Primary Site >> Liver Cancer

Gene >> CASP8

Journal: Cancer Lett. 1998 Dec 25;134(2):155-62.
Title: Expression of Fas-related genes in human hepatocellular carcinomas.
Author: Shin, E C|Shin, J S|Park, J H|Kim, J J|Kim, H|Kim, S J
PMID: 10025875
Journal: BMC Cancer. 2002 Nov 15;2:29. Epub 2002 Nov 15.
Title: Methylation profiling of twenty promoter-CpG islands of genes which may contribute to hepatocellular carcinogenesis.
Author: Yu, Jian|Ni, Min|Xu, Jian|Zhang, Hongyu|Gao, Baomei|Gu, Jianren|Chen, Jianguo|Zhang, Lisheng|Wu, Mengchao|Zhen, Sushen|Zhu, Jingde
PMID: 12433278
Journal: EMBO J. 2003 May 1;22(9):2104-16.
Title: Pro-apoptotic function of HBV X protein is mediated by interaction with c-FLIP and enhancement of death-inducing signal.
Author: Kim, Kyun-Hwan|Seong, Baik L
PMID: 12727877
Journal: J Biol Chem. 2003 Jul 25;278(30):27593-604.
Title: The human caspase-8 promoter sustains basal activity through SP1 and ETS-like transcription factors and can be up-regulated by a p53-dependent mechanism.
Author: Liedtke, Christian|Groger, Nadine|Manns, Michael P|Trautwein, Christian
PMID: 12748179
Journal: Lab Invest. 2003 Jul;83(7):1033-43.
Title: Cellular FLICE/caspase-8-inhibitory protein as a principal regulator of cell death and survival in human hepatocellular carcinoma.
Author: Okano, Hiroshi|Shiraki, Katsuya|Inoue, Hidekazu|Kawakita, Tomoyuki|Yamanaka, Takenari|Deguchi, Masatoshi|Sugimoto, Kazushi|Sakai, Takahisa|Ohmori, Shigeru|Fujikawa, Katsuhiko|Murata, Kazumoto|Nakano, Takeshi
PMID: 12861043
Journal: Oncogene. 2005 Jan 6;24(1):141-7.
Title: Caspase-8 gene is frequently inactivated by the frameshift somatic mutation 1225_1226delTG in hepatocellular carcinomas.
Author: Soung, Young Hwa|Lee, Jong Woo|Kim, Su Young|Sung, Yong Jik|Park, Won Sang|Nam, Suk Woo|Kim, Sang Ho|Lee, Jung Young|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 15531912
Journal: J Virol. 2006 May;80(9):4372-9.
Title: Hepatitis C virus core protein inhibits tumor necrosis factor alpha-mediated apoptosis by a protective effect involving cellular FLICE inhibitory protein.
Author: Saito, Kousuke|Meyer, Keith|Warner, Rebecca|Basu, Arnab|Ray, Ratna B|Ray, Ranjit
PMID: 16611896
Journal: Biochim Biophys Acta. 2006 Aug;1763(8):844-53.
Title: Adenovirus-mediated transfection of caspase-8 sensitizes hepatocellular carcinoma to TRAIL- and chemotherapeutic agent-induced cell death.
Author: Yamaguchi, Yumi|Shiraki, Katsuya|Fuke, Hiroyuki|Inoue, Tomoko|Miyashita, Kazumi|Yamanaka, Yutaka|Nakano, Takeshi
PMID: 16750275
Journal: Hepatology. 2008 Mar;47(3):908-18.
Title: Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma.
Author: Nishida, Naoshi|Nagasaka, Takeshi|Nishimura, Takafumi|Ikai, Iwao|Boland, C Richard|Goel, Ajay
PMID: 18161048
Journal: Zhonghua Wai Ke Za Zhi. 2008 Jul 1;46(13):1018-21.
Title: [Analysis of apoptosis-related gene expression in different serum level of insulin-like growth factor-1 in mice breast cancer tissue].
Author: Tang, Hong-Bo|Ye, Zi-Rong|Ren, Yu-Ping|Zhang, Shan|Chen, Guo-Qing|Wu, Yi-Ping
PMID: 19035207
Journal: Gastroenterology. 2011 Dec;141(6):2176-87.
Title: Loss of caspase-8 protects mice against inflammation-related hepatocarcinogenesis but induces non-apoptotic liver injury.
Author: Liedtke, Christian|Bangen, Jorg-Martin|Freimuth, Julia|Beraza, Naiara|Lambertz, Daniela|Cubero, Francisco J|Hatting, Maximilian|Karlmark, Karlin R|Streetz, Konrad L|Krombach, Gabriele A|Tacke, Frank|Gassler, Nikolaus|Riethmacher, Dieter|Trautwein, Christi
PMID: 21878202
Journal: Anticancer Res. 2011 Apr;31(4):1173-80.
Title: Pigment epithelial-derived factor inhibits c-FLIP expression and assists ciglitazone-induced apoptosis in hepatocellular carcinoma.
Author: Lai, Li-Ju|Ho, Tsung-Chuan
PMID: 21508362
Journal: Mol Cell Biochem. 2011 Jul;353(1-2):151-7.
Title: Alterations in the expression of genes related to NF-kappaB signaling in liver and kidney of CuZnSOD-deficient mice.
Author: Brzoska, Kamil|Sochanowicz, Barbara|Siomek, Agnieszka|Olinski, Ryszard|Kruszewski, Marcin
PMID: 21472504
Journal: Pharmacology. 2013;91(5-6):339-45.
Title: 1-[2-(2-Methoxyphenylamino)ethylamino]-3-(naphthalene-1-yloxy)propan-2-ol as a potential anticancer drug.
Author: Kanno, Takeshi|Tanaka, Akito|Shimizu, Tadashi|Nakano, Takashi|Nishizaki, Tomoyuki
PMID: 23817168
Journal: Mol Med Rep. 2015 Jan;11(1):203-11.
Title: Rocaglamide overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells by attenuating the inhibition of caspase-8 through cellular FLICE-like-inhibitory protein downregulation.
Author: Luan, Zhou|He, Ying|He, Fan|Chen, Zhishui
PMID: 25333816
Journal: Cell Death Discov. 2016 Oct 3;2:16065.
Title: Simultaneous induction of apoptosis and necroptosis by Tanshinone IIA in human hepatocellular carcinoma HepG2 cells.
Author: Lin, C-Y|Chang, T-W|Hsieh, W-H|Hung, M-C|Lin, I-H|Lai, S-C|Tzeng, Y-J
PMID: 27752362
Journal: Gastroenterol Hepatol Bed Bench. 2016 Dec;9(Suppl1):S14-S22.
Title: Evaluation of liver cirrhosis and hepatocellular carcinoma using Protein-Protein Interaction Networks.
Author: Ehsani Ardakani, Mohammad Javad|Safaei, Akram|Arefi Oskouie, Afsaneh|Haghparast, Hesam|Haghazali, Mehrdad|Mohaghegh Shalmani, Hamid|Peyvandi, Hassan|Naderi, Nosratollah|Zali, Mohammad Reza
PMID: 28224023
Journal: Basic Clin Pharmacol Toxicol. 2017 Oct;121(4):334-341.
Title: Cis-Nerolidol Induces Endoplasmic Reticulum Stress and Cell Death in Human Hepatocellular Carcinoma Cells through Extensive CYP2C19 and CYP1A2 Oxidation.
Author: Biazi, Bruna Isabela|Zanetti, Thalita Alves|Baranoski, Adrivanio|Corveloni, Amanda Cristina|Mantovani, Mario Sergio
PMID: 28256105
Journal: PLoS One. 2017 Apr 28;12(4):e0176802.
Title: Caspase polymorphisms and prognosis of hepatocellular carcinoma.
Author: Zhang, Song|Xiao, Qianyi|Shi, Zhuqing|Yu, Guopeng|Ma, Xiao-Pin|Chen, Haitao|Zhang, Pengyin|Shen, Suqin|Sai-Yin, He-Xi Ge|Chen, Tao-Yang|Lu, Pei-Xin|Wang, Neng-Jin|Ren, Weihua|Huang, Peng|Xie, Jun|Conran, Carly|Zheng, S Lilly|Yu, Long|Xu, Jianfeng|Jiang, D
PMID: 28453560
Journal: Eur Rev Med Pharmacol Sci. 2017 May;21(9):2087-2097.
Title: Targeting of miR-20a against CFLAR to potentiate TRAIL-induced apoptotic sensitivity in HepG2 cells.
Author: Wang, Y|Zhao, Y-R|Zhang, A-Y|Ma, J|Wang, Z-Z|Zhang, X
PMID: 28537677
Journal: Apoptosis. 2017 Aug;22(8):1035-1047.
Title: Genetic variants in cell death pathway genes and HBV-related hepatocellular carcinoma among a Chinese Han population.
Author: Liu, Fei|Li, Fuqiang|Luo, Limei|Yang, Hanteng|Wei, Yonggang|Wang, Wentao|Yan, Lvnan|Wen, Tianfu|Yang, Jiayin|Li, Bo
PMID: 28643196
Journal: Int J Oncol. 2018 Aug;53(2):771-780.
Title: miRNA expression profiling regulates necroptotic cell death in hepatocellular carcinoma.
Author: Visalli, Maria|Bartolotta, Marcello|Polito, Francesca|Oteri, Rosaria|Barbera, Adalberto|Arrigo, Roberto|Di Giorgio, Rosa Maria|Navarra, Giuseppe|Aguennouz, M'hammed
PMID: 29845207
Journal: Cell Physiol Biochem. 2018;48(2):540-555.
Title: LncRNA NEAT1 Promotes Deterioration of Hepatocellular Carcinoma Based on In Vitro Experiments, Data Mining, and RT-qPCR Analysis.
Author: Ling, Zhi-An|Xiong, Dan-Dan|Meng, Rong-Mei|Cen, Jie-Mei|Zhao, Na|Chen, Gang|Li, Ruo-Lin|Dang, Yi-Wu
PMID: 30021196
Journal: J Virol. 2018 Sep 12. pii: JVI.01273-18.
Title: Hepatitis B spliced protein (HBSP) suppresses Fas-mediated hepatocyte apoptosis via activation of PI3K/Akt signaling.
Author: Wu, Shu-Xiang|Chen, Wan-Nan|Jing, Zhen-Tang|Liu, Wei|Lin, Xin-Jian|Lin, Xu
PMID: 30209179