Primary Site >> Colorectal Cancer

Gene >> BUB1B

Journal: Jpn J Cancer Res. 2000 May;91(5):504-9.
Title: Infrequent mutation of the hBUB1 and hBUBR1 genes in human lung cancer.
Author: Sato, M|Sekido, Y|Horio, Y|Takahashi, M|Saito, H|Minna, J D|Shimokata, K|Hasegawa, Y
PMID: 10835495
Journal: Cancer Lett. 2000 May 1;152(2):193-9.
Title: Mutation and expression analysis of human BUB1 and BUB1B in aneuploid breast cancer cell lines.
Author: Myrie, K A|Percy, M J|Azim, J N|Neeley, C K|Petty, E M
PMID: 10773412
Journal: Cancer Res. 2002 Jan 1;62(1):13-7.
Title: Genetic and epigenetic inactivation of mitotic checkpoint genes hBUB1 and hBUBR1 and their relationship to survival.
Author: Shichiri, Masayoshi|Yoshinaga, Keigo|Hisatomi, Hisashi|Sugihara, Kenichi|Hirata, Yukio
PMID: 11782350
Journal: Cancer Metastasis Rev. 2004 Jan-Jun;23(1-2):11-27.
Title: Genomic instability and colon cancer.
Author: Grady, William M
PMID: 15000146
Journal: Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8699-704.
Title: Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint.
Author: Kops, Geert J P L|Foltz, Daniel R|Cleveland, Don W
PMID: 15159543
Journal: Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4365-70. Epub 2005 Mar 14.
Title: Colonic tumorigenesis in BubR1+/-ApcMin/+ compound mutant mice is linked to premature separation of sister chromatids and enhanced genomic instability.
Author: Rao, Chinthalapally V|Yang, Yang-Ming|Swamy, Malisetty V|Liu, Tongyi|Fang, Yuqiang|Mahmood, Radma|Jhanwar-Uniyal, Meena|Dai, Wei
PMID: 15767571
Journal: Cell Cycle. 2006 Apr;5(8):818-23.
Title: Chromosomal instability, colorectal cancer and taxane resistance.
Author: Swanton, Charles|Tomlinson, Ian|Downward, Julian
PMID: 16628000
Journal: J Cell Biol. 2007 Jan 15;176(2):183-95.
Title: Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis.
Author: Dikovskaya, Dina|Schiffmann, David|Newton, Ian P|Oakley, Abigail|Kroboth, Karin|Sansom, Owen|Jamieson, Thomas J|Meniel, Valerie|Clarke, Alan|Nathke, Inke S
PMID: 17227893
Journal: Cell Cycle. 2007 Feb 1;6(3):339-52. Epub 2007 Feb 3.
Title: c-MYC delays prometaphase by direct transactivation of MAD2 and BubR1: identification of mechanisms underlying c-MYC-induced DNA damage and chromosomal instability.
Author: Menssen, Antje|Epanchintsev, Alexey|Lodygin, Dmitri|Rezaei, Nousin|Jung, Peter|Verdoodt, Berlinda|Diebold, Joachim|Hermeking, Heiko
PMID: 17297307
Journal: J Clin Pathol. 2007 Dec;60(12):1403-8.
Title: Spindle proteins Aurora A and BUB1B, but not Mad2, are aberrantly expressed in dysplastic mucosa of patients with longstanding ulcerative colitis.
Author: Burum-Auensen, E|Deangelis, P M|Schjolberg, A R|Roislien, Jo|Andersen, S N|Clausen, O P F
PMID: 17322345
Journal: Exp Mol Med. 2007 Apr 30;39(2):195-204.
Title: Differential promoter methylation may be a key molecular mechanism in regulating BubR1 expression in cancer cells.
Author: Park, Hye-Young|Jeon, Yoon-Kyung|Shin, Hyun-Jin|Kim, Il-Jin|Kang, Hio-Chung|Jeong, Sook-Jung|Chung, Doo-Hyun|Lee, Chang-Woo
PMID: 17464181
Journal: Gastroenterology. 2007 Jun;132(7):2448-58. Epub 2007 Mar 19.
Title: APC inactivation associates with abnormal mitosis completion and concomitant BUB1B/MAD2L1 up-regulation.
Author: Abal, Miguel|Obrador-Hevia, Antonia|Janssen, Klaus-Peter|Casadome, Laura|Menendez, Mireia|Carpentier, Sabrina|Barillot, Emmanuel|Wagner, Mechthild|Ansorge, Wilhelm|Moeslein, Gabriela|Fsihi, Hafida|Bezrookove, Vladimir|Reventos, Jaume|Louvard, Daniel|Capel
PMID: 17570218
Journal: PLoS One. 2007 Dec 26;2(12):e1337.
Title: Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway.
Author: Vitale, Ilio|Galluzzi, Lorenzo|Vivet, Sonia|Nanty, Lisa|Dessen, Philippe|Senovilla, Laura|Olaussen, Ken A|Lazar, Vladimir|Prudhomme, Michelle|Golsteyn, Roy M|Castedo, Maria|Kroemer, Guido
PMID: 18159231
Journal: Cell Prolif. 2008 Aug;41(4):645-59.
Title: Reduced level of the spindle checkpoint protein BUB1B is associated with aneuploidy in colorectal cancers.
Author: Burum-Auensen, E|DeAngelis, P M|Schjolberg, A R|Roislien, J|Mjaland, O|Clausen, O P F
PMID: 18699967
Journal: PLoS One. 2009;4(2):e4388.
Title: Five quantitative trait loci control radiation-induced adenoma multiplicity in Mom1R Apc Min/+ mice.
Author: Elahi, Eiram|Suraweera, Nirosha|Volikos, Emmanouil|Haines, Jackie|Brown, Natalie|Davidson, Gerovie|Churchman, Mike|Ilyas, Mohammed|Tomlinson, Ian|Silver, Andrew
PMID: 19194513
Journal: Anticancer Res. 2009 Nov;29(11):4381-7.
Title: Aneuploidy is associated with TP53 expression but not with BRCA1 or TERT expression in sporadic colorectal cancer.
Author: Schjolberg, Aasa R|Clausen, Ole Petter F|Burum-Auensen, Espen|De Angelis, Paula M
PMID: 20032382
Journal: Int J Biochem Cell Biol. 2010 Feb;42(2):318-28.
Title: Checkpoint kinase 1 modulates sensitivity to cisplatin after spindle checkpoint activation in SW620 cells.
Author: Peralta-Sastre, A|Manguan-Garcia, C|de Luis, A|Belda-Iniesta, C|Moreno, S|Perona, R|Sanchez-Perez, I
PMID: 19931410
Journal: Nutr Cancer. 2010;62(6):825-40.
Title: Hydrophobic bile acid-induced micronuclei formation, mitotic perturbations, and decreases in spindle checkpoint proteins: relevance to genomic instability in colon carcinogenesis.
Author: Payne, Claire M|Crowley-Skillicorn, Cheray|Bernstein, Carol|Holubec, Hana|Moyer, Mary Pat|Bernstein, Harris
PMID: 20661832
Journal: Br J Cancer. 2013 May 28;108(10):2013-20.
Title: 212Pb-radioimmunotherapy potentiates paclitaxel-induced cell killing efficacy by perturbing the mitotic spindle checkpoint.
Author: Yong, K J|Milenic, D E|Baidoo, K E|Brechbiel, M W
PMID: 23632482
Journal: Anticancer Res. 2014 Oct;34(10):5421-7.
Title: Aberrations of BUBR1 and TP53 gene mutually associated with chromosomal instability in human colorectal cancer.
Author: Zhao, Yan|Ando, Koji|Oki, Eiji|Ikawa-Yoshida, Ayae|Ida, Satoshi|Kimura, Yasue|Saeki, Hiroshi|Kitao, Hiroyuki|Morita, Masaru|Maehara, Yoshihiko
PMID: 25275037
Journal: Oncotarget. 2015 Jul 10;6(19):17342-53.
Title: Deregulation of HMGA1 expression induces chromosome instability through regulation of spindle assembly checkpoint genes.
Author: Pierantoni, Giovanna Maria|Conte, Andrea|Rinaldo, Cinzia|Tornincasa, Mara|Gerlini, Raffaele|Federico, Antonella|Valente, Davide|Medico, Enzo|Fusco, Alfredo
PMID: 26009897
Journal: Cell Cycle. 2016;15(6):812-8.
Title: Hmga1 null mouse embryonic fibroblasts display downregulation of spindle assembly checkpoint gene expression associated to nuclear and karyotypic abnormalities.
Author: Pierantoni, Giovanna Maria|Conte, Andrea|Rinaldo, Cinzia|Tornincasa, Mara|Gerlini, Raffaele|Valente, Davide|Izzo, Antonella|Fusco, Alfredo
PMID: 26889953
Journal: Genes Chromosomes Cancer. 2016 Nov;55(11):855-63.
Title: Prevalence of germline mutations in the spindle assembly checkpoint gene BUB1B in individuals with early-onset colorectal cancer.
Author: Hahn, Marc-Manuel|Vreede, Lilian|Bemelmans, Sonja A S A|van der Looij, Erica|van Kessel, Ad Geurts|Schackert, Hans K|Ligtenberg, Marjolijn J L|Hoogerbrugge, Nicoline|Kuiper, Roland P|de Voer, Richarda M
PMID: 27239782
Journal: Int J Mol Sci. 2016 Sep 3;17(9). pii: ijms17091437.
Title: Phyllanthus emblica Fruit Extract Activates Spindle Assembly Checkpoint, Prevents Mitotic Aberrations and Genomic Instability in Human Colon Epithelial NCM460 Cells.
Author: Guo, Xihan|Wang, Xu
PMID: 27598149
Journal: Oncol Lett. 2016 Dec;12(6):5092-5098.
Title: Identification of potential therapeutic targets for colorectal cancer by bioinformatics analysis.
Author: Yan, Ming|Song, Maomin|Bai, Rixing|Cheng, Shi|Yan, Wenmao
PMID: 28105216
Journal: Oncology. 2017;92(1):48-54.
Title: The Expression of CCAT2, a Novel Long Noncoding RNA Transcript, and rs6983267 Single-Nucleotide Polymorphism Genotypes in Colorectal Cancers.
Author: Kasagi, Yuta|Oki, Eiji|Ando, Koji|Ito, Shuhei|Iguchi, Tomohiro|Sugiyama, Masahiko|Nakashima, Yuichiro|Ohgaki, Kippei|Saeki, Hiroshi|Mimori, Koshi|Maehara, Yoshihiko
PMID: 27875818
Journal: Mol Cell Probes. 2018 Feb;37:39-47.
Title: Identification of genes involved in the four stages of colorectal cancer: Gene expression profiling.
Author: Shi, Guiling|Wang, Yijia|Zhang, Chunze|Zhao, Zhenying|Sun, Xiuying|Zhang, Shiwu|Fan, Jinling|Zhou, Cunxia|Zhang, Jihong|Zhang, Huijuan|Liu, Jun
PMID: 29179987
Journal: PLoS One. 2018 Apr 11;13(4):e0194098.
Title: Germline mutations in candidate predisposition genes in individuals with cutaneous melanoma and at least two independent additional primary cancers.
Author: Pritchard, Antonia L|Johansson, Peter A|Nathan, Vaishnavi|Howlie, Madeleine|Symmons, Judith|Palmer, Jane M|Hayward, Nicholas K
PMID: 29641532