Primary Site >> Colorectal Cancer

Gene >> CASP7

Journal: Cancer Res. 2000 Aug 1;60(15):4270-6.
Title: Characterization of bile salt-induced apoptosis in colon cancer cell lines.
Author: Schlottman, K|Wachs, F P|Krieg, R C|Kullmann, F|Scholmerich, J|Rogler, G
PMID: 10945641
Journal: Hum Pathol. 2001 May;32(5):461-7.
Title: Caspase 7 downregulation as an immunohistochemical marker of colonic carcinoma.
Author: Palmerini, F|Devilard, E|Jarry, A|Birg, F|Xerri, L
PMID: 11381362
Journal: Biochem Biophys Res Commun. 2003 Jul 11;306(4):954-8.
Title: Dephosphorylation of p53 during cell death by N-alpha-tosyl-L-phenylalanyl chloromethyl ketone.
Author: Kim, Karam|Choi, Kyung Hee|Fu, Ya-Min|Meadows, Gary G|Joe, Cheol O
PMID: 12821135
Journal: Cancer Res. 2003 Aug 1;63(15):4368-74.
Title: Regulation of caspase expression and apoptosis by adenomatous polyposis coli.
Author: Chen, Tingan|Yang, Ivana|Irby, Rosalyn|Shain, Kenneth H|Wang, Hong Gang|Quackenbush, John|Coppola, Domenico|Cheng, Jin Q|Yeatman, Timothy J
PMID: 12907606
Journal: Oncogene. 2003 Sep 11;22(39):8048-52.
Title: Inactivating mutations of CASPASE-7 gene in human cancers.
Author: Soung, Young Hwa|Lee, Jong Woo|Kim, Hong Sug|Park, Won Sang|Kim, Su Young|Lee, Jong Heun|Park, Jik Young|Cho, Yong Gu|Kim, Chang Jae|Park, Yong Gyu|Nam, Suk Woo|Jeong, Seong Whan|Kim, Sang Ho|Lee, Jung Young|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 12970753
Journal: J Biol Chem. 2004 Oct 29;279(44):45875-86.
Title: Orexins acting at native OX(1) receptor in colon cancer and neuroblastoma cells or at recombinant OX(1) receptor suppress cell growth by inducing apoptosis.
Author: Rouet-Benzineb, Patricia|Rouyer-Fessard, Christiane|Jarry, Anne|Avondo, Virgile|Pouzet, Cecile|Yanagisawa, Masashi|Laboisse, Christian|Laburthe, Marc|Voisin, Thierry
PMID: 15310763
Journal: J Biol Chem. 2004 Aug 27;279(35):36680-8.
Title: Oncogenic Ras promotes butyrate-induced apoptosis through inhibition of gelsolin expression.
Author: Klampfer, Lidija|Huang, Jie|Sasazuki, Takehiko|Shirasawa, Senji|Augenlicht, Leonard
PMID: 15213223
Journal: J Biol Chem. 2004 Jul 16;279(29):30358-68. Epub 2004 May 3.
Title: Requirement of histone deacetylase activity for signaling by STAT1.
Author: Klampfer, Lidija|Huang, Jie|Swaby, Laurie-Anne|Augenlicht, Leonard
PMID: 15123634
Journal: Ann Surg Oncol. 2004 Feb;11(2):192-6.
Title: Deleted in oral cancer-1 expression upregulates proapoptosis elements in microsatellite-unstable human colorectal cancer.
Author: Sotsky Kent, Tara|Yuan, Ziqiang|Miller, Agnes|Weber, Thomas K
PMID: 14761923
Journal: Oncogene. 2006 Oct 26;25(50):6582-94.
Title: Bak functionally complements for loss of Bax during p14ARF-induced mitochondrial apoptosis in human cancer cells.
Author: Hemmati, P G|Guner, D|Gillissen, B|Wendt, J|von Haefen, C|Chinnadurai, G|Dorken, B|Daniel, P T
PMID: 16847458
Journal: Carcinogenesis. 2007 Oct;28(10):2207-17.
Title: Aspirin blocks proliferation in colon cells by inducing a G1 arrest and apoptosis through activation of the checkpoint kinase ATM.
Author: Luciani, M Gloria|Campregher, Christoph|Gasche, Christoph
PMID: 17510082
Journal: Am J Physiol Gastrointest Liver Physiol. 2008 May;294(5):G1235-44.
Title: CUGBP2 downregulation by prostaglandin E2 protects colon cancer cells from radiation-induced mitotic catastrophe.
Author: Natarajan, Gopalan|Ramalingam, Satish|Ramachandran, Ilangovan|May, Randal|Queimado, Lurdes|Houchen, Courtney W|Anant, Shrikant
PMID: 18325984
Journal: Gastroenterology. 2008 Aug;135(2):508-17.
Title: Constitutive CXCL12 expression induces anoikis in colorectal carcinoma cells.
Author: Wendt, Michael K|Drury, Luke J|Vongsa, Rebecca A|Dwinell, Michael B
PMID: 18558091
Journal: Oncogene. 2008 Dec 4;27(57):7192-200.
Title: Therapeutic targeting of Id2 reduces growth of human colorectal carcinoma in the murine liver.
Author: Gray, M J|Dallas, N A|Van Buren, G|Xia, L|Yang, A D|Somcio, R J|Gaur, P|Mangala, L S|Vivas-Mejia, P E|Fan, F|Sanguino, A M|Gallick, G E|Lopez-Berestein, G|Sood, A K|Ellis, L M
PMID: 18806828
Journal: Cancer. 2009 Oct 1;115(19):4459-69.
Title: Gold (III) porphyrin complexes induce apoptosis and cell cycle arrest and inhibit tumor growth in colon cancer.
Author: Tu, Shuiping|Wai-Yin Sun, Raymond|Lin, Marie C M|Tao Cui, Jian|Zou, Bing|Gu, Qing|Kung, Hsiang-Fu|Che, Chi-Ming|Wong, Benjamin C Y
PMID: 19572413
Journal: Ann Pathol. 2009 Oct;29(5):370-5.
Title: [Detection of apoptosis in vivo: comparison of different methods in histological sections of subcutaneous xenografts of HT29 human colon adenocarcinoma].
Author: Bressenot, Aude|Zimmer, Olivia|Marchal, Sophie|Gauchotte, Guillaume|Montagne, Karine|Plenat, Francois
PMID: 20004835
Journal: Zhonghua Zhong Liu Za Zhi. 2009 Jul;31(7):485-9.
Title: [Investigation of the mechanisms of coagulation factor VIIa-induced colon cancer SW620 cell proliferation and migration].
Author: Shi, Wen-Xia|Zhou, Hong|Li, Na|Huang, Hong-Liang|Zhou, Bao-Cheng
PMID: 19950693
Journal: BMC Cancer. 2009 May 21;9:158.
Title: IGF-I activates caspases 3/7, 8 and 9 but does not induce cell death in colorectal cancer cells.
Author: Yang, Shi Yu|Bolvin, Capucine|Sales, Kevin M|Fuller, Barry|Seifalian, Alexander M|Winslet, Marc C
PMID: 19460165
Journal: Gastroenterology. 2009 Sep;137(3):955-64, 964.e1-2.
Title: Ca2+-dependent K+ efflux regulates deoxycholate-induced apoptosis of BHK-21 and Caco-2 cells.
Author: Gerbino, Andrea|Ranieri, Marianna|Lupo, Stefania|Caroppo, Rosa|Debellis, Lucantonio|Maiellaro, Isabella|Caratozzolo, Mariano F|Lopez, Francesco|Colella, Matilde
PMID: 19328800
Journal: J Mol Med (Berl). 2010 Jun;88(6):609-22.
Title: Systematic genetic dissection of p14ARF-mediated mitochondrial cell death signaling reveals a key role for p21CDKN1 and the BH3-only protein Puma/bbc3.
Author: Hemmati, Philipp G|Muer, Annika|Gillissen, Bernd|Overkamp, Tim|Milojkovic, Ana|Wendt, Jana|Dorken, Bernd|Daniel, Peter T
PMID: 20419447
Journal: Br J Nutr. 2010 Sep;104(6):824-32.
Title: Apoptosis-inducing factor and caspase-dependent apoptotic pathways triggered by different grape seed extracts on human colon cancer cell line Caco-2.
Author: Dinicola, Simona|Cucina, Alessandra|Pasqualato, Alessia|Proietti, Sara|D'Anselmi, Fabrizio|Pasqua, Gabriella|Santamaria, Anna Rita|Coluccia, Pierpaolo|Lagana, Aldo|Antonacci, Donato|Giuliani, Alessandro|Bizzarri, Mariano
PMID: 20540818
Journal: Mol Med Rep. 2010 Mar-Apr;3(2):269-74.
Title: Tissue factor-factor VIIa regulates interleukin-8, tissue factor and caspase-7 expression in SW620 cells through protease-activated receptor-2 activation.
Author: Zhou, Hong|Shi, Wenxia|Zhou, Baocheng|Guo, Donglin|Wang, Ting
PMID: 21472232
Journal: J Cancer Res Clin Oncol. 2011 Apr;137(4):705-13.
Title: RIPK1 and CASP7 polymorphism as prognostic markers for survival in patients with colorectal cancer after complete resection.
Author: Chae, Yee Soo|Kim, Jong Gwang|Sohn, Sang Kyun|Lee, Su Jeong|Kang, Byung Woog|Moon, Joon Ho|Park, Jae Yong|Jeon, Seong Woo|Bae, Han-Ik|Choi, Gyu Seog|Jun, Soo-Han
PMID: 20567846
Journal: Oncol Rep. 2011 Feb;25(2):503-11.
Title: Activation of PAR2 or/and TLR4 promotes SW620 cell proliferation and migration via phosphorylation of ERK1/2.
Author: Zhou, Baocheng|Zhou, Hong|Ling, Shucai|Guo, Donglin|Yan, Yihong|Zhou, Fang|Wu, Ying
PMID: 21152870
Journal: J Cell Biochem. 2011 Feb;112(2):643-52.
Title: Phloroglucinol derivative MCPP induces cell apoptosis in human colon cancer.
Author: Huang, Ssu-Ming|Cheung, Chi-Wai|Chang, Chih-Shiang|Tang, Chih-Hsin|Liu, Ju-Fang|Lin, Yu-Hsin|Chen, Jia-Hong|Ko, Shihi-Hsun|Wong, Kar-Lok|Lu, Dah-Yuu
PMID: 21268086
Journal: Toxicol Appl Pharmacol. 2011 Aug 1;254(3):288-98.
Title: 5-Methoxyflavanone induces cell cycle arrest at the G2/M phase, apoptosis and autophagy in HCT116 human colon cancer cells.
Author: Shin, Soon Young|Hyun, Jiye|Yu, Jae-Ran|Lim, Yoongho|Lee, Young Han
PMID: 21616090
Journal: Tumour Biol. 2011 Oct;32(5):921-30.
Title: Involvement of ERK1/2/NF-kappaB signal transduction pathway in TF/FVIIa/PAR2-induced proliferation and migration of colon cancer cell SW620.
Author: Guo, Donglin|Zhou, Hong|Wu, Ying|Zhou, Fang|Xu, Guoying|Wen, Haiping|Zhang, Xianmei
PMID: 21625939
Journal: Zhonghua Zhong Liu Za Zhi. 2011 Sep;33(9):649-53.
Title: [Role of NF-kappaB in factor VIIa-induced proliferation and migration of colon cancer cell line SW620 cells].
Author: Guo, Dong-lin|Zhou, Hong|Wu, Ying|Zhou, Fang|Zhang, Xian-mei|Xu, Guo-ying|Wen, Hai-ping
PMID: 22340043
Journal: Cell Biol Int. 2012 Mar 1;36(3):289-96.
Title: PEG-liposomal oxaliplatin induces apoptosis in human colorectal cancer cells via Fas/FasL and caspase-8.
Author: Yang, Chuang|Liu, Hai-Zhong|Fu, Zhong-Xue
PMID: 21888623
Journal: Life Sci. 2012 Dec 17;91(25-26):1336-44.
Title: Phenethyl caffeate benzo[kl]xanthene lignan with DNA interacting properties induces DNA damage and apoptosis in colon cancer cells.
Author: Vijayakurup, Vinod|Carmela, Spatafora|Carmelo, Daquino|Corrado, Tringali|Srinivas, Priya|Gopala, Srinivas
PMID: 23123449
Journal: Life Sci. 2012 Dec 17;91(25-26):1295-303.
Title: Sophoridine exerts an anti-colorectal carcinoma effect through apoptosis induction in vitro and in vivo.
Author: Liang, Lei|Wang, Xiao-Yan|Zhang, Xu-Hui|Ji, Bo|Yan, Hua-Cheng|Deng, Hong-Zhu|Wu, Xin-Rong
PMID: 23069582
Journal: Can J Aging. 2012 Jun;31(2):161-71.
Title: Exercise training reduces inflammatory mediators in the intestinal tract of healthy older adult mice.
Author: Packer, Nicholas|Hoffman-Goetz, Laurie
PMID: 22647663
Journal: Pharmacology. 2012;89(1-2):91-8.
Title: Aloe emodin induces G2/M cell cycle arrest and apoptosis via activation of caspase-6 in human colon cancer cells.
Author: Suboj, Priya|Babykutty, Suboj|Srinivas, Priya|Gopala, Srinivas
PMID: 22343391
Journal: Acta Pharmacol Sin. 2012 Jan;33(1):120-6.
Title: Epigallocatechin-3-gallate inhibits proliferation and migration of human colon cancer SW620 cells in vitro.
Author: Zhou, Fang|Zhou, Hong|Wang, Ting|Mu, Yuan|Wu, Biao|Guo, Dong-lin|Zhang, Xian-mei|Wu, Ying
PMID: 22101170
Journal: Br J Pharmacol. 2012 Mar;165(6):1678-87.
Title: The orexin receptor OX(1)R in colon cancer: a promising therapeutic target and a new paradigm in G protein-coupled receptor signalling through ITIMs.
Author: Laburthe, Marc|Voisin, Thierry
PMID: 21627633
Journal: Cancer Res Treat. 2012 Mar;44(1):32-6.
Title: Prognostic Impact of Polymorphisms in the CASPASE Genes on Survival of Patients with Colorectal Cancer.
Author: Choi, Jun Young|Kim, Jong Gwang|Lee, You Jin|Chae, Yee Soo|Sohn, Sang Kyun|Moon, Joon Ho|Kang, Byung Woog|Jung, Min Kyu|Jeon, Seong Woo|Park, Jun Seok|Choi, Gyu Seog
PMID: 22500158
Journal: J Pharmacol Sci. 2013;121(1):17-24. Epub 2012 Dec 26.
Title: Tautomycetin induces apoptosis by inactivating Akt through a PP1-independent signaling pathway in human breast cancer cells.
Author: Niu, Mingshan|Sun, Yan|Liu, Xuejiao|Tang, Li|Qiu, Rongguo
PMID: 23269238
Journal: PLoS One. 2013;8(1):e53664.
Title: bis-Dehydroxy-Curcumin triggers mitochondrial-associated cell death in human colon cancer cells through ER-stress induced autophagy.
Author: Basile, Valentina|Belluti, Silvia|Ferrari, Erika|Gozzoli, Chiara|Ganassi, Sonia|Quaglino, Daniela|Saladini, Monica|Imbriano, Carol
PMID: 23326480
Journal: Mar Drugs. 2013 Jan 21;11(1):194-212.
Title: The effect of sulfated (1-->3)-alpha-l-fucan from the brown alga Saccharina cichorioides Miyabe on resveratrol-induced apoptosis in colon carcinoma Cells.
Author: Vishchuk, Olesia S|Ermakova, Svetlana P|Zvyagintseva, Tatyana N
PMID: 23337253
Journal: RNA Biol. 2013 Feb;10(2):287-300.
Title: Large-scale screening identifies a novel microRNA, miR-15a-3p, which induces apoptosis in human cancer cell lines.
Author: Druz, Aliaksandr|Chen, Yu-Chi|Guha, Rajarshi|Betenbaugh, Michael|Martin, Scott E|Shiloach, Joseph
PMID: 23353574
Journal: Phytomedicine. 2013 Apr 15;20(6):528-36.
Title: Cytotoxicity and modes of action of four naturally occuring benzophenones: 2,2',5,6'-tetrahydroxybenzophenone, guttiferone E, isogarcinol and isoxanthochymol.
Author: Kuete, Victor|Tchakam, Patricia D|Wiench, Benjamin|Ngameni, Bathelemy|Wabo, Hippolyte K|Tala, Michel F|Moungang, Marlyse L|Ngadjui, Bonaventure T|Murayama, Tetsuya|Efferth, Thomas
PMID: 23507522
Journal: Evid Based Complement Alternat Med. 2013;2013:702869.
Title: Methanolic extracts of bitter melon inhibit colon cancer stem cells by affecting energy homeostasis and autophagy.
Author: Kwatra, Deep|Subramaniam, Dharmalingam|Ramamoorthy, Prabhu|Standing, David|Moran, Elizabeth|Velayutham, Ravichandiran|Mitra, Ashim|Umar, Shahid|Anant, Shrikant
PMID: 23533514
Journal: Cell Death Dis. 2014 Jan 9;5:e983.
Title: Antioxidants decrease the apoptotic effect of 5-Fu in colon cancer by regulating Src-dependent caspase-7 phosphorylation.
Author: Fu, Y|Yang, G|Zhu, F|Peng, C|Li, W|Li, H|Kim, H-G|Bode, A M|Dong, Z|Dong, Z
PMID: 24407236
Journal: Int J Mol Sci. 2014 Feb 17;15(2):2722-37.
Title: Mechanisms underlying apoptosis-inducing effects of Kaempferol in HT-29 human colon cancer cells.
Author: Lee, Hyun Sook|Cho, Han Jin|Yu, Rina|Lee, Ki Won|Chun, Hyang Sook|Park, Jung Han Yoon
PMID: 24549175
Journal: Mol Cancer. 2014 May 26;13:124.
Title: microRNA-139-5p exerts tumor suppressor function by targeting NOTCH1 in colorectal cancer.
Author: Zhang, Lijing|Dong, Yujuan|Zhu, Nana|Tsoi, Ho|Zhao, Zengren|Wu, Chung Wah|Wang, Kunning|Zheng, Shu|Ng, Simon Sm|Chan, Francis Kl|Sung, Joseph Jy|Yu, Jun
PMID: 24885920
Journal: J Med Food. 2015 Mar;18(3):332-6.
Title: Khz (fusion product of Ganoderma lucidum and Polyporus umbellatus mycelia) induces apoptosis in human colon carcinoma HCT116 cells, accompanied by an increase in reactive oxygen species, activation of caspase 3, and increased intracellular Ca(2)(+).
Author: Kim, Tae Hwan|Kim, Ju Sung|Kim, Zoo Haye|Huang, Ren Bin|Chae, Young Lye|Wang, Ren Sheng
PMID: 25489715
Journal: Int J Cancer Res (Tortola). 2015 Mar;49(1):1655-1662.
Title: Ambiguine I Isonitrile from Fischerella ambigua Induces Caspase-Independent Cell Death in MCF-7 Hormone Dependent Breast Cancer Cells.
Author: Acuna, Ulyana Munoz|Zi, Jiachen|Orjala, Jimmy|Carcache de Blanco, Esperanza J
PMID: 26753095
Journal: Acta Pharmacol Sin. 2015 Sep;36(9):1074-84.
Title: New benzimidazole acridine derivative induces human colon cancer cell apoptosis in vitro via the ROS-JNK signaling pathway.
Author: Chen, Kang|Chu, Bi-zhu|Liu, Feng|Li, Bin|Gao, Chun-mei|Li, Lu-lu|Sun, Qin-sheng|Shen, Zhi-fa|Jiang, Yu-yang
PMID: 26235743
Journal: Radiat Oncol. 2015 Jul 22;10:149.
Title: Role of membrane Hsp70 in radiation sensitivity of tumor cells.
Author: Murakami, Naoya|Kuhnel, Annett|Schmid, Thomas E|Ilicic, Katarina|Stangl, Stefan|Braun, Isabella S|Gehrmann, Mathias|Molls, Michael|Itami, Jun|Multhoff, Gabriele
PMID: 26197988
Journal: J Ethnopharmacol. 2015 Jun 20;168:291-304.
Title: Elephantopus scaber induces apoptosis through ROS-dependent mitochondrial signaling pathway in HCT116 human colorectal carcinoma cells.
Author: Chan, Chim Kei|Supriady, Hadi|Goh, Bey Hing|Kadir, Habsah Abdul
PMID: 25861953
Journal: Arch Toxicol. 2015 Oct;89(10):1829-46.
Title: Lipoic acid induces p53-independent cell death in colorectal cancer cells and potentiates the cytotoxicity of 5-fluorouracil.
Author: Dorsam, Bastian|Goder, Anja|Seiwert, Nina|Kaina, Bernd|Fahrer, Jorg
PMID: 25526924
Journal: Asian Pac J Cancer Prev. 2016;17(4):1947-59.
Title: Harmal Extract Induces Apoptosis of HCT116 Human Colon Cancer Cells, Mediated by Inhibition of Nuclear Factor-kappaB and Activator Protein-1 Signaling Pathways and Induction of Cytoprotective Genes.
Author: Elkady, Ayman I|Hussein, Rania A|El-Assouli, Sufian M
PMID: 27221880
Journal: Oncol Rep. 2016 Oct;36(4):1875-85.
Title: Combination of the histone deacetylase inhibitor depsipeptide and 5-fluorouracil upregulates major histocompatibility complex class II and p21 genes and activates caspase-3/7 in human colon cancer HCT-116 cells.
Author: Okada, Kouji|Hakata, Shuko|Terashima, Jun|Gamou, Toshie|Habano, Wataru|Ozawa, Shogo
PMID: 27509880
Journal: Biochem Biophys Res Commun. 2016 Oct 28;479(4):913-919.
Title: p53-dependent and -independent mechanisms are involved in (E)-1-(2-hydroxyphenyl)-3-(2-methoxynaphthalen-1-yl)prop-2-en-1-one (HMP)-induced apoptosis in HCT116 colon cancer cells.
Author: Shin, Soon Young|Ahn, Seunghyun|Koh, Dongsoo|Lim, Yoongho
PMID: 27641669
Journal: Int J Oncol. 2017 Jan;50(1):283-289.
Title: 2'-Hydroxycinnamaldehyde induces apoptosis through HSF1-mediated BAG3 expression.
Author: Nguyen, Hai-Anh|Kim, Soo-A
PMID: 27922674
Journal: Cell Physiol Biochem. 2018;45(2):808-818.
Title: Serine/Threonine Kinase 35, a Target Gene of STAT3, Regulates the Proliferation and Apoptosis of Osteosarcoma Cells.
Author: Wu, Zhong|Liu, Jie|Hu, Siyuan|Zhu, Yuchang|Li, Shaohua
PMID: 29414823
Journal: PLoS One. 2018 May 17;13(5):e0197563.
Title: Antitumor, antioxidant and anti-inflammatory activities of kaempferol and its corresponding glycosides and the enzymatic preparation of kaempferol.
Author: Wang, Jingqiu|Fang, Xianying|Ge, Lin|Cao, Fuliang|Zhao, Linguo|Wang, Zhenzhong|Xiao, Wei
PMID: 29771951
Journal: Onco Targets Ther. 2018 Jun 5;11:3313-3322.
Title: Novel quinazoline-based sulfonamide derivative (3D) induces apoptosis in colorectal cancer by inhibiting JAK2-STAT3 pathway.
Author: Al-Obeed, Omar|Vaali-Mohammed, Mansoor-Ali|Eldehna, Wagdy M|Al-Khayal, Khayal|Mahmood, Amer|Abdel-Aziz, Hatem A|Zubaidi, Ahmed|Alafeefy, Ahmed|Abdulla, Maha|Ahmad, Rehan
PMID: 29892198
Journal: Oncol Lett. 2018 Nov;16(5):6140-6146.
Title: CHSY1 promoted proliferation and suppressed apoptosis in colorectal cancer through regulation of the NFkappaB and/or caspase-3/7 signaling pathway.
Author: Zeng, Lifeng|Qian, Jinrong|Luo, Xiaojiang|Zhou, Aiqun|Zhang, Zhiyong|Fang, Quangang
PMID: 30344756