Primary Site >> Colorectal Cancer
Gene >> CASP9
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Ref: Photodynamic therapy with the phthalocyanine photosensitizer Pc 4 of SW480 human colon cancer xenografts in athymic mice. PMID: 10815928 Ref: The caspase 9 inhibitor Z-LEHD-FMK protects human liver cells while permitting death of cancer cells exposed to tumor necrosis factor-related apoptosis-inducing ligand. PMID: 11103780 |
Ref: The dependence receptor DCC (deleted in colorectal cancer) defines an alternative mechanism for caspase activation. PMID: 11248093 Ref: Caspase 7 downregulation as an immunohistochemical marker of colonic carcinoma. PMID: 11381362 Ref: TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer. PMID: 11408476 Ref: The monoclonal antibody 225 activates caspase-8 and induces apoptosis through a tumor necrosis factor receptor family-independent pathway. PMID: 11439335 Ref: Induction of apoptosis in human colon carcinoma cells HT29 by sublethal cryo-injury: mediation by cytochrome c release. PMID: 11477556 Ref: A Fas-associated death domain protein-dependent mechanism mediates the apoptotic action of non-steroidal anti-inflammatory drugs in the human leukemic Jurkat cell line. PMID: 11514566 Ref: Molecular mechanisms of apoptosis induced by magnolol in colon and liver cancer cells. PMID: 11746819 |
Ref: Requirement of BAX for TRAIL/Apo2L-induced apoptosis of colorectal cancers: synergism with sulindac-mediated inhibition of Bcl-x(L). PMID: 11912124 Ref: The p53 stabilizing compound CP-31398 induces apoptosis by activating the intrinsic Bax/mitochondrial/caspase-9 pathway. PMID: 12027451 Ref: Augmentation of sodium butyrate-induced apoptosis by phosphatidylinositol 3'-kinase inhibition in the KM20 human colon cancer cell line. PMID: 12060639 Ref: Defining characteristics of Types I and II apoptotic cells in response to TRAIL. PMID: 12407450 Ref: Heat shock protects HCT116 and H460 cells from TRAIL-induced apoptosis. PMID: 12460647 Ref: Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells. PMID: 12507932 |
Ref: Butyrate induced Caco-2 cell apoptosis is mediated via the mitochondrial pathway. PMID: 12477768 Ref: Human colon cancer cells differ in their sensitivity to curcumin-induced apoptosis and heat shock protects them by inhibiting the release of apoptosis-inducing factor and caspases. PMID: 12633846 Ref: Effect of Bax deficiency on death receptor 5 and mitochondrial pathways during endoplasmic reticulum calcium pool depletion-induced apoptosis. PMID: 12730681 Ref: Precursor peptide progastrin(1-80) reduces apoptosis of intestinal epithelial cells and upregulates cytochrome c oxidase Vb levels and synthesis of ATP. PMID: 12881229 Ref: Pro-apoptotic activity of transiently expressed BCL-2 occurs independent of BAX and BAK. PMID: 12898509 Ref: The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells. PMID: 12902978 Ref: Regulation of caspase expression and apoptosis by adenomatous polyposis coli. PMID: 12907606 Ref: Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy. PMID: 14645705 |
Ref: Tocotrienol-rich fraction of palm oil activates p53, modulates Bax/Bcl2 ratio and induces apoptosis independent of cell cycle association. PMID: 14712090 Ref: Deleted in oral cancer-1 expression upregulates proapoptosis elements in microsatellite-unstable human colorectal cancer. PMID: 14761923 Ref: Induction of apoptosis and down-regulation of Bcl-XL in cancer cells by a novel small molecule, 2[[3-(2,3-dichlorophenoxy)propyl]amino]ethanol. PMID: 14871845 Ref: Cyclooxygenase-2 (COX-2)-dependent and -independent anticarcinogenic effects of celecoxib in human colon carcinoma cells. PMID: 15041464 Ref: Role of caspase activation in butyrate-induced terminal differentiation of HT29 colon carcinoma cells. PMID: 15047183 Ref: Sulforaphane-induced G2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25C. PMID: 15073169 Ref: CD44 negatively regulates apoptosis in murine colonic epithelium via the mitochondrial pathway. PMID: 15126101 Ref: Oncogenic Ras promotes butyrate-induced apoptosis through inhibition of gelsolin expression. PMID: 15213223 Ref: CD44 promotes resistance to apoptosis in human colon cancer cells. PMID: 15215046 Ref: Death induction by recombinant native TRAIL and its prevention by a caspase 9 inhibitor in primary human esophageal epithelial cells. PMID: 15226295 Ref: Unconjugated bilirubin induces apoptosis in colon cancer cells by triggering mitochondrial depolarization. PMID: 15382069 Ref: Atiprimod is an inhibitor of cancer cell proliferation and angiogenesis. PMID: 15844657 |
Ref: Combination of 5-fluorouracil and N1,N11-diethylnorspermine markedly activates spermidine/spermine N1-acetyltransferase expression, depletes polyamines, and synergistically induces apoptosis in colon carcinoma cells. PMID: 15546879 Ref: Different apoptotic mechanisms are involved in the antiproliferative effects of 7beta-hydroxysitosterol and 7beta-hydroxycholesterol in human colon cancer cells. PMID: 15550935 Ref: In vitro and in vivo evaluation of NCX 4040 cytotoxic activity in human colon cancer cell lines. PMID: 15691389 Ref: HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo. PMID: 15846298 Ref: Justicidin A decreases the level of cytosolic Ku70 leading to apoptosis in human colorectal cancer cells. PMID: 15905197 Ref: Reactive oxygen species regulate caspase activation in tumor necrosis factor-related apoptosis-inducing ligand-resistant human colon carcinoma cell lines. PMID: 16103097 Ref: A novel isoform of TUCAN is overexpressed in human cancer tissues and suppresses both caspase-8- and caspase-9-mediated apoptosis. PMID: 16204039 Ref: Sulindac sulfide-induced apoptosis is enhanced by a small-molecule Bcl-2 inhibitor and by TRAIL in human colon cancer cells overexpressing Bcl-2. PMID: 16227396 Ref: Chemotherapy regimen GOLF induces apoptosis in colon cancer cells through multi-chaperone complex inactivation and increased Raf-1 ubiquitin-dependent degradation. PMID: 16294035 |
Ref: Increased expression of high mobility group box 1 (HMGB1) is associated with an elevated level of the antiapoptotic c-IAP2 protein in human colon carcinomas. PMID: 16118352 Ref: Comparative effects of RRR-alpha- and RRR-gamma-tocopherol on proliferation and apoptosis in human colon cancer cell lines. PMID: 16417629 Ref: The dietary hydrolysable tannin punicalagin releases ellagic acid that induces apoptosis in human colon adenocarcinoma Caco-2 cells by using the mitochondrial pathway. PMID: 16426830 Ref: The dependence receptor DCC requires lipid raft localization for cell death signaling. PMID: 16537496 Ref: Induction of apoptosis by hexaminolevulinate-mediated photodynamic therapy in human colon carcinoma cell line 320DM. PMID: 16566715 Ref: Caspase-2 triggers Bax-Bak-dependent and -independent cell death in colon cancer cells treated with resveratrol. PMID: 16617056 Ref: Checkpoint kinase 1-mediated phosphorylation of Cdc25C and bad proteins are involved in antitumor effects of loratadine-induced G2/M phase cell-cycle arrest and apoptosis. PMID: 16649252 Ref: Mutational analysis of proapoptotic caspase-9 gene in common human carcinomas. PMID: 16689829 Ref: Fas-associated phosphatase-1 promotes Fas-mediated apoptosis in human colon cancer cells: novel function of FAP-1. PMID: 16706817 Ref: Apoptotic effects of over-expressed estrogen receptor-beta on LoVo colon cancer cell is mediated by p53 signalings in a ligand-dependent manner. PMID: 16830793 Ref: Bak functionally complements for loss of Bax during p14ARF-induced mitochondrial apoptosis in human cancer cells. PMID: 16847458 Ref: [Study on the effects of mitochondrial pathways on apoptosis in colon carcinoma cells induced by tumor necrosis factor related apoptosis inducing ligand]. PMID: 17143800 Ref: p21 blocks irradiation-induced apoptosis downstream of mitochondria by inhibition of cyclin-dependent kinase-mediated caspase-9 activation. PMID: 17145870 Ref: Trichostatin A induces apoptosis in lung cancer cells via simultaneous activation of the death receptor-mediated and mitochondrial pathway? PMID: 17202837 |
Ref: Pinocembrin triggers Bax-dependent mitochondrial apoptosis in colon cancer cells. PMID: 17186548 Ref: Lack of p53 augments thymoquinone-induced apoptosis and caspase activation in human osteosarcoma cells. PMID: 17218778 Ref: Induction of apoptosis in DLD-1 human colon cancer cells by peridinin isolated from the dinoflagellate, Heterocapsa triquetra. PMID: 17420600 Ref: 5-Aminoimidazole-4-carboxamide riboside sensitizes TRAIL- and TNF{alpha}-induced cytotoxicity in colon cancer cells through AMP-activated protein kinase signaling. PMID: 17513605 Ref: Low-dose BBR3610 toxicity in colon cancer cells is p53-independent and enhanced by inhibition of epidermal growth factor receptor (ERBB1)-phosphatidyl inositol 3 kinase signaling. PMID: 17578896 Ref: Effect of methanolic extract from silkworm droppings on proliferation and caspase activity in HT-29 human colon cancer cells. PMID: 17887940 Ref: Study of molecular mechanisms of pro-apoptotic activity of NCX 4040, a novel nitric oxide-releasing aspirin, in colon cancer cell lines. PMID: 17971198 |
Ref: Effect of hyperthermia and chemotherapeutic agents on TRAIL-induced cell death in human colon cancer cells. PMID: 17520700 Ref: Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon. PMID: 17823781 Ref: Licofelone, a dual COX/5-LOX inhibitor, induces apoptosis in HCA-7 colon cancer cells through the mitochondrial pathway independently from its ability to affect the arachidonic acid cascade. PMID: 18033773 Ref: Cytotoxic and antioxidant activity of 4-methylthio-3-butenyl isothiocyanate from Raphanus sativus L. (Kaiware Daikon) sprouts. PMID: 18189352 Ref: Growth inhibitory effects of obovatol through induction of apoptotic cell death in prostate and colon cancer by blocking of NF-kappaB. PMID: 18241858 Ref: DR5 receptor mediates anoikis in human colorectal carcinoma cell lines. PMID: 18245494 Ref: Inducing apoptosis of human colon cancer cells by an IGF-I D domain analogue peptide. PMID: 18261206 Ref: CUGBP2 downregulation by prostaglandin E2 protects colon cancer cells from radiation-induced mitotic catastrophe. PMID: 18325984 Ref: Potent antitumor efficacy of ST13 for colorectal cancer mediated by oncolytic adenovirus via mitochondrial apoptotic cell death. PMID: 18355116 Ref: Signaling and regulatory mechanisms of integrin alphavbeta6 on the apoptosis of colon cancer cells. PMID: 18381232 Ref: Crude extracts of Solanum lyratum induced cytotoxicity and apoptosis in a human colon adenocarcinoma cell line (colo 205). PMID: 18507053 Ref: PPARgamma is involved in mesalazine-mediated induction of apoptosis and inhibition of cell growth in colon cancer cells. PMID: 18544567 Ref: A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma. PMID: 18560353 Ref: [Overcoming acquired resistance to tumor necrosis factor-related apoptosis-inducing ligand by Bcl-XL small interfering RNA in human colon cancer]. PMID: 18788624 Ref: [Role of high mobility group box 1 in adriamycin-induced apoptosis in leukemia K562 cells]. PMID: 18799030 Ref: Hexane/ethanol extract of Glycyrrhiza uralensis licorice suppresses doxorubicin-induced apoptosis in H9c2 rat cardiac myoblasts. PMID: 18849542 Ref: Induction of Noxa sensitizes human colorectal cancer cells expressing Mcl-1 to the small-molecule Bcl-2/Bcl-xL inhibitor, ABT-737. PMID: 19088028 |
Ref: Maslinic acid, a natural triterpene from Olea europaea L., induces apoptosis in HT29 human colon-cancer cells via the mitochondrial apoptotic pathway. PMID: 18790561 Ref: Plaunotol and geranylgeraniol induce caspase-mediated apoptosis in colon cancer. PMID: 18805546 Ref: Age-related differential responses to curcumin-induced apoptosis during the initiation of colon cancer in rats. PMID: 19095035 Ref: Formosanin C-induced apoptosis requires activation of caspase-2 and change of mitochondrial membrane potential. PMID: 19154411 Ref: Biphasic regulation of cell death and survival by hydrophobic bile acids in HCT116 cells. PMID: 19373611 Ref: Sorafenib and vorinostat kill colon cancer cells by CD95-dependent and -independent mechanisms. PMID: 19483104 Ref: Novel functional profiling approach combining reverse phase protein microarrays and human 3-D ex vivo tissue cultures: expression of apoptosis-related proteins in human colon cancer. PMID: 19609961 Ref: A novel histone deacetylase inhibitor, CG0006, induces cell death through both extrinsic and intrinsic apoptotic pathways. PMID: 19644355 Ref: Ursolic acid inhibits proliferation and induces apoptosis of HT-29 colon cancer cells by inhibiting the EGFR/MAPK pathway. PMID: 19735099 Ref: A novel pro-apoptotic function of RACK1: suppression of Src activity in the intrinsic and Akt pathways. PMID: 19767770 Ref: Apoptosis inducing activity of fucoidan in HCT-15 colon carcinoma cells. PMID: 19801840 Ref: Compound K induces apoptosis via CAMK-IV/AMPK pathways in HT-29 colon cancer cells. PMID: 19845353 Ref: trans-10,cis-12 Conjugated linoleic acid induces depolarization of mitochondrial membranes in HT-29 human colon cancer cells: a possible mechanism for induction of apoptosis. PMID: 19857056 Ref: Novel anticancer activity of the autocleaved ovotransferrin against human colon and breast cancer cells. PMID: 19886663 Ref: A combination of indol-3-carbinol and genistein synergistically induces apoptosis in human colon cancer HT-29 cells by inhibiting Akt phosphorylation and progression of autophagy. PMID: 19909554 Ref: The anticancer effects of sodium selenite and selenomethionine on human colorectal carcinoma cell lines in nude mice. PMID: 19911698 Ref: Curcumin induces caspase and calpain-dependent apoptosis in HT29 human colon cancer cells. PMID: 21475877 |
Ref: Lysosomal destabilization and cathepsin B contributes for cytochrome c release and caspase activation in embelin-induced apoptosis. PMID: 19943316 Ref: Expression and prognostic significance of APAF-1, caspase-8 and caspase-9 in stage II/III colon carcinoma: caspase-8 and caspase-9 is associated with poor prognosis. PMID: 20013803 Ref: Modulation of stress genes expression profile by nitric oxide-releasing aspirin in Jurkat T leukemia cells. PMID: 20188076 Ref: Role of fatty acid chain length on the induction of apoptosis by newly synthesized catechin derivatives. PMID: 20206613 Ref: Arctigenin blocks the unfolded protein response and shows therapeutic antitumor activity. PMID: 20232300 Ref: Pleurospermum kamtschaticum extract induces apoptosis via mitochondrial pathway and NAG-1 expression in colon cancer cells. PMID: 20378978 Ref: Systematic genetic dissection of p14ARF-mediated mitochondrial cell death signaling reveals a key role for p21CDKN1 and the BH3-only protein Puma/bbc3. PMID: 20419447 Ref: Suppression of NF-kappaB and GSK-3beta is involved in colon cancer cell growth inhibition by the PPAR agonist troglitazone. PMID: 20540935 Ref: Allyl isothiocyanate triggers G2/M phase arrest and apoptosis in human brain malignant glioma GBM 8401 cells through a mitochondria-dependent pathway. PMID: 20596632 Ref: A glycoprotein from Laminaria japonica induces apoptosis in HT-29 colon cancer cells. PMID: 20615460 Ref: PI3-kinase/Wnt association mediates COX-2/PGE(2) pathway to inhibit apoptosis in early stages of colon carcinogenesis: chemoprevention by diclofenac. PMID: 20617408 Ref: Evodiamine induces caspase-dependent apoptosis and S phase arrest in human colon lovo cells. PMID: 20647931 Ref: Tian Xian Liquid (TXL) induces apoptosis in HT-29 colon cancer cell in vitro and inhibits tumor growth in vivo. PMID: 20663169 Ref: Isoprenoid geranylgeranylacetone inhibits human colon cancer cells through induction of apoptosis and cell cycle arrest. PMID: 20724917 Ref: Fucoidan present in brown algae induces apoptosis of human colon cancer cells. PMID: 20727207 Ref: Oleanane-type triterpenoids from Panax stipuleanatus and their anticancer activities. PMID: 20951582 Ref: 20(S)-Ginsenoside Rg3-induced apoptosis in HT-29 colon cancer cells is associated with AMPK signaling pathway. PMID: 21472321 Ref: Compound K, a metabolite of ginseng saponin, induces mitochondria-dependent and caspase-dependent apoptosis via the generation of reactive oxygen species in human colon cancer cells. PMID: 21614182 |
Ref: Sequential caspase-2 and caspase-8 activation is essential for saikosaponin a-induced apoptosis of human colon carcinoma cell lines. PMID: 21107704 Ref: Apoptosis-inducing effect of diketopiperazine disulfides produced by Aspergillus sp. KMD 901 isolated from marine sediment on HCT116 colon cancer cell lines. PMID: 21122037 Ref: Phloroglucinol derivative MCPP induces cell apoptosis in human colon cancer. PMID: 21268086 Ref: MiR-148a promotes apoptosis by targeting Bcl-2 in colorectal cancer. PMID: 21455217 Ref: Deltonin, a steroidal saponin, inhibits colon cancer cell growth in vitro and tumor growth in vivo via induction of apoptosis and antiangiogenesis. PMID: 21471712 Ref: LYG-202 inhibits the proliferation of human colorectal carcinoma HCT-116 cells through induction of G1/S cell cycle arrest and apoptosis via p53 and p21(WAF1/Cip1) expression. PMID: 21491996 Ref: Obacunone and obacunone glucoside inhibit human colon cancer (SW480) cells by the induction of apoptosis. PMID: 21515332 Ref: The natural triterpene maslinic acid induces apoptosis in HT29 colon cancer cells by a JNK-p53-dependent mechanism. PMID: 21524306 Ref: Polymorphisms of caspase 8 and caspase 9 gene and colorectal cancer susceptibility and prognosis. PMID: 21538054 Ref: Effects of alpha-mangostin on apoptosis induction of human colon cancer. PMID: 21547127 Ref: Concomitant activation of caspase-9 and down-regulation of IAP proteins as a mechanism of apoptotic death in HepG2, T47D and HCT-116 cells upon exposure to a derivative from 4-aryl-4H-chromenes family. PMID: 21565459 Ref: Lobaplatin suppresses proliferation and induces apoptosis in the human colorectal carcinoma cell Line LOVO in vitro. PMID: 21612887 Ref: Calbindin 2 (CALB2) regulates 5-fluorouracil sensitivity in colorectal cancer by modulating the intrinsic apoptotic pathway. PMID: 21629658 Ref: [Expression of caspase apoptosis pathway genes mRNA in colorectal cancer and polyps]. PMID: 21671482 Ref: Oxaliplatin sensitizes human colon cancer cells to TRAIL through JNK-dependent phosphorylation of Bcl-xL. PMID: 21683075 Ref: Enormous influence of TNIK knockdown on intracellular signals and cell survival. PMID: 21710359 Ref: Deoxycholic and chenodeoxycholic bile acids induce apoptosis via oxidative stress in human colon adenocarcinoma cells. PMID: 21789651 Ref: Mechanism of Alternariol monomethyl ether-induced mitochondrial apoptosis in human colon carcinoma cells. PMID: 22001388 Ref: Small interfering RNA targeting mcl-1 enhances proteasome inhibitor-induced apoptosis in various solid malignant tumors. PMID: 22078414 Ref: Human Embryonic-like ECM (hECM) Stimulates Proliferation and Differentiation in Stem Cells While Killing Cancer Cells. PMID: 24298336 |
Ref: Cardamonin sensitizes tumour cells to TRAIL through ROS- and CHOP-mediated up-regulation of death receptors and down-regulation of survival proteins. PMID: 21797841 Ref: PEG-liposomal oxaliplatin induces apoptosis in human colorectal cancer cells via Fas/FasL and caspase-8. PMID: 21888623 Ref: Sanguinarine induces apoptosis of HT-29 human colon cancer cells via the regulation of Bax/Bcl-2 ratio and caspase-9-dependent pathway. PMID: 22215411 Ref: Targeting colorectal cancer stem cells with inducible caspase-9. PMID: 22223359 Ref: Widdrol induces apoptosis via activation of AMP-activated protein kinase in colon cancer cells. PMID: 22266984 Ref: A mitochondria-mediated apoptotic pathway induced by deoxynivalenol in human colon cancer cells. PMID: 22269384 Ref: 5-Fluorouracil-loaded poly(epsilon-caprolactone) nanoparticles combined with phage E gene therapy as a new strategy against colon cancer. PMID: 22275826 Ref: Silencing of the polyamine catabolic key enzyme SSAT prevents CDK inhibitor-induced apoptosis in Caco-2 colon cancer cells. PMID: 22294330 Ref: Antitumor effects of emodin on LS1034 human colon cancer cells in vitro and in vivo: roles of apoptotic cell death and LS1034 tumor xenografts model. PMID: 22321733 Ref: Paeoniflorin inhibits growth of human colorectal carcinoma HT 29 cells in vitro and in vivo. PMID: 22326807 Ref: Piroxicam and C-phycocyanin mediated apoptosis in 1,2-dimethylhydrazine dihydrochloride induced colon carcinogenesis: exploring the mitochondrial pathway. PMID: 22369161 Ref: Ginsenoside compound K, not Rb1, possesses potential chemopreventive activities in human colorectal cancer. PMID: 22426808 Ref: Loss of giant obscurins promotes breast epithelial cell survival through apoptotic resistance. PMID: 22441987 Ref: Caspase-mediated pro-apoptotic interaction of panaxadiol and irinotecan in human colorectal cancer cells. PMID: 22471369 Ref: Ursodeoxycholic acid protects colon cancer HCT116 cells from deoxycholic acid-induced apoptosis by inhibiting apoptosome formation. PMID: 22497644 Ref: Prognostic Impact of Polymorphisms in the CASPASE Genes on Survival of Patients with Colorectal Cancer. PMID: 22500158 Ref: The role of Nrf2 and apoptotic signaling pathways in oroxylin A-mediated responses in HCT-116 colorectal adenocarcinoma cells and xenograft tumors. PMID: 22526619 Ref: Overexpression of Dickkopf-3 induces apoptosis through mitochondrial pathway in human colon cancer. PMID: 22529687 Ref: Cell death induced by the Alternaria mycotoxin Alternariol. PMID: 22542754 Ref: Noscapine induces mitochondria-mediated apoptosis in human colon cancer cells in vivo and in vitro. PMID: 22546556 Ref: Diallyl trisulfide induces apoptosis in human primary colorectal cancer cells. PMID: 22736270 Ref: Anti-invasive effects and proapoptotic activity induction by the rexinoid IIF and valproic acid in combination on colon cancer cell lines. PMID: 22753748 Ref: Escherichia coli STb toxin induces apoptosis in intestinal epithelial cell lines. PMID: 22771838 Ref: Synergistic effect of a combination of nanoparticulate Fe3O4 and gambogic acid on phosphatidylinositol 3-kinase/Akt/Bad pathway of LOVO cells. PMID: 22888247 Ref: Laminarin induces apoptosis of human colon cancer LOVO cells through a mitochondrial pathway. PMID: 22907156 Ref: The synergistic effects of low-dose irinotecan and TRAIL on TRAIL-resistant HT-29 colon carcinoma in vitro and in vivo. PMID: 22922573 Ref: Anticancer effects of KI-10F: a novel compound affecting apoptosis, angiogenesis and cell growth in colon cancer. PMID: 22941304 Ref: Cytotoxic effects of Echinacea purpurea flower extracts and cichoric acid on human colon cancer cells through induction of apoptosis. PMID: 22971663 Ref: Systems analysis of cancer cell heterogeneity in caspase-dependent apoptosis subsequent to mitochondrial outer membrane permeabilization. PMID: 23038270 Ref: Sophoridine exerts an anti-colorectal carcinoma effect through apoptosis induction in vitro and in vivo. PMID: 23069582 Ref: Phenethyl caffeate benzo[kl]xanthene lignan with DNA interacting properties induces DNA damage and apoptosis in colon cancer cells. PMID: 23123449 Ref: Survival of cancer stem cells under hypoxia and serum depletion via decrease in PP2A activity and activation of p38-MAPKAPK2-Hsp27. PMID: 23185379 Ref: Beta-asarone induces LoVo colon cancer cell apoptosis by up-regulation of caspases through a mitochondrial pathway in vitro and in vivo. PMID: 23244151 Ref: (3S)-1,2,3,4-Tetrahydro-beta-carboline-3-carboxylic acid from Cichorium endivia. L induces apoptosis of human colorectal cancer HCT-8 cells. PMID: 23275050 |
Ref: Curcumin inhibits proliferation and induces apoptosis of human colorectal cancer cells by activating the mitochondria apoptotic pathway. PMID: 22628241 Ref: The beta6-integrin-ERK/MAP kinase pathway contributes to chemo resistance in colon cancer. PMID: 23073477 Ref: Predictive markers for the response to 5-fluorouracil therapy in cancer cells: Constant-field gel electrophoresis as a tool for prediction of response to 5-fluorouracil-based chemotherapy. PMID: 23255942 Ref: Bamboo salt has in vitro anticancer activity in HCT-116 cells and exerts anti-metastatic effects in vivo. PMID: 23256441 Ref: Tautomycetin induces apoptosis by inactivating Akt through a PP1-independent signaling pathway in human breast cancer cells. PMID: 23269238 Ref: Association of CASP9, CASP10 gene polymorphisms and tea drinking with colorectal cancer risk in the Han Chinese population. PMID: 23303631 Ref: Increase of cyclooxygenase-2 inhibition with celecoxib combined with 5-FU enhances tumor cell apoptosis and antitumor efficacy in a subcutaneous implantation tumor model of human colon cancer. PMID: 23347845 Ref: Identification of novel compounds that enhance colon cancer cell sensitivity to inflammatory apoptotic ligands. PMID: 23377828 Ref: Intravenous administration of manuka honey inhibits tumor growth and improves host survival when used in combination with chemotherapy in a melanoma mouse model. PMID: 23409104 Ref: Vitexin-2-O-xyloside, raphasatin and (-)-epigallocatechin-3-gallate synergistically affect cell growth and apoptosis of colon cancer cells. PMID: 23411276 Ref: Pramanicin analog induces apoptosis in human colon cancer cells: critical roles for Bcl-2, Bim, and p38 MAPK signaling. PMID: 23441183 Ref: Cytotoxicity and modes of action of four naturally occuring benzophenones: 2,2',5,6'-tetrahydroxybenzophenone, guttiferone E, isogarcinol and isoxanthochymol. PMID: 23507522 Ref: Netrin-1 protects hypoxia-induced mitochondrial apoptosis through HSP27 expression via DCC- and integrin alpha6beta4-dependent Akt, GSK-3beta, and HSF-1 in mesenchymal stem cells. PMID: 23538444 Ref: Evaluation of apoptotic activity of new condensed pyrazole derivatives. PMID: 23568979 Ref: Association between main Caspase gene polymorphisms and the susceptibility and prognosis of colorectal cancer. PMID: 23715747 Ref: miR-129 promotes apoptosis and enhances chemosensitivity to 5-fluorouracil in colorectal cancer. PMID: 23744359 Ref: Ilex kudingcha C.J. Tseng (Kudingcha) has in vitro anticancer activities in MCF-7 human breast adenocarcinoma cells and exerts anti-metastatic effects in vivo. PMID: 23760150 Ref: Cytotoxicity and modes of action of four Cameroonian dietary spices ethno-medically used to treat cancers: Echinops giganteus, Xylopia aethiopica, Imperata cylindrica and Piper capense. PMID: 23827757 Ref: HSP90 Inhibitors, Geldanamycin and Radicicol, Enhance Fisetin-Induced Cytotoxicity via Induction of Apoptosis in Human Colonic Cancer Cells. PMID: 23840275 Ref: PBOX-15 induces apoptosis and improves the efficacy of oxaliplatin in human colorectal cancer cell lines. PMID: 23872382 Ref: A ginseng metabolite, compound K, induces autophagy and apoptosis via generation of reactive oxygen species and activation of JNK in human colon cancer cells. PMID: 23907464 Ref: Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactive oxygen species. PMID: 23916687 Ref: Cadmium modifies the cell cycle and apoptotic profiles of human breast cancer cells treated with 5-fluorouracil. PMID: 23941782 Ref: Daidzein causes cytochrome c-mediated apoptosis via the Bcl-2 family in human hepatic cancer cells. PMID: 23959101 Ref: Antitumour activity on extrinsic apoptotic targets of the triterpenoid maslinic acid in p53-deficient Caco-2 adenocarcinoma cells. PMID: 23973282 Ref: Effects of parafibromin expression on the phenotypes and relevant mechanisms in the DLD-1 colon carcinoma cell line. PMID: 23991985 Ref: Midazolam induces cellular apoptosis in human cancer cells and inhibits tumor growth in xenograft mice. PMID: 24008365 Ref: Isolation and chemopreventive evaluation of novel naphthoquinone compounds from Alkanna tinctoria. PMID: 24025561 Ref: Plant-derived mAbs have effective anti-cancer activities by increasing ganglioside expression in colon cancers. PMID: 24078119 Ref: Effects of matrine on the proliferation of HT29 human colon cancer cells and its antitumor mechanism. PMID: 24137393 Ref: A new bisphosphonate derivative, CP, induces gastric cancer cell apoptosis via activation of the ERK1/2 signaling pathway. PMID: 24241351 Ref: Galectin-3 silencing inhibits epirubicin-induced ATP binding cassette transporters and activates the mitochondrial apoptosis pathway via beta-catenin/GSK-3beta modulation in colorectal carcinoma. PMID: 24303084 Ref: Hinokitiol inhibits cell growth through induction of S-phase arrest and apoptosis in human colon cancer cells and suppresses tumor growth in a mouse xenograft experiment. PMID: 24308647 Ref: Inhibition of Wnt/beta-catenin signaling mediates ursolic acid-induced apoptosis in PC-3 prostate cancer cells. PMID: 24399733 Ref: Fermented Pu-erh tea increases in vitro anticancer activities in HT-29 cells and has antiangiogenetic effects on HUVECs. PMID: 24579782 |
Ref: N-acetyl-L-cysteine enhances fisetin-induced cytotoxicity via induction of ROS-independent apoptosis in human colonic cancer cells. PMID: 24019108 Ref: DMPPQA, a novel angiogenesis inhibitor, induces apoptosis in human colon cancer HCT-116 cells and HUVECs. PMID: 24293112 Ref: The fermented non-digestible fraction of common bean (Phaseolus vulgaris L.) triggers cell cycle arrest and apoptosis in human colon adenocarcinoma cells. PMID: 24293398 Ref: Inhibitory effects of Dendrobium candidum Wall ex Lindl. on azoxymethane- and dextran sulfate sodium-induced colon carcinogenesis in C57BL/6 mice. PMID: 24396476 Ref: Carnosol induces apoptosis through generation of ROS and inactivation of STAT3 signaling in human colon cancer HCT116 cells. PMID: 24481553 Ref: Dihydroartemisinin induces apoptosis in colorectal cancer cells through the mitochondria-dependent pathway. PMID: 24519064 Ref: Mechanisms underlying apoptosis-inducing effects of Kaempferol in HT-29 human colon cancer cells. PMID: 24549175 Ref: Tangeretin, a citrus polymethoxyflavonoid, induces apoptosis of human gastric cancer AGS cells through extrinsic and intrinsic signaling pathways. PMID: 24573532 Ref: Induction of intrinsic apoptosis pathway in colon cancer HCT-116 cells by novel 2-substituted-5,6,7,8-tetrahydronaphthalene derivatives. PMID: 24657569 Ref: A novel small-molecule YLT205 induces apoptosis in human colorectal cells via mitochondrial apoptosis pathway in vitro and inhibits tumor growth in vivo. PMID: 24713812 Ref: Epithelial membrane protein 1 negatively regulates cell growth and metastasis in colorectal carcinoma. PMID: 24744589 Ref: Antibody against N-terminal domain of phospholipid scramblase 1 induces apoptosis in colorectal cancer cells through the intrinsic apoptotic pathway. PMID: 24766818 Ref: beta1 integrin modulates tumor growth and apoptosis of human colorectal cancer. PMID: 24807392 Ref: Thymoquinone induces apoptosis in human colon cancer HCT116 cells through inactivation of STAT3 by blocking JAK2- and Srcmediated phosphorylation of EGF receptor tyrosine kinase. PMID: 24890449 Ref: Expression of survivin and p53 modulates honokiol-induced apoptosis in colorectal cancer cells. PMID: 24905183 Ref: Silencing of JMJD2B induces cell apoptosis via mitochondria-mediated and death receptor-mediated pathway activation in colorectal cancer. PMID: 24957706 Ref: Activation of JNK contributes to evodiamine-induced apoptosis and G2/M arrest in human colorectal carcinoma cells: a structure-activity study of evodiamine. PMID: 24959718 Ref: S-allylmercaptocysteine promotes MAPK inhibitor-induced apoptosis by activating the TGF-beta signaling pathway in cancer cells. PMID: 24970681 Ref: 5-Fluorouracil-induced apoptosis in colorectal cancer cells is caspase-9-dependent and mediated by activation of protein kinase C-delta PMID: 25013487 Ref: Phosphorylation status of Akt and caspase-9 in gastric and colorectal carcinomas. PMID: 25031754 Ref: Generation of ROS by CAY10598 leads to inactivation of STAT3 signaling and induction of apoptosis in human colon cancer HCT116 cells. PMID: 25096910 Ref: Combination effect of epigenetic regulation and ionizing radiation in colorectal cancer cells. PMID: 25136811 Ref: SKLB316, a novel small-molecule inhibitor of cell-cycle progression, induces G2/M phase arrest and apoptosis in vitro and inhibits tumor growth in vivo. PMID: 25301449 Ref: Paeonol exerts an anticancer effect on human colorectal cancer cells through inhibition of PGE(2) synthesis and COX-2 expression. PMID: 25322760 Ref: D. candidum has in vitro anticancer effects in HCT-116 cancer cells and exerts in vivo anti-metastatic effects in mice. PMID: 25324926 Ref: Hederagenin from the leaves of ivy (Hedera helix L.) induces apoptosis in human LoVo colon cells through the mitochondrial pathway. PMID: 25342273 Ref: Smac/DIABLO expression in human gastrointestinal carcinoma: Association with clinicopathological parameters and survivin expression. PMID: 25364431 Ref: Achyranthes aspera root extracts induce human colon cancer cell (COLO-205) death by triggering the mitochondrial apoptosis pathway and S phase cell cycle arrest. PMID: 25401123 |
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Ref: Nexrutine inhibits azoxymethane-induced colonic aberrant crypt formation in rat colon and induced apoptotic cell death in colon adenocarcinoma cells. PMID: 26259065 Ref: Depletion of histone N-terminal-acetyltransferase Naa40 induces p53-independent apoptosis in colorectal cancer cells via the mitochondrial pathway. PMID: 26666750 Ref: A serine protease extracted from Trichosanthes kirilowii induces apoptosis via the PI3K/AKT-mediated mitochondrial pathway in human colorectal adenocarcinoma cells. PMID: 26673746 Ref: Novel 1,5-diphenyl-6-substituted 1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones induced apoptosis in RKO colon cancer cells. PMID: 26677729 Ref: Thymoquinone from Nigella sativa Seeds Promotes the Antitumor Activity of Noncytotoxic Doses of Topotecan in Human Colorectal Cancer Cells in Vitro. PMID: 26848703 Ref: Growth inhibition effects of ent-11alpha-hydroxy-15-oxo-kaur-16-en-19-oic-acid on colorectal carcinoma cells and colon carcinoma-bearing mice. PMID: 26935771 Ref: Polyphenol stabilized colloidal gold nanoparticles from Abutilon indicum leaf extract induce apoptosis in HT-29 colon cancer cells. PMID: 27038915 Ref: Arctigenin induces apoptosis in colon cancer cells through ROS/p38MAPK pathway. PMID: 27061535 Ref: The Herbal Medicine Utrica Dioica Inhibits Proliferation of Colorectal Cancer Cell Line by Inducing Apoptosis and Arrest at the G2/M Phase. PMID: 27090648 Ref: Columbianadin Inhibits Cell Proliferation by Inducing Apoptosis and Necroptosis in HCT116 Colon Cancer Cells. PMID: 27098859 Ref: Dioscin Induces Apoptosis in Human Cervical Carcinoma HeLa and SiHa Cells through ROS-Mediated DNA Damage and the Mitochondrial Signaling Pathway. PMID: 27271587 Ref: Tounong Powder () extracts induce G1 cell cycle arrest and apoptosis in LoVo cells. PMID: 27358203 Ref: Engineering of caveolae-specific self-micellizing anticancer lipid nanoparticles to enhance the chemotherapeutic efficacy of oxaliplatin in colorectal cancer cells. PMID: 27395829 Ref: [Mechanism of colon cancer cell apoptosis induced by telocinobufagin: role of oxidative stress and apoptosis pathway]. PMID: 27435769 Ref: Protocatechualdehyde Induces S-Phase Arrest and Apoptosis by Stimulating the p27(KIP1)-Cyclin A/D1-CDK2 and Mitochondrial Apoptotic Pathways in HT-29 Cells. PMID: 27447597 Ref: Clausenidin induces caspase-dependent apoptosis in colon cancer. PMID: 27473055 Ref: A Ribonuclease Isolated from Wild Ganoderma Lucidum Suppressed Autophagy and Triggered Apoptosis in Colorectal Cancer Cells. PMID: 27504094 Ref: Inhibition of glucosylceramide synthase eliminates the oncogenic function of p53 R273H mutant in the epithelial-mesenchymal transition and induced pluripotency of colon cancer cells. PMID: 27517620 Ref: Crocetin exploits p53-induced death domain (PIDD) and FAS-associated death domain (FADD) proteins to induce apoptosis in colorectal cancer. PMID: 27622714 Ref: Anticancer effect of icaritin inhibits cell growth of colon cancer through reactive oxygen species, Bcl-2 and cyclin D1/E signaling. PMID: 27900033 Ref: Diterpenoid Tanshinones, the extract from Danshen (Radix Salviae Miltiorrhizae) induced apoptosis in nine human cancer cell lines. PMID: 28459519 Ref: Water extract of Galla Rhois with steaming process enhances apoptotic cell death in human colon cancer cells. PMID: 28462130 Ref: Anticancer Properties of Chrysin on Colon Cancer Cells, In vitro and In vivo with Modulation of Caspase-3, -9, Bax and Sall4. PMID: 28959334 |
Ref: siRNA-Mediated Silencing of HMGA2 Induces Apoptosis and Cell Cycle Arrest in Human Colorectal Carcinoma. PMID: 27629422 Ref: Apigenin induces both intrinsic and extrinsic pathways of apoptosis in human colon carcinoma HCT-116 cells. PMID: 27959417 Ref: MC37, a new mono-carbonyl curcumin analog, induces G2/M cell cycle arrest and mitochondria-mediated apoptosis in human colorectal cancer cells. PMID: 28024945 Ref: Novel derivative of aminobenzenesulfonamide (3c) induces apoptosis in colorectal cancer cells through ROS generation and inhibits cell migration. PMID: 28049506 Ref: Salubrinal protects against Clostridium difficile toxin B-induced CT26 cell death. PMID: 28119311 Ref: miR-433 reduces cell viability and promotes cell apoptosis by regulating MACC1 in colorectal cancer. PMID: 28123526 Ref: Novel ent-Kaurane Diterpenoid from Rubus corchorifolius L. f. Inhibits Human Colon Cancer Cell Growth via Inducing Cell Cycle Arrest and Apoptosis. PMID: 28169543 Ref: TEOA, a triterpenoid from Actinidia eriantha, induces autophagy in SW620 cells via endoplasmic reticulum stress and ROS-dependent mitophagy. PMID: 28211011 Ref: Stevioside induced cytotoxicity in colon cancer cells via reactive oxygen species and mitogen-activated protein kinase signaling pathways-mediated apoptosis. PMID: 28454400 Ref: Cisatracurium-induced proliferation impairment and death of colorectal cancer cells, HCT116 is mediated by p53 dependent intrinsic apoptotic pathway in vitro. PMID: 28463795 Ref: Secretion metabolites of probiotic yeast, Pichia kudriavzevii AS-12, induces apoptosis pathways in human colorectal cancer cell lines. PMID: 28477945 Ref: Tafazzin (TAZ) promotes the tumorigenicity of cervical cancer cells and inhibits apoptosis. PMID: 28489874 Ref: An active molecule from Pulsatilla chinensis, Pulsatilla saponin A, induces apoptosis and inhibits tumor growth of human colon cancer cells without or with 5-FU. PMID: 28529594 Ref: Isofraxidin inhibited proliferation and induced apoptosis via blockage of Akt pathway in human colorectal cancer cells. PMID: 28531803 Ref: Effects of 17-allylamino-17-demethoxygeldanamycin on the induction of apoptosis and cell cycle arrest in HCT-116 cells. PMID: 28789442 Ref: Luteolin induces apoptotic cell death via antioxidant activity in human colon cancer cells. PMID: 28791416 Ref: Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene)thiazolidin-2-ylidene)amino) benzenesulfonamides: Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular modelling studies. PMID: 28802125 Ref: Mesua ferrea stem bark extract induces apoptosis and inhibits metastasis in human colorectal carcinoma HCT 116 cells, through modulation of multiple cell signalling pathways. PMID: 28807224 Ref: In vitro anticancer activity of new gold(III) porphyrin complexes in colon cancer cells. PMID: 28923355 Ref: Morin Inhibits Proliferation of SW480 Colorectal Cancer Cells by Inducing Apoptosis Mediated by Reactive Oxygen Species Formation and Uncoupling of Warburg Effect. PMID: 28955240 Ref: Inositol Hexaphosphate Inhibits Proliferation and Induces Apoptosis of Colon Cancer Cells by Suppressing the AKT/mTOR Signaling Pathway. PMID: 28972559 Ref: Knockdown of SLC39A7 inhibits cell growth and induces apoptosis in human colorectal cancer cells. PMID: 28981607 Ref: In vitro investigation of the effect of matrix molecules on the behavior of colon cancer cells under the effect of geldanamycin derivative. PMID: 29034805 Ref: Synergism between alpha-mangostin and TRAIL induces apoptosis in squamous cell carcinoma of the oral cavity through the mitochondrial pathway. PMID: 29039600 Ref: Pien Tze Huang induces apoptosis and inhibits proliferation of 5-fluorouracil-resistant colorectal carcinoma cells via increasing miR-22 expression. PMID: 29042944 Ref: The preclinical analysis of TW-37 as a potential anti-colorectal cancer cell agent. PMID: 29065135 Ref: Grape seed proanthocyanidins induce mitochondrial pathway-mediated apoptosis in human colorectal carcinoma cells. PMID: 29113217 Ref: Establishment of optimal regulatory network of colorectal cancer based on p42.3 protein. PMID: 29551923 |
Ref: Berbamine suppresses cell viability and induces apoptosis in colorectal cancer via activating p53-dependent apoptotic signaling pathway. PMID: 28965196 Ref: Crosstalk between p38 MAPK and caspase-9 regulates mitochondria-mediated apoptosis induced by tetra-alpha-(4-carboxyphenoxy) phthalocyanine zinc photodynamic therapy in LoVo cells. PMID: 29115534 Ref: Zerumbone, a Cyclic Sesquiterpene from Zingiber zerumbet Induces Apoptosis, Cell Cycle Arrest, and Antimigratory Effects in SW480 Colorectal Cancer Cells. PMID: 29276946 Ref: Effect of long non-coding RNA Gas5 on proliferation, migration, invasion and apoptosis of colorectal cancer HT-29 cell line. PMID: 29308053 Ref: Acetaminophen and Metamizole Induce Apoptosis in HT 29 and SW 480 Colon Carcinoma Cell Lines In Vitro. PMID: 29374698 Ref: Vitexin induces apoptosis by suppressing autophagy in multi-drug resistant colorectal cancer cells. PMID: 29423046 Ref: Chemoprevention by Probiotics During 1,2-Dimethylhydrazine-Induced Colon Carcinogenesis in Rats. PMID: 29427224 Ref: Overexpression of Nitrogen Permease Regulator Like-2 (NPRL2) Enhances Sensitivity to Irinotecan (CPT-11) in Colon Cancer Cells by Activating the DNA Damage Checkpoint Pathway. PMID: 29519997 Ref: An Asparagus polysaccharide fraction inhibits MDSCs by inducing apoptosis through toll-like receptor 4. PMID: 29532545 Ref: Wogonoside inhibits cell growth and induces mitochondrial-mediated autophagy-related apoptosis in human colon cancer cells through the PI3K/AKT/mTOR/p70S6K signaling pathway. PMID: 29541215 Ref: Design and synthesis of novel pyrrolo[2,3-a]carbazoles: 7-Chloro-2-oxo-3a-(2'-oxo-2',3'-dihydro-1'H-indol-3'-yl)-2,3,3a,4,5,10-hexahydro- pyrrolo[3,2-a]carbazole-1-carbonitrile as an efficient anticancer agent. PMID: 29597168 Ref: Development of Promising Thiopyrimidine-Based Anti-cancer and Antimicrobial Agents: Synthesis and QSAR Analysis. PMID: 29600761 Ref: The apoptotic effects of Brucea javanica fruit extract against HT29 cells associated with p53 upregulation and inhibition of NF-kappaB translocation. PMID: 29636600 Ref: DK1 Induces Apoptosis via Mitochondria-Dependent Signaling Pathway in Human Colon Carcinoma Cell Lines In Vitro. PMID: 29641445 Ref: The inhibitory effect of Manuka honey on human colon cancer HCT-116 and LoVo cell growth. Part 1: the suppression of cell proliferation, promotion of apoptosis and arrest of the cell cycle. PMID: 29645049 Ref: Resveratrol analogue, (E)-N-(2-(4-methoxystyryl) phenyl) furan-2-carboxamide induces G2/M cell cycle arrest through the activation of p53-p21(CIP1/WAF1) in human colorectal HCT116 cells. PMID: 29754265 Ref: Antitumor, antioxidant and anti-inflammatory activities of kaempferol and its corresponding glycosides and the enzymatic preparation of kaempferol. PMID: 29771951 Ref: Expression Level of Caspase Genes in Colorectal Cancer PMID: 29801534 Ref: Upregulation of let-7f-5p promotes chemotherapeutic resistance in colorectal cancer by directly repressing several pro-apoptotic proteins. PMID: 29805607 Ref: C-glycosyl flavone from Urginea indica inhibits proliferation & angiogenesis & induces apoptosis via cyclin-dependent kinase 6 in human breast, hepatic & colon cancer cell lines. PMID: 29806604 Ref: LncRNA BX357664 inhibits cell proliferation and invasion and promotes cell apoptosis in human colorectal cancer cells. PMID: 29844809 Ref: Dasatinib reduces 5-Fu-triggered apoptosis in colon carcinoma by directly modulating Src-dependent caspase-9 phosphorylation. PMID: 29844931 Ref: Pea lectin inhibits cell growth by inducing apoptosis in SW480 and SW48 cell lines. PMID: 29885391 Ref: Artesunate induces apoptosis and autophagy in HCT116 colon cancer cells, and autophagy inhibition enhances the artesunateinduced apoptosis. PMID: 29901098 Ref: Ellagitannins from Pomegranate Ameliorates 5-Fluorouracil-Induced Intestinal Mucositis in Rats while Enhancing Its Chemotoxicity against HT-29 Colorectal Cancer Cells through Intrinsic Apoptosis Induction. PMID: 29920075 Ref: Shikonin Exerts Cytotoxic Effects in Human Colon Cancers by Inducing Apoptotic Cell Death via the Endoplasmic Reticulum and Mitochondria-Mediated Pathways. PMID: 29925224 Ref: Knockdown of MiR-20a Enhances Sensitivity of Colorectal Cancer Cells to Cisplatin by Increasing ASK1 Expression. PMID: 29940575 Ref: Selective Cu(I) complex with phosphine-peptide (SarGly) conjugate contra breast cancer: Synthesis, spectroscopic characterization and insight into cytotoxic action. PMID: 29945023 Ref: Impairing Powerhouse in Colon Cancer Cells by Hydrazide-Hydrazone-Based Small Molecule. PMID: 30023806 Ref: Suppression of Notch1 and AKT mediated epithelial to mesenchymal transition by Verrucarin J in metastatic colon cancer. PMID: 30038258 Ref: Icariin reduces human colon carcinoma cell growth and metastasis by enhancing p53 activities. PMID: 30088538 Ref: Sorbus commixta water extract induces apoptotic cell death via a ROS-dependent pathway. PMID: 30197667 Ref: Tumor-associated carbonic anhydrase isoform IX and XII inhibitory properties of certain isatin-bearing sulfonamides endowed with in vitro antitumor activity towards colon cancer. PMID: 30219719 Ref: MPT0B169 and MPT0B002, New Tubulin Inhibitors, Induce Growth Inhibition, G2/M Cell Cycle Arrest, and Apoptosis in Human Colorectal Cancer Cells. PMID: 30227438 Ref: Tanshinone IIA reduces SW837 colorectal cancer cell viability via the promotion of mitochondrial fission by activating JNK-Mff signaling pathways. PMID: 30253740 Ref: Cytotoxic effect of methanolic extract, alkaloid and terpenoid fractions of Stachys pilifera against HT-29 cell line. PMID: 30271442 Ref: Possible role of p53/Mieap-regulated mitochondrial quality control as a tumor suppressor in human breast cancer. PMID: 30290054 Ref: alpha-Hederin Arrests Cell Cycle at G2/M Checkpoint and Promotes Mitochondrial Apoptosis by Blocking Nuclear Factor-kappaB Signaling in Colon Cancer Cells. PMID: 30363706 |