Literatures

Primary Site >> Colorectal Cancer

Gene >> CA9

1.
Journal:	Am J Pathol. 1998 Jul;153(1):279-85.
Title:	Immunohistochemical study of colorectal tumors for expression of a novel transmembrane carbonic anhydrase, MN/CA IX, with potential value as a marker of cell proliferation.
Author:	Saarnio, J\|Parkkila, S\|Parkkila, A K\|Haukipuro, K\|Pastorekova, S\|Pastorek, J\|Kairaluoma, M I\|Karttunen, T J
PMID:	9665489

2.
Journal:	Dig Dis Sci. 2001 Oct;46(10):2179-86.
Title:	Differential expression of cytoplasmic carbonic anhydrases, CA I and II, and membrane-associated isozymes, CA IX and XII, in normal mucosa of large intestine and in colorectal tumors.
Author:	Kivela, A J\|Saarnio, J\|Karttunen, T J\|Kivela, J\|Parkkila, A K\|Pastorekova, S\|Pastorek, J\|Waheed, A\|Sly, W S\|Parkkila, T S\|Rajaniemi, H
PMID:	11680594

3.
Journal:	Int J Cancer. 2003 Jul 20;105(6):873-81.
Title:	Biodistribution and pharmacokinetics of 125I-labeled monoclonal antibody M75 specific for carbonic anhydrase IX, an intrinsic marker of hypoxia, in nude mice xenografted with human colorectal carcinoma.
Author:	Chrastina, Adrian\|Zavada, Jan\|Parkkila, Seppo\|Kaluz, Stefan\|Kaluzova, Milota\|Rajcani, Julius\|Pastorek, Jaromir\|Pastorekova, Silvia
PMID:	12767076

4.
Journal:	Br J Cancer. 2004 Apr 5;90(7):1429-36.
Title:	Breast adenocarcinoma liver metastases, in contrast to colorectal cancer liver metastases, display a non-angiogenic growth pattern that preserves the stroma and lacks hypoxia.
Author:	Stessels, F\|Van den Eynden, G\|Van der Auwera, I\|Salgado, R\|Van den Heuvel, E\|Harris, A L\|Jackson, D G\|Colpaert, C G\|van Marck, E A\|Dirix, L Y\|Vermeulen, P B
PMID:	15054467

5.
Journal:
Title:	(177)Lu-Benzyl-diethylenetriamine pentaacetic acid-anti-carbonic anhydrase IX small immunoprotein A3
Author:	Leung, Kam
PMID:	20641383

6.
Journal:
Title:	(89)Zr-N-Succinyldesferal-chimeric monoclonal antibody G250
Author:	Leung, Kam
PMID:	20641994

7.
Journal:
Title:	(124)I-Chimeric monoclonal antibody G250
Author:	Leung, Kam
PMID:	20641997

8.
Journal:
Title:	(125)I-Labeled mouse anti-human carbonic anhydrase IX monoclonal antibody
Author:	Shan, Liang
PMID:	22675743

9.
Journal:	Cancer Lett. 2005 Jan 10;217(1):43-52.
Title:	Norcantharidin-induced apoptosis in oral cancer cells is associated with an increase of proapoptotic to antiapoptotic protein ratio.
Author:	Kok, Sang-Heng\|Cheng, Shih-Jung\|Hong, Chi-Yuan\|Lee, Jang-Jaer\|Lin, Sze-Kwan\|Kuo, Ying-Shiung\|Chiang, Chun-Pin\|Kuo, Mark Yen-Ping
PMID:	15596295

10.
Journal:	World J Gastroenterol. 2005 May 7;11(17):2616-25.
Title:	Expression of von Hippel-Lindau tumor suppressor and tumor-associated carbonic anhydrases IX and XII in normal and neoplastic colorectal mucosa.
Author:	Kivela, Antti-J\|Parkkila, Seppo\|Saarnio, Juha\|Karttunen, Tuomo-J\|Kivela, Jyrki\|Parkkila, Anna-Kaisa\|Bartosova, Maria\|Mucha, Vojtech\|Novak, Michal\|Waheed, Abdul\|Sly, William-S\|Rajaniemi, Hannu\|Pastorekova, Silvia\|Pastorek, Jaromir
PMID:	15849821

11.
Journal:	Clin Cancer Res. 2005 Aug 1;11(15):5526-33.
Title:	A phase II trial with pharmacodynamic endpoints of the proteasome inhibitor bortezomib in patients with metastatic colorectal cancer.
Author:	Mackay, Helen\|Hedley, David\|Major, Pierre\|Townsley, Carol\|Mackenzie, Mary\|Vincent, Mark\|Degendorfer, Pam\|Tsao, Ming-Sound\|Nicklee, Trudey\|Birle, Diana\|Wright, John\|Siu, Lillian\|Moore, Malcolm\|Oza, Amit
PMID:	16061869

12.
Journal:	Cancer Res. 2005 Aug 15;65(16):7259-66.
Title:	Reduced expression of hypoxia-inducible factor-1alpha in perinecrotic regions of solid tumors.
Author:	Sobhanifar, Solmaz\|Aquino-Parsons, Christina\|Stanbridge, Eric J\|Olive, Peggy
PMID:	16103077

13.
Journal:	Int J Radiat Oncol Biol Phys. 2006 Feb 1;64(2):473-82. Epub 2005 Oct 19.
Title:	Hypoxia in relation to vasculature and proliferation in liver metastases in patients with colorectal cancer.
Author:	van Laarhoven, Hanneke W M\|Kaanders, Johannes H A M\|Lok, Jasper\|Peeters, Wenny J M\|Rijken, Paul F J W\|Wiering, Bastiaan\|Ruers, Theo J M\|Punt, Cornelis J A\|Heerschap, Arend\|van der Kogel, Albert J
PMID:	16242253

14.
Journal:	Br J Cancer. 2006 Sep 18;95(6):735-43.
Title:	EMAP-II-dependent lymphocyte killing is associated with hypoxia in colorectal cancer.
Author:	Youssef, M M S\|Symonds, P\|Ellis, I O\|Murray, J C
PMID:	16929248

15.
Journal:	Int J Radiat Oncol Biol Phys. 2006 May 1;65(1):246-54.
Title:	Hypoxia in human colorectal adenocarcinoma: comparison between extrinsic and potential intrinsic hypoxia markers.
Author:	Goethals, Laurence\|Debucquoy, Annelies\|Perneel, Christiaan\|Geboes, Karel\|Ectors, Nadine\|De Schutter, Harlinde\|Penninckx, Freddy\|McBride, William H\|Begg, Adrian C\|Haustermans, Karin M
PMID:	16618579

16.
Journal:	J Pathol. 2006 Apr;208(5):607-14.
Title:	A new approach to the validation of tissue microarrays.
Author:	Goethals, L\|Perneel, C\|Debucquoy, A\|De Schutter, H\|Borghys, D\|Ectors, N\|Geboes, K\|McBride, W H\|Haustermans, K M
PMID:	16435284

17.
Journal:	Cancer Biol Ther. 2007 Jan;6(1):70-5.
Title:	Detecting changes in tumor hypoxia with carbonic anhydrase IX and pimonidazole.
Author:	Shin, Kyung Hwan\|Diaz-Gonzalez, Juan A\|Russell, James\|Chen, Qing\|Burgman, Paul\|Li, Xiao-Feng\|Ling, C Clifton
PMID:	17172824

18.
Journal:	Cancer Res. 2007 Feb 15;67(4):1735-43.
Title:	Suppression of the hypoxia-inducible factor-1 response in cervical carcinoma xenografts by proteasome inhibitors.
Author:	Birle, Diana C\|Hedley, David W
PMID:	17308115

19.
Journal:	Cell Oncol. 2007;29(3):229-40.
Title:	Stromal expression of hypoxia regulated proteins is an adverse prognostic factor in colorectal carcinomas.
Author:	Cleven, Arjen H G\|van Engeland, Manon\|Wouters, Bradly G\|de Bruine, Adriaan P
PMID:	17452775

20.
Journal:	Biomarkers. 2007 Mar-Apr;12(2):214-20.
Title:	MN/CA9: a potential gene marker for detection of malignant cells in effusions.
Author:	Li, G\|Passebosc-Faure, K\|Feng, G\|Lambert, C\|Cottier, M\|Gentil-Perret, A\|Fournel, P\|Perol, M\|Genin, C
PMID:	17536770

21.
Journal:	Int J Cancer. 2007 Dec 1;121(11):2443-50.
Title:	Hypoxia upregulates carcinoembryonic antigen expression in cancer cells.
Author:	Kokkonen, Nina\|Ulibarri, Ines Fernandez\|Kauppila, Annika\|Luosujarvi, Hanne\|Rivinoja, Antti\|Pospiech, Helmut\|Kellokumpu, Ilmo\|Kellokumpu, Sakari
PMID:	17657737

22.
Journal:	Cancer Epidemiol Biomarkers Prev. 2007 Sep;16(9):1760-6.
Title:	Carbonic anhydrase IX is highly expressed in hereditary nonpolyposis colorectal cancer.
Author:	Niemela, Anssi M\|Hynninen, Piritta\|Mecklin, Jukka-Pekka\|Kuopio, Teijo\|Kokko, Antti\|Aaltonen, Lauri\|Parkkila, Anna-Kaisa\|Pastorekova, Silvia\|Pastorek, Jaromir\|Waheed, Abdul\|Sly, William S\|Orntoft, Torben F\|Kruhoffer, Mogens\|Haapasalo, Hannu\|Parkkila, Seppo
PMID:	17855694

23.
Journal:	Br J Cancer. 2008 Sep 2;99(5):727-33.
Title:	Poorer outcome in stromal HIF-2 alpha- and CA9-positive colorectal adenocarcinomas is associated with wild-type TP53 but not with BNIP3 promoter hypermethylation or apoptosis.
Author:	Cleven, A H G\|Wouters, B G\|Schutte, B\|Spiertz, A J G\|van Engeland, M\|de Bruine, A P
PMID:	18728663

24.
Journal:	Cancer Res. 2008 Oct 15;68(20):8597-606.
Title:	Noninvasive molecular imaging of hypoxia in human xenografts: comparing hypoxia-induced gene expression with endogenous and exogenous hypoxia markers.
Author:	He, Fuqiu\|Deng, Xuelong\|Wen, Bixiu\|Liu, Yueping\|Sun, Xiaorong\|Xing, Ligang\|Minami, Akiko\|Huang, Yunhong\|Chen, Qing\|Zanzonico, Pat B\|Ling, C Clifton\|Li, Gloria C
PMID:	18922936

25.
Journal:	Int J Oncol. 2008 Sep;33(3):461-8.
Title:	LC3, an autophagosome marker, is highly expressed in gastrointestinal cancers.
Author:	Yoshioka, Akiko\|Miyata, Hiroshi\|Doki, Yuichiro\|Yamasaki, Makoto\|Sohma, Itsuro\|Gotoh, Kunihito\|Takiguchi, Shuji\|Fujiwara, Yoshiyuki\|Uchiyama, Yasuo\|Monden, Morito
PMID:	18695874

26.
Journal:	Hum Pathol. 2008 Oct;39(10):1483-94.
Title:	Up-regulation of the hypoxia-inducible factor-1 transcriptional pathway in colorectal carcinomas.
Author:	Furlan, Daniela\|Sahnane, Nora\|Carnevali, Ileana\|Cerutti, Roberta\|Bertoni, Francesco\|Kwee, Ivo\|Uccella, Silvia\|Bertolini, Valentina\|Chiaravalli, Anna Maria\|Capella, Carlo
PMID:	18619649

27.
Journal:	Virchows Arch. 2008 May;452(5):535-44.
Title:	Presence of HIF-1 and related genes in normal mucosa, adenomas and carcinomas of the colorectum.
Author:	Greijer, Astrid E\|Delis-van Diemen, Pien M\|Fijneman, Remond J A\|Giles, Rachel H\|Voest, Emile E\|van Hinsbergh, Victor W M\|Meijer, Gerrit A
PMID:	18351386

28.
Journal:	Br J Cancer. 2009 Nov 17;101(10):1749-57.
Title:	Expression of delta-like ligand 4 (Dll4) and markers of hypoxia in colon cancer.
Author:	Jubb, A M\|Turley, H\|Moeller, H C\|Steers, G\|Han, C\|Li, J-L\|Leek, R\|Tan, E Y\|Singh, B\|Mortensen, N J\|Noguera-Troise, I\|Pezzella, F\|Gatter, K C\|Thurston, G\|Fox, S B\|Harris, A L
PMID:	19844231

29.
Journal:	Br J Cancer. 2009 Jul 21;101(2):372; author reply 373.
Title:	Expression of carbonic anhydrase IX suggests poor response to therapy in rectal cancer.
Author:	Span, P N\|Nagtegaal, I D\|Bussink, J
PMID:	19568246

30.
Journal:	J Biol Chem. 2009 Jul 24;284(30):20299-310.
Title:	The role of carbonic anhydrase 9 in regulating extracellular and intracellular ph in three-dimensional tumor cell growths.
Author:	Swietach, Pawel\|Patiar, Shalini\|Supuran, Claudiu T\|Harris, Adrian L\|Vaughan-Jones, Richard D
PMID:	19458084

31.
Journal:	Int J Radiat Oncol Biol Phys. 2009 Mar 15;73(4):1177-86.
Title:	Immunohistochemical detection of changes in tumor hypoxia.
Author:	Russell, James\|Carlin, Sean\|Burke, Sean A\|Wen, Bixiu\|Yang, Kwang Mo\|Ling, C Clifton
PMID:	19251089

32.
Journal:	Br J Cancer. 2009 Mar 24;100(6):874-80.
Title:	Expression of carbonic anhydrase IX suggests poor outcome in rectal cancer.
Author:	Korkeila, E\|Talvinen, K\|Jaakkola, P M\|Minn, H\|Syrjanen, K\|Sundstrom, J\|Pyrhonen, S
PMID:	19240720

33.
Journal:	Int J Colorectal Dis. 2009 Feb;24(2):129-38.
Title:	Molecular and clinico-pathological markers in rectal cancer: a tissue micro-array study.
Author:	Debucquoy, Annelies\|Goethals, Laurence\|Libbrecht, Louis\|Perneel, Christiaan\|Geboes, Karel\|Ectors, Nadine\|McBride, William H\|Haustermans, Karin
PMID:	19050903

34.
Journal:	J Cell Mol Med. 2009 Sep;13(9B):3876-87.
Title:	Cyclooxygenase-2/carbonic anhydrase-IX up-regulation promotes invasive potential and hypoxia survival in colorectal cancer cells.
Author:	Sansone, Pasquale\|Piazzi, Giulia\|Paterini, Paola\|Strillacci, Antonio\|Ceccarelli, Claudio\|Minni, Francesco\|Biasco, Guido\|Chieco, Pasquale\|Bonafe, Massimiliano
PMID:	19017360

35.
Journal:	Pathol Res Pract. 2009;205(1):1-9.
Title:	Assessment of microvessel density and carbonic anhydrase-9 (CA-9) expression in rectal cancer.
Author:	Rasheed, S\|Harris, A L\|Tekkis, P P\|Turley, H\|Silver, A\|McDonald, P J\|Talbot, I C\|Glynne-Jones, R\|Northover, J M A\|Guenther, T
PMID:	19008051

36.
Journal:	J Enzyme Inhib Med Chem. 2009 Apr;24(2):499-505.
Title:	Carbonic anhydrase inhibitors. Biphenylsulfonamides with inhibitory action towards the transmembrane, tumor-associated isozymes IX possess cytotoxic activity against human colon, lung and breast cancer cell lines.
Author:	Morsy, Salwa M I\|Badawi, Abdelfattah M\|Cecchi, Alessandro\|Scozzafava, Andrea\|Supuran, Claudiu T
PMID:	18608752

37.
Journal:	Eur J Nucl Med Mol Imaging. 2010 Feb;37(2):339-48.
Title:	Detection of hypoxia in microscopic tumors using 131I-labeled iodo-azomycin galactopyranoside (131I-IAZGP) digital autoradiography.
Author:	Li, Xiao-Feng\|Sun, Xiaorong\|Ma, Yuanyuan\|Suehiro, Makiko\|Zhang, Mutian\|Russell, James\|Humm, John L\|Ling, C Clifton\|O'Donoghue, Joseph A
PMID:	19921184

38.
Journal:	Prostate Cancer Prostatic Dis. 2010 Jun;13(2):178-81.
Title:	Carbonic anhydrase IX expression in prostate cancer.
Author:	Smyth, L G\|O'Hurley, G\|O'Grady, A\|Fitzpatrick, J M\|Kay, E\|Watson, R W G
PMID:	20038959

39.
Journal:	PLoS One. 2010 May 27;5(5):e10857.
Title:	Molecular targeting of carbonic anhydrase IX in mice with hypoxic HT29 colorectal tumor xenografts.
Author:	Carlin, Sean\|Khan, Nahida\|Ku, Thomas\|Longo, Valerie A\|Larson, Steve M\|Smith-Jones, Peter M
PMID:	20523727

40.
Journal:	Curr Pharm Des. 2010;16(29):3255-63.
Title:	Carbonic anhydrase IX as an anticancer therapy target: preclinical evaluation of internalizing monoclonal antibody directed to catalytic domain.
Author:	Zatovicova, M\|Jelenska, L\|Hulikova, A\|Csaderova, L\|Ditte, Z\|Ditte, P\|Goliasova, T\|Pastorek, J\|Pastorekova, S
PMID:	20819068

41.
Journal:	PLoS One. 2010 Dec 31;5(12):e15962.
Title:	A new peptide ligand for targeting human carbonic anhydrase IX, identified through the phage display technology.
Author:	Askoxylakis, Vasileios\|Garcia-Boy, Regine\|Rana, Shoaib\|Kramer, Susanne\|Hebling, Ulrike\|Mier, Walter\|Altmann, Annette\|Markert, Annette\|Debus, Jurgen\|Haberkorn, Uwe
PMID:	21209841

42.
Journal:	Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4382-7.
Title:	Hypoxia and lineage specification of cell line-derived colorectal cancer stem cells.
Author:	Yeung, Trevor M\|Gandhi, Shaan C\|Bodmer, Walter F
PMID:	21368208

43.
Journal:	Target Oncol. 2011 Sep;6(3):155-62.
Title:	LDH-A influences hypoxia-inducible factor 1alpha (HIF1 alpha) and is critical for growth of HT29 colon carcinoma cells in vivo.
Author:	Langhammer, Stefan\|Najjar, Maher\|Hess-Stumpp, Holger\|Thierauch, Karl-Heinz
PMID:	21660559

44.
Journal:	Anticancer Res. 2011 Dec;31(12):4529-35.
Title:	Carbonic anhydrase IX, hypoxia-inducible factor-1alpha, ezrin and glucose transporter-1 as predictors of disease outcome in rectal cancer: multivariate Cox survival models following data reduction by principal component analysis of the clinicopathological
Author:	Korkeila, Eija A\|Sundstrom, Jari\|Pyrhonen, Seppo\|Syrjanen, Kari
PMID:	22199327

45.
Journal:	Dis Colon Rectum. 2012 Sep;55(9):990-5.
Title:	Hypoxia-related proteins in patients with rectal cancer undergoing neoadjuvant combined modality therapy.
Author:	Lee-Kong, Steven A\|Ruby, Jeannine A\|Chessin, David B\|Pucciarelli, Salvatore\|Shia, Jinru\|Riedel, Elyn R\|Nitti, Donato\|Guillem, Jose G
PMID:	22874607

46.
Journal:	Biosci Rep. 2012 Dec;32(6):587-95.
Title:	Bafilomycin A1 activates HIF-dependent signalling in human colon cancer cells via mitochondrial uncoupling.
Author:	Zhdanov, Alexander V\|Dmitriev, Ruslan I\|Papkovsky, Dmitri B
PMID:	22943412

47.
Journal:	BMC Cancer. 2012 Nov 13;12:515.
Title:	Clinical procedure for colon carcinoma tissue sampling directly affects the cancer marker-capacity of VEGF family members.
Author:	Pringels, Sarah\|Van Damme, Nancy\|De Craene, Bram\|Pattyn, Piet\|Ceelen, Wim\|Peeters, Marc\|Grooten, Johan
PMID:	23148666

48.
Journal:	Int J Mol Sci. 2012 Oct 11;13(10):13030-48.
Title:	Binding of the phage display derived peptide CaIX-P1 on human colorectal carcinoma cells correlates with the expression of carbonic anhydrase IX.
Author:	Askoxylakis, Vasileios\|Ehemann, Volker\|Rana, Shoaib\|Kramer, Susanne\|Rahbari, Nuh N\|Debus, Jurgen\|Haberkorn, Uwe
PMID:	23202936

49.
Journal:	Front Oncol. 2013 Jan 7;2:199.
Title:	Knock-down of hypoxia-induced carbonic anhydrases IX and XII radiosensitizes tumor cells by increasing intracellular acidosis.
Author:	Doyen, Jerome\|Parks, Scott K\|Marcie, Serge\|Pouyssegur, Jacques\|Chiche, Johanna
PMID:	23316475

50.
Journal:	Transl Oncol. 2012 Apr;5(2):105-12. Epub 2012 Apr 1.
Title:	hERG1 Channels and Glut-1 as Independent Prognostic Indicators of Worse Outcome in Stage I and II Colorectal Cancer: A Pilot Study.
Author:	Lastraioli, Elena\|Bencini, Lapo\|Bianchini, Elisa\|Romoli, Maria Raffaella\|Crociani, Olivia\|Giommoni, Elisa\|Messerini, Luca\|Gasperoni, Silvia\|Moretti, Renato\|Di Costanzo, Francesco\|Boni, Luca\|Arcangeli, Annarosa
PMID:	22496927

51.
Journal:	Anticancer Res. 2012 Aug;32(8):3299-303.
Title:	Main effects and interactions of carbonic anhydrase IX, hypoxia-inducible factor-1alpha, ezrin and glucose transporter-1 in multivariate analysis for disease outcome in rectal cancer.
Author:	Korkeila, Eija\|Sundstrom, Jari\|Pyrhonen, Seppo\|Syrjanen, Kari
PMID:	22843905

52.
Journal:	Carcinogenesis. 2012 Sep;33(9):1664-73.
Title:	HIF-1alpha-induced histone demethylase JMJD2B contributes to the malignant phenotype of colorectal cancer cells via an epigenetic mechanism.
Author:	Fu, Linna\|Chen, Lisha\|Yang, Jie\|Ye, Ting\|Chen, Yingxuan\|Fang, Jingyuan
PMID:	22745382

53.
Journal:	Clin Cancer Res. 2012 Jun 1;18(11):3100-11.
Title:	Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy.
Author:	McIntyre, Alan\|Patiar, Shalini\|Wigfield, Simon\|Li, Ji-Liang\|Ledaki, Ioanna\|Turley, Helen\|Leek, Russell\|Snell, Cameron\|Gatter, Kevin\|Sly, William S\|Vaughan-Jones, Richard D\|Swietach, Pawel\|Harris, Adrian L
PMID:	22498007

54.
Journal:	Clin Exp Metastasis. 2012 Aug;29(6):541-9.
Title:	The histological growth pattern of colorectal cancer liver metastases has prognostic value.
Author:	Van den Eynden, Gert G\|Bird, Nigel C\|Majeed, Ali W\|Van Laere, Steven\|Dirix, Luc Y\|Vermeulen, Peter B
PMID:	22476470

55.
Journal:	Expert Opin Ther Pat. 2012 Oct;22(10):1251-5.
Title:	Amide derivatives of benzene-sulfonanilide, pharmaceutical composition thereof and method for cancer treatment using the same (US20120095092).
Author:	Supuran, Claudiu T
PMID:	22849544

56.
Journal:	Radiother Oncol. 2013 Sep;108(3):523-8.
Title:	Targeting carbonic anhydrase IX by nitroimidazole based sulfamides enhances the therapeutic effect of tumor irradiation: a new concept of dual targeting drugs.
Author:	Dubois, Ludwig\|Peeters, Sarah G J A\|van Kuijk, Simon J A\|Yaromina, Ala\|Lieuwes, Natasja G\|Saraya, Ruchi\|Biemans, Rianne\|Rami, Marouan\|Parvathaneni, Nanda Kumar\|Vullo, Daniela\|Vooijs, Marc\|Supuran, Claudiu T\|Winum, Jean-Yves\|Lambin, Philippe
PMID:	23849171

57.
Journal:	Evid Based Complement Alternat Med. 2013;2013:974313.
Title:	Activation of AMP-Activated Protein Kinase alpha and Extracelluar Signal-Regulated Kinase Mediates CB-PIC-Induced Apoptosis in Hypoxic SW620 Colorectal Cancer Cells.
Author:	Cho, Sung-Yun\|Lee, Hyo-Jeong\|Lee, Hyo-Jung\|Jung, Deok-Beom\|Kim, Hyunseok\|Sohn, Eun Jung\|Kim, Bonglee\|Jung, Ji Hoon\|Kwon, Byoung-Mog\|Kim, Sung-Hoon
PMID:	23589723

58.
Journal:	Mol Imaging. 2013 Jan-Feb;12(1):49-58.
Title:	Pharmacologic activation of tumor hypoxia: a means to increase tumor 2-deoxy-2-[18F]fluoro-D-glucose uptake?
Author:	Mees, Gilles\|Dierckx, Rudi\|Vangestel, Christel\|Laukens, Debby\|Van Damme, Nancy\|Van de Wiele, Christophe
PMID:	23348791

59.
Journal:	Invest New Drugs. 2013 Aug;31(4):881-90.
Title:	Monitoring the effects of bevacizumab beyond progression in a murine colorectal cancer model: a functional imaging approach.
Author:	Heijmen, L\|Punt, C J A\|Ter Voert, E G W\|de Geus-Oei, L F\|Heerschap, A\|Bussink, J\|Sweep, C G J\|Zerbi, V\|Oyen, W J G\|Span, P N\|Boerman, O\|van Laarhoven, H W M
PMID:	23325291

60.
Journal:	Int J Radiat Biol. 2013 Jan;89(1):9-15.
Title:	Investigation of possible endogenous hypoxia markers in colorectal cancer.
Author:	Verstraete, Maud\|Debucquoy, Annelies\|Devos, Ellen\|Sagaert, Xavier\|Penninckx, Freddy\|Begg, Adrian\|Haustermans, Karin
PMID:	22852555

61.
Journal:	Eur J Cardiothorac Surg. 2014 Jul;46(1):92-9.
Title:	Carbonic anhydrase IX is associated with early pulmonary spreading of primary colorectal carcinoma and tobacco smoking.
Author:	Schweiger, Thomas\|Kollmann, Dagmar\|Nikolowsky, Christoph\|Traxler, Denise\|Guenova, Emmanuella\|Lang, Gyorgy\|Birner, Peter\|Klepetko, Walter\|Ankersmit, Hendrik Jan\|Hoetzenecker, Konrad
PMID:	24321995

62.
Journal:	Contrast Media Mol Imaging. 2014 May-Jun;9(3):237-45.
Title:	Monitoring hypoxia and vasculature during bevacizumab treatment in a murine colorectal cancer model.
Author:	Heijmen, L\|Ter Voert, E G W\|Punt, C J A\|Heerschap, A\|Oyen, W J G\|Bussink, J\|Sweep, C G J\|Laverman, P\|Span, P N\|de Geus-Oei, L F\|Boerman, O C\|van Laarhoven, H W M
PMID:	24700751

63.
Journal:	Radiother Oncol. 2014 May;111(2):237-42.
Title:	Blood biomarkers are helpful in the prediction of response to chemoradiation in rectal cancer: a prospective, hypothesis driven study on patients with locally advanced rectal cancer.
Author:	Buijsen, Jeroen\|van Stiphout, Ruud G\|Menheere, Paul P C A\|Lammering, Guido\|Lambin, Philippe
PMID:	24746569

64.
Journal:	Oncotarget. 2015 Oct 27;6(33):34732-44.
Title:	Visualizing the antivascular effect of bortezomib on the hypoxic tumor microenvironment.
Author:	Sun, Xiaorong\|Ackerstaff, Ellen\|He, Fuqiu\|Xing, Ligang\|Hsiao, Hung Tsung\|Koutcher, Jason A\|Ling, C Clifton\|Li, Gloria C
PMID:	26416246

65.
Journal:	Int J Mol Sci. 2015 Nov 11;16(11):26936-52.
Title:	Exploring Different Strategies for Efficient Delivery of Colorectal Cancer Therapy.
Author:	Lin, Congcong\|Ng, Huei Leng Helena\|Pan, Weisan\|Chen, Hubiao\|Zhang, Ge\|Bian, Zhaoxiang\|Lu, Aiping\|Yang, Zhijun
PMID:	26569228

66.
Journal:	Oncotarget. 2015 Nov 3;6(34):36139-55.
Title:	Sulfonamide derivative targeting carbonic anhydrase IX as a nuclear imaging probe for colorectal cancer detection in vivo.
Author:	Guan, Siao-Syun\|Cheng, Chun-Chia\|Ho, Ai-Sheng\|Wang, Chia-Chi\|Luo, Tsai-Yueh\|Liao, Tse-Zung\|Chang, Jungshan\|Wu, Cheng-Tien\|Liu, Shing-Hwa
PMID:	26447758

67.
Journal:	Cancer Res. 2015 Oct 1;75(19):4109-18.
Title:	Carbonic Anhydrase Activity Monitored In Vivo by Hyperpolarized 13C-Magnetic Resonance Spectroscopy Demonstrates Its Importance for pH Regulation in Tumors.
Author:	Gallagher, Ferdia A\|Sladen, Helen\|Kettunen, Mikko I\|Serrao, Eva M\|Rodrigues, Tiago B\|Wright, Alan\|Gill, Andrew B\|McGuire, Sarah\|Booth, Thomas C\|Boren, Joan\|McIntyre, Alan\|Miller, Jodi L\|Lee, Shen-Han\|Honess, Davina\|Day, Sam E\|Hu, De-En\|Howat, William J\|Ha
PMID:	26249175

68.
Journal:	BMC Cancer. 2015 Jul 24;15:543.
Title:	Early increase in circulating carbonic anhydrase IX during neoadjuvant treatment predicts favourable outcome in locally advanced rectal cancer.
Author:	Hektoen, Helga Helseth\|Flatmark, Kjersti\|Andersson, Yvonne\|Dueland, Svein\|Redalen, Kathrine Roe\|Ree, Anne Hansen
PMID:	26205955

69.
Journal:	Br J Cancer. 2015 Apr 14;112(8):1314-25.
Title:	Combining bevacizumab and chemoradiation in rectal cancer. Translational results of the AXEBeam trial.
Author:	Verstraete, M\|Debucquoy, A\|Dekervel, J\|van Pelt, J\|Verslype, C\|Devos, E\|Chiritescu, G\|Dumon, K\|D'Hoore, A\|Gevaert, O\|Sagaert, X\|Van Cutsem, E\|Haustermans, K
PMID:	25867261

70.
Journal:	Sci Rep. 2015 Mar 18;5:9247.
Title:	Overexpression of DHX32 contributes to the growth and metastasis of colorectal cancer.
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PMID:	25782664

71.
Journal:	Histopathology. 2015 Jun;66(7):982-90.
Title:	Tumour budding is associated with hypoxia at the advancing front of colorectal cancer.
Author:	Righi, Alberto\|Sarotto, Ivana\|Casorzo, Laura\|Cavalchini, Silvia\|Frangipane, Elena\|Risio, Mauro
PMID:	25381897

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Journal:	Int J Biol Markers. 2015 Feb 24;30(1):e73-80.
Title:	An exploratory biomarker study in metastatic tumors from colorectal cancer patients treated with bevacizumab.
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PMID:	24980447

73.
Journal:	J Med Chem. 2015 May 14;58(9):3975-83.
Title:	6-Substituted sulfocoumarins are selective carbonic anhdydrase IX and XII inhibitors with significant cytotoxicity against colorectal cancer cells.
Author:	Grandane, Aiga\|Tanc, Muhammet\|Di Cesare Mannelli, Lorenzo\|Carta, Fabrizio\|Ghelardini, Carla\|Zalubovskis, Raivis\|Supuran, Claudiu T
PMID:	25875209

74.
Journal:	Biol Pharm Bull. 2016;39(11):1830-1838.
Title:	Isorhamnetin Inhibits Reactive Oxygen Species-Dependent Hypoxia Inducible Factor (HIF)-1alpha Accumulation.
Author:	Seo, Suho\|Seo, Kyuhwa\|Ki, Sung Hwan\|Shin, Sang Mi
PMID:	27803454

75.
Journal:	BMC Cancer. 2016 Nov 18;16(1):902.
Title:	Hypoxic resistance of KRAS mutant tumor cells to 3-Bromopyruvate is counteracted by Prima-1 and reversed by N-acetylcysteine.
Author:	Orue, Andrea\|Chavez, Valery\|Strasberg-Rieber, Mary\|Rieber, Manuel
PMID:	27863474

76.
Journal:	Mol Pharm. 2016 Jul 5;13(7):2497-506.
Title:	Dynamic Contrast Enhanced MRI Assessing the Antiangiogenic Effect of Silencing HIF-1alpha with Targeted Multifunctional ECO/siRNA Nanoparticles.
Author:	Malamas, Anthony S\|Jin, Erlei\|Gujrati, Maneesh\|Lu, Zheng-Rong
PMID:	27264671

77.
Journal:	Mol Pharm. 2016 Mar 7;13(3):1137-46.
Title:	PET Imaging of Carbonic Anhydrase IX Expression of HT-29 Tumor Xenograft Mice with (68)Ga-Labeled Benzenesulfonamides.
Author:	Lau, Joseph\|Zhang, Zhengxing\|Jenni, Silvia\|Kuo, Hsiou-Ting\|Liu, Zhibo\|Vullo, Daniela\|Supuran, Claudiu T\|Lin, Kuo-Shyan\|Benard, Francois
PMID:	26866675

78.
Journal:	Adv Exp Med Biol. 2016;876:195-200.
Title:	Hypoxia-Associated Marker CA IX Does Not Predict the Response of Locally Advanced Rectal Cancers to Neoadjuvant Chemoradiotherapy.
Author:	Mayer, Arnulf\|Vaupel, Peter\|Oberholzer, Katja\|Ebert, Maren\|Dimitrow, Marc\|Kreft, Andreas\|Mueller-Klieser, Wolfgang\|Schmidberger, Heinz
PMID:	26782212

79.
Journal:	Eur J Med Chem. 2016 Feb 15;109:247-53.
Title:	Development of certain new 2-substituted-quinazolin-4-yl-aminobenzenesulfonamide as potential antitumor agents.
Author:	Alafeefy, Ahmed M\|Ahmad, Rehan\|Abdulla, Maha\|Eldehna, Wagdy M\|Al-Tamimi, Abdul-Malek S\|Abdel-Aziz, Hatem A\|Al-Obaid, Omar\|Carta, Fabrizio\|Al-Kahtani, Abdulla A\|Supuran, Claudiu T
PMID:	26774930

80.
Journal:	Int J Oncol. 2016 Jan;48(1):115-22.
Title:	Characteristics of carbonic anhydrase 9 expressing cells in human intestinal crypt base.
Author:	Takahashi, Hidekazu\|Suzuki, Yozo\|Nishimura, Junichi\|Haraguchi, Naotsugu\|Ohtsuka, Masahisa\|Miyazaki, Susumu\|Uemura, Mamoru\|Hata, Taishi\|Takemasa, Ichiro\|Mizushima, Tsunekazu\|Yamamoto, Hirofumi\|Doki, Yuichiro\|Mori, Masaki
PMID:	26648507

81.
Journal:	J Enzyme Inhib Med Chem. 2016 Oct;31(5):779-86.
Title:	Sulfamate inhibitor S4 influences carbonic anhydrase IX ectodomain shedding in colorectal carcinoma cells.
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PMID:	26244271

82.
Journal:	J Steroid Biochem Mol Biol. 2017 Oct;173:130-138.
Title:	Integrative genomic approaches to dissect clinically-significant relationships between the VDR cistrome and gene expression in primary colon cancer.
Author:	Long, Mark D\|Campbell, Moray J
PMID:	28027912

83.
Journal:	Oncotarget. 2017 Feb 7;8(6):10225-10237.
Title:	Genetic disruption of the pHi-regulating proteins Na+/H+ exchanger 1 (SLC9A1) and carbonic anhydrase 9 severely reduces growth of colon cancer cells.
Author:	Parks, Scott K\|Cormerais, Yann\|Durivault, Jerome\|Pouyssegur, Jacques
PMID:	28055960

84.
Journal:	J Enzyme Inhib Med Chem. 2017 Dec;32(1):722-730.
Title:	Design, synthesis and evaluation of (18)F-labeled cationic carbonic anhydrase IX inhibitors for PET imaging.
Author:	Zhang, Zhengxing\|Lau, Joseph\|Zhang, Chengcheng\|Colpo, Nadine\|Nocentini, Alessio\|Supuran, Claudiu T\|Benard, Francois\|Lin, Kuo-Shyan
PMID:	28385087

85.
Journal:	Pathol Res Pract. 2017 Jul;213(7):783-792.
Title:	Clinicopathologic and prognostic significance of immunohistochemical expression of HIF-1alpha, CXCR4 and CA9 in colorectal carcinoma.
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PMID:	28554753

86.
Journal:	J Mol Med (Berl). 2017 Dec;95(12):1341-1353.
Title:	Carbonic anhydrase IX inhibition affects viability of cancer cells adapted to extracellular acidosis.
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PMID:	28929255

87.
Journal:	ACS Med Chem Lett. 2017 Nov 21;8(12):1314-1319.
Title:	Discovery of New Sulfonamide Carbonic Anhydrase IX Inhibitors Incorporating Nitrogenous Bases.
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PMID:	29259754

88.
Journal:	J Bioenerg Biomembr. 2018 Apr;50(2):107-116.
Title:	The cytotoxic, apoptotic and oxidative effects of carbonic anhydrase IX inhibitor on colorectal cancer cells.
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PMID:	29520697

89.
Journal:	Neoplasia. 2018 Jul;20(7):668-677.
Title:	Biologic Response of Colorectal Cancer Xenograft Tumors to Sequential Treatment with Panitumumab and Bevacizumab.
Author:	Taniguchi, Hiroya\|Baba, Yuji\|Sagiya, Yoji\|Gotou, Masamitsu\|Nakamura, Kazuhide\|Sawada, Hiroshi\|Yamanaka, Kazunori\|Sakakibara, Yukiko\|Mori, Ikuo\|Hikichi, Yukiko\|Soeda, Junpei\|Baba, Hideo
PMID:	29802988

90.
Journal:	Bioorg Chem. 2018 Sep 7;81:425-432.
Title:	Tumor-associated carbonic anhydrase isoform IX and XII inhibitory properties of certain isatin-bearing sulfonamides endowed with in vitro antitumor activity towards colon cancer.
Author:	Eldehna, Wagdy M\|Nocentini, Alessio\|Al-Rashood, Sara T\|Hassan, Ghada S\|Alkahtani, Hamad M\|Almehizia, Abdulrahman A\|Reda, Ahmed M\|Abdel-Aziz, Hatem A\|Supuran, Claudiu T
PMID:	30219719