Primary Site >> Colorectal Cancer
Gene >> CASP7
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Ref: Characterization of bile salt-induced apoptosis in colon cancer cell lines. PMID: 10945641 |
Ref: Caspase 7 downregulation as an immunohistochemical marker of colonic carcinoma. PMID: 11381362 |
Ref: Dephosphorylation of p53 during cell death by N-alpha-tosyl-L-phenylalanyl chloromethyl ketone. PMID: 12821135 Ref: Regulation of caspase expression and apoptosis by adenomatous polyposis coli. PMID: 12907606 Ref: Inactivating mutations of CASPASE-7 gene in human cancers. PMID: 12970753 |
Ref: Deleted in oral cancer-1 expression upregulates proapoptosis elements in microsatellite-unstable human colorectal cancer. PMID: 14761923 Ref: Requirement of histone deacetylase activity for signaling by STAT1. PMID: 15123634 Ref: Oncogenic Ras promotes butyrate-induced apoptosis through inhibition of gelsolin expression. PMID: 15213223 Ref: Orexins acting at native OX(1) receptor in colon cancer and neuroblastoma cells or at recombinant OX(1) receptor suppress cell growth by inducing apoptosis. PMID: 15310763 |
Ref: Bak functionally complements for loss of Bax during p14ARF-induced mitochondrial apoptosis in human cancer cells. PMID: 16847458 |
Ref: Aspirin blocks proliferation in colon cells by inducing a G1 arrest and apoptosis through activation of the checkpoint kinase ATM. PMID: 17510082 |
Ref: CUGBP2 downregulation by prostaglandin E2 protects colon cancer cells from radiation-induced mitotic catastrophe. PMID: 18325984 Ref: Constitutive CXCL12 expression induces anoikis in colorectal carcinoma cells. PMID: 18558091 Ref: Therapeutic targeting of Id2 reduces growth of human colorectal carcinoma in the murine liver. PMID: 18806828 |
Ref: Ca2+-dependent K+ efflux regulates deoxycholate-induced apoptosis of BHK-21 and Caco-2 cells. PMID: 19328800 Ref: IGF-I activates caspases 3/7, 8 and 9 but does not induce cell death in colorectal cancer cells. PMID: 19460165 Ref: Gold (III) porphyrin complexes induce apoptosis and cell cycle arrest and inhibit tumor growth in colon cancer. PMID: 19572413 Ref: [Investigation of the mechanisms of coagulation factor VIIa-induced colon cancer SW620 cell proliferation and migration]. PMID: 19950693 Ref: [Detection of apoptosis in vivo: comparison of different methods in histological sections of subcutaneous xenografts of HT29 human colon adenocarcinoma]. PMID: 20004835 |
Ref: Systematic genetic dissection of p14ARF-mediated mitochondrial cell death signaling reveals a key role for p21CDKN1 and the BH3-only protein Puma/bbc3. PMID: 20419447 Ref: Apoptosis-inducing factor and caspase-dependent apoptotic pathways triggered by different grape seed extracts on human colon cancer cell line Caco-2. PMID: 20540818 Ref: Tissue factor-factor VIIa regulates interleukin-8, tissue factor and caspase-7 expression in SW620 cells through protease-activated receptor-2 activation. PMID: 21472232 |
Ref: RIPK1 and CASP7 polymorphism as prognostic markers for survival in patients with colorectal cancer after complete resection. PMID: 20567846 Ref: Activation of PAR2 or/and TLR4 promotes SW620 cell proliferation and migration via phosphorylation of ERK1/2. PMID: 21152870 Ref: Phloroglucinol derivative MCPP induces cell apoptosis in human colon cancer. PMID: 21268086 Ref: 5-Methoxyflavanone induces cell cycle arrest at the G2/M phase, apoptosis and autophagy in HCT116 human colon cancer cells. PMID: 21616090 Ref: Involvement of ERK1/2/NF-kappaB signal transduction pathway in TF/FVIIa/PAR2-induced proliferation and migration of colon cancer cell SW620. PMID: 21625939 Ref: [Role of NF-kappaB in factor VIIa-induced proliferation and migration of colon cancer cell line SW620 cells]. PMID: 22340043 |
Ref: The orexin receptor OX(1)R in colon cancer: a promising therapeutic target and a new paradigm in G protein-coupled receptor signalling through ITIMs. PMID: 21627633 Ref: PEG-liposomal oxaliplatin induces apoptosis in human colorectal cancer cells via Fas/FasL and caspase-8. PMID: 21888623 Ref: Epigallocatechin-3-gallate inhibits proliferation and migration of human colon cancer SW620 cells in vitro. PMID: 22101170 Ref: Aloe emodin induces G2/M cell cycle arrest and apoptosis via activation of caspase-6 in human colon cancer cells. PMID: 22343391 Ref: Prognostic Impact of Polymorphisms in the CASPASE Genes on Survival of Patients with Colorectal Cancer. PMID: 22500158 Ref: Exercise training reduces inflammatory mediators in the intestinal tract of healthy older adult mice. PMID: 22647663 Ref: Sophoridine exerts an anti-colorectal carcinoma effect through apoptosis induction in vitro and in vivo. PMID: 23069582 Ref: Phenethyl caffeate benzo[kl]xanthene lignan with DNA interacting properties induces DNA damage and apoptosis in colon cancer cells. PMID: 23123449 |
Ref: Tautomycetin induces apoptosis by inactivating Akt through a PP1-independent signaling pathway in human breast cancer cells. PMID: 23269238 Ref: bis-Dehydroxy-Curcumin triggers mitochondrial-associated cell death in human colon cancer cells through ER-stress induced autophagy. PMID: 23326480 Ref: The effect of sulfated (1-->3)-alpha-l-fucan from the brown alga Saccharina cichorioides Miyabe on resveratrol-induced apoptosis in colon carcinoma Cells. PMID: 23337253 Ref: Large-scale screening identifies a novel microRNA, miR-15a-3p, which induces apoptosis in human cancer cell lines. PMID: 23353574 Ref: Cytotoxicity and modes of action of four naturally occuring benzophenones: 2,2',5,6'-tetrahydroxybenzophenone, guttiferone E, isogarcinol and isoxanthochymol. PMID: 23507522 Ref: Methanolic extracts of bitter melon inhibit colon cancer stem cells by affecting energy homeostasis and autophagy. PMID: 23533514 |
Ref: Antioxidants decrease the apoptotic effect of 5-Fu in colon cancer by regulating Src-dependent caspase-7 phosphorylation. PMID: 24407236 Ref: Mechanisms underlying apoptosis-inducing effects of Kaempferol in HT-29 human colon cancer cells. PMID: 24549175 Ref: microRNA-139-5p exerts tumor suppressor function by targeting NOTCH1 in colorectal cancer. PMID: 24885920 |
Ref: Khz (fusion product of Ganoderma lucidum and Polyporus umbellatus mycelia) induces apoptosis in human colon carcinoma HCT116 cells, accompanied by an increase in reactive oxygen species, activation of caspase 3, and increased intracellular Ca(2)(+). PMID: 25489715 Ref: Lipoic acid induces p53-independent cell death in colorectal cancer cells and potentiates the cytotoxicity of 5-fluorouracil. PMID: 25526924 Ref: Elephantopus scaber induces apoptosis through ROS-dependent mitochondrial signaling pathway in HCT116 human colorectal carcinoma cells. PMID: 25861953 Ref: Role of membrane Hsp70 in radiation sensitivity of tumor cells. PMID: 26197988 Ref: New benzimidazole acridine derivative induces human colon cancer cell apoptosis in vitro via the ROS-JNK signaling pathway. PMID: 26235743 Ref: Ambiguine I Isonitrile from Fischerella ambigua Induces Caspase-Independent Cell Death in MCF-7 Hormone Dependent Breast Cancer Cells. PMID: 26753095 |
Ref: Harmal Extract Induces Apoptosis of HCT116 Human Colon Cancer Cells, Mediated by Inhibition of Nuclear Factor-kappaB and Activator Protein-1 Signaling Pathways and Induction of Cytoprotective Genes. PMID: 27221880 Ref: Combination of the histone deacetylase inhibitor depsipeptide and 5-fluorouracil upregulates major histocompatibility complex class II and p21 genes and activates caspase-3/7 in human colon cancer HCT-116 cells. PMID: 27509880 Ref: p53-dependent and -independent mechanisms are involved in (E)-1-(2-hydroxyphenyl)-3-(2-methoxynaphthalen-1-yl)prop-2-en-1-one (HMP)-induced apoptosis in HCT116 colon cancer cells. PMID: 27641669 |
Ref: 2'-Hydroxycinnamaldehyde induces apoptosis through HSF1-mediated BAG3 expression. PMID: 27922674 |
Ref: Serine/Threonine Kinase 35, a Target Gene of STAT3, Regulates the Proliferation and Apoptosis of Osteosarcoma Cells. PMID: 29414823 Ref: Antitumor, antioxidant and anti-inflammatory activities of kaempferol and its corresponding glycosides and the enzymatic preparation of kaempferol. PMID: 29771951 Ref: Novel quinazoline-based sulfonamide derivative (3D) induces apoptosis in colorectal cancer by inhibiting JAK2-STAT3 pathway. PMID: 29892198 Ref: CHSY1 promoted proliferation and suppressed apoptosis in colorectal cancer through regulation of the NFkappaB and/or caspase-3/7 signaling pathway. PMID: 30344756 |