Primary Site >> Pancreatic Cancer
Gene >> CASP8
| 1. | |||||||||||
| Journal: | Histopathology. 1998 Nov;33(5):432-9. | ||||||||||
| Title: | Apoptotic index and apoptosis influencing proteins bcl-2, mcl-1, bax and caspases 3, 6 and 8 in pancreatic carcinoma. | ||||||||||
| Author: | Virkajarvi, N|Paakko, P|Soini, Y | ||||||||||
| PMID: | 9839167 | ||||||||||
| 2. | |||||||||||
| Journal: | Oncogene. 2000 Nov 16;19(48):5477-86. | ||||||||||
| Title: | Bcl-XL protects pancreatic adenocarcinoma cells against CD95- and TRAIL-receptor-mediated apoptosis. | ||||||||||
| Author: | Hinz, S|Trauzold, A|Boenicke, L|Sandberg, C|Beckmann, S|Bayer, E|Walczak, H|Kalthoff, H|Ungefroren, H | ||||||||||
| PMID: | 11114725 | ||||||||||
| 3. | |||||||||||
| Journal: | Clin Cancer Res. 2001 Feb;7(2):407-14. | ||||||||||
| Title: | Combination of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and actinomycin D induces apoptosis even in TRAIL-resistant human pancreatic cancer cells. | ||||||||||
| Author: | Matsuzaki, H|Schmied, B M|Ulrich, A|Standop, J|Schneider, M B|Batra, S K|Picha, K S|Pour, P M | ||||||||||
| PMID: | 11234897 | ||||||||||
| 4. | |||||||||||
| Journal: | Anticancer Res. 2001 May-Jun;21(3B):1789-94. | ||||||||||
| Title: | Irofulven (6-hydroxymethylacylfulvene, MGI 114) induces caspase 8 and 9-mediated apoptosis in human pancreatic adenocarcinoma cells. | ||||||||||
| Author: | Wang, W|Waters, S J|MacDonald, J R|Von Hoff, D D|Strodel, W E|Miller, A R | ||||||||||
| PMID: | 11497260 | ||||||||||
| 5. | |||||||||||
| Journal: | Pancreas. 2001 Oct;23(3):251-8. | ||||||||||
| Title: | Tumor necrosis factor-related apoptosis-inducing ligand and its receptor expression and the pathway of apoptosis in human pancreatic cancer. | ||||||||||
| Author: | Satoh, K|Kaneko, K|Hirota, M|Masamune, A|Satoh, A|Shimosegawa, T | ||||||||||
| PMID: | 11590320 | ||||||||||
| 6. | |||||||||||
| Journal: | Oncogene. 2001 Nov 1;20(50):7437-46. | ||||||||||
| Title: | Gene expression profiles of pancreatic cancer and stromal desmoplasia. | ||||||||||
| Author: | Crnogorac-Jurcevic, T|Efthimiou, E|Capelli, P|Blaveri, E|Baron, A|Terris, B|Jones, M|Tyson, K|Bassi, C|Scarpa, A|Lemoine, N R | ||||||||||
| PMID: | 11704875 | ||||||||||
| 7. | |||||||||||
| Journal: | Br J Cancer. 2002 Mar 18;86(6):893-8. | ||||||||||
| Title: | Analysis of the cytochrome c-dependent apoptosis apparatus in cells from human pancreatic carcinoma. | ||||||||||
| Author: | Gerhard, M C|Schmid, R M|Hacker, G | ||||||||||
| PMID: | 11953820 | ||||||||||
| 8. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2002 Jun;49(6):504-10. | ||||||||||
| Title: | Overexpression of Bax sensitizes human pancreatic cancer cells to apoptosis induced by chemotherapeutic agents. | ||||||||||
| Author: | Xu, Zhong-Wei|Friess, Helmut|Buchler, Markus W|Solioz, Marc | ||||||||||
| PMID: | 12107556 | ||||||||||
| 9. | |||||||||||
| Journal: | Surgery. 2002 Aug;132(2):127-34. | ||||||||||
| Title: | Selective targeting of the nuclear factor-kappaB pathway enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated pancreatic cancer cell death. | ||||||||||
| Author: | Thomas, Robert P|Farrow, Buckminster J|Kim, Sunghoon|May, Michael J|Hellmich, Mark R|Evers, B Mark | ||||||||||
| PMID: | 12219002 | ||||||||||
| 10. | |||||||||||
| Journal: | Mol Cancer Ther. 2002 Sep;1(11):929-35. | ||||||||||
| Title: | Lipoxygenase inhibitors attenuate growth of human pancreatic cancer xenografts and induce apoptosis through the mitochondrial pathway. | ||||||||||
| Author: | Tong, Wei-Gang|Ding, Xian-Zhong|Witt, Richard C|Adrian, Thomas E | ||||||||||
| PMID: | 12481414 | ||||||||||
| 11. | |||||||||||
| Journal: | Int J Gastrointest Cancer. 2002;32(1):7-22. | ||||||||||
| Title: | Peroxisome proliferator-activated receptor gamma ligand inhibits cell growth and invasion of human pancreatic cancer cells. | ||||||||||
| Author: | Hashimoto, Koji|Ethridge, Richard T|Evers, B Mark | ||||||||||
| PMID: | 12630765 | ||||||||||
| 12. | |||||||||||
| Journal: | Anticancer Res. 2003 Jan-Feb;23(1A):251-8. | ||||||||||
| Title: | Synergistic cytotoxic effect of TRAIL and gemcitabine in pancreatic cancer cells. | ||||||||||
| Author: | Xu, Zhong-Wei|Kleeff, Jorg|Friess, Helmut|Buchler, Markus W|Solioz, Marc | ||||||||||
| PMID: | 12680221 | ||||||||||
| 13. | |||||||||||
| Journal: | Int J Cancer. 2004 Mar 20;109(2):182-8. | ||||||||||
| Title: | Resistance of pancreatic cancer to gemcitabine treatment is dependent on mitochondria-mediated apoptosis. | ||||||||||
| Author: | Schniewind, Bodo|Christgen, Matthias|Kurdow, Roland|Haye, Sieglinde|Kremer, Bernd|Kalthoff, Holger|Ungefroren, Hendrik | ||||||||||
| PMID: | 14750167 | ||||||||||
| 14. | |||||||||||
| Journal: | Pancreas. 2004 Mar;28(2):153-9. | ||||||||||
| Title: | Activation and role of MAP kinases in 15d-PGJ2-induced apoptosis in the human pancreatic cancer cell line MIA PaCa-2. | ||||||||||
| Author: | Hashimoto, Koji|Farrow, Buckminster J|Evers, B Mark | ||||||||||
| PMID: | 15028947 | ||||||||||
| 15. | |||||||||||
| Journal: | Int J Oncol. 2005 Feb;26(2):537-44. | ||||||||||
| Title: | Adenovirus-mediated gene transfer of caspase-8 sensitizes human adenocarcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand. | ||||||||||
| Author: | Yasui, Hiroshi|Adachi, Masaaki|Hamada, Hirofumi|Imai, Kohzoh | ||||||||||
| PMID: | 15645141 | ||||||||||
| 16. | |||||||||||
| Journal: | J Gastroenterol. 2005 May;40(5):504-10. | ||||||||||
| Title: | Upregulation of BNIP3 by 5-aza-2'-deoxycytidine sensitizes pancreatic cancer cells to hypoxia-mediated cell death. | ||||||||||
| Author: | Abe, Tamaki|Toyota, Minoru|Suzuki, Hiromu|Murai, Masafumi|Akino, Kimishige|Ueno, Masako|Nojima, Masanori|Yawata, Atsushi|Miyakawa, Hiroyuki|Suga, Toshihiro|Ito, Hideto|Endo, Takao|Tokino, Takashi|Hinoda, Yuji|Imai, Kohzoh | ||||||||||
| PMID: | 15942716 | ||||||||||
| 17. | |||||||||||
| Journal: | Cancer Lett. 2005 Sep 28;227(2):193-200. | ||||||||||
| Title: | Gemcitabine-mediated apoptosis is associated with increased CD95 surface expression but is not inhibited by DN-FADD in Colo357 pancreatic cancer cells. | ||||||||||
| Author: | Christgen, Matthias|Schniewind, Bodo|Jueschke, Astrid|Ungefroren, Hendrik|Kalthoff, Holger | ||||||||||
| PMID: | 16112422 | ||||||||||
| 18. | |||||||||||
| Journal: | Int J Oncol. 2005 Nov;27(5):1247-55. | ||||||||||
| Title: | Enhancement of the caspase-independent apoptotic sensitivity of pancreatic cancer cells by DHMEQ, an NF-kappaB inhibitor. | ||||||||||
| Author: | Matsumoto, Gaku|Muta, Mariko|Umezawa, Kazuo|Suzuki, Tomoyoshi|Misumi, Keizo|Tsuruta, Koji|Okamoto, Atsutake|Toi, Masakazu | ||||||||||
| PMID: | 16211219 | ||||||||||
| 19. | |||||||||||
| Journal: | Cancer Res. 2005 Nov 15;65(22):10502-13. | ||||||||||
| Title: | Sensitization for gamma-irradiation-induced apoptosis by second mitochondria-derived activator of caspase. | ||||||||||
| Author: | Giagkousiklidis, Stavros|Vogler, Meike|Westhoff, Mike-Andrew|Kasperczyk, Hubert|Debatin, Klaus-Michael|Fulda, Simone | ||||||||||
| PMID: | 16288043 | ||||||||||
| 20. | |||||||||||
| Journal: | Carcinogenesis. 2006 Apr;27(4):717-28. | ||||||||||
| Title: | 3,3'-diindolylmethane (DIM) and its derivatives induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation of DR5. | ||||||||||
| Author: | Abdelrahim, Maen|Newman, Kristen|Vanderlaag, Kathy|Samudio, Ismael|Safe, Stephen | ||||||||||
| PMID: | 16332727 | ||||||||||
| 21. | |||||||||||
| Journal: | Cancer Res. 2006 Apr 15;66(8):4309-18. | ||||||||||
| Title: | Crosstalk between extrinsic and intrinsic cell death pathways in pancreatic cancer: synergistic action of estrogen metabolite and ligands of death receptor family. | ||||||||||
| Author: | Basu, Aruna|Castle, Valerie P|Bouziane, Mohammed|Bhalla, Kapil|Haldar, Subrata | ||||||||||
| PMID: | 16618756 | ||||||||||
| 22. | |||||||||||
| Journal: | Am J Surg. 2006 Mar;191(3):358-63. | ||||||||||
| Title: | Interferon receptors and the caspase cascade regulate the antitumor effects of interferons on human pancreatic cancer cell lines. | ||||||||||
| Author: | Saidi, Reza F|Williams, Frances|Ng, Jennica|Danquah, Grace|Mittal, Vijay K|ReMine, Stephen G|Jacobs, Michael J | ||||||||||
| PMID: | 16490547 | ||||||||||
| 23. | |||||||||||
| Journal: | J Mol Med (Berl). 2006 May;84(5):405-15. | ||||||||||
| Title: | Mechanism of triptolide-induced apoptosis: Effect on caspase activation and Bid cleavage and essentiality of the hydroxyl group of triptolide. | ||||||||||
| Author: | Wang, Xianxi|Matta, Ranyia|Shen, Gang|Nelin, Leif D|Pei, Dehua|Liu, Yusen | ||||||||||
| PMID: | 16385419 | ||||||||||
| 24. | |||||||||||
| Journal: | Int J Oncol. 2006 Mar;28(3):705-13. | ||||||||||
| Title: | Differential gene expression profiles of radioresistant pancreatic cancer cell lines established by fractionated irradiation. | ||||||||||
| Author: | Ogawa, Kazuhiko|Utsunomiya, Tohru|Mimori, Koshi|Tanaka, Fumiaki|Haraguchi, Naotsugu|Inoue, Hiroshi|Murayama, Sadayuki|Mori, Masaki | ||||||||||
| PMID: | 16465376 | ||||||||||
| 25. | |||||||||||
| Journal: | Cancer. 2007 May 15;109(10):2142-53. | ||||||||||
| Title: | Mechanisms of synthetic serine protease inhibitor (FUT-175)-mediated cell death. | ||||||||||
| Author: | Uwagawa, Tadashi|Li, Zhongkui|Chang, Zhe|Xia, Qianghua|Peng, Bailu|Sclabas, Guido M|Ishiyama, Satoshi|Hung, Mien-Chie|Evans, Douglas B|Abbruzzese, James L|Chiao, Paul J | ||||||||||
| PMID: | 17410536 | ||||||||||
| 26. | |||||||||||
| Journal: | Anticancer Drugs. 2007 Jun;18(5):535-41. | ||||||||||
| Title: | Leukotriene B4 receptor antagonist LY293111 induces S-phase cell cycle arrest and apoptosis in human pancreatic cancer cells. | ||||||||||
| Author: | Tong, Wei-Gang|Ding, Xian-Zhong|Talamonti, Mark S|Bell, Richard H|Adrian, Thomas E | ||||||||||
| PMID: | 17414622 | ||||||||||
| 27. | |||||||||||
| Journal: | J Gastroenterol Hepatol. 2007 May;22(5):738-48. | ||||||||||
| Title: | Combination therapy of poly (ADP-ribose) polymerase inhibitor 3-aminobenzamide and gemcitabine shows strong antitumor activity in pancreatic cancer cells. | ||||||||||
| Author: | Jacob, Dietmar A|Bahra, Marcus|Langrehr, Jan M|Boas-Knoop, Sabine|Stefaniak, Robert|Davis, John|Schumacher, Guido|Lippert, Steffen|Neumann, Ulf P | ||||||||||
| PMID: | 17444865 | ||||||||||
| 28. | |||||||||||
| Journal: | Cell Signal. 2007 Nov;19(11):2237-46. Epub 2007 Jun 21. | ||||||||||
| Title: | Inhibition of RIP and c-FLIP enhances TRAIL-induced apoptosis in pancreatic cancer cells. | ||||||||||
| Author: | Wang, Peng|Zhang, Jing|Bellail, Anita|Jiang, Wen|Hugh, Judith|Kneteman, Norman M|Hao, Chunhai | ||||||||||
| PMID: | 17693058 | ||||||||||
| 29. | |||||||||||
| Journal: | Nat Med. 2007 Sep;13(9):1070-7. | ||||||||||
| Title: | Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL. | ||||||||||
| Author: | Wagner, Klaus W|Punnoose, Elizabeth A|Januario, Thomas|Lawrence, David A|Pitti, Robert M|Lancaster, Kate|Lee, Dori|von Goetz, Melissa|Yee, Sharon Fong|Totpal, Klara|Huw, Ling|Katta, Viswanatham|Cavet, Guy|Hymowitz, Sarah G|Amler, Lukas|Ashkenazi, Avi | ||||||||||
| PMID: | 17767167 | ||||||||||
| 30. | |||||||||||
| Journal: | Clin Cancer Res. 2007 Sep 15;13(18 Pt 2):5535s-5543s. | ||||||||||
| Title: | Combination treatment with TRA-8 anti death receptor 5 antibody and CPT-11 induces tumor regression in an orthotopic model of pancreatic cancer. | ||||||||||
| Author: | DeRosier, Leo Christopher|Buchsbaum, Donald J|Oliver, Patsy G|Huang, Zhi-Qiang|Sellers, Jeffrey C|Grizzle, William E|Wang, Wenquan|Zhou, Tong|Zinn, Kurt R|Long, Joshua W|Vickers, Selwyn M | ||||||||||
| PMID: | 17875786 | ||||||||||
| 31. | |||||||||||
| Journal: | Clin Cancer Res. 2008 May 15;14(10):3230-6. | ||||||||||
| Title: | Functional variants in cell death pathway genes and risk of pancreatic cancer. | ||||||||||
| Author: | Yang, Ming|Sun, Tong|Wang, Li|Yu, Dianke|Zhang, Xuemei|Miao, Xiaoping|Liu, Junniao|Zhao, Dan|Li, Hui|Tan, Wen|Lin, Dongxin | ||||||||||
| PMID: | 18483392 | ||||||||||
| 32. | |||||||||||
| Journal: | World J Gastroenterol. 2008 Dec 21;14(47):7192-8. | ||||||||||
| Title: | Metformin induces apoptosis of pancreatic cancer cells. | ||||||||||
| Author: | Wang, Luo-Wei|Li, Zhao-Shen|Zou, Duo-Wu|Jin, Zhen-Dong|Gao, Jun|Xu, Guo-Ming | ||||||||||
| PMID: | 19084933 | ||||||||||
| 33. | |||||||||||
| Journal: | Int J Oncol. 2008 Oct;33(4):657-63. | ||||||||||
| Title: | Dietary isothiocyanate mediated apoptosis of human cancer cells is associated with Bcl-xL phosphorylation. | ||||||||||
| Author: | Basu, Aruna|Haldar, Subrata | ||||||||||
| PMID: | 18813778 | ||||||||||
| 34. | |||||||||||
| Journal: | Mol Cancer Ther. 2008 Sep;7(9):2633-48. | ||||||||||
| Title: | Mitogen-activated protein kinase kinase 1/2 inhibitors and 17-allylamino-17-demethoxygeldanamycin synergize to kill human gastrointestinal tumor cells in vitro via suppression of c-FLIP-s levels and activation of CD95. | ||||||||||
| Author: | Park, Margaret A|Zhang, Guo|Mitchell, Clint|Rahmani, Mohamed|Hamed, Hossein|Hagan, Michael P|Yacoub, Adly|Curiel, David T|Fisher, Paul B|Grant, Steven|Dent, Paul | ||||||||||
| PMID: | 18790746 | ||||||||||
| 35. | |||||||||||
| Journal: | FASEB J. 2008 Sep;22(9):3358-69. | ||||||||||
| Title: | Human tumor nanoparticles induce apoptosis of pancreatic cancer cells. | ||||||||||
| Author: | Ristorcelli, Elodie|Beraud, Evelyne|Verrando, Patrick|Villard, Claude|Lafitte, Daniel|Sbarra, Veronique|Lombardo, Dominique|Verine, Alain | ||||||||||
| PMID: | 18511551 | ||||||||||
| 36. | |||||||||||
| Journal: | Pancreatology. 2009;9(6):797-809. | ||||||||||
| Title: | Plumbagin, isolated from Plumbago zeylanica, induces cell death through apoptosis in human pancreatic cancer cells. | ||||||||||
| Author: | Chen, Chien-An|Chang, Hen-Hong|Kao, Chung-Yu|Tsai, Tung-Hu|Chen, Yu-Jen | ||||||||||
| PMID: | 20110748 | ||||||||||
| 37. | |||||||||||
| Journal: | Cancer Epidemiol Biomarkers Prev. 2009 Nov;18(11):3044-8. | ||||||||||
| Title: | Association of breast cancer susceptibility variants with risk of pancreatic cancer. | ||||||||||
| Author: | Couch, Fergus J|Wang, Xianshu|McWilliams, Robert R|Bamlet, William R|de Andrade, Mariza|Petersen, Gloria M | ||||||||||
| PMID: | 19843670 | ||||||||||
| 38. | |||||||||||
| Journal: | Mol Pharmacol. 2009 Aug;76(2):327-41. | ||||||||||
| Title: | BCL-2 family inhibitors enhance histone deacetylase inhibitor and sorafenib lethality via autophagy and overcome blockade of the extrinsic pathway to facilitate killing. | ||||||||||
| Author: | Martin, Aditi Pandya|Park, Margaret A|Mitchell, Clint|Walker, Teneille|Rahmani, Mohamed|Thorburn, Andrew|Haussinger, Dieter|Reinehr, Roland|Grant, Steven|Dent, Paul | ||||||||||
| PMID: | 19483105 | ||||||||||
| 39. | |||||||||||
| Journal: | Br J Pharmacol. 2009 Aug;157(7):1175-85. | ||||||||||
| Title: | Combined treatment with denbinobin and Fas ligand has a synergistic cytotoxic effect in human pancreatic adenocarcinoma BxPC-3 cells. | ||||||||||
| Author: | Yang, C R|Guh, J H|Teng, C M|Chen, C C|Chen, P H | ||||||||||
| PMID: | 19466993 | ||||||||||
| 40. | |||||||||||
| Journal: | Clin Cancer Res. 2009 Jan 1;15(1):150-9. | ||||||||||
| Title: | BH3 mimetic obatoclax enhances TRAIL-mediated apoptosis in human pancreatic cancer cells. | ||||||||||
| Author: | Huang, Shengbing|Okumura, Kenji|Sinicrope, Frank A | ||||||||||
| PMID: | 19118042 | ||||||||||
| 41. | |||||||||||
| Journal: | Cancer Res. 2009 Feb 1;69(3):1156-65. | ||||||||||
| Title: | Suppression of cFLIP by lupeol, a dietary triterpene, is sufficient to overcome resistance to TRAIL-mediated apoptosis in chemoresistant human pancreatic cancer cells. | ||||||||||
| Author: | Murtaza, Imtiyaz|Saleem, Mohammad|Adhami, Vaqar Mustafa|Hafeez, Bilal Bin|Mukhtar, Hasan | ||||||||||
| PMID: | 19176377 | ||||||||||
| 42. | |||||||||||
| Journal: | Int J Oncol. 2009 Jan;34(1):281-6. | ||||||||||
| Title: | Combinatorial effect of epigallocatechin-3-gallate and TRAIL on pancreatic cancer cell death. | ||||||||||
| Author: | Basu, Aruna|Haldar, Subrata | ||||||||||
| PMID: | 19082499 | ||||||||||
| 43. | |||||||||||
| Journal: | Pancreas. 2009 Jan;38(1):94-100. | ||||||||||
| Title: | Inhibition of pancreatic cancer cell proliferation by propranolol occurs through apoptosis induction: the study of beta-adrenoceptor antagonist's anticancer effect in pancreatic cancer cell. | ||||||||||
| Author: | Zhang, Dong|Ma, Qingyong|Shen, Sugang|Hu, Hengtong | ||||||||||
| PMID: | 19106745 | ||||||||||
| 44. | |||||||||||
| Journal: | Cancer Res. 2010 May 1;70(9):3718-29. | ||||||||||
| Title: | Adipose-derived mesenchymal stem cells as stable source of tumor necrosis factor-related apoptosis-inducing ligand delivery for cancer therapy. | ||||||||||
| Author: | Grisendi, Giulia|Bussolari, Rita|Cafarelli, Luigi|Petak, Istvan|Rasini, Valeria|Veronesi, Elena|De Santis, Giorgio|Spano, Carlotta|Tagliazzucchi, Mara|Barti-Juhasz, Helga|Scarabelli, Laura|Bambi, Franco|Frassoldati, Antonio|Rossi, Giulio|Casali, Christian | ||||||||||
| PMID: | 20388793 | ||||||||||
| 45. | |||||||||||
| Journal: | Mol Cancer. 2010 Apr 16;9:80. | ||||||||||
| Title: | HDAC2 attenuates TRAIL-induced apoptosis of pancreatic cancer cells. | ||||||||||
| Author: | Schuler, Susanne|Fritsche, Petra|Diersch, Sandra|Arlt, Alexander|Schmid, Roland M|Saur, Dieter|Schneider, Gunter | ||||||||||
| PMID: | 20398369 | ||||||||||
| 46. | |||||||||||
| Journal: | Oncol Rep. 2010 Oct;24(4):843-50. | ||||||||||
| Title: | Anti-tumor effect by inhibition of NF-kappaB activation using nafamostat mesilate for pancreatic cancer in a mouse model. | ||||||||||
| Author: | Furukawa, Kenei|Iida, Tomonori|Shiba, Hiroaki|Fujiwara, Yuki|Uwagawa, Tadashi|Shimada, Yohta|Misawa, Takeyuki|Ohashi, Toya|Yanaga, Katsuhiko | ||||||||||
| PMID: | 20811662 | ||||||||||
| 47. | |||||||||||
| Journal: | Clin Exp Metastasis. 2011 Apr;28(4):367-76. | ||||||||||
| Title: | Transient silencing of galectin-3 expression promotes both in vitro and in vivo drug-induced apoptosis of human pancreatic carcinoma cells. | ||||||||||
| Author: | Kobayashi, Tsutomu|Shimura, Tatsuo|Yajima, Toshiki|Kubo, Norio|Araki, Kenichiro|Wada, Wataru|Tsutsumi, Soichi|Suzuki, Hideki|Kuwano, Hiroyuki|Raz, Avraham | ||||||||||
| PMID: | 21331750 | ||||||||||
| 48. | |||||||||||
| Journal: | Clin Cancer Res. 2011 Sep 15;17(18):5926-34. | ||||||||||
| Title: | Killing of resistant cancer cells with low Bak by a combination of an antimesothelin immunotoxin and a TRAIL Receptor 2 agonist antibody. | ||||||||||
| Author: | Du, Xing|Xiang, Laiman|Mackall, Crystal|Pastan, Ira | ||||||||||
| PMID: | 21813632 | ||||||||||
| 49. | |||||||||||
| Journal: | PLoS One. 2011;6(11):e26390. | ||||||||||
| Title: | A peptide of SPARC interferes with the interaction between caspase8 and Bcl2 to resensitize chemoresistant tumors and enhance their regression in vivo. | ||||||||||
| Author: | Rahman, Mahbuba|Chan, Annie P K|Tang, Michelle|Tai, Isabella T | ||||||||||
| PMID: | 22069448 | ||||||||||
| 50. | |||||||||||
| Journal: | Neoplasia. 2011 Dec;13(12):1162-70. | ||||||||||
| Title: | Requirement of nuclear factor kappaB for Smac mimetic-mediated sensitization of pancreatic carcinoma cells for gemcitabine-induced apoptosis. | ||||||||||
| Author: | Stadel, Dominic|Cristofanon, Silvia|Abhari, Behnaz Ahangarian|Deshayes, Kurt|Zobel, Kerry|Vucic, Domagoj|Debatin, Klaus-Michael|Fulda, Simone | ||||||||||
| PMID: | 22241962 | ||||||||||
| 51. | |||||||||||
| Journal: | Dig Dis Sci. 2012 Aug;57(8):2072-8. | ||||||||||
| Title: | Induction of pancreatic cancer cell apoptosis and enhancement of gemcitabine sensitivity by RAP80 siRNA. | ||||||||||
| Author: | Li, Ya|Gu, Wen-Jun|Liu, Hai-Lin | ||||||||||
| PMID: | 22573342 | ||||||||||
| 52. | |||||||||||
| Journal: | PLoS One. 2012;7(7):e41102. | ||||||||||
| Title: | Glycogen synthase kinase-3 inhibition sensitizes pancreatic cancer cells to TRAIL-induced apoptosis. | ||||||||||
| Author: | Mamaghani, Shadi|Simpson, Craig D|Cao, Pinjiang M|Cheung, May|Chow, Sue|Bandarchi, Bizhan|Schimmer, Aaron D|Hedley, David W | ||||||||||
| PMID: | 22829912 | ||||||||||
| 53. | |||||||||||
| Journal: | Cancer Biol Ther. 2012 Aug;13(10):946-55. | ||||||||||
| Title: | HuR's post-transcriptional regulation of Death Receptor 5 in pancreatic cancer cells. | ||||||||||
| Author: | Pineda, Danielle M|Rittenhouse, David W|Valley, Christopher C|Cozzitorto, Joseph A|Burkhart, Richard A|Leiby, Benjamin|Winter, Jordan M|Weber, Matthew C|Londin, Eric R|Rigoutsos, Isidore|Yeo, Charles J|Gorospe, Myriam|Witkiewicz, Agnieska K|Sachs, Jonatha | ||||||||||
| PMID: | 22785201 | ||||||||||
| 54. | |||||||||||
| Journal: | Cancer Biother Radiopharm. 2012 Sep;27(7):426-33. | ||||||||||
| Title: | The antitumor activity of recombinant antitumor antiviral protein and the associated molecular mechanism in pancreatic tumor cells. | ||||||||||
| Author: | Zeng, Jie|Xiong, Ying|Zhang, Long-Bo|Ruan, Jing-de|Wu, Wei|Sun, Wei-Jia | ||||||||||
| PMID: | 22783925 | ||||||||||
| 55. | |||||||||||
| Journal: | Anticancer Drugs. 2012 Oct;23(9):935-46. | ||||||||||
| Title: | Pancreatic cancer cells retain the epithelial-related phenotype and modify mitotic spindle microtubules after the administration of ukrain in vitro. | ||||||||||
| Author: | Gagliano, Nicoletta|Volpari, Tatiana|Clerici, Marco|Pettinari, Letizia|Barajon, Isabella|Portinaro, Nicola|Colombo, Graziano|Milzani, Aldo|Dalle-Donne, Isabella|Martinelli, Carla | ||||||||||
| PMID: | 22700003 | ||||||||||
| 56. | |||||||||||
| Journal: | Oncol Rep. 2012 Aug;28(2):501-10. | ||||||||||
| Title: | Ursolic acid inhibits growth and induces apoptosis in gemcitabine-resistant human pancreatic cancer via the JNK and PI3K/Akt/NF-kappaB pathways. | ||||||||||
| Author: | Li, Jingjie|Liang, Xiaoyan|Yang, Xing | ||||||||||
| PMID: | 22641480 | ||||||||||
| 57. | |||||||||||
| Journal: | Cancer Lett. 2012 Mar 28;316(2):168-77. | ||||||||||
| Title: | IFN-gamma combined with targeting of XIAP leads to increased apoptosis-sensitisation of TRAIL resistant pancreatic carcinoma cells. | ||||||||||
| Author: | Buneker, Chirlei Klein|Yu, Rui|Deedigan, Laura|Mohr, Andrea|Zwacka, Ralf Michael | ||||||||||
| PMID: | 22104728 | ||||||||||
| 58. | |||||||||||
| Journal: | Pancreas. 2013 Oct;42(7):1114-9. | ||||||||||
| Title: | Absence of FLICE-inhibitory protein is a novel independent prognostic marker for very short survival in pancreatic ductal adenocarcinoma. | ||||||||||
| Author: | Schmid, Sandra J|Glatzel, Marie-Charlotte|Welke, Claudia|Kornmann, Marko|Kleger, Alexander|Barth, Thomas F E|Fulda, Simone|Lennerz, Jochen K|Moller, Peter | ||||||||||
| PMID: | 24005232 | ||||||||||
| 59. | |||||||||||
| Journal: | Photodiagnosis Photodyn Ther. 2013 Sep;10(3):244-251. | ||||||||||
| Title: | Effect of Photofrin-mediated photocytotoxicity on a panel of human pancreatic cancer cells. | ||||||||||
| Author: | Wang, Luo-Wei|Huang, Zheng|Lin, Han|Li, Zhao-Shen|Hetzel, Fred|Liu Md, Bolin | ||||||||||
| PMID: | 23993850 | ||||||||||
| 60. | |||||||||||
| Journal: | Clin Cancer Res. 2013 Sep 1;19(17):4750-9. | ||||||||||
| Title: | PARP-1 regulates resistance of pancreatic cancer to TRAIL therapy. | ||||||||||
| Author: | Yuan, Kaiyu|Sun, Yong|Zhou, Tong|McDonald, Jay|Chen, Yabing | ||||||||||
| PMID: | 23833311 | ||||||||||
| 61. | |||||||||||
| Journal: | J Cell Biochem. 2013 Dec;114(12):2654-65. | ||||||||||
| Title: | Upregulation of extrinsic apoptotic pathway in curcumin-mediated antiproliferative effect on human pancreatic carcinogenesis. | ||||||||||
| Author: | Youns, Mahmoud|Fathy, Gihan Mahmoud | ||||||||||
| PMID: | 23794119 | ||||||||||
| 62. | |||||||||||
| Journal: | World J Gastroenterol. 2013 Mar 14;19(10):1582-92. | ||||||||||
| Title: | Effects of ginsenoside Rh2 on growth and migration of pancreatic cancer cells. | ||||||||||
| Author: | Tang, Xi-Ping|Tang, Guo-Du|Fang, Chun-Yun|Liang, Zhi-Hai|Zhang, Lu-Yi | ||||||||||
| PMID: | 23538603 | ||||||||||
| 63. | |||||||||||
| Journal: | Cancer Lett. 2013 Jun 1;333(1):89-95. | ||||||||||
| Title: | Combination chemotherapy of serine protease inhibitor nafamostat mesilate with oxaliplatin targeting NF-kappaB activation for pancreatic cancer. | ||||||||||
| Author: | Gocho, Takeshi|Uwagawa, Tadashi|Furukawa, Kenei|Haruki, Koichiro|Fujiwara, Yuki|Iwase, Ryota|Misawa, Takeyuki|Ohashi, Toya|Yanaga, Katsuhiko | ||||||||||
| PMID: | 23348695 | ||||||||||
| 64. | |||||||||||
| Journal: | Int J Mol Med. 2013 Jul;32(1):85-92. | ||||||||||
| Title: | Sann-Joong-Kuey-Jian-Tang decreases the protein expression of Mcl1 and TCTP and increases that of TNF-alpha and Bax in BxPC3 pancreatic carcinoma cells. | ||||||||||
| Author: | Chien, Su-Yu|Kuo, Shou-Jen|Chen, Dar-Ren|Su, Chin-Cheng | ||||||||||
| PMID: | 23652631 | ||||||||||
| 65. | |||||||||||
| Journal: | Mol Pharmacol. 2014 Mar;85(3):408-19. | ||||||||||
| Title: | Phosphodiesterase 5 inhibitors enhance chemotherapy killing in gastrointestinal/genitourinary cancer cells. | ||||||||||
| Author: | Booth, Laurence|Roberts, Jane L|Cruickshanks, Nichola|Conley, Adam|Durrant, David E|Das, Anindita|Fisher, Paul B|Kukreja, Rakesh C|Grant, Steven|Poklepovic, Andrew|Dent, Paul | ||||||||||
| PMID: | 24353313 | ||||||||||
| 66. | |||||||||||
| Journal: | Cancer Lett. 2014 Jun 28;348(1-2):156-66. | ||||||||||
| Title: | Triptolide sensitizes pancreatic cancer cells to TRAIL-induced activation of the death receptor pathway. | ||||||||||
| Author: | Chen, Zhiyu|Sangwan, Veena|Banerjee, Sulagna|Chugh, Rohit|Dudeja, Vikas|Vickers, Selwyn M|Saluja, Ashok K | ||||||||||
| PMID: | 24662747 | ||||||||||
| 67. | |||||||||||
| Journal: | Biotechnol J. 2014 May;9(5):652-63. | ||||||||||
| Title: | Knockdown of ribosomal protein L39 by RNA interference inhibits the growth of human pancreatic cancer cells in vitro and in vivo. | ||||||||||
| Author: | Li, Chaodong|Chen, Daijie|Luo, Minyu|Ge, Mei|Zhu, Jianwei | ||||||||||
| PMID: | 24799381 | ||||||||||
| 68. | |||||||||||
| Journal: | MAbs. 2014;6(6):1560-70. | ||||||||||
| Title: | Multivalent nanobodies targeting death receptor 5 elicit superior tumor cell killing through efficient caspase induction. | ||||||||||
| Author: | Huet, Heather A|Growney, Joseph D|Johnson, Jennifer A|Li, Jing|Bilic, Sanela|Ostrom, Lance|Zafari, Mohammad|Kowal, Colleen|Yang, Guizhi|Royo, Axelle|Jensen, Michael|Dombrecht, Bruno|Meerschaert, Kris R A|Kolkman, Joost A|Cromie, Karen D|Mosher, Rebecca|Ga | ||||||||||
| PMID: | 25484045 | ||||||||||
| 69. | |||||||||||
| Journal: | Apoptosis. 2015 Dec;20(12):1587-98. | ||||||||||
| Title: | Replication-competent adenoviruses with the type 35-derived fiber-knob region achieve reactive oxygen species-dependent cytotoxicity and produce greater toxicity than those with the type 5-derived region in pancreatic carcinoma. | ||||||||||
| Author: | Yamauchi, Suguru|Kawamura, Kiyoko|Okamoto, Shinya|Morinaga, Takao|Jiang, Yuanyuan|Shingyoji, Masato|Sekine, Ikuo|Kubo, Shuji|Tada, Yuji|Tatsumi, Koichiro|Shimada, Hideaki|Hiroshima, Kenzo|Tagawa, Masatoshi | ||||||||||
| PMID: | 26373551 | ||||||||||
| 70. | |||||||||||
| Journal: | Oncotarget. 2015 Sep 22;6(28):25308-19. | ||||||||||
| Title: | Calmodulin antagonists promote TRA-8 therapy of resistant pancreatic cancer. | ||||||||||
| Author: | Yuan, Kaiyu|Yong, Sun|Xu, Fei|Zhou, Tong|McDonald, Jay M|Chen, Yabing | ||||||||||
| PMID: | 26320171 | ||||||||||
| 71. | |||||||||||
| Journal: | Mol Cancer Res. 2015 Aug;13(8):1174-84. | ||||||||||
| Title: | PTK6 Potentiates Gemcitabine-Induced Apoptosis by Prolonging S-phase and Enhancing DNA Damage in Pancreatic Cancer. | ||||||||||
| Author: | Ono, Hiroaki|Basson, Marc D|Ito, Hiromichi | ||||||||||
| PMID: | 26013168 | ||||||||||
| 72. | |||||||||||
| Journal: | J Cell Mol Med. 2015 Feb;19(2):340-50. | ||||||||||
| Title: | Overexpression of heat shock protein 27 (HSP27) increases gemcitabine sensitivity in pancreatic cancer cells through S-phase arrest and apoptosis. | ||||||||||
| Author: | Guo, Yang|Ziesch, Andreas|Hocke, Sandra|Kampmann, Eric|Ochs, Stephanie|De Toni, Enrico N|Goke, Burkhard|Gallmeier, Eike | ||||||||||
| PMID: | 25331547 | ||||||||||
| 73. | |||||||||||
| Journal: | Gene. 2016 Jan 15;576(1 Pt 3):476-82. | ||||||||||
| Title: | Ferulic acid decreases cell viability and colony formation while inhibiting migration of MIA PaCa-2 human pancreatic cancer cells in vitro. | ||||||||||
| Author: | Fahrioglu, Umut|Dodurga, Yavuz|Elmas, Levent|Secme, Mucahit | ||||||||||
| PMID: | 26516023 | ||||||||||
| 74. | |||||||||||
| Journal: | Oncol Lett. 2016 Mar;11(3):1879-1884. | ||||||||||
| Title: | Reduced expression of caspase-8 and cleaved caspase-3 in pancreatic ductal adenocarcinoma cells. | ||||||||||
| Author: | Jakubowska, Katarzyna|Guzinska-Ustymowicz, Katarzyna|Famulski, Waldemar|Cepowicz, Dariusz|Jagodzinska, Dorota|Pryczynicz, Anna | ||||||||||
| PMID: | 26998093 | ||||||||||
| 75. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2016 Aug 5;476(4):260-266. | ||||||||||
| Title: | The preclinical evaluation of TIC10/ONC201 as an anti-pancreatic cancer agent. | ||||||||||
| Author: | Zhang, Qiangbo|Wang, Hong|Ran, Lin|Zhang, Zongli|Jiang, Runde | ||||||||||
| PMID: | 27233611 | ||||||||||
| 76. | |||||||||||
| Journal: | PLoS One. 2017 Oct 16;12(10):e0186490. | ||||||||||
| Title: | Inhibition of CUG-binding protein 1 and activation of caspases are critically involved in piperazine derivative BK10007S induced apoptosis in hepatocellular carcinoma cells. | ||||||||||
| Author: | Kim, Ju-Ha|Kwon, Hee Young|Ryu, Dong Hoon|Nam, Min-Ho|Shim, Bum Sang|Kim, Jin Han|Lee, Jae Yeol|Kim, Sung-Hoon | ||||||||||
| PMID: | 29036189 | ||||||||||
| 77. | |||||||||||
| Journal: | Biochim Biophys Acta Mol Cell Res. 2018 Mar;1865(3):522-531. | ||||||||||
| Title: | TRAIL induces apoptosis but not necroptosis in colorectal and pancreatic cancer cells preferentially via the TRAIL-R2/DR5 receptor. | ||||||||||
| Author: | Nahacka, Zuzana|Svadlenka, Jan|Peterka, Martin|Ksandrova, Marie|Benesova, Simona|Neuzil, Jiri|Andera, Ladislav | ||||||||||
| PMID: | 29278689 | ||||||||||
| 78. | |||||||||||
| Journal: | Oncol Lett. 2018 Jul;16(1):769-774. | ||||||||||
| Title: | IL-33 notably inhibits the growth of colon cancer cells. | ||||||||||
| Author: | Chen, Xuhui|Lu, Kuanchang|Timko, Noah J|Weir, Dylan M|Zhu, Ziwen|Qin, Chenglu|Mann, Jeffery D|Bai, Qian|Xiao, Huaping|Nicholl, Michael B|Wakefield, Mark R|Fang, Yujiang | ||||||||||
| PMID: | 29963144 | ||||||||||
| 79. | |||||||||||
| Journal: | Onco Targets Ther. 2018 Aug 10;11:4723-4732. | ||||||||||
| Title: | Enhanced anticancer effects of low-dose curcumin with non-invasive pulsed electric field on PANC-1 cells. | ||||||||||
| Author: | Lu, Chueh-Hsuan|Lin, Shu-Hui|Hsieh, Chih-Hsiung|Chen, Wei-Ting|Chao, Chih-Yu | ||||||||||
| PMID: | 30127620 | ||||||||||
| 80. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2018 Aug 24. pii: 10.1007/s00280-018-3658-9. | ||||||||||
| Title: | A novel TRAIL mutant-TRAIL-Mu3 enhances the antitumor effects by the increased affinity and the up-expression of DR5 in pancreatic cancer. | ||||||||||
| Author: | Huang, Min|Zhu, Hong|Yi, Cheng|Yan, Juan|Wei, Lijia|Yang, Xi|Chen, Shouchun|Huang, Ying | ||||||||||
| PMID: | 30167846 | ||||||||||
| 81. | |||||||||||
| Journal: | J Interferon Cytokine Res. 2018 Sep;38(9):413-422. | ||||||||||
| Title: | Interferon Gamma Inhibits CXCL8-Induced Proliferation and Migration of Pancreatic Cancer BxPC-3 Cell Line via a RhoGDI2/Rac1/NF-kappaB Signaling Pathway. | ||||||||||
| Author: | Zhang, Mingjie|Ding, Guoping|Zhou, Liangjing|Shen, Tao|Xu, Xiaodong|Zhao, Ting|Jia, Shengnan|Cao, LiPing | ||||||||||
| PMID: | 30192158 | ||||||||||