Primary Site >> Colorectal Cancer

Gene >> CASP8

Journal: Cell Death Differ. 1998 May;5(5):450-7.
Title: Expression of genes that regulate Fas signalling and Fas-mediated apoptosis in colon carcinoma cells.
Author: Tillman, D M|Harwood, F G|Gibson, A A|Houghton, J A
PMID: 10200495
Journal: J Biol Chem. 1999 Mar 19;274(12):7987-92.
Title: Fas ligand-independent, FADD-mediated activation of the Fas death pathway by anticancer drugs.
Author: Micheau, O|Solary, E|Hammann, A|Dimanche-Boitrel, M T
PMID: 10075697
Journal: Biochem Biophys Res Commun. 2000 Mar 5;269(1):179-90.
Title: p21(WAF1/CIP1) inhibits initiator caspase cleavage by TRAIL death receptor DR4.
Author: Xu, S Q|El-Deiry, W S
PMID: 10694497
Journal: Biol Pharm Bull. 2000 Apr;23(4):420-6.
Title: Activation of NF-kappaB determines the sensitivity of human colon cancer cells to TNFalpha-induced apoptosis.
Author: Han, S Y|Choung, S Y|Paik, I S|Kang, H J|Choi, Y H|Kim, S J|Lee, M O
PMID: 10784420
Journal: Br J Cancer. 2000 Jun;82(12):1991-9.
Title: Induction of apoptosis and activation of the caspase cascade by anti-EGF receptor monoclonal antibodies in DiFi human colon cancer cells do not involve the c-jun N-terminal kinase activity.
Author: Liu, B|Fang, M|Schmidt, M|Lu, Y|Mendelsohn, J|Fan, Z
PMID: 10864208
Journal: Cancer Res. 2000 Aug 1;60(15):4270-6.
Title: Characterization of bile salt-induced apoptosis in colon cancer cell lines.
Author: Schlottman, K|Wachs, F P|Krieg, R C|Kullmann, F|Scholmerich, J|Rogler, G
PMID: 10945641
Journal: Biochem Pharmacol. 2000 Dec 1;60(11):1579-84.
Title: Caspase-8 activation independent of CD95/CD95-L interaction during paclitaxel-induced apoptosis in human colon cancer cells (HT29-D4).
Author: Goncalves, A|Braguer, D|Carles, G|Andre, N|Prevot, C|Briand, C
PMID: 11077039
Journal: Cancer Res. 2000 Nov 15;60(22):6259-65.
Title: The caspase 9 inhibitor Z-LEHD-FMK protects human liver cells while permitting death of cancer cells exposed to tumor necrosis factor-related apoptosis-inducing ligand.
Author: Ozoren, N|Kim, K|Burns, T F|Dicker, D T|Moscioni, A D|El-Deiry, W S
PMID: 11103780
Journal: FASEB J. 2001 Feb;15(2):362-72.
Title: PECAM-1 shedding during apoptosis generates a membrane-anchored truncated molecule with unique signaling characteristics.
Author: Ilan, N|Mohsenin, A|Cheung, L|Madri, J A
PMID: 11156952
Journal: Cancer Res. 2001 Feb 15;61(4):1645-51.
Title: Anticancer agents sensitize tumor cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis.
Author: Lacour, S|Hammann, A|Wotawa, A|Corcos, L|Solary, E|Dimanche-Boitrel, M T
PMID: 11245478
Journal: Clin Cancer Res. 2001 Apr;7(4):1010-6.
Title: Induction of apoptosis in colon cancer cells by cyclooxygenase-2 inhibitor NS398 through a cytochrome c-dependent pathway.
Author: Li, M|Wu, X|Xu, X C
PMID: 11309352
Journal: J Gastrointest Surg. 2001 Jan-Feb;5(1):56-65.
Title: Sensitization of human colon cancer cells to TRAIL-mediated apoptosis.
Author: Hernandez, A|Wang, Q D|Schwartz, S A|Evers, B M
PMID: 11309649
Journal: Oncogene. 2001 Feb 1;20(5):571-80.
Title: p53 upregulates cFLIP, inhibits transcription of NF-kappaB-regulated genes and induces caspase-8-independent cell death in DLD-1 cells.
Author: Bartke, T|Siegmund, D|Peters, N|Reichwein, M|Henkler, F|Scheurich, P|Wajant, H
PMID: 11313989
Journal: Hum Pathol. 2001 May;32(5):461-7.
Title: Caspase 7 downregulation as an immunohistochemical marker of colonic carcinoma.
Author: Palmerini, F|Devilard, E|Jarry, A|Birg, F|Xerri, L
PMID: 11381362
Journal: Oncogene. 2001 Jun 21;20(28):3726-34.
Title: The monoclonal antibody 225 activates caspase-8 and induces apoptosis through a tumor necrosis factor receptor family-independent pathway.
Author: Liu, B|Fan, Z
PMID: 11439335
Journal: J Biol Chem. 2001 Oct 19;276(42):38748-54. Epub 2001 Aug 20.
Title: A Fas-associated death domain protein-dependent mechanism mediates the apoptotic action of non-steroidal anti-inflammatory drugs in the human leukemic Jurkat cell line.
Author: Han, Z|Pantazis, P|Wyche, J H|Kouttab, N|Kidd, V J|Hendrickson, E A
PMID: 11514566
Journal: Cancer Res. 2001 Oct 15;61(20):7585-93.
Title: Profiling of cancer cells using protein microarrays: discovery of novel radiation-regulated proteins.
Author: Sreekumar, A|Nyati, M K|Varambally, S|Barrette, T R|Ghosh, D|Lawrence, T S|Chinnaiyan, A M
PMID: 11606398
Journal: Mol Carcinog. 2001 Oct;32(2):73-83.
Title: Molecular mechanisms of apoptosis induced by magnolol in colon and liver cancer cells.
Author: Lin, S Y|Chang, Y T|Liu, J D|Yu, C H|Ho, Y S|Lee, Y H|Lee, W S
PMID: 11746819
Journal: Anticancer Res. 2001 Nov-Dec;21(6A):3733-8.
Title: Interferon-gamma modulates TRAIL-mediated apoptosis in human colon carcinoma cells.
Author: Langaas, V|Shahzidi, S|Johnsen, J I|Smedsrod, B|Sveinbjornsson, B
PMID: 11911240
Journal: Oncogene. 2002 Jan 17;21(3):337-46.
Title: Low glucose-enhanced TRAIL cytotoxicity is mediated through the ceramide-Akt-FLIP pathway.
Author: Nam, Seon Young|Amoscato, Andrew A|Lee, Yong J
PMID: 11821946
Journal: Biochem Biophys Res Commun. 2002 Mar 29;292(2):347-54.
Title: Caspase-8 gene transduction augments radiation-induced apoptosis in DLD-1 cells.
Author: Uchida, Hiroaki|Shinoura, Nobusada|Kitayama, Joji|Watanabe, Toshiaki|Nagawa, Hirokazu|Hamada, Hirofumi
PMID: 11906168
Journal: Cancer Res. 2002 Mar 15;62(6):1583-7.
Title: Requirement of BAX for TRAIL/Apo2L-induced apoptosis of colorectal cancers: synergism with sulindac-mediated inhibition of Bcl-x(L).
Author: Ravi, Rajani|Bedi, Atul
PMID: 11912124
Journal: J Cancer Res Clin Oncol. 2002 Apr;128(4):223-30.
Title: Induction of apoptosis by norcantharidin in human colorectal carcinoma cell lines: involvement of the CD95 receptor/ligand.
Author: Peng, F|Wei, Y-Q|Tian, L|Yang, L|Zhao, X|Lu, Y|Mao, Y-Q|Kan, B|Lei, S|Wang, G-S|Jiang, Y|Wang, Q-R|Luo, F|Zou, L-Q|Liu, J-Y
PMID: 11935314
Journal: J Biol Chem. 2002 Jul 5;277(27):24631-7. Epub 2002 Apr 29.
Title: Distinct intracellular signaling in tumor necrosis factor-related apoptosis-inducing ligand- and CD95 ligand-mediated apoptosis.
Author: Velthuis, Jurjen H L|Rouschop, Kasper M A|De Bont, Hans J G M|Mulder, Gerard J|Nagelkerke, J Fred
PMID: 11980895
Journal: Oncogene. 2002 Sep 5;21(39):6032-40.
Title: Apo2L/TRAIL differentially modulates the apoptotic effects of sulindac and a COX-2 selective non-steroidal anti-inflammatory agent in Bax-deficient cells.
Author: He, Qin|Luo, Xiuquan|Huang, Ying|Sheikh, M Saeed
PMID: 12203115
Journal: Cancer Res. 2002 Sep 1;62(17):4903-8.
Title: Cyclooxygenase-2 overexpression inhibits death receptor 5 expression and confers resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human colon cancer cells.
Author: Tang, Ximing|Sun, Yun Jie|Half, Elizabeth|Kuo, M Tien|Sinicrope, Frank
PMID: 12208739
Journal: Cancer Res. 2002 Nov 1;62(21):6323-8.
Title: Cyclooxygenase-2 overexpression reduces apoptotic susceptibility by inhibiting the cytochrome c-dependent apoptotic pathway in human colon cancer cells.
Author: Sun, Yunjie|Tang, Xi Ming|Half, Elizabeth|Kuo, M Tien|Sinicrope, Frank A
PMID: 12414664
Journal: Carcinogenesis. 2002 Dec;23(12):2087-93.
Title: Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells.
Author: Liu, Jian-Jun|Nilsson, Ake|Oredsson, Stina|Badmaev, Vladimir|Zhao, Wan-Zhou|Duan, Rui-Dong
PMID: 12507932
Journal: Biochem J. 2003 Apr 1;371(Pt 1):115-24.
Title: The anti-apoptotic effect of leukotriene D4 involves the prevention of caspase 8 activation and Bid cleavage.
Author: Wikstrom, Katarina|Juhas, Maria|Sjolander, Anita
PMID: 12482325
Journal: Cancer Res. 2003 Feb 1;63(3):621-6.
Title: Rapid induction of apoptosis by combination of flavopiridol and tumor necrosis factor (TNF)-alpha or TNF-related apoptosis-inducing ligand in human cancer cell lines.
Author: Kim, Dong-Myung|Koo, Sun-Young|Jeon, Kiwan|Kim, Min Hyung|Lee, Jinho|Hong, Chang Yong|Jeong, ShinWu
PMID: 12566305
Journal: Mol Cancer Ther. 2003 Feb;2(2):139-50.
Title: Flavopiridol induces apoptosis in glioma cell lines independent of retinoblastoma and p53 tumor suppressor pathway alterations by a caspase-independent pathway.
Author: Alonso, Michelle|Tamasdan, Cristina|Miller, Douglas C|Newcomb, Elizabeth W
PMID: 12589031
Journal: Br J Cancer. 2003 Mar 10;88(5):788-95.
Title: Endothelin-receptor antagonists are proapoptotic and antiproliferative in human colon cancer cells.
Author: Peduto Eberl, L|Bovey, R|Juillerat-Jeanneret, L
PMID: 12618891
Journal: Cancer Res. 2003 Mar 15;63(6):1254-61.
Title: Caspase-8 and apoptosis-inducing factor mediate a cytochrome c-independent pathway of apoptosis in human colon cancer cells induced by the dietary phytochemical chlorophyllin.
Author: Diaz, G Dario|Li, Qingjie|Dashwood, Roderick H
PMID: 12649185
Journal: Oncogene. 2003 Mar 27;22(12):1807-16.
Title: Chemotherapy enhances TNF-related apoptosis-inducing ligand DISC assembly in HT29 human colon cancer cells.
Author: Lacour, Sandrine|Micheau, Olivier|Hammann, Arlette|Drouineaud, Veronique|Tschopp, Jurg|Solary, Eric|Dimanche-Boitrel, Marie-Therese
PMID: 12660816
Journal: Cancer Res. 2003 Apr 1;63(7):1483-9.
Title: Bax plays a pivotal role in thapsigargin-induced apoptosis of human colon cancer HCT116 cells by controlling Smac/Diablo and Omi/HtrA2 release from mitochondria.
Author: Yamaguchi, Hirohito|Bhalla, Kapil|Wang, Hong-Gang
PMID: 12670894
Journal: J Gene Med. 2003 Apr;5(4):287-99.
Title: 5-Fluorouracil efficiently enhanced apoptosis induced by adenovirus-mediated transfer of caspase-8 in DLD-1 colon cancer cells.
Author: Uchida, Hiroaki|Shinoura, Nobusada|Kitayama, Joji|Watanabe, Toshiaki|Nagawa, Hirokazu|Hamada, Hirofumi
PMID: 12692863
Journal: Mol Pharmacol. 2003 Jun;63(6):1281-8.
Title: Decrease in survival threshold of quiescent colon carcinoma cells in the presence of a small molecule integrin antagonist.
Author: Burbridge, Mike F|Venot, Virginie|Casara, Patrick J|Perron-Sierra, Francoise|Hickman, John A|Tucker, Gordon C
PMID: 12761337
Journal: Eur J Cancer. 2003 Jun;39(9):1310-7.
Title: Thymidylate synthase inhibition triggers apoptosis via caspases-8 and -9 in both wild-type and mutant p53 colon cancer cell lines.
Author: Backus, H H J|Wouters, D|Ferreira, C G|van Houten, V M M|Brakenhoff, R H|Pinedo, H M|Peters, G J
PMID: 12763222
Journal: Br J Cancer. 2003 Jul 21;89(2):363-73.
Title: Differential modulation of the TRAIL receptors and the CD95 receptor in colon carcinoma cell lines.
Author: van Geelen, C M M|de Vries, E G E|Le, T K P|van Weeghel, R P|de Jong, S
PMID: 12865931
Journal: Oncogene. 2003 Aug 7;22(32):4953-63.
Title: The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells.
Author: Johnson, Thomas R|Stone, Kimberley|Nikrad, Malti|Yeh, Tammie|Zong, Wei-Xing|Thompson, Craig B|Nesterov, Alexandre|Kraft, Andrew S
PMID: 12902978
Journal: Gastroenterology. 2003 Sep;125(3):708-15.
Title: Inactivating mutations of caspase-8 gene in colorectal carcinomas.
Author: Kim, Hong Sug|Lee, Jong Woo|Soung, Young Hwa|Park, Won Sang|Kim, Su Young|Lee, Jong Heun|Park, Jik Young|Cho, Youg Gu|Kim, Chang Jae|Jeong, Seong Whan|Nam, Suk Woo|Kim, Sang Ho|Lee, Jung Young|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 12949717
Journal: Korean J Gastroenterol. 2003 Jul;42(1):35-41.
Title: [Effects of peroxisome proliferator-activated receptor-gamma agonist on Fas-mediated apoptosis in HT-29 cells].
Author: Chung, Yong Woo|Han, Dong Soo|Kang, Eun Kyung|Lee, Jin Sook|Lee, Hang Rak|Kim, Jin Bae|Park, Jun Yong|Kim, Yong Seok|Lee, Oh Young|Choi, Ho Soon|Sohn, Joo Hyun|Yoo, Dae Hyun|Hahm, Joon Soo
PMID: 14532729
Journal: Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):15095-100. Epub 2003 Nov 26.
Title: Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy.
Author: Wang, Shulin|El-Deiry, Wafik S
PMID: 14645705
Journal: Cancer Res. 2004 Feb 1;64(3):1110-3.
Title: Induction of apoptosis and down-regulation of Bcl-XL in cancer cells by a novel small molecule, 2[[3-(2,3-dichlorophenoxy)propyl]amino]ethanol.
Author: Wu, Shuhong|Zhu, Hongbo|Gu, Jian|Zhang, Lidong|Teraishi, Fuminori|Davis, John J|Jacob, Dietmar A|Fang, Bingliang
PMID: 14871845
Journal: J Biol Chem. 2004 Jun 11;279(24):25813-22. Epub 2004 Apr 8.
Title: Sulforaphane-induced G2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25C.
Author: Singh, Shivendra V|Herman-Antosiewicz, Anna|Singh, Ajita V|Lew, Karen L|Srivastava, Sanjay K|Kamath, Ravindra|Brown, Kevin D|Zhang, Lin|Baskaran, Rajasekaran
PMID: 15073169
Journal: Dis Colon Rectum. 2004 Jun;47(6):919-28.
Title: Effects of estrogen on messenger ribonucleic acid expression patterns of extracellular matrix proteases in the primate colon.
Author: Mills, Steven|Young, Kelly A|Whiteford, Mark H
PMID: 15108029
Journal: Cell Res. 2004 Apr;14(2):117-24.
Title: LIGHT sensitizes IFN-gamma-mediated apoptosis of HT-29 human carcinoma cells through both death receptor and mitochondria pathways.
Author: Zhang, Man Chao|Liu, Hong Peng|Demchik, Lisa L|Zhai, Yi Fan|Yang, Da Jun
PMID: 15115612
Journal: Mol Ther. 2004 May;9(5):666-73.
Title: Overcoming acquired resistance to TRAIL by chemotherapeutic agents and calpain inhibitor I through distinct mechanisms.
Author: Zhu, Hongbo|Zhang, Lidong|Huang, Xuefeng|Davis, John J|Jacob, Dietmar A|Teraishi, Fuminori|Chiao, Paul|Fang, Bingliang
PMID: 15120327
Journal: J Interferon Cytokine Res. 2004 Apr;24(4):231-43.
Title: IFN-beta induces caspase-mediated apoptosis by disrupting mitochondria in human advanced stage colon cancer cell lines.
Author: Juang, Shin-Hun|Wei, Sung-Jen|Hung, Yi-Mei|Hsu, Chiung-Yueh|Yang, Den-Mei|Liu, Ko-Jiunn|Chen, Wei-Shone|Yang, Wen K
PMID: 15144569
Journal: J Biol Chem. 2004 Aug 20;279(34):35829-39. Epub 2004 May 20.
Title: Deficient tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor transport to the cell surface in human colon cancer cells selected for resistance to TRAIL-induced apoptosis.
Author: Jin, Zhaoyu|McDonald, E Robert 3rd|Dicker, David T|El-Deiry, Wafik S
PMID: 15155747
Journal: Clin Cancer Res. 2004 May 15;10(10):3562-71.
Title: The roles of thymidylate synthase and p53 in regulating Fas-mediated apoptosis in response to antimetabolites.
Author: Longley, Daniel Broderick|Allen, Wendy Louise|McDermott, Ultan|Wilson, Timothy Richard|Latif, Tariq|Boyer, John|Lynch, Maria|Johnston, Patrick Gerard
PMID: 15161716
Journal: Carcinogenesis. 2004 Oct;25(10):1961-6. Epub 2004 Jun 10.
Title: Lactoferrin enhances Fas expression and apoptosis in the colon mucosa of azoxymethane-treated rats.
Author: Fujita, Ken-ichi|Matsuda, Eiji|Sekine, Kazunori|Iigo, Masaaki|Tsuda, Hiroyuki
PMID: 15192017
Journal: Carcinogenesis. 2004 Oct;25(10):1867-77. Epub 2004 Jun 17.
Title: Ectopic expression of Bcl-XL or Ku70 protects human colon cancer cells (SW480) against curcumin-induced apoptosis while their down-regulation potentiates it.
Author: Rashmi, Ramachandran|Kumar, Santhosh|Karunagaran, Devarajan
PMID: 15205359
Journal: Cancer Lett. 2004 Aug 10;211(2):175-88.
Title: Involvement of proapoptotic Bcl-2 family members in parthenolide-induced mitochondrial dysfunction and apoptosis.
Author: Zhang, Siyuan|Ong, Choon-Nam|Shen, Han-Ming
PMID: 15219941
Journal: Int J Cancer. 2004 Nov 10;112(3):433-45.
Title: Unconjugated bilirubin induces apoptosis in colon cancer cells by triggering mitochondrial depolarization.
Author: Keshavan, Pavitra|Schwemberger, Sandy J|Smith, Darcey L H|Babcock, George F|Zucker, Stephen D
PMID: 15382069
Journal: FEBS Lett. 2004 Nov 5;577(1-2):309-13.
Title: Ethanol acts as a potent agent sensitizing colon cancer cells to the TRAIL-induced apoptosis.
Author: Vaculova, Alena|Hofmanova, Jirina|Soucek, Karel|Andera, Ladislav|Kozubik, Alois
PMID: 15527805
Journal: Clin Cancer Res. 2004 Dec 15;10(24):8284-92.
Title: Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis is inhibited by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human colon cancer cells.
Author: Sinicrope, Frank A|Penington, Robert C|Tang, Xi Ming
PMID: 15623604
Journal: J Biol Chem. 2005 Mar 4;280(9):7634-44. Epub 2004 Dec 17.
Title: Tumor necrosis factor alpha-dependent drug resistance to purine and pyrimidine analogues in human colon tumor cells mediated through IKK.
Author: Wang, Ling-Chi|Okitsu, Cindy Yen|Zandi, Ebrahim
PMID: 15611081
Journal: Carcinogenesis. 2005 Apr;26(4):713-23. Epub 2005 Jan 20.
Title: Human colon cancer cells lacking Bax resist curcumin-induced apoptosis and Bax requirement is dispensable with ectopic expression of Smac or downregulation of Bcl-XL.
Author: Rashmi, Ramachandran|Kumar, Santhosh|Karunagaran, Devarajan
PMID: 15661804
Journal: Mol Cancer Res. 2005 Jan;3(1):21-31.
Title: Apolipoprotein l6, a novel proapoptotic Bcl-2 homology 3-only protein, induces mitochondria-mediated apoptosis in cancer cells.
Author: Liu, Zhihe|Lu, Huimei|Jiang, Zeyu|Pastuszyn, Andrzej|Hu, Chien-an A
PMID: 15671246
Journal: Oncogene. 2005 Mar 17;24(12):2050-8.
Title: Casein kinase II (CK2) enhances death-inducing signaling complex (DISC) activity in TRAIL-induced apoptosis in human colon carcinoma cell lines.
Author: Izeradjene, Kamel|Douglas, Leslie|Delaney, Addison|Houghton, Janet A
PMID: 15688023
Journal: In Vivo. 2005 Jan-Feb;19(1):93-102.
Title: Induction of apoptosis in human colon cancer HCT116 cells treated with an extract of the plant product, Chios mastic gum.
Author: Balan, Kannan V|Demetzos, Costas|Prince, Jeffrey|Dimas, Konstantine|Cladaras, Margarita|Han, Zhiyong|Wyche, James H|Pantazis, Panayotis
PMID: 15796160
Journal: World J Gastroenterol. 2005 Apr 28;11(16):2482-5.
Title: Expression of cellular FLICE-inhibitory protein and its association with p53 mutation in colon cancer.
Author: Zhou, Xiao-Dong|Yu, Jie-Ping|Chen, Hong-Xia|Yu, Hong-Gang|Luo, He-Sheng
PMID: 15832422
Journal: Br J Cancer. 2005 Apr 25;92(8):1430-41.
Title: HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo.
Author: Pukac, L|Kanakaraj, P|Humphreys, R|Alderson, R|Bloom, M|Sung, C|Riccobene, T|Johnson, R|Fiscella, M|Mahoney, A|Carrell, J|Boyd, E|Yao, X T|Zhang, L|Zhong, L|von Kerczek, A|Shepard, L|Vaughan, T|Edwards, B|Dobson, C|Salcedo, T|Albert, V
PMID: 15846298
Journal: Carcinogenesis. 2005 Oct;26(10):1716-30. Epub 2005 May 19.
Title: Justicidin A decreases the level of cytosolic Ku70 leading to apoptosis in human colorectal cancer cells.
Author: Lee, Jenq-Chang|Lee, Chao-Hung|Su, Chun-Li|Huang, Chung-Wei|Liu, Hsiao-Sheng|Lin, Chun-Nan|Won, Shen-Jeu
PMID: 15905197
Journal: World J Gastroenterol. 2005 May 28;11(20):3040-5.
Title: Molecular mechanisms of denbinobin-induced anti-tumorigenesis effect in colon cancer cells.
Author: Yang, Kuo-Ching|Uen, Yih-Huei|Suk, Fat-Moon|Liang, Yu-Chih|Wang, Ying-Jan|Ho, Yuan-Soon|Li, I-Hsuan|Lin, Shyr-Yi
PMID: 15918186
Journal: Food Chem Toxicol. 2005 Oct;43(10):1483-95.
Title: Molecular mechanisms of econazole-induced toxicity on human colon cancer cells: G0/G1 cell cycle arrest and caspase 8-independent apoptotic signaling pathways.
Author: Ho, Yuan-Soon|Wu, Chih-Hsiung|Chou, Hsiao-Min|Wang, Ying-Jan|Tseng, How|Chen, Chien-Ho|Chen, Li-Ching|Lee, Chia-Hwa|Lin, Shyr-Yi
PMID: 15919146
Journal: Mol Nutr Food Res. 2005 Sep;49(9):837-43.
Title: Xanthohumol induces apoptosis in cultured 40-16 human colon cancer cells by activation of the death receptor- and mitochondrial pathway.
Author: Pan, Lydia|Becker, Hans|Gerhauser, Clarissa
PMID: 15995977
Journal: Neoplasia. 2005 Jun;7(6):594-602.
Title: Accelerated degradation of caspase-8 protein correlates with TRAIL resistance in a DLD1 human colon cancer cell line.
Author: Zhang, Lidong|Zhu, Hongbo|Teraishi, Fuminori|Davis, John J|Guo, Wei|Fan, Zhen|Fang, Bingliang
PMID: 16036110
Journal: Cancer Biol Ther. 2005 Jul;4(7):781-6. Epub 2005 Jul 6.
Title: Proteasome inhibitors-mediated TRAIL resensitization and Bik accumulation.
Author: Zhu, Hongbo|Guo, Wei|Zhang, Lidong|Wu, Shuhong|Teraishi, Fuminori|Davis, John J|Dong, Fengqin|Fang, Bingliang
PMID: 16082182
Journal: Clin Colorectal Cancer. 2005 Jul;5(2):114-8.
Title: Tumor response to neoadjuvant chemoradiation therapy for rectal adenocarcinoma is mediated by p53-dependent and caspase 8-dependent apoptotic pathways.
Author: Kelley, Scott T|Coppola, Domenico|Yeatman, Timothy|Marcet, Jorge
PMID: 16098252
Journal: Cancer Res. 2005 Aug 15;65(16):7436-45.
Title: Reactive oxygen species regulate caspase activation in tumor necrosis factor-related apoptosis-inducing ligand-resistant human colon carcinoma cell lines.
Author: Izeradjene, Kamel|Douglas, Leslie|Tillman, David M|Delaney, Addison B|Houghton, Janet A
PMID: 16103097
Journal: Surgery. 2005 Aug;138(2):391-7.
Title: Targeted RNA interference of PI3K pathway components sensitizes colon cancer cells to TNF-related apoptosis-inducing ligand (TRAIL).
Author: Rychahou, Piotr G|Murillo, Carlos A|Evers, B Mark
PMID: 16153452
Journal: Anticancer Res. 2005 May-Jun;25(3B):2269-76.
Title: Enterolactone induces apoptosis and inhibits growth of Colo 201 human colon cancer cells both in vitro and in vivo.
Author: Danbara, Naoyuki|Yuri, Takashi|Tsujita-Kyutoku, Miki|Tsukamoto, Reiko|Uehara, Norihisa|Tsubura, Airo
PMID: 16158974
Journal: Cancer Res. 2005 Oct 1;65(19):8706-14.
Title: A novel isoform of TUCAN is overexpressed in human cancer tissues and suppresses both caspase-8- and caspase-9-mediated apoptosis.
Author: Yamamoto, Masaaki|Torigoe, Toshihiko|Kamiguchi, Kenjiro|Hirohashi, Yoshihiko|Nakanishi, Katsuya|Nabeta, Chika|Asanuma, Hiroko|Tsuruma, Tetsuhiro|Sato, Takashi|Hata, Fumitake|Ohmura, Tousei|Yamaguchi, Koji|Kurotaki, Takehiro|Hirata, Koichi|Sato, Noriyuki
PMID: 16204039
Journal: Mol Cancer Ther. 2005 Oct;4(10):1475-83.
Title: Sulindac sulfide-induced apoptosis is enhanced by a small-molecule Bcl-2 inhibitor and by TRAIL in human colon cancer cells overexpressing Bcl-2.
Author: Sinicrope, Frank A|Penington, Robert C
PMID: 16227396
Journal: Mol Cancer Ther. 2005 Dec;4(12):2026-36.
Title: Chemotherapy and TRAIL-mediated colon cancer cell death: the roles of p53, TRAIL receptors, and c-FLIP.
Author: Galligan, Leeona|Longley, Daniel B|McEwan, Miranda|Wilson, Timothy R|McLaughlin, Kirsty|Johnston, Patrick G
PMID: 16373718
Journal: Oncol Res. 2005;15(7-8):385-92.
Title: Irinotecan/5-fluorouracil combination induces alterations in mitochondrial membrane potential and caspases on colon cancer cell lines.
Author: Grivicich, Ivana|Regner, Andrea|da Rocha, Adriana B|Grass, Luciano B|Alves, Pedro A G|Kayser, Guilherme B|Schwartsmann, Gilberto|Henriques, Joao A
PMID: 16491956
Journal: Biomed Pharmacother. 2005 Oct;59 Suppl 2:S370-4.
Title: Gene targeting approach to selectively kill colon cancer cells, with hyperactive K-Ras pathway.
Author: Dvory-Sobol, H|Kazanov, D|Arber, N
PMID: 16507412
Journal: Placenta. 2006 Apr-May;27(4-5):375-83. Epub 2005 Jun 21.
Title: Inhibition of DLX4 promotes apoptosis in choriocarcinoma cell lines.
Author: Sun, Y|Lu, X|Yin, L|Zhao, F|Feng, Y
PMID: 15975650
Journal: Int J Cancer. 2006 Jan 15;118(2):326-34.
Title: PKCdelta-mediated regulation of FLIP expression in human colon cancer cells.
Author: Wang, Qingding|Wang, Xiaofu|Zhou, Yuning|Evers, B Mark
PMID: 16052516
Journal: Cell Death Differ. 2006 Feb;13(2):189-201.
Title: Agonists of an ecdysone-inducible mammalian expression system inhibit Fas Ligand- and TRAIL-induced apoptosis in the human colon carcinoma cell line RKO.
Author: Oehme, I|Bosser, S|Zornig, M
PMID: 16082389
Journal: Int J Cancer. 2006 Apr 1;118(7):1790-7.
Title: Exploring SNP-SNP interactions and colon cancer risk using polymorphism interaction analysis.
Author: Goodman, Julie E|Mechanic, Leah E|Luke, Brian T|Ambs, Stefan|Chanock, Stephen|Harris, Curtis C
PMID: 16217767
Journal: Oncogene. 2006 Feb 9;25(6):838-48.
Title: c-FLIP inhibits chemotherapy-induced colorectal cancer cell death.
Author: Longley, D B|Wilson, T R|McEwan, M|Allen, W L|McDermott, U|Galligan, L|Johnston, P G
PMID: 16247474
Journal: Cancer Lett. 2006 Sep 28;241(2):268-74.
Title: Induction of apoptosis and cell cycle arrest by a specific c-Jun NH2-terminal kinase (JNK) inhibitor, SP-600125, in gastrointestinal cancers.
Author: Xia, Harry Hua-Xiang|He, Hua|De Wang, Ji|Gu, Qing|Lin, Marie C M|Zou, Bing|Yu, Li Fen|Sun, Yun Wei|Chan, Annie O O|Kung, Hsiang Fu|Wong, Benjamin Chun-Yu
PMID: 16337741
Journal: J Nutr Biochem. 2006 Sep;17(9):611-25.
Title: The dietary hydrolysable tannin punicalagin releases ellagic acid that induces apoptosis in human colon adenocarcinoma Caco-2 cells by using the mitochondrial pathway.
Author: Larrosa, Mar|Tomas-Barberan, Francisco A|Espin, Juan Carlos
PMID: 16426830
Journal: J Biol Chem. 2006 Jun 30;281(26):17599-611. Epub 2006 Apr 14.
Title: Caspase-2 triggers Bax-Bak-dependent and -independent cell death in colon cancer cells treated with resveratrol.
Author: Mohan, John|Gandhi, Alankaram Arul|Bhavya, Balan Chandrika|Rashmi, Ramachandran|Karunagaran, Devarajan|Indu, Ramachandran|Santhoshkumar, Thankayyan Ratnabhai
PMID: 16617056
Journal: EMBO J. 2006 May 3;25(9):1895-905.
Title: Src kinase phosphorylates Caspase-8 on Tyr380: a novel mechanism of apoptosis suppression.
Author: Cursi, Silvia|Rufini, Alessandra|Stagni, Venturina|Condo, Ivano|Matafora, Vittoria|Bachi, Angela|Bonifazi, Antonio Paniccia|Coppola, Luigi|Superti-Furga, Giulio|Testi, Roberto|Barila, Daniela
PMID: 16619028
Journal: Oncogene. 2006 Sep 14;25(41):5640-7. Epub 2006 Apr 17.
Title: Proline oxidase activates both intrinsic and extrinsic pathways for apoptosis: the role of ROS/superoxides, NFAT and MEK/ERK signaling.
Author: Liu, Y|Borchert, G L|Surazynski, A|Hu, C-A|Phang, J M
PMID: 16619034
Journal: Mol Cell Biochem. 2006 Sep;289(1-2):101-9.
Title: Over-expressed estrogen receptor-alpha up-regulates hTNF-alpha gene expression and down-regulates beta-catenin signaling activity to induce the apoptosis and inhibit proliferation of LoVo colon cancer cells.
Author: Hsu, Hsi-Hsien|Cheng, Sue-Fei|Chen, Li-Mien|Liu, Jer-Yu|Chu, Chun-Hsien|Weng, Yi-Jiun|Li, Zih-Ying|Lin, Chung-Sheng|Lee, Shin-Da|Kuo, Wei-Wen|Huang, Chih-Yang
PMID: 16628468
Journal: J Gastroenterol Hepatol. 2006 Jan;21(1 Pt 1):84-91.
Title: Fas-associated phosphatase-1 promotes Fas-mediated apoptosis in human colon cancer cells: novel function of FAP-1.
Author: Miyazaki, Takako|Atarashi, Yoshinari|Yasumura, Satoshi|Minatoya, Isao|Ogawa, Kohei|Iwamoto, Masaya|Minemura, Masami|Shimizu, Yukihiro|Sato, Taka-Aki|Watanabe, Akiharu|Sugiyama, Toshiro
PMID: 16706817
Journal: Chin J Physiol. 2006 Apr 30;49(2):110-6.
Title: Apoptotic effects of over-expressed estrogen receptor-beta on LoVo colon cancer cell is mediated by p53 signalings in a ligand-dependent manner.
Author: Hsu, Hsi-Hsien|Cheng, Sue-Fei|Wu, Cheng-Chung|Chu, Chun-Hsien|Weng, Yi-Jiun|Lin, Chung-Sheng|Lee, Shin-Da|Wu, Hung-Chien|Huang, Chih-Yang|Kuo, Wei-Wen
PMID: 16830793
Journal: Clin Cancer Res. 2006 Jul 15;12(14 Pt 1):4350-6.
Title: TRAIL induces apoptosis in human colorectal adenoma cell lines and human colorectal adenomas.
Author: Jalving, Mathilde|de Jong, Steven|Koornstra, Jan J|Boersma-van Ek, Wytske|Zwart, Nynke|Wesseling, Jelle|de Vries, Elisabeth G E|Kleibeuker, Jan H
PMID: 16857810
Journal: Apoptosis. 2006 Oct;11(10):1801-11.
Title: PPARgamma is a key target of butyrate-induced caspase-3 activation in the colorectal cancer cell line Caco-2.
Author: Schwab, Markus|Reynders, Veerle|Ulrich, Sandra|Zahn, Nadine|Stein, Jurgen|Schroder, Oliver
PMID: 16927016
Journal: APMIS. 2006 Sep;114(9):646-50.
Title: Mutational analysis of the CASP6 gene in colorectal and gastric carcinomas.
Author: Lee, Jong Woo|Kim, Mee Ran|Soung, Young Hwa|Nam, Suk Woo|Kim, Sang Ho|Lee, Jung Young|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 16948818
Journal: Pathol Oncol Res. 2006;12(3):133-42. Epub 2006 Sep 23.
Title: Proteasome inhibitors sensitize colon carcinoma cells to TRAIL-induced apoptosis via enhanced release of Smac/DIABLO from the mitochondria.
Author: Nagy, Katalin|Szekely-Szuts, Kinga|Izeradjene, Kamel|Douglas, Leslie|Tillman, Mike|Barti-Juhasz, Helga|Dominici, Massimo|Spano, Carlotta|Luca Cervo, Gian|Conte, Pierfranco|Houghton, Janet A|Mihalik, Rudolf|Kopper, Laszlo|Petak, Istvan
PMID: 16998592
Journal: Cancer Biol Ther. 2006 Nov;5(11):1511-20. Epub 2006 Nov 19.
Title: Photochemically mediated delivery of AdhCMV-TRAIL augments the TRAIL-induced apoptosis in colorectal cancer cell lines.
Author: Engesaeter, Birgit O|Bonsted, Anette|Lillehammer, Trine|Engebraaten, Olav|Berg, Kristian|Maelandsmo, Gunhild M
PMID: 17012835
Journal: J Nutr. 2007 Jan;137(1):31-6.
Title: Activation of caspase-8 contributes to 3,3'-Diindolylmethane-induced apoptosis in colon cancer cells.
Author: Kim, Eun Ji|Park, So Young|Shin, Hyun-Kyung|Kwon, Dae Young|Surh, Young-Joon|Park, Jung Han Yoon
PMID: 17182797
Journal: Mol Cell Biochem. 2007 Jun;300(1-2):227-37.
Title: A highly polar xanthophyll of 9'-cis-neoxanthin induces apoptosis in HCT116 human colon cancer cells through mitochondrial dysfunction.
Author: Terasaki, Masaru|Asai, Akira|Zhang, Hong|Nagao, Akihiko
PMID: 17186379
Journal: Mol Carcinog. 2007 Mar;46(3):231-41.
Title: Pinocembrin triggers Bax-dependent mitochondrial apoptosis in colon cancer cells.
Author: Kumar, M A Suresh|Nair, Mangalam|Hema, P S|Mohan, John|Santhoshkumar, T R
PMID: 17186548
Journal: Apoptosis. 2007 Feb;12(2):423-31.
Title: Alpha-tocopheryl succinate sensitizes human colon cancer cells to exisulind-induced apoptosis.
Author: Lim, Soo-Jeong|Lee, Young-Ju|Park, Dae-Hun|Lee, Eunmyong|Choi, Moon-Kyung|Park, Wanseo|Chun, Kyung-Hee|Choi, Han-Gon|Cho, Jung Sik
PMID: 17191116
Journal: Int J Oncol. 2007 Mar;30(3):537-48.
Title: Apoptosis signalling mechanisms in human cancer cells induced by Calphostin-PDT.
Author: Olivo, Malini|Ali-Seyed, Mohamed
PMID: 17273754
Journal: Biosci Biotechnol Biochem. 2007 Apr;71(4):1069-72.
Title: Induction of apoptosis in DLD-1 human colon cancer cells by peridinin isolated from the dinoflagellate, Heterocapsa triquetra.
Author: Sugawara, Tatsuya|Yamashita, Kyoko|Sakai, Shota|Asai, Akira|Nagao, Akihiko|Shiraishi, Tomotaka|Imai, Ichiro|Hirata, Takashi
PMID: 17420600
Journal: Apoptosis. 2007 Jul;12(7):1299-315.
Title: Bid is cleaved upstream of caspase-8 activation during TRAIL-mediated apoptosis in human osteosarcoma cells.
Author: Garnett, Theodore O|Filippova, Maria|Duerksen-Hughes, Penelope Jayne
PMID: 17431792
Journal: Cancer Res. 2007 May 15;67(10):4774-82.
Title: Carcinoembryonic antigen inhibits anoikis in colorectal carcinoma cells by interfering with TRAIL-R2 (DR5) signaling.
Author: Samara, Raed N|Laguinge, Luciana M|Jessup, J Milburn
PMID: 17510406
Journal: World J Gastroenterol. 2007 May 28;13(20):2811-8.
Title: Mechanisms involved in Korean mistletoe lectin-induced apoptosis of cancer cells.
Author: Khil, Lee-Yong|Kim, Wi|Lyu, Suyun|Park, Won-Bong|Yoon, Ji-Won|Jun, Hee-Sook
PMID: 17569116
Journal: Cancer Res. 2007 Jun 15;67(12):5754-62.
Title: c-FLIP: a key regulator of colorectal cancer cell death.
Author: Wilson, Timothy R|McLaughlin, Kirsty M|McEwan, Miranda|Sakai, Hidekazu|Rogers, Katherine M A|Redmond, Kelly M|Johnston, Patrick G|Longley, Daniel B
PMID: 17575142
Journal: Mol Pharmacol. 2007 Sep;72(3):704-14. Epub 2007 Jun 19.
Title: Low-dose BBR3610 toxicity in colon cancer cells is p53-independent and enhanced by inhibition of epidermal growth factor receptor (ERBB1)-phosphatidyl inositol 3 kinase signaling.
Author: Mitchell, Clint|Kabolizadeh, Peyman|Ryan, John|Roberts, John D|Yacoub, Adly|Curiel, David T|Fisher, Paul B|Hagan, Michael P|Farrell, Nicholas P|Grant, Steven|Dent, Paul
PMID: 17578896
Journal: Arch Toxicol. 2007 Oct;81(10):719-28. Epub 2007 Aug 3.
Title: Berberine induces apoptosis in SW620 human colonic carcinoma cells through generation of reactive oxygen species and activation of JNK/p38 MAPK and FasL.
Author: Hsu, Wen-Hsiu|Hsieh, Yih-Shou|Kuo, Hsing-Chun|Teng, Chun-Yuh|Huang, Hai-I|Wang, Chau-Jong|Yang, Shun-Fa|Liou, Yi-Sheng|Kuo, Wu-Hsien
PMID: 17673978
Journal: Cell Oncol. 2007;29(5):409-19.
Title: Independent induction of caspase-8 and cFLIP expression during colorectal carcinogenesis in sporadic and HNPCC adenomas and carcinomas.
Author: Heijink, D M|Kleibeuker, J H|Jalving, M|Boersma-van Ek, W|Koornstra, J J|Wesseling, J|de Jong, S
PMID: 17726263
Journal: Clin Cancer Res. 2007 Sep 1;13(17):5070-5.
Title: Overexpression of FLIPL is an independent marker of poor prognosis in colorectal cancer patients.
Author: Ullenhag, Gustave J|Mukherjee, Abhik|Watson, Nicholas F S|Al-Attar, Ahmad H|Scholefield, John H|Durrant, Lindy G
PMID: 17785559
Journal: J Med Food. 2007 Sep;10(3):467-72.
Title: Effect of methanolic extract from silkworm droppings on proliferation and caspase activity in HT-29 human colon cancer cells.
Author: Hwang, Ji-Hwan|Kim, Ju-Young|Cha, Mi-Ran|Park, Hae-Ryong
PMID: 17887940
Journal: J Biol Chem. 2007 Nov 23;282(47):34457-67. Epub 2007 Sep 26.
Title: A novel interaction between procaspase 8 and SPARC enhances apoptosis and potentiates chemotherapy sensitivity in colorectal cancers.
Author: Tang, Michelle J|Tai, Isabella T
PMID: 17897953
Journal: Cancer Biother Radiopharm. 2007 Oct;22(5):672-83.
Title: Human allogeneic and murine xenogeneic dendritic cells are cytotoxic to human tumor cells via two distinct pathways.
Author: Schiltz, Patric M|Lee, Gregory J|Zhang, Jian Gang|Hoa, Neil|Wepsic, H Terry|Dillman, Robert O|Jadus, Martin R
PMID: 17979570
Journal: J Med Food. 2007 Dec;10(4):581-6.
Title: Induction of apoptosis in HT-29 colon cancer cells by phloretin.
Author: Park, So Young|Kim, Eun Ji|Shin, Hyun-Kyung|Kwon, Dae Young|Kim, Myung Sunny|Surh, Young-Joon|Park, Jung Han Yoon
PMID: 18158826
Journal: Cancer Res. 2008 Feb 1;68(3):880-8.
Title: Systematic high-content proteomic analysis reveals substantial immunologic changes in colorectal cancer.
Author: Berndt, Uta|Philipsen, Lars|Bartsch, Sebastian|Wiedenmann, Bertram|Baumgart, Daniel C|Hammerle, Marcus|Sturm, Andreas
PMID: 18245490
Journal: Cancer Res. 2008 Feb 1;68(3):909-17.
Title: DR5 receptor mediates anoikis in human colorectal carcinoma cell lines.
Author: Laguinge, Luciana M|Samara, Raed N|Wang, Wenge|El-Deiry, Wafik S|Corner, Georgia|Augenlicht, Leonard|Mishra, Lopa|Jessup, J Milburn
PMID: 18245494
Journal: Br J Cancer. 2008 Apr 22;98(8):1434-6.
Title: CASP8 variants D302H and -652 6N ins/del do not influence the risk of colorectal cancer in the United Kingdom population.
Author: Pittman, A M|Broderick, P|Sullivan, K|Fielding, S|Webb, E|Penegar, S|Tomlinson, I|Houlston, R S
PMID: 18362937
Journal: Biochem Pharmacol. 2008 May 1;75(9):1729-42.
Title: Critical role of Bid and Bax in indirubin-3'-monoxime-induced apoptosis in human cancer cells.
Author: Shi, Jie|Shen, Han-Ming
PMID: 18377873
Journal: Cancer Lett. 2008 Aug 8;266(2):209-15.
Title: Signaling and regulatory mechanisms of integrin alphavbeta6 on the apoptosis of colon cancer cells.
Author: Zhao-Yang, Zhang|Ke-Sen, Xu|Qing-Si, He|Wei-Bo, Niu|Jia-Yong, Wang|Yue-Tang, Mi|Jin-Shen, Wang|Guo-Qiang, Wang|Guang-Yun, Yang|Jun, Niu
PMID: 18381232
Journal: Carcinogenesis. 2008 Jun;29(6):1139-47.
Title: 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit colon cancer cell and tumor growth through activation of c-jun N-terminal kinase.
Author: Lei, Ping|Abdelrahim, Maen|Cho, Sung Dae|Liu, Shengxi|Chintharlapalli, Sudhakar|Safe, Stephen
PMID: 18460448
Journal: Biochem Biophys Res Commun. 2008 Jul 18;372(1):236-42.
Title: Morusin induces apoptosis and suppresses NF-kappaB activity in human colorectal cancer HT-29 cells.
Author: Lee, Jenq-Chang|Won, Shen-Jeu|Chao, Chien-Lin|Wu, Feng-Ling|Liu, Hsiao-Sheng|Ling, Pin|Lin, Chun-Nan|Su, Chun-Li
PMID: 18485277
Journal: Carcinogenesis. 2008 Jul;29(7):1407-14.
Title: PPARgamma is involved in mesalazine-mediated induction of apoptosis and inhibition of cell growth in colon cancer cells.
Author: Schwab, Markus|Reynders, Veerle|Loitsch, Stefan|Shastri, Yogesh M|Steinhilber, Dieter|Schroder, Oliver|Stein, Jurgen
PMID: 18544567
Journal: Oncogene. 2008 Oct 9;27(46):6012-22.
Title: A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma.
Author: Ndozangue-Touriguine, O|Sebbagh, M|Merino, D|Micheau, O|Bertoglio, J|Breard, J
PMID: 18560353
Journal: Planta Med. 2008 Sep;74(11):1357-62.
Title: Growth inhibition and apoptosis induction by tanshinone IIA in human colon adenocarcinoma cells.
Author: Su, Chin-Cheng|Chen, Guang-Wei|Kang, Jung-Cheng|Chan, Ming-Huan
PMID: 18622903
Journal: Chem Biol Interact. 2008 Nov 25;176(2-3):165-72.
Title: Anti-proliferative and pro-apoptotic effect of CPT13, a novel camptothecin analog, on human colon cancer HCT8 cell line.
Author: Wang, Li-Min|Li, Qing-Yong|Zu, Yuan-Gang|Fu, Yu-Jie|Chen, Li-Yan|Lv, Hong-Yan|Yao, Li-Ping|Jiang, Shou-Gang
PMID: 18708040
Journal: Oncology. 2008;74(3-4):229-36.
Title: Clinicopathological significance of caspase-8 and caspase-10 expression in rectal cancer.
Author: Xu, Bing|Zhou, Zong-Guang|Li, Yuan|Wang, Ling|Yang, Lie|Zhou, Bin|Liu, Hai-Yi|Song, Jun-Min|Zeng, Yu-Jian|Wang, Rong|Shen, Xiao-Gang|Sun, Xiao-Feng
PMID: 18716417
Journal: Apoptosis. 2008 Oct;13(10):1232-42.
Title: Lupulone, a hop bitter acid, activates different death pathways involving apoptotic TRAIL-receptors, in human colon tumor cells and in their derived metastatic cells.
Author: Lamy, Virginie|Roussi, Stamatiki|Chaabi, Mehdi|Gosse, Francine|Lobstein, Annelise|Raul, Francis
PMID: 18726190
Journal: Zhonghua Zhong Liu Za Zhi. 2008 Apr;30(4):245-9.
Title: [Overcoming acquired resistance to tumor necrosis factor-related apoptosis-inducing ligand by Bcl-XL small interfering RNA in human colon cancer].
Author: Zhu, Hong-Bo|Huang, Xue-Feng|Hu, Jing-Zi|Zhou, Wei|Chen, Wei|Chen, Lin-Lin|He, Chao
PMID: 18788624
Journal: Food Chem Toxicol. 2008 Dec;46(12):3753-8.
Title: Induction of apoptosis in HT-29 colon cancer cells by crude saponin from Platycodi Radix.
Author: Kim, Jae-Yong|Park, Kyoung-Wuk|Moon, Kwang-Deog|Lee, Mi-Kyung|Choi, Jina|Yee, Sung-Tae|Shim, Ki-Hwan|Seo, Kwon-Il
PMID: 18955103
Journal: Clin Cancer Res. 2008 Dec 15;14(24):8132-42.
Title: Induction of Noxa sensitizes human colorectal cancer cells expressing Mcl-1 to the small-molecule Bcl-2/Bcl-xL inhibitor, ABT-737.
Author: Okumura, Kenji|Huang, Shengbing|Sinicrope, Frank A
PMID: 19088028
Journal: Anticancer Res. 2008 Nov-Dec;28(6A):3579-92.
Title: Role of caspases in 5-FU and selenium-induced growth inhibition of colorectal cancer cells.
Author: Thant, Aye Aye|Wu, Yanyuan|Lee, Jane|Mishra, Dhruva Kumar|Garcia, Heather|Koeffler, H Phillip|Vadgama, Jaydutt V
PMID: 19189638
Journal: Cancer Lett. 2009 Jan 8;273(1):98-106.
Title: Combined treatment of Caco-2 cells with butyrate and mesalazine inhibits cell proliferation and reduces Survivin protein level.
Author: Schwab, Markus|Reynders, Veerle|Steinhilber, Dieter|Stein, Jurgen
PMID: 18774638
Journal: Oncogene. 2009 Jan 8;28(1):63-72.
Title: Combined inhibition of FLIP and XIAP induces Bax-independent apoptosis in type II colorectal cancer cells.
Author: Wilson, T R|McEwan, M|McLaughlin, K|Le Clorennec, C|Allen, W L|Fennell, D A|Johnston, P G|Longley, D B
PMID: 18820704
Journal: Chem Biol Interact. 2009 Feb 12;177(3):218-26.
Title: Mechanism of apoptosis induced by a newly synthesized derivative of macrosphelides with a thiazole side chain.
Author: Ahmed, Kanwal|Matsuya, Yuji|Nemoto, Hideo|Zaidi, Syed Faisal Haider|Sugiyama, Toshiro|Yoshihisa, Yoko|Shimizu, Tadamichi|Kondo, Takashi
PMID: 19014919
Journal: J Biol Chem. 2009 Jan 30;284(5):3354-64.
Title: Characterization of enantiomeric bile acid-induced apoptosis in colon cancer cell lines.
Author: Katona, Bryson W|Anant, Shrikant|Covey, Douglas F|Stenson, William F
PMID: 19054763
Journal: Mol Biotechnol. 2009 Mar;41(3):236-46.
Title: Comparison of caspase genes for the induction of apoptosis following gene delivery.
Author: Zhang, Xiujuan|Turner, Curlicia|Godbey, W T
PMID: 19067254
Journal: Am J Physiol Gastrointest Liver Physiol. 2009 May;296(5):G1060-8.
Title: Induction of p53 contributes to apoptosis of HCT-116 human colon cancer cells induced by the dietary compound fisetin.
Author: Lim, Do Y|Park, Jung Han Yoon
PMID: 19264955
Journal: Mol Pharmacol. 2009 Jul;76(1):192-200.
Title: S-Adenosylmethionine and methylthioadenosine inhibit cellular FLICE inhibitory protein expression and induce apoptosis in colon cancer cells.
Author: Li, Tony W H|Zhang, Qingsong|Oh, Pilsoo|Xia, Meng|Chen, Hui|Bemanian, Sean|Lastra, Natalie|Circ, Magda|Moyer, Mary Pat|Mato, Jose M|Aw, Tak Yee|Lu, Shelly C
PMID: 19372210
Journal: Biochem Pharmacol. 2009 May 1;77(9):1487-96.
Title: A rice bran polyphenol, cycloartenyl ferulate, elicits apoptosis in human colorectal adenocarcinoma SW480 and sensitizes metastatic SW620 cells to TRAIL-induced apoptosis.
Author: Kong, Carrie K L|Lam, W S|Chiu, Lawrence C M|Ooi, Vincent E C|Sun, Samuel S M|Wong, Yum-Shing
PMID: 19426686
Journal: Toxicol Lett. 2009 Jul 24;188(2):142-7.
Title: Mechanisms of thiosulfinates from Allium tuberosum L.-induced apoptosis in HT-29 human colon cancer cells.
Author: Lee, Ju-Hye|Yang, Hee-Sun|Park, Kyoung-Wuk|Kim, Jae-Yong|Lee, Mi-Kyung|Jeong, Il-Yun|Shim, Ki-Hwan|Kim, Young-Sook|Yamada, Koji|Seo, Kwon-Il
PMID: 19446247
Journal: Leuk Res. 2009 Nov;33(11):1530-8.
Title: Role of microRNA-143 in Fas-mediated apoptosis in human T-cell leukemia Jurkat cells.
Author: Akao, Yukihiro|Nakagawa, Yoshihito|Iio, Akio|Naoe, Tomoki
PMID: 19464056
Journal: Food Chem Toxicol. 2009 Sep;47(9):2157-62.
Title: Anti-proliferative effects of Lethariella zahlbruckneri extracts in human HT-29 human colon cancer cells.
Author: Ren, Mei Rong|Hur, Jae-Seoun|Kim, Jae Yong|Park, Kyoung-Wuk|Park, Seong-Chan|Seong, Chi-Nam|Jeong, Il-Yun|Byun, Myung-Woo|Lee, Mi-Kyung|Seo, Kwon-Il
PMID: 19501127
Journal: Gastroenterology. 2009 Sep;137(3):934-44, 944.e1-4.
Title: Human and mouse colon cancer utilizes CD95 signaling for local growth and metastatic spread to liver.
Author: Li, Hanchen|Fan, Xueli|Stoicov, Calin|Liu, Jian Hua|Zubair, Sharif|Tsai, Elena|Ste Marie, Ronald|Wang, Timothy C|Lyle, Stephen|Kurt-Jones, Evelyn|Houghton, Jeanmarie
PMID: 19524576
Journal: Proteomics. 2009 Jul;9(13):3535-48.
Title: Novel functional profiling approach combining reverse phase protein microarrays and human 3-D ex vivo tissue cultures: expression of apoptosis-related proteins in human colon cancer.
Author: Pirnia, Farzaneh|Pawlak, Michael|Thallinger, Gerhard G|Gierke, Berthold|Templin, Markus F|Kappeler, Andi|Betticher, Daniel C|Gloor, Beat|Borner, Markus M
PMID: 19609961
Journal: Cancer Prev Res (Phila). 2009 Aug;2(8):732-42.
Title: Regulation of colorectal cancer cell apoptosis by the n-3 polyunsaturated fatty acids Docosahexaenoic and Eicosapentaenoic.
Author: Giros, Anna|Grzybowski, Mike|Sohn, Vanessa R|Pons, Elisenda|Fernandez-Morales, Jessica|Xicola, Rosa M|Sethi, Puja|Grzybowski, Jessica|Goel, Ajay|Boland, C Richard|Gassull, Miquel A|Llor, Xavier
PMID: 19638488
Journal: Anticancer Drugs. 2009 Oct;20(9):815-21.
Title: A novel histone deacetylase inhibitor, CG0006, induces cell death through both extrinsic and intrinsic apoptotic pathways.
Author: Hwang, Jung Jin|Kim, Yong Sook|Kim, Mi Joung|Jang, Sejin|Lee, Je-Hwan|Choi, Jene|Ro, Seonggu|Hyun, Young-Lan|Lee, Jung Shin|Kim, Choung-Soo
PMID: 19644355
Journal: J Agric Food Chem. 2009 Nov 25;57(22):10573-8.
Title: Compound K induces apoptosis via CAMK-IV/AMPK pathways in HT-29 colon cancer cells.
Author: Kim, Do Yeon|Park, Min Woo|Yuan, Hai Dan|Lee, Hyo Jung|Kim, Sung Hoon|Chung, Sung Hyun
PMID: 19845353
Journal: Int J Cancer. 2010 Apr 1;126(7):1582-95.
Title: Ursodeoxycholic acid switches oxaliplatin-induced necrosis to apoptosis by inhibiting reactive oxygen species production and activating p53-caspase 8 pathway in HepG2 hepatocellular carcinoma.
Author: Lim, Sung-Chul|Choi, Jeong Eun|Kang, Ho Sung|Han, Song Iy
PMID: 19728331
Journal: Phytother Res. 2010 Jul;24(7):1019-26.
Title: The ethyl acetate extract of Phellinus linteus grown on germinated brown rice induces G0/G1 cell cycle arrest and apoptosis in human colon carcinoma HT29 cells.
Author: Park, Hye-Jin|Choi, Se Young|Hong, Se Mi|Hwang, Sung Gu|Park, Dong Ki
PMID: 19998418
Journal: Int J Cancer. 2010 Aug 15;127(4):873-80.
Title: Expression and prognostic significance of APAF-1, caspase-8 and caspase-9 in stage II/III colon carcinoma: caspase-8 and caspase-9 is associated with poor prognosis.
Author: Strater, Jorn|Herter, Ines|Merkel, Gaby|Hinz, Ulf|Weitz, Jurgen|Moller, Peter
PMID: 20013803
Journal: Apoptosis. 2010 May;15(5):597-607.
Title: The Ca(2+) channel blocker flunarizine induces caspase-10-dependent apoptosis in Jurkat T-leukemia cells.
Author: Conrad, David M|Furlong, Suzanne J|Doucette, Carolyn D|West, Kenneth A|Hoskin, David W
PMID: 20094800
Journal: Biochem Biophys Res Commun. 2010 Apr 9;394(3):774-9.
Title: Rosiglitazone enhances the radiosensitivity of p53-mutant HT-29 human colorectal cancer cells.
Author: Chiu, Shu-Jun|Hsaio, Ching-Hui|Tseng, Ho-Hsing|Su, Yu-Han|Shih, Wen-Ling|Lee, Jeng-Woei|Chuah, Jennifer Qiu-Yu
PMID: 20227390
Journal: Cancer Res. 2010 May 1;70(9):3718-29.
Title: Adipose-derived mesenchymal stem cells as stable source of tumor necrosis factor-related apoptosis-inducing ligand delivery for cancer therapy.
Author: Grisendi, Giulia|Bussolari, Rita|Cafarelli, Luigi|Petak, Istvan|Rasini, Valeria|Veronesi, Elena|De Santis, Giorgio|Spano, Carlotta|Tagliazzucchi, Mara|Barti-Juhasz, Helga|Scarabelli, Laura|Bambi, Franco|Frassoldati, Antonio|Rossi, Giulio|Casali, Christian
PMID: 20388793
Journal: Clin Cancer Res. 2010 Jul 1;16(13):3442-51.
Title: Prognostic significance of TRAIL signaling molecules in stage II and III colorectal cancer.
Author: McLornan, Donal P|Barrett, Helen L|Cummins, Robert|McDermott, Ultan|McDowell, Cliona|Conlon, Susie J|Coyle, Victoria M|Van Schaeybroeck, Sandra|Wilson, Richard|Kay, Elaine W|Longley, Daniel B|Johnston, Patrick G
PMID: 20570920
Journal: Surgery. 2010 Aug;148(2):346-53.
Title: In vitro and in vivo radiosensitization of colorectal cancer HT-29 cells by the smac mimetic JP-1201.
Author: Huerta, Sergio|Gao, Xiaohuan|Livingston, Edward H|Kapur, Payal|Sun, Haizhou|Anthony, Thomas
PMID: 20633731
Journal: Biochem Pharmacol. 2010 Nov 1;80(9):1356-64.
Title: Inhibition of cell growth and potentiation of tumor necrosis factor-alpha (TNF-alpha)-induced apoptosis by a phenanthroindolizidine alkaloid antofine in human colon cancer cells.
Author: Min, Hye-Young|Chung, Hwa-Jin|Kim, Eun-Hye|Kim, Sanghee|Park, Eun-Jung|Lee, Sang Kook
PMID: 20674553
Journal: BMC Gastroenterol. 2010 Aug 22;10:96.
Title: Fucoidan present in brown algae induces apoptosis of human colon cancer cells.
Author: Kim, Eun Ji|Park, So Young|Lee, Jae-Yong|Park, Jung Han Yoon
PMID: 20727207
Journal: Int J Oncol. 2010 Oct;37(4):1031-41.
Title: Downregulation of active caspase 8 as a mechanism of acquired TRAIL resistance in mismatch repair-proficient colon carcinoma cell lines.
Author: Van Geelen, Caroline M M|Pennarun, Bodvael|Ek, Wytske Boerma-Van|Le, Phuong T K|Spierings, Diana C J|De Vries, Elisabeth G E|De Jong, Steven
PMID: 20811726
Journal: J Biol Chem. 2010 Nov 12;285(46):35418-27.
Title: Gossypol induces death receptor-5 through activation of the ROS-ERK-CHOP pathway and sensitizes colon cancer cells to TRAIL.
Author: Sung, Bokyung|Ravindran, Jayaraj|Prasad, Sahdeo|Pandey, Manoj K|Aggarwal, Bharat B
PMID: 20837473
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2010 Sep;13(9):691-4.
Title: [Impact of fragile histidine triad gene transfection on the proliferation and apoptosis of human colorectal cancer cell].
Author: Cao, Jie|Liang, Li-yuan|Yang, Ping|Qian, Yue-jun|Wang, Hui|Sun, Zheng|Li, Wang-lin|Tan, Ming-hua
PMID: 20878579
Journal: Mol Med Rep. 2010 Jan-Feb;3(1):63-7.
Title: Sann-Joong-Kuey-Jian-Tang up-regulates the protein expression of Fas and TNF-alpha in colo 205 cells in vivo and in vitro.
Author: Cheng, Chun-Yuan|Lin, Yi-Hsiang|Su, Chin-Cheng
PMID: 21472201
Journal: J Cancer Ther. 2010 Sep;1(3):105-113.
Title: GREEN TEA POLYPHENOLS MEDIATED APOPTOSIS IN INTESTINAL EPITHELIAL CELLS BY A FADD-DEPENDENT PATHWAY.
Author: Oz, Helieh S|Ebersole, Jeffrey L
PMID: 21687829
Journal: Cancer Chemother Pharmacol. 2011 Jun;67(6):1299-312.
Title: Satraplatin (JM-216) mediates G2/M cell cycle arrest and potentiates apoptosis via multiple death pathways in colorectal cancer cells thus overcoming platinum chemo-resistance.
Author: Kalimutho, Murugan|Minutolo, Antonella|Grelli, Sandro|Formosa, Amanda|Sancesario, Giulia|Valentini, Alessandra|Federici, Giorgio|Bernardini, Sergio
PMID: 20734047
Journal: Carcinogenesis. 2011 Jan;32(1):42-51.
Title: Cisplatin and a potent platinum(IV) complex-mediated enhancement of TRAIL-induced cancer cells killing is associated with modulation of upstream events in the extrinsic apoptotic pathway.
Author: Vondalova Blanarova, Olga|Jelinkova, Iva|Szoor, Arpad|Skender, Belma|Soucek, Karel|Horvath, Viktor|Vaculova, Alena|Andera, Ladislav|Sova, Petr|Szollosi, Janos|Hofmanova, Jirina|Vereb, Gyorgy|Kozubik, Alois
PMID: 21037225
Journal: Curr Pharm Biotechnol. 2011 Feb 1;12(2):261-7.
Title: Zebrafish stem cell differentiation stage factors suppress Bcl-xL release and enhance 5-Fu-mediated apoptosis in colon cancer cells.
Author: D'Anselmi, F|Cucina, A|Biava, P M|Proietti, S|Coluccia, P|Frati, L|Bizzarri, M
PMID: 21043999
Journal: Apoptosis. 2011 Feb;16(2):184-97.
Title: Sequential caspase-2 and caspase-8 activation is essential for saikosaponin a-induced apoptosis of human colon carcinoma cell lines.
Author: Kim, Byeong Mo|Hong, Sung Hee
PMID: 21107704
Journal: J Appl Microbiol. 2011 Jan;110(1):304-13.
Title: Apoptosis-inducing effect of diketopiperazine disulfides produced by Aspergillus sp. KMD 901 isolated from marine sediment on HCT116 colon cancer cell lines.
Author: Choi, E J|Park, J-S|Kim, Y-J|Jung, J-H|Lee, J K|Kwon, H C|Yang, H O
PMID: 21122037
Journal: Oncol Rep. 2011 Feb;25(2):419-24.
Title: Death receptor 5-mediated TNFR family signaling pathways modulate gamma-humulene-induced apoptosis in human colorectal cancer HT29 cells.
Author: Lan, Yu-Hsuan|Wu, Yang-Chang|Wu, Kai-Wei|Chung, Jing-Gung|Lu, Chi-Cheng|Chen, Yuan-Liang|Wu, Tian-Shung|Yang, Jai-Sing
PMID: 21152878
Journal: Fam Cancer. 2011 Jun;10(2):245-54.
Title: Linkage to chromosome 2q32.2-q33.3 in familial serrated neoplasia (Jass syndrome).
Author: Roberts, Aedan|Nancarrow, Derek|Clendenning, Mark|Buchanan, Daniel D|Jenkins, Mark A|Duggan, David|Taverna, Darin|McKeone, Diane|Walters, Rhiannon|Walsh, Michael D|Young, Bruce W|Jass, Jeremy R|Rosty, Christophe|Gattas, Michael|Pelzer, Elise|Hopper, John
PMID: 21165777
Journal: PLoS One. 2011 Jan 17;6(1):e16241.
Title: TNFalpha cooperates with IFN-gamma to repress Bcl-xL expression to sensitize metastatic colon carcinoma cells to TRAIL-mediated apoptosis.
Author: Liu, Feiyan|Hu, Xiaolin|Zimmerman, Mary|Waller, Jennifer L|Wu, Ping|Hayes-Jordan, Andrea|Lev, Dina|Liu, Kebin
PMID: 21264227
Journal: Cancer Res. 2011 Feb 1;71(3):1156-66.
Title: EphB3 is overexpressed in non-small-cell lung cancer and promotes tumor metastasis by enhancing cell survival and migration.
Author: Ji, Xiao-Dan|Li, Guo|Feng, Yu-Xiong|Zhao, Jiang-Sha|Li, Jing-Jing|Sun, Zhi-Jian|Shi, Shuo|Deng, Yue-Zhen|Xu, Jun-Feng|Zhu, Yin-Qiu|Koeffler, H Phillip|Tong, Xiang-Jun|Xie, Dong
PMID: 21266352
Journal: BMC Cancer. 2011 Jan 27;11:39.
Title: Modulation of TRAIL resistance in colon carcinoma cells: different contributions of DR4 and DR5.
Author: van Geelen, Caroline Mm|Pennarun, Bodvael|Le, Phuong Tk|de Vries, Elisabeth Ge|de Jong, Steven
PMID: 21272366
Journal: J Agric Food Chem. 2011 Mar 23;59(6):2314-23.
Title: Citrus limonin and its glucoside inhibit colon adenocarcinoma cell proliferation through apoptosis.
Author: Chidambara Murthy, Kotamballi N|Jayaprakasha, G K|Kumar, Vinod|Rathore, Keerti S|Patil, Bhimanagouda S
PMID: 21338095
Journal: Cancer Biother Radiopharm. 2011 Feb;26(1):97-104.
Title: Aqueous extract of Curcuma aromatica induces apoptosis and G2/M arrest in human colon carcinoma LS-174-T cells independent of p53.
Author: Hu, Bing|Shen, Ke-Ping|An, Hong-Mei|Wu, Yang|Du, Qin
PMID: 21348775
Journal: Br J Surg. 2011 May;98(5):724-34.
Title: Methylation profiling of rectal cancer identifies novel markers of early-stage disease.
Author: Leong, K J|Wei, W|Tannahill, L A|Caldwell, G M|Jones, C E|Morton, D G|Matthews, G M|Bach, S P
PMID: 21360524
Journal: Carcinogenesis. 2011 May;32(5):723-31.
Title: Lipid raft-dependent death receptor 5 (DR5) expression and activation are critical for ursodeoxycholic acid-induced apoptosis in gastric cancer cells.
Author: Lim, Sung-Chul|Duong, Hong-Quan|Choi, Jeong Eun|Lee, Tae-Bum|Kang, Ju-Hee|Oh, Seung Hyun|Han, Song Iy
PMID: 21362627
Journal: Cancer Res. 2011 May 15;71(10):3625-34.
Title: Following cytochrome c release, autophagy is inhibited during chemotherapy-induced apoptosis by caspase 8-mediated cleavage of Beclin 1.
Author: Li, Hua|Wang, Peng|Sun, Quanhong|Ding, Wen-Xing|Yin, Xiao-Ming|Sobol, Robert W|Stolz, Donna B|Yu, Jian|Zhang, Lin
PMID: 21444671
Journal: Br J Pharmacol. 2011 Nov;164(5):1433-44.
Title: Methyl jasmonate down-regulates survivin expression and sensitizes colon carcinoma cells towards TRAIL-induced cytotoxicity.
Author: Raviv, Z|Zilberberg, A|Cohen, S|Reischer-Pelech, D|Horrix, C|Berger, M R|Rosin-Arbesfeld, R|Flescher, E
PMID: 21486277
Journal: Biochem Cell Biol. 2011 Jun;89(3):287-98.
Title: LYG-202 inhibits the proliferation of human colorectal carcinoma HCT-116 cells through induction of G1/S cell cycle arrest and apoptosis via p53 and p21(WAF1/Cip1) expression.
Author: Liu, Wei|Dai, Qinsheng|Lu, Na|Wei, Libin|Ha, Jun|Rong, Jingjing|Mu, Rong|You, Qidong|Li, Zhiyu|Guo, Qinglong
PMID: 21491996
Journal: Mol Cancer. 2011 Apr 25;10:46.
Title: High susceptibility of metastatic cells derived from human prostate and colon cancer cells to TRAIL and sensitization of TRAIL-insensitive primary cells to TRAIL by 4,5-dimethoxy-2-nitrobenzaldehyde.
Author: Kim, Hak-Bong|Kim, Mi-Ju|Kim, Dae-Young|Lee, Jae-Won|Bae, Jae-Ho|Kim, Dong-Wan|Kang, Chi-Dug|Kim, Sun-Hee
PMID: 21513580
Journal: Int J Colorectal Dis. 2011 Sep;26(9):1113-8.
Title: Polymorphisms of caspase 8 and caspase 9 gene and colorectal cancer susceptibility and prognosis.
Author: Theodoropoulos, George E|Gazouli, Maria|Vaiopoulou, Anna|Leandrou, Myrto|Nikouli, Sofia|Vassou, Efthimia|Kouraklis, Gregory|Nikiteas, Nikolaos
PMID: 21538054
Journal: World J Gastroenterol. 2011 Apr 28;17(16):2086-95.
Title: Effects of alpha-mangostin on apoptosis induction of human colon cancer.
Author: Watanapokasin, Ramida|Jarinthanan, Faongchat|Nakamura, Yukio|Sawasjirakij, Nitisak|Jaratrungtawee, Amornmart|Suksamrarn, Sunit
PMID: 21547127
Journal: J Med Food. 2011 Oct;14(10):1107-17.
Title: Evaluation of the effects of the flavonoid apigenin on apoptotic pathway gene expression on the colon cancer cell line (HT29).
Author: Turktekin, Mehmet|Konac, Ece|Onen, H Ilke|Alp, Ebru|Yilmaz, Akin|Menevse, Sevda
PMID: 21548803
Journal: Biomed Pharmacother. 2011 Jun;65(3):137-41.
Title: Lobaplatin suppresses proliferation and induces apoptosis in the human colorectal carcinoma cell Line LOVO in vitro.
Author: Dai, Hong-yu|Liu, Lin|Qin, Shu-kui|He, Xiang-ming|Li, Su-yi
PMID: 21612887
Journal: Eur J Pharmacol. 2011 Sep;666(1-3):173-82.
Title: The labdane diterpene sclareol (labd-14-ene-8, 13-diol) induces apoptosis in human tumor cell lines and suppression of tumor growth in vivo via a p53-independent mechanism of action.
Author: Mahaira, Louisa G|Tsimplouli, Chrisiida|Sakellaridis, Nikos|Alevizopoulos, Konstantinos|Demetzos, Costas|Han, Zhiyong|Pantazis, Panayotis|Dimas, Konstantinos
PMID: 21620827
Journal: Sci Transl Med. 2011 Jun 8;3(86):86ra50.
Title: Off-target lapatinib activity sensitizes colon cancer cells through TRAIL death receptor up-regulation.
Author: Dolloff, Nathan G|Mayes, Patrick A|Hart, Lori S|Dicker, David T|Humphreys, Robin|El-Deiry, Wafik S
PMID: 21653830
Journal: Mol Nutr Food Res. 2011 Oct;55(10):1509-22.
Title: Dicaffeoylquinic acids in Yerba mate (Ilex paraguariensis St. Hilaire) inhibit NF-kappaB nucleus translocation in macrophages and induce apoptosis by activating caspases-8 and -3 in human colon cancer cells.
Author: Puangpraphant, Sirima|Berhow, Mark A|Vermillion, Karl|Potts, Greg|Gonzalez de Mejia, Elvira
PMID: 21656672
Journal: BMC Cancer. 2011 Jul 1;11:285.
Title: Survival advantages conferred to colon cancer cells by E-selectin-induced activation of the PI3K-NFkappaB survival axis downstream of Death receptor-3.
Author: Porquet, Nicolas|Poirier, Andree|Houle, Francois|Pin, Anne-Laure|Gout, Stephanie|Tremblay, Pierre-Luc|Paquet, Eric R|Klinck, Roscoe|Auger, Francois A|Huot, Jacques
PMID: 21722370
Journal: Biosci Biotechnol Biochem. 2011;75(7):1306-11.
Title: Isoegomaketone induces apoptosis through caspase-dependent and caspase-independent pathways in human DLD1 cells.
Author: Cho, Byoung Ok|Jin, Chang Hyun|Park, Yong Dae|Ryu, Hyung Won|Byun, Myung Woo|Seo, Kwon Il|Jeong, Il Yun
PMID: 21737934
Journal: Apoptosis. 2011 Oct;16(10):1042-53.
Title: Silibinin triggers apoptotic signaling pathways and autophagic survival response in human colon adenocarcinoma cells and their derived metastatic cells.
Author: Kauntz, Henriette|Bousserouel, Souad|Gosse, Francine|Raul, Francis
PMID: 21779837
Journal: Apoptosis. 2011 Oct;16(10):1054-67.
Title: Deoxycholic and chenodeoxycholic bile acids induce apoptosis via oxidative stress in human colon adenocarcinoma cells.
Author: Ignacio Barrasa, Juan|Olmo, Nieves|Perez-Ramos, Pablo|Santiago-Gomez, Angelica|Lecona, Emilio|Turnay, Javier|Antonia Lizarbe, M
PMID: 21789651
Journal: Mol Cancer Ther. 2011 Oct;10(10):1969-81.
Title: 2-methoxy-5-amino-N-hydroxybenzamide sensitizes colon cancer cells to TRAIL-induced apoptosis by regulating death receptor 5 and survivin expression.
Author: Stolfi, Carmine|Caruso, Roberta|Franze, Eleonora|Rizzo, Angelamaria|Rotondi, Angela|Monteleone, Ivan|Fantini, Massimo Claudio|Pallone, Francesco|Monteleone, Giovanni
PMID: 21817114
Journal: Eur J Med Chem. 2011 Sep;46(9):4573-83.
Title: 6-Substituted imidazo[1,2-a]pyridines: synthesis and biological activity against colon cancer cell lines HT-29 and Caco-2.
Author: Dahan-Farkas, Nurit|Langley, Candice|Rousseau, Amanda L|Yadav, Dharmendra B|Davids, Hajierah|de Koning, Charles B
PMID: 21843907
Journal: Cancer Res. 2011 Oct 1;71(19):6270-81.
Title: Celecoxib promotes c-FLIP degradation through Akt-independent inhibition of GSK3.
Author: Chen, Shuzhen|Cao, Wei|Yue, Ping|Hao, Chunhai|Khuri, Fadlo R|Sun, Shi-Yong
PMID: 21868755
Journal: J Biol Chem. 2011 Dec 16;286(50):43123-33.
Title: GDP-mannose-4,6-dehydratase (GMDS) deficiency renders colon cancer cells resistant to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor- and CD95-mediated apoptosis by inhibiting complex II formation.
Author: Moriwaki, Kenta|Shinzaki, Shinichiro|Miyoshi, Eiji
PMID: 22027835
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2011 Oct;14(10):803-6.
Title: [Study of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptotic and inflammatory gene expressions in colon cancer cell line].
Author: Yu, Hong-bin|Zhu, Wei|Dai, Chuang
PMID: 22030783
Journal: Cell Biol Int. 2012 Mar 1;36(3):289-96.
Title: PEG-liposomal oxaliplatin induces apoptosis in human colorectal cancer cells via Fas/FasL and caspase-8.
Author: Yang, Chuang|Liu, Hai-Zhong|Fu, Zhong-Xue
PMID: 21888623
Journal: Cell Death Differ. 2012 Mar;19(3):523-33.
Title: Cell-surface galectin-3 confers resistance to TRAIL by impeding trafficking of death receptors in metastatic colon adenocarcinoma cells.
Author: Mazurek, N|Byrd, J C|Sun, Y|Hafley, M|Ramirez, K|Burks, J|Bresalier, R S
PMID: 21941373
Journal: Mol Cancer Ther. 2012 Jan;11(1):119-31.
Title: A systems biology approach identifies SART1 as a novel determinant of both 5-fluorouracil and SN38 drug resistance in colorectal cancer.
Author: Allen, Wendy L|Stevenson, Leanne|Coyle, Vicky M|Jithesh, Puthen V|Proutski, Irina|Carson, Gail|Gordon, Michael A|Lenz, Heinz-Josef D|Van Schaeybroeck, Sandra|Longley, Daniel B|Johnston, Patrick G
PMID: 22027693
Journal: Int J Oncol. 2012 Apr;40(4):1020-8.
Title: Resveratrol induces apoptosis via ROS-triggered autophagy in human colon cancer cells.
Author: Miki, Hisanori|Uehara, Norihisa|Kimura, Ayako|Sasaki, Tomo|Yuri, Takashi|Yoshizawa, Katsuhiko|Tsubura, Airo
PMID: 22218562
Journal: Cell Death Differ. 2012 Aug;19(8):1317-27.
Title: Identification of an acetylation-dependant Ku70/FLIP complex that regulates FLIP expression and HDAC inhibitor-induced apoptosis.
Author: Kerr, E|Holohan, C|McLaughlin, K M|Majkut, J|Dolan, S|Redmond, K|Riley, J|McLaughlin, K|Stasik, I|Crudden, M|Van Schaeybroeck, S|Fenning, C|O'Connor, R|Kiely, P|Sgobba, M|Haigh, D|Johnston, P G|Longley, D B
PMID: 22322857
Journal: Int J Oncol. 2012 Jun;40(6):1970-6.
Title: Ginsenoside compound K, not Rb1, possesses potential chemopreventive activities in human colorectal cancer.
Author: Wang, Chong-Zhi|Du, Guang-Jian|Zhang, Zhiyu|Wen, Xiao-Dong|Calway, Tyler|Zhen, Zhong|Musch, Mark W|Bissonnette, Marc|Chang, Eugene B|Yuan, Chun-Su
PMID: 22426808
Journal: Cancer Res Treat. 2012 Mar;44(1):32-6.
Title: Prognostic Impact of Polymorphisms in the CASPASE Genes on Survival of Patients with Colorectal Cancer.
Author: Choi, Jun Young|Kim, Jong Gwang|Lee, You Jin|Chae, Yee Soo|Sohn, Sang Kyun|Moon, Joon Ho|Kang, Byung Woog|Jung, Min Kyu|Jeon, Seong Woo|Park, Jun Seok|Choi, Gyu Seog
PMID: 22500158
Journal: Mutagenesis. 2012 Sep;27(5):559-66.
Title: CASP8 -652 6N del polymorphism and cancer risk: a meta-analysis of 30 case-control studies in 50,112 subjects.
Author: Zhang, Fan|Yang, Yuan|Guo, Cheng|Wang, Yang
PMID: 22513478
Journal: Oncol Rep. 2012 Jul;28(1):358-64.
Title: HIV-1 viral protein R (Vpr) induction of apoptosis and cell cycle arrest in multidrug-resistant colorectal cancer cells.
Author: Ma, Bo|Zhang, Hanchao|Wang, Jinhuan|Zhang, Biao|Xu, Xinnv|Cheng, Binglu
PMID: 22552851
Journal: Cancer Lett. 2012 Nov 1;324(1):98-108.
Title: Blocking p38/ERK crosstalk affects colorectal cancer growth by inducing apoptosis in vitro and in preclinical mouse models.
Author: Chiacchiera, Fulvio|Grossi, Valentina|Cappellari, Marianna|Peserico, Alessia|Simonatto, Marta|Germani, Aldo|Russo, Silvana|Moyer, Mary P|Resta, Nicoletta|Murzilli, Stefania|Simone, Cristiano
PMID: 22579651
Journal: Eur J Pharmacol. 2012 Aug 5;688(1-3):14-21.
Title: The natural alkaloid berberine targets multiple pathways to induce cell death in cultured human colon cancer cells.
Author: Chidambara Murthy, Kotamballi N|Jayaprakasha, Guddadarangavvanahally K|Patil, Bhimanagouda S
PMID: 22617025
Journal: Glycobiology. 2012 Sep;22(9):1227-35.
Title: The TF-antigen binding lectin from Sclerotium rolfsii inhibits growth of human colon cancer cells by inducing apoptosis in vitro and suppresses tumor growth in vivo.
Author: Inamdar, Shashikala R|Savanur, Mohammed Azharuddin|Eligar, Sachin M|Chachadi, Vishwanath B|Nagre, Nagaraja N|Chen, Chen|Barclays, Monica|Ingle, Aravind|Mahajan, Praveen|Borges, Anita|Shastry, Padma|Kalraiya, Rajiv D|Swamy, Bale M|Rhodes, Jonathan M|Yu, Lu
PMID: 22653662
Journal: Microb Pathog. 2012 Sep;53(3-4):147-53.
Title: Escherichia coli STb toxin induces apoptosis in intestinal epithelial cell lines.
Author: Syed, H Claudia|Dubreuil, J Daniel
PMID: 22771838
Journal: Clin Cancer Res. 2012 Oct 1;18(19):5412-26.
Title: Identification of galanin and its receptor GalR1 as novel determinants of resistance to chemotherapy and potential biomarkers in colorectal cancer.
Author: Stevenson, Leanne|Allen, Wendy L|Turkington, Richard|Jithesh, Puthen V|Proutski, Irina|Stewart, Gail|Lenz, Heinz-Josef|Van Schaeybroeck, Sandra|Longley, Daniel B|Johnston, Patrick G
PMID: 22859720
Journal: Int J Oncol. 2012 Nov;41(5):1715-22.
Title: Anticancer effects of KI-10F: a novel compound affecting apoptosis, angiogenesis and cell growth in colon cancer.
Author: Hong, Sang-Won|Jung, Kyung Hee|Choi, Myung-Joo|Kim, Da Young|Lee, Hee-Seung|Zheng, Hong-Mei|Li, Guang Yong|El-Deeb, Ibrahim M|Park, Byung Sun|Lee, So Ha|Hong, Soon-Sun
PMID: 22941304
Journal: Clin Cancer Res. 2012 Nov 1;18(21):5934-48.
Title: Stichoposide C induces apoptosis through the generation of ceramide in leukemia and colorectal cancer cells and shows in vivo antitumor activity.
Author: Yun, Seong-Hoon|Park, Eun-Seon|Shin, Sung-Won|Na, Yong-Woo|Han, Jin-Yeong|Jeong, Jin-Sook|Shastina, Valeria V|Stonik, Valentin A|Park, Joo-In|Kwak, Jong-Young
PMID: 23132899
Journal: Molecules. 2012 Dec 28;18(1):418-29.
Title: (3S)-1,2,3,4-Tetrahydro-beta-carboline-3-carboxylic acid from Cichorium endivia. L induces apoptosis of human colorectal cancer HCT-8 cells.
Author: Wang, Fu-Xin|Deng, An-Jun|Li, Ming|Wei, Jin-Feng|Qin, Hai-Lin|Wang, Ai-Ping
PMID: 23275050
Journal: Anticancer Agents Med Chem. 2013 May;13(4):532-45.
Title: A small-molecule inhibitor, 5'-O-tritylthymidine, targets FAK and Mdm-2 interaction, and blocks breast and colon tumorigenesis in vivo.
Author: Golubovskaya, Vita M|Palma, Nadia L|Zheng, Min|Ho, Baotran|Magis, Andrew|Ostrov, David|Cance, William G
PMID: 22292771
Journal: Gut. 2013 Jun;62(6):882-9.
Title: A novel myokine, secreted protein acidic and rich in cysteine (SPARC), suppresses colon tumorigenesis via regular exercise.
Author: Aoi, Wataru|Naito, Yuji|Takagi, Tomohisa|Tanimura, Yuko|Takanami, Yoshikazu|Kawai, Yukari|Sakuma, Kunihiro|Hang, Liu Po|Mizushima, Katsura|Hirai, Yasuko|Koyama, Ryota|Wada, Sayori|Higashi, Akane|Kokura, Satoshi|Ichikawa, Hiroshi|Yoshikawa, Toshikazu
PMID: 22851666
Journal: Integr Cancer Ther. 2013 May;12(3):248-56.
Title: Fermentation product of soybean, black bean, and green bean mixture induces apoptosis in a wide variety of cancer cells.
Author: Chia, Jean-San|Du, Jia-Ling|Wu, Ming-Shiou|Hsu, Wei-Bin|Chiang, Chun-Pin|Sun, Andy|Lu, John Jenn-Yenn|Wang, Won-Bo
PMID: 23027830
Journal: Gastroenterology. 2013 Feb;144(2):283-93.
Title: Complex roles of caspases in the pathogenesis of inflammatory bowel disease.
Author: Becker, Christoph|Watson, Alastair J|Neurath, Markus F
PMID: 23219999
Journal: Mol Biol Cell. 2013 Feb;24(4):465-73.
Title: beta-Catenin-dependent lysosomal targeting of internalized tumor necrosis factor-alpha suppresses caspase-8 activation in apoptosis-resistant colon cancer cells.
Author: Han, Jinbo|Sridevi, Priya|Ramirez, Michael|Ludwig, Kirsten J|Wang, Jean Y J
PMID: 23264463
Journal: Mol Cancer Res. 2013 Mar;11(3):207-18.
Title: Nuclear expression of beta-catenin promotes RB stability and resistance to TNF-induced apoptosis in colon cancer cells.
Author: Han, Jinbo|Soletti, Rossana C|Sadarangani, Anil|Sridevi, Priya|Ramirez, Michael E|Eckmann, Lars|Borges, Helena L|Wang, Jean Y J
PMID: 23339186
Journal: Cancer Biol Ther. 2013 May;14(5):436-49.
Title: Identification of novel compounds that enhance colon cancer cell sensitivity to inflammatory apoptotic ligands.
Author: Chopra, Avijeet S|Kuratnik, Anton|Scocchera, Eric W|Wright, Dennis L|Giardina, Charles
PMID: 23377828
Journal: PLoS One. 2013;8(2):e57218.
Title: Curcumin enhances the effect of chemotherapy against colorectal cancer cells by inhibition of NF-kappaB and Src protein kinase signaling pathways.
Author: Shakibaei, Mehdi|Mobasheri, Ali|Lueders, Cora|Busch, Franziska|Shayan, Paviz|Goel, Ajay
PMID: 23451189
Journal: Phytomedicine. 2013 Apr 15;20(6):528-36.
Title: Cytotoxicity and modes of action of four naturally occuring benzophenones: 2,2',5,6'-tetrahydroxybenzophenone, guttiferone E, isogarcinol and isoxanthochymol.
Author: Kuete, Victor|Tchakam, Patricia D|Wiench, Benjamin|Ngameni, Bathelemy|Wabo, Hippolyte K|Tala, Michel F|Moungang, Marlyse L|Ngadjui, Bonaventure T|Murayama, Tetsuya|Efferth, Thomas
PMID: 23507522
Journal: Mol Med Rep. 2013 May;7(5):1487-93.
Title: Sann-Joong-Kuey-Jian-Tang inhibits hepatocellular carcinoma Hep-G2 cell proliferation by increasing TNF-alpha, Caspase-8, Caspase- 3 and Bax but by decreasing TCTP and Mcl-1 expression in vitro.
Author: Chen, Yao-Li|Yan, Meng-Yi|Chien, Su-Yu|Kuo, Shou-Jen|Chen, Dar-Ren|Cheng, Chun-Yuan|Su, Chin-Cheng
PMID: 23525225
Journal: J Physiol Pharmacol. 2013 Feb;64(1):115-23.
Title: Evaluation of apoptotic activity of new condensed pyrazole derivatives.
Author: Toton, E|Ignatowicz, E|Bernard, M K|Kujawski, J|Rybczynska, M
PMID: 23568979
Journal: FEBS J. 2013 Jul;280(14):3244-55.
Title: SERPINA3K induces apoptosis in human colorectal cancer cells via activating the Fas/FasL/caspase-8 signaling pathway.
Author: Yao, Yachao|Li, Lei|Huang, Xuan|Gu, Xiaoqiong|Xu, Zumin|Zhang, Yang|Huang, Lijun|Li, Shuai|Dai, Zhiyu|Li, Cen|Zhou, Ti|Cai, Weibin|Yang, Zhonghan|Gao, Guoquan|Yang, Xia
PMID: 23615374
Journal: Med Oncol. 2013;30(3):565.
Title: Association between main Caspase gene polymorphisms and the susceptibility and prognosis of colorectal cancer.
Author: Wu, Zhiwei|Li, Ye|Li, Shuying|Zhu, Lin|Li, Guangxiao|Yu, Zhifu|Zhao, Xiaojuan|Ge, Jie|Cui, Binbin|Dong, Xinshu|Tian, Suli|Hu, Fulan|Zhao, Yashuang
PMID: 23715747
Journal: J Ethnopharmacol. 2013 Aug 26;149(1):245-53.
Title: Cytotoxicity and modes of action of four Cameroonian dietary spices ethno-medically used to treat cancers: Echinops giganteus, Xylopia aethiopica, Imperata cylindrica and Piper capense.
Author: Kuete, Victor|Sandjo, Louis P|Wiench, Benjamin|Efferth, Thomas
PMID: 23827757
Journal: PLoS One. 2013 Jul 2;8(7):e67577.
Title: Genetic polymorphisms of the CASP8 gene promoter may not be associated with colorectal cancer in Han Chinese from southwest China.
Author: Xiao, Mei-Sheng|Chang, Le|Li, Wen-Liang|Du, Yong-Sheng|Pan, Yue|Zhang, Deng-Feng|Wen, Yu|Luo, Juan|Li, Xiao-Yan|Yao, Yong-Gang
PMID: 23844036
Journal: Toxicol Lett. 2013 Oct 24;222(2):139-45.
Title: Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactive oxygen species.
Author: Zhou, Jin|Li, Pu|Xue, Xiaofeng|He, Songbing|Kuang, Yuting|Zhao, Hong|Chen, Shaoji|Zhi, Qiaoming|Guo, Xiaobo
PMID: 23916687
Journal: Food Chem Toxicol. 2013 Oct;60:439-47.
Title: Anti-cancer effect and apoptosis induction of cordycepin through DR3 pathway in the human colonic cancer cell HT-29.
Author: Lee, Seung Yuan|Debnath, Trishna|Kim, Si-Kwan|Lim, Beong Ou
PMID: 23941773
Journal: Int J Mol Sci. 2013 Aug 12;14(8):16600-16.
Title: Cadmium modifies the cell cycle and apoptotic profiles of human breast cancer cells treated with 5-fluorouracil.
Author: Asara, Yolande|Marchal, Juan A|Carrasco, Esther|Boulaiz, Houria|Solinas, Giuliana|Bandiera, Pasquale|Garcia, Maria A|Farace, Cristiano|Montella, Andrea|Madeddu, Roberto
PMID: 23941782
Journal: Biochimie. 2013 Nov;95(11):2157-67.
Title: Antitumour activity on extrinsic apoptotic targets of the triterpenoid maslinic acid in p53-deficient Caco-2 adenocarcinoma cells.
Author: Reyes-Zurita, Fernando J|Rufino-Palomares, Eva E|Medina, Pedro P|Leticia Garcia-Salguero, E|Peragon, Juan|Cascante, Marta|Lupianez, Jose A
PMID: 23973282
Journal: Int J Oncol. 2013 Nov;43(5):1560-8.
Title: Receptor-like protein tyrosine phosphatase kappa negatively regulates the apoptosis of prostate cancer cells via the JNK pathway.
Author: Sun, Ping-Hui|Ye, Lin|Mason, Malcolm D|Jiang, Wen G
PMID: 24002526
Journal: Biotechnol Lett. 2013 Dec;35(12):2031-8.
Title: Plant-derived mAbs have effective anti-cancer activities by increasing ganglioside expression in colon cancers.
Author: Ryu, Jae-Sung|Lee, Ju-Taek|Lim, Malg-Um|Hwang, Mi-Ran|Hwang, Kyung-A|Cho, Young-Ho|Lee, Jeong-Hwan|Ko, Kisung|Choo, Young-Kug
PMID: 24078119
Journal: World J Gastroenterol. 2013 Nov 14;19(42):7374-88.
Title: 1,3-Bis(2-chloroethyl)-1-nitrosourea enhances the inhibitory effect of resveratrol on 5-fluorouracil sensitive/resistant colon cancer cells.
Author: Das, Dipon|Preet, Ranjan|Mohapatra, Purusottam|Satapathy, Shakti Ranjan|Kundu, Chanakya Nath
PMID: 24259968
Journal: Cell Biochem Biophys. 2014 Apr;68(3):597-609.
Title: The novel heterocyclic trioxirane [(1,3,5-tris oxiran-2-yl)methyl)-1,3,5-triazinane-2,4,6-trione (TATT)] exhibits a better anticancer effect than platinum-based chemotherapy by induction of apoptosis and curcumin further enhances its chemosensitivity.
Author: Su, Chun-Li|Wang, Ying-Ti|Chang, Mu-Hsin|Fang, Kang|Chen, Kwunmin
PMID: 24078402
Journal: J Biol Chem. 2014 Jan 31;289(5):2978-91.
Title: Novel piperazine-based compounds inhibit microtubule dynamics and sensitize colon cancer cells to tumor necrosis factor-induced apoptosis.
Author: Chopra, Avijeet|Anderson, Amy|Giardina, Charles
PMID: 24338023
Journal: PLoS One. 2014 Jan 21;9(1):e85538.
Title: Association between CASP8 -652 6N del polymorphism (rs3834129) and colorectal cancer risk: results from a multi-centric study.
Author: Pardini, Barbara|Verderio, Paolo|Pizzamiglio, Sara|Nici, Carmela|Maiorana, Maria Valeria|Naccarati, Alessio|Vodickova, Ludmila|Vymetalkova, Veronika|Veneroni, Silvia|Daidone, Maria Grazia|Ravagnani, Fernando|Bianchi, Tiziana|Bujanda, Luis|Carracedo, Angel
PMID: 24465592
Journal: Biochem Pharmacol. 2014 Mar 15;88(2):178-88.
Title: Role of Bcl-xL/Beclin-1 in interplay between apoptosis and autophagy in oxaliplatin and bortezomib-induced cell death.
Author: Kim, Seog-Young|Song, Xinxin|Zhang, Lin|Bartlett, David L|Lee, Yong J
PMID: 24486574
Journal: PLoS One. 2014 Feb 3;9(2):e87925.
Title: CASP8 -652 6N del polymorphism contributes to colorectal cancer susceptibility: evidence from a meta-analysis.
Author: Peng, Qiliu|Lao, Xianjun|Tang, Weizhong|Chen, Zhiping|Li, Ruolin|Wang, Jian|Deng, Yan|Li, Taijie|Qin, Xue|Li, Shan
PMID: 24498403
Journal: Tumour Biol. 2014 Jun;35(6):5307-14.
Title: Dihydroartemisinin induces apoptosis in colorectal cancer cells through the mitochondria-dependent pathway.
Author: Lu, Min|Sun, Luhaoran|Zhou, Jin|Yang, Jing
PMID: 24519064
Journal: Int J Mol Sci. 2014 Feb 17;15(2):2722-37.
Title: Mechanisms underlying apoptosis-inducing effects of Kaempferol in HT-29 human colon cancer cells.
Author: Lee, Hyun Sook|Cho, Han Jin|Yu, Rina|Lee, Ki Won|Chun, Hyang Sook|Park, Jung Han Yoon
PMID: 24549175
Journal: Oncol Rep. 2014 Apr;31(4):1788-94.
Title: Tangeretin, a citrus polymethoxyflavonoid, induces apoptosis of human gastric cancer AGS cells through extrinsic and intrinsic signaling pathways.
Author: Dong, Yang|Cao, Aili|Shi, Jianrong|Yin, Peihao|Wang, Li|Ji, Guang|Xie, Jianqun|Wu, Dazheng
PMID: 24573532
Journal: Cell Death Dis. 2014 Feb 27;5:e1085.
Title: The LEF1/CYLD axis and cIAPs regulate RIP1 deubiquitination and trigger apoptosis in selenite-treated colorectal cancer cells.
Author: Wu, P|Shi, K J|An, J J|Ci, Y L|Li, F|Hui, K Y|Yang, Y|Xu, C M
PMID: 24577083
Journal: Oncol Lett. 2014 May;7(5):1728-1732.
Title: Laminarin-induced apoptosis in human colon cancer LoVo cells.
Author: Ji, Chen-Feng|Ji, Yu-Bin
PMID: 24765209
Journal: Chem Biol Drug Des. 2014 Jul;84(1):36-43.
Title: Antibody against N-terminal domain of phospholipid scramblase 1 induces apoptosis in colorectal cancer cells through the intrinsic apoptotic pathway.
Author: Chen, Chun-Yu|Chen, Jinn-Shiun|Chou, Yeh-Pin|Kuo, Yung-Bin|Fan, Chung-Wei|Chan, Err-Cheng
PMID: 24766818
Journal: Epigenomics. 2014 Apr;6(2):179-91.
Title: DNA methylation changes in genes frequently mutated in sporadic colorectal cancer and in the DNA repair and Wnt/beta-catenin signaling pathway genes.
Author: Farkas, Sanja A|Vymetalkova, Veronika|Vodickova, Ludmila|Vodicka, Pavel|Nilsson, Torbjorn K
PMID: 24811787
Journal: Mol Cancer Res. 2014 Sep;12(9):1225-32.
Title: BaxDelta2 promotes apoptosis through caspase-8 activation in microsatellite-unstable colon cancer.
Author: Zhang, Honghong|Lin, Yuting|Manas, Adriana|Zhao, Yu|Denning, Mitchell F|Ma, Li|Xiang, Jialing
PMID: 24842234
Journal: Mol Cancer. 2014 May 26;13:124.
Title: microRNA-139-5p exerts tumor suppressor function by targeting NOTCH1 in colorectal cancer.
Author: Zhang, Lijing|Dong, Yujuan|Zhu, Nana|Tsoi, Ho|Zhao, Zengren|Wu, Chung Wah|Wang, Kunning|Zheng, Shu|Ng, Simon Sm|Chan, Francis Kl|Sung, Joseph Jy|Yu, Jun
PMID: 24885920
Journal: J Cell Biochem. 2014 Nov;115(11):1888-99.
Title: Expression of survivin and p53 modulates honokiol-induced apoptosis in colorectal cancer cells.
Author: Lai, Ying-Jiun|Lin, Chien-I|Wang, Chia-Lin|Chao, Jui-I
PMID: 24905183
Journal: Food Chem Toxicol. 2014 Sep;71:51-9.
Title: Ilimaquinone induces death receptor expression and sensitizes human colon cancer cells to TRAIL-induced apoptosis through activation of ROS-ERK/p38 MAPK-CHOP signaling pathways.
Author: Do, Minh Truong|Na, MinKyun|Kim, Hyung Gyun|Khanal, Tilak|Choi, Jae Ho|Jin, Sun Woo|Oh, Seok Hoon|Hwang, In Hyun|Chung, Young Chul|Kim, Hee Suk|Jeong, Tae Cheon|Jeong, Hye Gwang
PMID: 24930757
Journal: Cancer Biomark. 2014;14(4):233-40.
Title: A novel inflammatory regulator TIPE2 inhibits TLR4-mediated development of colon cancer via caspase-8.
Author: Li, Xue-Mei|Su, Jing-Ran|Yan, Shi-Ping|Cheng, Zhao-Ling|Yang, Ting-Ting|Zhu, Qiang
PMID: 24934366
Journal: J Dig Dis. 2014 Sep;15(9):491-500.
Title: Silencing of JMJD2B induces cell apoptosis via mitochondria-mediated and death receptor-mediated pathway activation in colorectal cancer.
Author: Sun, Bei Bei|Fu, Lin Na|Wang, Yun Qian|Gao, Qin Yan|Xu, Jie|Cao, Zhi Jun|Chen, Ying Xuan|Fang, Jing Yuan
PMID: 24957706
Journal: Oncol Rep. 2014 Oct;32(4):1341-6.
Title: Phloroglucinol induces apoptosis via apoptotic signaling pathways in HT-29 colon cancer cells.
Author: Kang, Mi-Hye|Kim, In-Hye|Nam, Taek-Jeong
PMID: 25070748
Journal: Asian Pac J Cancer Prev. 2014;15(15):6321-6.
Title: Activation of JNK/p38 pathway is responsible for alpha-methyl-n-butylshikonin induced mitochondria-dependent apoptosis in SW620 human colorectal cancer cells.
Author: Wang, Hai-Bing|Ma, Xiao-Qiong
PMID: 25124618
Journal: Environ Toxicol Pharmacol. 2014 Sep;38(2):489-501.
Title: NCI in vitro and in silico anticancer screen, cell cycle pertubation and apoptosis-inducing potential of new acylated, benzylidene and isopropylidene derivatives of andrographolide.
Author: Wong, Charng Choon|Sagineedu, Sreenivasa Rao|Sumon, Shariful Hasan|Sidik, Shiran Mohamad|Phillips, Roger|Lajis, Nordin H|Stanslas, Johnson
PMID: 25168151
Journal: BMC Complement Altern Med. 2014 Oct 24;14:412.
Title: Hederagenin from the leaves of ivy (Hedera helix L.) induces apoptosis in human LoVo colon cells through the mitochondrial pathway.
Author: Liu, Bao-Xin-Zi|Zhou, Jin-Yong|Li, Yu|Zou, Xi|Wu, Jian|Gu, Jun-Fei|Yuan, Jia-Rui|Zhao, Bing-Jie|Feng, Liang|Jia, Xiao-Bin|Wang, Rui-Ping
PMID: 25342273
Journal: Cell Death Dis. 2014 Oct 30;5:e1504.
Title: Role of AMP-activated protein kinase in cross-talk between apoptosis and autophagy in human colon cancer.
Author: Song, X|Kim, S-Y|Zhang, L|Tang, D|Bartlett, D L|Kwon, Y T|Lee, Y J
PMID: 25356873
Journal: MAbs. 2014;6(6):1560-70.
Title: Multivalent nanobodies targeting death receptor 5 elicit superior tumor cell killing through efficient caspase induction.
Author: Huet, Heather A|Growney, Joseph D|Johnson, Jennifer A|Li, Jing|Bilic, Sanela|Ostrom, Lance|Zafari, Mohammad|Kowal, Colleen|Yang, Guizhi|Royo, Axelle|Jensen, Michael|Dombrecht, Bruno|Meerschaert, Kris R A|Kolkman, Joost A|Cromie, Karen D|Mosher, Rebecca|Ga
PMID: 25484045
Journal: Mol Pharm. 2015 Jan 5;12(1):287-97.
Title: Nucleolar targeting by platinum: p53-independent apoptosis follows rRNA inhibition, cell-cycle arrest, and DNA compaction.
Author: Peterson, Erica J|Menon, Vijay R|Gatti, Laura|Kipping, Ralph|Dewasinghe, Dilhara|Perego, Paola|Povirk, Lawrence F|Farrell, Nicholas P
PMID: 25407898
Journal: J Agric Food Chem. 2015 Jan 14;63(1):150-9.
Title: Water stress proteins from Nostoc commune Vauch. exhibit anti-colon cancer activities in vitro and in vivo.
Author: Guo, Songjia|Shan, Shuhua|Jin, Xiaoting|Li, Zongwei|Li, Zhuoyu|Zhao, Liangqi|An, Quan|Zhang, Wei
PMID: 25524246
Journal: J Ginseng Res. 2015 Jan;39(1):22-8.
Title: Effect of sun ginseng potentiation on epirubicin and paclitaxel-induced apoptosis in human cervical cancer cells.
Author: Lin, Yingjia|Jiang, Dan|Li, Yang|Han, Xinye|Yu, Di|Park, Jeong Hill|Jin, Ying-Hua
PMID: 25535473
Journal: J Cell Physiol. 2015 Sep;230(9):2281-98.
Title: Nexavar/Stivarga and viagra interact to kill tumor cells.
Author: Tavallai, Mehrad|Hamed, Hossein A|Roberts, Jane L|Cruickshanks, Nichola|Chuckalovcak, John|Poklepovic, Andrew|Booth, Laurence|Dent, Paul
PMID: 25704960
Journal: Int J Mol Sci. 2015 Mar 9;16(3):5386-99.
Title: Different apoptotic pathways activated by oxaliplatin in primary astrocytes vs. colo-rectal cancer cells.
Author: Zanardelli, Matteo|Micheli, Laura|Nicolai, Raffaella|Failli, Paola|Ghelardini, Carla|Di Cesare Mannelli, Lorenzo
PMID: 25761243
Journal: Clin Cancer Res. 2015 Jul 15;21(14):3230-3240.
Title: HDAC Inhibition Overcomes Acute Resistance to MEK Inhibition in BRAF-Mutant Colorectal Cancer by Downregulation of c-FLIPL.
Author: Carson, Robbie|Celtikci, Basak|Fenning, Cathy|Javadi, Arman|Crawford, Nyree|Carbonell, Lucia Perez|Lawler, Mark|Longley, Daniel B|Johnston, Patrick G|Van Schaeybroeck, Sandra
PMID: 25813020
Journal: J Hematol Oncol. 2015 Mar 15;8:26.
Title: Aloperine executes antitumor effects against multiple myeloma through dual apoptotic mechanisms.
Author: Wang, He|Yang, Shu|Zhou, Hong|Sun, Mingna|Du, Lingran|Wei, Minyan|Luo, Meixia|Huang, Jingzhu|Deng, Hongzhu|Feng, Yinghong|Huang, Jun|Zhou, Yi
PMID: 25886453
Journal: Int J Oncol. 2015;46(6):2670-8.
Title: The flavonoid morin from Moraceae induces apoptosis by modulation of Bcl-2 family members and Fas receptor in HCT 116 cells.
Author: Hyun, Hwang-Bo|Lee, Won Sup|Go, Se-Il|Nagappan, Arulkumar|Park, Cheol|Han, Min Ho|Hong, Su Hyun|Kim, Gonsup|Kim, Gi Young|Cheong, Jaehun|Ryu, Chung Ho|Shin, Sung Chul|Choi, Yung Hyun
PMID: 25892545
Journal: Cell Death Dis. 2015 Apr 23;6:e1729.
Title: Loss of caspase-3 sensitizes colon cancer cells to genotoxic stress via RIP1-dependent necrosis.
Author: Brown, M F|Leibowitz, B J|Chen, D|He, K|Zou, F|Sobol, R W|Beer-Stolz, D|Zhang, L|Yu, J
PMID: 25906152
Journal: World J Gastroenterol. 2015 May 28;21(20):6194-205.
Title: Gambogic acid induces apoptosis and inhibits colorectal tumor growth via mitochondrial pathways.
Author: Huang, Guang-Ming|Sun, Yu|Ge, Xin|Wan, Xin|Li, Chun-Bo
PMID: 26034354
Journal: BMC Complement Altern Med. 2015 Jun 30;15:205.
Title: Water extract of brewers' rice induces apoptosis in human colorectal cancer cells via activation of caspase-3 and caspase-8 and downregulates the Wnt/beta-catenin downstream signaling pathway in brewers' rice-treated rats with azoxymethane-induced colon c
Author: Tan, Bee Ling|Norhaizan, Mohd Esa|Huynh, Ky|Heshu, Sulaiman Rahman|Yeap, Swee Keong|Hazilawati, Hamzah|Roselina, Karim
PMID: 26122204
Journal: Oxid Med Cell Longev. 2015;2015:154164.
Title: Impact of Procyanidins from Different Berries on Caspase 8 Activation in Colon Cancer.
Author: Minker, Carole|Duban, Livine|Karas, Daniel|Jarvinen, Paivi|Lobstein, Annelise|Muller, Christian D
PMID: 26180579
Journal: Acta Pharmacol Sin. 2015 Sep;36(9):1074-84.
Title: New benzimidazole acridine derivative induces human colon cancer cell apoptosis in vitro via the ROS-JNK signaling pathway.
Author: Chen, Kang|Chu, Bi-zhu|Liu, Feng|Li, Bin|Gao, Chun-mei|Li, Lu-lu|Sun, Qin-sheng|Shen, Zhi-fa|Jiang, Yu-yang
PMID: 26235743
Journal: Int J Mol Sci. 2015 Aug 17;16(8):19401-18.
Title: Methyl Sartortuoate Inhibits Colon Cancer Cell Growth by Inducing Apoptosis and G2/M-Phase Arrest.
Author: Lan, Qiusheng|Li, Shoufeng|Lai, Wei|Xu, Heyang|Zhang, Yang|Zeng, Yujie|Lan, Wenjian|Chu, Zhonghua
PMID: 26287184
Journal: Arch Pharm (Weinheim). 2015 Oct;348(10):730-42.
Title: Synthesis of Tolmetin Hydrazide-Hydrazones and Discovery of a Potent Apoptosis Inducer in Colon Cancer Cells.
Author: Kucukguzel, S Guniz|Koc, Derya|Cikla-Suzgun, Pelin|Ozsavci, Derya|Bingol-Ozakpinar, Ozlem|Mega-Tiber, Pinar|Orun, Oya|Erzincan, Pinar|Sag-Erdem, Safiye|Sahin, Fikrettin
PMID: 26287512
Journal: PLoS One. 2015 Sep 21;10(9):e0138607.
Title: Aberrant Apoptotic Response of Colorectal Cancer Cells to Novel Nucleoside Analogues.
Author: Harmse, Leonie|Dahan-Farkas, Nurit|Panayides, Jenny-Lee|van Otterlo, Willem|Penny, Clement
PMID: 26390405
Journal: Oncotarget. 2015 Dec 29;6(42):44437-51.
Title: Anti-cancer effect of bee venom on colon cancer cell growth by activation of death receptors and inhibition of nuclear factor kappa B.
Author: Zheng, Jie|Lee, Hye Lim|Ham, Young Wan|Song, Ho Sueb|Song, Min Jong|Hong, Jin Tae
PMID: 26561202
Journal: Am J Cancer Res. 2015 Oct 15;5(10):3174-85. eCollection 2015.
Title: Necrostatin-1 reduces intestinal inflammation and colitis-associated tumorigenesis in mice.
Author: Liu, Zhen-Yu|Wu, Bo|Guo, Yun-Shan|Zhou, Ying-Hui|Fu, Zhi-Guang|Xu, Bao-Qing|Li, Jiang-Hua|Jing, Lin|Jiang, Jian-Li|Tang, Juan|Chen, Zhi-Nan
PMID: 26693068
Journal: Front Pharmacol. 2016 Jan 28;6:313.
Title: Mechanism of Action of the Novel Nickel(II) Complex in Simultaneous Reactivation of the Apoptotic Signaling Networks Against Human Colon Cancer Cells.
Author: Samie, Nima|Haerian, Batoul Sadat|Muniandy, Sekaran|Marlina, Anita|Kanthimathi, M S|Abdullah, Norbani B|Ahmadian, Gholamreza|Aziddin, Raja E R
PMID: 26858642
Journal: J Cell Biochem. 2016 May;117(5):1078-91.
Title: TRAIL-Induced Caspase Activation Is a Prerequisite for Activation of the Endoplasmic Reticulum Stress-Induced Signal Transduction Pathways.
Author: Lee, Dae-Hee|Sung, Ki Sa|Guo, Zong Sheng|Kwon, William Taehyung|Bartlett, David L|Oh, Sang Cheul|Kwon, Yong Tae|Lee, Yong J
PMID: 26212606
Journal: J Cell Biochem. 2016 May;117(5):1262-72.
Title: Crataegus azarolus Leaves Induce Antiproliferative Activity, Cell Cycle Arrest, and Apoptosis in Human HT-29 and HCT-116 Colorectal Cancer Cells.
Author: Mustapha, Nadia|Pinon, Aline|Limami, Youness|Simon, Alain|Ghedira, Kamel|Hennebelle, Thierry|Chekir-Ghedira, Leila
PMID: 26495895
Journal: Anticancer Agents Med Chem. 2016;16(8):1055-1065.
Title: Guarana a Caffeine-Rich Food Increases Oxaliplatin Sensitivity of Colorectal HT-29 Cells by Apoptosis Pathway Modulation.
Author: Cadona, Francine Carla|Machado, Alencar Kolinski|Azzolin, Veronica Farina|Barbisan, Fernanda|Dornelles, Eduardo Bortoluzzi|Glanzner, Werner|Goncalves, Paulo Bayard Dias|Assmann, Charles Elias|Ribeiro, Euler Esteves|Cruz, Ivana Beatrice Manica da
PMID: 26673759
Journal: PLoS One. 2016 Jan 11;11(1):e0146178.
Title: Maslinic Acid, a Natural Triterpene, Induces a Death Receptor-Mediated Apoptotic Mechanism in Caco-2 p53-Deficient Colon Adenocarcinoma Cells.
Author: Reyes-Zurita, Fernando J|Rufino-Palomares, Eva E|Garcia-Salguero, Leticia|Peragon, Juan|Medina, Pedro P|Parra, Andres|Cascante, Marta|Lupianez, Jose A
PMID: 26751572
Journal: J Biol Chem. 2016 Mar 11;291(11):5960-70.
Title: The Deubiquitinase Inhibitor PR-619 Sensitizes Normal Human Fibroblasts to Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-mediated Cell Death.
Author: Crowder, Roslyn N|Dicker, David T|El-Deiry, Wafik S
PMID: 26757822
Journal: Oncotarget. 2016 Feb 9;7(6):7161-78.
Title: The probiotic Propionibacterium freudenreichii as a new adjuvant for TRAIL-based therapy in colorectal cancer.
Author: Cousin, Fabien J|Jouan-Lanhouet, Sandrine|Theret, Nathalie|Brenner, Catherine|Jouan, Elodie|Le Moigne-Muller, Gwenaelle|Dimanche-Boitrel, Marie-Therese|Jan, Gwenael
PMID: 26771233
Journal: Oncotarget. 2016 Jan 26;7(4):3709-25.
Title: Cooperative TRAIL production mediates IFNalpha/Smac mimetic-induced cell death in TNFalpha-resistant solid cancer cells.
Author: Roesler, Stefanie|Eckhardt, Ines|Wolf, Sebastian|Fulda, Simone
PMID: 26788912
Journal: Tumour Biol. 2016 Aug;37(8):10097-105.
Title: Long non-coding RNA AK027294 involves in the process of proliferation, migration, and apoptosis of colorectal cancer cells.
Author: Niu, Hui|Hu, Zhaoyang|Liu, Hui|Hu, Guoliang|Yang, Bo|Wu, Shixiu|Li, Fang
PMID: 26820130
Journal: Chin J Integr Med. 2016 Jan 29. pii: 10.1007/s11655-015-2108-3.
Title: Synergistic anti-tumor activity and mechanisms of total glycosides from Cimicifuga dahurica in combination with cisplatin.
Author: Zhang, Lei-Lei|Si, Jian-Yong|Zhang, Li-Jing|Xiao-Wei, Huo|Lin, Li|Li, Ru-Yi|Chen, Dan|Cao, Li
PMID: 26825081
Journal: Planta Med. 2016 Mar;82(4):312-21.
Title: Thymoquinone from Nigella sativa Seeds Promotes the Antitumor Activity of Noncytotoxic Doses of Topotecan in Human Colorectal Cancer Cells in Vitro.
Author: Khalife, Rana|Hodroj, Mohammad Hassan|Fakhoury, Rajaa|Rizk, Sandra
PMID: 26848703
Journal: J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Mar 1;1014:17-23.
Title: Metabolomics study on the antitumor effect of marine natural compound flexibilide in HCT-116 colon cancer cell line.
Author: Gao, Dan|Wang, Yini|Xie, Weiyi|Yang, Ti|Jiang, Yuyang|Guo, Yuewei|Guan, Jin|Liu, Hongxia
PMID: 26859520
Journal: Pharmacol Res. 2016 May;107:66-78.
Title: SRJ09, a promising anticancer drug lead: Elucidation of mechanisms of antiproliferative and apoptogenic effects and assessment of in vivo antitumor efficacy.
Author: Wong, Charng Choon|Lim, Siang Hui|Sagineedu, Sreenivasa Rao|Lajis, Nordin Haji|Stanslas, Johnson
PMID: 26940565
Journal: J Ethnopharmacol. 2016 May 26;184:107-18.
Title: Synergistic cytotoxic effects of combined delta-tocotrienol and jerantinine B on human brain and colon cancers.
Author: Abubakar, Ibrahim Babangida|Lim, Kuan-Hon|Kam, Toh-Seok|Loh, Hwei-San
PMID: 26947901
Journal: Toxicol Appl Pharmacol. 2016 Jun 1;300:1-12.
Title: Goniothalamin prevents the development of chemically induced and spontaneous colitis in rodents and induces apoptosis in the HT-29 human colon tumor cell line.
Author: Vendramini-Costa, Debora Barbosa|Alcaide, Antonio|Pelizzaro-Rocha, Karin Juliane|Talero, Elena|Avila-Roman, Javier|Garcia-Maurino, Sofia|Pilli, Ronaldo Aloise|de Carvalho, Joao Ernesto|Motilva, Virginia
PMID: 27016270
Journal: Colloids Surf B Biointerfaces. 2016 Jul 1;143:499-510.
Title: Polyphenol stabilized colloidal gold nanoparticles from Abutilon indicum leaf extract induce apoptosis in HT-29 colon cancer cells.
Author: Mata, Rani|Nakkala, Jayachandra Reddy|Sadras, Sudha Rani
PMID: 27038915
Journal: J Biol Chem. 2016 May 27;291(22):11843-51.
Title: Cleavage by Caspase 8 and Mitochondrial Membrane Association Activate the BH3-only Protein Bid during TRAIL-induced Apoptosis.
Author: Huang, Kai|Zhang, Jingjing|O'Neill, Katelyn L|Gurumurthy, Channabasavaiah B|Quadros, Rolen M|Tu, Yaping|Luo, Xu
PMID: 27053107
Journal: PLoS One. 2016 Apr 12;11(4):e0152652.
Title: Cycloart-24-ene-26-ol-3-one, a New Cycloartane Isolated from Leaves of Aglaia exima Triggers Tumour Necrosis Factor-Receptor 1-Mediated Caspase-Dependent Apoptosis in Colon Cancer Cell Line.
Author: Leong, Kok Hoong|Looi, Chung Yeng|Loong, Xe-Min|Cheah, Foo Kit|Supratman, Unang|Litaudon, Marc|Mustafa, Mohd Rais|Awang, Khalijah
PMID: 27070314
Journal: Biomol Ther (Seoul). 2016 May 1;24(3):320-7.
Title: Columbianadin Inhibits Cell Proliferation by Inducing Apoptosis and Necroptosis in HCT116 Colon Cancer Cells.
Author: Kang, Ji In|Hong, Ji-Young|Choi, Jae Sue|Lee, Sang Kook
PMID: 27098859
Journal: Cancer Res. 2016 Sep 1;76(17):5103-14.
Title: Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
Author: Fehringer, Gordon|Kraft, Peter|Pharoah, Paul D|Eeles, Rosalind A|Chatterjee, Nilanjan|Schumacher, Fredrick R|Schildkraut, Joellen M|Lindstrom, Sara|Brennan, Paul|Bickeboller, Heike|Houlston, Richard S|Landi, Maria Teresa|Caporaso, Neil|Risch, Angela|Amin
PMID: 27197191
Journal: Oncol Rep. 2016 Jul;36(1):205-14.
Title: Hwang-Heuk-San induces apoptosis in HCT116 human colorectal cancer cells through the ROS-mediated activation of caspases and the inactivation of the PI3K/Akt signaling pathway.
Author: Lee, Moon Hee|Hong, Su-Hyun|Park, Cheol|Kim, Gi-Young|Leem, Sun-Hee|Choi, Sung Hyun|Keum, Young-Sam|Hyun, Jin Won|Kwon, Taeg Kyu|Hong, Sang Hoon|Choi, Yung Hyun
PMID: 27221553
Journal: Toxicol Lett. 2016 Aug 22;257:84-96.
Title: Isoledene from Mesua ferrea oleo-gum resin induces apoptosis in HCT 116 cells through ROS-mediated modulation of multiple proteins in the apoptotic pathways: A mechanistic study.
Author: Asif, Muhammad|Shafaei, Armaghan|Jafari, Seyedeh Fatemeh|Mohamed, Shazmin Kithur|Ezzat, Mohammed Oday|Abdul Majid, Aman Shah|Oon, Chern Ein|Petersen, Sven H|Kono, Koji|Abdul Majid, Amin Malik Shah
PMID: 27268964
Journal: Chem Biol Interact. 2016 Aug 25;256:198-208.
Title: Isolation and characterization of alborixin from Streptomyces scabrisporus: A potent cytotoxic agent against human colon (HCT-116) cancer cells.
Author: Shah, Aabid Manzoor|Wani, Abubakar|Qazi, Parvaiz H|Rehman, Shakeel-U|Mushtaq, Saleem|Ali, Shiekh Abid|Hussain, Aehtesham|Shah, Aiyatullah|Qazi, Asif Khurshid|Makhdoomi, Ubaid Sharif|Hamid, Abid|Kumar, Ajay
PMID: 27378626
Journal: Folia Histochem Cytobiol. 2016;54(2):99-107.
Title: Myenteric plexuses atrophy in the vicinity of colorectal cancer tissue is not caused by apoptosis or necrosis.
Author: Kozlowska, Anna|Kwiatkowski, Przemyslaw|Oponowicz, Agnieszka|Majewski, Mariusz|Kmiec, Zbigniew|Godlewski, Janusz
PMID: 27439439
Journal: Tumour Biol. 2016 Oct;37(10):13345-13353.
Title: The anti-oncogenic influence of ellagic acid on colon cancer cells in leptin-enriched microenvironment.
Author: Yousef, Amany I|El-Masry, Omar S|Yassin, Eman H
PMID: 27460082
Journal: Sci Rep. 2016 Aug 4;6:30816.
Title: Ceramide mediates FasL-induced caspase 8 activation in colon carcinoma cells to enhance FasL-induced cytotoxicity by tumor-specific cytotoxic T lymphocytes.
Author: Coe, Genevieve L|Redd, Priscilla S|Paschall, Amy V|Lu, Chunwan|Gu, Lilly|Cai, Houjian|Albers, Thomas|Lebedyeva, Iryna O|Liu, Kebin
PMID: 27487939
Journal: BMC Cancer. 2016 Aug 9;16:618.
Title: Prognostic relevance of caspase 8 -652 6N InsDel and Asp302His polymorphisms for breast cancer.
Author: Kuhlmann, J D|Bankfalvi, A|Schmid, K W|Callies, R|Kimmig, R|Wimberger, P|Siffert, W|Bachmann, H S
PMID: 27507139
Journal: Biochem Biophys Res Commun. 2016 Sep 30;478(4):1515-20.
Title: mTOR inhibition sensitizes ONC201-induced anti-colorectal cancer cell activity.
Author: Jin, Zhe-Zhu|Wang, Wei|Fang, Di-Long|Jin, Yong-Jun
PMID: 27565731
Journal: Sci Rep. 2016 Sep 13;6:32979.
Title: Crocetin exploits p53-induced death domain (PIDD) and FAS-associated death domain (FADD) proteins to induce apoptosis in colorectal cancer.
Author: Ray, Pallab|Guha, Deblina|Chakraborty, Juni|Banerjee, Shuvomoy|Adhikary, Arghya|Chakraborty, Samik|Das, Tanya|Sa, Gaurisankar
PMID: 27622714
Journal: Cancer Sci. 2016 Dec;107(12):1877-1887.
Title: Effect of AKT3 expression on MYC- and caspase-8-dependent apoptosis caused by polo-like kinase inhibitors in HCT 116 cells.
Author: Nonomiya, Yuma|Noguchi, Kohji|Tanaka, Noritaka|Kasagaki, Takahiro|Katayama, Kazuhiro|Sugimoto, Yoshikazu
PMID: 27699933
Journal: BMC Complement Altern Med. 2016 Nov 18;16(1):473.
Title: Evaluation of anti-tumorigenic activity of BP3B against colon cancer with patient-derived tumor xenograft model.
Author: Kim, Hye-Youn|Kim, Jinhee|Ha Thi, Huyen Trang|Bang, Ok-Sun|Lee, Won-Suk|Hong, Suntaek
PMID: 27863496
Journal: Integr Med Res. 2016 Dec;5(4):284-292.
Title: Water extract of Galla Rhois with steaming process enhances apoptotic cell death in human colon cancer cells.
Author: Yim, Nam-Hui|Gu, Min Jung|Hwang, Youn-Hwan|Cho, Won-Kyung|Ma, Jin Yeul
PMID: 28462130
Journal: J Tradit Chin Med. 2016 Dec;36(6):760-7.
Title: Effect of ethanol extract of HPRS, a Traditional Chinese Medicine formula, on HCT116 cell Line.
Author: Lu, Jun|Xu, Jun|Shi, Qin
PMID: 29949709
Journal: J Gastrointest Cancer. 2017 Jun;48(2):156-163.
Title: siRNA-Mediated Silencing of HMGA2 Induces Apoptosis and Cell Cycle Arrest in Human Colorectal Carcinoma.
Author: Esmailzadeh, Sahar|Mansoori, Behzad|Mohammadi, Ali|Shanehbandi, Dariush|Baradaran, Behzad
PMID: 27629422
Journal: Oncol Rep. 2017 Feb;37(2):1132-1140.
Title: Apigenin induces both intrinsic and extrinsic pathways of apoptosis in human colon carcinoma HCT-116 cells.
Author: Wang, Bo|Zhao, Xin-Huai
PMID: 27959417
Journal: Oncol Rep. 2017 Jan;37(1):571-578.
Title: miR-20a-directed regulation of BID is associated with the TRAIL sensitivity in colorectal cancer.
Author: Huang, Guanli|Chen, Xiangjian|Cai, Yefeng|Wang, Xiaobo|Xing, Chungen
PMID: 28004114
Journal: PLoS One. 2017 Jan 9;12(1):e0168989.
Title: CIL-102-Induced Cell Cycle Arrest and Apoptosis in Colorectal Cancer Cells via Upregulation of p21 and GADD45.
Author: Huang, Wen-Shih|Kuo, Yi-Hung|Kuo, Hsing-Chun|Hsieh, Meng-Chiao|Huang, Cheng-Yi|Lee, Ko-Chao|Lee, Kam-Fai|Shen, Chien-Heng|Tung, Shui-Yi|Teng, Chih-Chuan
PMID: 28068431
Journal: Biochem Cell Biol. 2017 Feb;95(1):99-109.
Title: Bovine lactoferrin and lactoferricin exert antitumor activities on human colorectal cancer cells (HT-29) by activating various signaling pathways.
Author: Jiang, Rulan|Lonnerdal, Bo
PMID: 28169560
Journal: Oncol Rep. 2017 Apr;37(4):2079-2086.
Title: A novel cycloartane triterpenoid from Cimicifuga induces apoptotic and autophagic cell death in human colon cancer HT-29 cells.
Author: Dai, Xiaoli|Liu, Jing|Nian, Yin|Qiu, Ming-Hua|Luo, Ying|Zhang, Jihong
PMID: 28260002
Journal: Curr Pharm Des. 2017;23(41):6358-6365.
Title: Synthesis and Characterization of a New Benzoindole Derivative with Apoptotic Activity Against Colon Cancer Cells.
Author: Hajiaghaalipour, Fatemeh|Faraj, Fadhil L|Bagheri, Elham|Ali, Hapipah M|Abdulla, Mahmood Ameen|Majid, Nazia A
PMID: 28325143
Journal: Tumour Biol. 2017 Mar;39(3):1010428317695019.
Title: Apoptosis mediated chemosensitization of tumor cells to 5-fluorouracil on supplementation of fish oil in experimental colon carcinoma.
Author: Rani, Isha|Sharma, Bhoomika|Kumar, Sandeep|Kaur, Satinder|Agnihotri, Navneet
PMID: 28349837
Journal: J Exp Med. 2017 Jun 5;214(6):1655-1662.
Title: Regression of apoptosis-resistant colorectal tumors by induction of necroptosis in mice.
Author: He, Gui-Wei|Gunther, Claudia|Thonn, Veronika|Yu, Yu-Qiang|Martini, Eva|Buchen, Barbara|Neurath, Markus F|Sturzl, Michael|Becker, Christoph
PMID: 28476895
Journal: Nutr Res. 2017 May;41:36-46.
Title: Secretion metabolites of probiotic yeast, Pichia kudriavzevii AS-12, induces apoptosis pathways in human colorectal cancer cell lines.
Author: Saber, Amir|Alipour, Beitollah|Faghfoori, Zeinab|Mousavi Jam, Ali|Yari Khosroushahi, Ahmad
PMID: 28477945
Journal: Cell Death Dis. 2017 May 25;8(5):e2815.
Title: Furanodienone induces G0/G1 arrest and causes apoptosis via the ROS/MAPKs-mediated caspase-dependent pathway in human colorectal cancer cells: a study in vitro and in vivo.
Author: Jiang, Ying|Wang, Xiaoqin|Hu, Daode
PMID: 28542135
Journal: BMC Genomics. 2017 May 30;18(1):421.
Title: Genome-wide network-based pathway analysis of CSF t-tau/Abeta1-42 ratio in the ADNI cohort.
Author: Cong, Wang|Meng, Xianglian|Li, Jin|Zhang, Qiushi|Chen, Feng|Liu, Wenjie|Wang, Ying|Cheng, Sipu|Yao, Xiaohui|Yan, Jingwen|Kim, Sungeun|Saykin, Andrew J|Liang, Hong|Shen, Li
PMID: 28558704
Journal: Pharm Res. 2017 Sep;34(9):1849-1856.
Title: The Cardiotoxic Mechanism of Doxorubicin (DOX) and Pegylated Liposomal DOX in Mice Bearing C-26 Colon Carcinoma: a Study Focused on microRNA Role for Toxicity Assessment of New Formulations.
Author: Razavi-Azarkhiavi, Kamal|Jaafari, Mahmoud Reza|Abnous, Khalil|Razavi, Bibi Marjan|Jafarian, Amir Hossein|Hassani, Faezeh Vahdati|Shirani, Kobra|Karimi, Gholamreza
PMID: 28560697
Journal: J Cell Biol. 2017 Jul 3;216(7):2201-2216.
Title: Caspase-8 controls the secretion of inflammatory lysyl-tRNA synthetase in exosomes from cancer cells.
Author: Kim, Sang Bum|Kim, Hye Rim|Park, Min Chul|Cho, Seongmin|Goughnour, Peter C|Han, Daeyoung|Yoon, Ina|Kim, YounHa|Kang, Taehee|Song, Eunjoo|Kim, Pilhan|Choi, Hyosun|Mun, Ji Young|Song, Chihong|Lee, Sangmin|Jung, Hyun Suk|Kim, Sunghoon
PMID: 28611052
Journal: J Ethnopharmacol. 2017 Jul 31;207:19-29.
Title: 8-methoxypsoralen reduces AKT phosphorylation, induces intrinsic and extrinsic apoptotic pathways, and suppresses cell growth of SK-N-AS neuroblastoma and SW620 metastatic colon cancer cells.
Author: Bartnik, Magdalena|Slawinska-Brych, Adrianna|Zurek, Aleksandra|Kandefer-Szerszen, Martyna|Zdzisinska, Barbara
PMID: 28627461
Journal: Integr Med Res. 2017 Jun;6(2):179-189.
Title: Induction of apoptosis by Dae-Hwang-Mok-Dan-Tang in HCT-116 colon cancer cells through activation of caspases and inactivation of the phosphatidylinositol 3-kinase/Akt signaling.
Author: Park, Cheol|Hong, Su Hyun|Choi, Yung Hyun
PMID: 28664141
Journal: J Med Food. 2017 Jul;20(7):659-666.
Title: Plant Sterol Esters in Extruded Food Model Inhibits Colon Carcinogenesis by Suppressing Inflammation and Stimulating Apoptosis.
Author: Sadek, Nur Fathonah|Yuliana, Nancy Dewi|Prangdimurti, Endang|Priosoeryanto, Bambang Pontjo|Budijanto, Slamet
PMID: 28692412
Journal: Front Pharmacol. 2017 Sep 12;8:640.
Title: Morin Inhibits Proliferation of SW480 Colorectal Cancer Cells by Inducing Apoptosis Mediated by Reactive Oxygen Species Formation and Uncoupling of Warburg Effect.
Author: Sithara, Thomas|Arun, K B|Syama, H P|Reshmitha, T R|Nisha, P
PMID: 28955240
Journal: Cell Death Dis. 2017 Oct 5;8(10):e3086.
Title: A novel acridine derivative, LS-1-10 inhibits autophagic degradation and triggers apoptosis in colon cancer cells.
Author: Fu, Wan|Li, Xue|Lu, Xiaopeng|Zhang, Luyao|Li, Ran|Zhang, Nan|Liu, Shan|Yang, Xin|Wang, Yue|Zhao, Ying|Meng, Xiangbao|Zhu, Wei-Guo
PMID: 28981103
Journal: World J Gastroenterol. 2017 Oct 7;23(37):6854-6867.
Title: Association of insertion-deletions polymorphisms with colorectal cancer risk and clinical features.
Author: Marques, Diego|Ferreira-Costa, Layse Raynara|Ferreira-Costa, Lorenna Larissa|Correa, Romualdo da Silva|Borges, Aline Maciel Pinheiro|Ito, Fernanda Ribeiro|Ramos, Carlos Cesar de Oliveira|Bortolin, Raul Hernandes|Luchessi, Andre Ducati|Ribeiro-Dos-Santos,
PMID: 29085228
Journal: Turk J Med Sci. 2017 Nov 13;47(5):1549-1554.
Title: Polymorphisms of cancer-related genes and risk of multipleprimary malignancies involving colorectal cancer
Author: Cao, Peiguo|Yu, Li|Wu, Anshan|Li, Jingjing|Liu, Ling|Liu, Chunlan|Zhou, Jianda|Cao, Ke|Guo, Chengxian
PMID: 29151331
Journal: J Zhejiang Univ Sci B. 2017 Dec.;18(12):1101-1112.
Title: Apoptosis induction of colorectal cancer cells HTL-9 in vitro by the transformed products of soybean isoflavones by Ganoderma lucidum.
Author: Cui, Mei-Lin|Yang, Huan-Yi|He, Guo-Qing
PMID: 29204990
Journal: Cell Death Dis. 2017 Dec 14;8(12):3218.
Title: ROS-induced cleavage of NHLRC2 by caspase-8 leads to apoptotic cell death in the HCT116 human colon cancer cell line.
Author: Nishi, Kensuke|Iwaihara, Yuri|Tsunoda, Toshiyuki|Doi, Keiko|Sakata, Toshifumi|Shirasawa, Senji|Ishikura, Shuhei
PMID: 29242562
Journal: World J Gastroenterol. 2017 Dec 28;23(48):8533-8543.
Title: Analysis of 12 variants in the development of gastric and colorectal cancers.
Author: Cavalcante, Giovanna C|Amador, Marcos At|Ribeiro Dos Santos, Andre M|Carvalho, Darlen C|Andrade, Roberta B|Pereira, Esdras Eb|Fernandes, Marianne R|Costa, Danielle F|Santos, Ney Pc|Assumpcao, Paulo P|Ribeiro Dos Santos, Andrea|Santos, Sidney
PMID: 29358861
Journal: Mol Carcinog. 2018 Mar;57(3):347-360.
Title: Antitumor activity of Lepidium latifolium and identification of the epithionitrile 1-cyano-2,3-epithiopropane as its major active component.
Author: Conde-Rioll, Maria|Gajate, Consuelo|Fernandez, Jose J|Villa-Pulgarin, Janny A|Napolitano, Jose G|Norte, Manuel|Mollinedo, Faustino
PMID: 29073716
Journal: Mol Cancer Res. 2018 Mar;16(3):378-389.
Title: Targeting CDK1 and MEK/ERK Overcomes Apoptotic Resistance in BRAF-Mutant Human Colorectal Cancer.
Author: Zhang, Peng|Kawakami, Hisato|Liu, Weizhen|Zeng, Xiangyu|Strebhardt, Klaus|Tao, Kaixiong|Huang, Shengbing|Sinicrope, Frank A
PMID: 29233910
Journal: J Agric Food Chem. 2018 Jan 24;66(3):602-612.
Title: Zerumbone, a Cyclic Sesquiterpene from Zingiber zerumbet Induces Apoptosis, Cell Cycle Arrest, and Antimigratory Effects in SW480 Colorectal Cancer Cells.
Author: Sithara, Thomas|Dhanya, B P|Arun, K B|Sini, Suresh|Dan, Mathew|Kokkuvayil Vasu, Radhakrishnan|Nisha, P
PMID: 29276946
Journal: J Cancer. 2018 Jan 1;9(1):41-53.
Title: Modulated electro-hyperthermia induced loco-regional and systemic tumor destruction in colorectal cancer allografts.
Author: Vancsik, Tamas|Kovago, Csaba|Kiss, Eva|Papp, Edina|Forika, Gertrud|Benyo, Zoltan|Meggyeshazi, Nora|Krenacs, Tibor
PMID: 29290768
Journal: Biochem Biophys Res Commun. 2018 Jan 29;496(1):18-24.
Title: BaxDelta2 sensitizes colorectal cancer cells to proteasome inhibitor-induced cell death.
Author: Manas, Adriana|Chen, Wenjing|Nelson, Adam|Yao, Qi|Xiang, Jialing
PMID: 29291406
Journal: Cancer Biomark. 2018;21(4):899-908.
Title: Synergistic role of Caspase-8 and Caspase-3 expressions: Prognostic and predictive biomarkers in colorectal cancer.
Author: Yao, Qiang|Wang, Weimin|Jin, Jun|Min, Ke|Yang, Jian|Zhong, Yubing|Xu, Chunni|Deng, Jianliang|Zhou, Yan
PMID: 29355114
Journal: Phytother Res. 2018 Jun;32(6):1108-1118.
Title: Drug-like dietary vanilloids induce anticancer activity through proliferation inhibition and regulation of bcl-related apoptotic proteins.
Author: Mai, Chun-Wai|Kang, Yew-Beng|Nadarajah, Vishna Devi|Hamzah, Ahmad Sazali|Pichika, Mallikarjuna Rao
PMID: 29464796
Journal: J Cell Physiol. 2018 Sep;233(9):7134-7142.
Title: Fisetin mediated apoptotic cell death in parental and Oxaliplatin/irinotecan resistant colorectal cancer cells in vitro and in vivo.
Author: Jeng, Long-Bin|Kumar Velmurugan, Bharath|Chen, Ming-Cheng|Hsu, Hsi-Hsien|Ho, Tsung-Jung|Day, Cecilia-Hsuan|Lin, Yueh-Min|Padma, V Vijaya|Tu, Chuan-Chou|Huang, Chih-Yang
PMID: 29574877
Journal: Drug Des Devel Ther. 2018 Mar 29;12:657-671.
Title: The apoptotic effects of Brucea javanica fruit extract against HT29 cells associated with p53 upregulation and inhibition of NF-kappaB translocation.
Author: Bagheri, Elham|Hajiaghaalipour, Fatemeh|Nyamathulla, Shaik|Salehen, Nur'Ain
PMID: 29636600
Journal: Food Funct. 2018 Apr 25;9(4):2145-2157.
Title: The inhibitory effect of Manuka honey on human colon cancer HCT-116 and LoVo cell growth. Part 1: the suppression of cell proliferation, promotion of apoptosis and arrest of the cell cycle.
Author: Afrin, Sadia|Giampieri, Francesca|Gasparrini, Massimiliano|Forbes-Hernandez, Tamara Y|Cianciosi, Danila|Reboredo-Rodriguez, Patricia|Amici, Adolfo|Quiles, Jose L|Battino, Maurizio
PMID: 29645049
Journal: Histochem Cell Biol. 2018 Jul;150(1):77-82.
Title: Detection of pro-apoptotic Bax2 proteins in the human cerebellum.
Author: Manas, Adriana|Davis, Aislinn|Lamerand, Sydney|Xiang, Jialing
PMID: 29663074
Journal: Biochim Biophys Acta Mol Basis Dis. 2018 Aug;1864(8):2600-2609.
Title: Nogo-B (Reticulon-4B) functions as a negative regulator of the apoptotic pathway through the interaction with c-FLIP in colorectal cancer cells.
Author: Kawaguchi, Nao|Tashiro, Keitaro|Taniguchi, Kohei|Kawai, Masaru|Tanaka, Keitaro|Okuda, Junji|Hayashi, Michihiro|Uchiyama, Kazuhisa
PMID: 29684585
Journal: Med Sci Monit. 2018 Apr 26;24:2550-2561.
Title: Effects of Recombinant Circularly Permuted Tumor Necrosis Factor (TNF)-Related Apoptosis-Inducing Ligand (TRAIL) (Recombinant Mutant Human TRAIL) in Combination with 5-Fluorouracil in Human Colorectal Cancer Cell Lines HCT116 and SW480.
Author: Sun, Tongyou|Zhu, Tienian|Liang, Xiujun|Yang, Shifang|Zhao, Ruijing
PMID: 29695684
Journal: Apoptosis. 2018 May 12. pii: 10.1007/s10495-018-1457-8.
Title: Resveratrol analogue, (E)-N-(2-(4-methoxystyryl) phenyl) furan-2-carboxamide induces G2/M cell cycle arrest through the activation of p53-p21(CIP1/WAF1) in human colorectal HCT116 cells.
Author: Cheah, Foo Kit|Leong, Kok Hoong|Thomas, Noel Francis|Chin, Hui Kee|Ariffin, Azhar|Awang, Khalijah
PMID: 29754265
Journal: Asian Pac J Cancer Prev. 2018 May 26;19(5):1277-1280.
Title: Expression Level of Caspase Genes in Colorectal Cancer
Author: Asadi, Milad|Shanehbandi, Dariush|Asvadi Kermani, Touraj|Sanaat, Zohreh|Zafari, Venus|Hashemzadeh, Shahriyar
PMID: 29801534
Journal: BMC Cancer. 2018 May 29;18(1):602.
Title: Knock-down of LRP/LR promotes apoptosis in early and late stage colorectal carcinoma cells via caspase activation.
Author: Vania, Leila|Rebelo, Thalia M|Ferreira, Eloise|Weiss, Stefan F T
PMID: 29843646
Journal: Food Nutr Res. 2018 May 11;62. pii: 1384.
Title: Genistein and daidzein induce apoptosis of colon cancer cells by inhibiting the accumulation of lipid droplets.
Author: Liang, Yu-Si|Qi, Wen-Tao|Guo, Weiqun|Wang, Chun-Ling|Hu, Ze-Bin|Li, Ai-Ke
PMID: 29849534
Journal: Phytother Res. 2018 Jun 7.
Title: Reactive oxygen species-mediated phosphorylation of p38 signaling is critically involved in apoptotic effect of Tanshinone I in colon cancer cells.
Author: Kim, Dong Hee|Shin, Eun Ah|Kim, Bonglee|Shim, Bum Sang|Kim, Sung-Hoon
PMID: 29876988
Journal: Asian Pac J Cancer Prev. 2018 Jun 25;19(6):1457-1464.
Title: Calotroposid A: a Glycosides Terpenoids from Calotropis gigantea Induces Apoptosis of Colon Cancer WiDr Cells through Cell Cycle Arrest G2/M and Caspase 8 Expression
Author: Mutiah, Roihatul|Widyawaruyanti, Aty|Sukardiman, Sukardiman
PMID: 29936715
Journal: Front Pharmacol. 2018 Jun 12;9:629.
Title: Cell Cycle Arrest and Apoptosis in HT-29 Cells Induced by Dichloromethane Fraction From Toddalia asiatica (L.) Lam.
Author: Li, Xun|Qiu, Zidong|Jin, Qinghao|Chen, Guilin|Guo, Mingquan
PMID: 29950999
Journal: Oncol Lett. 2018 Jul;16(1):769-774.
Title: IL-33 notably inhibits the growth of colon cancer cells.
Author: Chen, Xuhui|Lu, Kuanchang|Timko, Noah J|Weir, Dylan M|Zhu, Ziwen|Qin, Chenglu|Mann, Jeffery D|Bai, Qian|Xiao, Huaping|Nicholl, Michael B|Wakefield, Mark R|Fang, Yujiang
PMID: 29963144
Journal: J Biomed Res. 2018 Jul 27.
Title: A meta-analysis of caspase-8 -652 6N del polymorphism and digestive tract cancer risk.
Author: Du, Haina|Song, Guoxin|Fang, Mingzhi|Shu, Yong-Qian|Zhao, Xin|Zhu, Ling-Jun
PMID: 30057371
Journal: Mol Pharmacol. 2018 Oct;94(4):1187-1196.
Title: Bortezomib Targets Sp Transcription Factors in Cancer Cells.
Author: Karki, Keshav|Harishchandra, Sneha|Safe, Stephen
PMID: 30115673
Journal: Food Res Int. 2018 Nov;113:298-308.
Title: Comparison of phytochemical profiles and antiproliferative activities of different proanthocyanidins fractions from Choerospondias axillaris fruit peels.
Author: Li, Qian|Liu, Chengmei|Li, Ti|McClements, David Julian|Fu, Yinxin|Liu, Jiyan
PMID: 30195524
Journal: Oncol Lett. 2018 Oct;16(4):4640-4648.
Title: Total ginsenosides of Chinese ginseng induces cell cycle arrest and apoptosis in colorectal carcinoma HT-29 cells.
Author: Li, Ting|Sun, Wan|Dong, Xiaoqiao|Yu, Wenhua|Cai, Jianyong|Yuan, Qiang|Shan, Letian|Efferth, Thomas
PMID: 30197678
Journal: Gastroenterology. 2018 Sep 26. pii: S0016-5085(18)35036-4.
Title: Intestinal Inflammation and Dysregulated Immunity in Patients with Inherited Caspase-8 Deficiency.
Author: Lehle, Anna S|Farin, Henner F|Marquardt, Benjamin|Michels, Birgitta E|Magg, Thomas|Li, Yue|Liu, Yanshan|Ghalandary, Maryam|Lammens, Katja|Hollizeck, Sebastian|Rohlfs, Meino|Hauck, Fabian|Conca, Raffaele|Walz, Christoph|Weiss, Batia|Lev, Atar|Simon, Amos J
PMID: 30267714
Journal: Res Pharm Sci. 2018 Oct;13(5):404-412.
Title: Cytotoxic effect of methanolic extract, alkaloid and terpenoid fractions of Stachys pilifera against HT-29 cell line.
Author: Kokhdan, Esmaeel Panahi|Sadeghi, Hossein|Ghafoori, Hossin|Sadeghi, Heibatollah|Danaei, Nazanin|Javadian, Hamedreza|Aghamaali, Mahmoud Reza
PMID: 30271442
Journal: Eur J Pharmacol. 2018 Oct 16. pii: S0014-2999(18)30591-0.
Title: Isoliquiritigenin-mediated p62/SQSTM1 induction regulates apoptotic potential through attenuation of caspase-8 activation in colorectal cancer cells.
Author: Jin, Hao|Seo, Geom Seog|Lee, Sung Hee
PMID: 30339814
Journal: Biomed Res Int. 2018 Sep 27;2018:2548378.
Title: alpha-Hederin Arrests Cell Cycle at G2/M Checkpoint and Promotes Mitochondrial Apoptosis by Blocking Nuclear Factor-kappaB Signaling in Colon Cancer Cells.
Author: Sun, Dongdong|Shen, Weixing|Zhang, Feng|Fan, Huisen|Tan, Jiani|Li, Liu|Xu, Changliang|Zhang, Haibin|Yang, Ye|Cheng, Haibo
PMID: 30363706