novel compound affecting apoptosis, angiogenesis and cell growth in colon cancer.
Author: Hong, Sang-Won|Jung, Kyung Hee|Choi, Myung-Joo|Kim, Da Young|Lee, Hee-Seung|Zheng, Hong-Mei|Li, Guang Yong|El-Deeb, Ibrahim M|Park, Byung Sun|Lee, So Ha|Hong, Soon-Sun
PMID: 22941304
Journal: J Ethnopharmacol. 2012 Oct 11;143(3):914-9.
Title: Cytotoxic effects of Echinacea purpurea flower extracts and cichoric acid on human colon cancer cells through induction of apoptosis.
Author: Tsai, Yu-Ling|Chiu, Chien-Chih|Yi-Fu Chen, Jeff|Chan, Kung-Chi|Lin, Sheng-Dun
PMID: 22971663
Journal: J Biol Chem. 2012 Nov 30;287(49):41546-59.
Title: Systems analysis of cancer cell heterogeneity in caspase-dependent apoptosis subsequent to mitochondrial outer membrane permeabilization.
Author: Schmid, Jasmin|Dussmann, Heiko|Boukes, Gerhardt J|Flanagan, Lorna|Lindner, Andreas U|O'Connor, Carla L|Rehm, Markus|Prehn, Jochen H M|Huber, Heinrich J
PMID: 23038270
Journal: Life Sci. 2012 Dec 17;91(25-26):1295-303.
Title: Sophoridine exerts an anti-colorectal carcinoma effect through apoptosis induction in vitro and in vivo.
Author: Liang, Lei|Wang, Xiao-Yan|Zhang, Xu-Hui|Ji, Bo|Yan, Hua-Cheng|Deng, Hong-Zhu|Wu, Xin-Rong
PMID: 23069582
Journal: Life Sci. 2012 Dec 17;91(25-26):1336-44.
Title: Phenethyl caffeate benzo[kl]xanthene lignan with DNA interacting properties induces DNA damage and apoptosis in colon cancer cells.
Author: Vijayakurup, Vinod|Carmela, Spatafora|Carmelo, Daquino|Corrado, Tringali|Srinivas, Priya|Gopala, Srinivas
PMID: 23123449
Journal: PLoS One. 2012;7(11):e49605.
Title: Survival of cancer stem cells under hypoxia and serum depletion via decrease in PP2A activity and activation of p38-MAPKAPK2-Hsp27.
Author: Lin, Shih-Pei|Lee, Yi-Ting|Wang, Jir-You|Miller, Stephanie A|Chiou, Shih-Hwa|Hung, Mien-Chie|Hung, Shih-Chieh
PMID: 23185379
Journal: Asian Pac J Cancer Prev. 2012;13(10):5291-8.
Title: Beta-asarone induces LoVo colon cancer cell apoptosis by up-regulation of caspases through a mitochondrial pathway in vitro and in vivo.
Author: Zou, Xi|Liu, Shen-Lin|Zhou, Jin-Yong|Wu, Jian|Ling, Bo-Fan|Wang, Rui-Ping
PMID: 23244151
Journal: Molecules. 2012 Dec 28;18(1):418-29.
Title: (3S)-1,2,3,4-Tetrahydro-beta-carboline-3-carboxylic acid from Cichorium endivia. L induces apoptosis of human colorectal cancer HCT-8 cells.
Author: Wang, Fu-Xin|Deng, An-Jun|Li, Ming|Wei, Jin-Feng|Qin, Hai-Lin|Wang, Ai-Ping
PMID: 23275050
Journal: Phytother Res. 2013 Mar;27(3):422-30.
Title: Curcumin inhibits proliferation and induces apoptosis of human colorectal cancer cells by activating the mitochondria apoptotic pathway.
Author: Guo, Li-da|Chen, Xue-Jie|Hu, Yu-Hong|Yu, Zhi-Jun|Wang, Duo|Liu, Jing-Ze
PMID: 22628241
Journal: Cancer Lett. 2013 Jan 28;328(2):325-34.
Title: The beta6-integrin-ERK/MAP kinase pathway contributes to chemo resistance in colon cancer.
Author: Liu, Song|Wang, Jian|Niu, Weibo|Liu, Enyu|Wang, Jiayong|Peng, Cheng|Lin, Pengfei|Wang, Ben|Khan, Abdul Qadir|Gao, Huijie|Liang, Benjia|Shahbaz, Muhammad|Niu, Jun
PMID: 23073477
Journal: Oncol Lett. 2013 Jan;5(1):321-327.
Title: Predictive markers for the response to 5-fluorouracil therapy in cancer cells: Constant-field gel electrophoresis as a tool for prediction of response to 5-fluorouracil-based chemotherapy.
Author: Saleh, E M|El-Awady, R A|Anis, N
PMID: 23255942
Journal: J Med Food. 2013 Jan;16(1):9-19.
Title: Bamboo salt has in vitro anticancer activity in HCT-116 cells and exerts anti-metastatic effects in vivo.
Author: Zhao, Xin|Kim, So-Young|Park, Kun-Young
PMID: 23256441
Journal: J Pharmacol Sci. 2013;121(1):17-24. Epub 2012 Dec 26.
Title: Tautomycetin induces apoptosis by inactivating Akt through a PP1-independent signaling pathway in human breast cancer cells.
Author: Niu, Mingshan|Sun, Yan|Liu, Xuejiao|Tang, Li|Qiu, Rongguo
PMID: 23269238
Journal: J Zhejiang Univ Sci B. 2013 Jan;14(1):47-57.
Title: Association of CASP9, CASP10 gene polymorphisms and tea drinking with colorectal cancer risk in the Han Chinese population.
Author: Liu, He|Jiang, Xia|Zhang, Ming-wu|Pan, Yi-feng|Yu, Yun-xian|Zhang, Shan-chun|Ma, Xin-yuan|Li, Qi-long|Chen, Kun
PMID: 23303631
Journal: World J Surg Oncol. 2013 Jan 24;11:16.
Title: Increase of cyclooxygenase-2 inhibition with celecoxib combined with 5-FU enhances tumor cell apoptosis and antitumor efficacy in a subcutaneous implantation tumor model of human colon cancer.
Author: Zhang, De-Qing|Guo, Qiang|Zhu, Jian-Hong|Chen, Wei-Chang
PMID: 23347845
Journal: Cancer Biol Ther. 2013 May;14(5):436-49.
Title: Identification of novel compounds that enhance colon cancer cell sensitivity to inflammatory apoptotic ligands.
Author: Chopra, Avijeet S|Kuratnik, Anton|Scocchera, Eric W|Wright, Dennis L|Giardina, Charles
PMID: 23377828
Journal: PLoS One. 2013;8(2):e55993.
Title: Intravenous administration of manuka honey inhibits tumor growth and improves host survival when used in combination with chemotherapy in a melanoma mouse model.
Author: Fernandez-Cabezudo, Maria J|El-Kharrag, Rkia|Torab, Fawaz|Bashir, Ghada|George, Junu A|El-Taji, Hakam|al-Ramadi, Basel K
PMID: 23409104
Journal: Food Chem. 2013 Jun 1;138(2-3):1521-30.
Title: Vitexin-2-O-xyloside, raphasatin and (-)-epigallocatechin-3-gallate synergistically affect cell growth and apoptosis of colon cancer cells.
Author: Papi, Alessio|Farabegoli, Fulvia|Iori, Renato|Orlandi, Marina|De Nicola, Gina R|Bagatta, Manuela|Angelino, Donato|Gennari, Lorenzo|Ninfali, Paolino
PMID: 23411276
Journal: PLoS One. 2013;8(2):e56369.
Title: Pramanicin analog induces apoptosis in human colon cancer cells: critical roles for Bcl-2, Bim, and p38 MAPK signaling.
Author: Bodur, Cagri|Kutuk, Ozgur|Karsli-Uzunbas, Gizem|Isimjan, Tayirjan T|Harrison, Paul|Basaga, Huveyda
PMID: 23441183
Journal: Phytomedicine. 2013 Apr 15;20(6):528-36.
Title: Cytotoxicity and modes of action of four naturally occuring benzophenones: 2,2',5,6'-tetrahydroxybenzophenone, guttiferone E, isogarcinol and isoxanthochymol.
Author: Kuete, Victor|Tchakam, Patricia D|Wiench, Benjamin|Ngameni, Bathelemy|Wabo, Hippolyte K|Tala, Michel F|Moungang, Marlyse L|Ngadjui, Bonaventure T|Murayama, Tetsuya|Efferth, Thomas
PMID: 23507522
Journal: Cell Death Dis. 2013 Mar 28;4:e563.
Title: Netrin-1 protects hypoxia-induced mitochondrial apoptosis through HSP27 expression via DCC- and integrin alpha6beta4-dependent Akt, GSK-3beta, and HSF-1 in mesenchymal stem cells.
Author: Son, T W|Yun, S P|Yong, M S|Seo, B N|Ryu, J M|Youn, H Y|Oh, Y M|Han, H J
PMID: 23538444
Journal: J Physiol Pharmacol. 2013 Feb;64(1):115-23.
Title: Evaluation of apoptotic activity of new condensed pyrazole derivatives.
Author: Toton, E|Ignatowicz, E|Bernard, M K|Kujawski, J|Rybczynska, M
PMID: 23568979
Journal: Med Oncol. 2013;30(3):565.
Title: Association between main Caspase gene polymorphisms and the susceptibility and prognosis of colorectal cancer.
Author: Wu, Zhiwei|Li, Ye|Li, Shuying|Zhu, Lin|Li, Guangxiao|Yu, Zhifu|Zhao, Xiaojuan|Ge, Jie|Cui, Binbin|Dong, Xinshu|Tian, Suli|Hu, Fulan|Zhao, Yashuang
PMID: 23715747
Journal: Cell Death Dis. 2013 Jun 6;4:e659.
Title: miR-129 promotes apoptosis and enhances chemosensitivity to 5-fluorouracil in colorectal cancer.
Author: Karaayvaz, M|Zhai, H|Ju, J
PMID: 23744359
Journal: Oncol Lett. 2013 May;5(5):1744-1748.
Title: Ilex kudingcha C.J. Tseng (Kudingcha) has in vitro anticancer activities in MCF-7 human breast adenocarcinoma cells and exerts anti-metastatic effects in vivo.
Author: Zhao, Xin|Wang, Qiang|Qian, Yu|Song, Jia-LE
PMID: 23760150
Journal: J Ethnopharmacol. 2013 Aug 26;149(1):245-53.
Title: Cytotoxicity and modes of action of four Cameroonian dietary spices ethno-medically used to treat cancers: Echinops giganteus, Xylopia aethiopica, Imperata cylindrica and Piper capense.
Author: Kuete, Victor|Sandjo, Louis P|Wiench, Benjamin|Efferth, Thomas
PMID: 23827757
Journal: Evid Based Complement Alternat Med. 2013;2013:987612.
Title: HSP90 Inhibitors, Geldanamycin and Radicicol, Enhance Fisetin-Induced Cytotoxicity via Induction of Apoptosis in Human Colonic Cancer Cells.
Author: Wu, Ming-Shun|Lien, Gi-Shih|Shen, Shing-Chuan|Yang, Liang-Yo|Chen, Yen-Chou
PMID: 23840275
Journal: Eur J Pharmacol. 2013 Aug 15;714(1-3):379-87.
Title: PBOX-15 induces apoptosis and improves the efficacy of oxaliplatin in human colorectal cancer cell lines.
Author: Gangemi, Giuseppina|Gazzerro, Patrizia|Fiore, Donatella|Proto, Maria Chiara|Butini, Stefania|Gemma, Sandra|Casagni, Alice|Laezza, Chiara|Vitale, Mario|Ligresti, Alessia|Di Marzo, Vincenzo|Zisterer, Daniela M|Nathwani, Seema|Clive Williams, D|Campiani, Giu
PMID: 23872382
Journal: Cell Death Dis. 2013 Aug 1;4:e750.
Title: A ginseng metabolite, compound K, induces autophagy and apoptosis via generation of reactive oxygen species and activation of JNK in human colon cancer cells.
Author: Kim, A D|Kang, K A|Kim, H S|Kim, D H|Choi, Y H|Lee, S J|Kim, H S|Hyun, J W
PMID: 23907464
Journal: Toxicol Lett. 2013 Oct 24;222(2):139-45.
Title: Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactive oxygen species.
Author: Zhou, Jin|Li, Pu|Xue, Xiaofeng|He, Songbing|Kuang, Yuting|Zhao, Hong|Chen, Shaoji|Zhi, Qiaoming|Guo, Xiaobo
PMID: 23916687
Journal: Int J Mol Sci. 2013 Aug 12;14(8):16600-16.
Title: Cadmium modifies the cell cycle and apoptotic profiles of human breast cancer cells treated with 5-fluorouracil.
Author: Asara, Yolande|Marchal, Juan A|Carrasco, Esther|Boulaiz, Houria|Solinas, Giuliana|Bandiera, Pasquale|Garcia, Maria A|Farace, Cristiano|Montella, Andrea|Madeddu, Roberto
PMID: 23941782
Journal: Food Chem Toxicol. 2013 Oct;60:542-9.
Title: Daidzein causes cytochrome c-mediated apoptosis via the Bcl-2 family in human hepatic cancer cells.
Author: Park, Hyun Jin|Jeon, Young Keul|You, Dong Hun|Nam, Myeong Jin
PMID: 23959101
Journal: Biochimie. 2013 Nov;95(11):2157-67.
Title: Antitumour activity on extrinsic apoptotic targets of the triterpenoid maslinic acid in p53-deficient Caco-2 adenocarcinoma cells.
Author: Reyes-Zurita, Fernando J|Rufino-Palomares, Eva E|Medina, Pedro P|Leticia Garcia-Salguero, E|Peragon, Juan|Cascante, Marta|Lupianez, Jose A
PMID: 23973282
Journal: Asian Pac J Cancer Prev. 2013;14(7):4249-54.
Title: Effects of parafibromin expression on the phenotypes and relevant mechanisms in the DLD-1 colon carcinoma cell line.
Author: Zhao, Shuang|Sun, Hong-Zhi|Zhu, Shi-Tu|Lu, Hang|Niu, Zhe-Feng|Guo, Wen-Feng|Takano, Yasuo|Zheng, Hua-Chuan
PMID: 23991985
Journal: Mol Cells. 2013 Sep;36(3):219-26.
Title: Midazolam induces cellular apoptosis in human cancer cells and inhibits tumor growth in xenograft mice.
Author: Mishra, Siddhartha Kumar|Kang, Ju-Hee|Lee, Chang Woo|Oh, Seung Hyun|Ryu, Jun Sun|Bae, Yun Soo|Kim, Hwan Mook
PMID: 24008365
Journal: Anticancer Drugs. 2013 Nov;24(10):1058-68.
Title: Isolation and chemopreventive evaluation of novel naphthoquinone compounds from Alkanna tinctoria.
Author: Tung, Nguyen Huu|Du, Guang-Jian|Yuan, Chun-Su|Shoyama, Yukihiro|Wang, Chong-Zhi
PMID: 24025561
Journal: Biotechnol Lett. 2013 Dec;35(12):2031-8.
Title: Plant-derived mAbs have effective anti-cancer activities by increasing ganglioside expression in colon cancers.
Author: Ryu, Jae-Sung|Lee, Ju-Taek|Lim, Malg-Um|Hwang, Mi-Ran|Hwang, Kyung-A|Cho, Young-Ho|Lee, Jeong-Hwan|Ko, Kisung|Choo, Young-Kug
PMID: 24078119
Journal: Oncol Lett. 2013 Sep;6(3):699-704.
Title: Effects of matrine on the proliferation of HT29 human colon cancer cells and its antitumor mechanism.
Author: Chang, Cheng|Liu, Shao-Ping|Fang, Chun-Hua|He, Ren-Sheng|Wang, Zhen|Zhu, You-Qing|Jiang, Shao-Wei
PMID: 24137393
Journal: Acta Pharmacol Sin. 2013 Dec;34(12):1535-44.
Title: A new bisphosphonate derivative, CP, induces gastric cancer cell apoptosis via activation of the ERK1/2 signaling pathway.
Author: Wang, Hai-jun|Liu, Yu|Fan, Li-qiao|Han, Cai-li|Jiang, Ye|Cheng, Shu-jie|Li, Yong
PMID: 24241351
Journal: PLoS One. 2013 Nov 26;8(11):e82478.
Title: Galectin-3 silencing inhibits epirubicin-induced ATP binding cassette transporters and activates the mitochondrial apoptosis pathway via beta-catenin/GSK-3beta modulation in colorectal carcinoma.
Author: Lee, Yung-Kuo|Lin, Tsung-Hsien|Chang, Chuan-Fa|Lo, Yu-Li
PMID: 24303084
Journal: J Nat Prod. 2013 Dec 27;76(12):2195-202.
Title: Hinokitiol inhibits cell growth through induction of S-phase arrest and apoptosis in human colon cancer cells and suppresses tumor growth in a mouse xenograft experiment.
Author: Lee, Youn-Sun|Choi, Kyeong-Mi|Kim, Wonkyun|Jeon, Young-Soo|Lee, Yong-Moon|Hong, Jin-Tae|Yun, Yeo-Pyo|Yoo, Hwan-Soo
PMID: 24308647
Journal: Pharmacol Rep. 2013;65(5):1366-74.
Title: Inhibition of Wnt/beta-catenin signaling mediates ursolic acid-induced apoptosis in PC-3 prostate cancer cells.
Author: Park, Ji-Hyuk|Kwon, Hee-Young|Sohn, Eun Jung|Kim, Kyung A|Kim, Bonglee|Jeong, Soo-Jin|Song, Jun Ho|Koo, Jin Suk|Kim, Sung-Hoon
PMID: 24399733
Journal: J Environ Pathol Toxicol Oncol. 2013;32(4):275-88.
Title: Fermented Pu-erh tea increases in vitro anticancer activities in HT-29 cells and has antiangiogenetic effects on HUVECs.
Author: Zhao, Xin|Song, Jia-Le|Kim, Jong-Deog|Lee, Jong-Suk|Park, Kun-Young
PMID: 24579782
Journal: Mol Carcinog. 2014 Feb;53 Suppl 1:E119-29.
Title: N-acetyl-L-cysteine enhances fisetin-induced cytotoxicity via induction of ROS-independent apoptosis in human colonic cancer cells.
Author: Wu, Ming-Shun|Lien, Gi-Shih|Shen, Shing-Chuan|Yang, Liang-Yo|Chen, Yen-Chou
PMID: 24019108
Journal: Cell Biol Int. 2014 Mar;38(3):343-54.
Title: DMPPQA, a novel angiogenesis inhibitor, induces apoptosis in human colon cancer HCT-116 cells and HUVECs.
Author: Ren, Jie|Jiang, Hefei|Zhao, Juan|Xin, Wenqun|Xu, Yuanyuan|Chen, Xin|Hu, Kun
PMID: 24293112
Journal: Genes Nutr. 2014 Jan;9(1):359.
Title: The fermented non-digestible fraction of common bean (Phaseolus vulgaris L.) triggers cell cycle arrest and apoptosis in human colon adenocarcinoma cells.
Author: Cruz-Bravo, R K|Guevara-Gonzalez, R G|Ramos-Gomez, M|Oomah, B D|Wiersma, P|Campos-Vega, R|Loarca-Pina, G
PMID: 24293398
Journal: Oncol Lett. 2014 Feb;7(2):493-498.
Title: Inhibitory effects of Dendrobium candidum Wall ex Lindl. on azoxymethane- and dextran sulfate sodium-induced colon carcinogenesis in C57BL/6 mice.
Author: Wang, Qiang|Sun, Peng|Li, Guijie|Zhu, Kai|Wang, Cun|Zhao, Xin
PMID: 24396476
Journal: Int J Oncol. 2014 Apr;44(4):1309-15.
Title: Carnosol induces apoptosis through generation of ROS and inactivation of STAT3 signaling in human colon cancer HCT116 cells.
Author: Park, Ki-Woong|Kundu, Juthika|Chae, In-Gyeong|Kim, Do-Hee|Yu, Mi-Hee|Kundu, Joydeb Kumar|Chun, Kyung-Soo
PMID: 24481553
Journal: Tumour Biol. 2014 Jun;35(6):5307-14.
Title: Dihydroartemisinin induces apoptosis in colorectal cancer cells through the mitochondria-dependent pathway.
Author: Lu, Min|Sun, Luhaoran|Zhou, Jin|Yang, Jing
PMID: 24519064
Journal: Int J Mol Sci. 2014 Feb 17;15(2):2722-37.
Title: Mechanisms underlying apoptosis-inducing effects of Kaempferol in HT-29 human colon cancer cells.
Author: Lee, Hyun Sook|Cho, Han Jin|Yu, Rina|Lee, Ki Won|Chun, Hyang Sook|Park, Jung Han Yoon
PMID: 24549175
Journal: Oncol Rep. 2014 Apr;31(4):1788-94.
Title: Tangeretin, a citrus polymethoxyflavonoid, induces apoptosis of human gastric cancer AGS cells through extrinsic and intrinsic signaling pathways.
Author: Dong, Yang|Cao, Aili|Shi, Jianrong|Yin, Peihao|Wang, Li|Ji, Guang|Xie, Jianqun|Wu, Dazheng
PMID: 24573532
Journal: Eur J Med Chem. 2014 Apr 22;77:323-33.
Title: Induction of intrinsic apoptosis pathway in colon cancer HCT-116 cells by novel 2-substituted-5,6,7,8-tetrahydronaphthalene derivatives.
Author: Gamal-Eldeen, Amira M|Hamdy, Nehal A|Abdel-Aziz, Hatem A|El-Hussieny, Enas A|Fakhr, Issa M I
PMID: 24657569
Journal: Cell Physiol Biochem. 2014;33(4):933-44.
Title: A novel small-molecule YLT205 induces apoptosis in human colorectal cells via mitochondrial apoptosis pathway in vitro and inhibits tumor growth in vivo.
Author: Zhu, Yongxia|Xia, Yong|Ye, Tinghong|Shi, Xuanhong|Song, Xuejiao|Liu, Li|Zeng, Jun|Wang, Ningyu|Luo, Yong|Han, Yuanping|Yu, Luoting
PMID: 24713812
Journal: World J Gastroenterol. 2014 Apr 14;20(14):4001-10.
Title: Epithelial membrane protein 1 negatively regulates cell growth and metastasis in colorectal carcinoma.
Author: Sun, Guo-Gui|Wang, Ya-Di|Cui, Da-Wei|Cheng, Yun-Jie|Hu, Wan-Ning
PMID: 24744589
Journal: Chem Biol Drug Des. 2014 Jul;84(1):36-43.
Title: Antibody against N-terminal domain of phospholipid scramblase 1 induces apoptosis in colorectal cancer cells through the intrinsic apoptotic pathway.
Author: Chen, Chun-Yu|Chen, Jinn-Shiun|Chou, Yeh-Pin|Kuo, Yung-Bin|Fan, Chung-Wei|Chan, Err-Cheng
PMID: 24766818
Journal: Oncol Rep. 2014 Jul;32(1):302-8.
Title: beta1 integrin modulates tumor growth and apoptosis of human colorectal cancer.
Author: Song, Jia|Zhang, Jixiang|Wang, Jing|Cao, Zhuo|Wang, Jun|Guo, Xufeng|Dong, Weiguo
PMID: 24807392
Journal: Oncol Rep. 2014 Aug;32(2):821-8.
Title: Thymoquinone induces apoptosis in human colon cancer HCT116 cells through inactivation of STAT3 by blocking JAK2- and Srcmediated phosphorylation of EGF receptor tyrosine kinase.
Author: Kundu, Juthika|Choi, Bu Young|Jeong, Chul-Ho|Kundu, Joydeb Kumar|Chun, Kyung-Soo
PMID: 24890449
Journal: J Cell Biochem. 2014 Nov;115(11):1888-99.
Title: Expression of survivin and p53 modulates honokiol-induced apoptosis in colorectal cancer cells.
Author: Lai, Ying-Jiun|Lin, Chien-I|Wang, Chia-Lin|Chao, Jui-I
PMID: 24905183
Journal: J Dig Dis. 2014 Sep;15(9):491-500.
Title: Silencing of JMJD2B induces cell apoptosis via mitochondria-mediated and death receptor-mediated pathway activation in colorectal cancer.
Author: Sun, Bei Bei|Fu, Lin Na|Wang, Yun Qian|Gao, Qin Yan|Xu, Jie|Cao, Zhi Jun|Chen, Ying Xuan|Fang, Jing Yuan
PMID: 24957706
Journal: PLoS One. 2014 Jun 24;9(6):e99729.
Title: Activation of JNK contributes to evodiamine-induced apoptosis and G2/M arrest in human colorectal carcinoma cells: a structure-activity study of evodiamine.
Author: Chien, Chih-Chiang|Wu, Ming-Shun|Shen, Shing-Chuan|Ko, Ching-Huai|Chen, Chih-Hung|Yang, Ling-Ling|Chen, Yen-Chou
PMID: 24959718
Journal: Oncol Rep. 2014 Sep;32(3):1124-32.
Title: S-allylmercaptocysteine promotes MAPK inhibitor-induced apoptosis by activating the TGF-beta signaling pathway in cancer cells.
Author: Tong, Dandan|Qu, Hui|Meng, Xiangning|Jiang, Yang|Liu, Duanyang|Ye, Shengqian|Chen, He|Jin, Yan|Fu, Songbin|Geng, Jingshu
PMID: 24970681
Journal: Oncol Lett. 2014 Aug;8(2):699-704.
Title: 5-Fluorouracil-induced apoptosis in colorectal cancer cells is caspase-9-dependent and mediated by activation of protein kinase C-delta
Author: Mhaidat, Nizar M|Bouklihacene, Mohammed|Thorne, Rick F
PMID: 25013487
Journal: Int J Clin Exp Pathol. 2014 May 15;7(6):3312-7. eCollection 2014.
Title: Phosphorylation status of Akt and caspase-9 in gastric and colorectal carcinomas.
Author: Sangawa, Akiko|Shintani, Michiko|Yamao, Naoki|Kamoshida, Shingo
PMID: 25031754
Journal: Free Radic Res. 2014 Nov;48(11):1311-21.
Title: Generation of ROS by CAY10598 leads to inactivation of STAT3 signaling and induction of apoptosis in human colon cancer HCT116 cells.
Author: Chae, I G|Kim, D-H|Kundu, J|Jeong, C-H|Kundu, J K|Chun, K-S
PMID: 25096910
Journal: PLoS One. 2014 Aug 19;9(8):e105405.
Title: Combination effect of epigenetic regulation and ionizing radiation in colorectal cancer cells.
Author: Kim, Joong-Gook|Bae, Jin-Han|Kim, Jin-Ah|Heo, Kyu|Yang, Kwangmo|Yi, Joo Mi
PMID: 25136811
Journal: Cancer Lett. 2014 Dec 28;355(2):297-309.
Title: SKLB316, a novel small-molecule inhibitor of cell-cycle progression, induces G2/M phase arrest and apoptosis in vitro and inhibits tumor growth in vivo.
Author: Xia, Yong|Lei, Qian|Zhu, Yongxia|Ye, Tinghong|Wang, Ningyu|Li, Guobo|Shi, Xuanhong|Liu, Yantong|Shao, Bin|Yin, Tao|Zhao, Lifeng|Wu, Wenshuang|Song, Xuejiao|Xiong, Ying|Wei, Yuquan|Yu, Luoting
PMID: 25301449
Journal: Oncol Rep. 2014 Dec;32(6):2845-53.
Title: Paeonol exerts an anticancer effect on human colorectal cancer cells through inhibition of PGE(2) synthesis and COX-2 expression.
Author: Li, Ming|Tan, Shi-Yun|Wang, Xiao-Fan
PMID: 25322760
Journal: Nutr Res Pract. 2014 Oct;8(5):487-93.
Title: D. candidum has in vitro anticancer effects in HCT-116 cancer cells and exerts in vivo anti-metastatic effects in mice.
Author: Zhao, Xin|Sun, Peng|Qian, Yu|Suo, Huayi
PMID: 25324926
Journal: BMC Complement Altern Med. 2014 Oct 24;14:412.
Title: Hederagenin from the leaves of ivy (Hedera helix L.) induces apoptosis in human LoVo colon cells through the mitochondrial pathway.
Author: Liu, Bao-Xin-Zi|Zhou, Jin-Yong|Li, Yu|Zou, Xi|Wu, Jian|Gu, Jun-Fei|Yuan, Jia-Rui|Zhao, Bing-Jie|Feng, Liang|Jia, Xiao-Bin|Wang, Rui-Ping
PMID: 25342273
Journal: Oncol Lett. 2014 Dec;8(6):2581-2586.
Title: Smac/DIABLO expression in human gastrointestinal carcinoma: Association with clinicopathological parameters and survivin expression.
Author: Shintani, Michiko|Sangawa, Akiko|Yamao, Naoki|Kamoshida, Shingo
PMID: 25364431
Journal: ScientificWorldJournal. 2014;2014:129697.
Title: Achyranthes aspera root extracts induce human colon cancer cell (COLO-205) death by triggering the mitochondrial apoptosis pathway and S phase cell cycle arrest.
Author: Arora, Shagun|Tandon, Simran
PMID: 25401123
Journal: In Vitro Cell Dev Biol Anim. 2015 Jan;51(1):92-101.
Title: [10]-Gingerol induces mitochondrial apoptosis through activation of MAPK pathway in HCT116 human colon cancer cells.
Author: Ryu, Min Ju|Chung, Ha Sook
PMID: 25148824
Journal: J Med Food. 2015 Mar;18(3):332-6.
Title: Khz (fusion product of Ganoderma lucidum and Polyporus umbellatus mycelia) induces apoptosis in human colon carcinoma HCT116 cells, accompanied by an increase in reactive oxygen species, activation of caspase 3, and increased intracellular Ca(2)(+).
Author: Kim, Tae Hwan|Kim, Ju Sung|Kim, Zoo Haye|Huang, Ren Bin|Chae, Young Lye|Wang, Ren Sheng
PMID: 25489715
Journal: Arch Toxicol. 2015 Oct;89(10):1829-46.
Title: Lipoic acid induces p53-independent cell death in colorectal cancer cells and potentiates the cytotoxicity of 5-fluorouracil.
Author: Dorsam, Bastian|Goder, Anja|Seiwert, Nina|Kaina, Bernd|Fahrer, Jorg
PMID: 25526924
Journal: Homeopathy. 2015 Jan;104(1):36-47.
Title: DNA fragmentation and cell cycle arrest: a hallmark of apoptosis induced by Ruta graveolens in human colon cancer cells.
Author: Arora, Shagun|Tandon, Simran
PMID: 25576270
Journal: Methods Mol Biol. 2015;1265:85-101.
Title: Mitochondriotropic nanoemulsified genistein-loaded vehicles for cancer therapy.
Author: Pham, Jimmy|Grundmann, Oliver|Elbayoumi, Tamer
PMID: 25634269
Journal: Sci Rep. 2015 Mar 13;5:9097.
Title: Apoptotic effect of novel Schiff based CdCl(2)(C(1)(4)H(2)(1)N(3)O(2)) complex is mediated via activation of the mitochondrial pathway in colon cancer cells.
Author: Hajrezaie, Maryam|Paydar, Mohammadjavad|Looi, Chung Yeng|Moghadamtousi, Soheil Zorofchian|Hassandarvish, Pouya|Salga, Muhammad Saleh|Karimian, Hamed|Shams, Keivan|Zahedifard, Maryam|Majid, Nazia Abdul|Ali, Hapipah Mohd|Abdulla, Mahmood Ameen
PMID: 25764970
Journal: Mol Med Rep. 2015 Jul;12(1):1189-96.
Title: Nitrogen permease regulator-like 2 enhances sensitivity to oxaliplatin in colon cancer cells.
Author: Liu, Ming-Na|Liu, Ai-Yun|Du, Ya-Ju|Pei, Feng-Hua|Wang, Xin-Hong|Chen, Jing|Liu, Dan|Liu, Bing-Rong
PMID: 25777765
Journal: Cell Physiol Biochem. 2015;35(5):1821-30.
Title: Cinnamaldehyde derivative (CB-PIC) sensitizes chemo-resistant cancer cells to drug-induced apoptosis via suppression of MDR1 and its upstream STAT3 and AKT signalling.
Author: Yun, Miyong|Lee, Duckgue|Park, Moon-Nyeo|Kim, Eun-Ok|Sohn, Eun Jung|Kwon, Byung-Mog|Kim, Sung-Hoon
PMID: 25833196
Journal: PLoS One. 2015 Apr 10;10(4):e0122288.
Title: The chemopotential effect of Annona muricata leaves against azoxymethane-induced colonic aberrant crypt foci in rats and the apoptotic effect of Acetogenin Annomuricin E in HT-29 cells: a bioassay-guided approach.
Author: Zorofchian Moghadamtousi, Soheil|Rouhollahi, Elham|Karimian, Hamed|Fadaeinasab, Mehran|Firoozinia, Mohammad|Ameen Abdulla, Mahmood|Abdul Kadir, Habsah
PMID: 25860620
Journal: J Hematol Oncol. 2015 Mar 15;8:26.
Title: Aloperine executes antitumor effects against multiple myeloma through dual apoptotic mechanisms.
Author: Wang, He|Yang, Shu|Zhou, Hong|Sun, Mingna|Du, Lingran|Wei, Minyan|Luo, Meixia|Huang, Jingzhu|Deng, Hongzhu|Feng, Yinghong|Huang, Jun|Zhou, Yi
PMID: 25886453
Journal: Nutr J. 2015 Apr 1;14:31.
Title: Combined ginger extract & Gelam honey modulate Ras/ERK and PI3K/AKT pathway genes in colon cancer HT29 cells.
Author: Tahir, Analhuda Abdullah|Sani, Nur Fathiah Abdul|Murad, Noor Azian|Makpol, Suzana|Ngah, Wan Zurinah Wan|Yusof, Yasmin Anum Mohd
PMID: 25889965
Journal: Arch Iran Med. 2015 May;18(5):284-95.
Title: Mushroom Extracts Induce Human Colon Cancer Cell (COLO-205) Death by Triggering the Mitochondrial Apoptosis Pathway and Go/G1-Phase Cell Cycle Arrest.
Author: Arora, Shagun|Tandon, Simran
PMID: 25959910
Journal: Biomed Pharmacother. 2015 Apr;71:119-27.
Title: Diorganotin (IV) complexes with 4-nitro-N-phthaloyl-glycine: Synthesis, characterization, antitumor activity and DNA-binding studies.
Author: Yan, Chaoqun|Zhang, Jiali|Liang, Taigang|Li, Qingshan
PMID: 25960226
Journal: Int J Clin Exp Pathol. 2015 Feb 1;8(2):1402-10. eCollection 2015.
Title: Inositol hexaphosphate suppresses growth and induces apoptosis in HT-29 colorectal cancer cells in culture: PI3K/Akt pathway as a potential target.
Author: Liu, Guiyuan|Song, Yang|Cui, Lianhua|Wen, Zhaoxia|Lu, Xiaoqing
PMID: 25973024
Journal: Biomed Pharmacother. 2015 May;72:125-34.
Title: Oridonin triggers apoptosis in colorectal carcinoma cells and suppression of microRNA-32 expression augments oridonin-mediated apoptotic effects.
Author: Yang, Jie|Jiang, Hai|Wang, Chunyu|Yang, Bo|Zhao, Lijun|Hu, Dongling|Qiu, Guihua|Dong, Xiaolin|Xiao, Bin
PMID: 26054686
Journal: Oxid Med Cell Longev. 2015;2015:154164.
Title: Impact of Procyanidins from Different Berries on Caspase 8 Activation in Colon Cancer.
Author: Minker, Carole|Duban, Livine|Karas, Daniel|Jarvinen, Paivi|Lobstein, Annelise|Muller, Christian D
PMID: 26180579
Journal: Acta Pharmacol Sin. 2015 Sep;36(9):1074-84.
Title: New benzimidazole acridine derivative induces human colon cancer cell apoptosis in vitro via the ROS-JNK signaling pathway.
Author: Chen, Kang|Chu, Bi-zhu|Liu, Feng|Li, Bin|Gao, Chun-mei|Li, Lu-lu|Sun, Qin-sheng|Shen, Zhi-fa|Jiang, Yu-yang
PMID: 26235743
Journal: Eur J Med Chem. 2015 Sep 18;102:93-105.
Title: Synthesis and biological evaluation of a novel betulinic acid derivative as an inducer of apoptosis in human colon carcinoma cells (HT-29).
Author: Chakraborty, Biswajit|Dutta, Debasmita|Mukherjee, Sanjukta|Das, Supriya|Maiti, Nakul C|Das, Padma|Chowdhury, Chinmay
PMID: 26248310
Journal: Int J Mol Sci. 2015 Aug 17;16(8):19401-18.
Title: Methyl Sartortuoate Inhibits Colon Cancer Cell Growth by Inducing Apoptosis and G2/M-Phase Arrest.
Author: Lan, Qiusheng|Li, Shoufeng|Lai, Wei|Xu, Heyang|Zhang, Yang|Zeng, Yujie|Lan, Wenjian|Chu, Zhonghua
PMID: 26287184
Journal: Arch Pharm (Weinheim). 2015 Oct;348(10):730-42.
Title: Synthesis of Tolmetin Hydrazide-Hydrazones and Discovery of a Potent Apoptosis Inducer in Colon Cancer Cells.
Author: Kucukguzel, S Guniz|Koc, Derya|Cikla-Suzgun, Pelin|Ozsavci, Derya|Bingol-Ozakpinar, Ozlem|Mega-Tiber, Pinar|Orun, Oya|Erzincan, Pinar|Sag-Erdem, Safiye|Sahin, Fikrettin
PMID: 26287512
Journal: Colloids Surf B Biointerfaces. 2015 Nov 1;135:793-801.
Title: Novel self-micellizing anticancer lipid nanoparticles induce cell death of colorectal cancer cells.
Author: Sundaramoorthy, Pasupathi|Baskaran, Rengarajan|Mishra, Siddhartha Kumar|Jeong, Keun-Yeong|Oh, Seung Hyun|Kyu Yoo, Bong|Kim, Hwan Mook
PMID: 26342325
Journal: PLoS One. 2015 Sep 14;10(9):e0137888.
Title: Gypenosides Synergistically Enhances the Anti-Tumor Effect of 5-Fluorouracil on Colorectal Cancer In Vitro and In Vivo: A Role for Oxidative Stress-Mediated DNA Damage and p53 Activation.
Author: Kong, Lulu|Wang, Xiaobing|Zhang, Kun|Yuan, Wenjuan|Yang, Qiwen|Fan, Jianping|Wang, Pan|Liu, Quanhong
PMID: 26368019
Journal: Int J Oncol. 2015 Nov;47(5):1749-58.
Title: Colon cancer chemopreventive effects of baicalein, an active enteric microbiome metabolite from baicalin.
Author: Wang, Chong-Zhi|Zhang, Chun-Feng|Chen, Lina|Anderson, Samantha|Lu, Fang|Yuan, Chun-Su
PMID: 26398706
Journal: EXCLI J. 2015 Feb 24;14:294-306.
Title: A sulfated polysaccharide of Ecklonia cava inhibits the growth of colon cancer cells by inducing apoptosis.
Author: Ahn, Ginnae|Lee, WonWon|Kim, Kil-Nam|Lee, Ji-Hyeok|Heo, Soo-Jin|Kang, Nalae|Lee, Seung-Hong|Ahn, Chang-Bum|Jeon, You-Jin
PMID: 26417363
Journal: Int J Clin Exp Pathol. 2015 Aug 1;8(8):9097-104. eCollection 2015.
Title: The silence of p66(Shc) in HCT8 cells inhibits the viability via PI3K/AKT/Mdm-2/p53 signaling pathway.
Author: Zhang, Ling|Zhu, Shengtao|Shi, Xuesen|Sha, Weihong
PMID: 26464652
Journal: Exp Ther Med. 2015 Oct;10(4):1602-1608.
Title: Scutellaria barbata D. Don inhibits growth and induces apoptosis by suppressing IL-6-inducible STAT3 pathway activation in human colorectal cancer cells.
Author: Jiang, Qiqin|Li, Qiongyu|Chen, Hongwei|Shen, Aling|Cai, Qiaoyan|Lin, Jiumao|Peng, Jun
PMID: 26622533
Journal: Oncol Lett. 2015 Dec;10(6):3682-3688.
Title: Functional mechanism of the enhancement of 5-fluorouracil sensitivity by TUSC4 in colon cancer cells.
Author: Liu, Ming-Na|Liu, Ai-Yun|Pei, Feng-Hua|Ma, Xiao|Fan, Yu-Jing|DU, Ya-Ju|Liu, Bing-Rong
PMID: 26788191
Journal: Mol Carcinog. 2016 Aug;55(8):1262-74.
Title: Nexrutine inhibits azoxymethane-induced colonic aberrant crypt formation in rat colon and induced apoptotic cell death in colon adenocarcinoma cells.
Author: Alam, Shamshad|Pal, Anu|Kumar, Rahul|Mir, Snober S|Ansari, Kausar M
PMID: 26259065
Journal: Apoptosis. 2016 Mar;21(3):298-311.
Title: Depletion of histone N-terminal-acetyltransferase Naa40 induces p53-independent apoptosis in colorectal cancer cells via the mitochondrial pathway.
Author: Pavlou, Demetria|Kirmizis, Antonis
PMID: 26666750
Journal: Food Funct. 2016 Feb;7(2):843-54.
Title: A serine protease extracted from Trichosanthes kirilowii induces apoptosis via the PI3K/AKT-mediated mitochondrial pathway in human colorectal adenocarcinoma cells.
Author: Song, Li|Chang, Jiao|Li, Zhuoyu
PMID: 26673746
Journal: J Enzyme Inhib Med Chem. 2016 Dec;31(6):1286-99.
Title: Novel 1,5-diphenyl-6-substituted 1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones induced apoptosis in RKO colon cancer cells.
Author: Malki, Ahmed|Ashour, Hayam M A|Elbayaa, Rasha Y|Issa, Doaa A E|Aziz, Hassan A|Chen, Xiaozhuo
PMID: 26677729
Journal: Planta Med. 2016 Mar;82(4):312-21.
Title: Thymoquinone from Nigella sativa Seeds Promotes the Antitumor Activity of Noncytotoxic Doses of Topotecan in Human Colorectal Cancer Cells in Vitro.
Author: Khalife, Rana|Hodroj, Mohammad Hassan|Fakhoury, Rajaa|Rizk, Sandra
PMID: 26848703
Journal: Mol Med Rep. 2016 Apr;13(4):3525-32.
Title: Growth inhibition effects of ent-11alpha-hydroxy-15-oxo-kaur-16-en-19-oic-acid on colorectal carcinoma cells and colon carcinoma-bearing mice.
Author: Ye, Hua|Wu, Qiong|Guo, Meng|Wu, Kefeng|Lv, Yingnian|Yu, Fengyan|Liu, Yi|Gao, Xiaosheng|Zhu, Yuzhen|Cui, Liao|Liang, Nianci|Yun, Tu|Li, Li|Zheng, Xuebao
PMID: 26935771
Journal: Colloids Surf B Biointerfaces. 2016 Jul 1;143:499-510.
Title: Polyphenol stabilized colloidal gold nanoparticles from Abutilon indicum leaf extract induce apoptosis in HT-29 colon cancer cells.
Author: Mata, Rani|Nakkala, Jayachandra Reddy|Sadras, Sudha Rani
PMID: 27038915
Journal: J BUON. 2016 Jan-Feb;21(1):87-94.
Title: Arctigenin induces apoptosis in colon cancer cells through ROS/p38MAPK pathway.
Author: Li, Qing-chun|Liang, Yun|Tian, Yuan|Hu, Guang-rui
PMID: 27061535
Journal: J Gastrointest Cancer. 2016 Jun;47(2):187-95.
Title: The Herbal Medicine Utrica Dioica Inhibits Proliferation of Colorectal Cancer Cell Line by Inducing Apoptosis and Arrest at the G2/M Phase.
Author: Mohammadi, Ali|Mansoori, Behzad|Aghapour, Mahyar|Baradaran, Pooneh Chokhachi|Shajari, Neda|Davudian, Sadaf|Salehi, Shima|Baradaran, Behzad
PMID: 27090648
Journal: Biomol Ther (Seoul). 2016 May 1;24(3):320-7.
Title: Columbianadin Inhibits Cell Proliferation by Inducing Apoptosis and Necroptosis in HCT116 Colon Cancer Cells.
Author: Kang, Ji In|Hong, Ji-Young|Choi, Jae Sue|Lee, Sang Kook
PMID: 27098859
Journal: Molecules. 2016 Jun 4;21(6). pii: molecules21060730.
Title: Dioscin Induces Apoptosis in Human Cervical Carcinoma HeLa and SiHa Cells through ROS-Mediated DNA Damage and the Mitochondrial Signaling Pathway.
Author: Zhao, Xinwei|Tao, Xufeng|Xu, Lina|Yin, Lianhong|Qi, Yan|Xu, Youwei|Han, Xu|Peng, Jinyong
PMID: 27271587
Journal: Chin J Integr Med. 2016 Jun 29. pii: 10.1007/s11655-016-2597-8.
Title: Tounong Powder () extracts induce G1 cell cycle arrest and apoptosis in LoVo cells.
Author: Fang, Liang-Hua|Liu, Shen-Lin|Wang, Rui-Ping|Hu, Shou-You|Ju, Wen-Zheng|Li, Chang-Yin
PMID: 27358203
Journal: Acta Biomater. 2016 Sep 15;42:220-231.
Title: Engineering of caveolae-specific self-micellizing anticancer lipid nanoparticles to enhance the chemotherapeutic efficacy of oxaliplatin in colorectal cancer cells.
Author: Sundaramoorthy, Pasupathi|Ramasamy, Thiruganesh|Mishra, Siddhartha Kumar|Jeong, Keun-Yeong|Yong, Chul Soon|Kim, Jong Oh|Kim, Hwan Mook
PMID: 27395829
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2016 Jun 20;36(7):921-6.
Title: [Mechanism of colon cancer cell apoptosis induced by telocinobufagin: role of oxidative stress and apoptosis pathway].
Author: Liang, Shun-Tian|Li, Yuan|Li, Xiao-Wu|Wang, Jun-Jiang|Tan, Fu-Xian|Han, Qin-Rui|Li, Lu|Yao, Xue-Qing|Sun, Xue-Gang
PMID: 27435769
Journal: Molecules. 2016 Jul 19;21(7). pii: molecules21070934.
Title: Protocatechualdehyde Induces S-Phase Arrest and Apoptosis by Stimulating the p27(KIP1)-Cyclin A/D1-CDK2 and Mitochondrial Apoptotic Pathways in HT-29 Cells.
Author: Zhong, Shi|Li, You-Gui|Ji, Dong-Feng|Lin, Tian-Bao|Lv, Zhi-Qiang
PMID: 27447597
Journal: BMC Complement Altern Med. 2016 Jul 29;16:256.
Title: Clausenidin induces caspase-dependent apoptosis in colon cancer.
Author: Waziri, Peter M|Abdullah, Rasedee|Yeap, Swee Keong|Omar, Abdul Rahman|Kassim, Nur Kartinee|Malami, Ibrahim|How, Chee Wun|Etti, Imaobong Christopher|Abu, Mary Ladidi
PMID: 27473055
Journal: Front Pharmacol. 2016 Jul 25;7:217.
Title: A Ribonuclease Isolated from Wild Ganoderma Lucidum Suppressed Autophagy and Triggered Apoptosis in Colorectal Cancer Cells.
Author: Dan, Xiuli|Liu, Wenlong|Wong, Jack H|Ng, Tzi B
PMID: 27504094
Journal: Oncotarget. 2016 Sep 13;7(37):60575-60592.
Title: Inhibition of glucosylceramide synthase eliminates the oncogenic function of p53 R273H mutant in the epithelial-mesenchymal transition and induced pluripotency of colon cancer cells.
Author: Hosain, Salman B|Khiste, Sachin K|Uddin, Mohammad B|Vorubindi, Vindya|Ingram, Catherine|Zhang, Sifang|Hill, Ronald A|Gu, Xin|Liu, Yong-Yu
PMID: 27517620
Journal: Sci Rep. 2016 Sep 13;6:32979.
Title: Crocetin exploits p53-induced death domain (PIDD) and FAS-associated death domain (FADD) proteins to induce apoptosis in colorectal cancer.
Author: Ray, Pallab|Guha, Deblina|Chakraborty, Juni|Banerjee, Shuvomoy|Adhikary, Arghya|Chakraborty, Samik|Das, Tanya|Sa, Gaurisankar
PMID: 27622714
Journal: Oncol Lett. 2016 Nov;12(5):3537-3542.
Title: Anticancer effect of icaritin inhibits cell growth of colon cancer through reactive oxygen species, Bcl-2 and cyclin D1/E signaling.
Author: Li, Chaofeng|Peng, Weichao|Song, Xin|Wang, Qian|Wang, Wenyue
PMID: 27900033
Journal: J Tradit Chin Med. 2016 Aug;36(4):514-21.
Title: Diterpenoid Tanshinones, the extract from Danshen (Radix Salviae Miltiorrhizae) induced apoptosis in nine human cancer cell lines.
Author: Shen, Li|Lou, Zhaohuan|Zhang, Guangshun|Xu, Guanhua|Zhang, Guangji
PMID: 28459519
Journal: Integr Med Res. 2016 Dec;5(4):284-292.
Title: Water extract of Galla Rhois with steaming process enhances apoptotic cell death in human colon cancer cells.
Author: Yim, Nam-Hui|Gu, Min Jung|Hwang, Youn-Hwan|Cho, Won-Kyung|Ma, Jin Yeul
PMID: 28462130
Journal: Iran J Biotechnol. 2016 Sep;14(3):177-184.
Title: Anticancer Properties of Chrysin on Colon Cancer Cells, In vitro and In vivo with Modulation of Caspase-3, -9, Bax and Sall4.
Author: Bahadori, Maliheh|Baharara, Javad|Amini, Elaheh
PMID: 28959334
Journal: J Gastrointest Cancer. 2017 Jun;48(2):156-163.
Title: siRNA-Mediated Silencing of HMGA2 Induces Apoptosis and Cell Cycle Arrest in Human Colorectal Carcinoma.
Author: Esmailzadeh, Sahar|Mansoori, Behzad|Mohammadi, Ali|Shanehbandi, Dariush|Baradaran, Behzad
PMID: 27629422
Journal: Oncol Rep. 2017 Feb;37(2):1132-1140.
Title: Apigenin induces both intrinsic and extrinsic pathways of apoptosis in human colon carcinoma HCT-116 cells.
Author: Wang, Bo|Zhao, Xin-Huai
PMID: 27959417
Journal: Eur J Pharmacol. 2017 Feb 5;796:139-148.
Title: MC37, a new mono-carbonyl curcumin analog, induces G2/M cell cycle arrest and mitochondria-mediated apoptosis in human colorectal cancer cells.
Author: Liang, Baoxia|Liu, Ziyi|Cao, Yingnan|Zhu, Cuige|Zuo, Yinglin|Huang, Lei|Wen, Gesi|Shang, Nana|Chen, Yu|Yue, Xin|Du, Jun|Li, Baojian|Zhou, Binhua|Bu, Xianzhang
PMID: 28024945
Journal: BMC Cancer. 2017 Jan 3;17(1):4.
Title: Novel derivative of aminobenzenesulfonamide (3c) induces apoptosis in colorectal cancer cells through ROS generation and inhibits cell migration.
Author: Al-Khayal, Khayal|Alafeefy, Ahmed|Vaali-Mohammed, Mansoor-Ali|Mahmood, Amer|Zubaidi, Ahmed|Al-Obeed, Omar|Khan, Zahid|Abdulla, Maha|Ahmad, Rehan
PMID: 28049506
Journal: Acta Biochim Biophys Sin (Shanghai). 2017 Mar 1;49(3):228-237.
Title: Salubrinal protects against Clostridium difficile toxin B-induced CT26 cell death.
Author: Chen, Shuyi|Sun, Chunli|Gu, Huawei|Wang, Haiying|Li, Shan|Ma, Yi|Wang, Jufang
PMID: 28119311
Journal: Oncol Lett. 2017 Jan;13(1):81-88.
Title: miR-433 reduces cell viability and promotes cell apoptosis by regulating MACC1 in colorectal cancer.
Author: Li, Jiaxin|Mao, Xuping|Wang, Xing|Miao, Ganggang|Li, Jiaxin
PMID: 28123526
Journal: J Agric Food Chem. 2017 Mar 1;65(8):1566-1573.
Title: Novel ent-Kaurane Diterpenoid from Rubus corchorifolius L. f. Inhibits Human Colon Cancer Cell Growth via Inducing Cell Cycle Arrest and Apoptosis.
Author: Chen, Xuexiang|Wu, Xian|Ouyang, Wen|Gu, Min|Gao, Zili|Song, Mingyue|Chen, Yunjiao|Lin, Yanyin|Cao, Yong|Xiao, Hang
PMID: 28169543
Journal: Arch Pharm Res. 2017 May;40(5):579-591.
Title: TEOA, a triterpenoid from Actinidia eriantha, induces autophagy in SW620 cells via endoplasmic reticulum stress and ROS-dependent mitophagy.
Author: Zhang, Dandan|Gao, Cuixia|Li, Ruyi|Zhang, Lin|Tian, Jingkui
PMID: 28211011
Journal: Oncol Lett. 2017 Apr;13(4):2337-2343.
Title: Stevioside induced cytotoxicity in colon cancer cells via reactive oxygen species and mitogen-activated protein kinase signaling pathways-mediated apoptosis.
Author: Ren, Hai-Peng|Yin, Xiao-Yan|Yu, Hai-Ying|Xiao, Hai-Feng
PMID: 28454400
Journal: Biomed Pharmacother. 2017 Jul;91:320-329.
Title: Cisatracurium-induced proliferation impairment and death of colorectal cancer cells, HCT116 is mediated by p53 dependent intrinsic apoptotic pathway in vitro.
Author: Yabasin, Iddrisu Baba|Lu, ZhiLi|Yu, Jia-Chuan|Wen, Qingping
PMID: 28463795
Journal: Nutr Res. 2017 May;41:36-46.
Title: Secretion metabolites of probiotic yeast, Pichia kudriavzevii AS-12, induces apoptosis pathways in human colorectal cancer cell lines.
Author: Saber, Amir|Alipour, Beitollah|Faghfoori, Zeinab|Mousavi Jam, Ali|Yari Khosroushahi, Ahmad
PMID: 28477945
Journal: PLoS One. 2017 May 10;12(5):e0177171.
Title: Tafazzin (TAZ) promotes the tumorigenicity of cervical cancer cells and inhibits apoptosis.
Author: Chen, Mei|Zhang, Yuan|Zheng, Peng-Sheng
PMID: 28489874
Journal: Oncol Lett. 2017 May;13(5):3799-3802.
Title: An active molecule from Pulsatilla chinensis, Pulsatilla saponin A, induces apoptosis and inhibits tumor growth of human colon cancer cells without or with 5-FU.
Author: Xu, Liming|Cheng, Guilian|Lu, Yi|Wang, Shaofeng
PMID: 28529594
Journal: Biomed Pharmacother. 2017 Aug;92:78-85.
Title: Isofraxidin inhibited proliferation and induced apoptosis via blockage of Akt pathway in human colorectal cancer cells.
Author: Shen, Peng|Wang, Hong-Gang|Li, Miao-Miao|Ma, Qian-Yun|Zhou, Chuan-Wen|Pan, Feng|Xie, Rui
PMID: 28531803
Journal: Oncol Lett. 2017 Aug;14(2):2177-2185.
Title: Effects of 17-allylamino-17-demethoxygeldanamycin on the induction of apoptosis and cell cycle arrest in HCT-116 cells.
Author: Zhao, Xuerong|Wang, Jianping|Xiao, Lijun|Xu, Qian|Zhao, Enhong|Zheng, Xin|Zheng, Huachuan|Zhao, Shuang|Ding, Shi
PMID: 28789442
Journal: Int J Oncol. 2017 Oct;51(4):1169-1178.
Title: Luteolin induces apoptotic cell death via antioxidant activity in human colon cancer cells.
Author: Kang, Kyoung Ah|Piao, Mei Jing|Ryu, Yea Seong|Hyun, Yu Jae|Park, Jeong Eon|Shilnikova, Kristina|Zhen, Ao Xuan|Kang, Hee Kyoung|Koh, Young Sang|Jeong, Yong Joo|Hyun, Jin Won
PMID: 28791416
Journal: Eur J Med Chem. 2017 Oct 20;139:250-262.
Title: Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene)thiazolidin-2-ylidene)amino) benzenesulfonamides: Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular modelling studies.
Author: Eldehna, Wagdy M|Abo-Ashour, Mahmoud F|Nocentini, Alessio|Gratteri, Paola|Eissa, Ibrahim H|Fares, Mohamed|Ismael, Omnia E|Ghabbour, Hazem A|Elaasser, Mahmoud M|Abdel-Aziz, Hatem A|Supuran, Claudiu T
PMID: 28802125
Journal: Chin J Nat Med. 2017 Jul;15(7):505-514.
Title: Mesua ferrea stem bark extract induces apoptosis and inhibits metastasis in human colorectal carcinoma HCT 116 cells, through modulation of multiple cell signalling pathways.
Author: Asif, Muhammad|Shafaei, Armaghan|Abdul Majid, Aman Shah|Ezzat, Mohammed Oday|Dahham, Saad S|Ahamed, Mohamed B Khadeer|Oon, Chern Ein|Abdul Majid, Amin Malik Shah
PMID: 28807224
Journal: J Inorg Biochem. 2017 Dec;177:27-38.
Title: In vitro anticancer activity of new gold(III) porphyrin complexes in colon cancer cells.
Author: Dandash, Fatima|Leger, David Yannick|Fidanzi-Dugas, Chloe|Nasri, Soumaya|Bregier, Frederique|Granet, Robert|Karam, Walid|Diab-Assaf, Mona|Sol, Vincent|Liagre, Bertrand
PMID: 28923355
Journal: Front Pharmacol. 2017 Sep 12;8:640.
Title: Morin Inhibits Proliferation of SW480 Colorectal Cancer Cells by Inducing Apoptosis Mediated by Reactive Oxygen Species Formation and Uncoupling of Warburg Effect.
Author: Sithara, Thomas|Arun, K B|Syama, H P|Reshmitha, T R|Nisha, P
PMID: 28955240
Journal: Molecules. 2017 Oct 3;22(10). pii: molecules22101657.
Title: Inositol Hexaphosphate Inhibits Proliferation and Induces Apoptosis of Colon Cancer Cells by Suppressing the AKT/mTOR Signaling Pathway.
Author: Kapral, Malgorzata|Wawszczyk, Joanna|Jesse, Katarzyna|Paul-Samojedny, Monika|Kusmierz, Dariusz|Weglarz, Ludmila
PMID: 28972559
Journal: Acta Biochim Biophys Sin (Shanghai). 2017 Oct 1;49(10):926-934.
Title: Knockdown of SLC39A7 inhibits cell growth and induces apoptosis in human colorectal cancer cells.
Author: Sheng, Nengquan|Yan, Li|You, Weiqiang|Tan, Gewen|Gong, Jianfeng|Chen, Hongqi|Yang, Yi|Hu, Landian|Wang, Zhigang
PMID: 28981607
Journal: Tumour Biol. 2017 Oct;39(10):1010428317720569.
Title: In vitro investigation of the effect of matrix molecules on the behavior of colon cancer cells under the effect of geldanamycin derivative.
Author: Vural, Kamil|Kosova, Funda|Kurt, Feyzan Ozdal|Tuglu, Ibrahim
PMID: 29034805
Journal: Oncol Rep. 2017 Dec;38(6):3439-3446.
Title: Synergism between alpha-mangostin and TRAIL induces apoptosis in squamous cell carcinoma of the oral cavity through the mitochondrial pathway.
Author: Fukuda, Masakatsu|Sakashita, Hide|Hayashi, Hiroyasu|Shiono, Junya|Miyake, Genki|Komine, Yusuke|Taira, Fuyoko|Sakashita, Hideaki
PMID: 29039600
Journal: Exp Ther Med. 2017 Oct;14(4):3533-3540.
Title: Pien Tze Huang induces apoptosis and inhibits proliferation of 5-fluorouracil-resistant colorectal carcinoma cells via increasing miR-22 expression.
Author: Chen, Zhaorong|Shen, Aling|Liu, Liya|Chen, Youqin|Chu, Jianfeng|Cai, Qiaoyan|Qi, Fei|Sferra, Thomas Joseph|Peng, Jun
PMID: 29042944
Journal: PLoS One. 2017 Oct 24;12(10):e0184501.
Title: The preclinical analysis of TW-37 as a potential anti-colorectal cancer cell agent.
Author: Lei, Shun|Ding, Yao|Fu, Yun|Wu, Shuang|Xie, Xiong|Wang, Cancan|Liang, Houjie
PMID: 29065135
Journal: Oncol Lett. 2017 Nov;14(5):5853-5860.
Title: Grape seed proanthocyanidins induce mitochondrial pathway-mediated apoptosis in human colorectal carcinoma cells.
Author: Zhang, Chen|Chen, Weili|Zhang, Xuhao|Zheng, Yanbing|Yu, Fengli|Liu, Yulong|Wang, Yi
PMID: 29113217
Journal: Saudi J Biol Sci. 2017 Dec;24(8):1781-1786.
Title: Establishment of optimal regulatory network of colorectal cancer based on p42.3 protein.
Author: Hao, Yibin|Zhang, Jianhua|Shan, Guoyong|Zhang, Ning|Jin, Wenwen|Nan, Kejun
PMID: 29551923
Journal: Cytotechnology. 2018 Feb;70(1):321-329.
Title: Berbamine suppresses cell viability and induces apoptosis in colorectal cancer via activating p53-dependent apoptotic signaling pathway.
Author: Zhang, Heng|Jiao, Yunping|Shi, Chunyang|Song, Xiao|Chang, Ying|Ren, Yong|Shi, Xiaolin
PMID: 28965196
Journal: Oncol Rep. 2018 Jan;39(1):61-70.
Title: Crosstalk between p38 MAPK and caspase-9 regulates mitochondria-mediated apoptosis induced by tetra-alpha-(4-carboxyphenoxy) phthalocyanine zinc photodynamic therapy in LoVo cells.
Author: Wang, Yu|Xia, Chunhui|Lun, Zhiqiang|Lv, Yanxin|Chen, Wei|Li, Tao
PMID: 29115534
Journal: J Agric Food Chem. 2018 Jan 24;66(3):602-612.
Title: Zerumbone, a Cyclic Sesquiterpene from Zingiber zerumbet Induces Apoptosis, Cell Cycle Arrest, and Antimigratory Effects in SW480 Colorectal Cancer Cells.
Author: Sithara, Thomas|Dhanya, B P|Arun, K B|Sini, Suresh|Dan, Mathew|Kokkuvayil Vasu, Radhakrishnan|Nisha, P
PMID: 29276946
Journal: Cancer Cell Int. 2018 Jan 4;18:4.
Title: Effect of long non-coding RNA Gas5 on proliferation, migration, invasion and apoptosis of colorectal cancer HT-29 cell line.
Author: Li, Jin|Wang, Yuan|Zhang, Cheng-Gong|Xiao, Hai-Juan|Hou, Jun-Ming|He, Jing-Dong
PMID: 29308053
Journal: Anticancer Res. 2018 Feb;38(2):745-751.
Title: Acetaminophen and Metamizole Induce Apoptosis in HT 29 and SW 480 Colon Carcinoma Cell Lines In Vitro.
Author: Bundscherer, Anika C|Malsy, Manuela|Gruber, Michael A|Graf, Bernhard M|Sinner, Barbara
PMID: 29374698
Journal: Oncotarget. 2017 Dec 4;9(3):3278-3291.
Title: Vitexin induces apoptosis by suppressing autophagy in multi-drug resistant colorectal cancer cells.
Author: Bhardwaj, Monika|Cho, Hee Jun|Paul, Souren|Jakhar, Rekha|Khan, Imran|Lee, Seon-Jin|Kim, Bo-Yeon|Krishnan, Manigandan|Khaket, Tejinder Pal|Lee, Hee Gu|Kang, Sun Chul
PMID: 29423046
Journal: Dig Dis Sci. 2018 Apr;63(4):900-909.
Title: Chemoprevention by Probiotics During 1,2-Dimethylhydrazine-Induced Colon Carcinogenesis in Rats.
Author: Walia, Sohini|Kamal, Rozy|Dhawan, D K|Kanwar, S S
PMID: 29427224
Journal: Med Sci Monit. 2018 Mar 9;24:1424-1433.
Title: Overexpression of Nitrogen Permease Regulator Like-2 (NPRL2) Enhances Sensitivity to Irinotecan (CPT-11) in Colon Cancer Cells by Activating the DNA Damage Checkpoint Pathway.
Author: Liu, Shasha|Liu, Bingrong
PMID: 29519997
Journal: Phytother Res. 2018 Jul;32(7):1297-1303.
Title: An Asparagus polysaccharide fraction inhibits MDSCs by inducing apoptosis through toll-like receptor 4.
Author: Zhang, Wensheng|He, Wanzhuo|Shi, Xiaodong|Li, Xiao|Wang, Yuanyuan|Hu, Minghua|Ma, Fangli|Tao, Ning|Wang, Guiqin|Qin, Zhihai
PMID: 29532545
Journal: Oncol Lett. 2018 Apr;15(4):4463-4470.
Title: Wogonoside inhibits cell growth and induces mitochondrial-mediated autophagy-related apoptosis in human colon cancer cells through the PI3K/AKT/mTOR/p70S6K signaling pathway.
Author: Han, Chengzheng|Xing, Guozheng|Zhang, Mengying|Zhong, Min|Han, Zhen|He, Chiyi|Liu, Xiaoping
PMID: 29541215
Journal: Eur J Med Chem. 2018 Apr 25;150:851-863.
Title: Design and synthesis of novel pyrrolo[2,3-a]carbazoles: 7-Chloro-2-oxo-3a-(2'-oxo-2',3'-dihydro-1'H-indol-3'-yl)-2,3,3a,4,5,10-hexahydro- pyrrolo[3,2-a]carbazole-1-carbonitrile as an efficient anticancer agent.
Author: Sathiyachandran, Perumal|Manogaran, Prasath|Nesterov, Vladimir N|Padma, Viswanadha Vijaya|Rajendra Prasad, Karnam Jayarampillai
PMID: 29597168
Journal: Mini Rev Med Chem. 2018 Mar 29. pii: MRMC-EPUB-89414.
Title: Development of Promising Thiopyrimidine-Based Anti-cancer and Antimicrobial Agents: Synthesis and QSAR Analysis.
Author: Anwar, Manal M|Syam, Yasmin M|Kotb, Eman R|Elseginy, Samia A
PMID: 29600761
Journal: Drug Des Devel Ther. 2018 Mar 29;12:657-671.
Title: The apoptotic effects of Brucea javanica fruit extract against HT29 cells associated with p53 upregulation and inhibition of NF-kappaB translocation.
Author: Bagheri, Elham|Hajiaghaalipour, Fatemeh|Nyamathulla, Shaik|Salehen, Nur'Ain
PMID: 29636600
Journal: Int J Mol Sci. 2018 Apr 11;19(4). pii: ijms19041151.
Title: DK1 Induces Apoptosis via Mitochondria-Dependent Signaling Pathway in Human Colon Carcinoma Cell Lines In Vitro.
Author: Hussin, Yazmin|Aziz, Muhammad Nazirul Mubin|Che Rahim, Nurul Fattin|Yeap, Swee Keong|Mohamad, Nurul Elyani|Masarudin, Mas Jaffri|Nordin, Noraini|Abd Rahman, Nik Mohd Afizan-Nik|Yong, Chean Yeah|Akhtar, Muhammad Nadeem|Zamrus, Siti Noor Hajar|Alitheen, Noo
PMID: 29641445
Journal: Food Funct. 2018 Apr 25;9(4):2145-2157.
Title: The inhibitory effect of Manuka honey on human colon cancer HCT-116 and LoVo cell growth. Part 1: the suppression of cell proliferation, promotion of apoptosis and arrest of the cell cycle.
Author: Afrin, Sadia|Giampieri, Francesca|Gasparrini, Massimiliano|Forbes-Hernandez, Tamara Y|Cianciosi, Danila|Reboredo-Rodriguez, Patricia|Amici, Adolfo|Quiles, Jose L|Battino, Maurizio
PMID: 29645049
Journal: Apoptosis. 2018 May 12. pii: 10.1007/s10495-018-1457-8.
Title: Resveratrol analogue, (E)-N-(2-(4-methoxystyryl) phenyl) furan-2-carboxamide induces G2/M cell cycle arrest through the activation of p53-p21(CIP1/WAF1) in human colorectal HCT116 cells.
Author: Cheah, Foo Kit|Leong, Kok Hoong|Thomas, Noel Francis|Chin, Hui Kee|Ariffin, Azhar|Awang, Khalijah
PMID: 29754265
Journal: PLoS One. 2018 May 17;13(5):e0197563.
Title: Antitumor, antioxidant and anti-inflammatory activities of kaempferol and its corresponding glycosides and the enzymatic preparation of kaempferol.
Author: Wang, Jingqiu|Fang, Xianying|Ge, Lin|Cao, Fuliang|Zhao, Linguo|Wang, Zhenzhong|Xiao, Wei
PMID: 29771951
Journal: Asian Pac J Cancer Prev. 2018 May 26;19(5):1277-1280.
Title: Expression Level of Caspase Genes in Colorectal Cancer
Author: Asadi, Milad|Shanehbandi, Dariush|Asvadi Kermani, Touraj|Sanaat, Zohreh|Zafari, Venus|Hashemzadeh, Shahriyar
PMID: 29801534
Journal: Oncol Lett. 2018 Jun;15(6):8695-8702.
Title: Upregulation of let-7f-5p promotes chemotherapeutic resistance in colorectal cancer by directly repressing several pro-apoptotic proteins.
Author: Tie, Yateng|Chen, Chong|Yang, Yanli|Qian, Zhen|Yuan, Hang|Wang, Huan|Tang, Haili|Peng, Yao|Du, Xilin|Liu, Bin
PMID: 29805607
Journal: Indian J Med Res. 2018 Feb;147(2):158-168.
Title: C-glycosyl flavone from Urginea indica inhibits proliferation & angiogenesis & induces apoptosis via cyclin-dependent kinase 6 in human breast, hepatic & colon cancer cell lines.
Author: Bevara, Ganesh Babu|Naveen Kumar, A D|Koteshwaramma, K Laxmi|Badana, Anil|Kumari, Seema|Malla, Rama Rao
PMID: 29806604
Journal: Oncol Lett. 2018 Jun;15(6):8237-8244.
Title: LncRNA BX357664 inhibits cell proliferation and invasion and promotes cell apoptosis in human colorectal cancer cells.
Author: Liu, Fengjun|Wang, Xinsheng|Liu, Haiyan|Wang, Yang|Liu, Xiaoqian|Hao, Xiaochen|Li, Hongguang
PMID: 29844809
Journal: Cell Death Discov. 2018 May 23;4:61.
Title: Dasatinib reduces 5-Fu-triggered apoptosis in colon carcinoma by directly modulating Src-dependent caspase-9 phosphorylation.
Author: Fu, Yang|Yang, Ge|Xue, Peipei|Guo, Luwei|Yin, Yuhan|Ye, Zhiqiang|Peng, Sanfei|Qin, Yanru|Duan, Qiuhong|Zhu, Feng
PMID: 29844931
Journal: Int J Biol Macromol. 2018 Oct 1;117:1050-1057.
Title: Pea lectin inhibits cell growth by inducing apoptosis in SW480 and SW48 cell lines.
Author: Islam, Farhadul|Gopalan, Vinod|Lam, Alfred K-Y|Kabir, Syed Rashel
PMID: 29885391
Journal: Int J Mol Med. 2018 Sep;42(3):1295-1304.
Title: Artesunate induces apoptosis and autophagy in HCT116 colon cancer cells, and autophagy inhibition enhances the artesunateinduced apoptosis.
Author: Jiang, Feng|Zhou, Jin-Yong|Zhang, Dan|Liu, Ming-Hao|Chen, Yu-Gen
PMID: 29901098
Journal: J Agric Food Chem. 2018 Jul 11;66(27):7054-7064.
Title: Ellagitannins from Pomegranate Ameliorates 5-Fluorouracil-Induced Intestinal Mucositis in Rats while Enhancing Its Chemotoxicity against HT-29 Colorectal Cancer Cells through Intrinsic Apoptosis Induction.
Author: Chen, Xiao-Xin|Lam, Kargo Kar-Ho|Feng, Yi-Bin|Xu, Kai|Sze, Stephen Cho-Wing|Tang, Sydney Chi-Wai|Leung, George Pak-Hen|Lee, Calvin Kai-Fai|Shi, Jun|Yang, Zhi-Jun|Li, Sheng-Tao|Zhang, Zhang-Jin|Zhang, Kalin Yan-Bo
PMID: 29920075
Journal: Biomol Ther (Seoul). 2018 Jun 21. pii: biomolther.2018.047.
Title: Shikonin Exerts Cytotoxic Effects in Human Colon Cancers by Inducing Apoptotic Cell Death via the Endoplasmic Reticulum and Mitochondria-Mediated Pathways.
Author: Han, Xia|Kang, Kyoung Ah|Piao, Mei Jing|Zhen, Ao Xuan|Hyun, Yu Jae|Kim, Hyun Min|Ryu, Yea Seong|Hyun, Jin Won
PMID: 29925224
Journal: Cell Physiol Biochem. 2018;47(4):1432-1441.
Title: Knockdown of MiR-20a Enhances Sensitivity of Colorectal Cancer Cells to Cisplatin by Increasing ASK1 Expression.
Author: Zhang, Luyao|He, Liang|Zhang, Hua|Chen, Yan
PMID: 29940575
Journal: J Inorg Biochem. 2018 Sep;186:162-175.
Title: Selective Cu(I) complex with phosphine-peptide (SarGly) conjugate contra breast cancer: Synthesis, spectroscopic characterization and insight into cytotoxic action.
Author: Komarnicka, Urszula K|Koziel, Sandra|Starosta, Radoslaw|Kyziol, Agnieszka
PMID: 29945023
Journal: ACS Omega. 2018 Feb 28;3(2):1470-1481.
Title: Impairing Powerhouse in Colon Cancer Cells by Hydrazide-Hydrazone-Based Small Molecule.
Author: Patil, Sohan|Kuman, Meenu Mahesh|Palvai, Sandeep|Sengupta, Poulomi|Basu, Sudipta
PMID: 30023806
Journal: Cell Death Dis. 2018 Jul 23;9(8):798.
Title: Suppression of Notch1 and AKT mediated epithelial to mesenchymal transition by Verrucarin J in metastatic colon cancer.
Author: Pal, Deeksha|Tyagi, Ashish|Chandrasekaran, Balaji|Alattasi, Houda|Ankem, Murali K|Sharma, Arun K|Damodaran, Chendil
PMID: 30038258
Journal: Braz J Med Biol Res. 2018 Aug 6;51(10):e7151.
Title: Icariin reduces human colon carcinoma cell growth and metastasis by enhancing p53 activities.
Author: Tian, Meili|Yang, Shuang|Yan, Xinpeng
PMID: 30088538
Journal: Oncol Lett. 2018 Oct;16(4):4193-4200.
Title: Sorbus commixta water extract induces apoptotic cell death via a ROS-dependent pathway.
Author: Moon, Seong-Cheol|Choi, Hee-Jung|Chung, Tae-Wook|Lee, Jung-Hee|Lee, Syng-Ook|Jung, Myeong Ho|Kim, Byung Joo|Choi, Jun-Yong|Ha, Ki-Tae
PMID: 30197667
Journal: Bioorg Chem. 2018 Sep 7;81:425-432.
Title: Tumor-associated carbonic anhydrase isoform IX and XII inhibitory properties of certain isatin-bearing sulfonamides endowed with in vitro antitumor activity towards colon cancer.
Author: Eldehna, Wagdy M|Nocentini, Alessio|Al-Rashood, Sara T|Hassan, Ghada S|Alkahtani, Hamad M|Almehizia, Abdulrahman A|Reda, Ahmed M|Abdel-Aziz, Hatem A|Supuran, Claudiu T
PMID: 30219719
Journal: Pharmacology. 2018 Sep 18;102(5-6):262-271.
Title: MPT0B169 and MPT0B002, New Tubulin Inhibitors, Induce Growth Inhibition, G2/M Cell Cycle Arrest, and Apoptosis in Human Colorectal Cancer Cells.
Author: Lee, Chih-Hsin|Lin, Yuan-Feng|Chen, Yen-Chou|Wong, Shuit-Mun|Juan, Shu-Hui|Huang, Huei-Mei
PMID: 30227438
Journal: BMC Cell Biol. 2018 Sep 25;19(1):21.
Title: Tanshinone IIA reduces SW837 colorectal cancer cell viability via the promotion of mitochondrial fission by activating JNK-Mff signaling pathways.
Author: Jieensinue, Sayilaxi|Zhu, Hong|Li, Guangcheng|Dong, Keli|Liang, Meiting|Li, Yayue
PMID: 30253740
Journal: Res Pharm Sci. 2018 Oct;13(5):404-412.
Title: Cytotoxic effect of methanolic extract, alkaloid and terpenoid fractions of Stachys pilifera against HT-29 cell line.
Author: Kokhdan, Esmaeel Panahi|Sadeghi, Hossein|Ghafoori, Hossin|Sadeghi, Heibatollah|Danaei, Nazanin|Javadian, Hamedreza|Aghamaali, Mahmoud Reza
PMID: 30271442
Journal: Cancer Sci. 2018 Oct 5.
Title: Possible role of p53/Mieap-regulated mitochondrial quality control as a tumor suppressor in human breast cancer.
Author: Gaowa, Siqin|Futamura, Manabu|Tsuneki, Masayuki|Kamino, Hiroki|Tajima, Jesse Y|Mori, Ryutaro|Arakawa, Hirofumi|Yoshida, Kazuhiro
PMID: 30290054
Journal: Biomed Res Int. 2018 Sep 27;2018:2548378.
Title: alpha-Hederin Arrests Cell Cycle at G2/M Checkpoint and Promotes Mitochondrial Apoptosis by Blocking Nuclear Factor-kappaB Signaling in Colon Cancer Cells.
Author: Sun, Dongdong|Shen, Weixing|Zhang, Feng|Fan, Huisen|Tan, Jiani|Li, Liu|Xu, Changliang|Zhang, Haibin|Yang, Ye|Cheng, Haibo
PMID: 30363706