Primary Site >> Liver Cancer

Gene >> CASP8

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Ref: Expression of Fas-related genes in human hepatocellular carcinomas.
PMID: 10025875
Ref: Methylation profiling of twenty promoter-CpG islands of genes which may contribute to hepatocellular carcinogenesis.
PMID: 12433278
Ref: Pro-apoptotic function of HBV X protein is mediated by interaction with c-FLIP and enhancement of death-inducing signal.
PMID: 12727877
Ref: The human caspase-8 promoter sustains basal activity through SP1 and ETS-like transcription factors and can be up-regulated by a p53-dependent mechanism.
PMID: 12748179
Ref: Cellular FLICE/caspase-8-inhibitory protein as a principal regulator of cell death and survival in human hepatocellular carcinoma.
PMID: 12861043
Ref: Caspase-8 gene is frequently inactivated by the frameshift somatic mutation 1225_1226delTG in hepatocellular carcinomas.
PMID: 15531912
Ref: Hepatitis C virus core protein inhibits tumor necrosis factor alpha-mediated apoptosis by a protective effect involving cellular FLICE inhibitory protein.
PMID: 16611896
Ref: Adenovirus-mediated transfection of caspase-8 sensitizes hepatocellular carcinoma to TRAIL- and chemotherapeutic agent-induced cell death.
PMID: 16750275
Ref: Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma.
PMID: 18161048
Ref: [Analysis of apoptosis-related gene expression in different serum level of insulin-like growth factor-1 in mice breast cancer tissue].
PMID: 19035207
Ref: Alterations in the expression of genes related to NF-kappaB signaling in liver and kidney of CuZnSOD-deficient mice.
PMID: 21472504
Ref: Pigment epithelial-derived factor inhibits c-FLIP expression and assists ciglitazone-induced apoptosis in hepatocellular carcinoma.
PMID: 21508362
Ref: Loss of caspase-8 protects mice against inflammation-related hepatocarcinogenesis but induces non-apoptotic liver injury.
PMID: 21878202
Ref: 1-[2-(2-Methoxyphenylamino)ethylamino]-3-(naphthalene-1-yloxy)propan-2-ol as a potential anticancer drug.
PMID: 23817168
Ref: Rocaglamide overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells by attenuating the inhibition of caspase-8 through cellular FLICE-like-inhibitory protein downregulation.
PMID: 25333816
Ref: Simultaneous induction of apoptosis and necroptosis by Tanshinone IIA in human hepatocellular carcinoma HepG2 cells.
PMID: 27752362
Ref: Evaluation of liver cirrhosis and hepatocellular carcinoma using Protein-Protein Interaction Networks.
PMID: 28224023
Ref: Cis-Nerolidol Induces Endoplasmic Reticulum Stress and Cell Death in Human Hepatocellular Carcinoma Cells through Extensive CYP2C19 and CYP1A2 Oxidation.
PMID: 28256105
Ref: Caspase polymorphisms and prognosis of hepatocellular carcinoma.
PMID: 28453560
Ref: Targeting of miR-20a against CFLAR to potentiate TRAIL-induced apoptotic sensitivity in HepG2 cells.
PMID: 28537677
Ref: Genetic variants in cell death pathway genes and HBV-related hepatocellular carcinoma among a Chinese Han population.
PMID: 28643196
Ref: miRNA expression profiling regulates necroptotic cell death in hepatocellular carcinoma.
PMID: 29845207
Ref: LncRNA NEAT1 Promotes Deterioration of Hepatocellular Carcinoma Based on In Vitro Experiments, Data Mining, and RT-qPCR Analysis.
PMID: 30021196
Ref: Hepatitis B spliced protein (HBSP) suppresses Fas-mediated hepatocyte apoptosis via activation of PI3K/Akt signaling.
PMID: 30209179